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| 1 | Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing显示文摘COVID-19,caused by SARS-CoV-2[1,2],has been contained in China through stringent non-pharmaceutical interventions.Border control and quarantine have effectively prevented the virus from being spread by infected travellers,but the risk of resurgence caused by other routes of introduction and transmission remains unclear,and current strategies to prevent resurgence could be flawed.Since July,SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China[3,4].However,there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission.Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing. | Xinghuo Pang Lili Ren Shuangsheng Wu Wentai Ma Jian Yang Lin Di Jie Li Yan Xiao Lu Kang Shichang Du Jing Du Jing Wang Gang Li Shuguang Zhai Lijuan Chen Wenxiong Zhou Shengjie Lai Lei Gao Yang Pan Quanyi Wang Mingkun Li Jianbin Wang Yanyi Huang Jianwei Wang COVID-19 Field Response Group COVID-19 Laboratory Testing Group | 2020 | National Science Review2020，7，12： | 51 |
| 2 | Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic显示文摘Findings:We identified 5683 unique data sources,of which 48 met inclusion criteria(46 studies met criteria for major depressive disorder and 27 for anxiety disorders).Two COVID-19 impact indicators,specifically daily SARS-CoV-2 infection rates and reductions in human mobility,were associated with increased prevalence of major depressive disorder(regression coefficient[B]0-9[95%uncertainty interval 0-1 to 1-8;p=0-029]for human mobility。 | 无 | 2021 | 四川生理科学杂志2021，43，8： | 14 |
| 3 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 4 | Serum IgA,IgM,and IgG responses in COVID-19显示文摘Currently,detecting SARS-CoV-2 RNAs is a standard approach for COVID-19 diagnosis.However,there is an urgent need for reliable and rapid serological diagnostic methods to screen SARS-CoV-2-infected people including those who do not have overt symptoms.Most emerging studies described serological tests based on detection of SARS-CoV-2-specific IgM and IgG.1–4 Although detection of SARS-CoV-2-specific IgA in serum has been reported in few papers,5,6 analyses of IgA levels in a larger number of COVID-19 patients are still lacking. | Huan Ma Weihong Zeng Hongliang He Dan Zhao Dehua Jiang Peigen Zhou Linzhao Cheng Yajuan Li Xiaoling Ma Tengchuan Jin | 2020 | Cellular & Molecular Immunology2020，17，7： | 12 |
| 5 | Azvudine(FNC):a promising clinical candidate for COVID-19 treatment显示文摘A very recent work published in Advanced Science by our group reveals that 2′-deoxy-2′-β-fluoro-4′-azidocytidine(Azvudine,FNC),a clinical candidate originally developed for HIV treatment,has entered clinical trial in China for evaluating its efficacy and safety(ChiCTR2000029853),showing promise for treating novel coronavirus disease 2019(COVID-19).1 This work suggests that nucleoside-based antivirus agents could be repurposed for COVID-19 treatment. | Bin Yu Junbiao Chang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 9 |
| 6 | 无/低代码软件开发的兴起——无需经验?显示文摘纽约市的官员想要追踪新冠病毒肺炎(COVID-19)在城市中肆虐的情况,并有效地为有需要的人提供服务。为此,他们建立了一个在线门户网站,用于收集COVID-19感染者以及病例接触者的信息。速度至关重要,COVID-19门户网站三天后便上线运行了,而这一切都无需编写任何代码[1]。这一壮举由纽约市的初创公司Unqork所开发的无代码(no-code)软件开发平台实现。 | Marcus Woo | 2020 | Engineering2020，6，9： | 8 |
