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| 1 | LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration显示文摘新兴的研究在少些在染色质水平,但是相对调整基因表示记录长非编码的 RNA (LncRNAs ) 的角色被知道他们怎么调整 DNA methylation。这里,我们识别 lncRNA, Dum (发展联系 pluripotency 2 (Dppa2 ) 在上游的有约束力的肌肉 lncRNA ) 在骨胳的 myoblast 房间。Dum 的表示动态地在 vitro 并且在 vivo 在 myogenesis 期间被调整。它被在 myoblast 区别之上有约束力的 MyoD transcriptionally 也导致。功能的分析证明它支持 myoblast 区别和导致损坏的肌肉新生。机械学地, Dum 被发现它的附近的基因到沉默, Dppa2,在通过招募的 cis Dnmt1, Dnmt3a 和 Dnmt3b。而且, intrachromosomal 在 Dum 地点和 Dppa2 倡导者之间循环为 Dum/Dppa2 相互作用是必要的。一起,我们识别了与 Dnmts 交往调整 myogenesis 的新奇 lncRNA。 | Lijun Wang Yu Zhao Xichen Bao Xihua Zhu Yvonne Ka-yin Kwok Kun Sun Xiaona Chen Yongheng Huang Ralf Jauch Miguel A Esteban Hao Sun Huating Wang | 2015 | Cell Research2015，25，3： | 34 |
| 2 | Tuning sol size to optimize organosilica membranes for gas separation显示文摘A series of organosilica sols are prepared by the polymeric sol–gel method using 1,2-bis(triethoxysilyl)ethane(BTESE)as the precursor.Particle size distributions of the BTESE-derived sols are systematically investigated by carefully adjusting the synthesis parameters(i.e.,water ratios,acid ratios and solvent ratios)in the sol process.In certain conditions,increasing the water ratio or the acid ratio tends to cause larger sol sizes and bimodal particle size distributions.However,higher solvent ratios lead to smaller sol sizes and unimodal particle size distributions.The organosilica membranes prepared from the optimized sols show excellent H_2 permeances(up to 4.2×10^(-7)mol·m^(-2)·s^(-1)·Pa^(-1))and gas permselectitivies(H_2/CO_2 is 9.5,H_2/N_2 is 50 and H_2/CH_4 is 68).This study offers significant insights into the relationship between the sol synthesis parameters,sol sizes and membrane performance. | Huating Song Yibin Wei Chenying Wang Shuaifei Zhao Hong Qi | 2018 | Chinese Journal of Chemical Engineering2018，26，1： | 3 |
| 3 | Biological indicators of sub-optimal health status显示文摘OBJECTIVE:To investigate biological indicators of sub-optimal health status and provide means of objective assessment of sub-optimal health status.METHODS:We set the unified standards for diagnosing a SHS.We tested various laboratory indicators in 407 cases that we selected randomly from2807 subjects and collected 15 mL of fasting venous blood from each case.We measured serum immunoglobulin A(IgA)and immunoglobulin G(IgG)concentrations,serum beta endorphins(β-EP),cortisol(C),testosterone(T),plasma adrenocorticotropic hormone(ACTH)and serum T lymphocyte subsets CD3+and CD4+.RESULTS:Mean serum testosterone concentrations and their ratio to cortisol(C)concentrations weresignificantly higher in the healthy group than in those with sub-optimal health status(P<0.01).Mean serum CD3+concentrations were significantly higher in those with sub-optimal health status than in the healthy group(P<0.05).CONCLUSION:Decreased serum testosterone/cortisol ratio may be an objective indication of sub-optimal health status.Changes in neuroendocrine and immunological indicators may explain some of the symptoms,including malaise and poor work performance,attributable to persistent or relapsing fatigue in subjects with sub-optimal health status. | Limin Wang Xin Zhao Jiaxu Chen Xiaoling Guo Xin Liang Danhui Yi Huating Cui Yueyun Liu | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 1 |
| 4 | Study of Water Treatment Residue Used as a Profile Control Agent显示文摘从水处理过程的大量残余逐渐地在 waterflood 油矿积累了并且因此引起了严肃的环境污染。水处理残余是灰暂停,与 1.08 g/cm3 的密度,并且主要包含超过 65% 轻 CaCO3, MgCO3, CaSO4, Fe2S3 和 Ca (哦) 2。这份报纸在油矿在核心渗透和它的申请上查明水处理残余的效果。实验室的 Coreflooding 测试在二个人工的核心和一个自然核心被进行。核心变化被演员组模型图象分析,水银注射方法和扫描电子显微镜学(SEM ) 评估。新鲜的水被注入另一个自然核心,它与水处理残余被插,到决定有效 life.The 结果显示水处理残余有一个强烈插的能力,到侵蚀的一个电阻和长有效的生活,并且因此,它能为侧面 control.In 被用作便宜原料过去的 8 年,水处理残余的 60,164 m3 的一个总数被用于 151 个井处理的侧面控制,与98%的成功比率和 effecti 在地测试,侧面控制代理人增加了注射者的开始的压力和注射压力,并且减少明显的水 injectivity 系数,显著地改善的吸入侧面和变长的一般水准满足注射者的生活。28,381 大量另外的油从这些相应油井被恢复,与 3,069.55 潨敬 ? 湩匠 ? 挠湡映捡汩瑩瑡 ? 敤票牤瑡潩的经济好处吗? | Hou Tianjiang Zhao Huating Li Zongtian Zhao Puchun Xiao Liping | 2005 | Petroleum Science2005，2，4： | 0 |
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