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| 1 | The Salt Overly Sensitive (SOS) Pathway: Established and Emerging Roles显示文摘土壤咸度与在农田的特殊关联在全世界是一个成长问题。察觉到并且对环境刺激作出回应的能力在使植物能幸存的最基本的过程之中。在细胞的水平,盐过分敏感(求救) 表明包括 SOS3, SOS2,和 SOS1 的小径被建议了在盐应力下面的细胞的发信号调停,维持离子动态平衡。不太众所周知是细胞地异质的器官怎么联合盐信号到细胞并且到全部器官和植物的适当生长的不同类型的动态平衡维护。最近的证据强烈显示不同规章的机制被根和射击响应盐应力采用。几份报告声明了在根, SOS 蛋白质可以在钠动态平衡除了他们的功能有新奇角色。SOS3 在温和的盐条件下面在根通过植物生长素坡度和最大值的调整在侧面的根的塑料开发起一个关键作用。求救蛋白质也在应力下面在细胞骨架的动力学起一个作用。这些结果暗示涉及对咸度的植物反应的规章的网络的高复杂性。这评论集中于发信号的 SOS 和求救蛋白质功能的新兴的复杂性,并且加亮 SOS 蛋白质怎么贡献不同回答除离子动态平衡以外腌应力的最近的理解。 | Hongtao Ji José M. Pardo Giorgia Batelli Michael J. Van Oosten Ray A. Bressan Xia Li | 2013 | Molecular Plant2013，6，2： | 22 |
| 2 | Partially defatted black soldier fly larva meal inclusion in piglet diets: effects on the growth performance, nutrient digestibility,blood profile, gut morphology and histological features显示文摘Background:The aim of this trial was to investigate the effects of different inclusion levels of a partially defatted black soldier fly (BSF,Hermetia illucens L.) larva meal on the growth performance,nutrient digestibility,blood profile,gut morphology and histological features of piglets.A total of 48 newly weaned piglets were individually weighed (initial body weight (IBW):6.1 ± 0.16 kg) and randomly allocated to 3 dietary treatments (4 boxes as replicates/treatment and 4 animals/box).BSF larva meal was included at increasing levels (0% [BSF0],5% [BSFS] and 10% [BSF10]) in isonitrogenous and isoenergetic diets formulated for two feeding phases:Ⅰ (from d 1 to d 23) and Ⅱ (from d 24 to d 61).The weight gain (WG),average daily gain (ADG),average daily feed intake (ADFI) and feed conversion ratio (FCR) were calculated for each feeding phase and for the whole trial.The haematochemical parameters and nutrient digestibility of the piglets were also evaluated.A total of 3 piglets per box were slaughtered on d 61 and the slaughtered piglets were submitted to morphometric investigations and histopathological examinations.Results:No overall significant differences were observed for growth performance (P > 0.05),except for the ADFI of phase Ⅱ,which showed a linear response to increasing BSF meal levels (P < 0.05,maximum for the BSF10 group).Dietary BSF meal inclusion did not significantly influence the blood profile,except as far as monocytes and neutrophils are concerned,and these showed a linear and quadratic response,respectively,to increasing BSF meal levels (P < 0.05,maximum for the BSF10 and BSF5 groups,respectively).On the other hand,the nutrient digestibility,gut morphology and histological features were not affected by dietary BSF meal inclusion (P > 0.05).Conclusions:The obtained results show that a partially defatted BSF larva meal can be used as a feed ingredient in diets for weaned piglets without negatively affecting their growth performance,nutrient digestibility,blood profile,gut morphology or histological features. | Ilaria Biasato Manuela Renna Francesco Gai Sihem Dabbou Marco Meneguz Giovanni Perona Silvia Martinez Ana Cristina Barroeta Lajusticia Stefania Bergagna Luca Sardi Maria Teresa Capucchio Enrico Bressan Andrea Dama Achille Schiavone Laura Gasco | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 19 |
