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1Towards 6G wireless communication networks:vision,enabling technologies,and new paradigm shifts显示文摘The fifth generation(5G)wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized,such as mass connectivity,ultra-reliability,and guaranteed low latency.However,5G will not meet all requirements of the future in 2030 and beyond,and sixth generation(6G)wireless communication networks are expected to provide global coverage,enhanced spectral/energy/cost efficiency,better intelligence level and security,etc.To meet these requirements,6G networks will rely on new enabling technologies,i.e.,air interface and transmission technologies and novel network architecture,such as waveform design,multiple access,channel coding schemes,multi-antenna technologies,network slicing,cell-free architecture,and cloud/fog/edge computing.Our vision on 6G is that it will have four new paradigm shifts.First,to satisfy the requirement of global coverage,6G will not be limited to terrestrial communication networks,which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle(UAV)communication networks,thus achieving a space-airground-sea integrated communication network.Second,all spectra will be fully explored to further increase data rates and connection density,including the sub-6GHz,millimeter wave(mmWave),terahertz(THz),and optical frequency bands.Third,facing the big datasets generated by the use of extremely heterogeneous networks,diverse communication scenarios,large numbers of antennas,wide bandwidths,and new service requirements,6G networks will enable a new range of smart applications with the aid of artificial intelligence(AI)and big data technologies.Fourth,network security will have to be strengthened when developing 6G networks.This article provides a comprehensive survey of recent advances and future trends in these four aspects.Clearly,6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears.Xiaohu YOU Cheng-Xiang WANG Jie HUANG Xiqi GAO Zaichen ZHANG Mao WANG Yongming HUANG Chuan ZHANG Yanxiang JIANG Jiaheng WANG Min ZHU Bin SHENG Dongming WANG Zhiwen PAN Pengcheng ZHU Yang YANG Zening LIU Ping ZHANG Xiaofeng TAO Shaoqian LI Zhi CHEN Xinying MA Chih-Lin I Shuangfeng HAN Ke LI Chengkang PAN Zhimin ZHENG Lajos HANZO Xuemin(Sherman)SHEN Yingjie Jay GUO Zhiguo DING Harald HAAS Wen TONG Peiying ZHU Ganghua YANG Jun WANG Erik GLARSSON Hien Quoc NGO Wei HONG Haiming WANG Debin HOU Jixin CHEN Zhe CHEN Zhangcheng HAO Geoffrey Ye LI Rahim TAFAZOLLI Yue GAO HVincent POOR Gerhard P.FETTWEIS Ying-Chang LIANG 2021Science China(Information Sciences)2021,64,1:122
2aunalysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza显示文摘Haibin Xu Jingyuan Song Hongmei Luo Yujun Zhang Qiushi Li Yingjie Zhu Jiang Xu Ying Li Chi Song Bo Wang Wei Sun Guoan Shen Xin Zhang Jun Qian Aijia Ji Zhichao Xu Xiang Luo Liu He Chuyuan Li Chao Sun Haixia Yah Guanghong Cui Xiwen Li Xian 'en Li Jianhe Wei Juyan Liu Yitao Wang Alice Hayward David Nelson Zemin Ning Reuben J. Peters Xiaoquan Qi Shilin Chen 2016Molecular Plant2016,9,6:70
3Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients显示文摘Pathogenic human coronavirus infections,such as severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERS-CoV),cause high morbidity and mortality[1,2].Recently,a severe pneumonia-associated respiratory syndrome caused by a new coronavirus(SARS-CoV-2)was reported in December 2019 in the city of Wuhan,Hubei province,China[3-5],which was also named as pneumonia-associated respiratory syndrome(PARS)[6]and can cause coronavirus disease 2019(COVID-19)to seriously endanger human health.Yonggang Zhou Binqing Fu Xiaohu Zheng Dongsheng Wang Changcheng Zhao Yingjie Qi Rui Sun Zhigang Tian Xiaoling Xu Haiming Wei 2020National Science Review2020,7,6:54
