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| 1 | The Reference Genome of Tea Plant and Resequencing of 81 Diverse Accessions Provide Insights into Its Genome Evolution and Adaptation显示文摘Tea plant is an important economic crop,which is used to produce the world's oldest and most widely consumed tea beverages.Here,we present a high-quality reference genome assembly of the tea plant(Camellia sinensis var.sinensis)consisting of 15 pseudo-chromosomes.LTR retrotransposons(LTR-RTs)account for 70.38%of the genome,and we present evidence that LTR-RTS play critical roles in genome size expansion and the transcriptional diversification of tea plant genes through preferential insertion in promoter regions and introns.Genes,particularly those coding for terpene biosynthesis pro-teins,associated with tea aroma and stress resistance were significantly amplified through recent tandem duplications and exist as gene clusters in tea plant genome.Phylogenetic analysis of the sequences of 81 tea plant accessions with diverse origins revealed three well-differentiated tea plant populations,support-ing the proposition for the southwest origin of the Chinese cultivated tea plant and its later spread to western Asia through introduction.Domestication and modern breeding left significant signatures on hundreds of genes in the tea plant genome,particularly those associated with tea quality and stress resis-tance.The genomic sequences of the reported reference and resequenced tea plant accessions provide valuable resources for future functional genomics study and molecular breeding of improved cul-tivars of tea plants. | Enhua Xia Wei Tong Yan Hou Yanlin An Linbo Chen Qiong Wu Yunlong Liu Jie Yu Fangdong Li Ruopei Li Penghui Li Huijuan Zhao Ruoheng Ge Jin Huang Ali Inayat Mallano Yanrui Zhang Shengrui Liu Weiwei Deng Chuankui Song Zhaoliang Zhang Jian Zhao Shu Wei Zhengzhu Zhang Tao Xia Chaoling Wei Xiaochun Wan | 2020 | Molecular Plant2020，13，7： | 51 |
| 2 | Effects of particle size on crushing and deformation behaviors of rockfill materials显示文摘Strength and deformation behaviors of rockfill materials,key factors for determining the stability of dams,pertain strongly to the grain crushing characteristics.In this study,single-particle crushing tests were carried out on rockfill materials with nominal particle diameters of 2.5 mm,5 mm and 10 mm to investigate the particle size effect on the single-particle strength and the relationship between the characteristic stress and probability of non-failure.Test data were found to be described by the Weibull distribution with the Weibull modulus of 3.24.Assemblies with uniform nominal grains were then subjected to one-dimensional compression tests at eight levels of vertical stress with a maximum of 100 MPa.The yield stress in one-dimensional compression tests increased with decreasing the particle size,which could be estimated from the single-particle crushing tests.The void ratio-vertical stress curve could be predicted by an exponential function.The particle size distribution curve increased obviously with applied stresses less than 16 MPa and gradually reached the ultimate fractal grading.The relative breakage index became constant with stress up to 64 MPa and was obtained from the ultimate grading at the fractal dimension(a?2:7).A hyperbolical function was also found useful for describing the relationship between the relative breakage index and input work during one-dimensional compression tests. | Yang Xiao Minqiang Meng Ali Daouadji Qingsheng Chen ZhijunWu Xiang Jiang | 2020 | Geoscience Frontiers2020，11，2： | 17 |
