|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A Study of the Technique of Western Blot for Diagnosis of Lyme Disease caused by Borrelia afzelii in China显示文摘Objective To study the technique of Western blot for the diagnosis of Lyme disease caused by Borrelia afzelii in China and to establish the standard criteria by operational procedure. Methods FP1, which is the representative strain of B. afzelii in China, was analyzed by SDS‐PAGE, electro transfer and immunoblotting assays. The molecular weights of the protein bands of FP1 were analyzed by Gel‐Pro analysis software. In a study using 451 serum samples (159 patients with Lyme disease and 292 controls), all observed bands were recorded. The accuracy of the WB as a diagnostic test was established by using the ROC curve and Youden index. Results Criteria for a positive diagnosis of Lyme disease were established as at least one band of P83/100, P58, P39, OspB, OspA, P30, P28, OspC, P17, and P14 in the IgG test and at least one band of P83/100, P58, P39, OspA, P30, P28, OspC, P17, and P41 in the IgM test. For IgG criteria, the sensitivity, specificity and Youden index were 69.8%, 98.3%, and 0.681, respectively; for IgM criteria, the sensitivity, specificity and Youden index were 47%, 94.2%, and 0.412, respectively. Conclusion Establishment of WB criteria for B. afzelii is important in validating the diagnostic assays for Lyme disease in China. | LIU Zhi Yun HAO Qin HOU Xue Xia JIANG Yi GENG Zhen WU Yi Mou WAN Kang Lin | 2013 | Biomedical and Environmental Sciences2013，26，3： | 7 |
| 2 | Discovery of Metastasis-Associated Biomarkers in Ovarian Cancer Using SELDI-TOF: An in Vitro and Clinical Study显示文摘OBJECTIVE To identify metastasis-related biomarkers in humanovarian cancer cell lines and in serum.METHODS We isolated total protein from cell lysis solutionsand cultured supernatants from 2 human ovarian cancer cell linesand used SELDI-TOF-MS to detect the differential expressionof the proteins in the 2 cell lines.The proteomic spectra weregenerated using weak cation exchange chips.The biomarkerswere validated by analyzing serum proteins or peptides in ovariancancer patients,relapsed ovarian cancer patients,patients withbenign ovarian tumors,and healthy people.RESULTS Four proteins in the culture supernatant fromHO-8910PM cells were up-regulated,relative to the culturesupernatant of HO-8910 cells.One protein (3,144 Da m/z value)was up-regulated in both the cell lysis solution and in the culturesupernatant of HO-8910PM cells.In addition,expression of the3,144 Da m/z protein differed significantly between serum fromthe 26 ovarian cancer patients,from the 22 relapsed ovarianpatients and from the 37 healthy women (P<0.01).However,therewas no difference between patients with benign ovarian tumorsand healthy people (P>0.5).CONCLUSION Ovarian cancer cell lines with high or lowmetastatic potential have distinct protein profiles.Protein 3,144Da m/z could be a useful biomarker for diagnosing ovarian cancermetastasis. | Zhiguo Zheng Yun Gao Linhui Gu Hanzhou Mou Chihong Zhu Jianqing Zhu Shenhua Xu | 2009 | Clinical oncology and cancer resexreh2009，6，5： | 6 |
| 3 | CORONARY ANGIOGRAPHY WITH DUAL SOURCE COMPUTED TOMOGRAPHY:INITIAL EXPERIENCE显示文摘Objective To explore the scan technique and image quality of coronary angiography with dual source computed tomography(CT) without oral metoprolol preparation.Methods Plain and enhanced dual source CT coronary angiography without oral metoprolol preparation was prospectively performed in 600 patients.Calcium scoring with plain scan images as well as multi-planar reconstruction(MPR),maximum intensity projection(MIP),and volume rendering technique(VRT) reconstruction with enhanced scan images were performed in all cases.The scan technique and post-reconstruction experience was summarized.The image quality was classified as 1 to 4 points,and coronary segments classified according to the American Heart Association standards were evaluated.Results The average calcium score of the 600 cases was 213.6±298.7(0-3 216.5).The average heart rate of the enhanced scan was 82.1±16.2(47-139) bpm.The post-reconstruction methods with which coronary segments could be shown