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    题名 作者 年代 出处 被引量
1Simulation on the dynamics of forest area changes in Northeast China显示文摘There is plenty of forests in Northeast China which contributes a lot to the conservation of water and land resources, produces timber products, and provides habitats for a huge number of wild animals and plants. With changes of socio-economic factors as well as the geophysical conditions, there are dramatic changes on the spatial patterns of forest area. In this sense, it is of great significance to shed light on the dynamics of forest area changes to find the underlining reasons for shaping the changing patterns of forest area in Northeast China. To explore the dynamics of forest area change in Northeast China, an econometric model is developed which is composed of three equations identifying forestry production, conversion from open forest to closed forest and conversion from other land uses to closed forest so as to explore the impacts on the forest area changes from demographic, social, economic, location and geophysical factors. On this basis, we employ the Dynamics of Land System (DLS) model to simulate land-use conversions between forest area and non-forest cover and the land-use conversions within the sub-classes of forest area for the period 2000–2020 under business as usual scenario, environmental protection scenario and economic growth scenario. The simulation results show that forest area will expand continuously and there exist various kinds of changing patterns for the sub-classes of forest area, for example, closed forest will expand continuously and open forest and shrub will decrease a little bit, while area of other forest will keep intact. The research results provide meaningful decision-making information for conserving and exploiting the forest resources and making out the planning for forestry production in the Northeast China region.DENG Xiangzheng JIANG Qun'ou ZHAN Jinyan HE Shujin LIN Yingzhi 2010Journal of Geographical Sciences2010,20,4:11
2Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemiareperfusion injury in aged rats显示文摘Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia, and the role is mediated by the expression of mitochondrial proteins. This study investigated the involvement of mitochondrial proteins in hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats using a comparative proteomics strategy. Our experimental results show that the aged rat brain is sensitive to ischemia-reperfusion injury and that transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats. Differential proteomics analysis suggested that this phenomenon may be mediated by mitochondrial proteins associated with energy metabolism and apoptosis in aged rats. This study provides potential drug targets for the treatment of transient cerebral ischemia-reperfusion injury.Xiangyu Ji Li'na Zhang Ran Liu Yingzhi Liu Jianfang Song He Dong Yanfang Jia Zangong Zhou 2014Neural Regeneration Research2014,9,11:9
3Comparison of multinomial logistic regression and logistic regression: which is more efficient in allocating land use?显示文摘陆地使用变化的空间地明确的模拟是在精力流动,生态学和环境上估计陆地使用和盖子变化的效果的基础。在象素水平,逻辑回归是在分配建模决定在陆地使用之间的关系的空间地明确的陆地使用使用的最普通的途径之一,它在开车的原因的因素打使用变化,并且从而使用适用性评估土地。然而,这些模型有一个缺点因为他们不基于在陆地使用变化和它的开车因素之间的直接关系决定 / 分配陆地使用。因而,一个多项的逻辑回归方法被介绍探讨这个缺陷,并且从而,在江西省的一个案例研究区域在任何给定的象素判定陆地使用的一种类型的适用性,中国。二个回归方法的比较比用逻辑回归获得了的显示用多项的逻辑回归的正确地分配的象素的比例是 92.98% ,它高是 8.47% 。配对的 t 测试结果也证明象素被多项的逻辑回归更清楚地比由逻辑回归区分。在结论,多项的逻辑回归是为陆地使用变化的空间分配的一个更有效、精确的方法。在未来陆地使用变化研究的这个方法的申请可以改进在精力流动,生态学,和环境上预言陆地使用和盖子变化的效果的精确性。Yingzhi LIN Xiangzheng DENG Xing LI Enjun MA 2014Frontiers of Earth Science2014,8,4:9
