|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 2 | Dualistic water cycle pattern and its evolution in Haihe River basin显示文摘The Haihe River basin is widely recognized as an area in China which is most severely affected by human activities.The water resources utilization and recycling in the basin is very complex, and the characteristic of the dualistic water cycle is becoming more and more prominent.The ever-growing demand of water for modern industry and domestic life nearly dries up all the natu-ral runoff.Meanwhile, industrial, agricultural and domestic wastewater discharges cause severe deterioration in water quality.Consequently, many of water courses are either dried out or being heavily polluted.Modern water resources management can no longer rely on the 'monitoring-rehabilitation' model which was originally developed based on the natural water cycle.This paper analyzes the critical characteristics, water balance, and evolution of water flux process based on the theory of dualistic water cycle.Referring to the water cycle in the Haihe River basin, a schematic diagram was drawn to describe the dualistic water cycle pattern.Ten different parameters affecting mainly the evolution of water flux in the 'dualistic water cycle' are closely examined using the newly-collected data.As a result, this paper proposes several water management and control strategies to achieve healthy wa-ter status for the Haihe River basin. | LIU JiaHong QIN DaYong WANG Hao WANG MingNa YANG ZhiYong | 2010 | Chinese Science Bulletin2010，55，16： | 18 |
| 3 | Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment显示文摘A couple with a proband child of GJB2(encoding the gap junction protein connexin 26)-associated hearing impairment and a previous pregnancy miscarriage sought for a reproductive solution to bear a healthy child. Our study aimed to develop a customized preconception-to-neonate care trajectory to fulfill this clinical demand by integrating preimplantation genetic diagnosis(PGD), noninvasive prenatal testing(NIPT), and noninvasive prenatal diagnosis(NIPD) into the strategy. Auditory and genetic diagnosis of the proband child was carried out to identify the disease causative mutations. The couple then received in-vitro-fertilization treatment, and eight embryos were obtained for day 5 biopsy. PGD was performed by short-tandem-repeat linkage analysis and Sanger sequencing of GJB2 gene. Transfer of a GJB2 c.235del C heterozygous embryo resulted in a singleton pregnancy. At the 13 th week of gestation, genomic DNA(g DNA) from the trio family and cell-free DNA(cf DNA) from maternal plasma were obtained for assessment of fetal chromosomal aneuploidy and GJB2 mutations. NIPT and NIPD showed the absence of chromosomal aneuploidy and GJB2-associated disease in the fetus, which was later confirmed by invasive procedures and postnatal genetic/auditory diagnosis. This strategy successfully prevented the transmission of hearing impairment in the newborn, thus providing a valuable experience in reproductive management of similar cases and potentially other monogenic disorders. | XIONG WenPing WANG DaYong GAO Yuan GAO Ya WANG HongYang GUAN Jing LAN Lan YAN JunHao ZONG Liang YUAN Yuan DONG Wei HUANG SeXin WU KeLiang WANG YaoShen WANG ZhiLi PENG HongMei LU YanPing XIE LinYi ZHAO Cui WANG Li ZHANG QiuJing GAO Yun LI Na YANG Ju YIN ZiFang HAN Bing WANG Wei CHEN Zi-Jiang WANG QiuJu | 2015 | Science China(Life Sciences)2015，58，9： | 12 |
| 4 | β-diversity Patterns of Plant Community in Fragmented Habitat in a Degenerated Meadow in Songnen Plain,China显示文摘A number of isolated islands of Leymus chinensis + herbosa community were investigated in fragmented habitat islands,by Braun-Blanquet field survey approach,in a degenerated meadow in the Songnen Plain,China in 2007.These islands were classified as large,medium,and small scales on the basis of the island area(100-1000m2,large island;50-100m2,middle island;10-50m2,small island).Each scale of the investigation involved eight islands.The responses of β-diversity patterns of plant taxon to the habitat fragmentation at local community and metacommunity levels were analyzed on different scales of 24 isolated islands.The results indicated that at the local community level,there were 57 species belonging to 20 families and 49 genera in large islands,49 species belonging to 16 families and 40 genera in middle islands,and 27 species belonging to eight families and 23 genera in small islands.