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| 1 | Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing,China显示文摘Previous studies have showed clinical characteristics of patients with the 2019 novel coronavirus disease(COVID-19)and the evidence of person-to-person transmission.Limited data are available for asymptomatic infections.This study aims to present the clinical characteristics of 24 cases with asymptomatic infection screened from close contacts and to show the transmission potential of asymptomatic COVID-19 virus carriers.Epidemiological investigations were conducted among all close contacts of COVID-19 patients(or suspected patients)in Nanjing,Jiangsu Province,China,from Jan 28 to Feb 9,2020,both in clinic and in community.Asymptomatic carriers were laboratory-confirmed positive for the COVID-19 virus by testing the nucleic acid of the pharyngeal swab samples.Their clinical records,laboratory assessments,and chest CT scans were reviewed.As a result,none of the 24 asymptomatic cases presented any obvious symptoms while nucleic acid screening.Five cases(20.8%)developed symptoms(fever,cough,fatigue,etc.)during hospitalization.Twelve(50.0%)cases showed typical CT images of ground-glass chest and 5(20.8%)presented stripe shadowing in the lungs.The remaining 7(29.2%)cases showed normal CT image and had no symptoms during hospitalization.These 7 cases were younger(median age:14.0 years;P=0.012)than the rest.None of the 24 cases developed severe COVID-19 pneumonia or died.The median communicable period,defined as the interval from the first day of positive nucleic acid tests to the first day of continuous negative tests,was 9.5 days(up to 21 days among the 24 asymptomatic cases).Through epidemiological investigation,we observed a typical asymptomatic transmission to the cohabiting family members,which even caused severe COVID-19 pneumonia.Overall,the asymptomatic carriers identified from close contacts were prone to be mildly ill during hospitalization.However,the communicable period could be up to three weeks and the communicated patients could develop severe illness.These results highlighted the importance of close contact tracing and longitudinally surveillance via virus nucleic acid tests.Further isolation recommendation and continuous nucleic acid tests may also be recommended to the patients discharged. | Zhiliang Hu Ci Song Chuanjun Xu Guangfu Jin Yaling Chen Xin Xu Hongxia Ma Wei Chen Yuan Lin Yishan Zheng Jianming Wang Zhibin Hu Yongxiang Yi Hongbing Shen | 2020 | Science China(Life Sciences)2020，63，5： | 77 |
| 2 | 风电场电缆集电网操作过电压的模拟试验和暂态分析显示文摘为了解决大型风力发电场中压电缆集电网系统的暂态过电压防护及绝缘配合问题以提高风电场运行的安全可靠性,搭建了风力发电场中压电缆集电网系统的实验室模拟试验平台,并建立了相应的电磁暂态分析模型,研究了真空断路器的操作在风电场中压电缆集电网系统中产生的暂态过电压的特性。采用永磁操作真空断路器的选相位技术来测量最大操作过电压水平,得到了操作过电压水平与电缆长度、感性负载和断路器动作相角的密切关系。模拟试验结果表明,短电缆和大感性负载时开断断路器会产生最高的过电压,真空断路器发生重燃现象时过电压标幺值可达5。模拟200 MW风电场的暂态仿真分析表明,重合闸操作可产生最高2.4的过电压标幺值。 | 刘学忠 王贤宗 Li Yishan Abdul Saboor 尚雨辰 张天龙 | 2014 | 高电压技术2014，40，1： | 26 |
| 3 | Development and validation of an endoscopic images-based deep learning model for detection with nasopharyngeal malignancies显示文摘Background:Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperpla-sia,the positive rate for malignancy identification during biopsy is low,thus leading to delayed or missed diagnosis for nasopharyngeal malignancies upon initial attempt.Here,we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies under endoscopic examination based on deep learning.Methods:An endoscopic images-based nasopharyngeal malignancy detection model(eNPM-DM)consisting of a fully convolutional network based on the inception architecture was developed and fine-tuned using separate training and validation sets for both classification and segmentation.Briefly,a total of 28,966 qualified images were collected.Among these images,27,536 biopsy-proven images from 7951 individuals obtained from January 1st,2008,to December 31st,2016,were split into the training,validation and test sets at a ratio of 7:1:2 using simple randomiza-tion.Additionally,1430 images obtained from January 1st,2017,to March 31st,2017,were