as best as possible consisted of single phase reconstruction method,two or more phases supplemented method,and electrocardiogram editing method.Altogether 8 457 coronary segments were evaluated,among which 97.2% were evaluated as point 1,1.7% point 2,0.5% point 3,and 0.6% point 4.The coronary segments in 261 cases were completely normal,while 360 segments were diagnosed with <50% stenosis and 625 segments with ≥50% stenosis.Conclusions Excellent coronary artery image can be obtained with dual source CT in patients with any heart rate without oral metoprolol preparation.Heart rate is not a major source of the artifact,coronary segments can be well shown with single or multiple-phase reconstruction method. | Zhu-hua Zhang Zheng-yu Jin Shu-yang Zhang Song-bai Lin Dong-jing Li Ling-yan Kong Yi-ning Wang Lan Song Yun Wang Wen-min Zhao Wen-bin Mou Li-ren Zhang Wen-ling Zhu Qi Miao Qi Fang | 2007 | Chinese Medical Sciences Journal2007，22，4： | 4 |
| 4 | Investigation of Self-Priming Process of a Centrifugal Pump with Double Blades显示文摘The gas-liquid two-phase flow patterns of a centrifugal pump during the self-priming process were investigated numerically and experimentally.The Euler-Euler multiphase model and SST k-ω turbulence model were applied for simulating the self-priming process.Meanwhile,the changes of motor speed and self-priming height were considered in the simulation.The overall transient two-phase flow features and water level distributions were mapped.Results showed that the self-priming process was divided into three stages.The liquid level in inlet-pipe rose in oscillation during self-priming process.The variations of water level during self-priming process of numerical simulation and test result agreed well.The inlet-pipe(Ver)was filled at 22 s and 24 s respectively numerically and experimentally.The bubble cloud circulated in the volute during middle stage of self-priming process,and breakup into smaller bubbles by shear force and tongue,and then discharged into chamber.The bubbles in the outlet-pipe mainly included bubbly flow and slug flow at the last stage of self-priming process,which is morphologically consistent with the test results.Also,during the self-priming process,the reflux liquid was pressed by blades and fully mixed with gas;that is the way to realizing the function of self-priming. | QIAN Heng MOU Jiegang REN Yun ZHU Zhibing LIU Nuojia ZHENG Shuihua WU Denghao | 2021 | Journal of Thermal Science2021，30，3： | 3 |
| 5 | Unsteady Flow and Structural Behaviors of Centrifugal Pump under Cavitation Conditions显示文摘Cavitation has a significant e ect on the flow fields and structural behaviors of a centrifugal pump. In this study, the unsteady flow and structural behaviors of a centrifugal pump are investigated numerically under di erent cavitation conditions. A strong two-way coupling fluid-structure interaction simulation is applied to obtain interior views of the e ects of cavitating bubbles on the flow and structural dynamics of a pump. The renormalization-group k-ε turbulence model and the Zwart–Gerbe–Belamri cavitation model are solved for the fluid side, while a transient structural dynamic analysis is employed for the structure side. The di erent cavitation states are mapped in the head-net positive suction head(H-NPSH) curves and flow field features inside the impeller are fully revealed. Results indicate that cavitating bubbles grow and expand rapidly with decreasing NPSH. In addition, the pressure fluctuations, both in the impeller and volute, are quantitatively analyzed and associated with the cavitation states. It is shown that influence of the cavitation on the flow field is critical, specifically in the super-cavitation state. The e ect of cavitation on the unsteady radial force and blade loads is also discussed. The results indicate that the averaged radial force increased from 8.5 N to 54.4 N in the transition progress from an onset cavitation state to a super-cavitation state. Furthermore, the structural behaviors, including blade deformation, stress, and natural frequencies, corresponding to the cavitation states are discussed. A large volume of cavitating bubbles weakens the fluid forces on the blade and decreases the natural frequencies of the rotor system. This study could enhance the understanding of the e ects of cavitation on pump flow and structural behaviors. | Denghao Wu Yun Ren Jiegang Mou Yunqing Gu Lanfang Jiang | 2019 | Chinese Journal of Mechanical Engineering2019，32，1： | 3 |