| 3 | ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13显示文摘这研究的目的是在房间增长和肺腺癌的 autophagy 调查 apelin 的角色。在肺腺癌的 APJ 的在表示上被 immunohistochemistry 检测,当在肺癌症病人的血浆 apelin 水平被连接酶的 immunosorbent 试金测量时。我们的调查结果表明 apelin-13 显著地增加了 ERK1/2 的 phosphorylation, cyclin D1 的表示,联系微导管的蛋白质 1 轻链 3A/B (LC3A/B ) ,和 beclin1,并且证实 apelin-13 支持了 A549 房间增长并且经由 ERK1/2 发信号导致了 A549 房间 autophagy。而且,人的肺腺癌房间线 A549 的表面和光滑、光滑的 apelin-13 原因房间表面上有毛孔是在原子力量下面观察了显微镜学。这些结果建议 ERK1/2 发信号小径调停 apelin-13-induced 肺腺癌房间增长和 autophagy。在我们的试验性的条件下面,与 3-methyladenine 联系的 autophagy 不涉及房间增长。 | Li Yang Tao Su Deguan Lv FengXie Wei Liu Jiangang Cao Irshad Ali Sheikh Xuping Qin Lanfang Li Linxi Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 15 |
| 4 | Cytotoxic genes from traditional Chinese medicine inhibit tumor growth both in vitro and in vivo显示文摘OBJECTIVE: Little effort has been made to study the protein-encoding genes isolated from traditional Chinese medicine(TCM) drugs, and the delivery of these genes into malignant cells through recombinant adeno-associated virus(r AAV) vectors has not been attempted. METHODS: We synthesized the c DNAs of five known cytotoxic proteins isolated from TCM drugs and the FLAG epitope-tagged c DNAs were subcloned into a r AAV plasmid vector. The protein expression was confi rmed by Western blot assay. Various cancer cell lines were transfected with the above plasmids and cell growth was monitored both in vitro and in vivo. The best cytotoxic gene was further packaged into r AAV vectors, under the control of a liver cancer-specifi c promoter. The liver tumor growth was then monitored following intratumor administration of the r AAV vectors.RESULTS: The expression plasmids, encoding individual potential cytotoxic genes tagged with FLAG epitope, were successfully generated and sequenced. Among these genes, trichosanthin(TCS) gene yielded the most promising results for the inhibition of cancer cell growth in vitro. The over-expressed TCS functioned as a type I ribosome-inactivating protein, followed by inducing apoptosis that is associated with the Bcl-PARP signaling pathway. Furthermore, intratumor injection of r AAV vectors containing the TCS gene signifi cantly inhibited the growth of human hepatocellular carcinoma tumors in a murine xenograft model.CONCLUSION: Our studies suggest that the use of TCM cytotoxic genes is a useful therapeutic strategy for treating human cancers in general, and liver tumors in particular. | Yuan-hui Zhang Yuan Wang Ali Hussein Yusufali Frederick Ashby Daniel Zhang Zi-fei Yin George V.Aslanidi Arun Srivastava Chang-quan Ling Chen Ling | 2014 | Journal of Integrative Medicine2014，12，6： | 14 |
| 5 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
| 6 | Nature-inspired chiral metasurfaces for circular polarization detection and full-Stokes polarimetric measurements显示文摘The manipulation and characterization of light polarization states are essential for many applications in quantum communication and computing,spectroscopy,bioinspired navigation,and imaging.Chiral metamaterials and metasurfaces facilitate ultracompact devices for circularly polarized light generation,manipulation,and detection.Herein,we report bioinspired chiral metasurfaces with both strong chiral optical effects and low insertion loss.We experimentally demonstrated submicron-thick circularly polarized light filters with peak extinction ratios up to 35 and maximum transmission efficiencies close to 80% at near-infrared wavelengths(the best operational wavelengths can be engineered in the range of 1.3-1.6μm).We also monolithically integrated the microscale circular polarization filters with linear polarization filters to perform full-Stokes polarimetric measurements of light with arbitrary polarization states.With the advantages of easy on-chip integration,ultracompact footprints,scalability,and broad wavelength coverage,our designs hold great promise for facilitating chip-integrated polarimeters and polarimetric imaging systems for quantum-based optical computing and information processing,circular dichroism spectroscopy,biomedical diagnosis,and remote sensing applications. | Ali Basiri Xiahui Chen Jing Bai Pouya Amrollahi Joe Carpenter Zachary Holman Chao Wang Yu Yao | 2019 | Light(Science & Applications)2019，8，1： | 12 |
