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| 1 | BpMADS12 gene role in lignin biosynthesis of Betula platyphylla Suk by transcriptome analysis显示文摘MADS-box transcription factors show highly diverse regulatory functions in a wide variety of organisms.In this study,we characterized a MADS-box gene(BpMADS12) from the white birch(Betula platyphylla Suk).This gene is a member of the suppressor of overexpression of CO 1/tomato MADS 3 class of MADS-box genes.We generated lines overexpressing BpMADS12 and found that these had higher levels of lignin compared to that observed in nontransgenic lines.Transcriptome analysis revealed numerous changes in gene expression patterns.In total,8794 differentially expressed genes were identified,including 5006 upregulated unigenes and 3788 downregulated unigenes in Bp MADS-overexpression lines.Differentially expressed genes involved in the pathways for lignin and brassinosteroid biosynthesis were significantly enriched and may have contributed to phenotypic changes.The results from a quantitative RT-PCR analysis were consistent those obtained with the transcriptome analysis.Our transcriptome analysis,in combination with measurement of lignin level,indicated that Bp MADS12 promotes lignin synthesis through regulation of key enzymes in response to brassinosteroid signaling.These results suggest that this MADS-box protein is crucial to all subsequent structural events and provide a good foundation for studies aiming to elucidate the developmental mechanisms underlying formation of wood. | Huiyu Li Yang Yang Zijia Wang Xiaohong Guo Feifei Liu Jing Jiang Guifeng Liu | 2016 | Journal of Forestry Research2016，27，5： | 4 |
| 2 | Involvement of long non-coding RNAs in the progression of esophageal cancer显示文摘Esophageal cancer(EC)is one of the most common malignant tumors of the digestive system with high incidence and mortality rate worldwide.Therefore,exploring the pathogenesis of ECand searching for new targeted therapies are the current research hotspot for EC treatment.Long non-coding RNAs(lncRNAs)are endogenous RNAs with more than 200 nucleotides,but without proteincoding function.In recent years,lncRNAs have gradually become the focuses in the field of non-coding RNA.Some lncRNAs have been proved to be closely related to the pathogenesis of EC.Many lncRNAs are abnormally expressed in EC and participate in many biological processes including cell proliferation,apoptosis,and metastasis by inhibiting or promoting target gene expression.LncRNAs can also regulate the progression of EC through epithelial-mesenchymal transformation(EMT),which is closely related to the occurrence,development,and prognosis of EC.In this article,we review and discuss the involvement of lncRNAs in the progression of EC. | Wenhua Xue Yuanyuan Zheng Zhibo Shen Lifeng Li Zhirui Fan Wenbin Wang Zijia Zhu Yunkai Zhai Jie Zhao Quancheng Kan | 2021 | Cancer Communications2021，41，5： | 4 |
| 3 | Screening high-quality fetal bovine serum for porcine oocyte maturation in vitro显示文摘Fetal bovine serum(FBS) is widely used in cell cultures due to its high stability and easy access. It was also used as a substitute for porcine follicular fluid(PFF) in previous studies. However, FBS components are unclear, and the presence of FBS in culture media may introduce a variation from batch to batch. This study aimed to establish an effective method to screen FBS in place of PFF in the culture media for porcine oocytes in vitro. We screened FBS from different sources by using porcine fetal fibroblast cells. The effects of six FBS samples on porcine fetal fibroblast cell growth were tested via frozen cell survival assay, cell clone formation assay, cell growth curve, and cell passage activity assay. The best serum that we called GFBS(heat-inactivated FBS, cat. no. 10500-64;Gibco) showed a similar effect on the maturation and development of porcine oocytes to that of PFF and can be used as a good substitute for PFF. These results suggested that the porcine fetal fibroblast cell culture test can be used as a valuable method to screen FBS for porcine oocyte maturation and embryonic development in vitro. | Xueqing Liu Qiaoli Lang Meng Wu Xiaoyan You Qiling He Ling Luo Zijia Liu Puying Xiao Nan Huang Xi Yang Liangpeng Ge | 2019 | Animal Models and Experimental Medicine2019，2，4： | 3 |