| 6 | High Initial Reversible Capacity and Long Life of Ternary SnO_(2)-Co-carbon Nanocomposite Anodes for Lithium-Ion Batteries显示文摘The two major limitations in the application of SnO_2 for lithium?ion battery(LIB) anodes are the large volume variations of SnO_2 during repeated lithiation/delithiation processes and a large irreversible capacity loss during the first cycle, which can lead to a rapid capacity fade and unsatisfactory initial Coulombic e ciency(ICE). To overcome these limitations, we developed composites of ultrafine SnO_2 nanoparticles and in situ formed Co(CoSn) nanocrystals embedded in an N?doped carbon matrix using a Co?based metal–organic framework(ZIF?67). The formed Co additives and structural advantages of the carbon?confined SnO_2/Co nanocomposite e ectively inhibited Sn coarsening in the lithiated SnO_2 and mitigated its structural degradation while facilitating fast electronic transport and facile ionic di usion. As a result, the electrodes demonstrated high ICE (82.2%), outstanding rate capability(~ 800 mAh g^(-1) at a high current density of 5 A g^(-1)), and long?term cycling stability(~ 760 mAh g^(-1) after 400 cycles at a current density of 0.5 A g^(-1)). This study will be helpful in developing high?performance Si(Sn)?based oxide, Sn/Sb?based sulfide, or selenide electrodes for LIBs. In addition, some metal organic frameworks similar to ZIF?67 can also be used as composite templates. | Pan Deng Jing Yang Shengyang Li Tian-E Fan Hong-Hui Wu Yun Mou Hui Huang Qiaobao Zhang Dong-Liang Peng Baihua Qu | 2019 | Nano-Micro Letters2019，11，1： | 2 |
| 7 | Unique sandwich design of high-efficiency heat-conducting phosphor-in-glass film for high-quality laser-driven white lighting显示文摘Multi-color phosphor-in-glass(PiG)film has been considered as a promising color converter in high-quality laser lighting owing to its outstanding merits of phosphor versatility,tunable luminescence,and simple preparation.However,the opto-thermal properties of PiG film are severely affected by the photon reabsorption and backward scattering of phosphor structure and the heat conduction of substrate.Herein,a unique sandwich design of phosphor structure was introduced in the multi-color PiG film for high-quality laser lighting.By elaborately synthesizing the borosilicate glass with low glass transition temperature(T_(g)),similar expansion coefficient,and high refractive index(RI),the sandwiched PiGs were prepared by sintering(~600℃)broadband green and red phosphor glass films on the double sides of sapphire.The green and red PiG films were tightly coated on the sapphire with no delamination and maintained higher luminescence intensity than raw phosphors at high temperatures.By simultaneously coupling photon reabsorption and backward scattering,the sandwiched green PiG film-sapphire-red PiG film(G-S-R PiG)yields a high-quality white light with a high luminous efficacy of 163 lm/W and an excellent color rendering index(CRI)of 85.4 under a laser power of 2.4 W,which are the best comprehensive results yet reported.Benefiting from the ingenious sandwich design with heat-conducting sapphire and thin PiG films,the G-S-R PiG displays low working temperatures(<200℃)under high-power laser excitation.This work reveals the role of sandwiched phosphor structure in photon loss and heat dissipation,which provides a new strategy to design PiG films for high-quality laser lighting. | Yang PENG Zikang YU Jiuzhou ZHAO Qing WANG Jiaxin LIU Bo SUN Yun MOU Mingxiang CHEN | 2022 | Journal of Advanced Ceramics2022，11，12： | 2 |
| 8 | Spectrometric study of α-methylene aromatic araminenone and aminoketone显示文摘Thirteenα-methylene aromatic araminenone and fourα-methylene aromatic aminoketones were prepared by modified Mannich reaction.On the basis of isotopic labeling,a plausible way of cleavage was proposed for the formation of the M^+-17 fragment peak in the MS of theα-methylene aromatic araminenone and aminoketones.The characteristic chemical shift of the olefinic protons in ~1H NMR is also discussed. | Li Yuan Mou Zi Yun Lin Li Ya Zhu Xiao Tian Liang | 2007 | Chinese Chemical Letters2007，18，10： | 1 |