4Crustal structure of the northeastern Tibetan plateau,the Ordos block and the Sichuan basin from ambient noise tomography显示文摘We apply ambient noise tomography to significant seismic data resources in a region including the northeastern Tibetan plateau,the Ordos block and the Sichuan basin.The seismic data come from about 160 stations of the provincial broadband digital seismograph networks of China.Ambient noise cross-correlations are performed on the data recorded between 2007 and 2009 and high quality inter-station Rayleigh phase velocity dispersion curves are obtained between periods of 6 s to 35 s.Resulting Rayleigh wave phase velocity maps possess a lateral resolution between 100 km and 200 km.The phase velocities at short periods (<20 s) are lower in the Sichuan basin,the northwest segment of the Ordos block and the Weihe graben,and outline sedimentary deposits.At intermediate and long periods (>25 s),strong high velocity anomalies are observed within the Ordos block and the Sichuan basin and low phase velocities are imaged in the northeastern Tibetan plateau,reflecting the variation of crustal thickness from the Tibetan plateau to the neighboring regions in the east.Crustal and uppermost mantle shear wave velocities vary strongly between the Tibetan plateau,the Sichuan basin and the Ordos block.The Ordos block and the Sichuan basin are dominated by high shear wave velocities in the crust and uppermost mantle.There is a triangle-shaped low velocity zone located in the northeastern Tibetan plateau,whose width narrows towards the eastern margin of the plateau.No low velocity zone is apparent beneath the Qinling orogen,suggesting that mass may not be able to flow eastward through the boundary between the Ordos block and the Sichuan basin in the crust and uppermost mantle.Yong Zheng Yingjie Yang Michael H. Ritzwoller Xiufen Zheng Xiong Xiong Zuning Li 2010Earthquake Science2010,23,5:43
5芦山与汶川地震震区地壳上地幔结构及深部孕震环境显示文摘雅安芦山Mw6.6级地震,是汶川7.9级地震之后龙门山地区的又一次强震,给当地的社会经济发展和生态环境带来了巨大的破坏.本文借助全国地震台网连续波形数据,使用背景噪声层析成像方法和远震接收函数分析方法,获得了震区及其周边地区精细的S波速度结构和地壳厚度、泊松比分布情况,进而分析了龙门山断裂带及邻区深部孕震环境.研究结果发现:(1)龙门山断裂带两侧剪切波速度和地壳厚度有非常显著的差异;(2)芦山和汶川地震均位于地壳厚度和波速结构变化剧烈之处,断层的破裂面和余震的分布均处于地震波横向速度梯度和地壳厚度的横向梯度跳变的地区;地震深度处于从均匀波速结构向非均匀波速结构过渡区域;(3)汶川地震及其余震发生在泊松比较低的地区,而芦山地震及其余震发生在高泊松比的地区.我们推测,横向的显著速度变化,以及地壳厚度和地形高度的巨大差异所产生的重力势能等作用可能在一定程度上构造成了龙门山断裂系上大地震的孕震环境,而龙门山断裂带南北段岩石泊松比的差别,可能是导致汶川地震余震空间分布和芦山地震延后5年发生的原因.郑勇 葛粲 谢祖军 YingJie YANG 熊熊 许厚泽 2013中国科学:地球科学2013,43,6:40
6Crustal and upper mantle structure and the deep seismogenic environment in the source regions of the Lushan earthquake and the Wenchuan earthquake显示文摘Following the M w 7.9 Wenchuan earthquake, the M w 6.6 Lushan earthquake is another devastating earthquake that struck the Longmenshan Fault Zone (LFZ) and caused severe damages. In this study, we collected continuous broadband ambient noise seismic data and earthquake event data from Chinese provincial digital seismic network, and then utilized ambient noise tomography method and receiver function method to obtain high resolution shear wave velocity structure, crustal thickness, and Poisson ratio in the earthquake source region and its surroundings. Based on the tomography images and the receiver function results, we further analyzed the deep seismogenic environment of the LFZ and its neighborhood. We reveal three main findings: (1) There is big contrast of the shear wave velocities across the LFZ. (2) Both the Lushan earthquake and the Wenchuan earthquake occurred in the regions where crustal shear wave velocity and crustal thickness change dramatically. The rupture faults and the aftershock zones are also concentrated in the areas where the lateral gradients of crustal seismic wave speed and crustal thickness change significantly, and the focal depths of the earthquakes are concentrated in the transitional depths where shear wave velocities change dramatically from laterally uniform to laterally non-uniform. (3) The Wenchuan earthquake and its aftershocks occurred in low Poisson ratio region, while the Lushan earthquake sequences are located in high Poisson ratio zone. We proposed that the effect of the dramatic lateral variation of shear wave velocity, and the gravity potential energy differences caused by the big contrast in the topography and the crustal thickness across the LFZ may constitute the seismogenic environment for the strong earthquakes in the LFZ, and the Poisson ratio difference between the rocks in the south and north segments of the Longmenshan Fault zone may explain the 5 years delay of the occurrence of the Lushan earthquake than the Wenchuan earthquake.ZHENG Yong GE Can XIE ZuJun YANG YingJie XIONG Xiong HSU HouTze 2013Science China Earth Sciences2013,56,7:37