| 4 | Rational structure design to realize high-performance SiOx@C anode material for lithium ion batteries显示文摘Silicon suboxide(SiOx)is considered to be one of the most promising materials for next-generation anode due to its high energy density.For its preparation,the wet-chemistry method is a cost-effective and readily scalable route,while the so-derived SiOx usually shows lower capacity compared with that prepared by high temperature-vacuum evaporation route.Herein,we present an elaborate particle structure design to realize the wet-chemistry preparation of a high-performance SiOx/C nanocomposite.Dandelion-like highly porous SiOx particle coated with conformal carbon layer is designed and prepared.The highly-porous SiOx skeleton provides plenty specific surface for intimate contact with carbon layer to allow a deep reduction of SiOx to a low O/Si ratio at relatively low temperature(700℃),enabling a high specific capacity.The abundant mesoscale voids effectively accommodate the volume variation of SiOx skeleton,ensuring the high structural stability of SiOx@C during lithiation/delithiation process.Meanwhile,the three-dimensional(3D)conformal carbon layer provides a fast electron/ion transportation,allowing an enhanced electrodereaction kinetics.Owing to the optimized O/Si ratio and well-engineered structure,the prepared SiOx@C electrode delivers an ultra-high capacity(1,115.8 mAh·g^-1 at 0.1 A·g^-1 after 200 cycles)and ultra-long lifespan(635 mAh·g^-1 at 2 A·g^-l after 1,000 cycles).To the best of our knowledge,the achieved combination of ultra-high specific capacity and ultra-long cycling life is unprecedented. | Zhaolin Li Hailei Zhao Jie Wang Tianhou Zhang Boyang Fu Zijia Zhang Xin Tao | 2020 | Nano Research2020，13，2： | 3 |
| 5 | Surface clogging process modeling of suspended solids during urban stormwater aquifer recharge显示文摘Aquifer recharge,which uses urban stormwater,is an effective technique to control the negative effects of groundwater overexploitation,while clogging problems in infiltration systems remain the key restricting factor in broadening its practice.Quantitative understanding of the clogging process is still very poor.A laboratory study was conducted to understand surface physical clogging processes,with the primary aim of developing a model for predicting suspended solid clogging processes before aquifer recharge projects start.The experiments investigated the clogging characteristics of different suspended solid sizes in recharge water by using a series of one-dimensional fine quartz sand columns.The results showed that the smaller the suspended particles in recharge water,the farther the distance of movement and the larger the scope of clogging in porous media.Clogging extents in fine sand were 1 cm,for suspended particle size ranging from 0.075 to 0.0385 mm,and 2 cm,for particles less than 0.0385 mm.In addition,clogging development occurred more rapidly for smaller suspended solid particles.It took 48,42,and 36 hr respectively,for large-,medium-,and small-sized particles to reach pre-determined clogging standards.An empirical formula and iteration model for the surface clogging evolution process were derived.The verification results obtained from stormwater recharge into fine sand demonstrated that the model could reflect the real laws of the surface clogging process. | Zijia Wang Xinqiang Du Yuesuo Yang Xueyan Ye | 2012 | Journal of Environmental Sciences2012，24，8： | 2 |
| 6 | Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants显示文摘SARS-CoV-2(severe acute respiratory syndrome coronavirus 2)has evolved many variants with stronger infectivity and immune evasion than the original strain,including Alpha,Beta,Gamma,Delta,Epsilon,Kappa,lota,Lambda,and 21H strains.Amino acid mutations are enriched in the spike protein of SARS CoV-2.which plays a crucial role in cell infetion.However,the impact of these mutations on protein structure and function is unclear.Understanding the pathophysiology and pandemic feaures of these SARS-CoV-2 variants requires knowledge of the spike protein structures.Here,we obtained the spike protein structures of 10 main globally endemic SARS CoV-2 strains using AlphaFold2.The clustering analysis based on structural similarity revealed the unique features of the mainly pandemic SARS CoV-2 Delta variants.indicating that structural clusters can reflect the current characteristics of the epidemic more accurately than those based on the protein sequence.The analysis of the binding afinities of ACE2-RBD,antibody-NTD,and antibody-RBD complexes in the different variants revealed that the recognition of antibodies against SI NTD and RBD was decreased in the variants,especally the Delta variant compared with the original strain,which may induce the immune evasion of SARS-CoV-2 variants.Furthermore,by virtual screening the ZINC database against a high-accuracy predicted structure of Delta spike protein and experimental validation,we identified multiple compounds that target S1 NTD and RBD,which might contribute towards the development of clinical anti-SARS-CoV-2 medicines.Our findings provided a basic foundation for future in vitro and in vivo investigations that might speed up the development of potential therapies for the SARS-CoV-2 va riants. | Qiangzhen Yang Xuemin Jian Ali Alamdar Shah Syed Aamir Fahira Chenxiang Zheng zijia Zhu Ke Wang Jinmai Zhang Yangin Wen Zhiqiang Li Dun Pan Tingting Lu Zhuo Wang Yongyong Shi | 2022 | Research2022，，2： | 2 |