| 9 | USING OF MULTISLICE HELICAL CT COLONOGRAPHY IN PATIENTS WITH MALIGNANT LESIONS OF COLON显示文摘Objective To investigate the techniques and clinical applications of multislice helical computed tomography (CT) colono- graphy in colonic lesions. Methods Fifty-nine patients with malignant lesions of colon underwent volume scanning using multislice helical CT. Four types of reconstruction including CT virtual colonoscopy (CTVC), shaded surface display (SSD), Raysum, and mu- ltiple planar reconstruction (MPR) were used for image post-processing. The results were compared with those of colonos- copy and pathology. Results Multislice helical CT colonography detected 54 colorectal carcinomas, 4 adenomas with focal carcinoma, 1 non-Hodgkin’s lymphoma (NHL). The lesions’ number, size, location, morphology, stricture of intestinal cavity, infiltration, and metastasis were shown satisfactorily by multislice helical CT colonography. Whole colon could be shown in all patients. CT colonography displayed 4 synchronous colonic tumors, 1 ascending colon carcinoma combined with left renal carcinoma among 54 patients with colonic carcinomas. The accuracy of location of CT colonography was 100%. There were 9 cases that CT showed the tumor location was different from the finding of conventional colonoscopy, while all of the CT location were proven exact by operation. CT colonography also displayed the infiltration of serous layer and fatty tissue in 45 cases; 21 cases matched the pathological results in all the 24 cases of suspicious lymph node metastasis, the sensitivity was 87.5%, the specificity was 90.6%; 9 cases hepatic metastasis, 2 ovarian metastasis, and 1 double adrenal gland metastasis. Conclusions Multislice helical CT colonography is effective in preoperative diagnosis, location, stage, and making treatment plan of colorectal carcinoma. It can display the portion not seen during colonoscopy and may have an adjunctive role. | Ming-wei Qin Wei-dong Pan Guan-ning Cong Yun Wang Yun-qing Zhang Wen-bin Mou Zheng-yu Jin | 2005 | Chinese Medical Sciences Journal2005，20，3： | 1 |
| 10 | On generalized clrculants over a Boolean algebra显示文摘 | Chao Chong - yun Zhang Mou -chen | 1984 | Linear Algebra and Its Applications1984，62，： | 1 |
| 11 | Spectrometric Study of α-Phenylcinnamic Acids显示文摘Fourteen substituted α-phenylcinnamic acids were prepared by the classical Perkin condensation. A plausible way of cleavage was involved in the formation of the specific fragment peaks in the MS of the α-phenylcinnamic acids . The characteristic chemical shift of the olefinic proton in HNMR is also | Xin HE Li Yuan MOU Zi Yun LIN Li Ya ZHU Xiao Tian LIANG (Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College . Beijing 100050 ) | 1997 | Chinese Chemical Letters1997，8，10： | 0 |
| 12 | 1959-2021年间热带雨林区域的蒸发皿蒸发量呈下降趋势显示文摘1959-2021年间热带雨林区域的蒸发皿蒸发量呈下降趋势蒸发皿蒸发量(E_(pan))是衡量大气蒸发需求的重要指标。基于物理模型对西双版纳热带植物园中热带雨林综合气象观测场(XTBG气象站)的气象资料进行分析,有助于提高我们对西双版纳热带雨林区域水文循环状况的认识。本文利用1959-2021年的观测资料,研究了E_(pan)的长期变化趋势,并进行了趋势检验、周期性评价和突变分析等相关分析。基于1979-2008年D20 E_(pan)数据和相关气象资料,利用Penman-Monteith和PenPan模型对E_(pan)进行模拟,采用偏微分归因法分析了影响E_(pan)的主导因素。研究结果表明,E_(pan)具有明显的周期变化,19 a为第一主周期。而且,西双版纳地区存在明显的‘蒸发悖论’现象。E_(pan)在1959-2008年和2009-2018年均呈下降趋势,其中1959-2008年下降幅度达到显著水平,为-3.404 mm·a^(-2)。通过对比分析,认为PenPan模型更适合用于模拟西双版纳地区的E_(pan)。为了确定影响E_(pan)的主要气象因子,选取了D20蒸发皿完整监测时期的数据(1979-2008)进行归因计算。太阳净辐射和饱和蒸汽压差的减小趋势可以有效抵消气温上升对E_(pan)的促进作用。因此,净辐射和饱和蒸汽压差的变化是西双版纳‘蒸发悖论’现象的主要触发因素。 | Yan Jin Ying Zhang Xin Yang Mou Zhang Xin-Bo Guo Yun Deng Yue-Hua Hu Hua-Zheng Lu Zheng-Hong Tan | 2024 | Journal of Plant Ecology2024，17，1： | 0 |
| 13 | 共担与赋能:有温度的社区与住房显示文摘Introduction On Apr.15-16,2023,the 2022 Annual Conference of the Housing and Community Planning Committee of the Urban Planning Society of China(UPSC)was successfully held at the Chongqing Planning Exhibition Gallery,Chongqing.The conference was hosted by the Housing and Community Planning Committee of the UPSC. | 尹稚 王宇 江维 Yu Ying Liu Jiayan Yao Nan Wang Chenghui Fang Xiaotao Wang Ying Xi Wenqin Pan Chenyue Mou Yanchuan Wei Wei Li Yun Xiao Xiao Chen Yulin Zhao Di Liu Wei Zhang Jiuhe Deng Yi | 2023 | China City Planning Review2023，32，4： | 0 |
