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| 1 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 2 | Aerosol and boundary-layer interactions and impact on air quality显示文摘Air quality is concerned with pollutants in both the gas phase and solid or liquid phases. The latter are referred to as aerosols, which are multifaceted agents affecting air quality, weather and climate through many mechanisms. Unlike gas pollutants, aerosols interact strongly with meteorological variables with the strongest interactions taking place in the planetary boundary layer(PBL). The PBL hosting the bulk of aerosols in the lower atmosphere is affected by aerosol radiative effects. Both aerosol scattering and absorption reduce the amount of solar radiation reaching the ground and thus reduce the sensible heat fluxes that drive the diurnal evolution of the PBL. Moreover, aerosols can increase atmospheric stability by inducing a temperature inversion as a result of both scattering and absorption of solar radiation, which suppresses dispersion of pollutants and leads to further increases in aerosol concentration in the lower PBL.Such positive feedback is especially strong during severe pollution events. Knowledge of the PBL is thus crucial for understanding the interactions between air pollution and meteorology. A key question is how the diurnal evolution of the PBL interacts with aerosols, especially in vertical directions, and affects air quality.We review the major advances in aerosol measurements, PBL processes and their interactions with each other through complex feedback mechanisms, and highlight the priorities for future studies. | Zhanqing Li Jianping Guo Aijun Ding Hong Liao Jianjun Liu Yele Sun Tijian Wang Huiwen Xue Hongsheng Zhang Bin Zhu | 2017 | National Science Review2017，4，6： | 37 |
| 3 | Effect of Ce doping of TiO_2 support on NH_3-SCR activity over V_2O_5–WO_3/CeO_2–TiO_2 catalyst显示文摘CeO2–TiO2composite supports with different Ce/Ti molar ratios were prepared by a homogeneous precipitation method, and V2O5–WO3/CeO2–TiO2catalysts for the selective catalytic reduction(SCR) of NOx with NH3 were prepared by an incipient-wetness impregnation method. These catalysts were characterized by means of BET, XRD, UV–Vis,Raman and XPS techniques. The results showed that the catalytic activity of V2O5–WO3/TiO2 was greatly enhanced by Ce doping(molar ratio of Ce/Ti = 1/10) in the TiO2 support.The catalysts that were predominantly anatase TiO2 showed better catalytic performance than the catalysts that were predominantly fluorite CeO2. The Ce additive could enhance the surface adsorbed oxygen and accelerate the SCR reaction. The effects of O2 concentration, ratio of NH3/NO, space velocity and SO2 on the catalytic activity were also investigated. The presence of oxygen played an important role in NO reduction. The optimal ratio of NH3/NO was 1/1 and the catalyst had good resistance to SO2 poisoning. | Kai Cheng Jian Liu Tao Zhang Jianmei Li Zhen Zhao Yuechang Wei Guiyuan Jiang Aijun Duan | 2014 | Journal of Environmental Sciences2014，26，10： | 18 |
| 4 | Sodium humate accelerates cutaneous wound healing by activating TGF-β/Smads signaling pathway in rats显示文摘Sodium humate(HA-Na) has been topically used as a wound healing and anti-inflammatory agent in folk medicine. In the present study, HA-Na was investigated for cutaneous wound healing in Sprague–Dawley rats. HA-Na solution(1.0%, w/v) was topically administered to rats undergoing excision wound models. Healing was assessed with a recombinant bovine basic fibroblast growth factor for external use as positive control. Wound healing rates were calculated on Day 3, 6, 9, 14 and 21 after injury, and tissues were also harvested after the same intervals for histological analysis. In addition, tissue hydroxyproline levels were measured. Furthermore, m RNA levels and protein expressions of transforming growth factor-β1, 2, 3(TGF-β1, 2, 3) were determined by RT-PCR and western blot. Protein expression levels of Smad-2,-3,-4 and-7 were also detected by western blot. Our study demonstrates that HA-Na has the capacity to promote wound healing in rats via accelerated wound contraction and increased hydroxyproline content. More importantly, these wound healing effects of HA-Na might be mediated through the TGF-β/Smad signaling pathway. HA-Na may be an effective agent for enhanced wound healing. | Yuanyuan Ji Aijun Zhang Xiaobin Chen Xiaoxia Che Kai Zhou Zhidong Wang | 2016 | Acta Pharmaceutica Sinica B2016，6，2： | 17 |
