|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Magnetism parameters characteristics of drilling deposits in Jianghan Plain and indication for forming of the Yangtze River Three Gorges显示文摘The forming time of the Yangtze River Three Gorges is considered as one of keys in the research on the Yangtze River,also is one of the most disputed hotspots.In order to solve the difficult problem,the authors adopt the internationally recognized thoughts and methods of substance tracing from source to sink.The lithologic characteristics,magnetic parameters and magnetic mineral characteristics of deposits in 2 bores are analyzed,which are both sampled from the sedimentary center of the Jianghan Plain.The results are as follows:At about 110 m depth of the core,the contents of coarse materials and stable magnetic mineral both increase significantly.Meanwhile,the magnetic susceptibility of sediment,saturation isothermal remanent magnetization and magnetic susceptibility values of anhysteretic remanent magnetism increase suddenly,which all reflect that at about 110 m depth,the important adjustment has appeared in water system of the Jianghan Plain,and the sedimentary environment and material composition have changed greatly.And it may be the horizon where the Yangtze River Three Gorges formed,its forming time reflected by the paleomagnetic dating is between 1.17 and 1.12Ma B.P. | ZHANG YuFen LI Chang'An WANG QiuLiang CHEN Liang Ma YongFa KANG ChunGuo | 2008 | Chinese Science Bulletin2008，53，4： | 34 |
| 2 | Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide显示文摘 | Sun Ling Sun Shuo Li Yufen Pan Wei Xie Yumei Wang Shushui Zhang Zhiwei | 2014 | Chinese Medical Journal2014，，5： | 13 |
| 3 | The response of annual runoff to the height change of the summertime 0℃ level over Xinjiang显示文摘According to climate features and river runoff conditions,Xinjiang could be divided into three research areas:The Altay-Tacheng region,the Tianshan Mountain region and the northern slope of the Kunlun Mountains.Utilizing daily observations from 12 sounding stations and the annual runoff dataset from 34 hydrographical stations in Xinjiang for the period 1960-2002,the variance of the summertime 0℃ level height and the changing trends of river runoff are analyzed both qualitatively and quantitatively,through trend contrast of curves processed by a 5-point smoothing procedure and linear correlation.The variance of the summertime 0℃ level height in Xinjiang correlates well with that of the annual river runoff,especially since the early 1990s,but it differs from region to region,with both the average height of the 0℃ level and runoff quantity significantly increasing over time in the Altay-Tacheng and Tianshan Mountain regions but decreasing on the northern slope of the Kunlun Mountains.The correlation holds for the whole of Xinjiang as well as the three individual regions,with a 0.01 significance level.This indicates that in recent years,climate change in Xinjiang has affected not only the surface layer but also the upper levels of the atmosphere,and this raising and lowering of the summertime 0℃ level has a direct impact on the warming and wetting process in Xinjiang and the amount of river runoff.Warming due to climate change increases the height of the 0℃ level,but also speeds up,ice-snow melting in mountain regions,which in turn increases river runoff,leading to a season of plentiful water instead of the more normal low flow period. | ZHANG Guangxing SUN Shufang MA Yufen ZHAO Ling | 2010 | Journal of Geographical Sciences2010，20，6： | 10 |
| 4 | A 3rd Order WENO GLM-MHD Scheme for Magnetic Reconnection显示文摘A new numerical scheme of 3rd order Weighted Essentially Non-Oscillatory (WENO) type for 2.5D mixed GLM-MHD in Cartesian coordinates is proposed. The MHD equations are modified by combining the arguments as by Dellar and Dedner et al to couple the divergence constraint with the evolution equations using a Generalized Lagrange Multiplier (GLM). Moreover, the magnetohydrodynamic part of the GLM-MHD system is still in conservation form. Meanwhile, this method is very easy to add to an existing code since the underlying MHD solver does not have to be modified. To show the validation and capacity of its application to MHD problem modelling, interaction between a magnetosonic shock and a denser cloud and magnetic reconnection problems are used to verify this new MHD code. The numerical tests for 2D Orszag and Tang's MHD vortex, interaction between a magnetosonic shock and a denser cloud and magnetic reconnection problems show that the third order WENO MHD solvers are robust and yield reliable results by the new mixed GLM or the mixed EGLM correction here even if it can not be shown that how the divergence errors are transported as well as damped as done for one dimensional ideal MHD by Dedner et al. | FENG Xueshang ZHOU Yufen HU Yanqi | 2006 | 空间科学学报2006，26，1： | 9 |
| 5 | Long-term trends in fog and boundary layer characteristics in Tianjin,China显示文摘Long-term trends in fog episodes,vertical variations of atmospheric boundary structure,and air pollutant concentrations during two different heavy fog events in the Tianjin area were analyzed.The total amount of fog has increased since 1980 due to the stability of the boundary layer and an increase of pollutant emissions.The variation in the characteristics of the boundary layer and air pollutant concentrations were significantly different between the two fog processes(fog 1 and fog II).The onset of fog I was accompanied by a temperature inversion in the low atmosphere,and the average kinetic energy showed a clear diurnal trend and vertical variation,which increased with height.The dissipation of fog I was mainly due to turbulence.However,the atmospheric stratification was not stable in the lower layer before the onset of fog II.The diurnal and vertical changes in kinetic energy were very small,in which turbulent momentum at each measurement height tended to be zero.In the dissipation process of fog II,wind speed increased significantly.Surface PM_(2.)5 concentrations decreased,but the ratio of PM_(2.5) to PM_(10)increased from 0.66 to 0.82 until fog I dissipated.However,the concentration of PM2.5 did not decrease at the early stage of fog II,but the ratio of PM_(2.5) to PM_(10) PM_(2.5)/PM_(10) decreased to 0.21 when fog II dissipated.This study showed that there was a clear difference in the evolution of pollutant concentration for different pollutants and in different developing stages during the fog events.PM2.5 concentration accumulated faster than those of SO_2 and NO_x,and the PM_(2.5) cumulative rate was greater in the mid-term of the fog process. | Suqin Han Ziying Cai Yufen Zhang Jiao Wang Qing Yao Peiyan Li Xiangjin Li | 2015 | Particuology2015，13，3： | 7 |
| 6 | An individualized immune signature of pretreatment biopsies predicts pathological complete response to neoadjuvant chemoradiotherapy and outcomes in patients with esophageal squamous cell carcinoma显示文摘No clinically available biomarkers can predict pathological complete response(pCR)for esophageal squamous cell carcinomas(ESCCs)with neoadjuvant chemoradiotherapy(nCRT).Considering that antitumor immunity status is an important determinant for nCRT,we performed an integrative analysis of immune-related gene profiles from pretreatment biopsies and constructed the first individualized immune signature for pCR and outcome prediction of ESCCs through a multicenter analysis.During the discovery phase,14 differentially expressed immune-related genes(DEIGs)with greater than a twofold change between pCRs and less than pCRs( | Chaoqi Zhang Guochao Zhang Nan Sun Zhen Zhang Liyan Xue Zhihui Zhang Haijun Yang Yuejun Luo Xiaoli Zheng Yonglei Zhang Yufen Yuan Ruixue Lei Zhaoyang Yang Bo Zheng Le Wang Yun Che Feng Wang Sihui Wang Shugeng Gao Qi Xue Yi Zhang Jie He | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 7 |
