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| 1 | In vivo theranostics with near-infraredemitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration显示文摘Carbon dots that exhibit near-infrared fluorescence(NIR CDs)are considered emerging nanomaterials for advanced biomedical applications with low toxicity and superior photostability and targeting compared to currently used photoluminescence agents.Despite progress in the synthesis of NIR CDs,there remains a key obstacle to using them as an in vivo theranostic agent.This work demonstrates that the newly developed sulfur and nitrogen codoped NIR CDs are highly efficient in photothermal therapy(PTT)in mouse models(conversion efficiency of 59%)and can be readily visualized by photoluminescence and photoacoustic imaging.The real theranostic potential of NIR CDs is enhanced by their unique biodistribution and targeting.Contrary to all other nanomaterials that have been tested in biomedicine,they are excreted through the body’s renal filtration system.Moreover,after intravenous injection,NIR CDs are accumulated in tumor tissue via passive targeting,without any active species such as antibodies.Due to their accumulation in tumor tissue without the need for intratumor injection,high photothermal conversion,excellent optical and photoacoustic imaging performance,and renal excretion,the developed CDs are suitable for transfer to clinical biomedical practice. | Xin Bao Ye Yuan Jingqin Chen Bohan Zhang Di Li Ding Zhou Pengtao Jing Guiying Xu Yingli Wang Kateřina Holá Dezhen Shen Changfeng Wu Liang Song Chengbo Liu Radek Zbořil Songnan Qu | 2018 | Light(Science & Applications)2018，7，1： | 13 |
| 2 | Characteristics of dissolved organic matter in lakes with different eutrophic levels in southeastern Hubei Province,China显示文摘Dissolved organic matter(DOM)plays a crucial role in both the carbon cycle and geochemical cycles of other nutrient elements,which is of importance to the management and protection of the aquatic environments.To achieve a more comprehensive understanding the characteristics of DOM in the Changjiang(Yangtze)River basin,water samples from four natural lakes(Xiandao,Baoan,Daye,and Qingshan)in southeastern Hubei Province in China with different eutrophication levels were collected and analyzed.The optical characteristics were analyzed using ultraviolet-visible spectrophotometry and excitation-emission matrix spectroscopy coupled with parallel factor analysis.The results show that:(1)two humic-like components(C1 and C2)and two protein-like substances(C3 and C4)of DOM were identified in all waterbodies;(2)C3 originated primarily from the degradation of microalgae and contributed substantially to humic-like components during transformation.C4 was widely present in the Changjiang River basin and its formation was related to microbial activity,rather than algal blooms or seasons.Influenced by the water mixing,the protein-like components were more likely to be transformed by microorganism,whereas humic-like components were more easily to be photobleached;(3)the concentration of DOM and the fluorescence intensity of humic-like components gradually increased with rising lake eutrophication levels.With respect to protein-like components,only C3 showed changes along the eutrophication gradients;(4)DOM showed a high affinity with permanganate index(COD Mn)and chlorophyll a(chl a)while the relationship was variable with phosphorus.This study helps us systematically understand the DOM characteristics,microbial activities,and pollutant transformation in the Changjiang River basin and provides reference to the ecological restoration of aquatic environments. | Weixiang REN Xiaodong WU Xuguang GE Guiying LIN Mengdie ZHOU Zijie LONG Xinhui YU Wei TIAN | 2021 | Journal of Oceanology and Limnology2021，39，4： | 8 |
| 3 | Introduction of pokeweed antiviral protein cDNA into Brassica napus and acquisition of transgenic plants resistant to viruses显示文摘Using cotyledonary petioles as explants, the PAP cDNA controlled by wound-in-ducible promoter has been introduced into Brassica napus by coculture with Agrobacterium tumefaciens and laser microbeam puncture respectively. Regenerated plants resistant to gen-tamycin have been selected out. PCR amplification and Southern blotting analysis indicated that PAP cDNA together with wound-inducible promoter had been integrated into Brassica genome with transformation frequencies of 2.0% and 1.7% for two transformation methods respectively. The test of virus challenge showed that these transgenic Brassica plants were resistant in different degrees to mechanically inoculated TuMV. | ZHANG Haiyan , TIAN Yingchuan , ZHOU Yihua , DANG Benyuan LAN Haiyan , SONG Guiying , WANG Lanlan , LIU Guizhen , ZHANG Lihua and CHEN ZhenghuaInstitute of Genetics , Chinese Academy of Sciences , Beijing 100101, China Institute of Microbiology , Chinese Academy of Sciences , Beijing 100080, China | 1999 | Chinese Science Bulletin1999，44，8： | 3 |
