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| 1 | Rural land use spatial allocation in the semiarid loess hilly area in China:Using a Particle Swarm Optimization model equipped with multi-objective optimization techniques显示文摘Semiarid loess hilly areas in China are enduring a series of environmental conflicts between urban expansion,cultivated land conservation,soil erosion and water shortage,and require land use allocation to reconcile these environmental conflicts.We argue that the optimized spatial allocation of rural land use can be achieved by a Particle Swarm Optimization (PSO) model in conjunction with multi-objective optimization techniques.Our study focuses on Yuzhong County of Gangsu Province in China,a typical catchment on the Loess Plateau,and proposes a land use spatial optimization model.The model maximizes land use suitability and spatial compactness based on a variety of constraints,e.g.optimal land use structure and restrictive areas,and employs an improved PSO algorithm equipped with a determinant initialization method and a dynamic weighted aggregation (DWA) method to obtain the optimized land use spatial pattern.The results suggest that (1) approximately 4% of land use should be reallocated and these changes would alleviate the environmental conflicts in the study area;(2) the major reshuffling is slope farmland and newly added construction and cultivated land,whereas the unchanged areas are largely forests and basic farmland;and (3) the PSO is capable of optimizing rural land use allocation,and the determinant initialization method and DWA can improve the performance of the PSO. | LIU YaoLin LIU DianFeng LIU YanFang HE JianHua JIAO LiMin CHEN YiYun HONG XiaoFeng | 2012 | Science China Earth Sciences2012，55，7： | 23 |
| 2 | Pathways of China's PM;air quality 2015–2060 in the context of carbon neutrality显示文摘Clean air policies in China have substantially reduced particulate matter(PM;) air pollution in recent years,primarily by curbing end-of-pipe emissions.However,reaching the level of the World Health Organization(WHO) guidelines may instead depend upon the air quality co-benefits of ambitious climate action.Here,we assess pathways of Chinese PM;air quality from 2015 to 2060 under a combination of scenarios that link global and Chinese climate mitigation pathways(i.e.global 2℃-and 1.5℃-pathways,National Determined Contributions(NDC) pledges and carbon neutrality goals) to local clean air policies.We find that China can achieve both its near-term climate goals(peak emissions) and PM;air quality annual standard(35 μg/m;) by 2030 by fulfilling its NDC pledges and continuing air pollution control policies.However,the benefits of end-of-pipe control reductions are mostly exhausted by 2030,and reducing PM;exposure of the majority of the Chinese population to below 10 μg/m;by 2060 will likely require more ambitious climate mitigation efforts such as China’ s carbon neutrality goals and global1.5℃-pathways.Our results thus highlight that China’s carbon neutrality goals will play a critical role in reducing air pollution exposure to the level of the WHO guidelines and protecting public health. | Jing Cheng Dan Tong Qiang Zhang Yang Liu Yu Lei Gang Yan Liu Yan Sha Yu Ryna Yiyun Cui Leon Clarke Guannan Geng Bo Zheng Xiaoye Zhang Steven JDavis Kebin He | 2021 | National Science Review2021，8，12： | 23 |
| 3 | Visible light-driven organic photochemical synthesis in China显示文摘In recent years, visible light-driven organic photochemical synthesis has attracted wide research interest from academic and industrial communities due to its features of green and sustainable chemistry. In this flourishing area, Chinese chemists have devoted great efforts to different aspects of synthetic chemistry. This review will summarize their representative work according to the following categories: C–H functionalization, synthesis of aromatic aza-heterocycles, asymmetric organic photochemical synthesis, transformations of small molecules and biomolecule-compatible reactions. | Yiyun Chen Liang-Qiu Lu Da-Gang Yu Cheng-Jian Zhu Wen-Jing Xiao | 2019 | Science China Chemistry2019，62，1： | 19 |