| 5 | FY-3E:The First Operational Meteorological Satellite Mission in an Early Morning Orbit显示文摘Fengyun-3 E(FY-3E),the world’s first early-morning-orbit meteorological satellite for civil use,was launched successfully at the Jiuquan Satellite Launch Center on 5 July 2021.The FY-3E satellite will fill the vacancy of the global early-morning-orbit satellite observation,working together with the FY-3C and FY-3D satellites to achieve the data coverage of early morning,morning,and afternoon orbits.The combination of these three satellites will provide global data coverage for numerical weather prediction(NWP)at 6-hour intervals,effectively improving the accuracy and time efficiency of global NWP,which is of great significance to perfect the global earth observing system.In this article,the background and meteorological requirements for the early-morning-orbit satellite are reviewed,and the specifications of the FY-3E satellite,as well as the characteristics of the onboard instrumentation for earth observations,are also introduced.In addition,the ground segment and the retrieved geophysical products are also presented.It is believed that the NWP communities will significantly benefit from an optimal temporal distribution of observations provided by the early morning,mid-morning,and afternoon satellite missions.Further benefits are expected in numerous applications such as the monitoring of severe weather/climate events,the development of improved sampling designs of the diurnal cycle for accurate climate data records,more efficient monitoring of air quality by thermal infrared remote sensing,and the quasicontinuous monitoring of the sun for space weather and climate. | Peng ZHANG Xiuqing HU Qifeng LU Aijun ZHU Manyun LIN Ling SUN Lin CHEN Na XU | 2022 | Advances in Atmospheric Sciences2022，39，1： | 13 |
| 6 | Improved CICA Algorithm Used for Single Channel Compound Fault Diagnosis of Rolling Bearings显示文摘A Compound fault signal usually contains multiple characteristic signals and strong confusion noise, which makes it difficult to separate week fault signals from them through conventional ways, such as FFT-based envelope detection, wavelet transform or empirical mode decomposition individually. In order to realize single channel compound fault diagnosis of bearings and improve the diagnosis accuracy, an improved CICA algorithm named constrained independent component analysis based on the energy method(E-CICA) is proposed. With the approach, the single channel vibration signal is firstly decomposed into several wavelet coefficients by discrete wavelet transform(DWT) method for the purpose of obtaining multichannel signals. Then the envelope signals of the reconstructed wavelet coefficients are selected as the input of E-CICA algorithm, which fulfills the requirements that the number of sensors is greater than or equal to that of the source signals and makes it more suitable to be processed by CICA strategy. The frequency energy ratio(ER) of each wavelet reconstructed signal to the total energy of the given synchronous signal is calculated, and then the synchronous signal with maximum ER value is set as the reference signal accordingly. By this way, the reference signal contains a priori knowledge of fault source signal and the influence on fault signal extraction accuracy which is caused by the initial phase angle and the duty ratio of the reference signal in the traditional CICA algorithm is avoided. Experimental results show that E-CICA algorithm can effectively separate out the outer-race defect and the rollers defect from the single channel compound fault and fulfill the needs of compound fault diagnosis of rolling bearings, and the running time is 0.12% of that of the traditional CICA algorithm and the extraction accuracy is 1.4 times of that of CICA as well. The proposed research provides a new method to separate single channel compound fault signals. | CHEN Guohua QIE Longfei ZHANG Aijun HAN Jin | 2016 | Chinese Journal of Mechanical Engineering2016，29，1： | 12 |
