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| 1 | BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair显示文摘Calvarial bones are connected by fibrous sutures. These sutures provide a niche environment that includes mesenchymal stem cells(MSCs), osteoblasts, and osteoclasts, which help maintain calvarial bone homeostasis and repair. Abnormal function of osteogenic cells or diminished MSCs within the cranial suture can lead to skull defects, such as craniosynostosis. Despite the important function of each of these cell types within the cranial suture, we have limited knowledge about the role that crosstalk between them may play in regulating calvarial bone homeostasis and injury repair. Here we show that suture MSCs give rise to osteoprogenitors that show active bone morphogenetic protein(BMP) signalling and depend on BMP-mediated Indian hedgehog(IHH) signalling to balance osteogenesis and osteoclastogenesis activity. IHH signalling and receptor activator of nuclear factor kappa-Β ligand(RANKL) may function synergistically to promote the differentiation and resorption activity of osteoclasts. Loss of Bmpr1a in MSCs leads to downregulation of hedgehog(Hh) signalling and diminished cranial sutures. Significantly, activation of Hh signalling partially restores suture morphology in Bmpr1a mutant mice, suggesting the functional importance of BMP-mediated Hh signalling in regulating suture tissue homeostasis. Furthermore, there is an increased number of CD200+ cells in Bmpr1a mutant mice, which may also contribute to the inhibited osteoclast activity in the sutures of mutant mice. Finally, suture MSCs require BMPmediated Hh signalling during the repair of calvarial bone defects after injury. Collectively, our studies reveal the molecular and cellular mechanisms governing cell–cell interactions within the cranial suture that regulate calvarial bone homeostasis and repair. | Yuxing Guo Yuan Yuan Ling Wu Thach-Vu Ho Junjun Jing Hideki Sugii Jingyuan Li Xia Han Jifan Feng Chuanbin Guo Yang Chai | 2018 | Bone Research2018，6，4： | 12 |
| 2 | Analysis of the microbiota of sputum samples from patients with lower respiratory tract infections显示文摘唾沫是从患更低的呼吸的道感染的病人收集的最普通的样品,它为这些感染的细菌的鉴定是关键的。在这研究,我们与更低的呼吸的道感染从 101 个病人注册了 101 件唾沫样品。开始,在唾沫包含的细菌的 16S rDNA V3 hypervariable 区域的 pyrosequencing 为 microbiota 分析作为一条文化无关的途径被利用。为比较,用一个文化依赖者的临床的实验室测试为样品也被做的唾沫的一样的队自动化了细菌的鉴定系统。由 pyrosequencing, > 70,000 DNA 碎片在被 Ribosomal 数据库工程(RDP ) 过程分析以后被发现并且分类进 129 个细菌的类。大多数序列属于几个占优势的类,例如链球菌和葡萄球菌,显示这些类起在更低的呼吸的道感染的一个重要作用。另外,属于潜在的原因的代理人的一些序列例如霉浆菌, Haemophilus,和 Moraxella,也被发现,但是这些序列没被临床的实验室测试发现。为两个方法检测的九个类,方法的敏感被比较,结果证明 pyrosequencing 是更敏感的,除了 Klebsiella 和 Mycobacterium。显著地,这个方法揭示了更复杂的细菌的社区,它为细菌的察觉显示出一个有希望的能力。 | Yuhua Zhou Ping Lin Qingtian Li Lizhong Han Huajun Zheng Yanxia Wei Zelin Cui Yuxing Ni Xiaokui Guo | 2010 | Acta Biochimica et Biophysica Sinica2010，42，10： | 8 |
| 3 | Achieving high throughput and TCP Reno fairness in delay-based TCP over large networks显示文摘运输控制协议(TCP ) 广泛地在象 FTP,电子邮件和 http 那样的相连、无线的因特网应用程序被使用了。众多的拥挤回避算法被建议了在各种各样的情形改进 TCP 的表演,特别为高速度和无线网络。尽管不同算法可以在不同网络条件下面完成不同性能改进,设计能越过大量网络条件表现很好的一个拥挤算法仍然是大挑战。基于延期的 TCP 有一个潜力在挑战上面克服。然而,有 TCP Reno 的基于延期的 TCP 的不公平问题广泛地在宽区域网络上堵住基于延期的 TCP 的推广。在这份报纸,我们建议了一个新奇基于延期的拥挤控制算法,命名快适合,它能在两个极端高速度网络优雅地表现,以及与广泛地部署的 TCP Reno 使公平体面和宽区域网络招待。快适合作为主要输入使用排队延期控制 TCP 拥挤窗户。包损失被用作一个第二等的信号适应地调整主要控制过程的参数。理论分析和试验性的结果证明算法的表演显著地作为与另外的最先进的算法相比被改进,当维持好公平时。 | Jingyuan WANG Jiangtao WEN Yuxing HAN Jun ZHANG Chao LI Zhang XIONG | 2014 | Frontiers of Computer Science2014，8，3： | 2 |
