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| 1 | Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis显示文摘在哺乳动物的精子发生被 piRNA 表示的二个波浪描绘:一个人对应于负责的经典 piRNAs 因为 silencing retrotransponsons 和第二个波浪主要在 pachytene spermatocytes 从 nontransposon intergenic 区域被导出,但是这些 pachytene piRNAs 的功能大部分是未知的。这里,我们在在老鼠伸长指示巨大的 mRNA 消除报导 pachytene piRNAs 的参与 spermatids (ES ) 。我们证明包含鼠科的 PIWI (MIWI ) 和 deadenylase CAF1 的导致 piRNA 的 silencing 建筑群(pi-RISC ) 有选择地在 ES 被装配,它负责经由在体的房间类似于 miRNAs 的行动的机制导致 mRNA deadenylation 和腐烂。如此的一个高度安排的节目看起来充分利用 pachytene piRNAs 的能力从 nontransposon intergenic 区域导出的多样化的指向的庞大的全部剧目。这些调查结果建议 pachytene piRNAs 负责为精子生产作准备,从 ES 使广阔细胞的节目失去活性。 | Lan-Tao Gou Peng Dai Jian-Hua Yang Yuanchao Xue Yun-Ping Hu Yu Zhou Jun-Yan Kang Xin Wang Hairi Li Min-Min Hua Shuang Zhao Si-Da Hu Li-Gang Wu Hui-Juan Shi Yong Li Xiang-Dong Fu Liang-Hu Qu En-Duo Wang Mo-Fang Liu | 2014 | Cell Research2014，24，6： | 39 |
| 2 | MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes显示文摘piRNA 机械在调停以它的角色著名 transposons 的 epigenetic silencing。最近的研究建议这功能也包含导出 transposon 的抄本的指导 piRNA 的劈开。同样多 piRNAs 也看起来有能力指向多样的 mRNAs,这提起 piRNAs 可以与 siRNAs 比广泛地扮演降级的吸引人的可能性特定的 mRNAs。直接测试这个假设,我们比较了联系的老鼠 PIWI (MIWI ) 有从老鼠睾丸的试验性地识别的劈开的 mRNA 碎片的 piRNAs,和主要发生在的观察劈开地点从 5 ′ 放 10;通常认为的指向结束 piRNAs。我们也注意了强壮的偏爱因为分别地,在核苷酸的 U 和 A 残余在 piRNAs 和 mRNA 碎片放 1 和 10,由“乒乓球”类似于 piRNA 扩大的模式的特征骑车。通过由介绍的 CLIP-seq 和基因表示 MIWI-RNA 相互作用印射,我们发现许多潜在的指向 piRNA 的 mRNAs 直接与 MIWI 交往,表演在 Miwi 的睾丸提高了表达式层次催化变异的鼠标。基于记者的试金进一步揭示了在调停 piRNA 的目标压抑的为 slicer 活动和 MIWI 的装载 piRNA 能力的在 piRNAs 和 mRNA 目标和要求之间的基础配对的重要性。重要地,我们证明某些关键 piRNA 目标的那合适的周转为精子形成是必要的。一起,这些调查结果为男细菌房间开发和成熟在鼠标睾丸和它的中央要求揭示 piRNA 机械的象 siRNA 一样函数。 | Peng Zhang Jun-Yan Kang Lan-Tao GOU Jiajia Wang Yuanchao Xue Geir Skogerboe Peng Dai Da-Wei Huang Runsheng Chen Xiang-Dong Fu Mo-Fang Liu Shunmin He | 2015 | Cell Research2015，25，2： | 35 |
| 3 | Responses of ephemeral plant germination and growth to water and heat conditions in the southern part of Gurbantunggut Desert显示文摘在 Gurbantunggut 沙漠的南部的部分的短暂植物系统地从 2002 ~ 2004 被监视,气象学的数据和土壤潮湿在一样的时期期间被分析。结果证明短暂植物萌芽和生长对水和热状况的变化敏感。超过 0 的每日的温度的时间 ????????? | WANG Xueqing JIANG Jin WANG Yuanchao LUO Weilin SONG Chunwu CHEN Junjie | 2006 | Chinese Science Bulletin2006，51，A01： | 19 |
| 4 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 5 | Selective separation of protein and saccharides by ionic liquids aqueous two-phase systems显示文摘In the present work,it was found that aqueous solution of a hydrophilic ionic liquid (IL),1-butyl-3-methylimidazolium dicyanamide ([C4mim][N(CN)2]),could be separated into an aqueous two-phase system (ATPS) by inorganic salts such as K2HPO4 and K3PO4.The top phase is IL-rich,while the bottom phase is phosphate-rich.It was shown that 82.7%-100% bovine serum albumin (BSA) could be enriched into the top phase and almost quantitative saccharides (arabinose,glucose,sucrose,raffinose or dextran) were preferentially extracted into the bottom phase in a single-step extraction by [C4mim][N(CN)2] + K2HPO4 ATPS.The extraction efficiency of BSA from the aqueous saccharide solutions was influenced by the molecular structure of saccharides.The conductivity,dynamic light scattering (DLS) and transmission electron microscopy (TEM) were combined to investigate the microstructure of the IL-rich top phase and the possible mechanism for the selective separation.It is suggested that the formation of the IL aggregate and the IL aggregate-BSA complex plays a significant role in the separation of BSA from aqueous saccharide solutions.This is the first example for the selective separation by ILs-based ATPSs.It is expected that these findings would have potential applications in bio-analysis,separation,and IL recycle. | PEI YuanChao LI ZhiYong LIU Li WANG JianJi WANG HuiYong | 2010 | Science China Chemistry2010，53，7： | 12 |
