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| 1 | Differential responses of short-term soil respiration dynamics to the experimental addition of nitrogen and water in the temperate semi-arid steppe of Inner Mongolia, China显示文摘We examined the effects of simulated rainfall and increasing N supply of different levels on CO2 pulse emission from typical Inner Mongolian steppe soil using the static opaque chamber technique, respectively in a dry June and a rainy August. The treatments included NH4NO3 additions at rates of 0, 5, 10, and 20 g N/(m2·year) with or without water. Immediately after the experimental simulated rainfall events, the CO2 effluxes in the watering plots without N addition(WCK) increased greatly and reached the maximum value at 2 hr. However, the efflux level reverted to the background level within 48 hr. The cumulative CO2 effluxes in the soil ranged from 5.60 to 6.49 g C/m2over 48 hr after a single water application, thus showing an increase of approximately 148.64% and 48.36% in the effluxes during both observation periods. By contrast, the addition of different N levels without water addition did not result in a significant change in soil respiration in the short term. Two-way ANOVA showed that the effects of the interaction between water and N addition were insignificant in short-term soil CO2 effluxes in the soil. The cumulative soil CO2fluxes of different treatments over 48 hr accounted for approximately 5.34% to 6.91% and 2.36% to 2.93% of annual C emission in both experimental periods. These results stress the need for improving the sampling frequency after rainfall in future studies to ensure more accurate evaluation of the grassland C emission contribution. | Yuchun Qi Xinchao Liu Yunshe Dong Qin Peng Yating He Liangjie Sun Junqiang Jia Congcong Cao | 2014 | Journal of Environmental Sciences2014，26，4： | 17 |
| 2 | Litter decomposition and C and N dynamics as affected by N additions in a semi-arid temperate steppe, Inner Mongolia of China显示文摘Litter decomposition is the fundamental process in nutrient cycling and soil carbon(C) sequestration in terrestrial ecosystems. The global-wide increase in nitrogen(N) inputs is expected to alter litter decomposition and,ultimately, affect ecosystem C storage and nutrient status. Temperate grassland ecosystems in China are usually N-deficient and particularly sensitive to the changes in exogenous N additions. In this paper, we conducted a 1,200-day in situ experiment in a typical semi-arid temperate steppe in Inner Mongolia to investigate the litter decomposition as well as the dynamics of litter C and N concentrations under three N addition levels(low N with 50 kg N/(hm2?a)(LN), medium N with 100 kg N/(hm2?a)(MN), and high N with 200 kg N/(hm2?a)(HN)) and three N addition forms(ammonium-N-based with 100 kg N/(hm2?a) as ammonium sulfate(AS), nitrate-N-based with 100 kg N/(hm2?a) as sodium nitrate(SN), and mixed-N-based with 100 kg N/(hm2?a) as calcium ammonium nitrate(CAN)) compared to control with no N addition(CK). The results indicated that the litter mass remaining in all N treatments exhibited a similar decomposition pattern: fast decomposition within the initial 120 days, followed by a relatively slow decomposition in the remaining observation period(120–1,200 days). The decomposition pattern in each treatment was fitted well in two split-phase models, namely, a single exponential decay model in phase I(<398 days) and a linear decay function in phase II(≥398 days). The three N addition levels exerted insignificant effects on litter decomposition in the early stages(<398 days, phase I; P>0.05). However, MN and HN treatments inhibited litter mass loss after 398 and 746 days, respectively(P<0.05). AS and SN treatments exerted similar effects on litter mass remaining during the entire decomposition period(P>0.05). The effects of these two N addition forms differed greatly from those of CAN after 746 and 1,053 days, respectively(P<0.05). During the decomposition period, N concentrations in the decomposing litter increased whereas C concentrations decreased, which also led to an exponential decrease in litter C:N ratios in all treatments. No significant effects were induced by N addition levels and forms on litter C and N