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| 1 | Endoscopic management of esophageal stenosis in children:New and traditional treatments显示文摘Post-esophageal atresia anastomotic strictures and postcorrosive esophagitis are the most frequent types of cicatricial esophageal stricture. Congenital esophageal stenosis has been reported to be a rare but typical disease in children; other pediatric conditions are peptic, eosinophilic esophagitis and dystrophic recessive epidermolysis bullosa strictures. The conservative treatment of esophageal stenosis and strictures(ES) rather than surgery is a well-known strategy for children. Before planning esophageal dilation, the esophageal morphology should be assessed in detail for its length, aspect, number and level, and different conservative strategies should be chosen accordingly. Endoscopic dilators and techniques that involve different adjuvant treatment strategies have been reported and depend on the stricture's etiology, the availability of different tools and the operator's experience and preferences. Balloon and semirigid dilators are the most frequently used tools. No high-quality studies have reported on the differences in the efficacies and rates of complications associated with these two types of dilators. There is no consensus in the literature regarding the frequency of dilations or the diameter that should be achieved. The use of adjuvant treatments has been reported in cases of recalcitrant stenosis or strictures with evidence of dysphagic symptoms. Corticosteroids(either systemically or locally injected), the local application of mitomycin C, diathermy and laser ES sectioning have been reported. Some authors have suggested that stenting can reduce both the number of dilations and the treatment length. In many cases, this strategy is effective when either metallic or plastic stents are utilized. Treatment complications, such esophageal perforations, can be conservatively managed, considering surgery only in cases with severe pleural cavity involvement. In cases of stricture relapse,even if such relapses occur following the execution of well-conducted conservative strategies, surgical stricture resection and anastomosis or esophageal substitution are the only remaining options. | Luigi Dall rsquo Oglio Tamara Caldaro Francesca Foschia Simona Faraci Giovanni Federici di Abriola Francesca Rea Erminia Romeo Filippo Torroni Giulia Angelino Paola De Angelis | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，4： | 16 |
| 2 | Patients with primary biliary cirrhosis have increased serum total antioxidant capacity measured with the crocin bleaching assay显示文摘AIM: The balance between oxidants and antioxidants can play an important role in the initiation and development of liver diseases. Recently, we have described a new automated method for the determination of total antioxidant capacity (TAC) in human serum and plasma.METHODS: We measured TAC and corrected TAC (CTAC -abstraction of interactions due to endogenous uric acid,bilirubin and albumin) in 52 patients with chronic liver diseases (41 patients with primary biliary cirrhosis (PBC),10 patients with chronic hepatitis C and 13 patients with viral HCV cirrhosis) as well as in 10 healthy controls. In 23 PBC patients measurement were also done 6 mo after treatment with ursodeoxycholic acid (UDCA). The TAC assay was based on a modification of the crocin bleaching assay. The results were correlated with routine laboratory measurements and the histological stage of PBC.RESULTS: There were no significant differences in TAC between the various groups. However, CTAC was considerably increased in the PBC group compared to controls and cirrhotics. Analysis of these patients according to disease stages showed that this increase was an early phenomenon observed only in stages Ⅰ and Ⅱ compared to controls, cirrhotics and patients with chronic hepatitis C).After 6 mo of treatment with UDCA, levels of CTAC decreased to those similar to that of controls.CONCLUSION: Patients in the early stages of PBC present with high levels of corrected total antioxidant capacity and this maybe related to the pathophysiology of the disease. UDCA treatment restores the levels of CTAC to control levels. | George Notas Niki Miliaraki Marilena Kampa Fillipos Dimoulios Erminia Matrella Adam Hatzidakis Elias Castanas Elias Kouroumalis | 2005 | World Journal of Gastroenterology2005，11，27： | 13 |
| 3 | Bariatric surgery and long-term nutritional issues显示文摘Bariatric surgery is recognized as a highly effective therapy for obesity since it accomplishes sustained weight loss, reduction of obesity-related comorbidities and mortality, and improvement of quality of life. Overall, bariatric surgery is associated with a 42% reduction of the cardiovascular risk and 30% reduction of all-cause mortality. This review focuses on some nutritional consequences that can occur in bariatric patients that could potentially hinder the clinical benefits of this therapeutic option. All bariatric procedures, to variable degrees, alter the anatomy and physiology of the gastrointestinal tract; this alteration makes these patients more susceptible to developing nutritional complications, namely, deficiencies of macro-and micro-nutrients, which could lead to disabling diseases such as anemia, osteoporosis, protein malnutrition. Of note is the evidence that most obese patients present a number of nutritional deficits already prior to surgery, the most important being vitamin D and iron deficiencies. This finding prompts the need for a complete nutritional assessment and, eventually, an adequate correction of pre-existing deficits before surgery. Another critical issue that follows bariatric surgery is post-operative weight regain, which is commonly associated with the relapse of obesity-related comorbidities. Nu-tritional complications associated with bariatric surgery can be prevented by life-long nutritional monitoring with the administration of multivitamins and mineral supplements according to the patient's needs. | Roberta Lupoli Erminia Lembo Gennaro Saldalamacchia Claudia Kesia Avola Luigi Angrisani Brunella Capaldo | 2017 | World Journal of Diabetes2017，8，11： | 8 |
| 4 | Clinical outcomes of compensated and decompensated cirrhosis: A long term study显示文摘AIM: To study these characteristics and prognostic patterns in a Greek patient population.METHODS: We analyzed a large cohort of cirrhotic patients referred to the department of Gastroenterology and Hepatology and the outpatient clinics of this tertiary hospital, between 1991 and 2008. We included patients with established cirrhosis, either compensated or decompensated, and further decompensation episodes were registered. A data base was maintained and updated prospectively throughout the study period.We analyzed differences in cirrhosis aetiology, time to and mode of decompensation, hepatocellular carcinoma(HCC) occurrence and ultimately patient survival.RESULTS: Five hundreds and twenty-two patients with median age 67(range, 29-91) years and average follow up 9 years-10 mo(range, 1-206 mo) were studied. Commonest aetiology was hepatitis C virus(HCV, 41%) followed by alcohol(31%). The median survival time in compensated cirrhotics was 115 mo(95%CI: 95-133), whereas in decompensated patients was 55 mo(95%CI: 36-75). HCV patients survived longer while HBV patients had over twice the risk of death of HCV patients. The median time to decompensation was 65 mo(95%CI: 51-79), with alcoholics having the highest risk(RR = 2.1 vs HCV patients). Hepatitis B virus(HBV) patients had the highest risk of HCC, alcoholics the lowest. Leading causes of death: liver failure, hepatorenal syndrome, sepsis and HCC progression. CONCLUSION: Cirrhosis aetiology and decompensation at presentation were predictors of survival. Alcoholics had the highest decompensation risk, HBV cirrhotics the highest risk of HCC and HCV cirrhotics the highest decompensation-free time. | Dimitrios N Samonakis Mairi Koulentaki Constantina Coucoutsi Aikaterini Augoustaki Chryssavgi Baritaki Emmanuel Digenakis Nikolaos Papiamonis Maria Fragaki Erminia Matrella Elias A Kouroumalis Maria Tzardi | 2014 | World Journal of Hepatology2014，6，7： | 4 |