| 14 | Laser spot associated high-saturation phosphor-in-glass film for transmissive and reflective high-brightness laser lighting显示文摘Phosphor-in-glass(PiG)film is a promising luminescent material in high-brightness laser lighting for its advantages of high efficiency,outstanding color quality,and low-cost preparation,which must bear high laser power(LP)and laser power density(LPD)simultaneously to enable high-luminance light.Herein,laser spot associated high-saturation PiG film was proposed for transmissive and reflective high-brightness laser lighting.Two types of PiG films were prepared by printing and sintering La_(3)Si_(6)N_(11):Ce^(3+)(LSN)phosphor-borosilicate glass pastes on a sapphire substrate(PiG-S)and an AlN substrate(PiG-A),respectively.The PiG films with perfect crystal structure of phosphor were reliably bonded on the substrates.The effects of laser spot areas on the luminescence saturation of LP and LPD were investigated in the PiG films.With the increase of laser spot area from 0.5 to 2.5 mm^(2),the LP threshold of PiG films is gradually raised,while the LPD threshold of PiG films is decreased.The PiG-S withstands a high LP of 23.46 W and a high LPD of 20.64 W/mm^(2),enabling white light with a luminous flux of 3677 lm.The PiG-A withstands a high LP of 41.12 W and a high LPD of 35.56 W/mm^(2),enabling white light with a luminous flux of 2882 lm.Moreover,the PiG-A maintains lower working temperature compared with the PiG-S,and the temperatures reduce with the increasing laser spot area.The results demonstrate that the laser spot associated PiG films realize high saturation thresholds of LP and LPD simultaneously,and enable high luminance for laser lighting. | Zikang Yu Jiuzhou Zhao Qing Wang Yun Mou Mingxiang Chen Yang Peng | 2023 | Journal of Advanced Ceramics2023，12，9： | 0 |
| 15 | A Numerical Investigation on the Characteristics of the Radial Force in a Cycloid Gerotor Pump显示文摘In order to improve the performances of a cycloid gerotor pump,the variations of the radial force induced by different rotating speeds and outlet pressures are analyzed numerically.Using the numerical simulations as a basis,an improved oil inlet and outlet groove structure is proposed.The results show that the radial force decreases with the decrease of the outlet pressure and of the rotor speed.Compared with the original model,the large-end oil inlet line and pressure line of the new oil groove are claw-shaped.This configuration can effectively weaken the pressure changes inside the gerotor pump and reduce accordingly the radial force on the inner rotor. | Lingzhi Yu Yunqing Gu Jiegang Mou Denghao Wu Zhenfu Chen Yun Ren | 2020 | Fluid Dynamics & Materials Processing2020，16，5： | 0 |
| 16 | LES Analysis of the Unsteady Flow Characteristics of a Centrifugal Pump Impeller显示文摘Stall phenomena increase the complexity of the internal flow in centrifugal pump impellers.In order to tackle this problem,in the present work,a large eddy simulation(LES)approach is applied to determine the characteristics of these unstable flows.Moreover,a vorticity identification method is used to characterize quantitatively the vortex position inside the impeller and its influencing area.By comparing the outcomes of the numerical simulations and experimental results provided by a Particle Image Velocimetry(PIV)technique,it is shown that an apparent“alternating stall”phenomenon exists inside the impeller when relatively small flow rate conditions are considered.The stall is generated near the suction side of the blade inlet,grows towards the high-pressure side of the blade in the circumferential direction,and gradually attenuates.As the flow rate decreases,the number of stalls remains unchanged,while the related influencing area and strength gradually increase and the circumferential velocity increases. | Ting Zhang Denghao Wu Shijun Qiu Peijian Zhou Yun Ren Jiegang Mou | 2022 | Fluid Dynamics & Materials Processing2022，18，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员