| 7 | A cohort autopsy study defines COVID-19 systemic pathogenesis显示文摘Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by dysfunction of the lungs and extrapulmonary organs.However,the organotropism of SARS-CoV-2 and the port of virus entry for systemic dissemination remain largely unknown.We profiled 26 COVID-19 autopsy cases from four cohorts in Wuhan,China,and determined the systemic distribution of SARS-CoV-2. | Xiao-Hong Yao Tao Luo Yu Shi Zhi-Cheng He Rui Tang Pei-Pei Zhang Jun Cai Xiang-Dong Zhou Dong-Po Jiang Xiao-Chun Fei Xue-Quan Huang Lei Zhao Heng Zhang Hai-Bo Wu Yong Ren Zhen-Hua Liu Hua-Rong Zhang Cong Chen Wen-Juan Fu Heng Li Xin-Yi Xia Rong Chen Yan Wang Xin-Dong Liu Chang-Lin Yin Ze-Xuan Yan Juan Wang Rui Jing Tai-Sheng Li Wei-Qin Li Chao-Fu Wang Yan-Qing Ding Qing Mao Ding-Yu Zhang Shu-Yang Zhang Yi-Fang Ping Xiu-Wu Bian | 2021 | Cell Research2021，31，8： | 7 |
| 8 | Two Reemergent Cases of COVID-19—Hebei Province,China,January 2,2021显示文摘On January 2,2021,2 cases of coronavirus disease 2019(COVID-19)were identified in 2 cities of Hebei Province,and genomic sequencing suggested that the cases likely resulted from the same origin.The first case(Patient A)was identified as positive at 12∶18 in Shijiazhuang City,the capital of Hebei Province,and the second case(Patient B)was identified as positive at 21∶00 in Xingtai City. | Shunxiang Qi Xiang Zhao Peter Hao Nankun Liu George F.Gao Yang Song Wenbo Xu Qi Li | 2021 | China CDC weekly2021，3，2： | 7 |
| 9 | 江苏省儿童新型冠状病毒感染诊疗方案专家建议(试行第一版)显示文摘2019年12月以来,湖北省武汉市陆续发现了多例2019新型冠状病毒(2019 novel coronavirus,2019-nCoV)[即严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronarivus 2,SARSCoV-2)]感染的肺炎患者,随着疫情的蔓延,我国其他地区也相继发现了此类病例。该病作为急性呼吸道传染病已纳入《中华人民共和国传染病防治法》规定的乙类传染病,按甲类传染病管理。随着疫情进入高峰阶段和病原学检测工作的开展,儿童感染报告病例逐渐增多,且出现有新生儿感染病例的报道。 | 无 甘卫华 缪红军 赵德育 吴明赴 陆超 王军 田曼 李莺 骆培良 顾健辉 袁斌 汪受传 赵霞 | 2020 | 南京医科大学学报(自然科学版)2020，40，3： | 7 |
| 10 | COVID-19 Mortality and Vaccine Coverage——Hong Kong Special Administrative Region,China,January 6,2022-March 21,2022显示文摘Summary What is already known about this topic?COVID-19 vaccines are important tools to protect populations from severe disease and death.What is added by this report?Among persons aged≥60 years in Hong Kong,49%,had received≥2 doses of a COVID-19 vaccine,and vaccination coverage declined with age.During January-March 2022,reported COVID-19-associated deaths rose rapidly in Hong Kong.Among these deaths,96%occurred in persons aged≥60 years;within this age group,the risk for death was 20 times lower among those who were fully vaccinated compared with those who were unvaccinated. | Dallas J.Smith Avi J.Hakim Gabriel M.Leung Wenbo Xu WWilliam Schluter Ryan T.Novak Barbara Marston Bradley S.Hersh | 2022 | China CDC weekly2022，4，14： | 6 |
| 11 | Three Cases of COVID-19 Variant Delta With and Without Vaccination——Chengdu City,Sichuan Province,April-May,2021显示文摘On April 26,2021,a 33-year-old male Chinese sailor returning from India via Kathmandu,Nepal,tested positive for the coronavirus disease 2019(COVID-19)by Chengdu Customs and was confirmed positive by Chengdu CDC(Case A).On May 2,2021,a housewife in the same flight tested positive for COVID-19 by Pengzhou CDC in Sichuan Province during her quarantine period and was confirmed positive by Chengdu CDC the next day(Case B). | Heng Chen Yi Mao Zhenhua Duan Liang Wang Yue Cheng Yingxue Dai Haixia Luo Wenjun Xie Shuangfeng Fan Yuzhen Zhou Jingpei Xu Lan Feng Liwen Hu Zhu Liu Xian Liang Liangshuang Jiang Xiaoli Tuo | 2021 | China CDC weekly2021，3，25： | 5 |
| 12 | 美国FDA紧急批准硫酸羟氯喹和磷酸氯喹用于治疗COVID-19显示文摘2020年3月28日,美国食品药品监督管理局(FDA)紧急批准(Emergency Use Authorization,EUA)医院使用硫酸羟氯喹(hydroxychloroquine sulfate)和磷酸氯喹(chloroquine phosphate)对已入院的青少年及成年COVID-19患者进行治疗。这两种药物(来源于社会捐赠)将由美国应急药品国家战略储备局(SNS,Strategic National Stockpile)与美国联邦紧急管理局(Federal Emergency Management Agency,FEMA)合作分配至各州,再由各州的卫生部门根据实际需要发放给医务人员。 | 夏训明(编译) | 2020 | 广东药科大学学报2020，36，2： | 5 |