4Development of database of real-world diesel vehicle emission factors for China显示文摘A database of real-world diesel vehicle emission factors, based on type and technology, has been developed following tests on more than 300 diesel vehicles in China using a portable emission measurement system. The database provides better understanding of diesel vehicle emissions under actual driving conditions. We found that although new regulations have reduced real-world emission levels of diesel trucks and buses significantly for most pollutants in China, NOx emissions have been inadequately controlled by the current standards, especially for diesel buses, because of bad driving conditions in the real world. We also compared the emission factors in the database with those calculated by emission factor models and used in inventory studies. The emission factors derived from COPERT(Computer Programmer to calculate Emissions from Road Transport) and MOBILE may both underestimate real emission factors, whereas the updated COPERT and PART5(Highway Vehicle Particulate Emission Modeling Software) models may overestimate emission factors in China. Real-world measurement results and emission factors used in recent emission inventory studies are inconsistent,which has led to inaccurate estimates of emissions from diesel trucks and buses over recent years. This suggests that emission factors derived from European or US-based models will not truly represent real-world emissions in China. Therefore, it is useful and necessary to conduct systematic real-world measurements of vehicle emissions in China in order to obtain the optimum inputs for emission inventory models.Xianbao Shen Zhiliang Yao Qiang Zhang David Vance Wagner Hong Huo Yingzhi Zhang Bo Zheng Kebin He 2015Journal of Environmental Sciences2015,27,5:8
5The Dynamics of a Predator-prey Model with Ivlev's Functional Response Concerning Integrated Pest Management显示文摘A mathematical model of a predator-prey model with Ivlev's functional response concerning integrated pest management (IPM) is proposed and analyzed. We show that there exists a stable pest-eradication periodic solution when the impulsive period is less than some critical values, Further more, the conditions for the permanence of the system are giverl. By using bifurcation theory, we show the existence and stability of a positive periodic solution. These results are quite different from those of the corresponding system without impulses. Numerical simulation shows that the system we consider has more complex dynamical behaviors.Finally, it is proved that IPM stragey is more effective than the classical one.BingLiu YingZhi Lan-sunChen 2004Acta Mathematicae Applicatae Sinica2004,20,1:8
6Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation显示文摘Nanotechnology-based photothermal therapy has attracted great attention in the past decade. Nevertheless, photothermal therapy has some inherent drawbacks, such as the uneven heat production and limited laser penetration, often leading to insufficient treatment outcomes. Here, we developed a combination strategy to improve cancer therapy. The biomimetic albumin-modified gold nanorods(AuNRs) were prepared with incorporation of paclitaxel(PTX). This therapeutic system was characterized by several features. First, the albumin modification enhanced the biocompatibility and colloidal stability. Second, the surface-coated albumin promoted cellular uptake via the albumin-binding protein pathway. Third, PTX was incorporated via hydrophobic interaction between PTX and the albumin lipophilic domain. Fourth, the system can be used for combined photothermo-chemotherapy for yielding synergistic effects. The antitumor activity of the system was evaluated both in vitro and in vivo using the HCT116 colon cancer cell and tumor model. The combination therapy was found with an enhanced treatment efficiency and no obvious side effect. Most importantly, the thermal effect was also discovered with the ability to modulate the tumor microenvironments and suppress the macrophages polarization towards the M2 pro-tumor phenotype. It could be a mechanism for photothermal immunotherapy. The combination strategy and the system provide a potential method for cancer therapy.Dongdong Li Meng Zhang Fan Xu Yingzhi Chen Binfan Chen Ya Chang Huihai Zhong Hongyue Jin Yongzhuo Huang 2018Acta Pharmaceutica Sinica B2018,8,1:8