| 4 | Electrochemical properties of carbon-coated LiFePO_4 and LiFe_(0.98)Mn_(0.02)PO_4 cathode materials synthesized by solid-state reaction显示文摘Olivine structured LiFePO 4 /C (lithium iron phosphate) and Mn 2+ -doped LiFe 0.98 Mn 0.02 PO 4 /C powders were synthesized by the solid-state reaction. The effects of manganese partial substitution and different carbon content coating on the surface of LiFePO 4 were considered. The structures and electrochemical properties of the samples were measured by X-ray diffraction (XRD), cyclic voltammetry (CV), charge/discharge tests at different current densities, and electrochemical impedance spectroscopy (EIS). The electrochemical properties of LiFePO 4 cathodes with x wt.% carbon coating (x= 3, 7, 11, 15) at =0.2C, 2C (1C= 170 mAh·g 1 ) between 2.5 and 4.3 V were investigated. The measured results mean that the LiFePO 4 with 7 wt.% carbon coating shows the best rate performance. The discharge capacity of LiFe 0.98 Mn 0.02 PO 4 /C composite is found to be 165 mAh·g 1 at a discharge rate, = 0.2C, and 105 mAh·g 1 at =2C, respectively. After 10 cycles, the discharge capacity has rarely fallen, while that of the pristine LiFePO 4 /C cathode is 150 mAh·g 1 and 98 mAh·g 1 at =0.2 and 2C, respectively. Compared to the discharge capacities of both electrodes above, the evident improvement of the electrochemical performance is observed, which is ascribed to the enhancement of the electronic conductivity and diffusion kinetics by carbon coating and Mn 2+-substitution. | Lin, Ying Zeng, Baozhi Lin, Yingbin Li, Xiaowei Zhao, Guiying Zhou, Ting Lai, Heng Huang, Zhigao | 2012 | Rare Metals2012，31，2： | 3 |
| 5 | Comparison on the leaching kinetics of chalcocite and pyrite with or without bacteria显示文摘The acid leaching,ferric leaching,and bioleaching of chalcocite and pyrite minerals were conducted in two sets of 3L stirred reactors.The dissolution rates of copper and iron were correlated with leaching conditions.In the acid leaching process,the dissolution rate of chalcocite was around 40wt.% while that of pyrite was less than 4%.In the ferric leaching process with high ferric concentration,only 10 wt.% of iron in pyrite was leached out at the same retention time though the copper recovery over 60 wt.% in chalcocite.For the bioleaching process,the chalcocite leaching rate was highly increased,nearly 90 wt.% of copper was leached out,and the iron dissolution of pyrite exceeded 70 wt.%.For the two minerals,the bioleaching shows the highest leaching rate compared with the acid leaching or ferric leaching.In uncontrolled bioleaching process,pyrite could be dissolved effectively.The experimental data were fitted to the shrinking core and particle model.The results show that in all the leaching tests,the chalcocite leaching was mainly controlled by diffusion,while for the pyrite leaching,chemical reaction is the main rate-determining step. | RUAN Renman ZHOU E LIU Xingyu WU Biao ZHOU Guiying WEN Jiankang | 2010 | Rare Metals2010，29，6： | 3 |
| 6 | Evaluation of the Development of Circular Agriculture in Chongqing City Based on Entropy Method显示文摘The circular agriculture is conducive to achieving the purpose of efficient agricultural economy and environment- friendliness.Based on the perspective of circular agriculture theory,this paper builds the evaluation indicator system for circular agriculture,and uses entropy method and Matlab analysis tool to carry out the comprehensive evaluation of the level of agricultural development in Chongqing City during the period 2003- 2012. It analyzes the obstacles to the development of circular agricultural economy in Chongqing City in 2012,and finally puts forward the corresponding recommendations. | Fangying ZHOU Shunqiang SUN Guiying ZHU | 2014 | Asian Agricultural Research2014，6，9： | 2 |
| 7 | Organosilicon modified method to improve Li^+ storage capacity of graphene oxide (GO)显示文摘Organosilicon modified reduced graphene oxide(Mr GO) has been fabricated by direct organosilicon modification of graphene oxide(GO). Interestingly,it is observed that 3D rGO-like structures occurred after directly carrying out the organosilicon modification on the surface of GO. The obtained organosilicon Mr GO displays the more remarkable improvement of electrochemical performances than GO,which was verified by electrochemical measurements in detail. For instance,the organosilicon MrGO shows the cycling performances at 901 mA hg^-1 after 200 cycles at 0.1 Ag^-1 and 446 mA hg^-1 after 300 cycles at 2.0 Ag^-1,respectively. These results unveil that organic modification method is an effective way to improve the Li^+ storage capacity of general carbon materials. | WANG Kun JU DongYing XU GuiYing HAN BeiBei CHAI MaoRong WANG YingXin Li LiXiang ZHANG XueHu UCIDA Masaya ZHOU WeiMin | 2020 | Science China(Technological Sciences)2020，63，12： | 2 |