β-diversity indexes for species,genus and family in large,middle,and small islands varied greatly,and the highest value of the indexes was not noted in the largest island.However,the average of the data obtained at the three scales showed that across large islands,Whittaker indexes were low and Bray-Curtis similarity indexes were high,while across small islands,Whittaker indexes were high and Bray-Curtis similarity indexes were low.At the metacommunity level,Whittaker indexes for species and genus showed a great significantly negative double logarithmic correlation(p<0.01) with the island area,whereas the Bray-Curtis indexes for species,genus and family showed a great significantly positive double logarithmic correlation(p<0.01) with the island area.At both local community and metacommunity levels,turnovers of species and genus could respond more sensitively to spatial changes of plant diversity patterns than that of family.Hence,the species and the genus could be used for the analysis of β-diversity patterns of plant community. | HAN Dayong LI Haiyan YANG Yunfei | 2009 | Chinese Geographical Science2009，19，4： | 11 |
| 5 | Super-resolution dipole orientation mapping via polarization demodulation显示文摘Fluorescence polarization microscopy(FPM)aims to detect the dipole orientation of fluorophores and to resolve structural information for labeled organelles via wide-field or confocal microscopy.Conventional FPM often suffers from the presence of a large number of molecules within the diffraction-limited volume,with averaged fluorescence polarization collected from a group of dipoles with different orientations.Here,we apply sparse deconvolution and least-squares estimation to fluorescence polarization modulation data and demonstrate a super-resolution dipole orientation mapping(SDOM)method that resolves the effective dipole orientation from a much smaller number of fluorescent molecules within a sub-diffraction focal area.We further apply this method to resolve structural details in both fixed and live cells.For the first time,we show that different borders of a dendritic spine neck exhibit a heterogeneous distribution of dipole orientation.Furthermore,we illustrate that the dipole is always perpendicular to the direction of actin filaments in mammalian kidney cells and radially distributed in the hourglass structure of the septin protein under specific labelling.The accuracy of the dipole orientation can be further mapped using the orientation uniform factor,which shows the superiority of SDOM compared with its wide-field counterpart as the number of molecules is decreased within the smaller focal area.Using the inherent feature of the orientation dipole,the SDOM technique,with its fast imaging speed(at sub-second scale),can be applied to a broad range of fluorescently labeled biological systems to simultaneously resolve the valuable dipole orientation information with super-resolution imaging. | Karl Zhanghao Long Chen Xu-San Yang Miao-Yan Wang Zhen-Li Jing Hong-Bin Han Michael Q Zhang Dayong Jin Jun-Tao Gao Peng Xi | 2016 | Light(Science & Applications)2016，5，1： | 11 |
| 6 | Using the nematode Caenorhabditis elegans as a model animal for assessing the toxicity induced by microcystin-LR显示文摘Among more than 75 variants of microcystin(MC),microcystin-LR(MC-LR) is one of the most common toxins.In this study,the feasibility of using Caenorhabditis elegans to evaluate MC-LR toxicity was studied.C.elegans was treated with MC-LR at different concentrations ranging from 0.1 to 80 μg/L.The results showed that MC-LR could reduce lifespan,delay development,lengthen generation time,decrease brood size,suppress locomotion behavior,and decreases hsp-16-2-gfp expression.The endpoints of generation time,brood size,and percentage of the population expressing hsp-16-2-gfp were very sensitive to 1.0 μg/L of MC-LR,and would be more useful for the evaluation of MC-LR toxicity.Furthermore,the tissue-specific hsp-16-2-gfp expressions were investigated in MC-LR-exposed animals,and the nervous system and intestine were primarily affected by MC-LR.Therefore,the generation time,brood size,and hsp-16-2-gfp expression in C.elegans can be explored to serve as valuable endpoints for evaluating the potential toxicity from MC-LR exposure. | LI Yunhui WANG Yang YIN Lihong PU Yuepu WANG Dayong | 2009 | Journal of Environmental Sciences2009，21，3： | 9 |