| 6 | Phytophthora sojae Effector PsAvh240 Inhibits Host Aspartic Protease Secretion to Promote Infection显示文摘Plants secrete defense molecules into the extracellular space (the apoplast) to combat attacking microbes. However, the mechanisms by which successful pathogens subvert plant apoplastic immunity remain poorly understood. In this study, we show that PsAvh240, a membrane-localized effector of the soybean pathogen Phytophthora sojae, promotes P. sojae infection in soybean hairy roots. We found that PsAvh240 interacts with the soybean-resistant aspartic protease GmAP1 in planta and suppresses the secretion of GmAP1 into the apoplast. By solving its crystal structure we revealed that PsAvh240 contain six a helices and two WY motifs. The first two a helices of PsAvh240 are responsible for its plasma membrane-localization and are required for PsAvh240's interaction with GmAP1. The second WY motifs of two PsAvh240 molecules form a handshake arrangement resulting in a handshake-like dimer. This dimerization is required for the effector's repression of GmAP1 secretion. Taken together, these data reveal that PsAvh240 localizes at the plasma membrane to interfere with GmAP1 secretion, which represents an effective mechanism by which effector proteins suppress plant apoplastic immunity. | Baodian Guo Haonan Wang Bo Yang Wenjing Jiang Maofeng Jing Haiyang Li Yeqiang Xia Yuanpeng Xu Qinli Hu Fangfang Wang Feng Yu Yan Wang Wenwu Ye Suomeng Dong Weiman Xing Yuanchao Wang | 2019 | Molecular Plant2019，12，4： | 12 |
| 7 | Design and development of an oral remdesivir derivative W116 against SARS-CoV-2显示文摘Dear Editor,Since the declaration of COVID-19 as a global pandemic on March 11,2020,this pandemic has been circulating for 17 months throughout the world,leading to more than 200 million infections and nearly 4.4 million deaths as of August 15,2021.The pathogen of COVID-19 is a novel coronavirus named SARS-CoV-2,which shares-79%genome sequence identity with SARS-CoV.1 At the early stage of the COVID-19 outbreak,5ARS-CoV-2 caused great panic in the hardest-hit areas due to its high transmissibility and pathogenicity.To fight the COVID-19 crisis,drug repurposing was immediately pursued in order to find potential therapeutics. | Yuanchao Xie Wanchao Yin Yumin Zhang Weijuan Shang Zhen Wang Xiaodong Luan Guanghui Tian Haji A.Aisa Yechun Xu Gengfu Xiao Jia Li Hualiang Jiang Shuyang Zhanq Leike Zhang H.Eric Xu Jingshan Shen | 2021 | Cell Research2021，31，11： | 12 |
| 8 | Emerging roles of non-coding RNAs in epigenetic regulation显示文摘Recent deep sequencing surveys of mammalian genomes have unexpectedly revealed pervasive and complex transcription and identified tens of thousands of RNA transcripts that do not code for proteins. These non-coding RNAs(nc RNAs) highlight the central role of RNA in gene regulation. nc RNAs are arbitrarily divided into two main groups: The first includes small RNAs, such as mi RNAs, pi RNAs, and endogenous si RNAs, that usually range from 20 to 30 nt, while the second group includes long non-coding RNAs(lnc RNAs), which are typically more than 200 nt in length. These nc RNAs were initially thought to merely regulate gene expression at the post-transcriptional level, but recent studies have indicated that nc RNAs, especially lnc RNAs, are extensively associated with diverse chromatin remodeling complexes and target them to specific genomic loci to alter DNA methylation or histone status. These findings suggest an emerging theme of nc RNAs in epigenetic regulation. In this review, we discuss the wide spectrum of nc RNAs in the regulation of DNA methylation and chromatin state, as well as the key questions that needs to be investigated and acknowledging the elegant design of these intriguing macromolecules. | Juan Chen Yuanchao Xue | 2016 | Science China(Life Sciences)2016，59，3： | 11 |
