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1湖南省武岗市洞口县狂犬病流行病学研究显示文摘目的分析2003-2004年问在湖南省武岗市与洞口县发生的狂犬病并探讨局部地区流行的因素。方法对狂犬病进行个案调查,用直接免疫荧光法检测犬脑组织中的狂犬病毒抗原,用RT-PCR法扩增N基因片段,测定核苷酸序列并构建系统发生树进行遗传特征分析。结果自1991-2002年武岗市与洞口县仅各报告1例人狂犬病,但2003-2004年间,分别报告30例人狂犬病。62例狂犬病患者中61例被犬所伤,1例被猫所伤。在有完整记录的50例患者中,平均潜伏期为44.18天。其中7例(14%)狂犬病患者的潜伏期≤15天,16例(32%)潜伏期≤20天。在疫点周围采集的99只犬脑组织中,13只犬脑组织狂犬病毒抗原阳性,阳性率为13.13%。将Wg13与Dk13株病毒的部分N基因核苷酸序列与已报道中国病毒株比较,发现2株病毒与广西及安徽的毒株有最高的同源性,构建的系统发生树也分在同一分支。用全N基因核苷酸序列分析发现,Wg13与Dk13毒株全为I型狂犬病毒,2株病毒之间的同源性为99.4%以上。比较分析2株病毒N基因编码的氨基酸序列,发现包括第Ⅳ抗原位点区在内的多个氨基酸位点发生了氨基酸的替代。结论引起武岗市与洞口县的狂犬病流行的病毒不是新型狂犬病毒,犬饲养量大与病毒携带率高是狂犬病暴发的直接原因。张永振 熊成龙 邹洋 李明慧 肖奇友 王祥迪 唐茂晟 杨安保 朱学识 陈碧云 ZhenFU 2006中华流行病学杂志2006,27,7:43
2Survey of information security显示文摘The 21st century is the age of information when information becomes an important strategic resource. The information obtaining, processing and security guarantee capability are playing critical roles in comprehensive national power, and information security is related to the national security and social stability. Therefore, we should take measures to ensure the information security of our country. In recent years, momentous accomplishments have been obtained with the rapid development of information security technology. There are extensive theories about information security and technology. However, due to the limitation of length, this article mainly focuses on the research and development of cryptology, trusted computing, security of network, and information hiding, etc.SHEN ChangXiang ZHANG HuangGuo FENG DengGuo CAO ZhenFu HUANG JiWu 2007Science in China(Series F)2007,50,3:39
3Nanobubble generation and its application in froth flotation (part I): nanobubble generation and its effects on properties of microbubble and millimeter scale bubble solutions显示文摘A special nanobubble generation system has been developed for evaluating the effect of nanobubble on froth flotation. In this study, an eight-factor five-level Central Composite Experimental Design was conducted for investigating eight important parameters governing the median size and the volume of nanobubbles. These process parameters included surfactant concentration, dissolved oxygen (O2) content, dissolved carbon dioxide gas (CO2) content, pressure drop in cavitation tube nozzle, <50 nm hydrophobic particle concentration, <50 nm hydrophilic particle concentration, slurry temperature and the time interval after nanobubble generation. The properties, stability and uniformity of nanobubbles were investigated. The study of the produced nanobubble’s effects on the characteristics of microbubble solutions and millimeter scale bubble solutions was performed in a 50.8 mm column.FAN Maoming TAO Daniel HONAKER Rick LUO Zhenfu 2010Mining Science and Technology2010,20,1:34
4Efficient Certificateless Authenticated Key Agreement Protocol from Pairings显示文摘In the area of secure Web information system, mutual authentication and key agreement are essential between Web clients and servers. An efficient certificateless authenticated key agreement protocol for Web client/server setting is proposed, which uses pairings on certain elliptic curves. We show that the newly proposed key agreement protocol is practical and of great efficiency, meanwhile, it satisfies every desired security requirements for key agreement protocols.WANG Shengbao CAO Zhenfu WANG Licheng 2006Wuhan University Journal of Natural Sciences2006,11,5:23
5The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China.Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao 2016Translational Neurodegeneration2016,5,1:23