7Three dimensional shear wave velocity structure of the crust and upper mantle beneath China from ambient noise surface wave tomography显示文摘We determine the three-dimensional shear wave velocity structure of the crust and upper mantle in China using Green's functions obtained from seismic ambient noise cross-correlation.The data we use are from the China National Seismic Network,global and regional networks and PASSCAL stations in the region.We first acquire cross-correlation seismograms between all possible station pairs.We then measure the Rayleigh wave group and phase dispersion curves using a frequency-time analysis method from 8 s to 60 s.After that,Rayleigh wave group and phase velocity dispersion maps on 1° by 1° spatial grids are obtained at different periods.Finally,we invert these maps for the 3-D shear wave velocity structure of the crust and upper mantle beneath China at each grid node.The inversion results show large-scale structures that correlate well with surface geology.Near the surface,velocities in major basins are anomalously slow,consistent with the thick sediments.East-west contrasts are striking in Moho depth.There is also a fast mid-to-lower crust and mantle lithosphere beneath the major basins surrounding the Tibetan plateau (TP) and Tianshan (Junggar,Tarim,Ordos,and Sichuan).These strong blocks,therefore,appear to play an important role in confining the deformation of the TP and constraining its geometry to form its current triangular shape.In northwest TP in Qiangtang,slow anomalies extend from the crust to the mantle lithosphere.Meanwhile,widespread,a prominent low-velocity zone is observed in the middle crust beneath most of the central,eastern and southeastern Tibetan plateau,consistent with a weak (and perhaps mobile) middle crust.Xinlei Sun Xiaodong Song Sihua Zheng Yingjie Yang Michael H. Ritzwoller 2010Earthquake Science2010,23,5:28
8Research of the Unity Theory Between Three-level Space Vector and Carrier-based PWM Modulation Strategy显示文摘两电平空间矢量脉宽调制(space vector pulse widthmodulation,SVPWM)与正弦脉宽调制(sinusoidal pulse widthmodulation,SPWM)存有一定的本质关系,对于三电平,在常见的8段式SVPWM序列中可以证明,SVPWM与SPWM本质上也存在某种统一。实际的SVPWM调制中,由于要考虑中点电压平衡、减少谐波等其它性能问题,一般会利用开关冗余状态得到8段以上的开关调制序列。目前的文献中还未曾有对这些情况进行统一性地验证,因此三电平SVPWM与SPWM的统一理论存在一定的不足。研究发现,可通过严格地理论推导将传统意义上的调制波分解为2个子调制波,再进行SPWM调制,可以得到与SVPWM完全吻合的序列。该文在此方法基础上深入研究了8段以上(10、12、14段)的SVPWM调制序列与SPWM的统一。经过严格地理论推导,成功实现了含任意段数的SVPWM序列与SPWM的统一。仿真结果证明了该理论的正确性。CHEN Juan HE Yingjie WANG Xinyu LIU Jinjun 2013中国电机工程学报2013,33,9:28
9Senome-wide Association Studies in Maize: Praise and Stargaze显示文摘Yingjie Xiao Haijun Liu Liuji Wu Marilyn Warburton Jianbing Yan 2017Molecular Plant2017,10,3:27
10Antimony(V) removal from water by hydrated ferric oxides supported by calcite sand and polymeric anion exchanger显示文摘We fabricated and characterized two hybrid adsorbents originated from hydrated ferric oxides(HFOs) using a polymeric anion exchanger D201 and calcite as host. The resultant adsorbents(denoted as HFO-201 and IOCCS) were employed for Sb(V) removal from water. Increasing solution pH from 3 to 9 apparently weakened Sb(V) removal by both composites, while increasing temperature from 293 to 313 K only improved Sb(V) uptake by IOCCS. HFO-201 exhibited much higher capacity for Sb(V) than for IOCCS in the absence of other anions in solution. Increasing ionic strength from 0.01 to 0.1 mol/L NaNO3would result in a significant drop of the capacity of HFO-201 in the studied pH ranges; however, negligible effect was observed for IOCCS under similar conditions. Similarly, the competing chloride and sulfate