| 4 | Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass显示文摘The micro-alloying effects of Y on the microstructure, mechanical properties, and bio-corrosion behavior of Mg69-xZn27Ca4Yx(x= 0, 1, 2 at.%) alloys were investigated through X-ray diffraction, compressive tests,electrochemical treatments, and immersion tests. The Mg69Zn27Ca4 alloy was found to be absolutely amorphous, and its glass-forming ability decreased with the addition of Y. The Mg68Zn27Ca4Y1 alloy exhibited an ultrahigh compressive strength above 1010 MPa as well as high capacity for plastic strain above 3.1%.Electrochemical and immersion tests revealed that these Y-doped MgeZ neC a alloys had good bio-corrosion resistance in simulated body fluid(SBF) at 37℃. The results of the cytotoxicity test showed high cell viabilities for these alloys, which means good bio-compatibility. | Jingfeng Wang Yang Li Song Huang Yiyun Wei Xingfeng Xi Kaiyong Cai Fusheng Pan | 2014 | Journal of Materials Science & Technology2014，30，12： | 8 |
| 5 | Sonochemical effect of a bifrequency irradiation显示文摘The sonochemical effect of a bifrequency orthogonal ultrasonic irradiation has been studied by using two different detecting methods. It has been shown that the sonochemical yield produced by the bifrequency irradiation appears to be much more than the sum of the yields produced separately by the two irradiations. The bifrequency irradiation, therefore, can be expected to exert a great influence on the development of sonohemical | ZHU Changping, FENG Ruo & ZHAO Yiyun Department of Physics. Jingzhou Normal College, Jingzhou 434100, China State Key Laboratory of Modern Acoustics, Nanjing University, Nanjing 210093, China Chemistry Department of Yunnan University, Kunming 650091, Ch | 2000 | Chinese Science Bulletin2000，45，2： | 7 |
| 6 | All-small-molecule dynamic covalent gels with antibacterial activity by boronate-tannic acid gelation显示文摘Reversible boronate-catechol linkage was widely used to construct two-dimensional coatings and threedimensional nanostructures or hydrogels.The construction of these functional materials usually requires the pre-synthesis of macro molecular building blocks,and direct gelation between natural polyphenols and small molecule boranic acids is yet to be investigated.In this study,we fabricated a family of allsmall-molecule dynamic covalent gels consisting of tannic acid and boronic acids.Transparent and thixotropic gels were formed by boronate affinity towards catechol groups abundant on natural polyphenols.The gels showed multi-responsiveness,such as acid-,base-,reduction-and oxidantsensitive depending on the used boronic acid building blocks.The chemistry for gel formation and stimuli-responsiveness was characterized by11B NMR spectroscopy.The multi-stimuli responsiveness,green processing and facile modular design make the boronic acid-tannic acid gels promising candidates for the development of smart soft materials. | Xuejing Cheng Mengyu Li Hui Wang Yiyun Cheng | 2020 | Chinese Chemical Letters2020，31，3： | 6 |
| 7 | Thyroid hormone action in metabolic regulation显示文摘Thyroid hormone plays pivotal roles in growth,differentiation,development and metabolic homeostasis via thyroid hormone receptors(TRs)by controlling the expression of TR target genes.The transcriptional activity of TRs is modulated by multiple factors including various TR isoforms,diverse thyroid hormone response elements,different heterodimeric partners,coregulators,and the cellular location of TRs.In the present review,we summarize recent advance in understanding the molecular mechanisms of thyroid hormone action obtained from human subject research,thyroid hormone mimetics application,TR isoform-specific knock-in mouse models,and mitochondrion study with highlights in metabolic regulations.Finally,as future perspectives,we share our thoughts about current challenges and possible approaches to promote our knowledge of thyroid hormone action in metabolism. | Yiyun Song Xuan Yao Hao Ying | 2011 | Protein & Cell2011，2，5： | 3 |
