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| 1 | Target delineation and dose prescription of adaptive replanning intensity-modulated radiotherapy for nasopharyngeal carcinoma显示文摘Dear Editor,Intensity-modulated radiotherapy(IMRT)has a distinct advantage of high conformity and is an appropriate tech-nique for treating nasopharyngeal carcinoma(NPC).Pre-vious studies have demonstrated that anatomical changes in the external contour,shape,and location of the target and critical structures are significant and result in dosi-metric changes[1,2].Patients’quality of life and clini-cal outcomes might be improved by IMRT replanning[3].Therefore,replanning strategies should be consid-ered instead of single-planning strategies throughout the entire course of radiotherapy.However,there are sub-stantial controversies on(1)the appropriate time for tar-get redelineation,(2)how to modify the target volumes,and(3)how to evaluate the modified plans.The present study provides a new perspective in replanning with regard to these three aspects. | Dehuan Xie Wanqin Cheng Shaowen Lv Rui Zhong Lei Wang Jiang Hu Mingli Wang Shaomin Huang Yong Su Yunfei Xia | 2019 | Cancer Communications2019，39，1： | 7 |
| 2 | Genome-Wide Identification of Zn_(2)Cys_(6 ) Class Fungal-Specific Transcription Factors(ZnFTFs)and Functional Analysis of UvZnFTFI in Ustilaginoidea virens显示文摘Transcription factors(TFs)orchestrate the regulation of cellular gene expression and thereby determine cell functionality.In this study,we analyzed the distribution of TFs containing domains,which named as ZnFTFs,both in ascomycete and basidiomycete fungi.We found that ZnFTFs were widely distributed in these fungal species,but there was more expansion of the ZnFTF class in Ascomycota than Basidiomycota.We identified 40 ZnFTFs in Ustilaginoidea virens,and demonstrated the involvement of UvZnFTF1 in vegetative growth,conidiation,pigment biosynthesis and pathogenicity.RNA-Seq analysis suggested that UvZnFTF1 may regulate different nutrient metabolism pathways,the production of secondary metabolites,and the expression of pathogen-host interaction genes and secreted protein-encodi ng genes.Analysis of the distributi on of differe nt fungal TFs in U.virens further dem on strated that UvZnFTFs make up a large TF family and may play essential biological roles in U.virens. | SONG Tianqiao ZHANG Xiong ZHANG You LIANG Dong YAN Jiaoling YU Junjie YU Mina CAO Huijuan YONG Mingli PAN Xiayan QI Zhongqiang DU Yan ZHANG Rongsheng LIU Yongfeng | 2021 | Rice science2021，28，6： | 4 |
| 3 | A dynamic evalua tion model of university leading cadre based on multiva riate delay connection number显示文摘 | Tao Yong Shen Feifei Hu Mingli | 2012 | Kybernetes2012，41，5： | 1 |
| 4 | A dynamic evaluation model of university leading cadre based on multivariate delay connection number显示文摘 | Tao Yong Shen Feifei Hu Mingli | 2012 | Kybernetes2012，41，5： | 1 |
| 5 | Integrating preconcentration, tetrahydroborate immobilization, elution and chemical vapor genera tion onto a cellulose surface for the determination of cadmium with atomic fluorescence speetrometry显示文摘 | Chen Mingli Tian Yong Wang Jianhua | 2008 | Journal of Analytical Atomic SDectrometry2008，23，87： | 1 |
| 6 | A dynamic evaluation model of university leading cadre based on multivariate delay connection number显示文摘 | Tao Yong Shen Feifei Hu Mingli | 2012 | Kybernetes2012，41，5： | 1 |
| 7 | Controllable synthesis of carbon coils and growth mechanism for twinning double-helix catalyzed by Ni nanoparticle显示文摘 | Xian Jian Dingchuan Wang Hongyang Liu Man Jiang Zuowan Zhou Jun Lu Xiaoling Xu Yong Wang Li Wang Zizheng Gong Mingli Yang Jihua Gou David Hui | 2013 | Composites Part B2013，，： | 1 |
| 8 | UvSMEK1,a Suppressor of MEK Null,Regulates Pathogenicity,Conidiation and Conidial Germination in Rice False Smut Fungus Ustilaginoidea virens显示文摘Rice false smut,which is caused by Ustilaginoidea virens,is an emerging disease of rice spikelets in rice-growing areas worldwide.However,the infection mechanism of U.virens on rice spikelets is still unclear.Here,we characterized a suppressor of mitogen-activated protein kinase kinase or ERK kinase(MEK)null(UvSMEKI)in U.virens that is conserved among filamentous fungi.Compared with wild type U.virens strain P-1,UvSMEKI deletion mutants were defective in pathogenicity and conidial germination.In addition,conidiation of UvSMEKI deletion mutants was significantly reduced on yeast extract tryptone(YT)plates,but inc「eased in YT broth compared with the wild type.Compared with UvSMEKI expression level during the vegetative mycelia and conidiation stages,UvSMEKI dramatically increased during infection of rice florets.Surprisingly,the UvSMEKI deletion mutants exhibited higher tolerance to H_(2)O_(2) and NaCl.In summary,presented evidence suggested that UvSMEKI positively regulated pathogenicity,conidial germination and conidiation in YT broth,and negatively regulated conidiation on YT medium and tolerance to oxidative and osmotic stresses.The results enhanee our understanding of the regulatory mechanism of pathogenicity of U.virens,and present a potential molecular target for blocking rice infection by U.virens. | Yu Junjie Yu Mina SONG Tianqiao CAO Huijuan Yong Mingli Pan Xiayan Qi Zhongqiang Du Yan Zhang Rongsheng Yin Xiaole Liang Dong Liu Yongfeng | 2021 | Rice science2021，28，5： | 0 |
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