used as a prospective test set to compare the performance of the established model against oncologist evaluation.The dice similarity coef-ficient(DSC)was used to evaluate the efficiency of eNPM-DM in automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images,by comparing automatic segmentation with manual segmenta-tion performed by the experts.Results:All images were histopathologically confirmed,and included 5713(19.7%)normal control,19,107(66.0%)nasopharyngeal carcinoma(NPC),335(1.2%)NPC and 3811(13.2%)benign diseases.The eNPM-DM attained an overall accuracy of 88.7%(95%confidence interval(CI)87.8%-89.5%)in detecting malignancies in the test set.In the prospective comparison phase,eNPM-DM outperformed the experts:the overall accuracy was 88.0%(95%CI 86.1%-89.6%)vs.80.5%(95%CI 77.0%-84.0%).The eNPM-DM required less time(40 s vs.110.0±5.8 min)and exhibited encouraging performance in automatic segmentation of nasopharyngeal malignant area from the background,with an average DSC of 0.78±0.24 and 0.75±0.26 in the test and prospective test sets,respectively.Conclusions:The eNPM-DM outperformed oncologist evaluation in diagnostic classification of nasopharyngeal mass into benign versus malignant,and realized automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images. | Chaofeng Li Bingzhong Jing Liangru Ke Bin Li Weixiong Xia Caisheng He Chaonan Qian Chong Zhao Haiqiang Mai Mingyuan Chen Kajia Cao Haoyuan Mo Ling Guo Qiuyan Chen Linquan Tang Wenze Qiu Yahui Yu Hu Liang Xinjun Huang Guoying Liu Wangzhong Li Lin Wang Rui Sun Xiong Zou Shanshan Guo Peiyu Huang Donghua Luo Fang Qiu Yishan Wu Yijun Hua Kuiyuan Liu Shuhui Lv Jingjing Miao Yanqun Xiang Ying Sun Xiang Guo Xing Lv | 2018 | Cancer Communications2018，38，1： | 9 |
| 4 | Epidemiological Characteristics of Human Brucellosis-China,2016−2019显示文摘Introduction:Brucellosis is an important zoonotic infectious disease with its main mode of transmission from livestock to humans.The study analyzed epidemiological characteristics of human brucellosis from 2016 to 2019 in China,aiming to understand progress of the National Program of Brucellosis Prevention and Control.Methods:The research obtained data on human brucellosis cases reported through China’s National Notifiable Disease Reporting System(NNDRS)from January 1,2016 to December 31,2019 and described brucellosis epidemiological patterns by region,seasonality,age,sex,and occupation.Results:The number of cases reported nationwide in China decreased from 47,139(3.4/100,000)in 2016 to 37,947(2.7/100,000)in 2018,and then increased to 44,036(3.2/100,000)in 2019,with an average annual incidence of 3.0/100,000 during the four study years.Brucellosis in Xinjiang declined from 35.6/100,000 in 2016 to 16.3/100,000 in 2019-an average annual decrease of 22.9%.Brucellosis in Inner Mongolia increased from 23.8/100,000 in 2016 to 54.4/100,000 in 2019-an average increase of 31.8%per year and accounting for 22%of all reported cases.Northern China reported 95.2%of cases during this period and still had an incidence of 7.2/100,000 and 87.0%of counties being affected by brucellosis in 2019.In this region in 2019,males aged 45-64 years old had an incidence of over 15.9/100,000,compared with over 7.0/100,000 among females aged 45-64 years old.Conclusions:Although there was progress in prevention and control of human brucellosis in some provincial-level administrative divisions(PLADs)in 2016 through 2019,progress was limited nationwide and there was an overall resurgence of brucellosis in 2019.The resurgence was primarily in Inner Mongolia.An One Health approach should be strengthened to ensure successful and sustainable brucellosis prevention and control in China. | Zhongfa Tao Qiulan Chen Yishan Chen Yu Li Di Mu Huimin Yang Wenwu Yin | 2021 | China CDC weekly2021，3，6： | 6 |