| 7 | 查看详情显示文摘 | Yu Zijia Zhang Xianfa Yang Guiling | | 0，，24： | 1 |
| 8 | Extenics-Based Evaluation of China's Insurance Ecological Environment 显示文摘 | Deng Qingbiao Pu Zijia | 2011 | Energy Procedia2011，5，3： | 1 |
| 9 | Alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC-bioautographic assay显示文摘 | Zheng Xiyuan Zhang Zijia Chou Guixin | 2009 | Arch Pharm Res2009，32，9： | 1 |
| 10 | Antioxidant phenolic compounds from walnut kernels ( Juglans regia L.)显示文摘 | Zijia Zhang Liping Liao Jeffrey Moore Tao Wu Zhengtao Wang | 2008 | Food Chemistry2008，，1： | 1 |
| 11 | Effects of excessive nitrogen fertilizer and soil moisture deficiency on antioxidant enzyme system and osmotic adjustment in tomato seedlings显示文摘Long-term excessive application of nitrogen fertilizer induces secondary salinization of soil,which results in inhibiting plant growth.In addition,soil moisture deficiency also affects plant growth.To investigate the effects of excessive nitrogen fertilizer and soil moisture deficiency on the antioxidant enzyme system,plant water relations analyzed through pressure-volume(P-V)curve,and photosynthetic light response parameters in tomato(Solanum lycopersicum L.Myoko)seedlings,an indoor experiment of about 50 d was conducted using two irrigation water amounts based on field capacity(soil moisture deficiency:50%-80%;adequate water:70%-80%),two nitrogen fertilizer rates(moderate nitrogen;excessive nitrogen fertilizer:0.585 g/pot)and two types of irrigation water(tap water and microbial diluent).The results showed that excessive nitrogen fertilizer(N)and soil moisture deficiency(W)reduced the biomass of tomato seedlings.In comparison to CK(combination of adequate water and tap water quality),microbial dilution(EM)increased plant biomass by 5.2%.Also,the nitrogen application increased chlorophyll relative contents(SPAD).The maximum net photosynthetic rate(Pc)decreased with nitrogen application and increased with EM application and irrigation amount.Excessive nitrogen application increased the plant nitrate reductase activity(NR).The plant NR in the N treatment showed a 13.0%increase compared to CK,and the plant NR in the treatment of nitrogen application with water deficiency(WN)increased 34.0%compared to water deficiency(W).After applying excessive nitrogen,N,EM-N,WN,EM-WN respectively increased the plant nitrate reductase activity by 13.0%,22.9%,34.0%,and 28.6%,compared with the corresponding treatment with moderate nitrogen(i.e.,CK,EM,W and EM-W).In addition,the activities of antioxidant enzymes[superoxide dismutase(SOD),peroxidase(POD)and catalase(CAT)]in four treatments of nitrogen application(N,EM-N,WN,EM-WN)also increased significantly.Both soil moisture and nitrogen fertilizer significantly affect the parameters of osmotic adjustment,which is manifested in the reduction of osmotic potential(π_(FT)),and the increase in the osmotic concentration(C_(osm))and concentration difference(ΔC_(osm)).But the decrease in the relative water content of apoplast(ζ_(ap))indicated that water deficiency and excessive nitrogen reduced the water absorption and water retention capacity of tomatoes to a certain extent.In conclusion,excessive nitrogen application and soil moisture deficiency inhibit plant growth significantly in this experiment.Meanwhile,microbial dilution can alleviate excessive nitrogen fertilizer and water stress to some extent,but the effect was not significant. | Yujie Zhang Shuangen Yu Zijia Li Tingting Chang Qicong Xu Huilian Xu Jie Zhang | 2022 | International Journal of Agricultural and Biological Engineering2022，15，2： | 1 |
| 12 | Antioxidant phenolic compounds from walnut kernels (Juglansregia L)显示文摘 | ZHANG ZIJIA LIAO LIPING MOORE JEFFRE | 2009 | Food Chemistry2009，113，1： | 1 |
| 13 | Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay显示文摘 | Guodong Xiao Guowen Li Liang Chen Zijia Zhang Jun-Jie Yin Tao Wu Zhihong Cheng Xiaohui Wei Zhengtao Wang | 2010 | Journal of Chromatography A2010，，34： | 1 |