| 7 | Dynamic contrast-enhanced MRI versus ^(18)F-FDG PET/CT: Which is better in differentiation between malignant and benign solitary pulmonary nodules?显示文摘Objective: To prospectively compare the discriminative capacity of dynamic contrast enhanced-magnetic resonance imaging(DCE-MRI) with that of ^(18)F-fluorodeoxyglucose(^(18)F-FDG) positron emission tomography/computed tomography(PET/CT) in the differentiation of malignant and benign solitary pulmonary nodules(SPNs).Methods: Forty-nine patients with SPNs were included in this prospective study. Thirty-two of the patients had malignant SPNs, while the other 17 had benign SPNs. All these patients underwent DCE-MRI and ^(18)F-FDG PET/CT examinations. The quantitative MRI pharmacokinetic parameters, including the trans-endothelial transfer constant(K^(trans)), redistribution rate constant(K_(ep)), and fractional volume(Ve), were calculated using the Extended-Tofts Linear two-compartment model. The ^(18)F-FDG PET/CT parameter, maximum standardized uptake value(SUV_(max)), was also measured. Spearman's correlations were calculated between the MRI pharmacokinetic parameters and the SUV_(max) of each SPN. These parameters were statistically compared between the malignant and benign nodules. Receiver operating characteristic(ROC) analyses were used to compare the diagnostic capability between the DCE-MRI and ^(18)F-FDG PET/CT indexes.Results: Positive correlations were found between K^(trans) and SUV_(max), and between K_(ep) and SUV_(max)(P<0.05).There were significant differences between the malignant and benign nodules in terms of the K^(trans), K_(ep) and SUV_(max) values(P<0.05). The areas under the ROC curve(AUC) of K^(trans), K_(ep) and SUV_(max) between the malignant and benign nodules were 0.909, 0.838 and 0.759, respectively. The sensitivity and specificity in differentiating malignant from benign SPNs were 90.6% and 82.4% for K^(trans); 87.5% and 76.5% for K_(ep); and 75.0% and 70.6%for SUV_(max), respectively. The sensitivity and specificity of K^(trans) and K_(ep) were higher than those of SUV_(max), but there was no significant difference between them(P>0.05).Conclusions: DCE-MRI can be used to differentiate between benign and malignant SPNs and has the advantage of being radiation free. | Feng Feng Fulin Qiang Aijun Shen Donghui Shi Aiyan Fu Haiming Li Mingzhu Zhang Ganlin Xia Peng Cao | 2018 | Chinese Journal of Cancer Research2018，30，1： | 10 |
| 8 | Microstructure, tensile properties and mechanical anisotropy of selective laser melted 304L stainless steel显示文摘The microstructure and mechanical properties of 304 L stainless steel fabricated by selective laser melting are investigated in this study.With the optimized laser processing parameters,a relative density of 99.9%is achieved with fine austenite grains and nanoscale cellular subgrains in size of approximately 0.5μm.The presence ofδ-ferrite andσphase precipitates is identified by the x-ray diffraction and transmission electron microscopy.Moreover,the microstructure is identified as an austenite matrix with about 4%δ-ferrite and a trace amount ofσphase by using electron backscattered diffraction analysis.These smallσphase particles are mainly distributed along austenite grain boundaries.Furthermore,the presence of nanoscale cellular subgrains contributes to the good tensile strength and ductility of the selective laser melted 304 L,along with precipitate strengthening and strain hardening.Tensile property anisotropy is also identified in this 304 L,which is attributed to the microstructure difference on vertical and horizontal planes. | Juan Hou Wei Chen Zhuoer Chen Kai Zhang Aijun Huang | 2020 | Journal of Materials Science & Technology2020，47，13： | 10 |