| 7 | Effect of corrosive media on galvanic corrosion of complicated tri-metallic couples of 2024 Al alloy/Q235 mild steel/304 stainless steel显示文摘Galvanic corrosion of tri-metallic couples is more complicated than that of bi-metallic couples. In this study, the effect of the pH of corrosive media on the galvanic corrosion of 2024 A1 alloy/Q235 mild steel/304 stainless steel tri-metallic couples was investigated using potentiodynamic polarization, scanning electron microscopy, scanning vibrating electrode technique and a multi-channel galvanic corrosion meter. The results show that 2024 always acts as the only anode in 3.5 wt% NaCl at pH 5.56,9.72 and 12.0, while both Q235 and 2024 act as anodes at pH 2.39 in the initial stage and then the role of Q235 changes at longer coupling time, which can be attributed to the effect of pH on the surface film of 2024. It is also found that the galvanic current density of a tri-metallic couple is the superposition of two bi-metallic couples when cathodic reactions are controlled by the diffusion of oxygen, otherwise it is smaller than that of the sum of two bi-metallic couples. The localized corrosion instead of uniform corrosion of anodic metal is accelerated by galvanic corrosion. | Linjun Shi Xiuying Yang Yingwei Song Dan Liua Kaihui Dong Dayong Shan En-Hou Han | 2019 | Journal of Materials Science & Technology2019，35，9： | 8 |
| 8 | Necessity and feasibility for an ET-based modern water resources management strategy: A case study of soil water resources in the Yellow River Basin显示文摘The necessity and feasibility of an ET-based modern water resources management was analyzed to improve assessment of critical water resources scarcity in the region/basin. This analysis was based on the whole water cycle process and its analysis object is evapotranspiration (ET), a main consumption component in the water resources dynamic transformation process. A case study was undertaken by selecting soil water resources in the Yellow River Basin and employing the WEP-L distributed hydrological model with physics mechanisms. This paper discusses the amount and consumption efficiency of soil-water resources according to completely simulated results of water cycle elements throughout the basin. Results indicate that it is important for the ET-based modern water resources management strategy to alleviate water resources scarcity because it may not only avoid unused water wasting but also improve water use efficiency. Therefore, an ET-based modern water resources management scheme is a good complement to the traditional water resources demand management system. | WANG Hao YANG GuiYu JIA YangWen QIN DaYong GAN Hong WANG JianHua HAN ChunMiao | 2009 | Science China(Technological Sciences)2009，52，10： | 6 |
| 9 | Confirmation of combinational effects of calcium with other metals in a paper recycling mill effluent on nematode lifespan with toxicity identification evaluation method显示文摘We used toxicity identification evaluation (TIE) method to confirm the combinational effects of identified toxic metals in a paper recycling mill effluent in inducing the decreased lifespan in nematode Caenorhabditis elegans.Exposure to Ca + Al caused more severely decreased lifespan than that exposed to Ca,or Al;and exposure to Ca + Fe induced more severely decreased lifespan than that exposed to Ca,or Fe.Exposure to Ca+Al+Fe caused more severely decreased lifespan than that exposed to Ca,or Ca+Fe.Moreover,the baseline toxicity on lifespan was doubled by doubling the concentration of combined metals (Ca+Al+Fe) in spiking test in original effluent (oe),and lifespan defects in oe+Ca+Al+Fe exposed nematodes were more severe than that in Ca+Al+Fe exposed nematode.Therefore,Ca+Al+Fe exposure may largely explain the formation of decreased lifespan induced by the examined industrial effluent.Furthermore,the observed reduction of lifespan induced by the combination of high level of Ca with other metals may be at least partially independent of the insulin-like pathway. | Dayong Wang,Yang Wang,Lulu Shen Key Laboratory of Developmental Genes and Human Disease in Ministry of Education,Department of Genetics and Developmental Biology,Southeast University Medical School,Nanjing 210009,China. | 2010 | Journal of Environmental Sciences2010，22，5： | 6 |
