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| 1 | Mesenteric lymph reperfusion may exacerbate brain injury in a rat model of superior mesenteric artery occlusion shock显示文摘BACKGROUND:The intestinal lymphatic pathway and intestinal ischemia/reperfusion are mainly involved in mesenteric lymph duct ligation or drainage;moreover,intervention by reducing the lymph liquid reflux might relieve lung and other organ dysfunction induced by intestinal ischemia/reperfusion;however,research addressing mesenteric lymph reperfusion (MLR) and brain injury has not yet to be reported.OBJECTIVE:To observe the effect of MLR on brain tissue in a rat model of superior mesenteric artery occlusion (SMAO) shock,and to explore the molecular mechanism of MLR.DESIGN,TIME AND SETTING:A randomized,controlled,animal experiment at a neuro-pathophysiology level was performed at the Institute of Microcirculation,Hebei North University;Department of Pathophysiology,Basic Medical College;Department of Pathology,the First Hospital of Hebei North University between December 2007 and March 2009.MATERIALS:Adenosine triphosphate (ATP) standard was provided by the National Institute for the Control of Pharmaceutical and Biological Products;lactic acid (LA),superoxide dismutase (SOD),malonaldehyde (MDA),nitrogen monoxidum (NO),nitric oxide synthase (NOS),myeloperoxidase (MPO) and ATPase assay kits were provided by Nanjing Jiancheng Bioengineering Institute,China.METHODS:A total of 24 male Wistar rats were randomly divided into four groups.In the sham-surgery group (n=6),both the mesenteric lymph duct and the superior mesenteric artery were not blocked;in the MLR group (n=6),the mesenteric lymph duct was occluded for 1 hour followed by 2-hour reperfusion;in the SMAO group (n=6),the superior mesenteric artery was occluded for 1 hour followed by 2-hour reperfusion;in the MLR + SMAO group (n=6),both the mesenteric lymph duct and superior mesenteric artery were occluded for 1 hour followed by 2-hour reperfusion.MAIN OUTCOME MEASURES:Mean arterial blood pressure prior to and following ischemia/reperfusion;brain tissue morphology levels of LA,MDA,SOD,NO,NOS,MPO,ATPase and ATP following reperfusion.RESULTS:MLR did not cause changes in mean arterial blood pressure,brain tissue morphology,LA,MDA,NO,ATP,SOD,NOS,MPO and ATPase.However,SMAO caused a rapid decrease and gradual increase of mean arterial blood pressure.Neuronal necrosis,degeneration and swelling were observed in brain tissue.Contents of MDA,NO,LA and ATP as well as activities of NOS and MPO were significantly increased (P < 0.05),but activities of SOD and Na+-K+-ATPase were significantly decreased (P < 0.05).MLR aggravated neuronal damage in a rat model of SMAO shock.Following MLR,mean arterial blood pressure was significantly decreased (P < 0.05),contents of MDA and NO as well as activities of NOS and MPO were significantly increased (P < 0.05),but activities of Ca2+-ATPase,Mg2+-ATPase and Ca2+-Mg2+-ATPase as well as ATP content were significantly decreased (P < 0.05).CONCLUSION:MLR aggravates brain injury in a rat model of SMAO shock,which correlates with oxygen-derived free radical injury,NO synthesis and release,sequestration of neutrophilic granulocytes,decreasing activity of cell membrane pumps and energy metabolism dysfunction.Pathogenesis of the intestinal lymphatic pathway should be thoroughly investigated to prevent ischemia/reperfusion injury. | Zigang Zhao Chunyu Niu Aimin Shang Jiaming Tian Rui Han Chunhui Zhang Yuping Zhang Jing Zhang | 2010 | Neural Regeneration Research2010，5，9： | 7 |
| 2 | Impacts of Four Types of ENSO Events on Tropical Cyclones Making Landfall over China's Mainland Based on Three Best-track Datasets显示文摘Impacts of El Nin o Modoki(ENM), La Nin a Modoki(LNM), canonical El Nin o(CEN) and canonical La Nin a(CLN) on tropical cyclones(TCs) that made landfall over China's Mainland during 1951–2011 are analysed using best-track data from China, the USA and Japan. Relative to cold phase years(LNM and CLN), landfalling TCs in warm years(ENM and CEN) have a farther east genesis location, as well as longer track lengths and durations, both in total and before landfall. ENM demonstrates the highest landfall frequency, most northerly mean landfall position, and shortest after-landfall sustainability(track length and duration), which