| 7 | Extended central hepatectomy with preservation of segment 6 for patients with centrally located hepatocellular carcinoma显示文摘BACKGROUND: In order to preserve functional liver parenchyma, extended central hepatectomy (segments 4, 5, 7 and 8 resection) was proposed for the management of centrally located hepatocellular carcinoma invading the right and middle hepatic veins, reconstructing segment 6 outflow in the absence of the thick inferior right hepatic vein. The present study was to describe our surgical techniques of extended central hepatectomy.METHODS: Between 2008 and 2012, 5 patients with centrally located hepatocellular carcinoma invading or in the vicinity of the right and middle hepatic veins underwent extended central hepatectomy. The thick inferior right hepatic vein was preserved during dissection. Gore-Tex graft was used for segment 6 outflow reconstruction in the absence of the thick inferior right hepatic vein.RESULTS: The mean future remnant liver volume for segments 2 and 3 was 28% versus 45% on segment 6 preservation. The mean tumor diameter was 7.4 cm. The thick inferior right hepatic vein was found in 1 patient. Outflow reconstruction from segment 6 was performed in 4 patients. Postoperative complications included bile leakage (1 patient), pleural effusion (2) and liver failure (1). The rate of graft patency was 75%. There was no perioperative mortality.CONCLUSION: Extended central hepatectomy is a safe alternative for extended hepatic resection in selected patients attempting to preserve the functional liver parenchyma. | Mahmoud Abdelwahab Ali Jung-Fang Chuang Chee-Chien Yong Chih-Chi Wang Chi-Ying Lin Chao-Long Chen | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，1： | 9 |
| 8 | Endoscopic ultrasound-guided deep and large biopsy for diagnosis of gastric infiltrating tumors with negative malignant endoscopy biopsies显示文摘AIM: To assess the diagnostic yield and safety of adeep and large biopsy technique under the guidance of endoscopic ultrasound(EUS) for diagnosis of gastric infiltrating tumors with negative malignant endoscopy biopsies.METHODS: From January 2009 to March 2014, 36 patients in whom gastric infiltrating tumors had been diagnosed by EUS received negative results for malignancy after endoscopic biopsies. The deep and large biopsy technique combined bite-on-bite technique with or without endoscopic mucosal resection(EMR) to obtain submucosal tissue from lesions. EUS was used to select the appropriate biopsy sites. If the lesion protruded into the cavity, EMR was performed for removal of the overlying mucosa and then bite-onbite technique was conducted in the resected area to obtain submucosal tissue. If the lesion appeared to be flat or was difficult to lift by injection, the bite-on-bite technique was directly used.RESULTS: Twenty-eight of the 36 patients were treated by EMR followed by bite-on-bite technique, while 8 patients only underwent bite-on-bite technique. Histological results showed 23 of the 36 lesions were poorly differentiated adenocarcinomas, 2 diffuse large B cell lymphomas, 4 mucosa-associated lymphoid tissue-type lymphomas, and 7 undiagnosed. The deep and large biopsy technique provided a definitive and conclusive diagnosis in 29(80.6%) of the 36 patients. The 12 gastric linitis plastica and 6 lymphoma patients received chemotherapy and avoided surgery. Minor oozing of blood in 2 mucosal resection wounds was managed by argon plasma coagulation and in 5 cases after deep biopsies by epinephrine(0.001%). Neither severe hemorrhage nor perforation occurred in any patient.CONCLUSION: The deep and large biopsy technique is superior to ordinary endoscopic biopsy for achieving an accurate diagnosis of gastric infiltrating tumors.This procedure guided by EUS is an effective and safe diagnostic method for gastric infiltrating tumors in which endoscopic biopsy results were negative for malignancy. | Xin-Xin Zhou Hang-Hai Pan Ali Usman Feng Ji Xi Jin Wei-Xiang Zhong Hong-Tan Chen | 2015 | World Journal of Gastroenterology2015，21，12： | 9 |
