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| 1 | Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis显示文摘Polyreactive 天生类型的 B 房间说明在圆周表示自我反应的许多 B 房间。这些 B 房间的不适当的规定可以是位于自体免疫的疾病下面的一个重要因素。这里,我们在导致骨胶原的关节炎(中央情报局) 的开发探索了自我反应的天生的 B 房间的影响,风湿性关节炎的一个鼠标模型。我们显示出那个脾的边缘的地区(MZ ) ,然而并非 B-1 B 房间在 naı 展出自发的 IgM 反应到自体同源的骨胶原 II; ¨ ve 老鼠。在有在完全的 Freund’ 的 heterologous 骨胶原 II 的免疫之上;骨胶原反应的 MZ B 房间很快扩展了的 s 助手,当 B-1 B 房间显示出谦虚反骨胶原回答时。MZ B 房间被像使用费的受体(TLR ) 容易激活 4 并且在 vitro,导致的增长和 cytokine 分泌物的 9-ligands,暗示 B 房间受体和 TLR 的那个双约会可以把有免疫力的反应提升到自我抗原。而且,告知骨胶原的 MZ B 房间显示出在 vivo 在 IgG 反骨胶原抗体的 vitro 和正式就职由血缘的 T 房间增长思考了的重要介绍抗原的能力。在 1 和 2 表明了的补充受体是缺乏的 MZ B 房间增加了增长和 cytokine 生产,当时 Fcγ房间的受体 IIb 缺乏导致增加的 cytokine 生产和抗原表示。在结论,我们的数据在中央情报局作为自体免疫的反应的开始者加亮自我反应的 MZ B 房间,在补充和 Fc 受体在在房间控制自我反应是相关的的地方。 | Anna-Karin E Palm Heike C Friedrich Anja Mezger Maya Salomonsson Linda K Myers Sandra Kleinau | 2015 | Cellular & Molecular Immunology2015，12，4： | 3 |
| 2 | Highly sensitive immunoassay based on a monoclonal antibody specific for microcystins 显示文摘 | Anne Z Anja E Michael GW | 2001 | Analytica Chimica Acta2001，441，1： | 1 |
| 3 | Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle–mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response显示文摘 | Ivan Grskovic Anna Kutsch Christian Frie Gergely Groma Jacek Stermann Ursula Schl?tzer‐Schrehardt Anja Niehoff Stephen E Moss Sabrina Rosenbaum Ernst P?schl Markus Chmielewski Gunter Rappl Hinrich Abken John F Bateman Kathryn SE Cheah Mats Paulsson Bent B | 2012 | J Bone Miner Res2012，，11： | 1 |
| 4 | Kinetics of lipase-catalyzed esterifica- tion in organic media correct model and solvent effects on parameters 显示文摘 | Janssen Anja E M Sjursnes B J | 1999 | Engyme and Microbiol Technology1999，24，89： | 1 |
| 5 | Reproducibility of Immunohistochemical Scoring for Epidermal Growth Factor Receptor Expression in Non-Small Cell Lung Cancer: Round Robin Test显示文摘 | R?schoff Josef Kerr Keith M Grote Hans J Middel Peter von Heydebreck Anja Alves Ven?ncio A Baldus Stephan E B?ttner Reinhard Carvalho Lina Fink Ludger Jochum Wolfram Lo Anthony W I L?pez-R?os Fernando Marx Alexander Molina Thierry J Olszews | 2013 | Archives of Pathology & Laboratory Medicine2013，，9： | 1 |
| 6 | A new sensitive method for the quantification of glyoxal and methylglyoxal in snow and ice by stir bar sorptive ex- traction and liquid desorption-HPLC-ESI-MS 显示文摘 | CHRISTINA MT ANJA E MARGIT S | 2014 | Ana lytical and Bioanalytical Chemistry2014，，： | 1 |
| 7 | The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways显示文摘 | Anja N Sylke H Marcelo E | 2002 | Biol Chem2002，277，7： | 1 |
| 8 | Kinetics of lipase-catalyzed esterification in organic media:correct model and solvent effects on parameters显示文摘 | Janssen Anja E M Sjursnes B J Vakurov A V | 1999 | Engyme and Microbiol Technology1999，24，89： | 1 |
| 9 | A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease显示文摘 | Marcus Mühlbauer Anja K Bosserhoff Arndt Hartmann Wolfgang E Thasler Thomas S Weiss Hans Herfarth Guntram Lock Jürgen Sch?lmerich Claus Hellerbrand | 2003 | Gastroenterology2003，，4： | 1 |
| 10 | Interferon-y-primed monocytoid cell lines: optimizing their use for in vitro detection of bacterial pyrogens 显示文摘 | Anja P Simone E Thomas WJ | 2000 | Journal of Immunological Methods2000，233，12： | 1 |
| 11 | Interferon-primed monocytoid cell lines:Optimizing their use for in vitro detection of bacterial pyrogens显示文摘 | Anja P Simone E Thomas WJ | 2000 | J Immunol Methods2000，233，12： | 1 |
| 12 | Fluid therapy in septic shock显示文摘 | EMANUEL P R ANJA K J LAURA E W | 2010 | Curr Opin Crit Care2010，16，： | 1 |
| 13 | A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease显示文摘 | Marcus Mühlbauer Anja K Bosserhoff Arndt Hartmann Wolfgang E Thasler Thomas S Weiss Hans Herfarth Guntram Lock Jürgen Sch?lmerich Claus Hellerbrand | 2003 | Gastroenterology2003，，4： | 1 |
| 14 | Abdominal Actinomycosis: a Rare Complication after Laparoscopic Gastric Bypass显示文摘 | Sammy A. Baierlein Anja Wistop Christian Looser Thomas Peters Hans-Martin Riehle Markus Flüe Ralph Peterli | 2007 | Obesity Surgery2007，，8： | 1 |
| 15 | Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis 显示文摘 | Veronika Groh Anja Bruhl Hani E I-Gabalawy | 2003 | Proc Natl Acad Sci USA2003，5，： | 1 |
| 16 | Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial显示文摘 | Aimée HMM Arits Klara Mosterd Brigitte AB Essers Eefje Spoorenberg Anja Sommer Michette JM De Rooij Han PA van Pelt Patricia JF Quaedvlieg Gertruud AM Krekels Pierre AFA van Neer Joris J Rijzewijk Adrienne J van Geest Peter M Steijlen Patty J Nelemans Nic | 2013 | Lancet Oncology2013，，7： | 1 |
| 17 | More virological failure with lamivudine than emtricitabine in efavirenz and nevirapine regimens in the Dutch nationwide HIV Cohort显示文摘 | Anja F Johann E Schmitz G H | 2014 | J Int Aids Soc2014，17，19： | 1 |
| 18 | Interventions to reduce the stigma associated with severe mental illness : Experiences from the open the doors program in germany 显示文摘 | Wolfgang Gaebel Anja E Baumann MA Phil | 2003 | Can J Psychiatry2003，48，10： | 1 |
| 19 | Somatic aberrations of mismatch repair genes as a cause of microsatellite‐unstable cancers显示文摘 | Willemina RR Geurts‐Giele Celine HM Leenen Hendrikus J Dubbink Isabelle C Meijssen Edward Post Hein FBM Sleddens Ernst J Kuipers Anne Goverde Ans MW van den Ouweland Margot GF van Lier Ewout W Steyerberg Monique E van Leerdam Anja Wagner Winand NM Dinjens | 2014 | Pathol2014，，4： | 1 |
| 20 | The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP signaling pathways显示文摘 | Anja N Sylke H Marcelo E | 2002 | biol Chem2002，277，7： | 1 |
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