| 9 | Main deposit styles and associated tectonics of the West Junggar region,NW China显示文摘The West Junggar region,located in the loci of the Central Asian Orogenic Belt,is a highly endowed metallogenic province with >100 tonnes Au,>0.7 Mt Cu,>0.3 Mt Mo,and >2.3 Mt chromite as well as significant amounts of Be and U.The West Junggar region has three metallogenic belts distributed systematically from north to south:(1) late Paleozoic Saur Au-Cu belt;(2) early Paleozoic XiemisitaiSharburt Be-U-Cu-Zn belt;(3) late Paleozoic Barluk-Kelamay Au-Cu-Mo-Cr belt.These belts host a number of deposits belonging to at least eight economically important styles,including epithermal Au,granite-related Be-U,volcanogenic massive sulfide(VMS) Cu-Zn,podiform chromite,porphyry Cu,hydrothermal quartz vein Au,porphyry-greisen Mo(-W),and orogenic Au.These deposit styles are associated with the tectonics prevalent during their formation.Five tectonic-mineralized epochs can be recognized:(1) Ordovician subduction-related VMS Cu-Zn deposit;(2) Devonian ophiolite-related podiform chromite deposit;(3) early Carboniferous subduction-related epithermal Au and porphyry Cu deposits;(4) late Carboniferous subduction-related granite-related Be-U,porphyry Cu,and hydrothermal quartz vein Au deposits;and(5) late Carboniferous to early Permian subduction-related porphyry-greisen Mo(-W) and orogenic Au deposits. | Ping Shen Hongdi Pan Yuanchao Shen Yuhong Yan Shihua Zhong | 2015 | Geoscience Frontiers2015，6，2： | 8 |
| 10 | Intracellular and Extracellular Phosphatidylinositol 3-Phosphate Produced by Phytophthora Species Is Important for Infection显示文摘Phytophthora 病原体生产的 RxLR 受动器被建议了把 3 磷酸盐(PtdIns (3 ) P ) 绑在 phosphatidylinositol 调停他们的 translocation 进主人房间或到增加他们在 planta 的稳定性。因为在植物的 PtdIns (3 ) P 的层次是低的,我们检验了 Phytophthora 种类是否可以生产 PtdIns (3 ) 支持感染的 P。我们观察了 P 特定的 GFP 生物传感器能绑在 P 的那 PtdIns (3 ) 。parasitica 和 P。sojae hyphae 短暂地在 Nicotiana benthamiana 的感染期间离开 secreting 生物传感器,建议 hyphae 暴露了 PtdIns (3 ) 他们的血浆膜上的 P 或分泌 PtdIns (3 ) P。phosphatidylinositol 3-kinases (PI3K ) 的 Silencing 基因,有 LY294002 的处理,或 PtdIns (3 ) 的表示由 P 的 P 有约束力的蛋白质。sojae 在大豆上减少了病原体的毒力,显示综合病原体的 PtdIns (3 ) P 为完整的毒力被要求。PtdIns (3 ) 的分泌物 P 有约束力的蛋白质或由 N 的 PI3P-5-kinase。benthamiana 叶子显著地由 P 增加了抵抗的水平到感染。parasitica 和 P。capsici。一起,我们的结果支持假设那 Phytophthora 种生产外部 PtdIns (3 ) 帮助感染的 P,例如支持 RxLR 受动器的入口进宿主细胞。我们的结果源于 P。sojae RxLR 受动器 Avr1b 证实 N 终点和这个受动器的 C 终点能绑 PtdIns (3 ) P。 | Shan Lu | 2013 | Molecular Plant2013，6，5： | 7 |
| 11 | Effects of Bacterial-Feeding Nematode Grazing and Tea Saponin Addition on the Enhanced Bioremediation of Pyrene-Contaminated Soil Using Polycyclic Aromatic Hydrocarbon-Degrading Bacterial Strain显示文摘As one of the most widely distributed bacterial predators in the soil, the role of bacterivorous nematodes on the enhanced bioremediation of polycyclic aromatic hydrocarbon-contaminated soils is crucial, but remains to be investigated.A microcosm-level study was conducted to examine the effects of bacterial-feeding nematode grazing and tea saponin(TS) addition on bioremediation of a pyrene-contaminated soil enhanced by the polycyclic aromatic hydrocarbon(PAH)-degrading bacterial strain Sphingobium sp.PHE9.After 180 d of incubation, the highest pyrene dissipation(71.3%) was achieved through a combination of Sphingobium sp.PHE9 inoculation with nematode and TS addition.Meanwhile, high counts of culturable PAH-degrading