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| 1 | Hepatitis B vaccination in patients with inflammatory bowel disease显示文摘AIM:To determine the prevalence for hepatitis B virus(HBV) and HBV screening and vaccination practices for inflammatory bowel disease(IBD).METHODS:This study is a retrospective,cross-sectional observational study.A retrospective chart review was performed in 500 patients who have been consecutively treated for IBD between September 2008 and January 2013 at the Rush University Medical Center Gastroenterology section.The patients were identified through the electronic medical record with the criteria that they attended the gastroenterology clinic,and that they had a diagnosis of IBD at the time of visit discharge.Once identified,each record was analyzed to determine whether the subject had been infected with HBV in the past,already been vaccinated against HBV,or advised to get vaccinated and followed through with the recommended vaccination.RESULTS:About 254 out of 500 patients(51%) had HBV screening ordered.Among those ordered to have screening tests,86% followed through with HBV serology.Gastroenterology physicians had significantly different screening ratios from each other(P < 0.001).There were no significant differences in the ratios of HBV screening when IBD specialists were compared to other gastroenterology physicians(0.505 ± 0.023 vs 0.536 ± 0.066,P = 0.66).Of those 220 patients screened,51% of IBD patients were found not to be immune against HBV.Approximately 50% of gastroenterology physicians recommended HBV vaccinations to their patients in whom serology was negative for antibodies against HBV.IBD specialists recommended vaccinations to a higher percentage of their patients compared to other gastroenterology physicians(0.168 ± 0.019 vs 0.038 ± 0.026,P = 0.015).Present and/or past HBV infection was found in 3.6% of the patients who had serology checked.There was no statistically significant difference in the prevalence of hepatitis B surface antigen(HBsAg) between our study and that reported in previous studies done in Spain(4/220 vs 14/2076 respectively,P = 0.070); and in France(4/220 vs 3/315 respectively,P = 0.159).But,the prevalence of anti-HBcAb in this study was less than that reported in the study in Spain(7/220 vs 155/2076 respectively,P = 0.006); and was not sig-nificantly different from that reported in the study in France(7/220 vs 8/315 respectively,P = 0.313).CONCLUSION:The prevalence of HBsAg in our IBD patients was not higher than previously reported European studies.Most IBD patients are not routinely screened or vaccinated against HBV at a tertiary referral center in the United States. | Ruwaida Ben Musa Anuhya Gampa Sanjib Basu Ali Keshavarzian Garth Swanson Michael Brown Rana Abraham Keith Bruninga John Losurdo Mark DeMeo Sohrab Mobarhan David Shapiro Ece Mutlu | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 2 | The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection显示文摘 | Sheldon P Stone Ben S Cooper Chris C Kibbler Barry D Cookson Jenny A Roberts Graham F Medley Georgia Duckworth Rosalind Lai Shah Ebrahim Erwin M Brown Phil J Wiffen Peter G Davey | 2007 | The Lancet Infectious Diseases2007，，4： | 1 |
| 3 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 4 | NF- kappa B as an integrator of diverse signaling pathways: the heart of myocardial signaling? 显示文摘 | Jones WK Brown M Ben X | 2003 | Cardiovasc Toxicol2003，3，3： | 1 |
| 5 | Normophosphatemic familial tumoral calcinosis is caused by deleterious mutations in SAMD9,encoding a TNF-alpha responsive protein显示文摘 | Chefetz I Ben Amitai D Browning S | 2008 | J Invest Dermato2008，128，6： | 1 |
| 6 | Light Switching of Molecules on Surfaces 显示文摘 | WESLEY R BROWNE BEN L | 2009 | Annu Rev Phys Chem2009，，60： | 1 |
| 7 | Community Policing in Post-September 11America:A Comment on the Concept of Communityoriented Counterterrorism显示文摘 | Ben Brown | 2007 | Police Practice And Research2007，，3： | 1 |
| 8 | Baselines for land-use change in the tropics: application to avoided deforestation projects显示文摘 | Sandra Brown Myrna Hall Ken Andrasko Fernando Ruiz Walter Marzoli Gabriela Guerrero Omar Masera Aaron Dushku Ben DeJong Joseph Cornell | 2007 | Mitigation and Adaptation Strategies for Global Change2007，，6： | 1 |