| 7 | The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent显示文摘P2X7 受体的激活导致阳离子的快速的、双向流动,引起包括 cytotoxicity 的生物回答的宽广范围。然而,调停 P2X7 的 cytotoxicity 的机制仍然保持大部分未经勘探。在我们的以前的学习,在正常条件下面的调停 P2X7 的钙反应的缺乏在 P2X7+ 造血的房间线被发现。在这研究,在房间的不同类型的调停 P2X7 的 cytotoxicity (P2X7 ? ,有钙反应的 P2X7+ ,和没有钙反应的 P2X7+) 被调查。我们的结果证明 P2X7 收缩筋,腺苷 5-triphosphate ( ATP )或2,3-O-( 4 benzoylbenzoyl )-ATP, dose-dependently 在测试的所有P2X7+房间减少了房间生存能力,包括为 调停P2X7 的钙反应否定的 J6-1 , LCL ,和 Namalva 房间,尽管这些效果比在有正常 P2X7 功能的 KG1a 房间观察的那些低。细胞毒素的效果能被 P2X7 对手,氧化 ATP 和 1- 堵住[N, O 二度(5-isoquinolinesulfonyl )-N-methyl-l-tyrosyl]-4-phenylpiperazine。另外, phosphatidylserine 的外表表现能以一种时间依赖者方式和 apoptotic 被检测词法变化能在 J6-1 房间在 P2X7 受体的激活以后被观察。而且,调停 P2X7 的毛孔形成能在低离子的条件下面,然而并非在低二价的条件下面在 KG1a 和 J6-1 房间被检测。这些效果不能在 P2X7 被观察吗?Ramos 房间。这些结果建议 P2X7 调停受体的细胞毒素的效果可以发生独立于钙反应。 | Xiujun Zhang Lijun Meng Baoling He Jing Chen Peng Liu Jie Zhao Yufen Zhang Ming Li Dong An | 2009 | Acta Biochimica et Biophysica Sinica2009，41，5： | 7 |
| 8 | Nitrogen pollution and source identification of urban ecosystem surface water in Beijing显示文摘 | Yufen REN Zhiwei XU Xinyu ZHANG Xiaoke WANG Xiaomin SUN D. J. BALLANTINE Shengzhong WANG | 2014 | Frontiers of Environmental Science & Engineering2014，8，1： | 6 |
| 9 | Improving Tribological Performance of Gray Cast Iron by Laser Peening in Dynamic Strain Aging Temperature Regime显示文摘A high and stable brake disc friction coefficient is needed for automobile safety, while the coefficient degrades due to elevated temperature during the braking process. There is no better solution except changes in material composition and shape design optimization. In the dynamic strain aging(DSA) temperature regime of gray cast iron, micro-dimples with different dimple depth over diameter and surface area density are fabricated on the material surface by laser peening(LP) which is an LST method. Friction behavior and wear mechanism are investigated to evaluate the effects of surface texturing on the tribological performance of specimens under dry conditions. Through LP impacts assisted by DSA, the friction coefficients of the LPed specimens increase noticeably both at room temperature and elevated temperature in comparison to untreated specimens. Moreover, the coefficient of specimen with dimple depth over diameter of 0.03 and surface area density of 30% is up to 0.351 at room temperature, which dramatically rises up to 1.33 times that of untextured specimen and the value is still up to 0.3305 at 400℃ with an increasing ratio of 35% compared to that of untreated specimen. The surface of textured specimen shows better wear resistance compared to untreated specimen. Wear mechanism includes adhesive wear, abrasive wear and oxidation wear. It is demonstrated that LP assisted by DSA can substantially improve wear resistance, raise the friction coefficient as well as its stability of gray cast iron under elevated temperatures. Heat fade and premature wear can be effectively relieved by this surface modification method. | FENG Xu ZHOU Jianzhong MEI Yufen HUANG Shu SHENG Jie ZHU Weili | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 5 |
| 10 | Vertical characteristics and source identification of PM_(10) in Tianjin显示文摘Ambient PM 10 (particulate matter with a diameter less than 10μm) concentrations were measured on a 255 meter tower in Tianjin,China.The samples were collected at four vertical levels (10,40,120 and 220 m).Vertical characteristics for PM 10 samples were studied.The results showed that the concentrations of PM 10 and constituent species had a negative correlation with the sampling height.The highest concentrations of PM 10 and species were obtained at the 10 m level,and the lowest concentrations were measured at the 220 m level.For the fractions of species to total mass,SO 4 2- and NO 3- had higher values (fraction) at greater height;while Ca had a higher fraction at lower height.Possible source categories for the PM 10 ambient dataset were identified by the principal component analysis method.The possible source categories included crustal dust,vehicles,cement dust,and incineration as well as secondary sulfate and nitrate sources.Analysis of meteorological factors on PM 10 concentrations indicated that wind speed and inversion may be the main factors contributing to different concentrations of PM 10 at different heights. | Zhimei Xiao Jianhui Wu Suqin Han Yufen Zhang Hong Xu Xiaoyong Zhang Guoliang Shi Yinchang Feng | 2012 | Journal of Environmental Sciences2012，24，1： | 5 |