concentrations(P>0.05). Our results indicated that exogenous N additions could exhibit neutral or inhibitory effects on litter decomposition, and the inhibitory effects of N additions on litter decomposition in the final decay stages are not caused by the changes in the chemical qualities of the litter, such as endogenous N and C concentrations. These results will provide an important data basis for the simulation and prediction of C cycle processes in future N-deposition scenarios. | Qin PENG YuChun QI YunShe DONG YaTing HE ShengSheng XIAO XinChao LIU LiangJie SUN JunQiang JIA ShuFang GUO CongCong CAO | 2014 | Journal of Arid Land2014，6，4： | 16 |
| 3 | Effects of a conversion from grassland to cropland on the different soil organic carbon fractions in Inner Mongolia, China显示文摘耕作是除放牧以外影响草地生态系统的最重要的人的活动之一,但是它土壤上的影响总计器官的碳(C) ,特别在有倾向的器官的 C 部分上还充分没被理解。在这份报纸,在土壤收割不同部分的器官的 C 水池的角色在中国,和在不同 C 部分之间的关系的内部蒙古在一个草地大草原区域被调查也被讨论。结果显示在大草原和栽培土地的不同 C 部分的集中都与土壤深度日益增多地减少了。在到为 36 年的春天小麦地的从大草原的变换以后,在 0~100 厘米土壤深度的全部的器官的碳( TOC )集中在12.3%~28.2%减少了,并且表面土壤地平线的 TOC ,特别那些更显著地 030 厘米减少了( p < 0.01 )。溶解的器官的碳(文档) 和在 040 厘米的深度的微生物引起的生物资源碳(MBC ) 被发现分别地在 66.7% ~ 77.1% 和 36.5% ~ 42.4% 减少了。在 S。baicalensis 大草原,春天小麦地里的到 TOC 的文档在 0.52% 和 0.60% 之间改变了的土壤的比率,和那些仅仅在 0.18%0.20% 的范围。在春天小麦的微生物引起的商(qMBs ) 回答,从 1.11% ~ 1.40% 变化,也是比在 S 的那些低的。baicalensis 大草原,它在 1.50%1.63% 的范围。文档的变化对耕作骚乱更敏感。土壤 TOC,文档,和 MBC 是显著地积极的在 S 与对方一起相关。baicalensis 大草原,但是在春天小麦地里,在文档之间的相互关系和在文档和 MBC 之间的 TOC 和那没到达 0.05 的意义水平。 | QI Yuchun DONG Yunshe PENG Qin XIAO Shengsheng HE Yating LIU Xinchao SUN Liangjie JIA Junqiang YANG Zhijie | 2012 | Journal of Geographical Sciences2012，22，2： | 13 |
| 4 | Spatial-temporal variation in soil respiration and its controlling factors in three steppes of Stipa L. in Inner Mongolia, China显示文摘Grassland is the largest terrestrial ecosystem in China. It is of great significance to measure accurately the soil respiration of different grassland types for the contribution evaluation of the Chinese terrestrial ecosystem’s carbon emission to the atmospheric CO2 concentration. A three-year (2005-2007) field experiment was carried out on three steppes of Stipa L. in the Xilin River Basin, Inner Mongolia, China, using a static opaque chamber technique. The seasonal and interannual variations of soil respiration rates were analyzed, and the annual total soil respiration of the three steppes was estimated. The numerical models between soil respiration and water-heat factors were established respectively. Similar seasonal dynamic and high annual and interannual variations of soil respiration were found in all of the three steppes. In the growing season, the fluctuation of soil respiration was particularly evident. The coefficients of variation (CVs) for soil respiration in different growing seasons ranged from 54% to 93%, and the annual CVs were all above 115%. The interannual CV of soil respiration progressively decreased in the order of Stipa grandis (S. grandis) steppe > Stipa baicalensis (S. baicalensis) steppe > Stipa krylovii (S. krylovii) steppe. The annual total soil respiration for the S. baicalensis steppe was 223.62?299.24 gC m-2 a-1, 150.62-226.99 gC m-2 a-1 for the S. grandis steppe, and 111.31–131.55 gC m-2 a-1 for the S. krylovii steppe, which were consistent with the precipitation gradient. The variation in the best fitting temperature factor explained the 63.5%, 73.0%, and 73.2% change in soil respiration in the three steppes at an annual time scale, and the corresponding Q10 values were 2.16, 2.98, and 2.40, respectively. Moreover, the Q10 values that were calculated by soil temperature at different depths all expressed a 10 cm > 5 cm > surface in the three sampling sites. In the growing season, the soil respiration rates were related mostly to the surface soil moisture, and the 95.2%, 97.4%, and 93.2% variations in soil respiration in the three steppes were explained by the change in soil moisture at a depth of 0-10 cm, respectively. | QI YuChun DONG YunShe LIU LiXin LIU XingRen PENG Qin XIAO ShengSheng HE YaTing | 2010 | Science China Earth Sciences2010，53，5： | 12 |