| 9 | A Transgenic Study on Affecting Potato Tuber Yield by Expressing the Rice Sucrose Transporter Genes OsSUT5Z and OsSUT2M显示文摘在许多植物,蔗糖 transporters 为从来源和进口的两个蔗糖出口是必要的进水池,显示功能在吸收划分。为了调查蔗糖 transporters 是否能改进淀粉的收益,种,土豆植物(茄属 tuberosum L。cv。 | Aijun Sun Yan Dai Xinsheng Zhang Chunmin Li Kun Meng Honglin Xu Xiaoli Wei Guifang Xiao Pieter B.F, Ouwerkerk Mei Wang Zhen Zhu | 2011 | Journal of Integrative Plant Biology2011，53，7： | 9 |
| 10 | Expert consensus on the glycemic management of critically ill patients显示文摘Introduction The incidence of hyperglycemia is 40-60%in critically ill patients and is up to 60-80%in those who have undergone car-diac surgery.[1]The results of an epidemiological study in the United States showed that 28.6%of diabetic patients and 9.3%of non-diabetic patients had elevated mean daily glucose on the day of ICU admission.[2]In critically ill patients,elevated blood glucose is primarily the result of stress,and stress-induced hy-perglycemia is an independent risk factor associated with prog-nosis,regardless of a previous diagnosis of diabetes.Nutritional therapy has become an integral treatment option for patients in the ICU,[3,4]though nearly 30%of patients with enteral nu-trition and 44-50%with parenteral nutrition(PN)experience elevated glucose.[5,6]Intensive insulin therapy(IIT)is an impor-tant treatment for controlling hyperglycemia in critically ill pa-tients,but it also carries a corresponding risk of hypoglycemia. | Zhixiong Wu Jiao Liu Dong Zhang Kai Kang Xiangrong Zuo Qianghong Xu Aijun Pan Wei Fang Fen Liu You Shang Haiyan Yin Juntao Hu Jinglun Liu Jiangquan Fu Wei Zhang Yuan Zong Min Shao Feng Zhao Mei Meng Yanfei Mao Yingchuan Li Dechang Chen | 2022 | Journal of Intensive Medicine2022，2，3： | 9 |
| 11 | Organic-inorganic bismuth (lll)-based material: A lead- free, air-stable and solution-processable light-absorber beyond organolead perovskites显示文摘 | Miaoqiang Lyu Jung-Ho Yun Molang Cai Yalong Jiao Paul V. Bernhardt Meng Zhang Qiong Wang Aijun Du Hongxia Wang Gang Liu Lianzhou Wang | 2016 | Nano Research2016，9，3： | 8 |
| 12 | Single Pt atom decorated graphitic carbon nitride as an efficient photocatalyst for the hydrogenation of nitrobenzene into aniline显示文摘The hydrogenation of nitrobenzene into aniline is one of industrially important reactions, but still remains great challenge due to the lack of highly active, chemo-selective and eco-friendly catalyst. By using extensive density functional theory (DFT) calculations, herein we predict that single Pt atom decorated g-C3N4 (Pt@g-C3N4) exhibits excellent catalytic activity and selectivity for the conversion of nitrobenzene into aniline under visible light. The overall activation energy barrier for the hydrogenation of nitrobenzene on single atom Pt@g-C3N4 catalyst is even lower than that of the bare Pt(111) surface. The dissociation of N-0 bonds on single Pt atom is triggered by single hydrogen atom rather than double hydrogen atoms on the Pt(111) surface. Moreover, the Pt@g-C3N4 catalyst exhibits outstanding chemoselectivity towards the common reducible substituents, such as phenyl,-C=C,-C = C and -CHO groups during the hydrogenation. In addition, the doped single Pt atom can significantly enhance the photoconversion efficiency by broadening the light absorption of the pristine g-C3N4 to visible light region. Our results highlight an interesting and experimentally synthesized single-atom photocatalyst (Pt@g-C3N4) for efficient hydrogenation of nitrobenzene to aniline under a sustainable and green approach. | Tianwei He Chunmei Zhang Lei Zhang Aijun Du | 2019 | Nano Research2019，12，8： | 8 |