| 8 | Common-Ion Effect Triggered Highly Sustained Seawater Electrolysis with Additional NaCl Production显示文摘Developing efficient seawater-electrolysis system for mass production of hydrogen is highly desirable due to the abundance of seawater.However,continuous electrolysis with seawater feeding boosts the concentration of sodium chloride in the electrolyzer,leading to severe electrode corrosion and chlorine evolution.Herein,the common-ion effect was utilized into the electrolyzer to depress the solubility of NaCl.Specifically,utilization of 6M NaOH halved the solubility of NaCl in the electrolyte,affording efficient,durable,and sustained seawater electrolysis in NaCl-saturated electrolytes with triple production of H_(2),O_(2),and crystalline NaCl.Ternary NiCoFe phosphide was employed as a bifunctional anode and cathode in simulative and Ca/Mg-free seawater-electrolysis systems,which could stably work under 500 mA/cm^(2) for over 100 h.We attribute the high stability to the increased Na^(+)concentration,which reduces the concentration of dissolved Cl-in the electrolyte according to the common-ion effect,resulting in crystallization of NaCl,eliminated anode corrosion,and chlorine oxidation during continuous supplementation of Ca/Mg-free seawater to the electrolysis system. | Pengsong Li Shiyuan Wang Imran Ahmed Samo Xingheng Zhang Zhaolei Wang Cheng Wang Yang Li Yiyun Du Yang Zhong Congtian Cheng Wenwen Xu Xijun Liu Yun Kuang Zhiyi Lu Xiaoming Sun | 2020 | Research2020，，1： | 3 |
| 9 | Joint Optimal Scheduling for Electric Vehicle Battery Swapping-charging Systems Based on Wind Farms显示文摘Insufficiencies in charging facilities limit the broad application of electric vehicles(EVs).In addition,EV can hardly represent a green option if its electricity primarily depends on fossil energy.Considering these two problems,this paper studies a battery swapping-charging system based on wind farms(hereinafter referred to as W-BSCS).In a W-BSCS,the wind farms not only supply electricity to the power grid but also cooperate with a centralized charge station(CCS),which can centrally charge EV batteries and then distribute them to multiple battery swapping stations(BSSs).The operational framework of the W-BSCS is analyzed,and some preprocessing technologies are developed to reduce complexity in modeling.Then,a joint optimal scheduling model involving a wind power generation plan,battery swapping demand,battery charging and discharging,and a vehicle routing problem(VRP)is established.Then a heuristic method based on the exhaustive search and the Genetic Algorithm is employed to solve the formulated NP-hard problem.Numerical results verify the effectiveness of the joint optimal scheduling model,and they also show that the W-BSCS has great potential to promote EVs and wind power. | Mingfei Ban Jilai Yu Yiyun Yao | 2021 | CSEE Journal of Power and Energy Systems2021，7，3： | 3 |
| 10 | Black carbon emissions in China显示文摘 | David G. Streets Shalini Gupta Stephanie T. Waldhoff Michael Q. Wang Tami C. Bond Bo Yiyun | 2001 | Atmospheric Environment2001，，25： | 2 |
| 11 | Satellite Image Adaptive Restoration Using Periodic Plus Smooth Image Decomposition and Complex Wavelet Packet Transforms显示文摘A satellite image adaptive restoration method was developed that avoids ringing artifacts at the image boundary and retains oriented features. The method combines periodic plus smooth image decomposition with complex wavelet packet transforms. The framework first decomposes a degraded satellite image into the sum of a 'periodic component' and a 'smooth component'. The Bayesian method is then used to estimate the modulation transfer function degradation parameters and the noise. The periodic component is deconvoluted using complex wavelet packet transforms with the deconvolution result of the periodic component then combined with the smooth component to get the final recovered result. Tests show that this strategy effectively avoids ringing artifacts while preserving local image details (especially directional textures) without amplifying the noise. Quantitative comparisons illustrate that the results are comparable with previous methods. Another benefit is that this approach can process large satellite images with parallel processing, which is important for practical use. | Yan Zhang Yiyun Man | 2012 | Tsinghua Science and Technology2012，17，3： | 2 |