| 11 | HIV Prevention and Health Poverty Alleviation-Liangshan Prefecture,Sichuan Province,China,2017-2020显示文摘BACKGROUND Liangshan,officially the Liangshan Yi Autonomous Prefecture,is an autonomous prefecture occupying much of the southern portion of Sichuan Province.It has been a remote and deeply impoverished area and also has the largest population of ethnic Yi people in China(1).For many years,due to geographical environment conditions,traffic conditions,and other historic restrictions,the human immunodeficiency virus(HIV)epidemic in Liangshan Prefecture has become the focus of HIV prevention and control in China since the first acquired immunodeficiency syndrome(AIDS)case was reported in this area in 1995(2-3). | Zhongfu Liu Xuefeng Tang Yufen Liu Linglin Zhang Yihui Yang Yongli Zheng Weixin Liu Chunnong Jike Hong Mai Heying Fan Gang Yu Mengjie Han George F.Gao | 2021 | China CDC weekly2021，3，48： | 4 |
| 12 | Relationships Between River Water Quality and Landscape Factors in Haihe River Basin, China: Implications for Environmental Management显示文摘River water plays a key role in human health, and in social and economic development, and is often affected by both natural factors and human activities. An in-depth understanding of the role of these factors can help in developing an effective catchment management strategy to protect precious water resources. This study analyzed river water quality, patterns of terrestrial and riparian ecosystems, intensity of agricultural activities, industrial structure, and spatial distribution of pollutant emissions in the Haihe River Basin in China for the year of 2010, identifying the variables that have the greatest impact on river water quality. The area percentage of farmland in study area, the percentage of natural vegetation cover in the 1000-m riparian zone, rural population density, industrial Gross Domestic Product(GDP)/km^2, and industrial amino nitrogen emissions were all significantly correlated with river water quality(P < 0.05). Farming had the largest impact on river water quality, explaining 43.0% of the water quality variance, followed by the coverage of natural vegetation in the 1000-m riparian zone, which explained 36.2% of the water quality variance. Industrial amino nitrogen emissions intensity and rural population density explained 31.6% and 31.4% of the water quality variance, respectively, while industrial GDP/km^2 explained 26.6%. Together, these five indicators explained 67.3% of the total variance in water quality. Consequently, water environmental management of the Haihe River Basin should focus on adjusting agricultural activities, conserving riparian vegetation, and reducing industrial pollutant emissions by optimizing industrial structure. The results demonstrate how human activities drive the spatial pattern changes of river water quality, and they can provide reference for developing land use guidelines and for prioritizing management practices to maintain stream water quality in a large river basin. | XU Huashan ZHENG Hua CHEN Xiaoshu REN Yufen OUYANG Zhiyun | 2016 | Chinese Geographical Science2016，26，2： | 4 |
| 13 | N-phosphoryl amino acid models for P–N bonds in prebiotic chemical evolution显示文摘Post-translational modification of proteins by N-phosphorylation of the basic amino acid residues plays important roles in biological processes. The high-energy P–N bond might have contributed to the evolution of prebiotic chemistry. N-phosphoryl amino acids(PAAs) can serve as interesting small molecular models for the study of P–N bonds in prebiotic chemical evolution. PAAs are capable of simultaneously producing several important biomolecules such as polypeptides and oligonucleotides under mild reaction conditions. In this review, we describe the chemistry of PAAs, discusse their likely prebiotic origins and their reactivity and how they relate to biological P–N bond species. We also depict a possible prebiotic scenario mediated by PAAs in which PAAs may have acted as one of the essential forces driving prebiotic biomolecules to the first protocell. | Feng Ni Chuan Fu Xiang Gao Yan Liu Pengxiang Xu Liu Liu Ye Lv Songsen Fu Ying Sun Daxiong Han Yan-Mei Li Yufen Zhao | 2015 | Science China Chemistry2015，58，3： | 3 |