| 4 | SMER:a secure method of exchanging resources in heterogeneous internet of things显示文摘The number of IoT(internet of things)connected devices increases rapidly.These devices have different operation systems and therefore cannot communicate with each other.As a result,the data they collected is limited within their own platform.Besides,IoT devices have very constrained resources like weak MCU(micro control unit)and limited storage.Therefore,they need direct communication method to cooperate with each other,or with the help of nearby devices with rich resources.In this paper,we propose a secure method to exchange resources(SMER)between heterogeneous IoT devices.In order to exchange resources among devices,SMER adopts a compensable mechanism for resource exchange and a series of security mechanisms to ensure the security of resource exchanges.Besides,SMER uses a smart contract based scheme to supervise resource exchange,which guarantees the safety and benefits of IoT devices.We also introduce a prototype system and make a comprehensive discussion. | Yu ZHANG Yuxing HAN Jiangtao WEN | 2019 | Frontiers of Computer Science2019，13，6： | 2 |
| 5 | Weighted centroid localization algorithm:theoretical analysis and distributed implementation显示文摘 | Wang Jun Urriza P Han Yuxing | 2011 | Wireless Communications2011，10，10： | 1 |
| 6 | TCP-ACC: performance and analysis of an active congestion control algorithm for heterogeneous networks显示文摘 | Jun ZHANG Jiangtao WEN Yuxing HAN | 2017 | Frontiers of Computer Science2017，11，6： | 1 |
| 7 | Weighted centroid localization algorithm: theoretical analysis and distributed implementation 显示文摘 | WANG Jun URRIZA P HAN Yuxing | 2011 | IEEE Transactions on Wireless Communications2011，10，10： | 1 |
| 8 | Weighted Centroid localization algorithm: Theoretical analysis and distributed implementation显示文摘 | WANG Jun Urriza P HAN Yuxing | 2011 | IEEE Transactions on Wireless Communications2011，10，10： | 1 |
| 9 | Cadmium decreases crown root number by decreasing endogenous nitric oxide, which is indispensable for crown root primordia initiation in rice seedlings显示文摘 | Jie Xiong Han Lu Kaixing Lu Yuxing Duan Lingyao An Cheng Zhu | 2009 | Planta2009，，4： | 1 |
| 10 | Weighted centroid localization algorithm:theoretical analysis and distributed implementation显示文摘 | Wang Jun Urriza P Han Yuxing | 2011 | IEEE Transactions on Wireless Communications2011，10，10： | 1 |
| 11 | Weighted Centroid Localization Algorithm: Theoretical Analysis and Distributed Implementation 显示文摘 | Wang Jun Urriza P Han Yuxing | 2011 | IEEE Transactions on Wireless Communications2011，10，10： | 1 |
| 12 | Cadmium decreases crown root number by decreasing endogenous nitric oxide, which is indispensable for crown root primordia initiation in rice seedlings显示文摘 | Jie Xiong Han Lu Kaixing Lu Yuxing Duan Lingyao An Cheng Zhu | 2009 | Planta2009，，4： | 1 |
| 13 | Flexible Large-Area Graphene Films of 50-600 nm Thickness with High Carrier Mobility显示文摘Bulk graphene nanofilms feature fast electronic and phonon transport in combination with strong light-matter interaction and thus have great potential for versatile applications,spanning from photonic,electronic,and optoelectronic devices to charge-stripping and electromagnetic shielding,etc.However,large-area flexible close-stacked graphene nanofilms with a wide thickness range have yet to be reported.Here,we report a polyacrylonitrile-assisted’substrate replacement’strategy to fabricate large-area free-standing graphene oxide/polyacrylonitrile nanofilms(lateral size~20 cm).Linear polyacrylonitrile chains-derived nanochannels promote the escape of gases and enable macro-assembled graphene nanofilms(nMAGs)of 50-600 nm thickness following heat treatment at 3,000℃.The uniform nMAGs exhibit 802-1,540 cm^(2)V-1s-1carrier mobility,4.3-4.7 ps carrier lifetime,and>1,581 W m^(-1)K^(-1)thermal conductivity(n MAG-assembled 