bacteria, soil enzyme activity, and biodiversity indices were observed under the combined treatment, implying that the microbiological function of the contaminated soil was significantly restored.Additionally, the results of Tenax~ extraction with the first-order three-compartment model indicated that rate-limiting factors varied among treatments.The lack of degrading microorganisms was the main rate-limiting factor for the treatments involving TS/nematode addition, and inadequate bioaccessible pyrene was the vital rate-limiting factor in the treatments involving Sphingobium sp.PHE9 inoculation.The proposed combined clean-up strategy proved to be a promising bioremediation technology for aged pyrene-contaminated soils. | SUN Mingming LIU Kuan ZHAO Yuanchao TIAN Da YE Mao LIU Manqiang JIAO Jiaguo JIANG Xin | 2017 | Pedosphere2017，27，6： | 7 |
| 12 | Noncoding RNA:from dark matter to bright star显示文摘The central dogma states that genes encoded in the DNA should be first transcribed into messenger RNA(mRNA)and then translated into functional proteins(Crick,1970).This dogma has been written in numerous textbooks and learned by myriad students.However,along with the completion of the human genome project in June 2000,an astonishing fact was revealed:only 1.5%of the human genome encodes for proteins(Lander et al.,2001;Venter et al.,2001).This fact raised three fundamental questions:(i)why does the human genome have so few protein-coding genes?(ii)how to explain the apparent differences between humans and other species using the limited coding genes?(iii)what are the roles of the noncoding regions in our genome? | Yuanchao Xue Runsheng Chen Lianghu Qu Xiaofeng Cao | 2020 | Science China(Life Sciences)2020，63，4： | 6 |
| 13 | Performance of ecological restoration in an impaired coral reef in the Wuzhizhou Island, Sanya, China显示文摘Coral restoration is becoming popular to help restoring degraded coral reefs.However,few studies have tried to monitor the long-term recovery of coral reefs,which makes it diffi cult to assess the performance of the restoration.We monitored the growth of three transplanted Acropora corals and naturally-attached Pocillopora damicornis on artifi cial reefs(ARs)from October 2014 to September 2018 during which there were several attacks of typhoons.Results show that two staghorn Acropora species had the highest growth rates(11.0–12.1 cm/a),followed by table coral A.divaricate(5.6 cm/a)and P.damicornis(4.8 cm/a).A linear growth pattern was found for the three Acropora species;the pattern gradually slowed in P.damicornis.There was a strong interspecifi c competition for space among the corals on ARs,and it led to the sharply declined occurrence of slow-growing P.darmicornis colonies in 2017.Coral recovery was successful at the Wuzhizhou Island and quickly increased AR complexity.However,the ARs made of metal frames fail to resist the direct attack from a catastrophic typhoon.Therefore,concrete and environmentalfriendly materials should be used in future restoration.This study is the fi rst report on long-term monitoring and assessment of coral reef restoration in China.The results off er future guide of reef restoration for impaired coral reefs in regions easily aff ected by typhoons. | Xinqing ZHENG Yuanchao LI Jilin LIANG Rongcheng LIN Daoru WANG | 2021 | Journal of Oceanology and Limnology2021，39，1： | 6 |
