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| 1 | Circulating MicroRNA-145 is Associated with Acute Myocardial Infarction and Heart Failure显示文摘 | Ming Zhang Yun-Jiu Cheng Jaskanwal DS Sara Li-Juan Liu Li-Ping Liu Xin Zhao Hai Gao | 2017 | Chinese Medical Journal2017，，1： | 23 |
| 2 | 术中应用荧光素钠有利于胶质母细胞瘤浸润边缘的手术切除(英文)显示文摘Objective Extent of resection is an important prognostic factor in patients undergoing surgery for glioblastoma( GBM).Recent evidence suggests that intravenously administered fluorescein sodium associates with tumor tissue,facilitating safe maximal resection of GBM. In this study,the authors evaluate the safety and utility of intraoperative fluorescein guidance for the prediction of histopathological alteration both in the contrast-enhancing( CE) regions,where this relationship has been established,and into the nonCE( NCE),diffusely infiltrated margins. Methods Thirty-two patients received fluorescein sodium( 3 mg/kg) intravenously prior to resection. Fluorescence was intraoperatively visualized using a Zeiss Pentero surgical microscope equipped with a YELLOW 560 filter.Stereotactically localized biopsy specimens were acquired from CE and NCE regions based on preoperative MRI in conjunction with neuronavigation. The fluorescence intensity of these specimens was subjectively classified in real time with subsequent quantitative image analysis,histopathological evaluation of localized biopsy specimens,and radiological volumetric assessment of the extent of resection.Results Bright fluorescence was observed in all GBMs and localized to the CE regions and portions of the NCE margins of the tumors,thus serving as a visual guide during resection. Gross-total resection( GTR) was achieved in 84% of the patients with an average resected volume of 95%,and this rate was higher among patients for whom GTR was the surgical goal( GTR achieved in 93. 1% of patients,average resected volume of 99. 7%). Intraoperative fluorescein staining correlated with histopathological alteration in both CE and NCE regions,with positive predictive values by subjective fluorescence evaluation greater than 96% in NCE regions. Conclusions Intraoperative administration of fluorescein provides an easily visualized marker for glioma pathology in both CE and NCE regions of GBM. These findingssupport the use of fluorescein as a microsurgical adjunct for guiding GBM resection to facilitate safe maximal removal. | Neira JA Ung TH Sims J Malone HR Chow DS Samanamud JL Zanazzi GJ Guo X Bowden SG Zhao B Sheth SA McKhann GM 2nd Sisti MB Canoll P D'Amico RS Bruce JN | 2016 | 中华神经外科疾病研究杂志2016，15，5： | 2 |
| 3 | Structure and design of potent and selective cathepsin K inhibitors显示文摘 | Yamashita DS Smith WW Zhao B | 1997 | J Am Chem Soc1997，119，11： | 1 |
| 4 | Supplemental L-arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury显示文摘 | Sato H Zhao ZQ Mcgee DS | 1995 | J Thorac Cardiovasc Surg1995，110，2： | 1 |
| 5 | NF-kappaB dysregulation in mieroRNA-146a-deficient mice drives the development of myeloid malignancies显示文摘 | Zhao JL Rao DS Boldin MP | 2011 | Proc Natl Acad Sci USA2011，108，22： | 1 |
| 6 | Peripheral T cells overexpress MIP-lalpha to enhance its transendothelial migration in Alzheimer's disease.显示文摘 | Man SM Ma YR Shang DS Zhao WD Li B Guo DW Fang WG Zhu L Chert YH | 2006 | 中国生物学文摘2006，20，9： | 1 |
| 7 | Bailing capsule in preventingepithelial-mesenchymal transition in rats with tubul0interstitial fibrosis显示文摘 | Zhao DA Yang DS Bi LY | 2005 | J Appl Clin Pediatr2005，20，9： | 1 |
| 8 | Randomized controlled trial of patching vs acupuncture for anisometropic amblyopia in children aged 7 to 12 years显示文摘 | Zhao J Lam DS Chen LJ Wang Y Zheng C Lin Q | | 0，，12： | 1 |
| 9 | Effect of AT1 receptor blockade on cardiac collagen remodeling after myocardial infarction 显示文摘 | Ju H Zhao S Jassal DS | 1997 | Cardiovascular Research1997，35，2： | 1 |
| 10 | High throughput screening of disulfide-containing proteins in a complex mixture 显示文摘 | Zhao DS Gregorich ZR Ge Y | 2013 | Proteomics2013，13，22： | 1 |
| 11 | Particularly interesting new cysteine- histidine rich protein expression in eoloreetal adenoearcinomas 显示文摘 | Zhao ZR Zhang ZY Cui DS | 2006 | World J Gastroenterol2006，12，2： | 1 |
| 12 | MicroRNA function in myeloid biology显示文摘 | O' Connell RM Zhao JL Rao DS | 2011 | Blood2011，118，11： | 1 |
| 13 | Aberrant expression of miR-20a and miR-203 in cervical eancer显示文摘 | Zhao S Yao DS Ding N | 2013 | Asian Pac J Cancer Prey2013，14，4： | 1 |
| 14 | NF-kappaB dysregula- tion in microRNA-146a-deficient mice drives the development of myeloid malignancies显示文摘 | Zhao JL Rao DS Boldin MP | 2011 | Proc Natl Acad Sci USA2011，108，： | 1 |
| 15 | MFEprimer:multiple factor evaluation of the specificity of PCR primers显示文摘 | Qu WB Shen ZY Zhao DS | 2009 | Bioinformatics2009，25，2： | 1 |
| 16 | Effect of AT1 R receptor blockade on cardiac collagen remodeling after myocardial infarction显示文摘 | Ju HS Zhao SF Jassal DS | 1997 | Cardiovasc Res1997，35，2： | 1 |
| 17 | NF-κ B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies显示文摘 | Zhao J Rao DS Boldin MP | 2011 | Proc Natl Acad Sci U S A2011，108，22： | 1 |
| 18 | Supplemental L - arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury 显示文摘 | Sato H Zhao ZQ McGee DS | 1995 | J Thorac Cardiocass Surg1995，110，： | 1 |
| 19 | Amyloid beta interaction with receptor for advanced glycation end products up-regulates brain endothelial CCR5 expression and promotes T cells crossing the bloodbrain barrier 显示文摘 | Li M Shang DS Zhao WD | 2009 | J Immunol2009，182，9： | 1 |
| 20 | Randomized controlled trial of patching vs acupuncture for anisometropic amblyopia in childrenaged 7 to 12 years显示文摘 | Zhao J Lam DS Chen LJ | 2010 | Areh Ophthalmo12010，128，12： | 1 |
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