| 5 | Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair显示文摘There are intense interests in discovering pro regenerative medicine leads that can promote cardiac differentiation and regeneration,as well as repair damaged heart tissues.We have combined zebrafish embryo-based screens with cardiomyogenesis assays to discover selective small molecules that modulate heart development and regeneration with minimal adverse effects.Two related compounds with novel structures,named as Cardiomogen 1 and 2(CDMG1 and CDMG2),were identified for their capacity to promote myocardial hyperplasia through expansion of the cardiac progenitor cell population.We find that Cardiomogen acts as a Wnt inhibitor by targeting p-catenin and reducing Tcf/Lef-mediated transcription in cultured cells.CDMG treatment of amputated zebrafish hearts reduces nuclear p-catenin in injured heart tissue,increases cardiomyocyte(CM)proliferation,and expedites wound healing,thus accelerating cardiac muscle regeneration.Importantly,Cardiomogen can alleviate the functional deterioration of mammalian hearts after myocardial infarction.Injured hearts exposed to CDMG1 display increased newly formed CMs and reduced fibrotic scar tissue,which are in part attributable to the^-catenin reduction.Our findings indicate Cardiomogen as a Wnt inhibitor in enhancing injury-induced CM proliferation and heart regeneration,highlighting the values of embryo-based small molecule screens in discovery of effective and safe medicine leads. | Shuying Xie Wenbin Fu Guangju Yu Xueli Hu Kaa Seng Lai Xiangwen Peng Yating Zhou Xuejiao Zhu Ptamen Christov Leah Sawyer Terri T.Ni Gary A.Sulikowski Zhongzhou Yang Ethan Lee Chunyu Zeng Wei E.Wang Tao P.Zhong | 2020 | Journal of Molecular Cell Biology2020，12，1： | 4 |
| 6 | Research progress of defect-engineered UiO-66(Zr)MOFs for photocatalytic hydrogen production显示文摘In recent years,defect-engineered Zr-based UiO-66 metal-organic frameworks(UiO-66(Zr)metalorganic frameworks(MOFs))have shown huge advantages in catalytic,functional materials,adsorption,and other fields due to their large surface areas,well-ordered porous structures,and flexible tailorability.It is extremely challenging to introduce defect sites in the synthesis of MOFs to regulate the physicochemical properties of materials such as(energy band structure,pore structure,etc.)to obtain an excellent performance.This paper reviews the recent research results of synthesis methods,characterization technologies,and application fields of defect-engineered UiO-66(Zr)MOFs materials in order to provide new insights to synthesize high-performance UiO-66(Zr)MOFs materials and promote the development of UiO-66(Zr)in various fields. | Yating WANG Chaosheng PENG Tao JIANG Xingang LI | 2021 | Frontiers in Energy2021，15，3： | 4 |
| 7 | Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration显示文摘Heart regeneration occurs by dedifferentiation and proliferation of pre-existing cardiomyocytes(CMs).However,the signaling mechanisms by which injury induces CM renewal remain incompletely understood.Here,we find that cardiac injury in zebrafish induces expression of the secreted Wnt inhibitors,including Dickkopf 1(Dkkl),Dkk3,secreted Frizzled-related protein 1(sFrpl),and sFrp2,in cardiac tissue adjacent to injury sites.Experimental blocking of Wnt activity via Dkkl overexpression enhances CM proliferation and heart regeneration,whereas ectopic activation of Wnt8 signaling blunts injury-induced CM dedifferentiation and proliferation.Although Wnt signaling is dampened upon injury,the cytoplasmic β-catenin is unexpectedly increased at disarrayed CM sarcomeres in myocardial wound edges.Our analyses indicated that p21-activated kinase 2(Pak2)is induced at regenerating CMs,where it phosphorylates cytoplasmic β-catenin at Ser 675 and increases its stability at disassembled sarcomeres.Myocardial-specific induction of the phospho-mimeticβ-catenin(S675E)enhances CM dedifferentiation and sarcomere disassembly in response to injury.Conversely,inactivation of Pak2 kinase activity reduces the Ser 675-phosphorylatedβ-catenin(pS675-β-catenin)and attenuates CM sarcomere disorganization and dedifferentiation・Taken together,these findings demonstrate that coordination of Wnt signaling inhibition and Pak2/pS675-βYatenin signaling enhances zebrafish heart regeneration by supporting CM dedifferentiation and proliferation. | Xiangwen Peng Kaa Seng Lai Peilu She Junsu Kang Tingting Wang Guobao Li Yating Zhou jianjian Sun Daqing Jin Xiaolei Xu Lujian Liao Jiandong Liu Ethan Lee Kenneth D.Poss Tao P.Zhong | 2021 | Journal of Molecular Cell Biology2021，13，1： | 3 |
