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| 1 | Association of chronic viral hepatitis B with insulin resistance显示文摘AIM:To investigate the relationship between chronic viral hepatitis B(CVHB) and insulin resistance(IR) in Korean adults.METHODS:A total of 7880 adults(3851 men,4029 women) who underwent a comprehensive medical examination were enrolled in this study.Subjects diagnosed with either diabetes mellitus,or any other disorder that could influence their insulin sensitivity,were rejected.Anthropometry,metabolic risk factors,hepatitis B surface antigen,hepatitis B surface antibody,hepatitis B core antibody,fasting plasma glucose and insulin were measured for all subjects.Homeostasis model assessment(HOMA),quantitative insulin check index(QUICKI),and Mf fm index were used for determining insulin sensitivity.Each participant was categorized into a negative,recovery,or CVHB group.To compare variables between groups,a t-test and/or one-way analysis of variance were used.Partial correlation coefficients were computed to present the association between insulin resistance and other variables.Multiple logistic regression analysis was used to assess the independent association between CVHB and IR.RESULTS:The mean age of men and women were 48.9 and 48.6 years,respectively.Subjects in the CVHB group had significantly higher waist circumference [(86.0 ± 7.7 cm vs 87.3 ± 7.8 cm,P = 0.004 in men),(78.3 ± 8.6 cm vs 80.5 ± 8.5 cm,P < 0.001 in women)],cystatin C [(0.96 ± 0.15 mg/dL vs 1.02 ± 0.22 mg/dL,P < 0.001 in men),(0.84 ± 0.15 mg/dL vs 0.90 ± 0.16 mg/dL,P < 0.001 in women)],fasting insulin [(5.47 ± 3.38 U/mL vs 6.12 ± 4.62 U/mL,P < 0.001 in men),(4.57 ± 2.82 U/mL vs 5.06 ± 3.10 U/mL,P < 0.001 in women)] and HOMA index [(1.24 ± 0.86 vs 1.43 ± 1.24,P < 0.001 in men),(1.02 ± 0.76 vs 1.13 ± 0.87,P = 0.033 in women)] compared to control group.The HOMA index revealed a positive correlation with body mass index(BMI)(r = 0.378,P < 0.001),waist circumference(r =0.356,P < 0.001),percent body fat(r = 0.296,P < 0.001),systolic blood pressure(r = 0.202,P < 0.001),total cholesterol(r = 0.134,P < 0.001),triglycerides(r = 0.292,P < 0.001),cystatin C(r = 0.069,P < 0.001) and uric acid(r = 0.142,P < 0.001).The QUICKI index revealed a negative correlation with BMI(r =-0.254,P < 0.001),waist circumference(r = 0-0.243,P < 0.001),percent body fat(r =-0.217,P < 0.001),systolic blood pressure(r =-0.132,P < 0.001),total cholesterol(r =-0.106,P < 0.001),triglycerides(r =-0.205,P < 0.001),cystatin C(r =-0.044,P < 0.001) and uric acid(r =-0.096,P < 0.001).For subjects identified with IR,the odds ratio of an accompanying diagnosis of chronic hepatitis B was 1.534(95% CI:1.158-2.031,HOMA index criteria) or 1.566(95% CI:1.124-2.182,QUICKI criteria) after adjustment for age,gender,BMI,and amount of alcohol consumption.CONCLUSION:Our study demonstrates that CVHB is associated with IR.CVHB may need to be monitored for occurrence of IR and diabetes mellitus. | Jeong Gyu Lee Sangyeoup Lee Yun Jin Kim Byung Mann Cho Joo Sung Park Hyung Hoi Kim JaeHun Cheong Dong Wook Jeong Yu Hyun Lee Young Hye Cho Mi Jin Bae Eun Jung Choi | 2012 | World Journal of Gastroenterology2012，18，42： | 10 |