| 9 | WAVE LOCALIZATION IN RANDOMLY DISORDERED PERIODIC PIEZOELECTRIC RODS显示文摘在周期、混乱的周期的压电的杆的波浪繁殖在这篇论文被学习。在二个连续单位房间之间的转移矩阵根据连续性条件被获得。压电的材料的机电的联合被考虑。根据矩阵特征值的理论,在周期的结构的频率乐队被学习。而且,由在两个介绍混乱尺寸更少长度和压电的陶艺的有弹性的常数,在混乱周期的结构的波浪本地化被使用矩阵特征值方法和 Lyapunov 代表方法也学习。调节了周期的结构,这被发现让频率通带和站乐队和本地化现象能发生在错误调子周期的结构。由于压电的效果,而且,为不能通过结构宣传的波浪的频率区域稍微随压电的常数的增加被增加。 | Li Fengming Wang Yuesheng Chen Ali | 2006 | Acta Mechanica Solida Sinica2006，19，1： | 9 |
| 10 | Chip-integrated plasmonic flat optics for mid-infrared full-Stokes polarization detection显示文摘Flat optics presents a new path to control the phase, amplitude, and polarization state of light with ultracompact devices. Here we demonstrate chip-integrated metasurface devices for polarization detection of mid-infrared light with arbitrary polarization states. Six high-performance microscale linear and circular polarization filters based on vertically stacked plasmonic metasurfaces(with total thickness <600 nm) are integrated on the same chip to obtain all four Stokes parameters of light with high accuracy. The device designs can be tailored to operate at any wavelength in the mid-infrared spectral region and are feasible for on-chip integration with mid-infrared(mid-IR) photodetectors and imager arrays. Our work will enable on-chip mid-IR polarimeters and polarimetric imaging systems, which are highly desirable for many applications, such as clinical diagnosis, target detection, and space exploration. | JING BAI CHU WANG XIAHUI CHEN ALI BASIRI CHAO WANG YU YAO | 2019 | Photonics Research2019，7，9： | 8 |
| 11 | ELASTIC WAVE LOCALIZATION IN TWO-DIMENSIONAL PHONONIC CRYSTALS WITH ONE-DIMENSIONAL QUASI-PERIODICITY AND RANDOM DISORDER显示文摘在里面飞机并且反飞机橡皮波浪宣传在的乐队结构二维订并且混乱(在一个方向) phononic 晶体在这份报纸被学习。波浪繁殖的本地化被介绍由 plane-wave-based 转移矩阵方法是计算的本地化因素的概念由于随机的混乱讨论。由以一个特殊方法从频率把伪频率当作偏差,在另外的方向在一个方向和翻译对称有伪频率(Fibonacci 顺序) 的二种伪 phononic 水晶被考虑,乐队结构被使用本地化因素描绘。结果证明本地化因素是在描绘二维的完美、随机混乱、伪周期的 phononic 晶体的乐队差距的一个有效参数。phononic 晶体的乐队结构能被不同随机的混乱调节或改变伪周期的参数。伪 phononic 晶体比的与更狭窄的宽度展出更多的乐队差距订并且随机混乱的系统。 | Ali Chen Yuesheng Wang Guilan Yu Yafang Guo Zhengdao Wang | 2008 | Acta Mechanica Solida Sinica2008，21，6： | 8 |
| 12 | Use of genotype-environment interactions to elucidate the pattern of maize root plasticity to nitrogen deficiency显示文摘Maize(Zea mays L.) root morphology exhibits a high degree of phenotypic plasticity to nitrogen(N) de ficiency,but the underlying genetic architecture remains to be investigated Using an advanced BC_4F_3 population,we investigated the root growth plasticity under two contrasted N levels and identi fied the quantitative trait loci(QTLs) with QTL-environment(Q×E)interaction effects. Principal components analysis(PCA) on changes of root traits to N de ficiency(D LN-HN) showed that root length and biomass contributed for 45.8% in the same magnitude and direction on the first PC,while root traits scattered highly on PC_2 and PC_3. Hierarchical cluster analysis on traits for D LN-HN further assigned the BC_4F_3 lines into six groups,in which the special phenotypic responses to N de ficiency was presented These results revealed the complicated root plasticity of maize in response to N de ficiency that can be caused by genotype environment(G×E) interactions. Furthermore,QTL mapping using a multi-environment analysis identi fied 35 QTLs for root traits. Nine of these QTLs exhibited signi ficant Q×E interaction effects. Taken together,our findings contribute to understanding the phenotypic and genotypic pattern of root plasticity to N de ficiency,which will be useful for developing maize tolerance cultivars to N de ficiency. | Pengcheng Li Zhongjuan Zhuang Hongguang Cai Shuai Cheng Ayaz Ali Soomro Zhigang Liu Riliang Gu Guohua Mi Lixing Yuan Fanjun Chen | 2016 | Journal of Integrative Plant Biology2016，58，3： | 8 |
