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| 1 | Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘 | Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang | 2012 | Cellular & Molecular Immunology2012，9，3： | 18 |
| 2 | Different roles of galectin-9 isoforms in modulating E-selectin expression and adhesion function in LoVo colon carcinoma cells显示文摘 | Feng Zhang Minhua Zheng Ying Qu Jianfang Li Jun Ji Bo Feng Aiguo Lu Jianwen Li Mingliang Wang Bingya Liu | 2009 | Molecular Biology Reports2009，，5： | 1 |
| 3 | A convenient spectrometric assay system for intracellular quantitative measurement of DNA glycosylase activity显示文摘Cytosine methylation 是一个重要生物学事件。然而,它也由于由自发的水解作用的 5-methylcytosine 的 deamination 是 genomic 不稳定性的来源,它生产胸腺嘧啶并且导致 G : T 失配。胸腺嘧啶 DNA glycosylase 和 methyl-CpG-binding 蛋白质 4 是涉及失配修理进步的主要 DNA glycosylases,并且他们的活动在许多相关研究被测量了。在这研究,我们为细胞内部的 DNA glycosylase 活动的特定、量的测量开发了一个方便度谱的试金系统。G : T 失配被介绍进萤火虫的在上游的区域在 pGL3 控制 plasmid 的编码酶的顺序。仅当 G : T 失配被修理到 G : C,酶将在 transfected 房间被表示。由测量酶活动,它简单、方便,细胞内部的 DNA glycosylase 活动能是坚定的。 | Shiying Li Qilai Huang Lu Wang Yan Lan Xin Zhang Bingya Yang Pan Du Zichun Hua | 2010 | Acta Biochimica et Biophysica Sinica2010，，6： | 1 |
| 4 | Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK显示文摘 | Ming Wang Chenglong Li Hui Nie Xin Lv Ying Qu Beiqin Yu Liping Su Jianfang Li Xuehua Chen Jingfang Ju Yingyan Yu Min Yan Qinlong Gu Zhenggang Zhu Bingya Liu | 2012 | FEBS Letters2012，，16： | 1 |
| 5 | Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK显示文摘 | Ming Wang Chenglong Li Hui Nie Xin Lv Ying Qu Beiqin Yu Liping Su Jianfang Li Xuehua Chen Jingfang Ju Yingyan Yu Min Yan Qinlong Gu Zhenggang Zhu Bingya Liu | 2012 | FEBS Letters2012，，16： | 1 |
| 6 | Revealing HOC1 burst from endoplasmic reticulum in cisplatin-treated cells via a ratiometric fluorescent probe显示文摘The reactive oxygen species(ROS) are tightly associated with endoplasmic reticulum(ER) stress.Thus,the deep and visual insight of aberrant ROS fluctuations in the ER can help us better investigate the ER stress-associated pathology.In this work,a fluorescent probe ERC for HOCI detection in the ER based on phenothiazine-derived coumarin platform was developed.In the presence of HOCI,ERC exhibited an emission change from 609 nm to 503 nm within seconds.It also showed high sensitivity(0.44 μmol/L)and superb photostability.Significantly,ERC displayed low cytotoxicity,good cell membrane permeability,and appreciable ER-targetability.Ultimately,the probe was successfully utilized to image exogenous and endogenous HOCl in living cells and reveal the HOCI burst in cisplatin-treated cancer cells. | Shan Wang Beitong Zhu Bingya Wang Xinhua Cao Lei Zhu Ji-Ting Hou Lintao Zeng | 2021 | Chinese Chemical Letters2021，32，5： | 1 |
| 7 | Discovery and genetic characterization of intestinal metaplasia in the Helicobacter felis-infected mouse model of gastric cancer显示文摘Gastric adenocarcinoma(GA)remains a leading cause of cancer-related deaths in the world [1].Of the different types of GA,intestinal-type GA is especially a major world-wide concern not only because this type of GA accounts for a large proportion of the global incidences but also because it is believed to be acquired,and thus possibly preventable.In particular,Helicobacter pylori-induced chronic inflammation is suggested to lead to the transformation of normal gastric mucosa to chronic gastritis,gastric atrophy,intestinal metaplasia(IM),dysplasia,and finally intestinal-type GA,as first proposed by Correa [2].Thus,IM tissue,characterized by the presence of cells resembling those derived from the intestine-specific lineage such as goblet cells that are not present in the normal stomach,is considered to be a critical precancerous tissue en route to GA [3].Furthermore,the transition to IM is believed to be the ‘point of no return’since the IM tissue does not revert back to normal gastric tissue after the eradication of H.pylori [4].However,the precise details of the IM tissue that are critical to the subsequent development of GA are not presently understood. | Jiangrong Chen Chunchao Zhu Chaojie Wang Xiaodan Zhang Jian Ni Daniel M.Czajkowsky Bingya Liu Yan Guo | 2019 | Acta Biochimica et Biophysica Sinica2019，51，2： | 1 |
| 8 | MiR-199a-3p promotes gastric cancer progression by targeting ZHX1显示文摘 | Zhenqiang Wang Xingjie Ma Qiang Cai Xinjing Wang Beiqin Yu Qu Cai Bingya liu Zhenggang Zhu Chen Li | 2014 | FEBS Letters2014，，： | 1 |
| 9 | A Long-wavelength Emissive Phenothiazine Derived Fluorescent Probe for Detecting HOCI Upregulation in 5-FU Stimulated Living Cells显示文摘The endogenous hypochlorous acid(HOCI) has been evidenced in a variety of cellular courses. However, the role of HOCI in most pathophysiological processes still keeps unclear because of the limited detecting tools. In this work, we presented the pre- paration of a phenothiazine-derived fluorescent probe CIO-1 for HOCI detection with a cyanopyridinium moiety to improve its water solubility and lengthen its emission wavelength. The HOCI-promoted oxidation of sulfur atom in the probe resulted in a 460-fold emission intensity enhancement at 635 nm with high selectivity and sensitivity(detection limit: 1.12 nmol/L). The rapid response(5 s) also endowed the probe with real-time detection ability. Successfully, CIO-1 was devoted to the bioimaging of endogenous HOCI in inflamed RAW 264.7 cells and 5-fluorouracil-treated MCF-7 cells. | WANG Bingya GUO Xiaomei LIU Zuodong WU Yongquan HOU Ji-Ting | 2022 | Chemical Research in Chinese Universities2022，38，2： | 0 |
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