| 5 | Performance analysis of FFH / BPSK system with partial band noise jamming and channel estimation error in high-mobility wireless communication scenarios显示文摘In this paper,we analyze the bit error ratio(BER) of fast frequency hopping(FFH) system with binary phase shift keying(BPSK) in high-mobility wireless channels.By taking into account partial band noise jamming and channel estimation errors as Gaussian noise,both of maximal-ratio combining(MRC) and equal-gain combining(EGC) schemes are considered,and exact analytical BER expressions for MRC and EGC schemes are obtained.Especially,a closed-form BER expression for the MRC scheme is also presented in high signal-to-noise ratio region.Analytical and simulation results demonstrate that,the FFH/BPSK schemes suffer from performance degradation in the presence of channel estimation errors.The worst case jamming factor is shown to be inversely proportional to the signal to jamming ratio.With properly designed frequency hopping schemes and channel estimation schemes,the performance improvement is also observed as compared with the traditional noncoherent FFH/BFSK system. | Yishan He Yufan Cheng Gang Wu Shaoqian Li | 2014 | Chinese Science Bulletin2014，59，35： | 6 |
| 6 | Ultrashort Bessel beam photoinscription of Bragg grating waveguides and their application as temperature sensors显示文摘Ultrashort pulsed Bessel beams with intrinsic nondiffractive character and potential strong excitation confinement down to 100nm can show a series of advantages over Gaussian beams in fabricating efficient Bragg grating waveguides(BGWs).In this work, we focus on parameter management for the inscription of efficient BGWs using the point-by-point method employing Bessel beams.Due to their high aspect ratio, the resulting one-dimensional void-like structures can section the waveguides and interact efficiently with the optical modes. Effective first-order BGWs with low birefringence can then be fabricated in bulk fused silica. By controlling the size and the relative location of grating voids via the Bessel pulse energy and scan velocities, the resonant behaviors of BGWs can be well regulated.A high value of 34 dB for 8 mm length is achieved.A simple predictive model for BGWs is proposed for analyzing the influences of processing parameters on the performance of BGWs. The technique permits multiplexing several gratings in the same waveguide.Up to eight grating traces were straightforwarcliy inscribed into the waveguide in a parallel-serial combined mode, forming the multiplex BGWs.As an application, the multiplex BGW sensor with two resonant peaks is proposed and fabricated for improving the reliability of temperature detection. | Guodong Zhang Guanghua Cheng Manoj K.Bhuyan Ciro D'Amico Yishan Wang Razvan Stoian | 2019 | Photonics Research2019，7，7： | 6 |
| 7 | Extradural injections and manual repositioning of spine in treatment of megalgia caused by cervical spondylotic radiculopathy显示文摘OBJECTIVE: To ascertain if it is effective to use extradural injections and manual repositioning of the spine to treat megalgia caused by cervical spondylotic radiculopathy (CSR). METHODS: Patients with megalgia caused by CSR were divided into a treatment group (n=46) treated by extradural injection and manual repositioning of the spine and a control group (n=46) treated by a conventional method. RESULTS: The prevalence of cure was 58.69% and the total prevalence of effective cure in the treatment group was 97.83% and was 23.91% and 78.26%, respectively, in the control group: this difference between the two groups was significant (P< 0.05). CONCLUSION: Treatment of megalgia caused by CSR by extradural injections and manual repositioning of the spine has a good curative effect with rapid analgesia and short therapeutic course. | Yishan Liu Xia Liu Xiangyang Zhang Hong Zhang | 2013 | Journal of Traditional Chinese Medicine2013，33，1： | 5 |