pose more negative effect on Sb(V) adsorption by HFO-201 than by IOCCS, and the presence of silicate greatly decreased their adsorption simultaneously, while calcium ions were found to promote the adsorption of both adsorbents. XPS analysis further demonstrated that preferable Sb(V) adsorption by both hybrids was attributed to the inner sphere complexation of Sb(V) and HFO, and Ca(II) induced adsorption enhancement possibly resulted from the formation of HFO-Ca-Sb complexes. Column adsorption runs proved that Sb(V) in the synthetic water could be effectively removed from 30 μg/L to below 5 μg/L(the drinking water standard regulated by China), and the effective treatable volume of IOCCS was around 6 times as that of HFO-201, implying that HFO coatings onto calcite might be a more effective approach than immobilization inside D201.Yangyang Miao Feichao Han Bingcai Pan Yingjie Niu Guangze Nie Lu Lv 2014Journal of Environmental Sciences2014,26,2:20
11Fegeneration of functional alveoli by adult human SOX9^+ airway basal cell transplantation显示文摘Qiwang Ma Yu Ma Xiaotian Dai Tao Ren Yingjie Fu Wenbin Liu Yufei Han Yingchuan Wu Yu Cheng Ting Zhang Wei Zuo 2018Protein & Cell2018,9,3:20
12Ternary NiCoP nanosheet arrays: An excellent bifunctional catalyst for alkaline overall water splitting显示文摘为氢和氧进化反应探索 bifunctional 催化剂(她和 OER ) 与高度,效率,低费用,和容易的集成为未来是极其关键的可更新的精力系统。此处,第三的 NiCoP nanosheet 数组(NSA ) 被 phosphorization 跟随的一个灵巧的热水的方法在 3D Ni 泡沫上制作。这些数组作为 bifunctional 服务碱的催化剂,展出为 HER 和 OER 的优秀 electrocatalytic 性能和好工作稳定性。分别地,要求为 HER 和 OER 驾驶 50 妈 / 厘米 2 的当前的密度的 NiCoP NSA 电极的过电位象 133 和 308 mV 一样低它被归功于到优秀内在的 electrocatalytic 活动,快电子运输,和唯一的 superaerophobic 结构。当 NiCoP 综合作为时阳极并且 cathodic 材料, electrolyzer 要求了象~一样低的一个潜力为切开的全面的水驾驶 50 妈/厘米2的当前的密度的 1.77 V ,它是比用基于磷化物的材料的一样的类型的报导 electrolyzer 小得多的并且比 Pt/C 和 Ir/C 的联合甚至好,最好已知的高贵基于金属的电极。联合令人满意的工作稳定性和高活动,这个 NiCoP 电极为探索切开催化剂的全面的水铺平道路。Yingjie Li Haichuan Zhang Ming Jiang Yun Kuang Xiaoming Sun Xue Duan 2016Nano Research2016,9,8:20
13Mapping the hotspots and coldspots of ecosystem services in conservation priority setting显示文摘空间明确地热点和 coldspots 印射是在将保存放为生态系统服务(ES ) 的优先级的一个重要连接。然而,很少研究都没识别并且测试了他们的 ES 热点和 coldspots 的紧密和效率,它可以削弱生态的保存的有效性。在这学习,基于 RUSLE 模型和 Getis-Ord 官方补给 * 统计,我们确定了年度土壤保存服务(SC ) 的变化并且从 2000 ~ 2013 在中国的 Shaanxi 省识别了统计上重要的热点和 coldspots。结果显示那, 1 ) 有高 SC 的区域也介绍了一个显著地增加的趋势,当有低 SC 的区域仅仅稍微变化了时;2 ) SC 热点和 coldspots 证明热点主要是的明显的空间 differentiationthe 空间地在南部的 Shaanxi 聚集了,当 coldspots 主要在 Guanzhong 盆和沙多风的高原被散布时;并且 3 ) 识别热点有提供 SC 的最高的能力,与提供的 29.6% 全部的区域, 59.7% 总数满足。相反, coldspots 占据了 46.3% 全部的区域,但是仅仅提供了 17.2% 全部的 SC。除了保存单个 ES, Getis-Ord 官方补给 * 统计方法能也帮助为保存多重 ES 和生物多样性识别多功能的优先级区域。LI Yingjie ZHANG Liwei YAN Junping WANG Pengtao HU Ningke CHENG Wei FU Bojie 2017Journal of Geographical Sciences2017,27,6:19
14Deep-learning-based information mining from ocean remote-sensing imagery显示文摘With the continuous development of space and sensor technologies during the last 40 years,ocean remote sensing has entered into the big-data era with typical five-V(volume,variety,value,velocity and veracity)characteristics.Ocean remote-sensing data archives reach several tens of petabytes and massive satellite data are acquired worldwide daily.To precisely,efficiently and intelligently mine the useful information submerged in such ocean remote-sensing data sets is a big challenge.Deep learning-a powerful technology recently emerging in the machine-learning field-has demonstrated its more significant superiority over traditional physical-or statistical-based algorithms for image-information extraction in many industrial-field applications and starts to draw interest in ocean remote-sensing applications.In this review paper,we first systematically reviewed two deep-learning frameworks that carry out ocean remote-sensing-image classifications and then presented eight typical applications in ocean internal-wave/eddy/oil-spill/coastal-inundation/sea-ice/green-algae/ship/coral-reef mapping from different types of ocean remote-sensing imagery to show how effective these deep-learning frameworks are.Researchers can also readily modify these existing frameworks for information mining of other kinds of remote-sensing imagery.Xiaofeng Li Bin Liu Gang Zheng Yibin Ren Shuangshang Zhang Yingjie Liu Le Gao Yuhai Liu Bin Zhang Fan Wang 2020National Science Review2020,7,10:19