10μm-thick films,mMAGs).nMAGs are highly flexible and show no structure damage even after 1.0×10^(5)cycles of folding-unfolding.Furthermore,n MAGs broaden the detection region of graphene/silicon heterojunction from near-infrared to mid-infrared and demonstrate higher absolute electromagnetic interference(EMI)shielding effectiveness than state-of-the-art EMI materials of the same thickness.These results are expected to lead to the broad applications of such bulk nanofilms,especially as micro/nanoelectronic and optoelectronic platforms. | Shiyu Luo Li Peng Yangsu Xie Xiaoxue Cao Xiao Wang Xiaoting Liu Tingting Chen Zhanpo Han Peidong Fan Haiyan Sun Ying Shen Fan Guo Yuxing Xia Kaiwen Li Xin Ming Chao Gao | 2023 | Nano-Micro Letters2023，15，5： | 1 |
| 14 | Continuous-Wave Self-Focusing and Self-phase Modulation in C_(60)-Benzene Solution显示文摘C_(60)-benzene solutions are used as a new type of nonlinear Medium for observing cw self-focusing of laser beams.Self-phase modulation of much low power laser beam has been observed.The response time of C_(60)-benzene solution has been measured. | HAN Yanong ZHANG Weijun DONG Fengzhong XIA Yuxing ZANG Wencheng YANG Ping GU Gang DU Youwei FENG Duan | 1992 | Chinese Physics Letters1992，9，12： | 0 |
| 15 | All-and mixed-dielectric grating for Nd:glass-based high-energy pulse compression显示文摘Maximizing the energy-loading performance of gratings is a universal theme in high-energy pulse compression.However,sporadic grating designs strongly restrict the development of high-power laser engineering.This study proposes an all-and mixed-dielectric grating design paradigm for Nd:glass-based pulse compressors.The solution regions are classified according to the line density.High diffraction efficiency solutions are described in more detail based on the dispersion amount and incident angle.Moreover,an energy scaling factor of 7.09 times larger than that of the National Ignition Facility’s Advanced Radiographic Capability(NIF-ARC)is obtained by taking advantage of the low electric field intensity at transverse magnetic polarization and a small incident angle.These results make a pioneering contribution to facilitate future 20–50-petawatt-class ultrafast laser systems. | Yuxing Han Hongchao Cao Fanyu Kong Yunxia Jin Jianda Shao | 2023 | High Power Laser Science and Engineering2023，11，5： | 0 |
| 16 | Nearly-Resonant Two-Photon Absorption of C6o Thin Film at 633 nm显示文摘We present nieasureinents of two-pho ton absorption(TPA)coefficient of C_(60) thin Hhn at 633nm.Large values of β〜5cm/W were determined.Nearly~resona.nt TPA transition around 3.76eV absorption region was discussed. | HAN Yanong ZHANG Weijun GAO Xiaoming CUI Yiben XIA Yuxing GU Gang ZANG Wencheng DU Youwei FENG Duan | 1993 | Chinese Physics Letters1993，10，8： | 0 |
| 17 | Experimental Observation of Electrie Field Induced C_(60) Redistribution in Benzene Solution显示文摘We report the experimental observation of electric field induced Gso redistribution,in benzene solution by thermal blooming change of transmitted light.The pol&riz&tion of C_(60) molecules in external field is analyzed. | HAN Yanong GAO Xiaoming ZHANG Weijun DING Hongyu XIA Yuxing ZANG Wencheng GU Gang YANG Ping DU Youwei FENG Duan | 1993 | Chinese Physics Letters1993，10，11： | 0 |