7Facile synthesis of bimodal macroporous g-C_3N_4/SnO_2 nanohybrids with enhanced photocatalytic activity显示文摘It is of vital importance to construct highly interconnected,macroporous photocatalyst to improve its efficiency and applicability in solar energy conversion and environment remediation.Graphitic-like C_3N_4(g-C_3N_4),as an analogy to two-dimensional(2D)graphene,is highly identified as a visible-lightresponsive polymeric semiconductor.Moreover,the feasibility of g-C_3N_4 in making porous structures has been well established.However,the preparation of macroporous g-C_3N_4 with abundant porous networks and exposure surface,still constitutes a difficulty.To solve it,we report a first facile preparation of bimodal macroporous g-C_3N_4 hybrids with abundant in-plane holes,which is simply enabled by in-situ modification through thermally treating the mixture of thiourea and SnCl_4(pore modifier)after rotary evaporation.For one hand,the formed in-plane macropores endow the g-C_3N_4 system with plentiful active sites and short,cross-plane diffusion channels that can greatly speed up mass transport and transfer.For another,the heterojunctions founded between g-C_3N_4 and SnO_2 consolidate the electron transfer reaction to greatly reduce the recombination probability.As a consequence,the resulted macroporous gC_3N_4/SnO_2 nanohybrid had a high specific surface area(SSA)of 44.3 m^2/g that was quite comparable to most nano/mesoporous g-C_3N_4 reported.The interconnected porous network also rendered a highly intensified light absorption by strengthening the light penetration.Together with the improved mass transport and electron transfer,the macroporous g-C_3N_4/SnO_2 hybrid exhibited about 2.4-fold increment in the photoactivity compared with pure g-C_3N_4.Additionally,the recyclability of such hybrid could be guaranteed after eight successive uses.Yingzhi Chen Wenhao Li Dongjian Jiang Kuo Men Zhen Li Ling Li Shizheng Sun Jingyuan Li Zheng-Hong Huang Lu-Ning Wang 2019Science Bulletin2019,64,1:7
8Wide-steering-angle high-resolution optical phased array显示文摘Optical phased array(OPA)technology is considered a promising solution for solid-state beam steering to supersede the traditional mechanical beam steering.As a key component of the LIDAR system for long-range detection,OPAs featuring a wide steering angle and high resolution without beam aliasing are highly desired.However,a wide steering range requires a waveguide pitch less than half of the wavelength,which is easily subjected to cross talk.Besides,high resolution requires a large aperture,and it is normally achieved by a high count number of waveguides,which complicates the control system.To solve the mentioned issues,we design two high-performance 128-channel OPAs fabricated on a multilayered SiN-on-SOI platform.Attributed to the nonuniform antenna pitch,only 128 waveguides are used to achieve a 4 mm wide aperture.Besides,by virtue of innovative dual-level silicon nitride(Si_(3)N_(4))waveguide grating antennas,the fishbone antenna OPA achieves a 100°×19.4°field of view(FOV)with divergence of 0.021°×0.029°,and the chain antenna OPA realizes a 140°×19.23°FOV with divergence of 0.021°×0.1°.To our best knowledge,140°is the widest lateral steering range in two-dimensional OPA,and 0.029°is the smallest longitudinal divergence.Finally,we embed the OPA into a frequency-modulated continuous-wave system to achieve 100 m distance measurement.The reflected signal from 100 m distance is well detected with 26 dBm input transmitter power,which proves that OPA serves as a promising candidate for transceiving optical signal in a LIDAR system.YINGZHI LI BAISONG CHEN QUANXIN NA QIJIE XIE MIN TAO LANXUAN ZHANG ZIHAO ZHI YUXUAN LI XIAOBIN LIU XIANSHU LUO GUOQIANG LO FENGLI GAO XUEYAN LI JUNFENG SONG 2021Photonics Research2021,9,12:7