15Visualization Experiments of a Specific Fuel Flow Through Quartz-glass Tubes Under both Sub- and Supercritical Conditions显示文摘The present work is a visualization study of a typical kerosene (RP-3) flowing through vertical and horizontal quartz-glass tubes under both suband supercritical conditions by a high speed camera. The experiments are accomplished at temperatures of 300-730 K under pressures from 0.107-5 MPa. Six distinctive two-phase flow patterns are observed in upward flow and the critical point of RP-3 is identified as critical pressure pc=2.33 MPa and critical temperature Tc=645.04 K and it is found that when the fluid pressure exceeds 2.33 MPa the flow can be considered as a single phase flow. The critical opalescence phenomenon of RP-3 is observed when the temperature is between 643.16 K and 648.61 K and the pressure is between 2.308 MPa and 2.366 MPa. The region filled by the critical opalescence in the upward flow is clearly larger than that in the downward flow due to the interaction between the buoyancy force and fluid inertia. Morecover, obvious layered flow phenomenon is observed in horizontal flow under supercritical pressures due to the differences of gravity and density.DENG Hongwu ZHANG Chunben XU Guoqiang TAO Zhi ZHU Kun WANG Yingjie 2012Chinese Journal of Aeronautics2012,25,3:18
16Building damage in Dujiangyan during Wenchuan Earthquake显示文摘A field damage survey of 1,005 buildings damaged by the Wenchuan Earthquake in Dujiangyan City was carried out and the resulting data was analyzed using the statistical method. It is shown that buildings that were seismically designed achieved the desired seismic fortification target; they sustained less damage than the non-seismically designed buildings. Among the seismically designed buildings investigated, RC frame buildings performed the best in terms of seismic resistance. Masonry buildings with a ground story of RC frame structure were the second best, and masonry buildings performed the worst. Considering building height, multistory buildings sustained more severe damage than high-rise buildings and 2- and 3-story buildings. Compared to residential buildings, public buildings, such as schools and hospitals, suffered more severe damage.Zhang Minzheng and Jin Yingjie Institute of Engineering Mechanics, China Earthquake Administration, Harbin 150080, China Professor Graduate Student 2008Earthquake Engineering and Engineering Vibration2008,7,3:13
17Distant eQTLs and Non-coding Sequences Play Critical Roles in Regulating Gene Expression and Quantitative Trait Variation in Maize显示文摘Haijun Liu Xin Luo Luyao Niu Yingjie Xiao Lu Chen Jie Liu Xiaqing Wang Minliang Jin Wenqiang Li Qinghua Zhang Jianbing Yan 2017Molecular Plant2017,10,3:13
18The new interpretation of support vector machines on statistical learning theory显示文摘This paper is concerned with the theoretical foundation of support vector machines (SVMs). The purpose is to develop further an exact relationship between SVMs and the statistical learning theory (SLT). As a representative, the standard C-support vector classification (C-SVC) is considered here. More precisely, we show that the decision function obtained by C-SVC is just one of the decision functions obtained by solving the optimization problem derived directly from the structural risk minimization principle. In addition, an interesting meaning of the parameter C in C-SVC is given by showing that C corresponds to the size of the decision function candidate set in the structural risk minimization principle.ZHANG ChunHua 1 , TIAN YingJie 2 & DENG NaiYang 3,1 School of Information, Renmin University of China, Beijing 100872, China 2 Research Center on Fictitious Economy and Data Science, Chinese Academy of Sciences, Beijing 100080, China 3 College of Science, China Agricultural University, Beijing 100083, China 2010Science China Mathematics2010,53,1:12