| 8 | Skin collagen fiber-based radar absorbing materials显示文摘By using skin collagen fiber (CF) as raw material,Schiff base structure containing CF (Sa-CF) was synthesized through CF-salicylaldehyde reaction.Then a novel radar absorbing material (Fe-Sa-CF) was prepared by chelating reaction between Sa-CF and Fe 3+.The coaxial transmission and reflection method was used to analyze the complex permittivity and complex magnetic permeability of these CF-based materials,and the radar cross section (RCS) method was used to investigate their radar absorbing properties in the frequency range of 1.0-18.0 GHz.Experimental results indicated that the conductivity of CF increased from initial 1.08×10-11 to 2.86×10-6 S/cm after being transferred into Fe-Sa-CF,and its dielectric loss tangent (tanδ) in the frequency range of 1.0-17.0 GHz also increased.These facts suggest that the Fe-Sa-CF is electric-loss type radar absorbing material.In the frequency range of 3.0-18.0 GHz,Sa-CF (1.0 mm in thickness) exhibited somewhat radar absorbing property with maximum radar reflection loss (RL) of-4.73 dB.As for Fe-Sa-CF,the absorbing bandwidth was broadened,and the absorbing intensity significantly increased in the frequency range of 1.0-18.0 GHz where a maximum radar RL of-9.23 dB was observed.In addition,the radar absorbing intensity of Fe-Sa-CF can be further improved by increasing membrane thickness.When the thickness reached to 2.0 mm,the RL values of Fe-Sa-CF were-15.0-18.0 dB in the frequency range of 7.0-18.0 GHz.Consequently,a kind of novel radar absorbing material can be prepared by chemical modification of collagen fiber,which is characterized by thin thickness,low density,broad absorption bandwidth and high absorption intensity. | LIU YiShan HUANG Xin GUO PeiPei LIAO XuePin SHI Bi | 2011 | Chinese Science Bulletin2011，56，2： | 5 |
| 9 | Robust sensor faults detection for induction motor using observer显示文摘当前的传感器是在正式就职马达的控制系统的关键元素之一。反映马达操作地位的变量的精确测量是否能被做,将直接在马达系统上并且因此影响控制效果传感器差错的及时、精确察觉是必要的。这份报纸向前根据正式就职马达的数学模型带剩余产生和差错察觉的一个 observerbased 方法。当非线性的部分是否满足 Lipschitz 条件,不限制观察员设计,如此的一个观察员的申请被扩展。同时,在柔韧的错误之间的矛盾和差错敏感也被解决。如此的方法的正确性和有效性被在也阐明工程实践的模仿的差错上的试验性的测试验证。 | Changfan ZHANG Yishan HUANG Rui SHAO | 2012 | 控制理论与应用(英文版)2012，10，4： | 4 |
| 10 | In vitro Inhibitory Activity of Shisandra chinensis and Polygonatum sibiricum against Vibrio harveyi and Its Biofilms显示文摘[Objective] This study aimed to analyze the in vitro inhibitory activity of Shisandra chinensis and Polygonatum sibiricum against Vibrio harveyi and its biofilms. [Result] By agar diffusion test,in vitro inhibitory activity of S.chinensis and P. sibiricum against V. harveyi was investigated. The minimal inhibitory concentration(MIC) a nd minimal bactericidal concentration(MBC) of S.chinensis and P.sibiricum against V.harveyi were determined by doubling dilution method. The inhibitory activity of S. chinensis and P.sibiricum on the formation of V.harveyi biofilms was evaluated by modified MTT assay. [Result]Both S.chinensis and P.sibiricum had inhibitory activity against V.harveyi. The inhibition zone diameter of S.chinensis against V.harveyi was 17.95 mm; MIC and MBC of S.chinensis were both 3.125 mg / ml. The inhibition zone diameter of P. sibiricum against V.harveyi was 12.22 mm; MIC and MBC of P.sibiricum were 3.125 and 6. 250 mg / ml,respectively. When the concentration was higher than 6. 25 mg / ml,S.chinensis decoction had extremely significant inhibitory activity against V.harveyi( P < 0. 01); when the concentration was higher than 3. 125 mg / ml,P. sibiricum had extremely significant inhibitory activity against V. harveyi(P <0. 01). [Conclusion]S.chinensis and P.sibiricum could significantly inhibit V.harveyi and its biofilms. | Zhifeng HUANG Huanying PANG Yang HUANG Yucong HUANG Yishan LU Jichang JIAN | 2016 | Agricultural Biotechnology2016，5，4： | 4 |
| 11 | Damage characteristics and catastrophic failure mechanism of coal rock induced by gas adsorption under compression显示文摘To reveal the damage characteristics and catastrophic failure mechanism of coal rock caused by gas adsorption,physical tests and theoretical methods are employed.The results show that adsorption swelling can damage coal rock,which can be distinguished by fractal dimension.A fitting relationship between the adsorption damage and fractal dimension is proposed by experimental testing and theoretical analysis.High gas adsorption pressure proves to be the dominant factor that leads to coal failure softening and gas outburst disasters.Three main parameters concerning adsorption