| 10 | A novel imidazoline derivative as corrosion inhibitor for P110 carbon steel in hydrochloric acid environment显示文摘novel imidazoline derivative,2-methyl-4-phenyl-1-tosyl-4,5-dihydro-1H-imidazole(IMI),was prepared and investigated as corrosion inhibitor for P110 carbon steel in 1.0 M HCl solution by weight loss measurements,potentiodynamic polarization and electrochemical impedance spectroscopy(EIS)tests.The inhibition efficiency increased with the rising concentration of IMI inhibitor.The test results and fitting data indicated that the IMI behaved as a mixed-type inhibitor and obeys the Langmuir adsorption isotherm.Scanning electron microscopy(SEM)was carried out to investigate the surface of carbon steel specimens,showing great protection from aggressive solution.Finally,inhibition mechanism of IMI on metal surface was further discussed. | Lei Zhang Yi He Yanqiu Zhou Ranran Yang Qiangbin Yang Dayong Qing Qianhe Niu | 2015 | Petroleum2015，1，3： | 5 |
| 11 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 12 | Cephalopods of the “Falang Formation” (Triassic) from Guanling and Zhenfeng Counties, Guizhou Province, China显示文摘The 'Falang Formation' of western Guizhou was previously called the 'Halobia Bed' and considered to beLadinian in age. It was subdivided upward into the Zhuganpo, Laishike and Longchang members based on ammonites andthe Trachyceras multitubertulatum Zone of the Longchang Member was put in the Lower Carnian. Here in the presentpaper, 4 genera and 9 species of ammonites and 1 nautiloid genus and species collected from the upper part of the 'FalangFormation' (i.e. the Wayao Formation used in this paper, equivalent to the Laishike Member from Guanling and Zhenfengcounties are described. The geological and geographical distribution of these cephalopods, as well as the co-existingconodonts, put the Wayao Formation to the late early Carnian. | HAO Weicheng, SUN Yuanlin, JIANG Dayong, YANG Shouren and WANG Xinping Geological Museum, Peking University, Beijing 100871 | 2003 | Acta Geologica Sinica(English Edition)2003，77，4： | 5 |
| 13 | Introduction of fluorin into PBO polymer chains:Toward higher thermal stability and lower dielectric constant显示文摘A series of novel fluorinated benzoxazole polymers (6FPBO's) with high thermal stability and low dielectric constant were synthesized by copolymerization of 1,3-diamino-4, 6-dihydroxybenzene dihy-drochloride (DAR), 1,4-benzenedicarboxylic acid (PTA) and various amount of 4'4- (hexafluoroisopro-pylidene) bis (benzoic acid) (BIS-B-AF) in the medium of polyphosphoric acid (PPA). 6FPBO fibers were then obtained via dry-jet wet-spinning technique and characterized by means of Fourier transform infrared (FTIR) spectra, thermogravimetric analysis (TGA), single fiber tensile testing machine and scanning electron microscopy (SEM). FTIR spectrum of 6FPBO fibers indicated that the fluorine groups had been incorporated into PBO molecular chains successfully. TGA curves revealed that 6FPBO fibers possessed high thermal stability just as pure PBO fibers. Moreover, dielectric constant spectrum of 6FPBO exhibited that the polymers had low dielectric constant, especially in the range of high- frequency. | ZHANG Tao HU DaYong JIN JunHong YANG ShengLin LI Guang JIANG JianMing | 2009 | Science China(Technological Sciences)2009，52，1： | 4 |