| 2 | Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis显示文摘AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.METHODS:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ACD.RESULTS:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan. | Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young Woo Choi Young Woo Kang Woo Suk Chung | 2013 | World Journal of Gastroenterology2013，19，40： | 6 |
| 3 | Overview of the Shenzhen Emergency Medical Service Call Pattern显示文摘BACKGROUND:In Shenzhen,the Emergency Medical Service(EMS) system has been in service since 1997.This study aims to examine the operation of Shenzhen 120 EMS center and to identify the reasons of calling EMS.METHODS:In this retrospective quantitative descriptive study,the data from the Shenzhen 120 EMS registry in 2011 were analyzed.RESULTS:Shenzhen 120 EMS center is a communication command center.When the number of 120 are dialed,it is forwarded to the closest appropriate hospital for ambulance dispatch.In2011,the Shenzhen 120 EMS center received 153 160 ambulance calls,with an average of 420 calls per day.Calling emergency services was mainly due to traffic accidents.Trauma and other acute diseases constituted a majority of ambulance transports.The adult patients aged 15-60 years are the principal users of EMS.There are no recognized 'paramedic' doctors and nurses.The pre-hospital emergency service is under the operation of emergency departments of hospitals.Shenzhen at present does not have specialized pre-hospital training for doctors and nurses in posttrauma management.Moreover,specialized pre-hospital training,financial support,and public health education on proper use of EMS should be emphasized.CONCLUSION:The Shenzhen 120 EMS center has its own epidemiology characteristics.Traumatic injury and traffic accident are the main reasons for calling ambulance service.In-depth study emphasizing the distribution and characteristics of trauma patients is crucial to the future development of EMS. | Shuk Man Lo Yi Min Yu Lap Yip Larry Lee Mi Ling Eliza Wong Sek Ying Chair Edward J Kalinowski Tak Shing Jimmy Chan | 2012 | World Journal of Emergency Medicine2012，3，4： | 4 |
| 4 | Non-invasive assessment of hepatic steatosis: Prospective comparison of the accuracy of imaging examinations显示文摘 | Seung Soo Lee Seong Ho Park Hye Jin Kim So Yeon Kim Min-Yeong Kim Dae Yoon Kim Dong Jin Suh Kang Mo Kim Mi Hyun Bae Joo Yeon Lee Sung-Gyu Lee Eun Sil Yu | 2010 | Journal of Hepatology2010，，4： | 2 |
| 5 | Optimization of microencapsulation of seed oil by response surface methodology显示文摘 | Jang - Hyuk Ahn Young - Pil Kim Yu - Mi Lee | 2008 | Food Chemistry2008，107，1： | 1 |
| 6 | Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers显示文摘 | Yu Wang Yasushi Adachi Arisa Imsumran Hiroyuki Yamamoto Wenhua Piao Hua Li Masanori Ii Yoshiaki Arimura Mi Young Park Dalrae Kim Choon-Taek Lee David P. Carbone Kohzoh Imai Yasuhisa Shinomura | 2010 | Journal of Gastroenterology2010，，2： | 1 |
| 7 | Epidemiology and risk factors of community onset irdections caused by extended- spectrum-lactamase-producing Escherichia coli Strains显示文摘 | Cbeol-In Kang Yu Mi Wi Mi Young Lee | 2012 | Journal of Clinical Microbiology2012，50，2： | 1 |
| 8 | A two dose combined hepatitis A and B vaccine in Chinese youngsters显示文摘 | Lee SD Chan CY Yu MI | 1999 | J Med Virol1999，59，1： | 1 |
