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| 1 | Application of rare earths in fluid catalytic cracking: A review显示文摘The need for more active and hydrothermally stable fluid catalytic cracking(FCC)catalysts to combat the effect of metal contaminants has led to an increase in demand for rare earth oxides.Rare earth oxides enhance catalyst activity and prevent the loss of acid sites during the FCC unit operation,especially when heavy residue with high metal content is used as feed.In this paper,a review was carried out to show the effects of rare earth elements on the structure,activity,and stability of FCC catalysts.Also,the use of rare earth elements as vanadium traps was analyzed in conjunction with the mechanism of catalyst deactivation by vanadium.The objective was to elucidate the interaction of vanadium species with the zeolite component of the FCC catalysts and the role of rare earth elements in countering the deleterious effects of vanadium on the FCC catalysts. | Aaron Akah | 2017 | Journal of Rare Earths2017，35，10： | 15 |
| 2 | Antimicrobial and antispasmodic activity of leaf extract and fractions of Stachytarpheta cayennensis显示文摘Objective:To investigate the antimicrobial activity of the methanol leaf extract(ME),n-hexane fraction(HF),ethylacetate fraction(EF) and methanol fraction(MF),of Stachytarpheta cayennensis C.Rich(verbenaceae) as well as to ascertain the antispasmodic effects of the ME and the various fractions(HF,EF and MF) on acetylcholine(Ach) and histamine(H) induced contractions on isolated guinea pig ileum.Methods:The in vitro agar well diffusion method was used for the antimicrobial studies while the isolated tissue method was employed for the antispasmodic test. Organisms used were all clinical isolates of Bacillus subtilis,Staphylococcus aureus,Pseudomonas aeruginosa,Salmonella paratyphi,Candida albicans and Aspergillus niger.Results:The extract and fractions exhibited dose dependent inhibition against all the bacteria tested and also exhibited insignificant antifungal activity against Candida albicans and Aspergillus niger.The minimum inhibitory concentration(MIC) of the extract and fractions(mg/mL) on Bacillus subtilis, Staphylococcus aureus,Pseudomonas aeruginosa and Salmonella paratyphi respectively were ME 5.62,14.12,22.38,2.11;EF 1.25,6.30,9.40,9.40 and MF 3.98,8.81,39.80,21.13.The n-hexane fraction exhibited MIC of 1.07 mg/mL against only Bacillus subtilis.The extract and fractions exhibited significant(P< 0.05) dose dependent attenuation of contractions induced by acetylcholine and histamine on isolated guinea pig ileum.Concentrations of the extract and fractions(μg/mL) which evoked 50%inhibition of maximal response exhibited by Ach were ME 0.64,HF 0.16,EF 0.08 and MF 0.15,while that of histamine included ME 5.12,HF 0.16,EF 0.04 and MF 0.64.Preliminary phytochemical studies on the extract and fractions indicated the presence of carbohydrates,alkaloids,saponins,flavonoids,steroids and terpenoids.Conclusions: The extract and fractions of Stachytarpheta cayennensis possessed both antibacterial and antispasmodic effects confirming the claimed use in folkloric medicine for wound healing and gastrointestinal ulceration. | Okoye TC Akah PA Okoli CO Ezike AC Mbaoji FN | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，3： | 3 |
| 3 | The role of Al and strong acidity in the selective catalytic oxidation of NH3 over Fe-ZSM 5 显示文摘 | AKAH A C NKENG G GARFORTH A A | 2007 | Appl Catal B Environ2007，74，12： | 1 |
| 4 | Dioscoretine: the Hypoglycemic Principle of Dioscorea Dumetorum显示文摘 | IWU M M OKUNJI C O AKAH P | 1990 | Planta Med1990，56，1： | 1 |
| 5 | Immunomudulatory activities of kolaviron, a mixture of three related biflavonoids of Garcinia kola Heckel显示文摘 | Nworu CS Akah PA Esimone CO | 2008 | Immunopharmacol Immunotoxicol2008，30，2： | 1 |
| 6 | Acanthusmontanus : an experimental evaluation of the antimi-crobial, anti-inflammatory and immunological prop-erties of a traditional remedy for furuncles显示文摘 | Okoli CO Akah PA Onuoha NJ | 2008 | BMCComplement Altern Med2008，8，： | 1 |