| 14 | Electric-field-controlled superconductor–ferromagnetic insulator transition显示文摘Superconductivity beyond electron-phonon mechanism is always twisted with magnetism. Based on a new field-effect transistor with solid ion conductor as the gate dielectric(SIC-FET), we successfully achieve an electric-field-controlled phase transition between superconductor and ferromagnetic insulator in(Li,Fe)OHFeSe. A dome-shaped superconducting phase with optimal T_c of 43K is continuously tuned into a ferromagnetic insulating phase, which exhibits an electric-field-controlled quantum critical behavior. The origin of the ferromagnetism is ascribed to the order of the interstitial Fe ions expelled from the(Li,Fe)OH layers by gating-controlled Li injection. These surprising findings offer a unique platform to study the relationship between superconductivity and ferromagnetism in Fe-based superconductors. This work also demonstrates the superior performance of the SIC-FET in regulating physical properties of layered unconventional superconductors. | Likuan Ma Bin Lei Naizhou Wang Kaishuai Yang Dayong Liu Fanbao Meng Chao Shang Zeliang Sun Jianhua Cui Changsheng Zhu Tao Wu Zhe Sun Liangjian Zou Xianhui Chen | 2019 | Science Bulletin2019，64，10： | 4 |
| 15 | Study on consumption efficiency of soil water resources in the Yellow River Basin based on regional ET structure显示文摘Based on the regional water resources character, the concept of soil water resources is first redefined, and then associated with their transfer relationship in the hydrological cycle, Evapotranspiration (ET)-based consumption structure and consumption efficiency of soil water resources are analyzed. According to ET 's function in productivity, the consumption efficiency of soil water resources is di- vided into three classes: high efficient consumption from vegetation transpiration, low efficient con- sumption from soil evaporation among plants with high vegetation coverage and inefficient consump- tion from soil evaporation among plants with low vegetation coverage and bare soil evaporation. The high efficient and low efficient consumption were further classified as productive consumption. The ineffi- cient consumption is considered non-productive consumption because it is significant in the whole hydrological cycle process. Finally, according to these categories, and employing a WEP-L dis- tributed hydrological model, this paper analyzes the consumption efficiency of soil water resources in the Yel- low River Basin. The results show that there are 2078.89×108 m3 soil water resources in the whole basin. From the viewpoint of consumption structure, the soil water resources are comprised of 381.89×108 m3 transpiration consumption from vegetation and 1697.09×108 m3 evaporation consumption from soil among plants and bare soil. From the viewpoint of consumption efficiency, soil water re- sources are composed of 920.11×108 m3 efficient consumption and 1158.86×108 m3 of inefficient con- sumption. High efficient consumption accounts for 41.5 percent of the total efficient consumption of the whole basin, low efficient for 58.5 percent. Furthermore, consumption efficiency varies by region. Compared with ET from different land use conditions, the whole basin appears to follow the trend of having the greatest proportion of consumption as inefficient consumption, followed by low efficient consumption, and then the least proportion as high efficient consumption. The amount of inefficient consumption in some regions with vegetation is less than in other regions without vegetation. The amount of inefficient consumption in grasslands is much greater than in forestlands. However, the proportion of low efficient consumption is the greatest in crop fields. The amount of high efficient con- sumption in grasslands and forelands is similar to the corresponding low efficient consumption. However, the low efficient consumption in grasslands is larger than in the forelands. Therefore, when adjusting the utilization efficiency of soil water resources, vegetation coverage and plant structure should be modulated in terms of the principle of decreasing inefficient consumption, improving low efficiency ET and increasing high efficiency ET according to area character. | WANG Hao YANG GuiYu JIA YangWen QIN DaYong | 2008 | Science China Earth Sciences2008，51，3： | 3 |