| 13 | The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases显示文摘N6-methyladenosine(m6A)RNA methylation is an emerging area of epigenetics,which is a reversible and dynamic modification mediating by‘writers’(methylase,adding methyl groups,METTL3,METTL14,and WTAP),‘erasers’(demethylase,deleting methyl groups,FTO and ALKBH5),and‘readers’(YTHDF1-3,YTHDC1 and YTHDC2).Recent studies in human,animal models and cell levels have disclosed a critical role of m6A modification in regulating the homeostasis of metabolic processes and cardiovascular function.Evidence from these studies identify m6A as a candidate of biomarker and therapeutic target for metabolic abnormality and cardiovascular diseases(CVD).Comprehensive understanding of the complexity of m6A regulation in metabolic diseases and CVD will be helpful for us to understand the pathogenesis of CVD.In this review,we discuss the regulatory role of m6A in metabolic abnormality and CVD.We will emphasize the clinical relevance of m6A dysregulation in CVD. | Beijian Zhang Hao Jiang Zhen Dong Aijun Sun Junbo Ge | 2021 | Genes & Diseases2021，8，6： | 8 |
| 14 | Regional Characteristics and Causes of Haze Events in Northeast China显示文摘Northeast China experiences severe atmospheric pollution, with an increasing occurrence of heavy haze episodes. However, the underlying forces driving haze formation during different seasons are poorly understood. In this study, we explored the spatio-temporal characteristics and causes of haze events in Northeast China by combining a range of data sources(i.e., ground monitoring, satellite-based products, and meteorological products). It was found that the ‘Shenyang-Changchun-Harbin(SCH)'city belt was the most polluted area in the region on an annual scale. The spatial distribution of air quality index(AQI) values had a clear seasonality, with the worst pollution occurring in winter, an approximately oval-shaped polluted area around western Jilin Province in spring, and the best air quality occurring in summer and most of the autumn. The three periods that typically experienced intense haze events were Period I from mid-October to mid-November(i.e., late autumn and early winter), Period II from late-December to February(i.e., the coldest time in winter), and Period III from April to mid-May(i.e., spring). During Period I, strong PM_(2.5) emissions from seasonal crop residue burning and coal burning for winter heating were the dominant reasons for the occurrence of extreme haze events(AQI > 300). Period II had frequent heavy haze events(200 < AQI < 300) in the coldest months of January and February, which were due to high PM_(2.5) emissions from coal burning and vehicle fuel consumption, a lower atmospheric boundary layer, and stagnant atmospheric conditions. Haze events in Period III, with high PM_(10) concentrations, were primarily caused by the regional transportation of windblown dust from degraded grassland in central Inner Mongolia and bare soil in western Jilin Province. Local agricultural tilling could also release PM_(10) and enhance the levels of windblown dust from tilled soil. Better control of coal burning, fuel consumption, and crop residue burning in winter and autumn is urgently needed to address the haze problem in Northeast China. | CHEN Weiwei ZHANG Shichun TONG Quansong ZHANG Xuelei ZHAO Hongmei MA Siqi XIU Aijun HE Yuexin | 2018 | Chinese Geographical Science2018，28，5： | 7 |
| 15 | 2-Gy whole-body irradiation significantly alters the balance of CD4^(+)CD25^(-) T effector cells and CD4^(+)CD25^(+)Foxp3^(+) T regulatory cells in mice显示文摘CD4^(+)CD25^(+) T regulatory(Treg)cells are critical in inducing and maintaining immunological self-tolerance as well as transplant tolerance.The effect of low doses of whole-body irradiation(WBI)on CD41CD251Foxp31 Treg cells has not been determined.The proportion,phenotypes and function of CD4^(+)CD25^(+) Treg cells were investigated 0.5,5 and 15 days after euthymic,thymectomized or allogeneic bone marrow transplanted C57BL/6 mice received 2-Gy c-rays of WBI.The 2-Gy WBI significantly enhanced the ratios of CD41CD251 Treg cells and CD4^(+)CD25^(+)Foxp3^(+) Treg cells to CD41 T cells in peripheral blood,lymph nodes,spleens and thymi of mice.The CD41CD251 Treg cells of the WBI-treated mice showed