| 8 | Response of soil N_2O emissions to precipitation pulses under different nitrogen availabilities in a semiarid temperate steppe of Inner Mongolia, China显示文摘Short-term nitrous oxide(N2O) pulse emissions caused by precipitation account for a considerable portion of the annual N2O emissions and are greatly influenced by soil nitrogen(N) dynamics. However, in Chinese semiarid temperate steppes, the response of N2O emissions to the coupling changes of precipitation and soil N availability is not yet fully understood. In this study, we conducted two 7-day field experiments in a semiarid temperate typical steppe of Inner Mongolia, China, to investigate the N2O emission pulses resulting from artificial precipitation events(approximately equivalent to 10.0 mm rainfall) under four N addition levels(0, 5, 10 and 20 g N/(m2·a)) using the static opaque chamber technique. The results show that the simulated rainfall during the dry period in 2010 caused greater short-term emission bursts than that during the relatively rainy observation period in 2011(P<0.05). No significant increase was observed for either the N2O peak effluxes or the weekly cumulative emissions(P>0.05) with single water addition. The peak values of N2O efflux increased with the increasing N input. Only the treatments with water and medium(WN10) or high N addition(WN20) significantly increased the cumulative N2O emissions(P<0.01) in both experimental periods. Under drought condition, the variations in soil N2O effluxes were positively correlated with the soil NH4-N concentrations in the three N input treatments(WN5, WN10, and WN20). Besides, the soil moisture and temperature also greatly influenced the N2O pulse emissions, particularly the N2O pulse under the relatively rainy soil condition or in the treatments without N addition(ZN and ZWN). The responses of the plant metabolism to the varying precipitation distribution and the length of drought period prior to rainfall could greatly affect the soil N dynamics and N2O emission pulses in semiarid grasslands. | XinChao LIU YuChun QI YunShe DONG Qin PENG YaTing HE LiangJie SUN JunQiang JIA CongCong CAO | 2014 | Journal of Arid Land2014，6，4： | 3 |
| 9 | Heavy soil drying during mid-to-late grain filling stage of the main crop to reduce yield loss of the ratoon crop in a mechanized rice ratooning system显示文摘Yield loss(Y_(Loss)) in the ratoon crop due to crushing damage to left stubble from mechanical harvesting of the main crop is a constraint for wide adoption of mechanized rice ratooning technology.Soil drying before the harvest of the main crop has been proposed to overcome this problem.The objective of this study was to determine the effect of soil drying during the mid-to-late grain filling stage of the main crop on grain yield of the ratoon crop in a mechanized rice ratooning system.Field experiments were conducted to compare Y_(Loss) between light(LD) and heavy(HD) soil drying treatments in Hubei province,central China in 2017 and 2018.Y_(Loss) was calculated as the percentage of yield reduction in the ratoon crop with the main crop harvested mechanically,relative to the grain yield of the ratoon crop with the main crop harvested manually.In comparison with LD,soil hardness was increased by 42.8%-84.7% in HD at the 5-20 cm soil depth at maturity of the main crop.Soil hardness at 5 and 10 cm depths reached respectively 4.05 and 7.07 kg cm^(-2) in HD.Soil drying treatment did not significantly affect the grain yield of the main crop.Under mechanical harvesting of the main crop,HD increased the grain yield of the ratoon crop by 9.4% relative to LD.Consequently,Y_(Loss) was only 3.4% in HD,in contrast to 16.3% in LD.The differences in grain yield and Y_(Loos) between the two soil drying treatments were explained mainly by panicles m^(-2),which was increased significantly by HD in the track zone of the ratoon crop compared with LD.These results suggest that heavy soil drying practice during the mid-to-late grain filling stage of the main crop is effective for reducing Y_(Loss) of the ratoon crop in a mechanized rice ratooning system. | Chang Zheng Yuechao Wang Shen Yuan Sen Xiao Yating Sun Jianliang Huang Shaobing Peng | 2022 | The Crop Journal2022，10，1： | 3 |