| 3 | The Phosphate Transporter PHT4;6 Is a Determinant of Salt Tolerance that Is Localized to the Golgi Apparatus of Arabidopsis显示文摘破坏 PHT4 的功能的插入变化;(At5g44370 ) 6 引起 NaCl 被主要的根的减少的生长根尖端描绘,提高的侧面的分叉,并且胀大的 Arabidopsis 幼苗的超敏性。变异的显型被蔗糖,然而并非由甘露糖醇的 equiosmolar 集中加重,并且在媒介由低无机的磷酸盐稀释了。蛋白质 PHT4; 6 属于分享重要顺序类似到哺乳动物的类型的 permeases 的主要 Facilitator 总科 -- 我 Pi transporters 和小囊的 glutamate transporters,并且是植物的通常认为的细胞内部的磷酸盐 transporters 的 PHT4 家庭的一个成员。PHT4; 6 本地化那 PHT4 到膜和运输研究显示的 Golgi; 6 便于 Pi 然而并非氯化物或无机的阴离子的选择运输。有显示根胀大的另外的异种的 Phenotypic 类似建议那 PHT4;在蛋白质 N-glycosylation 和房间的 6 可能的功能围生合成,它为盐忍耐是必要的。一起,我们的结果显示那 PHT4;从为再循环免除 glycosylation 的 Pi 的 Golgi lumenal 空间的 6 运输 Pi 处理。 | Beatriz Cubero Yuko Nakagawa Xing-Yu Jiang Ken-Ji Miura Fang Li Kashchandra G. Raghothama Ray A. Bressan Paul M. Hasegawa Jose M. Pardo | 2009 | Molecular Plant2009，2，3： | 15 |
| 4 | Overexpression of Arabidopsis YUCCA6 in Potato Results in High-Auxin Developmental Phenotypes and Enhanced Resistance to Water Deficit显示文摘Indole-3-acetic 酸(IAA ) ,主要植物植物生长素,在色氨酸依赖者和色氨酸无关的小径被生产。在 Arabidopsis thaliana 的一条主要小径从色氨酸在二反应产生 IAA。步骤一由把国际语音学协会变换成丝兰属植物蛋白质催化的 IAA 的一个限制率的步骤跟随的色氨酸 aminotransferases 把色氨酸变换成 indole-3-pyruvic 酸(国际语音学协会) 。我们识别了推出了氨基酸序列的基因分享的八通常认为的 StYUC (茄属 tuberosum 丝兰属植物) Arabidopsis 丝兰属植物蛋白质的有那些的 50%70% 身份。都包括正规、保存丝兰属植物序列:FATGY 主题, FMO 签名顺序和 NADP 有约束力的序列。另外,五基因与 ~ 被发现 50% 氨基酸顺序身份到 Arabidopsis 色氨酸 aminotransferases。转基因的土豆(茄属 tuberosum cv。Jowon ) 组成地, overexpressing Arabidopsis AtYUC6 显示了象狭窄的向下卷的叶子,增加的高度,直立的身高,和长寿那样的高植物生长素的显型。转基因的土豆植物 overexpressing AtYUC6 基于减少的水损失显示出提高的干旱忍耐。显型在叶子与反应的氧种类的减少的层次被相关。结果在可以被利用改变植物回答到环境的土豆建议植物生长素生合成的一条功能的丝兰属植物小径。 | Jeong Im Kim Dongwon Baek Hyeong Cheol Park Hyun Jin Chun Dong-Ha Oh Min Kyung Lee Joon-Yung Cha Woe-Yeon Kim Min Chul Kim Woo Sik Chung Hans J. Bohner Sang Yeol Lee Ray A. Bressan Shin-Woo Lee Dae-Jin Yun | 2013 | Molecular Plant2013，6，2： | 15 |
| 5 | Abiotic Stress Tolerance: From Gene Discovery in Model Organisms to Crop Improvement显示文摘生产、持续的农业与象新鲜的水那样的宝贵资源的更少的输入在非最优的环境要求成长植物。为更好的理解和不能生活的压力忍耐的快速的改进,在遗传上易控制的模型有机体连接生理、生物化学的工作到分子的研究是重要的。与为应力公差基因和他们的适当等位基因的发现的几种技术的使用,改善的转基因的途径显著地在庄稼强调公差有一个极大地扩展的 germplasm 底和愿望的平行繁殖原则最后成功。 | Ray Bressan Hans Bohnert Jian-Kang Zhu | 2009 | Molecular Plant2009，2，1： | 12 |
