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| 1 | Effectiveness of Inactivated COVID-19 Vaccines Against Symptomatic,Pneumonia,and Severe Disease Caused by the Delta Variant:Real World Study and Evidence—China,2021显示文摘Summary What is already known about this topic?Effectiveness of China’s 2 inactivated vaccines(BBIBPCorV and CoronaVac)against pre-Delta severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)variants ranged from 47%to over 90%,depending on the clinical endpoint,and with greater effectiveness against more severe coronavirus disease 2019(COVID-19).During an outbreak in Guangdong,inactivated vaccine effectiveness(VE)against the Delta variant was 70%for symptomatic infection and 100%for severe COVID-19.However,separate or combined VE estimates for the two inactivated vaccines against Delta are not available.What is added by this report?In an outbreak that started in a hospital,VEs of completed primary vaccination with inactivated COVID-19 vaccines against symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant were 51%,61%,and 82%.Completed primary vaccination reduced the risk of progressing from mild to moderate or severe COVID-19 by 74%.VE estimates for BBIBP-CorV and CoronaVac or combined vaccination were similar,and partial vaccination was ineffective.What are the implications for public health practice?Completed primary vaccination with either of the 2 inactivated COVID-19 vaccines reduces risk of symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant.Completion of the completed primary vaccination with two doses is necessary for protection from Delta. | Dan Wu Yanyang Zhang Lin Tang Fuzhen Wang Ying Ye Chao Ma Hui Zheng Wenzhou Yu Lei Cao Yifan Song Abuduwaili Reyimu Xiaoxiao Zhang Haifeng Wang Yifei Nie Mingxia Lu Muge Qi Jun Li Ruolin Wang Kaichao Yang Changshuang Wang Lawrence Everett Rodewald Geroge Fu Gao Zhijie An Zundong Yin | 2022 | China CDC weekly2022，4，4： | 7 |
| 2 | Potent anti-angiogenesis and anti-tumor activity of a nove human anti-VEGF antibody, MIL60显示文摘 | Jing Yang Qun Wang Chunxia Qiao Zhou Lin Xinying Li Yifei Huang Tingting Zhou Yan Li Beifen Shen Ming Lv Jiannan Feng | 2014 | Cellular & Molecular Immunology2014，11，3： | 4 |
| 3 | Blocking the JAK2/STAT3 and ERK pathways suppresses the proliferation of gastrointestinal cancers by inducing apoptosis显示文摘Dysregulated crosstalk between different signaling pathways contributes to tumor development,including resistance to cancer therapy.In the present study,we found that the mitogen-activated extracellular signal-regulated kinase(MEK)inhibitor trametinib failed to suppress the proliferation of PANC-1 and MGC803 cells by activating the Janus kinase 2(JAK2)/signal transducer and activator of transcription 3(STAT3)signaling pathway,while the JAK2 inhibitor fedratinib failed to inhibit the growth of the PANC-1 cells upon stimulation of extracellular signal-regulated kinase(ERK)signaling.In particular,the most prominent enhancement of the anti-proliferative effect resulted from the concurrent blockage of the JAK2/STAT3 and ERK signaling pathways.Furthermore,the combination of the two inhibitors resulted in a reduced tumor burden in mice.Our evidence suggests novel crosstalk between JAK2/STAT3 and ERK signaling in gastric cancer(GC)and pancreatic ductal adenocarcinoma(PDAC)cells and provides a therapeutic strategy to overcome potential resistance in gastrointestinal cancer. | Xi WANG Chunyan DAI Yifei YIN Lin WU Weiyang JIN Yufei FU Zhe CHEN Ke HAO Bin LU | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，6： | 4 |
| 4 | Phylogenetic positions of some genera and species of the family Buccinidae (Gastropoda: Mollusca) from China based on ribosomal RNA and COI sequences显示文摘A phylogenetic analysis of members of the family Buccinidae was conducted using 18S rRNA gene, 28S rRNA gene and the mitochondrial cytochrome oxidase Ⅰ gene. We studied 18 species of Buccinidae that belong to eight different genera and inhabit the China coastal seas. We analyzed the patterns of divergence between an outgroup and basal ingroup taxa, the monophyly of the genus Neptunea, and the position of one unnamed species within the Buccinidae. A phylogenetic tree (neighbor-joining (NJ) method) was reconstructed based on the sequences of 18S rRNA, 28S rRNA and COI, with Rapana venosa as outgroup. The NJ tree indicated that the 18 species could be divided into five groups. The genus Buccinum was monophyletic, whereas Neptunea was shown to be paraphyletic since it included Siphonalia subdilatata and Neptunea sp., a new species. This novel species otherwise clustered consistently with Neptunea cumingi in three other phylogenetic trees, showing a low genetic distance and divergence percentage of sequences belonging to the genus Neptunea. A smaller genetic distance and a smaller difference of 18S rRNA, 28S rRNA and COI sequences between Neptunea cumingii and Neptunea arthritica cumingii confirmed them to be the same species. | HOU Lin DAHMS Hans-Uwe DONG ChangYong CHEN YiFei HOU HaoChen YANG WanXi ZOU XiangYang | 2013 | Chinese Science Bulletin2013，58，19： | 3 |