9Novel circular RNA expression profile of uveal melanoma revealed by microarray显示文摘Objective: The present study aimed to investigate circular RNA(circRNA) expression in uveal melanoma(UM).Methods: First,we used microarray to compare the expression profiles of circRNA in five UM samples and five normal uvea tissues.Next,bioinformatics analyses,including gene ontology(GO) analysis and pathway analysis,were applied to study these differentially expressed circRNAs to predict pathogenic pathways that may be involved.Quantitative real-time polymerase chain reaction(qRT-PCR) in 20 UM samples and 20 normal uvea samples was used to confirm the circRNA expression profiles obtained from the microarray data.Finally,we analyzed the interaction between validated circRNAs and their potential cancer-associated miRNA targets.Results: In total,50,579 circRNAs [fold change(FC) ≥2.0; P<0.05],including 20,654 up-regulated and 29,925 down-regulated circRNAs,were identified as differentially expressed between UM tissues and normal uvea tissues.We used qRT-PCR to verify seven dysregulated circRNAs indicated by the microarray data,including hsa_circ_0119873,hsa_circ_0128533,hsa_circ_0047924,hsa_circ_0103232,hsa-circRNA10628-6,hsa_circ_0032148 and hsa_circ_0133460,which may be promising candidates to study future molecular mechanisms.Conclusions: This study explored,for the first time,the abnormal expression of circRNAs in UM and described the expression profile of circRNAs,providing a new potential target for the mechanism of UM and future treatment of UM.Xuan Yang Yang Li Yueming Liu Xiaolin Xu Yingzhi Wang Yanni Yan Wenjia Zhou Jingyan Yang Wenbin Wei 2018Chinese Journal of Cancer Research2018,30,6:6
10Design of Environmental Monitoring and Control System for Large-scale Pig House with Fermentation Bed显示文摘The design and assembly of environmental monitoring and control system for large-scale pig house with fermentation bed helped to solve the problem of environmental automatic control in piggery.The sensors would monitor the temperature,humidity,light,wind direction,wind speed,CO2,NH3and other parameters.On-line real-time data collection was achieved.The expert system was constructed to control the temperature in piggery below 30℃,to control the air and mattress humidities higher than 65%.Under the conditions of different season or different wind speed,even in day and night,the control actuators were different.The actuators included fanning wet curtain,lighting,micro spraying,spraying,propeller fan,electric aluminum alloy shutter and spraying systems on the roof.The actuators were integrated,and they control the piggery environment simultaneously.The system also designed the remote video monitor interface,parameter-monitoring curved interface and operation interface,which provided a good man-machine interface.Bo LIU Huiyong ZHENG Yingzhi LIN Shengbing LIU Hongyi ZHENG Chunzhong YOU Huai SHI Jianglin LAN Zhaolong LI Jianyang TANG Qinlou HUANG 2015Agricultural Science & Technology2015,16,2:6
11Legislation on protection of drinking water sources and local management practices in the Pearl River Delta region of China显示文摘The protection of drinking water sources is vital to urban development and public health.In this study,the current situation of the mandatory protection area for drinking water source in the Pearl River Delta region was investigated using a method combining Google Earth with the field survey.The gaps between management practices and legislation requirements were analyzed.Finally,several countermeasures for water resource protection were proposed as follows:to promote delineation in a more scientific way,to safeguard the sanctity of the law,to make better plan on water saving,and to encourage public participation in supervision and management.Zhigang Wang Yang Liu Yingzhi Li Peng Zhao Jiangyu Yu 2016Chinese Journal of Population,Resources and Environment2016,16,2:6