| 14 | Endogenous Security-Aware Resource Management for Digital Twin and 6G Edge Intelligence Integrated Smart Park显示文摘The integration of digital twin(DT)and 6G edge intelligence provides accurate forecasting for distributed resources control in smart park.However,the adverse impact of model poisoning attacks on DT model training cannot be ignored.To address this issue,we firstly construct the models of DT model training and model poisoning attacks.An optimization problem is formulated to minimize the weighted sum of the DT loss function and DT model training delay.Then,the problem is transformed and solved by the proposed Multi-timescAle endogenouS securiTy-aware DQN-based rEsouRce management algorithm(MASTER)based on DT-assisted state information evaluation and attack detection.MASTER adopts multi-timescale deep Q-learning(DQN)networks to jointly schedule local training epochs and devices.It actively adjusts resource management strategies based on estimated attack probability to achieve endogenous security awareness.Simulation results demonstrate that MASTER has excellent performances in DT model training accuracy and delay. | Sunxuan Zhang Zijia Yao Haijun Liao Zhenyu Zhou Yilong Chen Zhaoyang You | 2023 | China Communications2023，20，2： | 0 |
| 15 | Vitreous Humor:A Review of Biochemical Constituents in Postmortem Interval Estimation显示文摘Postmortem changes in the biochemical constituents of the vitreous humor have been widely used to estimate the postmortem interval(PMI)over the past several decades.However,few reviews have summarized the relationship between the postmortem vitreous biochemical constituents and time of death.Herein,the relationship between PMI and single biochemical components,including vitreous potassium,hypoxanthine,and amino acids,as well as comparisons of each statistical parameter in the formula,is summarized.We also discuss other compounds such as urea and uric acid,which have no direct relationship with PMI.Utility of multiple constituent simultaneous analysis for estimating PMI is being increasingly investigated.The promising idea of using simultaneous analysis of multiple constituents to determine PMI is proposed as a future research direction. | Weichen Li Yunfeng Chang Zijia Cheng Jiang Ling Leiming Han Xingmei Li Yanjun Ding | 2018 | Journal of Forensic Science and Medicine2018，4，2： | 0 |
| 16 | Theoretical investigation on self-recovery regulation method for diesel engine misalignment through co-simulation显示文摘Misalignment is one of the most common faults for the diesel engine.In order to eliminate the misalignment fault of the diesel engine in the process of operation,a targeting self-recovery regulation system is constructed by using a movable base and displacement sensors.Misalignment is monitored and detected in real time,the value of misalignment is calculated rapidly and accurately,andintelligent decision is made.Then,the base is moved reversely with a definite target to drive the shaft to translate or rotate,so that the shafts can be recovered to alignment online.A co-simulation model for the self-recovery system is established which consists of a dynamic model of the crankshaft system and control model.The self-recovery regulation process of misalignment is simulated.The simulation results show that the system can accurately calculate the misalignment values,with an error of less than 5%,and can automatically eliminate the misalignment fault of the diesel engine online.The research results provide theoretical support for the self-recovery regulation of misalignment fault,and due to the universality of structure and principle,the self-recovery system is not only suitable for diesel engine,but also for other rotating machineries. | 江志农 Wang Zijia Mao Zhiwei Zhang Jinjie Wang Chenguang Huang Yifei | 2021 | High Technology Letters2021，27，3： | 0 |
| 17 | Research on full-period acquisition method for diesel engine based on self-adaptive correlation analysis显示文摘Full-period signal acquisition of vibration signal plays a vital role in the health monitoring and fault diagnosis of modern industrial equipment group. The traditional full-period signal acquisition methods usually need not only a reference signal generated from special key phase device but also a reserved position, which is only suitable for a small number of particular equipment. A novel full-period signal acquisition method without key phase is proposed to construct the time-frequency method with strong energy concentration called the synchrosqueezing generalized S-Transform(SGST), combining together the Teager energy operator(TEO) and self-adaptive correlation analysis(SACA) based on the vibration signals of both gear and cylinder head. Actual vibration signals of diesel engine are employed to verify the feasibility and effectiveness of the proposed method by comparing with traditional method with special key phase device. By comparisons, the results show that full-period signal acquisition method without key phase has approximate accuracy for diesel engine under different working conditions. | 赵海朋 Mao Zhiwei Zhang Jinjie Lai Yuehua Wang Zijia Jiang Zhinong | 2020 | High Technology Letters2020，26，3： | 0 |