damage include the change rate of released energy density,the transition difference in the post-peak acoustic emission(AE)b value and the change rate of cumulative AE energy.Results show that all the three parameters present a step-type decreasing change with the increase in fractal dimension,and the fractal dimension shows a linear relationship within the same failure mode.Finally,a method is proposed to evaluate coal rock disaster transformation,based on the aforementioned three main parameters of adsorption damage. | Xiaochun Xiao Lei Wang Jun Xu Xiangfeng Lv Pengfei Guo Yishan Pan | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，3： | 3 |
| 12 | Non-dormant Axillary Bud 1 regulates axillary bud outgrowth in sorghum显示文摘Tillering contributes to grain yield and plant architecture and therefore is an agronomically important trait in sorghum(Sorghum bicolor).Here,we identified and functionally characterized a mutant of the Nondormant Axillary Bud 1(NAB1)gene from an ethyl methanesulfonate-mutagenized sorghum population.The nab1 mutants have increased tillering and reduced plant height.Map-based cloning revealed that NAB1encodes a carotenoid-cleavage dioxygenase 7(CCD7)orthologous to rice(Oryza sativa)HIGH-TILLERING DWARF1/DWARF17 and Arabidopsis thaliana MORE AXILLARY BRANCHING 3.NAB1 is primarily expressed in axillary nodes and tiller bases and NAB1 localizes to chloroplasts.The nab1 mutation causes outgrowth of basal axillary buds;removing these non-dormant basal axillary buds restored the wild-type phenotype.The tillering of nab1 plants was completely suppressed by exogenous application of the synthetic strigolactone analog GR24.Moreover,the nab1plants had no detectable strigolactones and displayed stronger polar auxin transport than wild-type plants.Finally,RNA-seq showed that the expression of genes involved in multiple processes,including auxin-related genes,was significantly altered in nab1.These results suggest that NAB1 functions in strigolactone biosynthesis and the regulation of shoot branching via an interaction with auxin transport. | Jun Chen Limin Zhang Mengjiao Zhu Lijie Han Ya Lv Yishan Liu Pan Li Haichun Jing Hongwei Cai | 2018 | Journal of Integrative Plant Biology2018，60，10： | 3 |
| 13 | Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster ( Pinctada fucata , Gould 1850) responding to bacterial challenge显示文摘 | Zhongliang Wang Zaohe Wu Jichang Jian Yishan Lu | 2008 | Fish and Shellfish Immunology2008，，4： | 2 |
| 14 | Effects of trips on the oscillatory flow of an axisymmetric hypersonic inlet with downstream throttle显示文摘Experimental investigations are conducted on an axisymmetric hypersonic inlet to evaluate the effects of trips on oscillatory flows. The model exit is throttled with a fixed block to generate oscillatory flows at a freestream Mach number of 6 in a conventional wind tunnel and a shock tunnel. Schlieren imaging and pressure measurements are adopted to record unsteady flow features.Results indicate that trips with a 1 mm thickness prominently suppress external separations, shorten oscillatory cycles, and modify pressure magnitudes. Trips can reduce the upstream movement ranges of separated shocks from nose regions to locations axially 142 mm downstream. The oscillatory cycles are shortened from 3.75 ms to 3.25 ms and from 4 ms to 3.13 ms in two facilities.Tripped cases generally exhibit higher pressure magnitudes than those of untripped cases, of which the increment is up to 21 times the freestream static pressure for the farthest downstream transducer in the shock tunnel. The effects of trips are related to the streamwise vortexes in wake flows, in which interactions between external separations modify the separated flow patterns and enhance the sustainment of the forebody boundary layers to backpressure. Flow processes causing increments of oscillatory frequencies and pressure magnitudes are analyzed, while the flow mechanisms dominating the processes still need to be clarified in the future. | Wenzhi GAO Zhufei LI Jiming YANG Yishan ZENG | 2018 | Chinese Journal of Aeronautics2018，31，2： | 2 |