indicate a more frequent and extensive coverage of China's Mainland by TCs, but with shorter after-landfall influence. CEN has low landfall frequency and the most southerly mean landfall location. LNM has the most westerly genesis location, being significantly farther west than the 1951–2011 average and leading to short mean track lengths and durations both in total or before landfall, all of which are significantly shorter than the 1951–2011 average. Variations in the low-level wind anomaly, vertical wind shear, mid-level relative humidity, steering flow, the monsoon trough and the western Pacific subtropical high(WPSH) can to some extent account for the features of frequency, location, track length and duration of landfalling TCs. Since ENSO Modoki is expected to become more frequent in the near future, the results for ENSO Modoki presented in this paper are of particular significance. | ZHANG Han GUAN Yuping | 2014 | Advances in Atmospheric Sciences2014，31，1： | 6 |
| 3 | Estimating soil ammonium adsorption using pedotransfer functions in an irrigation district of the North China Plain显示文摘Extensive use of chemical fertilizers in agriculture can induce high concentration of ammonium nitrogen(NH4^(+)_(-)N) in soil. Desorption and leaching of NH4^(+)_(-)N has led to pollution of natural waters. The adsorption of NH4^(+)_(-)N in soil plays an important role in the fate of the NH4^(+)_(-)N. Understanding the adsorption characteristics of NH4^(+)_(-)N is necessary to ascertain and predict its fate in the soil-water environment, and pedotransfer functions(PTFs) could be a convenient method for quantification of the adsorption parameters. Ammonium nitrogen adsorption capacity, isotherms, and their influencing factors were investigated for various soils in an irrigation district of the North China Plain. Fourteen agricultural soils with three types of texture(silt, silty loam, and sandy loam) were collected from topsoil to perform batch experiments. Silt and silty loam soils had higher NH4^(+)_(-)N adsorption capacity than sandy loam soils.Clay and silt contents significantly affected the adsorption capacity of NH4^(+)_(-)N in the different soils. The adsorption isotherms of NH4^(+)_(-)N in the 14 soils fit well using the Freundlich, Langmuir, and Temkin models. The models’ adsorption parameters were significantly related to soil properties including clay,silt, and organic carbon contents and Fe^(2+) and Fe^(3+) ion concentrations in the groundwater. The PTFs that relate soil and groundwater properties to soil NH4^(+)_(-)N adsorption isotherms were derived using multiple regressions where the coefficients were predicted using the Bayesian method. The PTFs of the three adsorption isotherm models were successfully verified and could be useful tools to help predict NH4^(+)_(-)N adsorption at a regional scale in irrigation districts. | Chunying WANG Defeng WU Xiaomin MAO Jingming HOU Lei WANG Yuping HAN | 2021 | Pedosphere2021，31，1： | 4 |
| 4 | Quantum dots protect against MPP+-induced neurotoxicity in a cell model of Parkinson's disease through autophagy induction显示文摘Autophagy is a basic cellular process that decomposes damaged organelles and aberrant proteins. Dysregulation of autophagy is implicated in pathogenesis of neurodegenerative disorders, including Parkinson's disease(PD). Pharmacological compounds that stimulate autophagy can provide neuroprotection in models of PD. Nanoparticles have emerged as regulators of autophagy and have been tested in adjuvant therapy for diseases. In this present study, we explore the effects of quantum dots(QDs) that can induce autophagy in a cellular model of Parkinson's disease. Cd Te/Cd S/Zn S QDs protect differentiated rat pheochromocytoma PC12 cells from MPP+-induced cell damage, including reduced viability, apoptosis and accumulation of α-Synuclein, a characteristic protein of PD. The protective function of QDs is autophagy-dependent. In addition, we investigate the interaction between quantum dots and autophagic pathways and identify beclin1 as an essential factor for QDs-induced autophagy. Our results reveal new promise of QDs in the theranostic of neurodegenerative diseases. | Lu Wang Xiaoming Li Yuping Han Ting Wang Yun Zhao Aldalbahi Ali Nahed Nasser El-Sayed Jiye Shi Wenfeng Wang Chunhai Fan Nan Chen | 2016 | Science China Chemistry2016，59，11： | 3 |