| 18 | Towards extreme fast charging of 4.6 V LiCoO_(2) via mitigating high-voltage kinetic hindrance显示文摘High-voltage LiCoO_(2)(LCO) is an attractive cathode for ultra-high energy density lithium-ion batteries(LIBs) in the 3 C markets.However,the sluggish lithium-ion diffusion at high voltage significantly hampers its rate capability.Herein,combining experiments with density functional theory(DFT) calculations,we demonstrate that the kinetic limitations can be mitigated by a facial Mg^(2+)+Gd^(3+)co-doping method.The as-prepared LCO shows significantly enhanced Li-ion diffusion mobility at high voltage,making more homogenous Li-ion de/intercalation at a high-rate charge/discharge process.The homogeneity enables the structural stability of LCO at a high-rate current density,inhibiting stress accumulation and irreversible phase transition.When used in combination with a Li metal anode,the doped LCO shows an extreme fast charging(XFC) capability,with a superior high capacity of 193.1 mAh g^(-1)even at the current density of 20 C and high-rate capacity retention of 91.3% after 100 cycles at 5 C.This work provides a new insight to prepare XFC high-voltage LCO cathode materials. | Yu Tang Jun Zhao He Zhu Jincan Ren Wei Wang Yongjin Fang Zhiyong Huang Zijia Yin Yalan Huang Binghao Zhang Tingting Yang Tianyi Li Leighanne CGallington Si Lan Yang Ren Qi Liu | 2023 | Journal of Energy Chemistry2023，，3： | 0 |
| 19 | Scalable and Robust Bio-inspired Organogel Coating by Spraying Method Towards Dynamic Anti-scaling显示文摘Scaling usually causes serious problems in daily life and industrial production.Currently,developing passive anti-scaling coatings has shown promises to overcome this problem.In this work,we fabricated a scalable and robust bio-inspired organogel(BIO)coating,showing dynamic scale resistance in the oil/brine mixture.The oil layer of the BIO coating was utilized as a barrier to inhibit scale nucleation and reduce scale adhesion.The mechanical strength of the coating was optimized by regulating nanoparticle contents.Moreover,the universality of scale resistance was demonstrated by varying the types of nanoparticles,oils and scales.Compared with commercial pipeline materials,such as copper,this BIO coating significantly reduces scale deposition after 240-h scaling test(ca.93%reduction).Therefore,this study designs scalable and robust organogel coatings for sustainable scale resistance,which may be used for practical application in oil production. | ZANG Ruhua CHEN Zijia YANG Hui WANG Yixuan WANG Shutao MENG Jingxin | 2023 | Chemical Research in Chinese Universities2023，39，1： | 0 |
| 20 | Disturbance-level-dependent post-disturbance succession in a Eurasian steppe显示文摘Anthropogenic disturbances may decrease as we take measures to control them.However,the patterns and mechanisms of postdisturbance ecosystem succession have rarely been studied.Here we reported that disturbance level determined the importance of stochastic relative to deterministic changes in ecosystem components(plant community composition,soil microbial community composition,and soil physicochemical indices),and thus predefined the pattern of post-disturbance ecosystem succession.We proposed a theoretical framework with five disturbance levels corresponding to distinct succession patterns.We conducted a nitrogen addition experiment in a temperate steppe,monitored these ecosystem components during'disturbance'treatment(2010-2014)and post-treatment'succession'(2014-2018).The disturbance level experienced by each component in each treatment was inferred by fitting the observed succession patterns into the theoretical framework.The mean disturbance level of these components was found to increase quadratically with nitrogen addition rate.This was because increasing nitrogen addition reduced the importance of stochastic relative to deterministic changes in these components,and these changes had a quadratic relationship with disturbance level.Overall,our results suggested that by monitoring the importance of stochastic relative to deterministic changes in an ecosystem,we can estimate disturbance levels and predict succession patterns,as well as propose disturbance-level-dependent strategies for post-disturbance restoration. | Junjie Yang Minjie Xu Shuang Pang Lili Gao Zijia Zhang Zhiping Wang Yunhai Zhang Xingguo Han Ximei Zhang | 2022 | Science China(Life Sciences)2022，65，1： | 0 |
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