| 14 | A new distinct geminivirus causes soybean stay-green disease显示文摘Dear Editor,Plant viruses make up almost half of the plant disease-causing pathogens,affecting crop yields and the global economy(Savary et al.,2019).Soybean(Glycine max)is one of the most valuable legume crops in the world,supplying 25%of the global edible oil and two-thirds of the global concentrated protein for livestock feeding.Recently,the outbreak of soybean stay-green syndrome with delayed leaf senescence(stay-green),flat pods,and increased number of abnormal seeds has swept the soybean production in the Huang-Huai-Hai region of China,resulting in huge yield losses(Xu et al.,2019).This disease has become an epidemic and prominent problem in soybean production and is still expanding its geography,including North America,posing a serious threat to soybean production(Harbach et al.,2016;Zhang et al.,2016;Li et al.,2019).However,the cause of soybean stay-green syndrome remains obscure. | Ruixiang Cheng Ruoxin Mei Rong Yan Hongyu Chen Dan Miao Lina Cai Jiayi Fan Gairu Li Ran Xu Weiguo Lu Yu Gao Wenwu Ye Shuo Su Tianfu Han Junyi Gai Yuanchao Wang Xiaorong Tao Yi Xu | 2022 | Molecular Plant2022，15，6： | 6 |
| 15 | In vitro and in vivo biocompatibility of Mg–Zn–Ca alloy operative clip显示文摘At present,titanium(Ti)and its alloys are most commonly use in hemostasis clip clinical applications.However,the Ti Clip cannot be absorbed in human body and produce artifacts on computed tomography(CT),and induce clinically relevant hypersensitivity in patients.In order to overcome the drawbacks of the non-degradable Ti clips,an Mg-Zn-Ca alloy operative clip was fabricated by combining hot extrusion and blanking processing.In vitro and in vivo biocompatibility of Mg-Zn-Ca alloy operative clip were evaluated by L-929 Cells and SD rat model respectively.It was found that Mg-Zn-Ca alloy exhibited non-cytotoxic to L929 cells.In vivo implantation showed that the newly designed Mg-Zn-Ca clip can successfully ligated carotid artery and no blood leakage occurred post-surgery.During the period of the clip degradation,a small amount of H2 gas formation and no tissue inflammation around the clips were observed.The degradation rate of the clip near the heart ligated the arteries faster than that of clip far away the heart due do the effect of arterial blood.Histological analysis and various blood biochemical parameters in rat serum samples collected at different times after clip implantation showed no tissue inflammation around the clips. | Pengfei Ding Yuanchao Liu Xianghui He Debao Liu Minfang Chen | 2019 | Bioactive Materials2019，4，1： | 5 |
| 16 | Thermal stability of LiFePO_4/C-LiMn_2O_4 blended cathode materials显示文摘Safety is important to lithium ion battery materials. The thermal stability of LiFePO_4/C-LiMn_2O_4 blended cathode materials is characterized by using TG, XRD, and SEM etc. The results show that LiFePO_4/C-LiMn_2O_4 possesses a worse thermal stability than pure spinel LiMn_2O_4 and pure olivine LiFePO_4/C. When LiFePO_4/C-LiMn_2O_4 blended cathode materials are sintered at 500°C under Ar atmosphere, the sintered cathode materials emit O_2, and appear impurity phases(Li_3PO_4, Fe_2O_3, Mn_3O_4). It is deduced that some chemical reactions take place between different materials, which leads to a worse discharge specific capacity. LiFePO_4/C-LiMn_2O_4 blended cathode materials, therefore, need to be managed and controlled strictly for the sake of thermal stability and safety. | DU YuanChao HUANG XiaoPeng ZHANG KeYu LIANG Feng LI QiuXia YAO YaoChun DAI YongNian | 2017 | Science China(Technological Sciences)2017，60，1： | 5 |