| 5 | Diagnostic yield of EUS-FNA of small(≤15 mm) solid pancreatic lesions using a 25-gauge needle显示文摘Background: Early detection of small solid pancreatic lesions is increasingly common. To date, few and contradictory data have been published about the relationship between lesion size and endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) diagnostic yield. The aim of this study was to assess the relation between the size of solid pancreatic lesions and the diagnostic yield of EUS-FNA using a 25-gauge needle in a center without available rapid on-site evaluation.Methods: In the retrospective cohort study, we selected patients who underwent EUS-FNA for solid pancreatic lesions with a 25-gauge needle from October 2014 to October 2015. Patients were divided into three groups(≤15 mm, 16–25 mm and >25 mm), and the outcomes were compared.Results: We analyzed 163 patients. Overall adequacy, sensitivity, specificity and accuracy were 85.2%,81.8%, 93.7%, and 80.4%, respectively. When stratified by size, the sensitivity and accuracy correlated with size(P = 0.016 and P = 0.042, respectively). Multivariate analysis showed that lesion size was the only independent factor(P = 0.019, OR = 4.76) affecting accuracy. The role of size as an independent factor affecting accuracy was confirmed in a separate multivariate analysis, where size was included in the model as a covariate(P = 0.018, OR = 1.08).Conclusion: Our study demonstrates that, in the absence of rapid on-site evaluation, mass size affects the accuracy of EUS-FNA of solid pancreatic lesions. | Stefano Francesco Crinò Maria Cristina Conti Bellocchi Laura Bernardoni Erminia Manfrin Alice Parisi Antonio Amodio Nicolò De Pretis Luca Frulloni Armando Gabbrielli | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，1： | 4 |
| 6 | 在胰腺的 pseudocyst 的管理的 Miniprobe EUS显示文摘 Pancreatic pseudocysts(PP) arise from trauma and pancreatitis;endoscopic gastro-cyst drainage(EGCD) under endoscopic ultrasonography(EUS) in symptomatic PP is the treatment of choice.Miniprobe EUS(MEUS) allows EGCD in children.We report our experience on MEUS-EGCD in PP,reviewing 13 patients(12 children;male:female = 9:3;mean age:10 years,4 mo;one 27 years,malnourished male Belardinelli-syndrome;PP:10 post-pancreatitis,3 post-traumatic).All patients underwent ultrasonography,computed tomography and magnetic resonance imaging.Conservative treatment was the first option.MEUS EGCD was indicated for retrogastric cysts larger than 5 cm,diameter increase,symptoms or infection.EGCD(stent and/or nasogastrocystic tube) was performed after MEUS(20-MHz-miniprobe) identification of place for diathermy puncture and wire insertion.In 8 cases(61.5%),there was PP disappearance;one,surgical duodenotomy and marsupialization of retro-duodenal PP.In 4 cases(31%),there was successful MEUS-EGCD;stent removal after 3 mo.No complications and no PP relapse in 4 years of mean followup.MEUS EGCD represents an option for PP,allowing a safe and effective procedure. | Paola De Angelis Erminia Romeo Francesca Rea Filippo Torroni Tamara Caldaro Giovanni Federici di Abriola Francesca Foschia Claudia Caloisi Vincenzina Lucidi Luigi Dall’Oglio | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 3 |