6Olive leaf extract inhibits lead poisoning-induced brain injury显示文摘Olive leaves have an antioxidant capacity,and olive leaf extract can protect the blood,spleen and hippocampus in lead-poisoned mice.However,little is known about the effects of olive leaf extract on lead-induced brain injury.This study was designed to determine whether olive leaf extract can inhibit lead-induced brain injury,and whether this effect is associated with antioxidant capacity.First,we established a mouse model of lead poisoning by continuous intragastric administration of lead acetate for 30 days.Two hours after successful model establishment,lead-poisoned mice were given olive leaf extract at doses of 250,500 or 1000 mg/kg daily by intragastric administration for 50 days.Under the transmission electron microscope,olive leaf extract attenuated neuronal and capillary injury and reduced damage to organelles and the matrix around the capillaries in the frontal lobe of the cerebral cortex in the lead-poisoned mice.Olive leaf extract at a dose of 1000 mg/kg had the greatest protective effect.Spectrophotometry showed that olive leaf extract significantly increased the activities of superoxide dismutase,catalase,alkaline phosphatase and acid phosphatase,while it reduced malondialdehyde content,in a dose-dependent manner.Furthermore,immunohistochemical staining revealed that olive leaf extract dose-dependently decreased Bax protein expression in the cerebral cortex of lead-poisoned mice.Our findings indicate that olive leaf extract can inhibit lead-induced brain injury by increasing antioxidant capacity and reducing apoptosis.Yu Wang Shengqing Wang Wenhui Cui Jiujun He Zhenfu Wang Xiaolu Yang 2013Neural Regeneration Research2013,8,22:21
7Medusoid Fossils from the Sinian Xingmincun Formation of Southern Liaoning Province显示文摘Abundant medusoid soft-bodied metazoan fossils have been found in the Sinian Xingmincun Formation(with an isotopic age of 650 Ma) at Qipanmo, Qidingshan and Yangtun of the Dalian-Jinzhou area, southern Liaoning Province; in addition, a number of macroscopic algal fossils have been discovered for the first time in the Getun Formation overlying the Xingmincun Formation. Medusoid fossils include 3 genera and 6 species(all of which are new). Judging from their biological characters, these medusoid fossils are considered to have an intimate affinity with the Ediacara fauna in the terminal Precambrian of Australia, as their characters are close to each other. The authors suggest that these medusoids and the Edicara fauna might be the products of the same period. The discovery of the medusoid fauna in the Xingmincun Formation marks an important event in the evolution of the terminal Precambrian organisms in China, and it is of major practical significance in the study of the Sinian System of China and the correlation of the Sinian strata of northern and southern China.Hong Zuomin, Huang Zhenfu, Yang Xinde, Lan Jing, Xian Bingcai, Yang Yajun, Regional Geological Survey Party, Bureau of Geology and Mineral Resources of Liaoning Province, Jinzhou, Liaoning and Liu Xiaoliang Shenyang Institute of Geology and Resources, Chinese Academy of Geological Sciences, Shenyang, Liaoning Fang Xinzhong 1989Acta Geologica Sinica(English Edition)1989,63,1:20
8Nanobubble generation and its applications in froth flotation(partⅢ):specially designed laboratory scale column flotation of phosphate显示文摘Froth flotation is used widely for upgrading raw phosphate.The flotation recovery of coarse phosphate(-1.18+0.425 mm) is much lower than that achieved on the-0.425+0.15 mm size fraction.Enhanced recovery of coarse phosphate particles is of great economic and environmental importance for phosphate industry.In this investigation,four different phosphate samples were aquired,characterized and tested in a specially designed laboratory-scale flotation column.Significant recovery improvement of coarse phosphate flotation was achieved using cavitation-generated nanobubble though its effects differ among the four testing phosphate samples.The laboratory-scale flotation column test results indicate that nanobubble increased P_2O_5 recovery by up to 10%~30%for a given Acid Insoluble(A.I.) rejection,depending on the characteristic of phosphate samples.The improvement effect of nanobubble on the hard-to-float particles was more significant than that on easy-to-float particles,especially at lower collector dosages.Nanobubbles reduced the collector dosage by 1/3 to 1/2.Nanobubbles almost doubled the coarse phosphate flotation rate constant and increased the flotation selectivity index by up to 25%.FAN Maoming TAO Daniel HONAKER Rick LUO Zhenfu 2010Mining Science and Technology2010,20,3:18