| 5 | Frequency steering of spaceborne clocks based on XPNAV-1 observations显示文摘Due to high stable rotations, timing of pulsars provides a natural tool to correct the frequency deviation of spaceborne atomic clocks. Based on processing the observational data about a year of Crab pulsar given by XPNAV-1 satellite, we study the possibility of correcting the frequency deviation of spaceborne atomic clocks using pulsar timing. According to the observational data in X-ray band and the timing model parameters from radio observations, the pre-fit timing residuals with a level of 67.66 μs are obtained. By fitting the slope of the timing residuals affected by the faked frequency-biased reference clock, we estimated successfully the relative frequency deviation of the reference clock. For a satellite clock with frequency deviation of the order about 10^(-12), a calibration accuracy with relative error of about 2% can be obtained from the Crab pulsar’s data for one year.The stability of the time scale based on Crab pulsar is about 10^(-12) for an interval of one year. | Mengna HAN Minglei TONG Liansheng LI Yongqiang SHI Tinggao YANG Yuping GAO | 2023 | Chinese Journal of Aeronautics2023，36，6： | 3 |
| 6 | Study on the Improvement of the Application of Complete Ensemble Empirical Mode Decomposition with Adaptive Noise in Hydrology Based on RBFNN Data Extension Technology显示文摘The complex nonlinear and non-stationary features exhibited in hydrologic sequences make hydrological analysis and forecasting difficult.Currently,some hydrologists employ the complete ensemble empirical mode decomposition with adaptive noise(CEEMDAN)method,a new time-frequency analysis method based on the empirical mode decomposition(EMD)algorithm,to decompose non-stationary raw data in order to obtain relatively stationary components for further study.However,the endpoint effect in CEEMDAN is often neglected,which can lead to decomposition errors that reduce the accuracy of the research results.In this study,we processed an original runoff sequence using the radial basis function neural network(RBFNN)technique to obtain the extension sequence before utilizing CEEMDAN decomposition.Then,we compared the decomposition results of the original sequence,RBFNN extension sequence,and standard sequence to investigate the influence of the endpoint effect and RBFNN extension on the CEEMDAN method.The results indicated that the RBFNN extension technique effectively reduced the error of medium and low frequency components caused by the endpoint effect.At both ends of the components,the extension sequence more accurately reflected the true fluctuation characteristics and variation trends.These advances are of great significance to the subsequent study of hydrology.Therefore,the CEEMDAN method,combined with an appropriate extension of the original runoff series,can more precisely determine multi-time scale characteristics,and provide a credible basis for the analysis of hydrologic time series and hydrological forecasting. | Jinping Zhang Youlai Jin Bin Sun Yuping Han Yang Hong | 2021 | Computer Modeling in Engineering & Sciences2021，，2： | 3 |
| 7 | Study on Colloidal Gold Immunochromatography Assay for Rapid Detection of Spectinomycin显示文摘[Objectives] This study was conducted to establish a rapid detection method for spectinomycin in pork,chicken,fish,shrimp flesh and water.[Methods]A test strip for rapid detection of spectinomycin in milk was developed by colloidal gold immunochromatography assay. [Results]The test strip had a detection limit of 50 μg/kg to milk with a detection time of 15 min,and the false positive rate and false negative rate were both 0. [Conclusions]The method is accurate,simple,reliable and convenient,and is suitable for rapid on-site spectinomycin detection. | Zhaoqin WANG Yuping WAN Xiaosheng WU Yu ZHANG Fangfang JIA Guangyao HAN Zhengxue PENG Fangyang HE | 2019 | Agricultural Biotechnology2019，8，1： | 3 |
