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| 1 | Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a global pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2).SARS-Co V-2 infection was first detected in Wuhan,China in late December 2019.The virus was spreading rapidly to other cities of China and accumulating cases had been reported(Li et al.2020). | Xiaoping Chen Qunqun Jiang Zhiyong Ma Jiaxin Ling Wenjia Hu Qian Cao Pingzheng Mo Lei Yao Rongrong Yang Shicheng Gao Xien Gui Wei Hou Yong Xiong Jinlin Li Yongxi Zhang | 2020 | Virologica Sinica2020，35，6： | 6 |
| 2 | Effects of magnesium on the performance of sows and their piglets显示文摘The objective of this study was to evaluate the effects of supplemental magnesium(Mg) on the performance of gilts and parity 3 sows and their piglets.Fifty-six gilts(Trial 1) and 56 sows(Trial 2) were assigned to one of 4treatments according to their mating weight,respectively.The treatments comprised corn-soybean meal based gestation and lactation diets(0.21%magnesium) supplemented with 0,0.015,0.03,or 0.045%Mg from mating until weaning.The results showed that magnesium supplementation significantly(P < 0.05) reduced the weaning to estrus interval in both gilts and sows.There were significant effects(P < 0.05) of supplemental magnesium on the total number of piglets born,born alive and weaned in sows.In late gestation and lactation,the digestibility of crude fiber(quadratic effects,P< 0.05),and crude protein(P< 0.05),were significantly influenced by magnesium in gilts and sows,respectively.There were differences among the 4 groups in terms of the apparent digestibility of dry matter and crude fiber in sows(P< 0.05) during both early and late gestation.The apparent digestibility of gross energy was increased for sows in late gestation(P< 0.05),and lactation(quadratic effects,P< 0.05).At farrowing and weaning,serum prolactin levels and alkaline phosphate activities linearly increased in sows as the Mg supplementation increased(P < 0.05).Serum Mg of sows at farrowing and serum urea nitrogen of sows at weaning was significantly influenced by Mg supplementation(P< 0.05).The Mg concentration in sow colostrum and the serum of their piglets were increased by supplemental magnesium(P < 0.05).In addition,growth hormone levels were linearly elevated(P< 0.05) in the serum of piglets suckling sows.Our data demonstrated that supplemental magnesium has the potential to improve the reproduction performance of sows,and the suitable supplemental dose ranged from 0.015%to 0.03%. | Jianjun Zang Jingshu Chen Ji Tian Aina Wang Hong Liu Shengdi Hu Xiangrong Che Yongxi Ma Junjun Wang Chunlin Wang Guanghua Du Xi Ma | 2015 | Journal of Animal Science and Biotechnology2015，6，1： | 3 |
| 3 | A uniplanar compact photonic-bandgap (UC-PBG) structure and its applications for microwave circuit 显示文摘 | Yang Feiran Ma Kuangping Qian Yongxi | 1999 | IEEE Trans MTT1999，47，8： | 1 |
| 4 | A uniplanar compact photonie-bandgap (UC-PBG) stl:ucture and its application for microwave circuits显示文摘 | Yang Feiran Ma Kuangping Qian Yongxi | 1999 | IEEE Transactions on Microwave Theory and Techniques1999，47，8： | 1 |
| 5 | A Novel Waveguide Using Uniplanar Compact Photonic-Bandgap (UC-PBG) Structure显示文摘 | Yang F R Kuang-Ping Ma Yongxi Qian | 1999 | IEEE Trans on MTT1999，47，11： | 1 |
| 6 | Supplementation with alpha-glycerol monolaurate during late gestation and lactation enhances sow performance,ameliorates milk composition,and improves growth of suckling piglets显示文摘Background Physiological changes during lactation cause oxidative stress in sows,reduce immunity,and hamper the growth capacity of piglets.Alpha-glycerol monolaurate(α-GML)has potential for enhancing the antimicrobial activity of sows and the growth of suckling piglets.Methods Eighty sows were allocated randomly to four groups:basal diet and basal diets supplemented with 500,1000,or 2000 mg/kgα-GML.The experiment started on d 85 of gestation and lasted until piglets were weaned on d 21 of lactation.The number of live-born piglets was standardized to 12 tion,body weight of piglets was measured and milk samples±1 per sow on day of parturition.On d 0 and21 of lactawere obtained from sows,and serum samples and feces from piglets were obtained on d 21.Results Feed intake,backfat loss,and weaning estrus interval did not differ among the four groups of sows.Maternalα-GML supplementation increased(P<0.05)the body weight of piglets at weaning and the apparent total tract digestibility of crude fat of sows.The immunoglobulin A and immunoglobulin G levels were greater(P<0.05)in a quadratic manner in the milk of sows as dietaryα-GML increased.Concerning fatty acid profile,C12:0,C15:0,C17:0,C18:2n6c,C18:3n3,C24:0,and C22:6n3 were higher(P<0.05)in linear and quadratic manners in colostrum of sowsfedα-GML diets compared with the control sows.There was lower(P<0.05)n-6:n-3 polyunsaturated fatty acid ratio in milk than in the control sows.Maternalα-GML increased the abundance of Firmicutes(P<0.05)and decreased the abundance of Proteobacteria(P<0.05)of piglet fecal microbiota.Conclusions Dietary supplementation withα-GML improved milk immunoglobulins and altered fatty acids of sows,thereby improving the health of piglets. | Longxian Li Huakai Wang Shuang Dong Yongxi Ma | 2023 | Journal of Animal Science and Biotechnology2023，14，4： | 1 |
| 7 | Efficacy of methionine hydroxy analog and DL-methionine as methionine sources for growing pigs显示文摘 | Zhanyu Feng Shiyan Qiao Yongxi Ma | | 0，，02： | 1 |