| 17 | Large chromosomal segment deletions by CRISPR/LbCpf1-mediated multiplex gene editing in soybean显示文摘The creation of new soybean varieties has been limited by genomic duplication and redundancy.Efficient multiplex gene editing and large chromosomal segment deletion through clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein(Cas)systems are promising strategies for overcoming these obstacles.CRISPR/Cpf1 is a robust tool for multiplex gene editing.However,large chromosomal excision mediated by CRISPR/Cpf1 has been reported in only a few non-plant species.Here,we report on CRISPR/LbCpf1-induced large chromosomal segment deletions in soybean using multiplex gene targeting.The CRISPR/LbCpf1 system was optimized for direct repeat and guide RNA lengths in crispr RNA(crRNA)array.The editing efficiency was evaluated using LbCpf1 driven by the CaMV35S and soybean ubiquitin promoter.The optimized system exhibited editing efficiencies of up to 91.7%.Our results showed eight gene targets could be edited simultaneously in one step when a single eight-gRNA-target crRNA array was employed,with an efficiency of up to 17.1%.We successfully employed CRISPR/LbCpf1 to produce small fragments(<1 Kb)and large chromosomal segment deletions(10 Kb-1 Mb)involving four different gene clusters in soybean.Together,these data demonstrate the power of the CRISPR/LbCpf1 platform for multiplex gene editing and chromosomal segment deletion in soybean,supporting the use of this technology in both basic research and agricultural applications. | Kaixuan Duan Yuanyuan Cheng Jing Ji Chenchen Wang Yongshu Wei Yuanchao Wang | 2021 | Journal of Integrative Plant Biology2021，63，9： | 5 |
| 18 | Phytophthora Effectors Modulate Genome-wide Alternative Splicing of Host mRNAs to Reprogram Plant Immunity显示文摘Alternative splicing(AS)of pre-mRNAs increases transcriptome and proteome diversity,regulates gene expression through multiple mechanisms,and plays important roles in plant development and stress responses.However,the prevalence of genome-wide plant AS changes during infection and the mechanisms by which pathogens modulate AS remain poorly understood.Here,we examined the global AS changes in tomato leaves infected with Phytophthora infestans,the infamous Irish famine pathogen.We show that more than 2000 genes exhibiting significant changes in AS are not differentially expressed,indicating that AS is a distinct layer of transcriptome reprogramming during plant-pathogen interactions.Furthermore,our results show that P.infestans subverts host immunity by repressing the AS of positive regulators of plant immunity and promoting the AS of susceptibility factors.To study the underlying mechanism,we established a luminescence-based AS reporter system in Nicotiana benthamiana to screen pathogen effectors modulating plant AS.We identified nine splicing regulatory effectors(SREs)from 87 P.infestans effectors.Further studies revealed that SRE3 physically binds U1-70K to manipulate the plant AS machinery and subsequently modulates AS-mediated plant immunity.Our study not only unveils genome-wide plant AS reprogramming during infection but also establishes a novel AS screening tool to identify SREs from a wide range of plant pathogens,providing opportunities to understand the splicing regulatory mechanisms through which pathogens subvert plant immunity. | Jie Huang Xinyu Lu Hongwei Wu Yuchen Xie Qian Peng Lianfeng Gu Juyou Wu Yuanchao Wang Anireddy SNReddy Suomeng Dong | 2020 | Molecular Plant2020，13，10： | 4 |
| 19 | PTB/nPTB: master regulators of neuronal fate in mammals显示文摘 | Jing Hu Hao Qian Yuanchao Xue Xiang-Dong Fu | 2018 | Biophysics Reports2018，4，4： | 4 |
| 20 | The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes显示文摘 | Juan Chen Zhaokui Cai Meizhu Bai Xiaohua Yu Chao Zhang Changchang Cao Xihao Hu Lei Wang Ruibao Su Di Wang Yingpeng Yao Rong Ye Baidong Hou Yang Yu Shuyang Yu Jinsong Li Yuanchao xue | 2018 | Cell Research2018，28，10： | 4 |
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