| 12 | Determination of Copper, Nickel, Cobalt, Silver, Lead, Cadmium and Mercury Ions in Water by Solid Phase Extraction and the RP-HPLC with UV-Vis Detection显示文摘 | Hu Qiufen Yang Guangyu Zhao Yiyun | 2003 | Analytical and Bioanalytical Chemistry2003，375，6： | 2 |
| 13 | Design of Polymers for Intracellular Protein and Peptide Delivery显示文摘Cytosolic protein delivery techniques are of great importance for cell biology,biotechnology and protein drug development.The design of carriers with robust efficiency in cytosolic protein delivery is challenging.This account provides a progress report of polymeric carriers for this purpose in our group.During the past years,we have developed several types of functionalized polymers for cytosolic protein and peptide delivery by engineering polymers with ligands such as guanidinium,boronate,coordination ligands and fluoroalkyls.The designed polymers showed improved protein/peptide binding affinities,and successfully delivered various cargo proteins into the cytosol of living cells,while maintaining their bioactivity.In addition,the polymers showed potent efficiencies in the delivery of tumor antigens,therapeutic peptides,toxins and antioxidant proteins in vivo.We hope these polymers could be translated for protein delivery in the treatment of various diseases in the future. | Yiyun Cheng | 2021 | Chinese Journal of Chemistry2021，39，6： | 2 |
| 14 | PET/fMRI对异常脑活动的精准定位:研究进展与展望显示文摘许多脑疾病无明显病灶,其病因可能是源于脑活动或脑区连通性的异常。目前常用的脑成像诊断技术很难对其异常脑活动进行精准定位。新近发展起来的PET/MR一体同步显像技术或能弥补此缺陷。该设备已经用于临床诊断,但主要还是利用了PET功能影像与MRI结构影像的结合,远远没有发挥其"功能-功能"结合的诸多优势。目前,国际上PET/fMRI的研究尚处于起步阶段。初步研究表明,PET与fMRI常用功能指标之间的相关性并不高,提示2种功能指标可能揭示了不同的生理、病理机制。目前,我国大型研究型医院已经安装了至少5台一体化PET/MR设备。相对来说,我国的优势在于病源充足,PET影像发展迅速,且在fMRI的计算方法学方面有较高的国际地位。PET/fMRI的研究通常需要多学科的合作,包括核医学、放射学、化学、医用物理学、影像计算方法学、认知神经科学等等,我国医院的科研管理体制还需要改进,以满足这种多学科高度交叉合作的需求。利用自身优势,改进自身科研管理体制,再加上多中心合作,相信我国在PET/fMRI的研究方面能够很快达到国际一流水平,并取得既有科学价值、又有临床价值的科研成果。 | 臧玉峰 冯逢 霍力 李彪 兰晓莉 卢洁 田嘉禾 赵周社 Huang Yiyun | 2017 | 中华核医学与分子影像杂志2017，37，12： | 2 |
| 15 | Cyclic Iodine Reagents Enable Allylic Alcohols for Alkyl Boronate Addition/Rearrangement by Photoredox Catalysis显示文摘All-carbon quaternary centers are prevalent in bioactive small molecules.However,their efficient construction remains a formidable synthetic challenge.Here we report cyclic iodine(Ⅲ)reagents enable the synthesis of cyclopentanones,cyclohexanones,and dihydrofuranones bearing a-quaternary centers by photoredox catalysis.The reaction proceeds by the formation of the novel cyclic iodine(Ⅲ)reagent-allylic alcohol complex,which enables the first alkyl boronate addition and semi-pinacol rearrangement of allylic alcohols with dual alcohol and olefin activation.The reaction is suitable for gram scale synthesis and is transformable to alcohols,olefins,oximes,and lactones with an α-quaternary center in one step. | Mingshang Liu Hanchu Huang Yiyun Chen | 2018 | Chinese Journal of Chemistry2018，36，12： | 2 |
| 16 | Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2显示文摘SARS-CoV-2 has become a global pandemic threatening human health and safety.It is urgent to find effective therapeutic agents and targets with the continuous emergence of novel mutant strains.The knowledge of the molecular basis and pathogenesis of SARS-CoV-2 in host cells requires to be understood comprehensively.The unknown structure and function of nsp2 have hindered our understanding of its role in SARS-CoV-2 infection.Here,we report the crystal structure of the N-terminal of SARS-CoV-2 nsp2 to a high resolution of 1.96?.This novel structure contains three zinc fingers,belonging to the C2 H2,C4,and C2 HC types,respectively.Structure analysis suggests that nsp2 may be involved in binding nucleic acids and regulating intracellular signaling pathways.The binding to single or double-stranded nucleic acids was mainly through the large positively charged region on the surface of nsp2,and K111,K112,K113 were key residues.Our findings lay the foundation for a better understanding of the relationship between structure and function for nsp2.It is helpful to make full use of nsp2 as further research and development of antiviral targets and drug design. | Jun Ma Yiyun Chen Wei Wu Zhongzhou Chen | 2021 | Virologica Sinica2021，36，5： | 2 |