| 10 | Lightweight 3D bioprinting with point by point photocuring显示文摘As photocrosslinkable materials,methacryloyl-modified hydrogels are widely used as bioinks in tissue engineering.Existing printing methods to use these hydrogels,including changing the viscosity of the material or mixing them with other printing components,have been explored,but their application has been limited due to low printing quality or high cost.In addition,the complex operation of bulky equipment restricts the application of these existing printing methods.This study presents a lightweight stereolithography-based three-dimensional(3D)bioprinting system with a smart mechanical and structural design.The developed bioprinter dimensions were 300 mm×300 mm×200 mm and it can be placed on a benchtop.The equipment has a mini bioink chamber to store a small amount of bioink for each printing.We systematically investigated the point-by-point curing process in the 3D bioprinting method,which can print mixed cells accurately and have good biocompatibility.Here,we provide a compact,low-cost stereolithography bioprinting system with excellent biocompatibility for 3D bioprinting with methacryloyl-modified hydrogels.It can be potentially used for drug screening,studying pathological mechanisms,and constructing biological disease models. | Peng Zhang Haoxuan Wang Peng Wang Yating Zheng Linxiang Liu Jun Hu Yande Liu Qing Gao Yong He | 2021 | Bioactive Materials2021，6，5： | 2 |
| 11 | Inhibitory mechanism of angiotensin-converting enzyme inhibitory peptides from black tea显示文摘The aim of this work is to discover the inhibitory mechanism of tea peptides and to analyse the affinities between the peptides and the angiotensin-converting enzyme(ACE)as well as the stability of the complexes using in vitro and in silico methods.Four peptide sequences identified from tea,namely peptides I,II,III,and IV,were used to examine ACE inhibition and kinetics.The half maximal inhibitory concentration(IC_(50))values of the four peptides were(210.03±18.29),(178.91±5.18),(196.31±2.87),and(121.11±3.38)μmol/L,respectively.The results of Lineweaver-Burk plots showed that peptides I,II,and IV inhibited ACE activity in an uncompetitive manner,which requires the presence of substrate.Peptide III inhibited ACE in a noncompetitive manner,for which the presence of substrate is not necessary.The docking simulations showed that the four peptides did not bind to the active sites of ACE,indicating that the four peptides are allosteric inhibitors.The binding free energies calculated from molecular dynamic(MD)simulation were-72.47,-42.20,-52.10,and-67.14 kcal/mol(1 kcal=4.186 kJ),r espectively.The lower IC_(50)value of peptide IV may be attributed to its stability when docking with ACE and changes in the flexibility and unfolding of ACE.These four bioactive peptides with ACE inhibitory ability can be incorporated into novel functional ingredients of black tea. | Yating LU Yu WANG Danyi HUANG Zhuang BIAN Peng LU Dongmei FAN Xiaochang WANG | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，7： | 2 |
| 12 | Filling Ti_(3)C_(2)T_(x)nanosheets into melamine foam towards a highly compressible all-in-one supercapacitor显示文摘The development of compressible supercapacitors strongly relies on the design of electrode materials combining superior compressibility,high conductivity with the stable electrochemical cycling performance.In this work,we report a facile yet scalable strategy to construct a highly compressible supercapacitor by integrating the current collector,active materials and the separator into one device.We use the highly compressive melamine foam(MF)as scaffold and the Ti_(3)C_(2)T_(x)nanosheets as the active materials.Filling the few-layer Ti_(3)C_(2)T_(x)nanosheets into the skeleton of MF by capillary force followed by freeze-drying yields the MF/Ti_(3)C_(2)T_(x)composite with superior structural integrity that can be compressed at a large strain of 50%for 100 cycles.The electrochemical performances of the all-in-one supercapacitor were systematically investigated under diverse compression strains.The improved conductivity and reduced ion diffusion length allow the all-in-one supercapacitor to exhibit fast ion and electron kinetics even at high strain of 60%,delivering a maximal volumetric specific energy of 0.37 mWh∙cm^(-3)at power density of 0.42 mW∙cm^(-3)and extraordinary cycling performance during the 2,500 compression cycles. | Rui Guo Xiying Han Peng Yuan Xuexia He Qi Li Jie Sun Liqin Dang Zonghuai Liu Yating Zhang Zhibin Lei | 2022 | Nano Research2022，15，4： | 1 |