| 6 | Sodium Stress in the Halophyte Thellungiella halophila and Transcriptional Changes in a thsos1-RNA Interference Line显示文摘The plasma membrane Na^+/H^+-antiporter salt overly sensitive1(SOS1)from the halophytic Arabidopsis-relative Thel-lungiella halophila(ThSOS1)shows conserved sequence and domain structure with the orthologous genes fromArabidopsis thaliana and other plants.When expression of ThSOS1 was reduced by RNA interference(RNAi),pronouncedcharacteristics of salt-sensitivity were observed.We were interested in monitoring altered transcriptional responsesbetween Thellungiella wild type and thsosl-4,a representative RNAi line with particular emphasis on root responses to saltstress at 350 mmol/L NaCl,a concentration that is only moderately stressful for mature wild type plants.Transcript profilingrevealed several functional categories of genes that were differently affected in wild-type and RNAi plants.Down-regulationof SOS1 resulted in different gene expression even in the absence of stress.The pattern of gene induction in the RNAi plantunder salt stress was similar to that of glycophytic Arabidopsis rather than that of wild type Thellungiella.The RNAi plantsfailed to down-regulate functions that are normally reduced in wild type Thellungiella upon stress and did not up-regulatefunctions that characterize the Thellungiella salt stress response.Metabolite changes observed in wild type Thellungiellaafter salt stress were less pronounced or absent in RNAi plants.Transcript and metabolite behavior suggested SOS1functions including but also extending its established function as a sodium transporter.The down-regulation of ThSOS1converted the halophyte Thellungiella into a salt-sensitive plant. | Dong-Ha Oh Qingqiu Gong Alex Ulanov Quan Zhang Youzhi Li Wenying Ma Dae-Jin Yun Ray A. Bressan Hans J. Bohnert | 2007 | Journal of Integrative Plant Biology2007，49，10： | 9 |
| 7 | HOS3, an ELO-Like Gene, Inhibits Effects of ABA and Implicates a S-1-P/Ceramide Control System for Abiotic Stress Responses in Arabidopsis thaliana显示文摘Arabidopsis thaliana 的 hyper-osmotically 敏感的异种,指明的 hos3-1 (渗透地应答的基因的高表示) ,基于它 RD29A 的超被识别: 在有 NaCl 和骆驼毛的织物的处理之上的 LUC 倡导者熔化植物。这些回答含有破坏基因作为 RD29A 压力应答的小径的一个直接或间接的否定管理者。由定序 T-DNA 边阶的 flanking 区域,破坏基因在地点 At4g36830,这被决定,作为与高相同编码通常认为的蛋白质到 CIG30 (ELO2/FEN1 ) 注解了。CIG30 在合成被含有很长锁住丰满的酸(VLCFA ) ,它是为 sphingolipids 和 ceramides 的必要先锋。改变了骆驼毛的织物超敏性特征的压力回答,包括减少的根生长抑制并且与骆驼毛的织物处理减少了萌芽并且从叶子减少了水损失,被突变而产生之遗传的 hos3-1 和 hos3-2 异种展出。hos3-2 异种部分在它的抄本丰富被压制并且作为一个后退的特点被继承。进一步,在 35SCaMV 倡导者的控制下面的 HOS3 ORF 象 RD29A 一样恢复了野类型的 NaCl 根和骆驼毛的织物根生长敏感: 在变异的植物的 LUC 光。我们也这里证明 HOS3 野类型的基因机能上地补充 elo2 和 elo3 酵母异种的敏感到 monensin。而且, hos3-1 和 hos3-2 等位基因分享了增加的敏感到除草剂 Metolachlor,它在 VLCFA 的合成禁止酰链延伸,并且 HOS3 机能上地补充了 elo2 和 elo3 并且恢复了 VLCFA 的层次。一起,这些数据证实 HOS3 禁止调停骆驼毛的织物的压力回答并且含有控制为不能生活的应力发信号和回答的几个方面指的 VLCFA 小径和产品。结果也在有气孔的行为的控制为 ceramide 的一个角色提供支持。 | Tanya M. Quist Irina Sokolchik Huazhong Shi Robert J. Joly Ray A. Bressan Albino Maggio Meena Narsimhan Xia Li | 2009 | Molecular Plant2009，2，1： | 7 |