12Single-cell RNA-seq reveals the immune escape and drug resistance mechanisms of mantle cell lymphoma显示文摘Objective:Mantle cell lymphoma(MCL)is a rare subtype of non-Hodgkin lymphoma(NHL)with high heterogeneity and a high recurrence rate.How heterogenous cell populations contribute to relapse remains to be elucidated.Methods:We performed single cell RNA sequencing(scRNA-seq)on approximately 4,000 bone marrow cells sampled from one patient with multidrug resistant MCL.We identified 10 subpopulations comprising 4 malignant B cell subtypes,3 T cell subtypes,2 dendritic cell subtypes and 1 natural killer(NK)cell subtype.Subsequently,we identified cell markers,including a series of genes associated with immune escape and drug resistance.In addition,we explored the roles of these genes in the mechanism of immune escape and drug resistance,and we verified the expression imbalance and clinical prognostic potential by using GEO datasets including 211 MCL samples.Results:The major immune escape mechanisms of MCL included anti-perforin activity,decreased immunogenicity and direct inhibition of apoptosis and cell killing,as mediated by type I and II B cells.The drug resistance mechanisms of different cell clusters included drug metabolism,DNA damage repair,apoptosis and survival promotion.Type III B cells closely communicate with other cells.The key genes involved in the resistance mechanisms showed dysregulated expression and may have significant clinical prognostic value.Conclusion:This study investigated potential immune escape and drug resistance mechanisms in MCL.The results may guide individualized treatment and promote the development of therapeutic drugs.Liang Wang Steven Mo Xin Li Yingzhi He Jing Yang 2020Cancer Biology & Medicine2020,17,3:5
13Determination of DNA single-strand breaks by low-energy heavy ion and analysis of dose-effect curves显示文摘Calf thymus DNA was exposed to low-energy heavy ions (N+) and 60Co-γ-rays, and the dose-effect on DNA single-strand breaks (SSB) has been investigated. The results indicate that the dose-effect curve by N+ irradiation is different from that of conventional ionizing radiation. While the curve from γ-irradiation follows exponential type, the effect curve produced by N+ ion is of 'saddle type'. The yield of DNASSB per dose unit per DNA unit remained at a certain level under different doses of γ-rays. In contrast, the DNASSB at low dosage region of N+ showed an obvious peak before it decreased rapidly to a lower level.Yanhua Du Shenghai Huang Zheng Tan Yingzhi Lin Guanying Qiu 1999Chinese Science Bulletin1999,44,8:5
14Two-dimensional vermiculite separator for lithium sulfur batteries显示文摘Lithium-sulfur batteries have been considered as one of the most promising battery system for their high theoretical energy density. However, the lithium-sulfur batteries suffer from the dissolution and diffusion of polysulfides, which induce parasitic reactions with lithium metal anodes. The safety of lithium-sulfur batteries is also concerned with the risk of dendrite growth on lithium metal anodes. To simultaneously address the challenges in the shuttle effect and safety problems, we demonstrate herein a two-dimensional vermiculite separator. With the assembly of the 2 D exfoliated vermiculite sheets, the vermiculite separator can suppress the diffusion of polysulfides across the separator through electrostatic interaction and steric hindrance. Meanwhile, the inorganic sheets with high strength and Young's modulus prevent the penetration of lithium metal dendrite and potentially improve the safety of the system. This work elucidates a promising strategy for safe and stable lithium sulfur batteries,and can also be extended to other electrochemical systems based on metal anodes.Rui Xu Yingzhi Sun Yunfei Wang Jiaqi Huang Qiang Zhang 2017Chinese Chemical Letters2017,28,12:5