| 5 | Taking the pulse of COVID-19:a spatiotemporal perspective显示文摘The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the U.S.The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and Brazil.In response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global citizens.This perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies. | Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou You Zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding | 2020 | International Journal of Digital Earth2020，13，10： | 2 |
| 6 | Biodegradable, Super-Strong, and Conductive Cellulose Macrofibers for Fabric-Based Triboelectric Nanogenerator显示文摘Electronic fibers used to fabricate wearable triboelectric nanogenerator(TENG) for harvesting human mechanical energy have been extensively explored. However, little attention is paid to their mutual advantages of environmental friendliness, mechanical properties, and stability. Here, we report a super-strong, biodegradable, and washable cellulose-based conductive macrofibers, which is prepared by wet-stretching and wet-twisting bacterial cellulose hydrogel incorporated with carbon nanotubes and polypyrrole. The cellulose-based conductive macrofibers possess high tensile strength of 449 MPa(able to lift 2 kg weights), good electrical conductivity(~ 5.32 S cm^(-1)), and excellent stability(Tensile strength and conductivity only decrease by 6.7% and 8.1% after immersing in water for 1 day). The degradation experiment demonstrates macrofibers can be degraded within 108 h in the cellulase solution. The designed fabric-based TENG from the cellulose-base conductive macrofibers shows a maximum open-circuit voltage of 170 V, short-circuit current of 0.8 μA, and output power at 352 μW, which is capable of powering the commercial electronics by charging the capacitors. More importantly, the fabric-based TENGs can be attached to the human body and work as self-powered sensors to effectively monitor human motions. This study suggests the potential of biodegradable, super-strong, and washable conductive cellulose-based fiber for designing eco-friendly fabric-based TENG for energy harvesting and biomechanical monitoring. | Sanming Hu Jing Han Zhijun Shi Kun Chen Nuo Xu Yifei Wang Ruizhu Zheng Yongzhen Tao Qijun Sun Zhong Lin Wang Guang Yang | 2022 | Nano-Micro Letters2022，14，7： | 2 |
| 7 | Unsourced Multiple Access for 6G Massive Machine Type Communications显示文摘Unsourced multiple access(UMA)is a multi-access technology for massive,low-power,uncoordinated,and unsourced Machine Type Communication(MTC)networks.It ensures transmission reliability under the premise of high energy efficiency.Based on the analysis of the 6G MTC key performance indicators(KPIs)and scenario characteristics,this paper summarizes its requirements for radio access networks.Following this,the existing multiple access models are analyzed under these standards to determine UMA's advantages for 6G MTC according to its design characteristics.The critical technology of UMA is the design of its multiple-access coding scheme.Therefore,the existing UMA coding schemes from different coding paradigms are further summarized and compared.In particular,this paper comprehensively considers the energy efficiency and computational complexity of these schemes,studies the changes of the above two indexes with the increase of access scale,and considers the trade-off between the two.It is revealed by the above analysis that some guiding rules of UMA coding design.Finally,the open problems and potentials in this field are given for future research. | Yuanjie Li Jincheng Dai Zhongwei Si Kai Niu Chao Dong Jiaru Lin Sen Wang Yifei Yuan | 2022 | China Communications2022，19，3： | 2 |
| 8 | Decimal Solvent-Based High-Entropy Electrolyte Enabling the Extended Survival Temperature of Lithium-Ion Batteries to−130°C显示文摘Freezing and crystallization of commercial ethylene carbonate-based binary electrolytes,leading to irreversible damage to lithium-ion batteries(LIBs),remain a significant challenge for the survival of energy storage devices at extremely low temperatures(<−40°C).Herein,a decimal solvent-based high-entropy electrolyte is developed with an unprecedented low freezing point of−130°C to significantly extend the service temperature range of LIBs,far superior to−30°C of the commercial counterpart.Distinguished from conventional electrolytes,this molecularly disordered solvent mixture greatly suppresses the freezing crystallization of electrolytes,providing good protection for LIBs from possible mechanical damage at extremely low temperatures.Benefiting from this,our high-entropy electrolyte exhibits extraordinarily high ionic conductivity of 0.62 mS·cm−1 at−60°C,several orders of magnitude higher than the frozen commercial electrolytes.Impressively,LIBs utilizing decimal electrolytes can be charged and discharged even at an ultra-low temperature of−60°C,maintaining high capacity retention(∼80%at−40°C)as well as remarkable rate capability.This study provides design strategies of low-temperature electrolytes to extend the service temperature range of LIBs,creating a new avenue for improving the survival and operation of various energy storage systems under extreme environmental conditions. | Wei Zhang Huarong Xia Zhiqiang Zhu Zhisheng Lv Shengkai Cao Jiaqi Wei Yifei Luo Yao Xiao Lin Liu Xiaodong Chen | 2021 | CCS Chemistry2021，3，4： | 2 |