| 13 | Convergent genomic signatures of high-altitude adaptation among domestic mammals显示文摘Abundant and diverse domestic mammals living on the Tibetan Plateau provide useful materials for investigating adaptive evolution and genetic convergence.Here,we used 327 genomes from horses,sheep,goats,cattle,pigs and dogs living at both high and low altitudes,including 73 genomes generated for this study,to disentangle the genetic mechanisms underlying local adaptation of domestic mammals.Although molecular convergence is comparatively rare at the DNA sequence level,we found convergent signature of positive selection at the gene level,particularly the EPAS1 gene in these Tibetan domestic mammals.We also reported a potential function in response to hypoxia for the gene C10 orf67,which underwent positive selection in three of the domestic mammals.Our data provide an insight into adaptive evolution of high-altitude domestic mammals,and should facilitate the search for additional novel genes involved in the hypoxia response pathway. | Dong-Dong Wu Cui-Ping Yang Ming-Shan Wang Kun-Zhe Dong Da-Wei Yan Zi-Qian Hao Song-Qing Fan Shu-Zhou Chu Qiu-Shuo Shen Li-Ping Jiang Yan Li Lin Zeng He-Qun Liu Hai-Bing Xie Yun-Fei Ma Xiao-Yan Kong Shu-Li Yang Xin-Xing Dong Ali Esmailizadeh David M Irwin Xiao Xiao Ming Li Yang Dong Wen Wang Peng Shi Hai-Peng Li Yue-Hui Ma Xiao Gou Yong-Bin Chen Ya-Ping Zhang | 2020 | National Science Review2020，7，6： | 7 |
| 14 | Mechanical behavior and failure mechanism of polyurea nanocomposites under quasi-static and dynamic compressive loading显示文摘Polyurea is an elastomeric material that can be applied to enhance the protection ability of structures under blast and impact loading.In order to study the compressive mechanical properties of SiC/polyurea nanocomposites under quasi-static and dynamic loading,a universal testing machine and split Hopkinson pressure bar(SHPB)apparatus were used respectively.The stress-strain curves were obtained on polyurea and its composites at strain rates of 0.001e8000 s1.The results of the experiment suggested that increase in the strain rates led to the rise of the flow stress,compressive strength,strain rate sensitivity and strain energy.This indicates that all of the presented materials were dependent on strain rate.Moreover,these mechanical characters were enhanced by incorporating a small amount of SiC into polyurea matrix.The relation between yield stress and strain rates were established using the power law functions.Finally,in order to investigate the fracture surfaces and inside information of failed specimens,scanning electron microscopy(SEM)and micro X-ray computed tomography(micro-CT)were used respectively.Multiple voids,crazes,micro-cracks and cracking were observed in fracture surfaces.On the other hand,the cracking propagation was found in the micro-CT slice images.It is essential to understand the deformation and failure mechanisms in all the polyurea materials. | Qiang Liu Peng-wan Chen Yan-song Guo Jian-jun Su Lu Han Ali Arab Jian-fei Yuan | 2021 | Defence Technology(防务技术)2021，17，2： | 7 |
| 15 | 1-MCP Regulates Ethanol Fermentation and GABA Shunt Pathway Involved in Kiwifruit Quality During Postharvest Storage显示文摘Kiwifruit(Actinidia deliciosa)‘Bruno’is prone to accumulate ethanol rapidly after respiratory climacteric during storage at ambient conditions without stresses,which causes quality deterioration of the fruit associated with alcohol off-flavor.For maintaining the postharvest quality of kiwifruit‘Bruno’,the effects of 1.0μL•L^−11-methylcyclopropene(1-MCP)treatment on regulating the ethanol fermentation andγ-aminobutyric acid(GABA)shunt pathway associated with control of alcohol off-flavor were investigated during storage at room temperature(24±1)°C for 27 days.The results showed that 1-MCP treatment significantly reduced the respiration rate,ethylene production,decay rate,ascorbic acid(AsA)loss,and delayed the decline in the firmness and titratable acidity(TA),and the increase in total soluble solid(TSS)in kiwifruit.Furthermore,1-MCP treatment