15An equilibrium analysis of the land use structure in the Yunnan Province, China显示文摘全球陆地使用结构由于不停的人口生长很快正在变化并且加速都市化,它导致在对的僵硬要求之间的凶猛的竞争布满建筑物区域和栽培土地,森林,和草地的保护。认识到陆地资源的持续发展是大挑战。与社会财务矩阵数据集基于陆地使用变化的一个可计算出来的一般平衡模型,这研究在三种情形下面在 20082020 的时期期间在云南省实现了陆地使用结构的平衡分析,基线情形,低 TFP (全部的因素生产率)情形,并且高 TFP 情形。结果显示在所有三种情形下面,栽培土地的区域与显著扩大一起显著地衰退了布满建筑物区域当森林,草地,和闲置的土地的区域稍微增加了时。TFP 的生长率在扩大上有第一否定然后积极的效果布满建筑物它增加了的栽培土地的区域和衰落。而且,栽培的两个的模仿的变化登陆并且布满建筑物区域在低 TFP 情形下面是最大的,并且远在 2020 在云南省为陆地利用在全面计划超过了限制。基于情形的模拟结果具有为在让土地使用决定的决策者的重要引用价值,平衡在栽培土地和增加的需求为的保护之间的凶猛的比赛布满建筑物区域,和保证食物安全,生态的安全,和陆地资源的持续开发。Jiao LUO Jinyan ZHAN Yingzhi LIN Chunhong ZHAO 2014Frontiers of Earth Science2014,8,3:5
16Characterization of event-related potentials in obsessive compulsive disorder patients: Comparison with depression and generalized anxiety disorder patients显示文摘BACKGROUND: Study results of event-related potential in obsessive compulsive disorder (OCD) remain controversial, potentially as a result of different instruments utilized and their differing technical characteristics. OBJECTIVE: To investigate the differences in several common event-related potentials, i.e. contingent negative variations, P300, and mismatch negativity (MMN), in OCD patients, depression patients, generalized anxiety disorder (GAD) patients, and healthy controls. DESIGN, TIME AND SETTING: A case-control study was performed in the Department of Electrophysiology, Shanghai Mental Health Center from May 2002 to December 2005. PARTICIPANTS: A total of 38 OCD patients, 20 depression patients, and 18 GAD patients, who were diagnosed according to the criteria of Chinese Classification of Mental Disorders (Version 3), formulated by the Chinese Psychiatry Association, were selected from the Outpatient Department o Shanghai Mental Health Center. Patients with two or more the above diseases were excluded. In addition, 28 healthy people, gender and age matched, were selected as controls. METHODS: Contingent negative variations, P300, and MMN were recorded by a Nicolet Spirit Instrument. All electrodes were attached at Cz according to the International 10-20 system, with the mastoid leads as reference and Fpz as ground. MAIN OUTCOME MEASURES: Amplitude and latency of contingent negative variations, P300, and MMN. RESULTS: The contingent negative variations, P300, and MMN were different (P < 0.01). OCD patients showed an increased M1 amplitude compared with controls, depression, and GAD patients (P < 0.01). Target P300 amplitudes were significantly lower in OCD, depression, and GAD patients compared with controls (P < 0.01). Moreover, N2 latency and latency of MMN were prolonged in OCD and depression groups compared with controls (P < 0.05). CONCLUSION: Event-related potentials were different in depression, GAD, and OCD patients and healthy controls. In particular, OCD patients exhibited unique characteristics.Yingzhi Lu Wenbin Zong Hanzhen Dong Faxin Wang Jinyu PU Xingshi Chen Yunxiang Tang 2010Neural Regeneration Research2010,5,12:5
17Facile fabrication of three-dimensional interconnected nanoporous N-TiO_2 for efficient photoelectrochemical water splitting显示文摘Three-dimensional(3 D) interconnected porous architectures are expected to perform well in photoelectrochemical(PEC) water splitting due to their high specific surface area as well as favourable porous properties and interconnections. In this work, we demonstrated the facile fabrication of 3 D interconnected nanoporous N-doped TiO_2(N-TiO_2 network) by annealing the anodized 3 D interconnected nanoporous TiO_2(TiO_2 network) in ammonia atmosphere. The obtained N-TiO_2 network exhibited broadened light absorption, and abundant, interconnected pores for improving charge separation, which was supported by the reduced charge transfer resistance. With these merits, a remarkably high photocurrent density at 1.23 V vs. reversible hydrogen electrode(RHE) was realized for the N-TiO_2 network without any co-catalysts or sacrificial reagents, and the photostability can be assured after long term illumination.In view of its simplicity and efficiency, this structure promises for perspective PEC applications.Yingzhi Chen Aoxiang Li Qun Li Xinmei Hou Lu-Ning Wang Zheng-Hong Huang 2018Journal of Materials Science & Technology2018,34,6:4
