|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | American Academy of Audiology Childhood Hearing Screening Guidelines显示文摘 | Bright K Eichwald J Loveland CO | 2011 | 2011，，： | 1 |
| 2 | Coassembly of flotillins induces formation of membrane microdomains,mem brane curvature, and vesicle budding显示文摘 | FRICK M BRIGHT N A RIENTO K | 2007 | Curr Biol2007，17，13： | 1 |
| 3 | Impact of glycosy-lation on the immunogenicity of a DNA-based influenza H5HA vaccine显示文摘 | Bright R A Ross T M Subbarao K | 2003 | Elsevier Sci2003，308，： | 1 |
| 4 | ABA, hydrogen peroxide and nitric oxide signaling in stomatal guard cells 显示文摘 | Desikan R Cheung M K Bright J | 2004 | J Exp Bot2004，55，395： | 1 |
| 5 | Protozoan size influences algal pigment degradation during grazing显示文摘 | Strom S L Morello T A Bright K J | 1998 | Mar Ecol Prog Ser1998，164，： | 1 |
| 6 | Exploring the Relationships Between Organizational Virtuousness and Performance 显示文摘 | Cameron K S Bright D Caza A | 2004 | A merican Behavioral Scientist2004，，06： | 1 |
| 7 | Protein kinase C delta (deitaPKC)-annexin V interaction: a required step in deltaPKC translocation and function 显示文摘 | Kheifets V Bright R Inagaki K | 2006 | Biol Chem2006，281，23： | 1 |
| 8 | Assessment of the Antiviral Properties of Zeolites Containing MetalIons显示文摘 | BRIGHT K R SICAIROS-RUELAS E E GUNDY Pa tricia M | 2009 | Food Environ Virol2009，，1： | 1 |
| 9 | VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human meligmant mesothelioma tumours显示文摘 | OHTA Y SHRIDHAR V BRIGHT R K | 1998 | Br J Cancer1998，81，1： | 1 |
| 10 | Protein ki-nase C delta (deltaPKC)-annexin V interaction:arequired step in deltaPKC translocation and function显示文摘 | Kheifets V Bright R Inagaki K | 2006 | J Biol Chem2006，281，23： | 1 |
| 11 | ABA, hydrogen peroxide and nitric oxide signaling in stomatal guard cells 显示文摘 | Desikan R Cheung M K Bright J | 2004 | J Exp Bot2004，395，： | 1 |
| 12 | New criteria for diagnosis of infective endoearditis: utilization of specific echocardiographic findings: Duke Endocarditis Service显示文摘 | DURACK D T LUKES A S BRIGHT D K | 1994 | Am J Med1994，96，： | 1 |
| 13 | VEGF and VEGF tape c play an important role in angiogenesis and lymphagiogenesis in human malignant mesotheliona turnours显示文摘 | Ohta Y Shridhar V Bright R K | 1999 | Br J Cancer1999，81，1： | 1 |
| 14 | Inter-strain differences in nitrogen use by the coccolithophore Emiliania huxleyi, and conse- quences for predation by a planktonic ciliate 显示文摘 | Storm S L Bright K J | 2009 | Harmful Algae2009，8，5： | 1 |
| 15 | Statins Enhance Formation of Phagocyte Extracellular Traps显示文摘 | Ohn A. Chow Maren von K?ckritz-Blickwede A. Taylor Bright Mary E. Hensler Annelies S. Zinkernagel Anna L. Cogen Richard L. Gallo Marc Monestier Yanming Wang Christopher K. Glass Victor Nizet | 2010 | Cell Host & Microbe2010，，5： | 1 |
| 16 | Dietary mixing in a generalist herbivore: tests of two hypotbeses显示文摘 | Bernays E A Bright K L Gonzalez N | 1994 | Ecolo gy1994，75，： | 1 |
| 17 | DNA cancer vaccination strategies target SV40 large tumour antigen in a murine experimental metastasis model显示文摘 | Watts A M Bright R K Kennedy R C | 2000 | Dev Biol (Basel)2000，104，： | 1 |
| 18 | Periodontal liga- ment-derived cells for periodontal regeneration in animal models: A systematic review 显示文摘 | Bright R Hynes K Gronthos S | 2015 | J Periodontal Res2015，50，2： | 1 |
| 19 | Serum outperforms plasma in small extracellular vesicle microRNA biomarker studies of adenocarcinoma of the esophagus显示文摘BACKGROUND Circulating microRNAs(miRNAs)are potential biomarkers for many diseases.However,they can originate from non-disease specific sources,such as blood cells,and compromise the investigations for miRNA biomarkers.While small extracellular vesicles(sEVs)have been suggested to provide a purer source of circulating miRNAs for biomarkers discovery,the most suitable blood sample for sEV miRNA biomarker studies has not been defined.AIM To compare the mi RNA profiles between matched serum and plasma s EV preparations to determine their suitability for biomarker studies.METHODS Matched serum and plasma samples were obtained from 10 healthy controls and10 patients with esophageal adenocarcinoma.s EV isolates were prepared from serum and plasma using Exo Quick TM and quantified using Nano Sight.RNA was extracted from s EV preparations with the mi RNeasy Serum/Plasma kit and profiled using the Taqman Openarray q PCR.The overall mi RNA content and theexpression of specific mi RNAs of reported vesicular and non-vesicular origins were compared between serum and plasma s EV preparations.The diagnostic performance of a previously identified multi-mi RNA biomarker panel for esophageal adenocarcinoma was also compared.RESULTS The overall mi RNA content was higher in plasma s EV preparations(480 mi RNAs)and contained 97.5%of the mi RNAs found in the serum s EV preparations(412 mi RNAs).The expression of commonly expressed mi RNAs was highly correlated(Spearman’s R=0.87,P<0.0001)between the plasma and serum s EV preparations,but was consistently higher in the plasma s EV preparations.Specific blood-cell mi RNAs(hsa-mi R-223-3 p,hsa-mi R-451 a,mi R-19 b-3 p,hsa-mi R-17-5 p,hsa-mi R-30 b-5 p,hsa-mi R-106 a-5 p,hsa-mi R-150-5 p and hsa-mi R-92 a-3 p)were expressed at 2.7 to 9.6 fold higher levels in the plasma s EV preparations compared to serum s EV preparations(P<0.05).In plasma s EV preparations,the percentage of protein-associated mi RNAs expressed at relatively higher levels(Ct 20-25)was greater than serum s EV preparations(50%vs 31%).While the percentage of vesicle-associated mi RNAs expressed at relatively higher levels was greater in the serum s EV preparations than plasma s EV preparations(70%vs 44%).A 5-mi RNA biomarker panel produced a higher cross validated accuracy for discriminating patients with esophageal adenocarcinoma from healthy controls using serum s EV preparations compared with plasma s EV preparations(AUROC 0.80 vs 0.54,P<0.05).CONCLUSION Although plasma s EV preparations contained more mi RNAs than serum s EV preparations,they also contained more mi RNAs from non-vesicle origins.Serum appears to be more suitable than plasma for s EV mi RNAs biomarkers studies. | Karen Chiam George C Mayne Tingting Wang David I Watson Tanya S Irvine Tim Bright Lorelle T Smith Imogen A Ball Joanne M Bowen Dorothy M Keefe Sarah K Thompson Damian J Hussey | 2020 | World Journal of Gastroenterology2020，26，20： | 1 |
| 20 | Stall precur-sor identification in high speed compressor stages using ehaotie time series analysis methods显示文摘 | Bright M M Qammar H K Weigl H J | | 0，，03： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员