| 8 | Endogenous chitinase might lead to differences in growth performance and intestinal health of piglets fed different levels of black soldier fly larva meal显示文摘This study aimed to investigate the effects of different levels of black soldier fly(BSF)replacing soybean meal(SBM)in diets on the performance and health condition of piglets.A total of 180 weaned piglets were allocated into 5 treatments:BSF0(corn-soybean meal basal diet),BSF25(BSF replacing 25%SBM),BSF50(BSF replacing 50%SBM),BSF75(BSF replacing 75%SBM)and BSF100(BSF replacing 100%SBM).During the whole period,in comparison with BSF0,average daily gain(ADG)and average daily feed intake increased in the BSF25 and BSF50 groups,whereas ADG decreased in the BSF75 and BSF100groups(P<0.05).The result of quadratic fitting curve showed that piglets exhibited the highest ADG when BSF replaced around 20%SBM.Compared with BSF0,organic matter and dry matter digestibility improved in the BSF25 group,whereas ether extract digestibility decreased in the BSF100 group(P<0.05).In comparison with BSF0,piglets from the BSF25 group showed a higher duodenal ratio of villus height to crypt depth,increased jejunal sucrase activity,serum neuropeptide Y and ghrelin levels,elevated ileal immunoglobulin(Ig)A,Ig G and Ig M contents and a lower leptin level,and piglets from the BSF100 group exhibited an increased relative weight of kidney(P<0.05).However,no significant differences were observed in the expression level of tight junction proteins and chitin-degrading enzyme.Additionally,compared with BSF0,the abundance of short chain fatty acid producing bacteria such as Ruminococcaceae,Faecalibacterium and Butyricicoccus increased,and potential pathogenic bacteria decreased in piglets from the BSF25 group,whereas piglets from the BSF100 group had a greater abundance of harmful bacteria.In conclusion,BSF replacing 25%SBM in diets could improve digestive parameters,immune function and intestinal microbiota,and thus improved growth performance of piglets.However,BSF replacing 100%SBM showed an adverse effect on piglet performance,and the reason might be related to the limited amount of chitin-degrading enzyme. | Sujie Liu Jian Wang Longxian Li Yonggai Duan Xiaolin Zhang Tenghao Wang Jianjun Zang Xiangshu Piao Yongxi Ma Defa Li | 2023 | Animal Nutrition2023，，3： | 0 |
| 9 | Research on the management models of the rural primary water management from the view of public service:a case study of Zhejiang Province显示文摘The rural primary organizations of water management are the important parts of the public service system in the government administration.This paper studies several major management models of the rural primary water management in Zhejiang Province of China.The research result shows that ambiguous functions,lack of funding,and unreasonable personnel structure are the major problems of the rural primary water management.Therefore,it is urgent to improve service system,ensure sufficient funds,and qualify the population personnel of the rural primary organizations of water | Yongxi Ma Ying Wang Yao Wang | 2014 | Chinese Journal of Population,Resources and Environment2014，12，3： | 0 |
| 10 | Measuring benefits of rural-to-urban water transfer:a case study from Puyang River basin,China显示文摘Agriculture-to-urban water transfer is currently an important measure to meet the increasing water demand resulting from rapid industrialization and urbanization in China.Measuring benefits of agriculture-to-urban water transfer is critical to assess water transfer proposals,and it can also provide reliable basis for redistributing the benefits of agriculture-to-urban water transfer.This paper has developed a comprehensive framework in which production function approach is applied to quantify the value of water use in agricultural and industrial sectors,and contingent valuation method is employed to investigate the value of water use in municipal consumption and ecological environment.A case study from Zhuji City in China verified the feasibility and validity of the method proposed in the paper.Results indicate that the agriculture-to-urban water transfer increases the water value created by improving allocation efficiency of water use in different sectors.The benefits of agriculture-to-urban water transfer mainly originate from the fact that the economic value in industrial water use is higher than in the other sectors’water use.Meanwhile,the urban residents have a stronger desire to improve the water eco-environment which leads to higher water value in urban area. | Juanli Wang Yongxi Ma Alan R.Collins | 2019 | Chinese Journal of Population,Resources and Environment2019，17，4： | 0 |
| 11 | Strategic design of lysine-targeted irreversible covalent NDM-1 inhibitors显示文摘New Delhi metallo-β-lactamase 1(NDM-1) can hydrolyze most β-lactam antibiotics, which is the major factor for drug resistance of Gram-negative bacteria. The binding of most reversible inhibitors to NDM-1 is relatively weak due to the shallow active pocket of NDM-1. Alternatively, irreversible covalent inhibitors can prevent their dissociation from the target, leading to permanent inactivation of the protein.Herein, we report a series of irreversible covalent inhibitors of NDM-1 targeting the conserved Lys211 in the active pocket. Several methods, including mass spectrometry, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, fluorescent labeling, and coumarin probe were used to demonstrate that pentafluorophenyl ester formed a covalent bond with Lys211. Moreover, our target inhibitor, in combination with meropenem, achieved an antibacterial effect on drug-resistant bacteria, along with an excellent safety profile. Our new strategy in designing lysine-targeted irreversible covalent NDM-1 inhibitors provides a potential option for the clinical treatment of Gram-negative bacteria. | Youzhen Ma Yongxi Liang Menglu Guo Delin Min Lulu Zheng Yun Tang Xun Sun | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
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