9Nanobubble generation and its applications in froth flotation(part IV):mechanical cells and specially designed column flotation of coal显示文摘Coal is the world's most abundant fossil fuel.Coal froth flotation is a widely used cleaning process to separate coal from mineral impurities.Flotation of coarse coal particles,ultrafine coal particles and oxidized coal particles is well known to be difficult and complex.In this paper,the nanobubbles' effects on the flotation of the varying particle size,particle density and floatability coal samples were evaluated using a bank of pilot scale flotation cells,a laboratory scale and a pilot scale specially designed flotation column.The parameters evaluated during this study include the flow rate ratio between the nanobubble generator and the conventional size bubble generator,the superficial air velocity,collector dosage,frother concentration,flotation feed rate,feed solids concentration,feed particle size,and the superficial wash water flow rate,etc.The results show that the use of nanobubbles in a bank of mechanical cells flotation and column flotation increased the flotation recovery by 8%~27% at a given product grade.Nanobubbles increased the flotation rate constants of 600~355,355~180,180~75,and 75~0 microns size coal particles by 98.0%,98.4%,50.0% and 41.6%,respectively.The separation selectivity index was increased by up to 34%,depending on the flotation feed characteristics and the flotation conditions.FAN Maoming TAO Danie HONAKER Rick LUO Zhenfu 2010Mining Science and Technology2010,20,5:18
10Motion behavior of particles in air-solid magnetically stabilized fluidized beds for separation显示文摘In order to study the settling mechanism of particles in an air-solid magnetically stabilized fluidized bed(MSFB) for separation,we carried out free settling and quasi-zero settling tests on the tracing particles.The results show that the main resistance forces as the tracing particles settled in an air-solid MSFB were motion resistance force and yield force.The motion resistance and yield forces greatly hindered the free settling of the particles by greatly decreasing the acceleration for settling process of the particles.The acceleration decreased from 3022.62 cm/s 2 to zero in 0.1 s,and in the end,the particles stopped in the air-solid MSFB.The yield force on particles increased with increasing the magnetic field intensity,resulting in decrease of the quasi-zero settling displacement.However,the yield force on particles decreased with increasing the fluidized air velocity,leading to increase of the quasi-zero settling displacement.When the structure and operating parameters of the air-solid MSFB were set up,the yield stress on particles stopped in an air-solid MSFB was a function of diameter and density of particles.The settling displacements of equal diameter particles increased with increasing their densities,and the settling displacements of equal density particles increased with increasing their diameters.Song Shulei a,,Zhao Yuemin a,Luo Zhenfu a,Tang Ligang b a School of Chemical Engineering and Technology,China University of Mining & Technology,Xuzhou 221116,China b Coal Mining and Designing Department,Tiandi Science & Technology Company Co.Ltd.,Beijing 100013,China 2012International Journal of Mining Science and Technology2012,22,5:13
11Numerical simulation and experimental verification of bubble size distribution in an air dense medium fluidized bed显示文摘Bubble size distribution is the basic apparent performance and obvious characteristics in the air dense medium fluidized bed (ADMFB). The approaches of numerical simulation and experimental verification were combined to conduct the further research on the bubble generation and movement behavior. The results show that ADMFB could display favorable expanded characteristics after steady fluidization. With different particle size distributions of magnetite powder as medium solids, we selected an appropriate prediction model for the mean bubble diameter in ADMFB. The comparison results indicate that the mean bubble diameters along the bed heights are 35 mm < D b < 66 mm and 40 mm < D b < 69 mm with the magnetite powder of 0.3 mm+0.15mm and 0.15mm+0.074mm, respectively. The prediction model provides good agreements with the experimental and simulation data. Based on the optimal operating gas velocity distribution, the mixture of magnetite powder and <1mm fine coal as medium solids were utilized to carry out the separation experiment on 6-50mm raw coal. The results show that an optimal separation density d P of 1.73g/cm 3 with a probable error E of 0.07g/cm 3 and a recovery efficiency of 99.97% is achieved, which indicates good separation performance by applying ADMFB.He Jingfeng Zhao Yuemin Luo Zhenfu He Yaqun Duan Chenlong 2013International Journal of Mining Science and Technology2013,23,3:11