| 8 | Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin,TGF-β1,IL-13 and oxidative stress显示文摘AIM To evaluate the therapeutic effects of bone marrowderived CD11b+CD14+ monocytes in a murine model of chronic liver damage. METHODS Chronic liver damage was induced in C57BL/6 mice by administration of carbon tetrachloride and ethanol for 6 mo. Bone marrow-derived monocytes isolated by immunomagnetic separation were used for therapy. The cell transplantation effects were evaluated by morphometry,biochemical assessment,immunohistochemistry and enzyme-linked immunosorbent assay. RESULTS CD11b+CD14+ monocyte therapy significantly reduced liver fibrosis and increased hepatic glutathione levels. Levels of pro-inflammatory cytokines,including tumor necrosis factor-α,interleukin(IL)-6 and IL-1β,in addition to pro-fibrotic factors,such as IL-13,transforming growth factor-β1 and tissue inhibitor of metalloproteinase-1 also decreased,while IL-10 and matrix metalloproteinase-9 increased in the monocytetreated group. CD11b+CD14+ monocyte transplantation caused significant changes in the hepatic expression of α-smooth muscle actin and osteopontin. CONCLUSION Monocyte therapy is capable of bringing about improvement of liver fibrosis by reducing oxidative stress and inflammation,as well as increasing antifibrogenic factors. | Veruska Cintia Alexandrino de Souza Thiago Almeida Pereira Valéria Wanderley Teixeira Helotonio Carvalho Maria Carolina Accioly Brelaz de Castro Carolline Guimaraes D’assuncao Andreia Ferreira de Barros Camila Lima Carvalho Virgínia Maria Barros de Lorena Vláudia Maria Assis Costa Alvaro Aguiar Coelho Teixeira Regina Celia Bressan Queiroz Figueiredo Sheilla Andrade de Oliveira | 2017 | World Journal of Gastroenterology2017，23，28： | 6 |
| 9 | Induced pluripotent stem cells throughout the animal kingdom:Availability and applications显示文摘Up until the mid 2000s, the capacity to generate every cell of an organism was exclusive to embryonic stem cells. In 2006, researchers Takahashi and Yamanaka developed an alternative method of generating embryonic-like stem cells from adult cells, which they coined induced pluripotent stem cells (iPSCs). Such iPSCs possess most of the advantages of embryonic stem cells without the ethical stigma associated with derivation of the latter. The possibility of generating “custom-made” pluripotent cells, ideal for patient-specific disease models, alongside their possible applications in regenerative medicine and reproduction, has drawn a lot of attention to the field with numbers of iPSC studies published growing exponentially. IPSCs have now been generated for a wide variety of species, including but not limited to, mouse, human, primate, wild felines, bovines, equines, birds and rodents, some of which still lack well-established embryonic stem cell lines. The paucity of robust characterization of some of these iPSC lines as well as the residual expression of transgenes involved in the reprogramming process still hampers the use of such cells in species preservation or medical research, underscoring the requirement for further investigations. Here, we provide an extensive overview of iPSC generated from a broad range of animal species including their potential applications and limitations. | Lais Vicari de Figueiredo Pessoa Fabiana Fernandes Bressan Kristine Karla Freude | 2019 | World Journal of Stem Cells2019，11，8： | 4 |