| 8 | Preparation of P(St-NMA)microsphere inks and their application in photonic crystal patterns with brilliant structural colors显示文摘Patterned photonic crystals with structural colors on textile substrates have attracted a special attention due to the great advantages in application,which currently become a research hot-spot.This study utilized an ink-jet printing technology to prepare high-quality photonic crystal patterns with structural colors on polyester substrates.The self-assembly temperature of poly(styrene-N-methylol acrylamide)(P(St-NMA))microspheres set to construct photonic crystals were deeply optimized.Moreover,the structural colors of prepared photonic crystal patterns were characterized and evaluated.When the mass fraction of P(St-NMA)microspheres was 1.0 wt.%,the pH value ranged from 5 to 7,and the surface tension was in the range of 63.79 to 71.20 mN/m,inks could present the best print performance.At 60°C,prepared P(St-NMA)microsphere inks were good for printing to obtain patterned photonic crystals with regular arrangement and beautiful structural colors.Specifically,photonic crystals with different colors could be constructed by regulating the diameter of microspheres in inks,and prepared structural colors exhibited distinct iridescent phenomenon.The present results could provide a theoretical basis for the industrial realization of patterned photonic crystals by ink-jet printing technology. | Guojin Liu Pengshuai Han Liqin Chai Peng Lu Yuping He Lan Zhou | 2020 | Frontiers of Materials Science2020，14，1： | 3 |
| 9 | Processing for Zero-Failure Data of the Products显示文摘In this paper, an estimation method for reliability parameter in the case of zero-failuare data-synthetic estimation method is given. For zero-failure data of double-parameter exponential distribution, a hierarchical Bayesian estimation of the failure probability is presented. After failure information is introduced, hierarchical Bayesian estimation and synthetic estimation of the failure probability, as well as synthetic estimation of reliability are given. Calculation and analysis are performed regarding practical problems in case that life distribution of an engine obeys double-parameter exponential distribution. | Han Ming 1,2 & Cui Yuping 3 (1. Department of Statistics, Renmin University of China, Beijing 100872, P.R. China 2. Department of Mathematics, Zhejiang Ocean University, Zhoushan 316004, P.R. China 3. Department of Machine and Electron, Dongbei Power College, Jilin 130012, P.R. China) | 2002 | Journal of Systems Engineering and Electronics2002，13，3： | 3 |
| 10 | PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China显示文摘We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based observations.From 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,respectively.However,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased slightly.Those changes contributed to an overall SIAs increase in 2019.Higher molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted days.Mean molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban regions.Moreover,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich conditions.Our findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution. | Yangyang Zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng Yuping Zhang Jian Han Lijuan Zhang Jeffrey L.Collett Jr Xuejun Liu | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 11 | Effects of Substrate Temperature on the Properties of Mo-doped ZnO Films Prepared by RF Magnetron Sputtering显示文摘Transparent conducting molybdenum-doped zinc oxide (MZO) films were successfully prepared by radio frequency (RF) magnetron sputtering method on glass substrates under different substrate temperatures. The nature of MZO film is polycrystalline with hexagonal structure and a preferred orientation along c-axis. With increasing substrate temperature from room temperature to 400°C, the crystallinity of the films is deteriorated and the resistivity increases sharply due to both the decrease of carrier concentration and Hall mobility. The lowest resistivity achieved is 9.2×10-4Ω· cm with a high Hall mobility of 30 cm2·V-1·s-1 for the film deposited at room temperature. The average transmittance in the visible range exceeds 85% for all the samples. The optical band gap decreases from 3.30 to 3.25 eV with substrate temperature from room temperature to 400°C. | Xianwu Xiu Yuping Cao Zhiyong Pang Shenghao Han | 2009 | Journal of Materials Science & Technology2009，25，6： | 2 |