12New progress in the processing and efficient utilization of coal显示文摘Coal accounts for about 70% of the primary energy sources in China.The environmental pollution and resources waste involved with coal processing and utilization are serious.It is therefore urgent to develop highly-efficient coal resources utilization theory and methods with low-carbon discharge.Based on our long-term basic research and technology development,the progress in beneficiation,cleaning,and transformation of coal,which includes dense phase fluidized bed dry beneficiation,deep screening of wet fine coal,micro-bubble fiotation column separation,molecular coal chemistry,and transformation and separation of coal and its derivatives into value-added chemicals under mild conditions,is discussed.Zhao Yuemin Liu Jiongtian wei xianyong Luo Zhenfu Chen Qingru Song Shulei 2011Mining Science and Technology2011,21,4:9
13Amended Kalman Filter for Maneuvering Target Tracking显示文摘The conventional Kalman filter(KF) which uses the current measurement to estimate the current state is a posterior estimation. KF is identified as the optimal estimation in linear models with Gaussian noise. However,the performance of KF with incomplete information may be degraded or diverged. In order to improve the performance of KF, an Amended KF(AKF) is proposed by using more posterior measurements. The principle, derivation and recursive process of AKF are presented. The differences among Kalman smoother, adaptive fading method and AKF are analyzed. The simulation results of target tracking with different covariance of motion model indicate the high precision and robustness of AKF.YANG Yongjian FAN Xiaoguang ZHUO Zhenfu WANG Shengda NAN Jianguo XU Yunshan 2016Chinese Journal of Electronics2016,25,6:9
14Designing efficient proxy signature schemes for mobile communication显示文摘Proxy signature is an active cryptographic research area,and a wide range of litera- tures can be found nowadays suggesting improvement and generalization of existing protocols in various directions.However,from the efficiency view,many proposed proxy signature schemes in these literatures are not satisfying and cannot fit to the mobile communication.Therefore,there is a desire to design efficient proxy sig- nature schemes.Based on Boneh et al's pairing-based short signature,this paper presents two proxy signature schemes.One is proxy-protected signature scheme, and the other is proxy aggregate signature scheme.Since both of them can achieve high efficiency,it is believed that they are specially suitable for mobile communica- tion environment.LU RongXing DONG XiaoLei CAO ZhenFu 2008Science in China(Series F)2008,51,2:9
15Perfect forward secure identity-based authenticated key agreement protocol in the escrow mode显示文摘The majority of existing escrowable identity-based key agreement protocols only provide partial forward secrecy. Such protocols are, arguably, not suitable for many real-word applications, as the latter tends to require a stronger sense of forward secrecy—perfect forward secrecy. In this paper, we propose an efficient perfect forward-secure identity-based key agreement protocol in the escrow mode. We prove the security of our protocol in the random oracle model, assuming the intractability of the Gap Bilinear Diffie-Hellman (GBDH) problem.WANG ShengBao CAO ZhenFu CHENG ZhaoHui CHOO Kim-Kwang Raymond 2009Science in China(Series F)2009,52,8:9