| 13 | A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice显示文摘Dear Editor,Since the beginning of this century,humanity has been struck three times by the coronavirus outbreak.The most recent one is caused by the SARS-CoV-2 virus,which was first reported in January 2020 and spread rapidly worldwide,developing into a global coronavirus disease pandemic coded COVID-19.1 By July 28,2020,SARS-CoV-2 has caused over sixteen million COVID-19 cases worldwide and 650,805 deaths.2 Such a grave situation has made the development of a COVID-19 vaccine imperative and urgent. | Jing Lu Guoliang Lu Shudan Tan Jia Xia Hualong Xiong Xiaofei Yu Qingqing Qi Xiang Yu Li Li Hang Yu Ningshao Xia Tianying Zhang Yingjie Xu Jinzhong Lin | 2020 | Cell Research2020，30，10： | 5 |
| 14 | Comparison of nonhuman primates identified the suitable model for COVID-19显示文摘Identification of a suitable nonhuman primate(NHP)model of COVID-19 remains challenging.Here,we characterized severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in three NHP species:Old World monkeys Macaca mulatta(M.mulatta)and Macaca fascicularis(M.fascicularis)and New World monkey Callithrix jacchus(C.jacchus).Infected M.mulatta and M.fascicularis showed abnormal chest radiographs,an increased body temperature and a decreased body weight.Viral genomes were detected in swab and blood samples from all animals.Viral load was detected in the pulmonary tissues of M.mulatta and M.fascicularis but not C.jacchus.Furthermore,among the three animal species,M.mulatta showed the strongest response to SARS-CoV-2,including increased inflammatory cytokine expression and pathological changes in the pulmonary tissues.Collectively,these data revealed the different susceptibilities of Old World and New World monkeys to SARS-CoV-2 and identified M.mulatta as the most suitable for modeling COVID-19. | Shuaiyao Lu Yuan Zhao Wenhai Yu Yun Yang Jiahong Gao Junbin Wang Dexuan Kuang Mengli Yang Jing Yang Chunxia Ma Jingwen Xu Xingli Qian Haiyan Li Siwen Zhao Jingmei Li Haixuan Wang Haiting Long Jingxian Zhou Fangyu Luo Kaiyun Ding Daoju Wu Yong Zhang Yinliang Dong Yuqin Liu Yinqiu Zheng Xiaochen Lin Li Jiao Huanying Zheng Qing Dai Qiangming Sun Yunzhang Hu Changwen Ke Hongqi Liu Xiaozhong Peng | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 15 | Reemergent Cases of COVID-19--Xinjiang Uygur Autonomous Region,China,July 16,2020显示文摘Before the coronavirus disease 2019(COVID-19)outbreak on July 16,2020,no new COVID-19 cases were reported in Urumqi City of Xinjiang for 150 consecutive days.During this outbreak,826 confirmed COVID-19 cases have been reported in Urumqi.The phylogenetic characteristics of COVID-19 virus from clinical specimens of the initial 4 cases in the Urumqi outbreak were sequenced. | Cao Chen Hemuti Ma Zhiyuan Jia Xiang Zhao Dayan Wang Jun Zhao Zhenguo Gao Peipei Liu Yang Song Zhixiao Chen Yuchao Wu Yao Meng Guizhen Wu Wenbo Xu Xucheng Fan Yong Zhang | 2020 | China CDC weekly2020，2，39： | 5 |
| 16 | A Case of New Variant COVID-19 First Emerging in South Africa Detected in Airplane Pilot—Guangdong Province,China,January 6,2021显示文摘On January 6,2021,Guangdong CDC successfully isolated the 501Y.V2 variant of coronavirus disease 2019(COVID-19)virus from a throat swab of a patient.The 501Y.V2 variant was first detected in South Africa,and the patient is a 55-year-old male airline pilot of South African nationality.He entered Guangzhou City,the capital of Guangdong Province,from Singapore on the evening of December 8,2020 and was subject to a COVID-19 test. | Fengjuan Chen Bosheng Li Peter Hao Yang Song Wenbo Xu Nankun Liu Chunliang Lei Changwen Ke | 2021 | China CDC weekly2021，3，2： | 5 |