| 10 | The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response显示文摘 | Zhou J M Loh Y T Bressan R Y | 1995 | Cell1995，83，： | 2 |
| 11 | Localization of Banana bunchy top virus and cellular compartments in gut and salivary gland tissues of the aphid vector Pentalonia nigronervosa显示文摘香蕉成串的最高的病毒(BBTV )(Nanoviridae:Babuvirus ) 被类 Pentalonia 的蚜虫以一种循环性的方式播送。由到唾液的腺的从前面的 midgut 的 BBTV translocates,上皮的纸巾没被理解的细胞的机制。这里,我们使用了多重荧光灯在内脏和 Pentalonia nigronervosa 的主要的唾液的腺学习分发和早、迟了的内涵体, macropinosomes, lysosomes,微导管,肌动朊细丝,和类脂化合物木排子域的细胞的本地化的标记。我们使用了 colabeling 试金,到有这些细胞的分隔空间和结构的 colocalize BBTV 病毒的粒子。我们的结果建议包括调停 clathrin 、调停 caveolae 的 endocytosis 和类脂化合物椽子,多重潜在的细胞的过程不能涉及 BBTV 成为主观。 | Shizu Watanabe Dulal Borthakur Alberto Bressan | 2016 | Insect Science2016，23，4： | 2 |
| 12 | PLANT CELLULAR AND MOLECULAR RESPONSES TO HIGH SALINITY显示文摘 | Paul M. Hasegawa Ray A. Bressan Jian-Kang Zhu Hans J. Bohnert | 2000 | Annual Review of Plant Physiology and Plant Molecular Biology2000，，： | 2 |
| 13 | Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect?An in vivo quantitativeepidepride SPET study of amisulpride-treated patients显示文摘 | Bressan RA Erlandsson K Jones HM | 2003 | Am J Psychiatry2003，160，8： | 1 |
| 14 | Standardization and interlaborato- ry reproducibility assessment of pulsed-field gel electrophoresis-generated fingerprints ofAcinetobacter baumannii显示文摘 | Seifert H Dolzani L Bressan R | 2005 | J Clin Microbiol2005，43，： | 1 |
| 15 | Diurnal variation of radon and mixing heights along a coast: a case study 显示文摘 | Hsu S A Larson R E Bressan D J | 1980 | Journal of Geophysical Research1980，85，： | 1 |
| 16 | Psoriasis, lymphoma and etanercept : is there a correlation 显示文摘 | Miranda LQ Bressan AL Rehfeldt FV | 2012 | An Bras Dermatol2012，87，1： | 1 |
| 17 | Synthetic Natural Gas (SNG) from Petcoke : Model Development and Simulation 显示文摘 | Sudiro M ZaneUa C Bressan L | 2009 | Chemical Engineering Transactions2009，17，9： | 1 |
| 18 | Prolactinemia is uncoupled from central D 2 /D 3 dopamine receptor occupancy in amisulpride treated patients显示文摘 | Rodrigo A. Bressan Kjell Erlandsson Edgar P. Spencer Peter J. Ell Lyn S. Pilowsky | 2004 | Psychopharmacology2004，，3： | 1 |
| 19 | Loss of Halophytism by Interference with SOS1 Expression1[W][OA]显示文摘 | Oh Dong-Ha Leidi Eduardo Zhang Quan Hwang Sung-Min Li Youzhi Quintero Francisco J Jiang Xingyu D’Urzo Matilde Paino Lee Sang Yeol Zhao Yanxiu Bahk Jeong Dong Bressan Ray A Yun Dae-Jin Pardo José M Bohnert Hans J | 2009 | Plant Physiology2009，，1： | 1 |
| 20 | Ion homeostasis in NaCl stress environments显示文摘 | Niu X Bressan RA Hasegawa PM Pardo JM | 1995 | Plant Physiol1995，109，： | 1 |
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