| 14 | Numerical study of successive CMEs during November 4―5, 1998显示文摘We present the solar-terrestrial transit process of three successive coronal mass ejections (CMEs) of November 4―5, 1998 originating from active region 8375 by using a time-dependent three-dimensional magnetohydrodynamics (MHD) simula-tion. These CMEs interacted with each other while they were propagating in inter-planetary space and finally formed a 'complex ejecta'. A newly developed SIP-CESE MHD model was applied to solve MHD equations numerically. The quiet solar wind was started from Parker-like 1D solar wind solution and the magnetic field map was calculated from the solar photospheric magnetic field data. In our simulation, the ejections were initiated using pulse in the real active region 8375. The interplanetary disturbance parameters, such as speed, direction and angular size of the expanding CME, were determined from the SOHO/LASCO data with the cone-model. We discussed the three-dimensional aspects of the propagation, in-teraction and merging of the three ejections. The simulated interplanetary shocks were compared with the nearby-Earth measurement. The results showed that our simulation could reproduce and explain some of the general features observed by satellite for the 'complex ejecta'. | ZHOU YuFen & FENG XueShang SIGMA Weather Group, State Key Laboratory for Space Weather, Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100190, China | 2008 | Science China(Technological Sciences)2008，51，10： | 3 |
| 15 | The Characteristics of Gastrin Receptor Expression in Gastric Cancer显示文摘Objective: To investigate the characteristics and significance of gastrin receptor (GR) expression in gastric cancer. Methods: The content and affinity of GR were determined in 34 specimens of gastric cancer using radioligand binding assay. The correlation was analyzed between GR expression in tumors and tumor sites, stages, grades, DNA of gastric cancer cells, GR of adjacent normal gastric mucosa, survival time. Results: Among the 34 cases of gastric cancer, 16 patients (47.1%) had positive GR in specimens of gastric cancer, with high-affinity GR in 14 cases (41.2%) and low-affinity GR in 2 cases. Of high-affinity GR, 9 cases had cancers with GR>10 fmol/mg.protein (39.5±14.4 fmol/mg.protein), 5 cases with GR≤10fmol/mg.protein (6.0±2.8 fmol/mg.protein). High-affinity GR was easier to be expressed in cancers ofgastric body (7/9) and cardia (3/6) than in gastric antrum (4/19). The expression of GR in gastric cancer accorded well with that in normal gastric mucosa at the same sites, but with more high-special binding sites than the latter (39.5±14.4 vs 26.1±16.6 fmol/mg.protein). A significantly greater proportion of patients withⅢ+Ⅳ stages (13/24) had high-affinity GR compared with I+II stages (1/10) of gastric cancers. During a follow-up of 23-61 months, 11 of 13 cases with high-affinity GR were dead, whereas 4 of 11 cases with low-affinity or negative GR were dead in Ⅲ+Ⅳ stages of gastric cancer. Conclusion: GR is an important factor in the autocrine growth of gastric cancer cells, and helpful in the prediction of prognosis and guidance of treatment with GR antagonists. | HUANGGuangjian ZHANGYanling LEZhuqin YUFen ZHANGGuangming DENShouzhen NIQuanxing | 2003 | The Chinese-German Journal of Clinical Oncology2003，2，3： | 3 |
| 16 | Exploring the binding mechanism of thioflavin-T to the β-amyloid peptide by blind docking method显示文摘Using blind dock method,we find that thioflavin-T(ThT) can bind to both monomers and fibrils of the full-length β-amyloid peptide(Aβ1-42) and has a higher binding affinity to the fibrils.It is shown that the hydrophobic interaction between the ligand(ThT) and substrate(Aβ1-42) are stronger than hydrogen bonds.Furthermore,ThT tends to be located near the C-terminus of Aβ monomer through hydrophobic and electrostatic interactions,while it tends to contact the residues Met35 and Gly27 of the fibril surface mainly through hydrophobic interaction.Finally,according to the docking results and ThT fluorescence assay,a kinetic equation is proposed to deduce the aggregation rate coefficient of Aβ1-42. | ZHAO DeSheng CHEN YongXiang LIU Qian ZHAO YuFen LI YanMei | 2012 | Science China Chemistry2012，55，1： | 3 |