effectively inhibited the increases in contents of acetaldehyde,ethanol,and GABA along with the suppressed activities of key enzymes involved in ethanol fermentation and GABA shunt pathway,such as pyruvate decarboxylase(PDC),alcohol dehydrogenase(ADH),glutamate decarboxylase(GAD),and GABA-transaminase(GABA-T)in kiwifruit during storage.In conclusion,1-MCP treatment efficiently regulated the ethanol fermentation and GABA shunt pathway by delaying the ripening process to avoid the alcohol off-flavor development,thereby contributed to maintaining the quality of the kiwifruit. | Maratab Ali Muhammad Ammar Raza Shenge Li Lichao Zhou Chen Huan Shen Shuling Xiaolin Zheng | 2021 | Horticultural Plant Journal2021，7，1： | 7 |
| 16 | 863 genomes reveal the origin and domestication of chicken显示文摘Despite the substantial role that chickens have played in human societies across the world,both the geographic and temporal origins of their domestication remain controversial.To address this issue,we analyzed 863 genomes from a worldwide sampling of chickens and representatives of all four species of wild jungle fowl and each of the five subspecies of red jungle fowl(RJF).Our study suggests that domestic chickens were initially derived from the RJF subspecies Gallus gallus spadiceus whose present-day distribution is predominantly in southwestern China,northern Thailand and Myanmar.Following their domestication,chickens were translocated across Southeast and South Asia where they interbred locally with both RJF subspecies and other jungle fowl species.In addition,our results show that the White Leghorn chicken breed possesses a mosaic of divergent ancestries inherited from other subspecies of RJF.Despite the strong episodic gene flow from geographically divergent lineages of jungle fowls,our analyses show that domestic chickens undergo genetic adaptations that underlie their unique behavioral,morphological and reproductive traits.Our study provides novel insights into the evolutionary history of domestic chickens and a valuable resource to facilitate ongoing genetic and functional investigations of the world's most numerous domestic animal. | Ming-Shan Wang Mukesh Thakur Min-Sheng Peng Yu Jiang Laurent Alain Francois Frantz Ming Li Jin-Jin Zhang Sheng Wang Joris Peters Newton Otieno Otecko Chatmongkon Suwannapoom Xing Guo Zhu-Qing Zheng Ali Esmailizadeh Nalini Yasoda Hirimuthugoda Hidayat Ashari Sri Suladari Moch Syamsul Arifin Zein Szilvia Kusza Saeed Sohrabi Hamed Kharrati-Koopaee Quan-Kuan Shen Lin Zeng Min-Min Yang Ya-Jiang Wu Xing-Yan Yang Xue-Mei Lu Xin-Zheng Jia Qing-Hua Nie Susan Joy Lamont Emiliano Lasagna Simone Ceccobelli Humpita Gamaralalage Thilini Nisanka Gunwardana Thilina Madusanka Senasige Shao-Hong Feng Jing-Fang Si Hao Zhang Jie-Qiong Jin Ming-Li Li Yan-Hu Liu Hong-Man Chen Cheng Ma Shan-Shan Dai Abul Kashem Fazlul Haque Bhuiyan Muhammad Sajjad Khan Gamamada Liyanage Lalanie Pradeepa Silva Thi-Thuy Le Okeyo Ally Mwai Mohamed Nawaz Mohamed Ibrahim Megan Supple Beth Shapiro Olivier Hanotte Guojie Zhang Greger Larson Jian-Lin Han Dong-Dong Wu Ya-Ping Zhang | 2020 | Cell Research2020，30，8： | 7 |
| 17 | 骨组织工程用可降解多孔含银镁基支架的合成及体外性能(英文)显示文摘感染是骨损伤临床治疗中常见的并发症。镁基复合材料是一种可生物降解的抗菌生物材料,已被用于减少术后感染。本文作者合成含银镁基骨组织工程支架材料,并对其进行体外表征。通过造孔剂法制备4种不同银含量(0、0.5、1、和2 wt.%)的多孔镁基支架,用Mg-Ca-Mn-Zn-xAg (MCMZ-xAg)表示,其中x表示银含量。研究银含量对材料的孔隙结构、力学性能、生物活性和抑菌区的影响。采用X射线衍射分析(XRD)、扫描电镜(SEM)、透射电镜(TEM)和荧光显微镜对支架进行表征。体外腐蚀试验结果表明,银含量低的支架比银含量高的支架具有更好的耐腐蚀性。抗菌活性的检测结果表明MCMZ-Ag支架具有显著抑制大肠杆菌和(E.coli)和金黄色葡萄球菌(S.aureus)生长的作用,且随着含银量的增加,MCMZ-Ag支架周围的抑菌区面积逐渐增加。然而,含银量过高会增加材料的细胞毒性。总之,含0.5wt.%Ag的支架因其具有连通的孔隙、足够的力学性能、抗菌活性和细胞黏附性能,在修复与替换受损和患病骨方面具有应用前景。 | Hamid Reza BAKHSHESHI-RAD Ehsan DAYAGHI Ahmad Fauzi ISMAIL Madzlan AZIZ Ali AKHAVAN-FARID Xiongbiao CHEN | 2019 | Transactions of Nonferrous Metals Society of China2019，29，5： | 6 |