| 13 | HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies显示文摘The hypoxic microenvironment is an essential characteristic of most malignant tu-mors.Notably,hypoxia-inducible factor-1 alpha(HIF-1a)is a key regulatory factor of cellular adaptation to hypoxia,and many critical pathways are correlated with the biological activity of organisms via HIF-1a.In the intra-tumoral hypoxic environment,HIF-1αis highly expressed and contributes to the malignant progression of tumors,which in turn results in a poor prog-nosis in patients.Recently,it has been indicated that HiF-1αinvolves in various critical pro-cesses of life events and tumor development via regulating the expression of HiF-1a target genes,such as cell proliferation and apoptosis,angiogenesis,glucose metabolism,immune response,therapeutic resistance,etc.Apart from solid tumors,accumulating evidence has re-vealed that HiF-1αis also closely associated with the development and progression of hemato-logical malignancies,such as leukemia,lymphoma,and multiple myeloma.Targeted inhibition of HiF-1a can facilitate an increased sensitivity of patients with malignancies to relevant ther-apeutic agents.In the review,we elaborated on the basic structure and biological functions of HIF-1a and summarized their current role in various malignancies.It is expected that they will have future potential fortargeted therapy. | Yan Zhao Cheng Xing Yating Deng Can Ye Hongling Peng | 2024 | Genes & Diseases2024，11，1： | 1 |
| 14 | Technology assessment for clean energy technologies: the case of the Pacific Northwest 显示文摘 | Daim T Yates D Peng Y | 2009 | Technol- ogy in Society2009，31，3： | 1 |
| 15 | Effectiveness of a multifaceted intervention for the improvement of nutritional status and nutrition knowledge of children in poverty-stricken areas in Shaanxi Province, China显示文摘Objectives:Compare the differences between the intervention and control groups in changes of primary outcomes(body mass index[BMI]and waist-to-height ratio[WHtR])and secondary outcomes(nutrition knowledge of children and parents),from baseline to the 6-and 12-month follow-ups;examine the associations of changes in nutrition knowledge of children and their parents with children’s changes in BMI and WHtR.Data sources:Data collected from four schools in two poverty-stricken counties in northern Shaanxi Province in 2020‒2021.Methods:A multifaced intervention program targeted children(promoting healthy diet and nutrition education)and their parents(promoting nutrition knowledge)was conducted in the interventional group.Four schools,with two in each group,were randomly allocated to the intervention or control group,with 814 eligible children aged 7.1 to 12.8 years.The control group conducted myopia promotion.Differences in changes of BMI and WHtR between groups were compared with t-test.Mixed-effects model was used to examine the associations between changes in nutrition knowledge of children and parents with changes in children’s BMI and WHtR.Results:At the 6-month follow-up,the difference in changes in BMI between the intervention and control groups was 0.4 kg/m 2(P<0.001).At the 12-month follow-up,the difference in changes in BMI and WHtR between intervention and control groups was 0.1 kg/m^(2)(P<0.001)and 0.01 kg/m^(2)(P<0.001).In the intervention group,the nutrition knowledge awareness rate of children increased from 16.9%(69/409)at baseline to 21.3%(87/409)at 6-month,and 22.7%(93/409)at 12-month.The awareness rate of nutrition knowledge of parents also fluctuated,from 5.6%(23/409)to 6.6%(27/409)and 5.4%(22/409).However,the difference in changes in nutrition knowledge between intervention and control groups was non-significant.The 6-month follow-up changes in children’s nutrition knowledge scores were negatively associated with changes in BMI in girls(β=−0.26,95%confidence