| 18 | Experimental Study on Thermal Performance of FLNG Spiral Wound Heat Exchanger under Sloshing Conditions显示文摘The FLNG spiral wound heat exchanger(SWHE) is affected by the sea conditions, which leads to more complex flow process and decrease the heat transfer performance of the heat exchanger. In order to study the thermal performance of FLNG SWHE under heaving and swaying conditions, the experimental devices of FLNG SWHE and six-DOF(degree of freedom) sloshing platform were built. The effects of heaving and swaying motions on the pressure drop and heat transfer characteristics were analyzed at different sloshing amplitudes. The results showed that the heaving and swaying motions can cause the temperature rise and pressure fluctuation of SWHE, especially for swaying. The effect of sloshing on the heat transfer performance at the top of SWHE was greater than bottom. The pressure fluctuation percentage was within 7% and the amount of temperature change was less than 2℃, under the sloshing displacement among 120–255 mm. | YAN Yan SUN Chongzheng HAN Hui LI Yuxing | 2019 | Journal of Thermal Science2019，28，5： | 0 |
| 19 | Numerical Study of Heat Transfer Characteristic for Subcooled Falling Film outside the Shaped Tubes under Rolling Motion显示文摘The heat transfer performance of spiral wound heat exchanger used in the floating liquefied natural gas(FLNG)may be significantly affected by the sloshing conditions.In this paper,a three-dimensional numerical model combined with the dynamic mesh technology is conducted to study subcooled falling film heat transfer under static and sloshing conditions.The three-dimensional velocity distribution of the liquid film on the shell side is observed.The effects of cross-section shape of heat exchange tubes,Reynolds numbers and sloshing parameters on heat transfer characteristics are analyzed.The results indicate that the heat transfer performance of the egg-shaped tube is superior to that of the elliptical and circular tube under both static and sloshing conditions due to significant heat transfer improvement in the lower half of the tube.The heat transfer coefficients of three different kinds of tubes decrease under sloshing conditions.When the rolling amplitude is 6°,the average heat transfer coefficients of the circular tube,elliptical tube and egg-shaped tube are reduced by 2.1%,3.7%and 4.9%respectively.Under the current sloshing parameters,increasing the rolling amplitude,the heat transfer coefficients of three different tubes are slightly increased,while the sloshing period has little effect on heat transfer.The egg-shaped tube and elliptical tube are greatly affected by sloshing motion at the low Reynolds number,while the effect is relatively small at the high Reynolds number. | HAN Hui WANG Junqi WANG Shaowei LI Yuxing | 2023 | Journal of Thermal Science2023，32，3： | 0 |
| 20 | The molecular epidemiological study of colistin-only-sensitive strains in multi-drug resistant Acinetobacter baumannii显示文摘This paper reported the epidemiology of the colistin-only-sensitive Acinetobacter baumannii(COS-AB)in a tertiary teaching hospital in China.We analyzed the clinical data of 136 COS-AB isolates from June 2004 to May 2005 and collected 66 A.baumannii isolates in which 33 strains were COS-AB,and the rest were non-COS-AB.Random amplified polymorphic DNA(RAPD)analysis(primer ERIC2 and 272)showed that all COS-AB were identical,while pulsed-field gel electrophotesis(PFGE)analysis showed two separate genotypes of these COS-AB which were distinctly different from that of non-COS-AB.The COS-AB from burn wards showed the identical PFGE pattern which was distinguished from the genotype of COS-AB in other departments,mainly surgical systems.The cross-infection was severe and strict methods of disinfection and sterilization should be implemented.Meanwhile,the epidemiology of COS-AB in environment and patients should be closely monitored.The PFGE analysis is a reliable method of A.baumannii typing. | YANG Li HAN Lizhong SUN Jingyong YU Yunsong NI Yuxing | 2007 | Frontiers of Medicine2007，1，4： | 0 |
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