| 12 | Influence of mesenteric lymph reperfusion on neurotransmitter expression in brain tissue of a superior mesenteric artery occlusion shock rat model显示文摘BACKGROUND: Previous studies have shown that mesenteric lymph reperfusion (MLR) exacerbates brain injury in a rat model of superior mesenteric artery occlusion (SMAO) shock. However, little is known about the influence of MLR on neurotransmitter expression in brain tissue. OBJECTIVE: To observe the effect of MLR on brain tissue injury by measuring monoamine and cholinergic neurotransmitter levels. DESIGN, TIME AND SETTING: A randomized, controlled, animal experiment was performed at the Institute of Microcirculation, Hebei North University, China; Research Room of Microcirculation and Laboratory of Biochemistry, Department of Pathophysiology, Basic Medical College, Hebei North University between December 2007 and March 2009. MATERIALS: Choline acetyltransferase (ChAT) and acetylcholine esterase (AChE) kits were provided by Nanjing Jiancheng Bioengineering Institute, China; dopamine (DA) and noradrenalin (NE) standards were provided by the National Institute for the Control of Pharmaceutical and Biological Products; HP1100 chromatograph of liquid was provided by Agilent, USA. METHODS: A total of 24 male, Wistar rats were randomly assigned to 4 groups: sham-surgery, MLR, SMAO, and MLR + SMAO groups, with 6 rats in each group. In the MLR or SMAO groups, the mesenteric lymph duct or superior mesenteric artery was blocked for 1 hour. In the MLR + SMAO group, the mesenteric lymph duct and superior mesenteric artery were occluded for 1 hour, followed by 2-hour reperfusion. ChAT and AChE levels were measured using the synthesized and hydrolyzed acetylcholine method, respectively. Liquid chromatography was employed to quantitatively analyze DA and NE levels, using relative retention time and the external standard method. MAIN OUTCOME MEASURES: ChAT, AChE, DA, and NE levels. RESULTS: AChE levels were significantly increased, but ChAT levels were significantly decreased in the MLR and MLR + SMAO groups following 2-hour reperfusion (P < 0.01). However, AChE activity in the MLR + SMAO group was greater than in the MLR group (P < 0.05). DA and NE levels were significantly decreased in the SMAO and MLR + SMAO groups (P < 0.01), while DA levels in the MLR + SMAO group were less than in the SMAO group (P < 0.05). CONCLUSION: MLR exacerbated brain injury in a rat model of SMAO shock, which correlated with the intestinal lymphatic pathway. MLR decreased DA levels, but increased AChE activity, in a rat model of SMAO shock. | Chunyu Niu Zigang Zhao Aimin Shang Jiaming Tian Chunhui Zhang Rui Han Yuping Zhang Jing Zhang | 2010 | Neural Regeneration Research2010，5，11： | 2 |
| 13 | In vitro selection and identification of sweetpotato (Ipomoea batatas (L.) Lam.) plants tolerant to NaCl显示文摘 | Shaozhen He Yuanfeng Han Yuping Wang Hong Zhai Qingchang Liu | 2009 | Plant Cell Tissue and Organ Culture2009，，1： | 1 |
| 14 | Sequential pattern mining with gap constraints for discovery of the software bug features显示文摘 | Zeng Qiang Chen Yuping Han Gaowei | 2014 | Journal of Computational Information Systems2014，10，2： | 1 |
| 15 | Global lunar landing scheme and analyzes of objective and feasibility of manned landing in brief显示文摘 | HAN HONGSHUO JIANG YUPING | 2008 | Aerospace China2008，，9： | 1 |
| 16 | A new encoding based genetic algorithm for the traveling saleman problem显示文摘 | Wang Yuping Han Lixia LI Yinghua | 2006 | Engi- neering Optimization2006，38，1： | 1 |
| 17 | Design and synthesis of oxymatrine analogues overcoming drug resistance in hepatitis B virus through targeting host heat stress cognate 70显示文摘 | Gao Limei Han Yanxing Wang Yuping | 2011 | J Med Chem2011，54，3： | 1 |
| 18 | Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease显示文摘 | Cynthia A. Moylan Herbert Pang Andrew Dellinger Ayako Suzuki Melanie E. Garrett Cynthia D. Guy Susan K. Murphy Allison E. Ashley‐Koch Steve S. Choi Gregory A. Michelotti Daniel D. Hampton Yuping Chen Hans L. Tillmann Michael A. Hauser Manal F. Abdelmalek | 2014 | Hepatology2014，，2： | 1 |
| 19 | Effect of MA- Na copolymer adsorption on the colloidal stability of nanosized ZnO suspension 显示文摘 | Liufu Shengcong Xiao Hanning Li Yuping | 2005 | Materials Letter2005，59，： | 1 |
| 20 | Impact of alkyl meth acrylate maleic anhydride copolymers as pour point depress- ant on crystallization behavior of diesel fuel 显示文摘 | Han Sheng Song Yuping Ren Tianhui | 2009 | Energy & Fads2009，23，5： | 1 |
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