| 9 | Phylogeography and historical demography of Polypedates leucomystax in the islands of Indonesia and the Philippines: Evidence for recent human-mediated range expansion?显示文摘 | Rafe M. Brown Charles W. Linkem Cameron D. Siler Jeet Sukumaran Jacob A. Esselstyn Arvin C. Diesmos Djoko T. Iskandar David Bickford Ben J. Evans Jimmy A. McGuire Lee Grismer Jatna Supriatna Noviar Andayani | 2010 | Molecular Phylogenetics and Evolution2010，，2： | 1 |
| 10 | Transcatheter Arterial Embolization with Only Particles for the Treatment of Unresectable Hepatocellular Carcinoma显示文摘 | Mary A. Maluccio Anne M. Covey Leah Ben Porat Joanna Schubert Lynn A. Brody Constantinos T. Sofocleous George I. Getrajdman William Jarnagin Ronald DeMatteo Leslie H. Blumgart Yuman Fong Karen T. Brown | 2008 | Journal of Vascular and Interventional Radiology2008，，6： | 1 |
| 11 | Normophosphatemic familial tumoral calcinosis is caused by deleterious mutations in SAMD9, encoding a TNF-alpha responsive protein 显示文摘 | Chefetz I Ben Amitai D Browning S | 2008 | J Invest Dermatol2008，128，6： | 1 |
| 12 | p38 Mitogen Activated Protein Kinase Mediates Both Death Signaling and Functional Depression in the Heart显示文摘 | Meijing Wang Ben M. Tsai Mark W. Turrentine Yousuf Mahomed John W. Brown Daniel R. Meldrum | 2005 | The Annals of Thoracic Surgery2005，，6： | 1 |
| 13 | Diagnosing rotavirus A associated IID: Using ELISA to identify a cut-off for real time RT-PCR显示文摘 | Gemma Phillips Ben Lopman Clarence C. Tam Miren Iturriza-Gomara David Brown Jim Gray | 2008 | Journal of Clinical Virology2008，，： | 1 |
| 14 | Robust Adaptive Vision for Robot Soccer显示文摘 | Gordon Wyeth Ben Brown | 2000 | Computer Science and Electrical Engineering University of Queensland Brisbane Australia2000，，： | 1 |
| 15 | Plant-driven fungal weathering:Early stages of mineral alteration at the nanometer scale显示文摘 | Bonneville S Smits M M Brown A Harrington J Leake J R Brydson R Benning L G | 2009 | Geology2009，37，7： | 1 |
| 16 | The Atacama Cosmology Telescope: cosmological parameters from three seasons of data显示文摘 | Jonathan L. Sievers Renée A. Hlozek Michael R. Nolta Viviana Acquaviva Graeme E. Addison Peter A. R. Ade Paula Aguirre Mandana Amiri John William Appel L. Felipe Barrientos Elia S. Battistelli Nick Battaglia J. Richard Bond Ben Brown Bryce Burger Erminia | 2013 | Journal of Cosmology and Astroparticle Physics2013，，10： | 1 |
| 17 | 我学会的重庆话显示文摘我1994年就来到了重庆,但没有留下,当时我是来做本科交涣生的,在西南大学待了三个月。那次让我记忆最深的事是中秋节,晚上我去了体育场,天已经黑了,只有月光。我霸到很多人部在操场上,慢慢地走走聊聊,时不时抬头行吞月亮。有一个人在操场对面吹长笛,合适的形容词应该是“悠扬”吧?那时的我只会拼音,要我现存来说的话,我会说“嘿舒服!” | Ben Brown | 2016 | 城市地理2016，0，8： | 0 |
| 18 | 温哥华公寓显示文摘温哥华公寓的建成预示着这个年轻的城市正在打开城市政策制定的新局面。它将成为从Granville大桥进入温哥华市中心的城市大门。塔楼和群房的设计是对新城市主义地域类型中的'温哥华主义'建筑的全新解读,配合一座纤细的塔楼,试图保留城市视觉通廊并激活步行通道。住宅塔楼借助高度和毗邻河流的地理位置,是唯一可以同时享受水景和山景的建筑,坐拥温哥华广袤的自然风光。 | Carl McDonald Melissa Bauld Aaron Mark Alan Tansey Alex Wu Alexandra Gustafsson Alina Tamosiunaite Amina Blacksher Aran Coakley Arash Adel Ahmadian Armen Menendian Barbora Srpkova Ben Zunkeler Benjamin Caldwell Benjamin Novacinski Bennett Gale Birk Daugaard Blake Theodore Smith Brian Foster Brian Rome Carolien Schippers Christopher James Malcolm Jr. Christopher Junkin Christopher Tron David Brown David Dottelonde Deborah Campbell Doug Stechschulte Douglass Alligood Edward Yung Elena Bresciani Filip Milovanovic Francesca Portesine Gabriel Hernandez Solano Gabriel Jewell-Vitale Hector Garcia Ivy Hume Jan Leenknegt Janice Rim John Kim Josiah Poland Julian Liang Julianne Gola Julie Kaufman Karol Bogdan Borkowski Kurt Nieminen Lauren Turner Lorenz Krisai Lucio Santos Marcella Martinez Martin Voelkle Matthew Dlugosz Megan Ng Michael Robert Taylor Otilia Pupezeanu Paula Domka Phillip MacDougall Ryan Yang Sean Franklin Sebastian Grogaard Simon Scheller Spencer Hayden Taylor Fulton Terrence Chew Terry Lallak Thomas Smith Tianqi Zhang Tobias Hjortdal Tran Le Valentina Mele Xinyu Wang Yaziel Juarbe Yoanna Shivarova Zach Walters Zhifei Xu Andrew Latreille Glotman Simpson Urban YVR 运小红(译) | 2019 | 城市环境设计2019，0，2： | 0 |
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