| 17 | Black carbon emissions in China显示文摘 | David G. Streets Shalini Gupta Stephanie T. Waldhoff Michael Q. Wang Tami C. Bond Bo Yiyun | 2001 | Atmospheric Environment2001，，25： | 2 |
| 18 | Outage Performance of Cognitive DF Relaying Networks Employing SWIPT显示文摘In this paper, the outage performance of a cognitive relaying network over Nakagami-m fading channels, employing simultaneous wireless information and power transfer(SWIPT) technology is analyzed and evaluated. The operation of this network is considered in conjunction with the conventional decode-and-forward(DF) and incremental DF(IDF) protocols. For the conventional DF protocol, it is assumed that there is no direct link between the secondary transmitter(S) and the secondary destination(D), while(for both protocols) after harvesting energy, the relay node(R) always helps to forward the resulting signal to D. However, for the IDF protocol, R assists in relaying S's information to D only when the direct communication between S and D has failed. Furthermore, for both DF and IDF protocols, we assume there is no power supply for R, and R harvests energy from the transmitted signal of S. We derive exact analytical expressions for the outage probability at D in DF and IDF protocols, respectively, in terms of the bivariate Meijer's G-function. Performance evaluation results obtained by means of Monte-Carlo simulations are also provided and have validated the correctness of the proposed analysis. | jing yang yiyun cheng kostas p.peppas p.takis mathiopoulos jie ding | 2018 | China Communications2018，15，4： | 2 |
| 19 | PDGFRαreporter activity identifies periosteal progenitor cells critical for bone formation and fracture repair显示文摘The outer coverings of the skeleton,which is also known as the periosteum,are arranged in concentric layers and act as a reservoir for tissue-specific bone progenitors.The cellular heterogeneity within this tissue depot is being increasingly recognized.Here,inducible PDGFRαreporter animals were found to mark a population of cells within the periosteum that act as a stem cell reservoir for periosteal appositional bone formation and fracture repair.During these processes,PDGFRαreporter^(+)progenitors give rise to Nestin+periosteal cells before becoming osteoblasts and osteocytes.The diphtheria toxin-mediated ablation of PDGFRαreporter^(+)cells led to deficits in cortical bone formation during homeostasis and a diminutive hard callus during fracture repair.After ossicle transplantation,both mouse PDGFRαreporter^(+)periosteal cells and human Pdgfrα+periosteal progenitors expand,ossify,and recruit marrow to a greater extent than their counterpart periosteal cells,whereas PDGFRαreporter^(−)periosteal cells exhibit a predisposition to chondrogenesis in vitro.Total RNA sequencing identified enrichment of the secreted factors Fermt3 and Ptpn6 within PDGFRαreporter^(+)periosteal cells,which partly underlie the osteoblastogenic features of this cell population. | Jiajia Xu Yiyun Wang Zhu Li Ye Tian Zhao Li Amy Lu Ching-Yun Hsu Stefano Negri Cammy Tang Robert J.Tower Carol Morris Aaron W.James | 2022 | Bone Research2022，10，1： | 2 |
| 20 | Evaluation of polyamidoamine (PAMAM) dendrimers as drug carriers of anti-bacterial drugs using sulfamethoxazole (SMZ) as a model drug显示文摘 | Minglu Ma Yiyun Cheng Zhenhua Xu Peng Xu Haiou Qu Yujie Fang Tongwen Xu Longping Wen | 2006 | European Journal of Medicinal Chemistry2006，，1： | 1 |
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