interval[CI]:−0.38 to−0.14,P<0.001),while positively associated with changes in WHtR in boys(β=0.003,95%CI:−0.0002 to 0.005,P=0.035).The 12-month follow-up changes in children’s nutrition knowledge scores were positively associated with changes in children’s WHtR(β=0.003,95%CI:0.0004 to 0.01,P=0.018).Conclusions:The intervention strategies did not reduce the BMI and WHtR of children,and the nutrition knowledge of children and parents increased after the intervention in intervention group.Changes in nutrition knowledge of children and their parents are associated with changes in children’s BMI or WHtR.Interventions with a new focus on obesity are needed to help improve children’s nutritional status in poverty-stricken areas in Shaanxi Province of China. | Cai Zhao Lu Ma Liwang Gao Yan Wu Yating Yan Wen Peng Youfa Wang | 2022 | Global Health Journal2022，6，3： | 1 |
| 16 | Mapping of individual sensory nerve axons from digits to spinal cord with the transparent embedding solvent system显示文摘Achieving uniform optical resolution for a large tissue sample is a major challenge for deep imaging.For conventional tissue clearing methods,loss of resolution and quality in deep regions is inevitable due to limited transparency.Here we describe the Transparent Embedding Solvent System(TESOS)method,which combines tissue clearing,transparent embedding,sectioning and block-face imaging.We used TESOS to acquire volumetric images of uniform resolution for an adult mouse whole-body sample.The TESOS method is highly versatile and can be combined with different microscopy systems to achieve uniformly high resolution.With a light sheet microscope,we imaged the whole body of an adult mouse,including skin,at a uniform 0.8×0.8×3.5μm^(3) voxel resolution within 120 h.With a confocal microscope and a 40×/1.3 numerical aperture objective,we achieved a uniform sub-micron resolution in the whole sample to reveal a complete projection of individual nerve axons within the central or peripheral nervous system.Furthermore,TESOS allowed the first mesoscale connectome mapping of individual sensory neuron axons spanning 5 cm from adult mouse digits to the spinal cord at a uniform sub-micron resolution. | Yating Yi Youqi Li Shiwen Zhang Yi Men Yuhong Wang Dian Jing Jiayi Ding Qingjie Zhu Zexi Chen Xingjun Chen Jun-Liszt Li Yilong Wang Jun Wang Hanchuan Peng Li Zhang Wenjing Luo Jian Q.Feng Yongwen He Woo-Ping Ge Hu Zhao | 2024 | Cell Research2024，34，2： | 0 |
| 17 | Intelligent self-powered sensor based on triboelectric nanogenerator for take-off status monitoring in the sport of triplejumping显示文摘In the era of big data and the Internet of Things,the digital information of athletes is particularly significant in sports competitions.Here,an intelligent self-powered take-off board sensor(TBS)based on triboelectric nanogenerator(TENG)with a solid-wooden substrate is provided for precise detection of athletes’take-off status in the sport of triple-jumping,which is sufficient for triplejumping training judgment with a high accuracy of 1 mm.Meanwhile,a foul alarm system and a distance between the athlete’s foot and take-off line(GAP)measurement system are further developed to provide take-off data for athletes and referees.The induced charges are formed by the TBS during taking-off,and then the real-time exercise data is acquired and processed via the test program.This work presents a self-powered sports sensor for intelligent sports monitoring and promotes the application of TENG-based sensors in intelligent sports. | Jiahui Xu Xuelian Wei Ruonan Li Yapeng Shi Yating Peng Zhiyi Wu Zhong Lin Wang | 2022 | Nano Research2022，15，7： | 0 |