| 7 | Incidence of cancer in the course of chronic pancreatitis显示文摘 | Giorgio Talamini Massimo Falconi Claudio Bassi Nora Sartori Roberto Salvia Erminia Caldiron Luca Frulloni Vincenzo Di Francesco Bruna Vaona Paolo Bovo Italo Vantini Paolo Pederzoli Giorgio Cavallini | 1999 | The American Journal of Gastroenterology1999，，5： | 2 |
| 8 | Cosmic Microwave Weak lensing data as a test for the dark universe显示文摘 | Erminia Calabrese Anise Slosar Alossandro Melchiorri | 2008 | arXiv: astro - ph/08032309vl 17 Mar 20082008，，08： | 1 |
| 9 | Strictureplasty and intestinal resection: different options in complicated pediatric-onset Crohn disease显示文摘 | Erminia Romeo Vincenzo Jasonni Tamara Caldaro Arrigo Barabino Girolamo Mattioli Stefania Vignola Giovanni Federici di Abriola Paola De Angelis Alessandro Pane Filippo Torroni Francesca Rea Luigi Dall’Oglio | 2012 | Journal of Pediatric Surgery2012，，5： | 1 |
| 10 | A one-dimesional numerical study of the salt diffusion in a salinity-gradient solar pond 显示文摘 | Celestino Angeli Erminia Leonardi | 2004 | Heat and Mass Transfer2004，47，： | 1 |
| 11 | Sperm vacuoles negatively affect outcomes in intracytoplasmic morphologically selected sperm injection in terms of pregnancy, implantation, and live-birth rates显示文摘 | Ermanno Greco Filomena Scarselli Gemma Fabozzi Alessandro Colasante Daniela Zavaglia Erminia Alviggi Katarzyna Litwicka Maria Teresa Varricchio Maria Giulia Minasi Jan Tesarik | 2013 | Fertility and Sterility2013，，： | 1 |
| 12 | Emergence of linezolid resistance in the vancomycin-resistant Enterococcus faecium multilocus sequence typing c l epidemic lineage显示文摘 | Maria G B Maurizio S Erminia S | 2006 | Antimicrob Chemother2006，44，3： | 1 |
| 13 | Custom dynamic stent for esophageal strictures in children显示文摘 | Francesca Foschia Paola De Angelis Filippo Torroni Erminia Romeo Tamara Caldaro Giovanni Federici di Abriola Alessandro Pane Maria Stella Fiorenza Francesco De Peppo Luigi Dall’Oglio | 2011 | Journal of Pediatric Surgery2011，，5： | 1 |
| 14 | Cancer size,histotype,and cellular grade may limit the success of fine-needle aspiration cytology for screen-detected nreast carcinoma显示文摘 | Erminia M Francesca F Andrea R | 2011 | Cancer2011，117，6： | 1 |
| 15 | Comparison of Platelet-Rich Plasma Formulations for Cartilage Healing: An in Vitro Study 显示文摘 | Carola C Giuseppe F Erminia M | 2014 | J Bone Joint Surg Am2014，96，5： | 1 |
| 16 | Vandetanib and Indwelling Pleural Catheter for Non–Small-Cell Lung Cancer With Recurrent Malignant Pleural Effusion显示文摘 | Erminia Massarelli Amir Onn Edith M. Marom Christine M. Alden Diane D. Liu Hai T. Tran Barbara Mino Ignacio I. Wistuba Saadia A. Faiz Lara Bashoura George A. Eapen Rodolfo C. Morice J. Jack Lee Waun K. Hong Roy S. Herbst Carlos A. Jimenez | 2014 | Clinical Lung Cancer2014，，： | 1 |
| 17 | Role of endoscopic retrograde cholangiopancreatography in diagnosis and management of congenital choledochal cysts: 28 pediatric cases显示文摘 | Paola De Angelis Francesca Foschia Erminia Romeo Tamara Caldaro Francesca Rea Giovanni Federici di Abriola Romina Caccamo Maria Rita Santi Filippo Torroni Lidia Monti Luigi Dall'Oglio | 2012 | Journal of Pediatric Surgery2012，，5： | 1 |
| 18 | Apparent Renal Cell Carcinomas in Tuberous Sclerosis Are Heterogeneous: The Identification of Malignant Epithelioid Angiomyolipoma显示文摘 | Maurizio Pea Franco Bonetti Guido Martignoni Elizabeth Petri Henske Erminia Manfrin Chiara Colato Jay Bernstein | 1998 | The American Journal of Surgical Pathology1998，，2： | 1 |
| 19 | Environmental Pollution Risk and Insurance显示文摘 | Vito Fragnelli Maria Erminia Marina | 2002 | Economic Theory and Applications2002，01，05： | 1 |
| 20 | A nu-merical code for the calculation for solar power in a cen-tral receiver system 显示文摘 | ERMINIA LEONARDI BRUNO D AGUANNO | 2011 | Energy2011，4，： | 1 |
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