| 8 | On the Embodiment of Economy Principle in the English Language显示文摘 | Guiying Zhou | 2012 | English Language and Litera- ture Studies2012，2，2： | 1 |
| 9 | Comparative study of the eliminating of waste gas containing toluene in twin biotrickling filters packed with molecular sieve and polyurethane foam 显示文摘 | He Ze Zhou Lincheng Li Guiying | 2009 | J Hazard Mater2009，167，13： | 1 |
| 10 | Effects of different milling methods on flour quality and performance in steamed breadmaking 显示文摘 | Sun Lijuan Zhou Guiying Zhi Guoan | 2007 | Journal of Cereal Science2007，45，： | 1 |
| 11 | Synthesis and characterization of novel magnetic Fe3O4/polyurethane foam composite applied to the carrier of immobilized microorganisms for wastewater treatment显示文摘 | Lincheng Zhou Guiying Li Taicheng An Yanfeng Li | 2010 | Research on Chemical Intermediates2010，，3： | 1 |
| 12 | Effect of heavily doping with boron on electronic structures and optical properties of β-SiC 显示文摘 | Feng Guiying Fang Xiaoyong Wang Junjun Zhou Yan Lu Ran Yuan Jie Cao Maosheng | 2010 | Physica B: Condensed Matter2010，405，12： | 1 |
| 13 | Effects of different milling methods on flour quality and performance in steamed breadmaking显示文摘 | Sun Lijuan Zhou Guiying Zhi Guoan Li Zaigui | 2007 | Journal of Cereal Science2007，，45： | 1 |
| 14 | Construction of the first high-density genetic map for growth related QTL analysis in Ancherythroculter nigrocauda显示文摘Ancherythroculter nigrocauda is a fish endemic to the upper areas of the Changjiang(Yangtze)River in China.Quantitative trait locus(QTL)mapping is a powerful tool to identify potential genes affecting traits of economic importance in domestic animals.In this study,a high-density genetic map was constructed with 5901 single nucleotide polymorphism(SNP)makers by sequencing 92 individual fish from a F1 family using the specific-locus amplified fragment sequencing approach.Initially,48 QTLs for total length,body length,body height,and body weight were identified according to the high density of the genetic map with 24 LGs,a total length of 3839.4 cM,and marker spacing of about 0.82 cM.These QTLs explained 27.1%-49.9%of phenotypic variance.The results of this study suggest that major QTLs are responsible for the growth of A.nigrocauda,and these are potentially useful in comparative genomics research,genome assembly,and marker-assisted breeding programs for this species. | Yanhong SUN Pei LI Guiying WANG Renli SUN Jian CHEN Qi ZHOU Jingou TONG Qing LI | 2021 | Journal of Oceanology and Limnology2021，39，3： | 1 |
| 15 | Isolation, Identification, and Quantitative Determination of Saponin in Apostichopus japonicus by HPLC-DAD显示文摘Apostichopus japonicus is an important invertebrate that is widely used as a tonic food in Asian countries.The purpose of this study is to purify and identify a class of compound,the saponins,from the body wall of A.japonicus,and to establish a new me-thod to determine the quantity of saponins in the sea cucumber.In this study,the saponins of A.japonicus,cladoloside A(CA),were ob-tained from 80%ethanol extract by column chromatography for the first time and were characterized using the spectral method.The resulting purified saponins were then profiled using ^(1)HNMR,^(13)CNMR,and ESI-MS,which revealed the CA molecular formula of C_(53)H_(82)O_(2) and contained a triterpenoid backbone,a methylglucopyranosyl moiety,a quinovopyranosyl,and two xylopyranosyls.A me-thod for the quantitative determination of CA,comprising microwave-assisted extraction,high-performance liquid chromatography,and diode array detector method,was established.Extraction efficiency was optimized by changing microwave power,extraction sol-vent,volume,time,and temperature.Results showed that under the optimum conditions(extraction time of 10 min,temperature of 45℃,and solvent of 25 mL 70%ethanol under 400 W),the detection limit of CA was 0.0015 mg mL^(−1),and the recoveries of CA from samples at spiking levels of 10,20,and 50μg g^(−1) ranged from 90.1%-104%.The proposed method was successfully applied to ana-lyze the saponins in different tissues of A.japonicus collected in different seasons.The method developed in this study can provide quantitative technical support for the quality control of A.japonicus. | LIU Guiying WANG Xuda GE Kun WU Jinhao WANG Zhaohui DU Jing SONG Lun ZHOU Zunchun | 2022 | Journal of Ocean University of China2022，21，2： | 1 |