| 15 | Anaerobic treatment of wastewater containing methanol in up-flow anaerobic sludge bed (UASB) reactor显示文摘The direct conversion of methanol into methane is the main process in anaerobic treatment of methanol containing wastewater.However,acetic acid can also be produced from methanol theoretically,which may probably result in an abrupt pH drop and deteriorate the anaerobic process.Therefore,it is interesting to know what would really happen in an anaerobic reactor treating methanol wastewater.In this study,an up-flow anaerobic sludge bed(UASB)reactor treating methanol wastewater was operated.The chemical oxygen demand(COD),acetic acid and pH of the effluent were monitored at different loadings and influent alkalinity.The results showed that the anaerobic reactor could be operated steadily at as low as 119 mg/L of influent alkalinity and high organic loading rate with no obvious pH drops.Volatile fatty acids accumulation was not observed even at strong shock loadings.The microorganisms in the sludge at the end of the test became homogeneous in morphology,which were mainly spherical or spheroidal in shape. | Yishan LIN Yanling HE Zhuo MENG Shucheng YANG | 2008 | Frontiers of Environmental Science & Engineering2008，2，2： | 2 |
| 16 | Numerical simulation and temporal characterization of dual-pumped microringresonator-based optical frequency combs显示文摘Dual-pumped microring-resonator-based optical frequency combs(OFCs) and their temporal characteristics are numerically investigated and experimentally explored. The calculation results obtained by solving the driven and damped nonlinear Schr?dinger equation indicate that an ultralow coupled pump power is required to excite the primary comb modes through a non-degenerate four-wave-mixing(FWM) process and, when the pump power is boosted, both the comb mode intensities and spectral bandwidths increase. At low pump powers, the field intensity profile exhibits a cosine variation manner with frequency equal to the separation of the two pumps, while a roll Turing pattern is formed resulting from the increased comb mode intensities and spectral bandwidths at high pump powers. Meanwhile, we found that the power difference between the two pump fields can be transferred to the newly generated comb modes, which are located on both sides of the pump modes, through a cascaded FWM process. Experimentally, the dual-pumped OFCs were realized by coupling two self-oscillating pump fields into a microring resonator. The numerically calculated comb spectrum is verified by generating an OFC with 2.0 THz mode spacing over 160 nm bandwidth. In addition, the formation of a roll Turing pattern at high pump powers is inferred from the measured autocorrelation trace of a 10 free spectral range(FSR) OFC. The experimental observations accord well with the numerical predictions. Due to their large and tunable mode spacing, robustness,and flexibility, the proposed dual-pumped OFCs could find potential applications in a wide range of fields,including arbitrary optical waveform generation, high-capacity optical communications, and signal-processing systems. | XIAOHONG HU WEIQIANG WANG LEIRAN WANG WENFU ZHANG YISHAN WANG WEI ZHAO | 2017 | Photonics Research2017，5，3： | 2 |
| 17 | Research on action of surfactants in process of coating copper on graphite powder显示文摘 | Yu Quanmao Wu Yishan | 1999 | Non-metallic Mines1999，22，3： | 1 |
| 18 | An Inves- tigation of Thermal Characteristics of a Liquid-cooled Mag- netorheological Fluid-based Clutch 显示文摘 | WANG Daoming ZI Bin ZENG Yishan | 2015 | Smart Materials and Structures2015，24，05： | 1 |
| 19 | Regularity in the Time-dependent Dis- tribution of the Percentage of Never-cited Papers: An Empirical Pilot Study Based on the Six Joumals显示文摘 | Zewen Hu Yishan Wu | 2014 | Journal of Infor-met- tics2014，8，2014： | 1 |
| 20 | Influence of Paeonia lactiflora roots extract on cAMP-phosphodiesterase activity and related anti-inflammatory action显示文摘 | Jiang DaiXun Chen YiShan Hou XiaoTao | 2011 | J Ethnopharmacol2011，1，137： | 1 |
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