| 18 | From Green Super Rice to green agriculture:Reaping the promise of functional genomics research显示文摘Producing sufficient food with finite resources to feed the growing global population while having a smaller impact on the environment has always been a great challenge.Here,we review the concept and practices of Green Super Rice(GSR)that have led to a paradigm shift in goals for crop genetic improvement and models of food production for promoting sustainable agriculture.The momentous achievements and global deliveries of GSR have been fueled by the integration of abundant genetic resources,functional gene discoveries,and innovative breeding techniques with precise gene and whole-genome selection and efficient agronomic management to promote resource-saving,environmentally friendly crop production systems.We also provide perspectives on new horizons in genomic breeding technologies geared toward delivering green and nutritious crop varieties to further enhance the development of green agricul-ture and better nourish the world population. | Sibin Yu Jauhar Ali Shaochuan Zhou Guangjun Ren Huaan Xie Jianlong Xu Xinqiao Yu Fasong Zhou Shaobing Peng Liangyong Ma Dingyang Yuan Zefu Li Dazhou Chen Ruifeng Zheng Zhigang Zhao Chengcai Chu Aiqing You Yu Wei Susong Zhu Qiongyao Gu Guangcun He Shigui Li Guifu Liu Changhua Liu Chaopu Zhang Jinghua Xiao Lijun Luo Zhikang Li Qifa Zhang | 2022 | Molecular Plant2022，15，1： | 6 |
| 19 | Numerical and experimental investigations of liquid mixing in two-stage micro-impinging stream reactors显示文摘A two-stage micro-impinging stream reactor(TS-MISR) that combined a first pre-mixing stage with a second micro-impinging stream reacting stage for continuous multi-component reacting systems has been built from commercial T-junctions and steel micro-capillaries. Both of operating parameters and reactor configurations,such as jet Reynolds number(Rej), volumetric flow ratio(R), the first-stage junction angle(φ), the connecting capillary length(Lc) and connecting capillary diameter(dc), had significant effects on the micromixing efficiency of the reactor. Such effects were investigated for both of the two stage structures, respectively, by experimental and CFD methods and were optimized for the best micromixing performance. Intensified micromixing among at least three reacting components can be achieved in a continuous mode by using TS-MISR; therefore, it is expected that the TS-MISR will produce products of higher quality with more uniform and stable element distribution. | Tianyu Guo Bin Ruan Zhiwei Liu Muhammad Ali Jamal Lixiong Wen Jianfeng Chen | 2017 | Chinese Journal of Chemical Engineering2017，25，4： | 6 |
| 20 | Comparison of machine learning methods for estimating permeability and porosity of oil reservoirs via petro-physical logs显示文摘This paper deals with the comparison of models for predicting porosity and permeability of oil reservoirs by coupling a machine learning concept and petrophysical logs.Different machine learning methods including conventional artificial neural network,genetic algorithm,fuzzy decision tree,the imperialist competitive algorithm(ICA),particle swarm optimization(PSO),and a hybrid of those ones are employed to have a comprehensive comparison.The machine learning approach was constructed and tested via data samples recorded from northern Persian Gulf oil reservoirs.The results gained from the machine learning models used in this paper are compared to the relevant real petrophysical data and the outputs achieved by other methods employed in our previous studies.The average relative absolute deviation between the approach estimations and the relevant actual data is found to be less than 1%for the hybridized approaches.The results reported in this paper indicate that implication of hybridized machine learning methods in porosity and permeability estimations can lead to the construction of more reliable static reservoir models in simulation plans. | Mohammad Ali Ahmadi Zhangxing Chen | 2019 | Petroleum2019，5，3： | 6 |
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