| 17 | Polymorphic Alu insertions and their associations with MHC class I alleles and haplotypes in Han and Jinuo populations in Yunnan Province,southwest of China显示文摘The associations of polymorphic Alu insertions (POALINs) with major histocompatibility complex (MHC) class I genes enable us to better identify origins and evolution of MHC class I region haplotypes in different populations. For further studying origins and evolution of MHC class I region haplotypes in Han and Jinuo populations in Yunnan Province, we investigated frequencies of five POALINs, their associations with HLA-A and -B, the three-loci POALINs haplotype frequencies and HLA/POALIN four-loci haplotype frequencies within the alpha block of MHC class I region. We found that a strong positive association between AluHG and HLA-A*02 is in Jinuo, but not in Yunnan Han. These results suggest that MHC class I region haplotypes of the two studied populations might derive from different progenitor haplotypes and MHC I-POALINs are informative genetic markers for investigating origins and evolution of MHC class I region haplotypes in different populations. | Yufeng Yao 1, Li Shi 1, Lei Shi, Keqin Lin, Yufen Tao, Liang Yu, Hao Sun, Xiaoqin Huang, Yanhan Li, Jiayou Chu Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, China | 2009 | Journal of Genetics and Genomics2009，36，1： | 2 |
| 18 | The influence of scope, depth, and orientation of external technology sources on the innovative performance of Chinese firms显示文摘 | Jin Chen Yufen Chen Wim Vanhaverbeke | 2011 | Technovation2011，，8： | 2 |
| 19 | Applications of nanogenerators for biomedical engineering and healthcare systems显示文摘The dream of human beings for long living has stimulated the rapid development of biomedical and healthcare equipment.However,conventional biomedical and healthcare devices have shortcomings such as short service life,large equipment size,and high potential safety hazards.Indeed,the power supply for conventional implantable device remains predominantly batteries.The emerging nanogenerators,which harvest micro/nanomechanical energy and thermal energy from human beings and convert into electrical energy,provide an ideal solution for self-powering of biomedical devices.The combination of nanogenerators and biomedicine has been accelerating the development of self-powered biomedical equipment.This article first introduces the operating principle of nanogenerators and then reviews the progress of nanogenerators in biomedical applications,including power supply,smart sensing,and effective treatment.Besides,the microbial disinfection and biodegradation performances of nanogenerators have been updated.Next,the protection devices have been discussed such as face mask with air filtering function together with real-time monitoring of human health from the respiration and heat emission.Besides,the nanogenerator devices have been categorized by the types of mechanical energy from human beings,such as the body movement,tissue and organ activities,energy from chemical reactions,and gravitational potential energy.Eventually,the challenges and future opportunities in the applications of nanogenerators are delivered in the conclusive remarks. | Wanli Wang Jinbo Pang Jie Su Fujiang Li Qiang Li Xiaoxiong Wang Jingang Wang Bergoi Ibarlucea Xiaoyan Liu Yufen Li Weijia Zhou Kai Wang Qingfang Han Lei Liu Ruohan Zang Mark HRümmeli Yang Li Hong Liu Han Hu Gianaurelio Cuniberti | 2022 | InfoMat2022，4，2： | 2 |
| 20 | Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine显示文摘Dear Editor,Urine passes through the entire kidney and urinary tract system starting from the glomerulus and ending to the urethra.Cells in the kidney and urinary tract could be exfoliated from the epithelium into the urine,while leukocyte could infiltrate from the local tissue into the urine,which makes the urine a useful subject for clinical evaluation of relevant diseases. | Yujia Wang Yu Zhao Zixian Zhao Dandan Li Hao Nie Yufen Sun Xiaobei Feng Ting Zhang Yu Ma Jing Nie Guangyan Cai Xiangmei Chen Wei Zuo | 2021 | Protein & Cell2021，12，4： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员