| 16 | Effects of different milling methods on flour quality and performance in steamed breadmaking 显示文摘 | SUN Lijuan ZHOU Guiying ZHI Guoan | 2007 | Journal of Cereal Science2007，45，1： | 1 |
| 17 | Compara- tive study of the eliminating of waste gas containing toluene in twin biotrickling filters packed with molecular sieve and polyurethane foam 显示文摘 | He Ze Zhou Lincheng Li Guiying | 2009 | J Hazard Materi2009，167，123： | 1 |
| 18 | The measurement of responsivity of infrared photodetectors using a cavity blackbody显示文摘For the measurement of responsivity of an infrared photodetector,the most-used radiation source is a blackbody.In such a measurement system,distance between the blackbody,the photodetector and the aperture diameter are two parameters that contribute most measurement errors.In this work,we describe the configuration of our responsivity measurement system in great detail and present a method to calibrate the distance and aperture diameter.The core of this calibration method is to transfer direct measurements of these two parameters into an extraction procedure by fitting the experiment data to the calculated results.The calibration method is proved experimentally with a commercially extended InGaAs detector at a wide range of blackbody temperature,aperture diameter and distance.Then proof procedures are further extended into a detector fabricated in our laboratory and consistent results were obtained. | Nong Li Dongwei Jiang Guowei Wang Weiqiang Chen Wenguang Zhou Junkai Jiang Faran Chang Hongyue Hao Donghai Wu Yingqiang Xu Guiying Shen Hui Xie Jingming Liu Youwen Zhao Fenghua Wang Zhichuan Niu | 2023 | Journal of Semiconductors2023，44，10： | 0 |
| 19 | Joint Toxicity Determination of Clopyralid,Picloram and Benazolin Mixtures on Broad-leaved Weed Lapsana apogonoides Maxim.in Rape Fields显示文摘[Objectives]This study was conducted to investigate the compounding of three herbicides:clopyralid,picloram and benazolin,so as to improve the effectiveness of herbicides.[Methods]With Lapsana apogonoides Maxim.as the target and clopyralid,picloram and benazolin as the test agents,seven gradient concentrations were set up to determine the joint toxicity of the three agents.[Results]When the compounding ratio of picloram,clopyralid and benazolin was 2∶1∶6,the maximum co-toxicity coefficient was 290.0.[Conclusions]The compounding of picloram,clopyralid and benazolin has a significant synergistic effect on L.apogonoides,which reduces production costs and environmental pressure,providing technical support for the effective control of broad-leaved weeds such as L.apogonoides. | Xiong LI Jingbo LI Huifang DENG Yunyun ZHOU Kaifa GUO Xiongmei ZHU Chenzhong JIN Guiying LIU | 2021 | Agricultural Biotechnology2021，10，5： | 0 |
| 20 | Study on the Optimization of Extraction Technology of Rose laevigate Michx. Polysaccharides and Its in vitro Antioxidant Activity显示文摘[Objectives]This study was conducted to optimize the optimal process conditions for extracting polysaccharides from Rose laevigate Michx.with hot water.[Methods]The extraction rate of R.laevigate was used as an evaluation index,and extraction temperature,material-to-liquid ratio,extraction time and extraction times were selected as influencing factors.On the basis of single factor tests,L 9(34)orthogonal tests were carried out for optimization,and the content of polysaccharides was determined by the phenol-sulfuric acid method.The in vitro antioxidant activity of the extracted R.laevigate polysaccharides was studied.[Results]The effects of various influencing factors on the extraction rate of R.laevigate polysaccharides ranked as material-liquid ratio>extraction temperature>extraction times>extraction time.The optimal extraction process was extraction temperature 80℃,extraction time 2 h,and material-to-liquid ratio 1∶25,extraction times 3 times,under which the extraction rate was(9.55±0.12)%.R.laevigate polysaccharides had certain scavenging capacities of DPPH free radicals and hydroxyl free radicals,and its scavenging capacity of DPPH free radicals was better than that of hydroxyl free radicals.[Conclusions]This study provides a theoretical basis for the optimization of the extraction process of R.laevigate polysaccharides and the in-depth development and application of polysaccharides. | Guochen HU Han LIU Qianqian TANG Li CHENG Chenzhong JIN Yunyun ZHOU Xuejiao ZHANG Guiying LIU | 2021 | Agricultural Biotechnology2021，10，6： | 0 |
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