immunosuppressive activities on the immune response of CD4^(+)CD25^(+) T effector cells to alloantigens or mitogens as efficiently as the control mice.Furthermore,2-Gy c-ray WBI significantly increased the percentage of CD4^(+)CD25^(+)Foxp3^(+) Treg cells in the periphery of either thymectomized mice or allogeneic bone marrow transplanted mice.The in vitro assay showed that ionizing irradiation induced less cell death in CD4^(+)CD25^(+)Foxp3^(+) Treg cells than in CD4^(+)CD25^(+) T cells.Thus,a low dose of WBI could significantly enhance the level of functional CD41CD251Foxp31 Treg cells in the periphery of naive or immunized mice.The enhanced proportion of CD41CD251Foxp31 Treg cells in the periphery by a low dose of WBI may make hosts more susceptible to immune tolerance induction. | Yanyan Qu Baojun Zhang Shuchun Liu Aijun Zhang Tingting Wu Yong Zhao | 2010 | Cellular & Molecular Immunology2010，7，6： | 7 |
| 16 | Dendrite‐free lithium and sodium metal anodes with deep plating/stripping properties for lithium and sodium batteries显示文摘Although lithium(Li)and sodium(Na)metals can be selected as the promising anode materials for next‐generation rechargeable batteries of high energy density,their practical applications are greatly restricted by the uncontrollable dendrite growth.Herein,a platinum(Pt)–copper(Cu)alloycoated Cu foam(Pt–Cu foam)is prepared and then used as the substrate for Li and Na metal anodes.Owing to the ultrarough morphology with a threedimensional porous structure and the quite large surface area as well as lithiophilicity and sodiophilicity,both Li and Na dendrite growths are significantly suppressed on the substrate.Moreover,during Li plating,the lithiated Pt atoms can dissolve into Li phase,leaving a lot of microsized holes on the substrate.During Na plating,although the sodiated Pt atoms cannot dissolve into Na phase,the sodiation of Pt atoms elevates many microsized blocks above the current collector.Either the holes or the voids on the surface of Pt–Cu foam what can be extra place for deposited alkali metal,what effectively relaxes the internal stress caused by the volume exchange during Li and Na plating/stripping.Therefore,the symmetric batteries of Li@Pt–Cu foam and Na@Pt–Cu foam have both achieved long‐term cycling stability even at ultrahigh areal capacity at 20 mAh cm−2. | Jianyi Wang Qi Kang Jingchao Yuan Qianru Fu Chunhua Chen Zibo Zhai Yang Liu Wei Yan Aijun Li Jiujun Zhang | 2021 | Carbon Energy2021，3，1： | 6 |
| 17 | m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure显示文摘Dear Editor,N6-methyladenosine(m6A)is the most common posttranscriptional mammalian mRNA modification involved in multiple biological processes and diseases.1 However,its role in cardiac energy metabolism changes during heart failure(HF)remains elusive.Here we explored the role of m6A demethylase fat mass and obesity-associated protein(FTO)in glucose metabolism during pressure overload-induced HF.Methylated RNA immunoprecipitation sequencing(MeRIP-seq)was performed to map transcriptome-wide m6A modifications in transverse aortic constriction(TAC)and sham hearts.The number of identified m6A peaks was higher in the TAC than in the sham hearts(Fig.1a).Consistent with previous reports,the m6A peaks were enriched in 3’-untranslated regions in both the TAC and sham hearts(Fig.1b).2 The m6A peaks were characterized by the canonical RGAAR(R=A or G)motif(Fig.1c). | Beijian Zhang Hao Jiang Jian Wu Yun Cai Zhen Dong Yongchao Zhao Qinfeng Hu Kai Hu Aijun Sun Junbo Ge | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 6 |