| 9 | Wogonin suppresses TNF-α-induced MMP-9 expression by blocking the NF-κB activation via MAPK signaling pathways in human aortic smooth muscle ceils显示文摘 | Syng-Ook Lee Yun-Jeong Jeong Mi Hee Yu etal | 2006 | Biochemical and Biophysical Research Communications2006，351，： | 1 |
| 10 | Inhibitory effect of fractions from skullcap (Scutellaria baicalensis Georgi) on osteoclast differentiation and bone resorption 显示文摘 | Nam Kyung Im Hyo Jung Lee Mi Hee Yu | 2011 | Food Sci- ence and Biotechnology2011，20，5： | 1 |
| 11 | The repressive activity of hepatitis C virus core protein on the transcription of p21 waf1 is regulated by protein kinase A-mediated phosphorylation显示文摘 | Eun Young Jung Mi Nam Lee Hyo Young Yang Dae-Yeul Yu Kyung Lib Jang | 2001 | Virus Research2001，，1： | 1 |
| 12 | Effect of light quality on Bacillus amyloliquefaciens JBC36 and its biocontrol efficacy显示文摘 | Yu Sang mi Lee Yong hoon | 2013 | Biological Control2013，64，： | 1 |
| 13 | Safety and immunogenic ity of inactivated hepatitis A vaccine in patients with chronicliver disease 显示文摘 | Lee SD Chan CY Yu MI | 1997 | J Med Virol1997，52，2： | 1 |
| 14 | Targeting for insulin-like growth factor-I receptor with short hairpin RNA for human digestive/gastrointestinal cancers显示文摘 | Yu Wang Yasushi Adachi Arisa Imsumran Hiroyuki Yamamoto Wenhua Piao Hua Li Masanori Ii Yoshiaki Arimura Mi Young Park Dalrae Kim Choon-Taek Lee David P. Carbone Kohzoh Imai Yasuhisa Shinomura | 2010 | Journal of Gastroenterology2010，，2： | 1 |
| 15 | Aggravation of L-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells 显示文摘 | Jae Joon Lee Yu Mi Kim Shou Yu Yin | 2003 | Biochem Pharmacol2003，66，： | 1 |
| 16 | Risk Factors and Stroke Mechanisms in Atherosclerotic Stroke: Intracranial Compared With Extracranial and Anterior Compared With Posterior Circulation Disease显示文摘 | Jong S. Kim Hyun-Wook Nah Sea Mi Park Su-Kyung Kim Ki Hyun Cho Jun Lee Yong-Seok Lee Jei Kim Sang-Won Ha Eung-Gyu Kim Dong-Eog Kim Dong-Wha Kang Sun U. Kwon Kyung-Ho Yu Byung-Chul Lee | 2012 | Stroke2012，，12： | 1 |
| 17 | A high‐fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity‐resistant BALB/c mice显示文摘 | Heesook Park Minhee Kim Gyoo Taik Kwon Do Young Lim Rina Yu Mi‐Kyung Sung Ki Won Lee James W. Daily Jung Han Yoon Park | 2011 | Mol Carcinog2011，，11： | 1 |
| 18 | Propofol limits rat myocardial ischemia and reperfusion injury with an associated reduction in apoptotic cell death in vivo显示文摘 | Yong Chun Jin WooYeol Kim Yu Mi Ha Il Woo Shin Ju Tae Sohn Hye Jung Kim Han Geuk Seo Jea Heun Lee Ki Churl Chang | 2008 | Vascular Pharmacology2008，，1： | 1 |
| 19 | Up-regulation of Foxo4 mediated by hepatitis B virus X protein confersresistance to oxidative stress-induced cell death显示文摘 | Ratakorn Srisuttee Sang Koh Eun Park Il-Rae Cho Hye Min Byung Jhun Dae-Yeul Yu Sun Park Do Park Mi Lee Diego Castrillon Randal Johnston Young-Hwa Chung | 2011 | International Journal of Molecular Medicine2011，，2： | 1 |
| 20 | Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice显示文摘 | Kyeong-Mi Choi Youn-Sun Lee Wonkyun Kim Seung Jung Kim Kyong-Oh Shin Ji-Yeon Yu Mi Kyeong Lee Yong-Moon Lee Jin Tae Hong Yeo-Pyo Yun Hwan-Soo Yoo | 2013 | The Journal of Nutritional Biochemistry2013，，： | 1 |
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