16Flotation technology of refractory low-grade molybdenum ore显示文摘Because of the low grade, high oxidation rate and the accumulation of little associated metal sulfide ore in the molybdenum concentrate during flotation, the Qingyang molybdenum ore is difficult to beneficiate. The experimental studies of grinding fineness, the amount of roughing modifier, depressant and collector were completed. In the cleaning process, the contrast experiments of one regrinding, the regrinding and scrubbing, two-stage regrinding was carried. The result shows that the grade of molybdenum ore concentrate is 45.31%, the recovery is 65.98% and the rich ore ratio reaches 20.59% by the regrinding and scrubbing seven cleaning, the regrinding of concentrations from middling of molybdenum-sulfur separation. The regularly-concentrated material from the apparatus was as the middling products. Hence, ideal beneficiation index can be obtained with a rational mineral processing, which offers new beneficiating technology for the refractory low-grade molybdenum ore in China.Du Shuhua Luo Zhenfu 2013International Journal of Mining Science and Technology2013,23,2:9
17Identity-based signature scheme based on quadratic residues显示文摘Identity-based(ID-based)cryptography has drawn great concerns in recent years,and most of ID-based schemes are constructed from bilinear parings.Therefore,ID-based scheme without pairing is of great interest in the field of cryptography.Up to now, there still remains a challenge to construct ID-based signature scheme from quadratic residues.Thus,we aim to meet this challenge by proposing a concrete scheme.In this paper,we first introduce the technique of how to calculate a 2lth root of a quadratic residue,and then give a concrete ID-based signature scheme using such technique. We also prove that our scheme is chosen message and ID secure in the random oracle model,assuming the hardness of factoring.CHAI ZhenChuan CAO ZhenFu DONG XiaoLei 2007Science in China(Series F)2007,50,3:7
18Effect of a starch-based filter aid on the dewatering of fine clean coal显示文摘The dewatering of fine, flotation cleaned coals from Huaibei and Xuzhou (bituminous) and Yongcheng (anthracite) were studied. The supernatant and filter cake were examined to determine the rate and extent of flocculation and dewatering. A starch-based filter aid was used to increase flocculation and dewatering rates. The filtration constant, K, and compression index, s, of the Yongcheng slurry were measured under various conditions. A designed experiment was performed to determine optimum conditions for dewatering. The results showed that the filter aid enhanced flocculation and coagulation of the fine cleaned coal slurry, enhanced the structure of the filter cake and promoted dewatering of the cake. Moisture content in the cake was reduced to 17% after vacuum filtration.GONG Guanqun XIE Guangyuan ZHANG Yingjie WANG Ziliang WANG Jin XIE Linghui LUO Zhenfu 2010Mining Science and Technology2010,20,4:6
19THRESHOLD PROXY RE-SIGNATURE显示文摘纸是设计探讨半的一个有效、安全的答案的这的焦点在代理重新签名计划信任了问题,即,代理从用户 A 知道重新签名钥匙到用户 B ,他因此能翻译用户 A 做到用户 B 的任何签名,它损坏代理重新签名计划的必要要求(非否认性质)。在这份报纸,作者首先为阀值代理重新签名计划定义安全模型,然后基于 Ateniese-Hohenbergers 和 Shao-Cao-Wang-Liangs 途径建议二个阀值代理重新签名计划。Piyi YANG Zhenfu CAO Xiaolei DONG 2011Journal of Systems Science & Complexity2011,24,4:6
20Provably secure robust threshold partial blind signature显示文摘Threshold digital signature and blind signature are playing important roles in cryptography as well as in practical applications such as e-cash and e-voting systems. Over the past few years, many cryptographic researchers have made considerable headway in this field. However, to our knowledge, most of existing threshold blind signature schemes are based on the discrete logarithm problem. In this paper, we propose a new robust threshold partial blind signature scheme based on improved RSA cryptosystem. This scheme is the first threshold partial blind signature scheme based on factoring, and the robustness of threshold partial blind signature is also introduced. Moreover, in practical application, the proposed scheme will be especially suitable for blind signature-based voting systems with multiple administrators and secure electronic cash systems to prevent their abuse.CAO Zhenfu ZHU Haojin LU Rongxing 2006Science in China(Series F)2006,49,5:5
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