| 7 | Carieapapaya (paw paw) unripe fruit may be benefieial in ulcer 显示文摘 | AC Ezike P Akah C Okoli | 2009 | J Med Food2009，12，6： | 1 |
| 8 | Central inhibitory activi- ty of the aqueous extract of Crinum giganteum 显示文摘 | AMOS S BINDA L AKAH P | 2003 | Fitoterepia2003，74，12： | 1 |
| 9 | Dioscoretine: the hypoglycemic principle of Dioscorea dumetorum 显示文摘 | Iwu MM Okunji CO Akah P | 1990 | Ptanta Med1990，56，1： | 1 |
| 10 | Mechanisms of the anti-inflammatory activity of the leaf extracts of Culcasia scandens P. Beauv (Araceae)显示文摘 | Charles O. Okoli Peter A. Akah | 2004 | Pharmacology Biochemistry and Behavior2004，，3： | 1 |
| 11 | Dioscoretine:the hypoglycemic principle of dioscorea dumetorum显示文摘 | IWU M M OKUNJI C O AKAH P | 1990 | Planta Med1990，56，1： | 1 |
| 12 | Sphodea campanula: An ex- perimental evaluation of the analgesic and an- ti-inflammatory properties of a traditional reme- dy 显示文摘 | Ilodigwe E E Akah P A | 2009 | Asian J Med Sci2009，1，2： | 1 |
| 13 | Potentials of leaves of Aspilia africana (Compositae) in wound care: an experimental evaluation显示文摘 | OKOLI C AKAH P OKOLI A | 2007 | BMC Complementary and Alternative Medicine2007，7，1： | 1 |
| 14 | Evaluation of the acute and sub acute toxicity of Annona senegalensis root bark extracts显示文摘Objective:To investigate the safety profile of Annona senegalensis(A.senegalensis).Methods: Dried powdered root-bark of A.senegalensis was prepared by Sohxlet extraction using methanolmethylene chloride(1:1) solution and concentrated to obtain the methanol-methylene chloride extract(MME).MME was fractionated to obtain the n-hexane(HF),ethylacetate(EF) and methanol(MF) fractions.Acute toxicity(LD50) test was performed with MME,HF,EF and MF in mice by oral route.The sub acute toxicity studies were performed in rats after 14 days of MME administration while haemalological and biochemical parameters were monitored.Results: Medium lethal(LD-(50)) values of 1 296.3 808.1 265 and 2 154 mg/kg were obtained for the MME.MF, HF and EF,respectively.The sub-acute toxicity studies indicated a significant(P<0.05) increase in the body weight of both the treated rats and the control.The haematological tests indicated no change in the packed cell volume values but a significant(P<0.05) increase in the total WBC count at 100 and 400 mg/kg doses.The differential analysis showed a decrease in the nutrophils and a non-significant increase in the lymphocyte counts.The liver transaminase enzymes, alanin transaminase and aspartate transaminase showed no significant increase compared to the control.Histopathological examination of the liver sections also indicted no obvious signs of hepatotoxicity except with the 400 mg/kg dose that showed degeneration and necrosis of the hepatocytes.Conclusions:These results indicated that the root bark extracts of A.Senegalensis are safe at the lower doses tested,and calls for caution in use at higher doses in treatment. | Theophine C Okoye Peter A Akah Adaobi C Ezike Maureen O Okoye Collins A Onyeto Frankline Ndukwu Ejike Ohaegbulam Lovelyn Ikele | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，4： | 1 |
| 15 | Dioscoretine:the hypoglycomie principle of Dioecorea dumetorum显示文摘 | Iwu MM Okunji C O Akah P el al | 1990 | Planta Med1990，56，1： | 1 |
| 16 | Potentials of leaves of Aspilia africana(Compositae ) in wound care:an experimental evaluation显示文摘 | Okoli C O Akah P A Okoli A S | 2007 | BMC Complementary and Alternative Medicine2007，7，1： | 1 |
| 17 | Dioscoretine:The hypoglycemic principle of Dioscorea dumetorum 显示文摘 | Iwu M M Okunji C O Akah P | 1990 | Planta Medi1990，56，1： | 1 |
| 18 | Dioscoretine:the hypoglycemic principle of Dioscorea dumetorum 显示文摘 | IWU M M OKUNJI C O AKAH P | 1990 | Planta Med1990，56，1： | 1 |
| 19 | Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri显示文摘 | C.O. Okoli I.C. Obidike A.C. Ezike P.A. Akah O.A. Salawu | 2011 | Pharmaceutical Biology2011，，3： | 1 |
| 20 | Investigation of high-qchannel drop fil sers using donortype defects in two- dimensional photonic crystal slabs 显示文摘 | Akah Ane Y As Ano T Song B S | 2003 | Appl Phys Lett2003，83，8： | 1 |
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