| 18 | Hybrid customer requirements rating method for customer-oriented product design using QFD显示文摘Quality function deployment(QFD) is a well-known customer-oriented product design methodology. Rating the final importance of customer requirements(CRs) is really a very essential starting point in the implementation of QFD, since it largely affects the target setting value of design requirements. This paper aims to propose a novel method to deal with the relative importance ratings(RIRs) of CRs problem considering customers' diversified requirements and unknown information on customers' weights, which is an indispensable process for determining the final importance ratings of CRs. First, a new concept of customer's assessment structure is proposed according to the basic idea of grey relational analysis(GRA), and then a constrained nonlinear optimization model is constructed to describe the assessment information aggregation factors of CRs considering customers' personalized and diversified requirements. Furthermore, an immune particle swarm optimization(IPSO) algorithm is designed to solve the model, and the weight vector of customers is obtained.Finally, a car door design example is introduced to illustrate the novel hybrid GRA-IPSO method's potential application in determining the RIRs of CRs. | Fang Wang Hua Li Aijun Liu Xiao Zhang | 2015 | Journal of Systems Engineering and Electronics2015，26，3： | 6 |
| 19 | High efficiency all-dielectric pixelated metasurface for near-infrared full-Stokes polarization detection显示文摘Pixelated metasurfaces integrating both the functions of linear polarization and circular polarization filters on a single platform can achieve full-Stokes polarization detection.At present,the pixelated full-Stokes metasurfaces mainly face the following problems:low transmission,low circular dichroism(CD)of circular polarization filters,and high requirements in fabrication and integration.Herein,we propose high performance ultracompact all-dielectric pixelated full-Stokes metasurfaces in the near-infrared band based on silicon-on-insulator,which is compatible with the available semiconductor industry technologies.Circular polarization filters with high CD are achieved by using simple two-dimensional chiral structures,which can be easily integrated with the linear polarization filters on a single chip.In addition,the dielectric materials have higher transmission than metal materials with intrinsic absorption.We experimentally demonstrated the circular polarization filter with maximum CD up to 70%at a wavelength of 1.6μm and average transmission efficiency above 80%from 1.48μm to 1.6μm.Therefore,our design is highly desirable for many applications,such as target detection,clinical diagnosis,and polarimetric imaging and sensing. | Chong Zhang Jingpei Hu Yangeng Dong Aijun Zeng Huijie Huang Chinhua Wang | 2021 | Photonics Research2021，9，4： | 6 |
| 20 | Deficiency of Mouse CD4^+CD25^+Foxp3^+ Regulatory T Cells in Xenogeneic Pig Thymus-Grafted Nude Mice Suffering from Autoimmune Diseases显示文摘Xenogeneic thymus transplantation can efficiently induce specific immune tolerance to donor antigens in athymic recipients. However, many nude mice suffer from autoimmune diseases (AID) for over 10 weeks after xenogeneic thymus transplantation. CD4+CD25+Foxp3+ regulatory T (Treg) cells were recently determined to play a pivotal role in keeping immune tolerance in humans and mice. Thus, we investigated this subpopulation of Treg cells in the periphery of pig thymus-grafted nude mice suffering from AID. Our results showed that the expression of Foxp3, CTLA-4 and GITR on mouse CD4+CD25+ T cells and the ratio of CD4+CD25+Foxp3+ Treg cells to CD4+ T cells were significantly decreased in the periphery of pig thymus-grafted nude mice suffering from AID, compared with healthy pig or mouse thymus-grafted nude mice. Furthermore, mouse CD4+CD25+ T cells in pig thymus-grafted nude mice suffering from AID showed more severe deficiency in immunosuppressive function compared with the counterpart in xenogeneic pig or syngeneic thymus-grafted nude mice without AID. Thus, the decreased frequency, altered phenotype and functional deficiency of mouse CD4+CD25+ Treg cells in pig thymus-grafted nude mice may contribute to the development of AID in this model. | Baojun Zhang Chenming Sun Yanyan Qu Aijun Zhang Jun Liu Lianjun Zhang Zeqing Niu Yong Zhao | 2008 | Cellular & Molecular Immunology2008，5，5： | 6 |
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