19Discovery of the Plagiogranites in the Diyanmiao Ophiolite,Southeastern Central Asian Orogenic Belt,Inner Mongolia,China and Its Tectonic Significance显示文摘In this study, plagiogranites in the Diyanmiao ophiolite of the southeastern Central Asian Orogenic Belt(Altaids) were investigated for the first time. The plagiogranites are composed predominantly of albite and quartz, and occur as irregular intrusive veins in pillow basalts. The plagiogranites have high SiO_2(74.37–76.68 wt%) and low Al_2O_3(11.99–13.30 wt%), and intensively high Na_2O(4.52–5.49 wt%) and low K_2O(0.03–0.40 wt%) resulting in high Na_2O/K_2O ratios(11.3–183). These rocks are classified as part of the low-K tholeiitic series. The plagiogranites have low total rare earth element contents(∑REE)(23.62–39.77 ppm), small negative Eu anomalies(δEu=0.44–0.62), and flat to slightly LREE-depleted chondrite-normalized REE patterns((La/Yb)N=0.68–0.76), similar to N-MORB. The plagiogranites are also characterized by Th, U, Zr, and Hf enrichment, and Nb, P, and Ti depletion, have overall flat primitivemantle-normalized trace element patterns. Field and petrological observations and geochemical data suggest that the plagiogranites in the Diyanmiao ophiolite are similar to fractionation-type plagiogranites. Furthermore, the REE patterns of the plagiogranites are similar to those of the gabbros and pillow basalts in the ophiolite. In plots of SREE–SiO_2, La–SiO_2, and Yb–SiO_2, the plagiogranites, pillow basalts, and gabbros show trends typical of crystal fractionation. As such, the plagiogranites are oceanic in origin, formed by crystal fractionation from basaltic magmas derived from depleted mantle, and are part of the Diyanmiao ophiolite. LA–ICP–MS U–Pb dating of zircons from the plagiogranites yielded ages of 328.6±2.1 and 327.1±2.1 Ma, indicating an early Carboniferous age for the Diyanmiao ophiolite. These results provide petrological and geochronological evidence for the identification of the Erenhot–Hegenshan oceanic basin and Hegenshan suture of the Paleo-Asian Ocean.LI Yingjie WANG Jinfang WANG Genhou DONG Peipei LI Hongyang HU Xiaojia 2018Acta Geologica Sinica(English Edition)2018,92,2:12
20Two-dimensional nanomaterials: fascinating materials in biomedical field显示文摘Due to their high anisotropy and chemical functions,two-dimensional(2D)nanomaterials have attracted increasing interest and attention from various scientific fields,including functional electronics,catalysis,supercapacitors,batteries and energy materials.In the biomedical field,2D nanomaterials have made significant contributions to the field of nanomedicine,especially in drug/gene delivery systems,multimodal imaging,biosensing,antimicrobial agents and tissue engineering.2D nanomaterials such as graphene/graphene oxide(GO)/reduced graphene oxide(r GO),silicate clays,layered double hydroxides(LDHs),transition metal dichalcogenides(TMDs),transition metal oxides(TMOs),black phosphorus(BP),graphitic carbon nitride(g-C3N4),hexagonal boron nitride(h-BN),antimonene(AM),boron nanosheets(B NSs)and tin telluride nanosheets(Sn Te NSs)possess excellent physical,chemical,optical and biological properties due to their uniform shapes,high surface-to-volume ratios and surface charge.In this review,we first introduce the properties,structures and synthetic strategies of different configurations of 2D nanomaterials.Recent advances and paradigms of 2D nanomaterials in a variety of biomedical applications,ranging from drug delivery,cancer treatment,bioimaging and tissue engineering to biosensing are discussed afterwards.In the final part,we foresee the development prospects and challenges of 2D nanomaterials after summarizing the research status of ultrathin 2D nanomaterials.Tingting Hu Xuan Mei Yingjie Wang Xisheng Weng Ruizheng Liang Min Wei 2019Science Bulletin2019,64,22:12
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