| 17 | COVID-19:A Year Long and Beyond?显示文摘In December 2019,a number of patients with pneumonia of unknown etiology(PUE)were reported in Wuhan,Hubei Province(1).The coronavirus disease 2019(COVID-19),caused by a virus also known as severe acute respiratory syndrome coronavirus-2(SARS-CoV-2),was identified by China in January 2020.On January 30,2020,the World Health Organization(WHO)declared coronavirus a public health emergency of international concern(PHEIC). | George F.Gao | 2021 | China CDC weekly2021，3，8： | 4 |
| 18 | RT-PCR测定SARS患者粪便及漱口液中SARS CoV RNA及其临床意义显示文摘目的 对 4 6例SARS患者 2 0 6份粪便及漱口液标本 ,检测SARSCoV ,探讨SARS患者恢复期排毒的情况。方法 对住院的 4 6例临床确诊SARS病人 ,留取粪便及同期漱口液各 10 3份 ,提取RNA后利用 14对SARSCoV特异性引物 ,对每份标本同时进行 7次套式RT PCR扩增 ,凡 1次RT PCR结果阳性 ,该标本即判定为阳性。结果 10 3份粪便标本中 ,6 3份 (6 1.2 % )SARSCoV阴性 ,4 0份(38.8% )阳性 ,阳性者的病程为 30 .75d± 11.2 7d(12d~ 6 4d)。 10 3份漱口液标本中 ,81份 (78.6 % )阴性 ,2 2份 (2 1.4 % )阳性 ,阳性者的病程为 2 9.82d± 12 .4 6d(12d~ 6 4d)。病程最长 6 4d时粪便及漱口液中依然发现SARSCoV病原学依据。患者同期粪便及漱口液RT PCR检测结果一致的有 6 1份(5 9.2 % ) ,不一致的有 4 2份 (40 .8% )。结论 SARS患者恢复期排毒可长达 6 4d ,对SARS患者恢复期的消毒隔离应该得到足够的重视。SARS患者粪便SARSCoVRNA阳性 ,而同期漱口液SARSCoVRNA阴性 ,提示SARSCoV可以直接经消化道传播。 | 任翊 丁惠国 吴清发 陈唯军 陈东 任珍 杨玲 赵春惠 汪健 | 2003 | 中华微生物学和免疫学杂志2003，23，12： | 4 |
| 19 | Keep Healthcare Workers Safe:Application of Teleoperated Robot in Isolation Ward for COVID‑19 Prevention and Control显示文摘At the time of writing,the coronavirus disease(COVID-19)has affected 212 countries and territories across the globe.According to the world health organization(WHO),a total number of 4,735,622 confirmed cases,including 316,289 deaths was reported[1].In the fight against COVID-19,nurses,doctors,and other healthcare workers are in the front line of the battle bearing the higher risk of infection[2].The International Council of Nurses(ICN)gathered further information to suggest that more than 90,000 healthcare workers have been infected worldwide[3].Personal protective equipment(PPE)shortage is one of the key factors increasing the infection risk for the medical staffs.Therefore,finding alternative ways to lower the infection risk has become an urgent problem to be solved. | Geng Yang Honghao Lv Zhiyu Zhang Liu Yang Jia Deng Siqi You Juan Du Huayong Yang | 2020 | Chinese Journal of Mechanical Engineering2020，33，3： | 4 |
| 20 | Fighting Against COVID-19 at the Community Level—Wuhan City,Hubei Province,China,2020显示文摘Since December 2019,an increasing number of cases of pneumonia with unknown etiology(PUE)—later named as coronavirus disease 2019(COVID-19)by the World Health Organization(WHO)—was identified in Wuhan(1–3),a large city of 11 million people in central China,and the basic reproductive number(R0)was estimated to be 2.2(95%CI:1.4 to 3.9)(4).On March 11,2020,the WHO formally announced COVID-19 a worldwide pandemic based on the alarming levels of spread and severity and by the alarming levels of inaction(5).Although there is neither a vaccine nor specific medication available,the pandemic was well contained in China by the strict introduction of nonpharmacological interventions(NPIs)(6). | Canyou Zhang George FGao Zhifeng Wang Hao Wu | 2020 | China CDC weekly2020，2，25： | 4 |
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