18Stress Effect of Cadmium Absorption between Aloe and Solanum nigrum L显示文摘The stress effect of cadmium absorption between aloe and Solanum nigrum L was studied through a simulation experiment with different cadmium contents in soil.The results showed that the growth characteristics,biomass and Cd content in the plants of aloe and S.nigrum L were closely related to Cd content in the soil,and S.nigrum L and aloe had a strong tolerance to Cd in the experiment.pH of rhizosphere soil with S.nigrum L and aloe planted was generally higher than that of non-rhizosphere soil,which is related to the planting pattern.Compared with aloe,S.nigrum L had a stronger capacity to accumulate Cd,and intercropping S.nigrum L and aloe could inhibit aloe's absorption of Cd,which is favorable to the safe planting of aloe.In addition,S.nigrum L has the potential to restore polluted soil.Chen Yingzhi Fu Shanming Wang Jianhuang Pei Jie Li Wenhao He Caizhen 2015Meteorological and Environmental Research2015,6,3:4
19Factors and mechanism driving the land-use conversion in Jiangxi Province显示文摘This article explores the factors and mechanism driving the land-use conversion at regional level by developing and using an econometric approach which is called the simultaneous equations model (SEM). A case study in Jiangxi Province of China is conducted by establishing the SEM, which consists of three equations including agricultural production, land conversion of cultivated land to built-up area and land conversion of cultivated land to forest cover/grassland from 1988 to 2005. And then this paper employs the method of piecewise estimation to represent the influences of the factors such as population, society, economy, location and geophysical conditions on the process of land-use conversion in Jiangxi Province. Estimation results show that population is a predominant factor driving the land-use conversion at counties, while social and economic factors are determinant factors in the short term for the entire Jiangxi Province. Specifically, the size of agricultural population and the magnitude of agricultural input determine the agricultural production to a large extent; population size, plain area proportion at counties and land management policies together affect the direction and magnitude of conversion between cultivated land and built-up area; agricultural population proportion, terrain slope, grain production and non-agricultural industry promote the conversion of cultivated land to forest cover/grassland. Furthermore, the explored mechanism also reveals the underlying causes of the land use changes driven by a series of factors in Jiangxi Province. Finally, this paper concludes that factors proven to play an important role in driving the land-use conversion need to be considered when the land management agencies make out the land use planning to optimize the land use, expand the agricultural production, and conserve the cultivated land.ZHAN Jinyan SHI Nana HE Shujin LIN Yingzhi 2010Journal of Geographical Sciences2010,20,4:4
20The influence of hyaluronic acid on vascular endothelial cell proliferation and the relationship with ezrin/merlin expression显示文摘它被建立了那玻尿的酸(哈) glycans (nHA ) 和 oligosaccharide (oHA ) 在脉管的 endothelial 房间(EC ) 的生物功能上施加不同效果,导致 angiogenesis 的改变的规定。然而,特定的机制仍然是不清楚的。我们的学习在 EC 在 ezrin 和灰背隼蛋白质上集中了于 nHA 和 oHA 的效果。ezrin 和灰背隼的表示在 EC 生长以及 mRNA 表示上是由 siRNA,和规定的 silenced, ezrin 和灰背隼的激活(phosphorylation ) 由 oHA 刺激了, nHA 被调查。结果表明当与 nHA 对待时,在 ezrin 表示或激活没有重要变化。在与 oHA 被对待以后,而在灰背隼表示没有明显的变化, ezrin 的表示和激活决定性地被增加(包括它的 phosphorylation ) 。与 ezrin 表示 silenced,象它的 phosphorylation 一样的灰背隼的表示在刺激 nHA 的人的脐的静脉 endothelial 房间铺平显著地被提高,当没有重要变化, oHA 导致时。与灰背隼表示 silenced,没有明显的变化在 ezrin 的表示被发现(包括它的 phosphorylation ) 由 nHA 导致了。相反地, ezrin 的表示和它的激活显著地在与 oHA 被对待以后被改进。结果建议为由 oHA 的 EC 增长的提升的机制与 ezrin 的表示和激活有关是可能的,并且由 nHA 的 EC 增长的抑制与灰背隼的表示和激活有关是可能的。Wei Mo Cuixia Yang Yiwen Liu Yiqing He Yingzhi Wang Feng Gao 2011Acta Biochimica et Biophysica Sinica2011,43,12:3
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