| 18 | Determination of Fosthiazate Residue in Ginger by Gas Chromatography显示文摘[Objectives] An analytical method was established for determining fosthiazate residue in ginger by gas chromatography with flame photometric detector(GC-NPD) to evaluate the safety of fosthiazate in ginger. [Methods] The fosthiazate residue in ginger was extracted with dichloromethane, and subjected to sodium chloride salt-out and liquid-liquid extraction with hexane and dichloromethane(the plant and soil samples had no need for the later two steps). The analysis was performed on gas chromatograph equipped with a flame photometric detector(GC-FPD), and the fosthiazate residue was quantitatively determined by calculating the peak area. [Results] The results of degradation dynamics showed that the half-life of fosthiazate was 7.2-8.7 d in ginger plants, and was 9.9-19.8 d in the soil. The results of the final residue test showed that after applying the fosthiazate granules according to the recommended high dose(active component 58.2 g a.i/m^2,WK) and low dose(38.8 g a.i/m^2,WK) once, the final residual amounts of fosthiazate in the ginger and soil were estimated to be <0.02 mg/kg and <0.02-0.103 mg/kg, respectively, while no fosthiazate residue was detected in all control samples(<0.02 mg/kg). The maximum residue limit(MRL) of fosthiazate in ginger was not established in China, and was 0.2 mg/kg in Japan. [Conclusions] The method was proved to meet the basic requirements of pesticide residue analysis on sensitivity, accuracy and precision and have good linearity. It is recommended that when using fosthiazate granules to control root-knot nematode and root rot in ginger, it is applied at the highest dose of 38.8 g ai/m^2,WK once 30 d before ginger cultivation to treat the soil, and ginger is harvested in the ginger harvest period. | Kailing PENG Yating XIE Chenzhong JIN Xiaoming OU Han XI Xiu LIU Qiangyong SONG Guiping LIANG Zhifu YANG Shunli XIAO Xuye ZHANG | 2019 | Agricultural Biotechnology2019，8，2： | 0 |
| 19 | Study on bone morphology and development of children based on digital three dimensional reconstruction显示文摘This study aims to construct the skeletal system of children at different ages through digital modeling techniques,explore the law of morphological development of childen's skeletal system,so as to provide a reference for the study of children's bone development and digital anatomy.In this study,12 normal boys were selected from 6 age stages(0-6 months,6-12 months,1-3 years old,3-5 years old,5-7 years old,7-10 years old).All patients underwent CT plain scan with a slice thickness of 0.625 mm.The collected CT data was imported into Mimics 19.0 software for three dimensional reconstruction of children's whole body bones.3D printing of children's bone model was used to construct children's bone system.T wo dissected bone specimens were randomly selected and compared with 3D printed models for specific bony landmarks to verify the accuracy of modeling. | Mi Sirong Xie Liang Hu Luying Zhang Feng He Wenyan Liu Guangxing Zhang Zhenwu Yu Huan Zhan Meizhi Liu Yating Sheng Ting Peng Wen Liu Qiangsheng Rao Libing | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 20 | Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization显示文摘Due to their broad functional plasticity,myeloid cells contribute to both liver injury and recovery during acetaminophen overdose-induced acute liver injury(APAP-ALI).A comprehensive understanding of cellular diversity and intercellular crosstalk is essential to elucidate the mechanisms and to develop therapeutic strategies for APAP-ALI treatment.Here,we identified the function of IFN-I in the myeloid compartment during APAP-ALI.Utilizing single-cell RNA sequencing,we characterized the cellular atlas and dynamic progression of liver CD11b+cells post APAP-ALI in WT and STAT2 T403A mice,which was further validated by immunofluorescence staining,bulk RNA-seq,and functional experiments in vitro and in vivo.We identified IFN-I-dependent transcriptional programs in a three-way communication pathway that involved IFN-I synthesis in intermediate restorative macrophages,leading to CSF-1 production in aging neutrophils that ultimately enabled Trem2+restorative macrophage maturation,contributing to efficient liver repair.Overall,we uncovered the heterogeneity of hepatic myeloid cells in APAP-ALI at single-cell resolution and the therapeutic potential of IFN-I in the treatment of APAP-ALI. | Qiaoling Song Shyamasree Datta Xue Liang Xiaohan Xu Paul Pavicic Xiaonan Zhang Yuanyuan Zhao Shan Liu Jun Zhao Yuting Xu Jing Xu Lihong Wu Zhihua Wu Minghui Zhang Zhan Zhao Chunhua Lin Yuxin Wang Peng Han Peng Jiang Yating Qin Wei Li Yingying Zhang Yonglun Luo Ganes Sen George R.Stark Chenyang Zhao Thomas Hamilton Jinbo Yang | 2023 | Cellular & Molecular Immunology2023，20，2： | 0 |
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