| 9 | A ROS-responsive,self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction显示文摘Myocardial infarction(MI),as one of the leading causes of global death,urgently needs effective therapies.Recently,hydrogen sulfide(H2S)has been regarded as a promising therapeutic agent for MI,while its spatiotemporally controlled delivery remains a major issue limiting clinical translation.To address this limitation,we designed and synthesized a novel H2S donor(HSD-R)that can produce H2S and emit fluorescence in response to reactive oxygen species(ROS)highly expressed at diseased sites.HSD-R can specifically target mitochondria and provide red fluorescence to visualize and quantify H2S release in vitro and in vivo.Therapeutically,HSD-R significantly promoted the reconstruction of cardiac structure and function in a rat MI model.Mechanistically,myocardial protection is achieved by reducing cardiomyocyte apoptosis,attenuating local inflammation,and promoting angiogenesis.Furthermore,inhibition of typical pro-apoptotic genes(Bid,Apaf-1,and p53)played an important role in the anti-apoptotic effect of HSD-R to achieve cardioprotection,which were identified as new therapeutic targets of H2S against myocardial ischemia injury.This ROS-responsive,self-immolative,and fluorescent H2S donor can serve as a new theranostic agent for MI and other ischemic diseases. | Mengyun Yao Yifei Lu Lin Shi Yong Huang Qing Zhang Jianglin Tan Ping Hu Jianxiang Zhang Gaoxing Luo Ning Zhang | 2022 | Bioactive Materials2022，7，3： | 2 |
| 10 | Fingerprint image enhancement:algorithm and performance evaluation显示文摘 | Lin Hong Wan Yifei Jain A K | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 11 | Fingerprint image enhancement显示文摘 | Lin Hong Wan Yifei Jain A | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 12 | Niching clonal selection algorithm for multimodal function optimization显示文摘 | LIN Hao GONG Maoguo SUN Yifei | 2006 | Lecture Notes in Computer Science2006，4221，： | 1 |
| 13 | Emerging Iontronic Sensing: Materials, Mechanisms, and Applications显示文摘Iontronic sensors represent a novel class of soft electronics which not only replicate the biomimetic structures and perception functions of human skin but also simulate the mechanical sensing mechanism.Relying on the similar mechanism with skin perception,the iontronic sensors can achieve ion migration/redistribution in response to external stimuli,promising iontronic sensing to establish more intelligent sensing interface for human-robotic interaction.Here,a comprehensive review on advanced technologies and diversified applications for the exploitation of iontronic sensors toward ionic skins and artificial intelligence is provided.By virtue of the excellent stretchability,high transparency,ultrahigh sensitivity,and mechanical conformality,numerous attempts have been made to explore various novel ionic materials to fabricate iontronic sensors with skin-like perceptive properties,such as self-healing and multimodal sensing.Moreover,to achieve multifunctional artificial skins and intelligent devices,various mechanisms based on iontronics have been investigated to satisfy multiple functions and human interactive experiences.Benefiting from the unique material property,diverse sensing mechanisms,and elaborate device structure,iontronic sensors have demonstrated a variety of applications toward ionic skins and artificial intelligence. | Yao Xiongg Jing Han Yifei Wang Zhong Lin Wang Qijun Sun | 2022 | Research2022，，4： | 1 |
| 14 | Fingerprint image enhancement:algorithm and performance evaluation显示文摘 | Wan Yifei Jain A | 1998 | IEEE Trans on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 15 | Fingerprint Image Enhancement: Algorithm and Performence Evaluation显示文摘 | Lin Hong Wan Yifei Jain A | 1998 | IEEE Transaction on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 16 | Fingerprint Image Enhancement: Algorithm and Performance Evaluation 显示文摘 | Lin Hong Yifei Wan Anil Jain | 1998 | IEEE Transaction on Pattern Analysis and Machine Intelligence1998，8，20： | 1 |
| 17 | Fingerprint image enhancement: algorithm and performance evaluation 显示文摘 | Lin Hong Wan Yifei Jain A K | 1998 | IEEE Transactions on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 18 | Fingerprint image enhancement: algorithm and performance evaluation显示文摘 | Lin Hong Wan Yifei Anil Jain | 1998 | IEEE Transaction on Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 19 | Fingerprint Image Enhancement: Algorithm and Performance Evaluation显示文摘 | Lin Hong Yifei Wan Anil Jain | 1998 | Pattern Analysis and Machine Intelligence1998，20，8： | 1 |
| 20 | Sensitive and specific LC–MS/MS method for the simultaneous measurements of viramidine and ribavirin in human plasma显示文摘 | Yifei Liu Christine Xu Rongzi Yan Charmaine Lim Li-Tain Yeh Chin-chung Lin | 2006 | Journal of Chromatography B2006，，1： | 1 |
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