| 16 | Soil restoration research advances of artificial sand-binding vegetation ecosystem in the Tengger Desert, Northern China显示文摘Soil plays an important role in desert ecosystem, and is vital in constructing a steady desert ecosystem. The management and restoration of desertified land have been the focus of much discussion. The soil in Shapotou desert region has developed remarkably since artificial sand-binding vegetation established in 1946. The longer the period of dune stabilization, the greater the thickness of microbiotic crusts and subsoil. Meanwhile, proportion of silt and clay increased significantly, and soil bulk density declinced. The content of soil organic matter, N, P, and K similarly increased. Therefore, soil has developed from aeolian sand soil to Calcic-Orthic aridisols. This paper discusses the effects brought about by dust, microbiotic soil crust and soil microbes on soil-forming process. Then, we analyzed the relation between soil formation and sand-binding vegetation evolution, in order to provide a baseline for both research on desert ecosystem recovery and ecological environment governance in arid and semi-arid areas. | LiWen Yang LiChao Liu DaYong Wang YongQing Zhang | 2010 | Research in Cold and Arid Regions2010，2，4： | 3 |
| 17 | Screening of Transgenic Soybean Transformed by Means of Pollen-tube Using Kanamycin显示文摘Kanamycin was used to screen T0 seeds of the variety Dongnong 46 transformed by means of pollen-tube method. The results showed that 400 mg·L-1 kanamycin could inhibit growth of non-transgenic plants, and 2 positive plants were gotten combined with Gus dyeing and PCR detection. It is proved that this method is e-conomic and effective in preliminary screening the transgenic plants. | ZHANG Shuzhen XU Pengfei ZHANG Dayong LIN Shifeng LI Wenbin HAN Yingpeng YANG Chuanping | 2006 | Journal of Northeast Agricultural University(English Edition)2006，13，1： | 2 |
| 18 | Exploration and implementation of commonality valuation method in commercial aircraft family design显示文摘Commercial aircraft family design can reduce development costs, shorten development cycles, and expand the market coverage of aircraft. Commercial aircraft family development has become one of the most important features of modern aircraft design. This paper explores the effects of commonality on different aircraft models in a commercial aircraft family. The existing product commonality indexes are summarized and their limitations in the application to aircraft design are discussed. Then a new component commonality index is proposed based on the component decomposition structure. A model for calculating the aircraft program value is established,which considers development costs, manufacturing costs, sale price, operation costs and residual costs. The effects of aircraft commonality on time and economic costs of both development and manufacturing, and on sale price, are analyzed and quantified. The commonality evaluation strategy is obtained, which features comprehensive consideration of the aircraft program value and time costs. The break-even analysis of aircraft is proceeded on the basis of costs and price data. By using a real option method, the strategy considers the uncertainty of the aircraft program and the flexibility of the manufacturer. This strategy proves to be rational and applicable to aircraft design based on the calculation of three examples and the analysis of parameter sensitivity. | Yongjie ZHANG Zheng YANG Xianchao MA Wenjun DONG Dayong DONG Zhaoguang TAN Shuai ZHANG | 2019 | Chinese Journal of Aeronautics2019，32，8： | 2 |
| 19 | Effect of coagulation temperature on structures and properties of poly(p-phenylene benzobisoxazole) (DHPBO) fibers during dry-jet wet-spinning process显示文摘The effect of coagulation temperature on the morphology, microstructures and mechanical properties of dihydroxy poly(p-phenylene benzobisoxazole) (DHPBO) fibers was investigated during dry-jet wet- spinning process, in which the coagulation bath concentration and drawn ratio were kept as 10 wt% of PPA in water and 1.7, respectively. The structures and mechanical properties of the as-spun DHPBO fibers were characterized by FTIR, XRD, SEM, and single fiber tensile testing. The results indicated that in PPA/H2O coagulation system, when the coagulation temperature was 25℃, highly crystallized DHPBO as-spun fibers possessing fine crystallites, circular and smooth morphology, and excellent mechanical properties could be achieved. | Tao Zhang JunHong Jin DaYong Hu ShengLin Yang Guang Li JianMing Jiang | 2009 | Science China(Technological Sciences)2009，52，4： | 2 |
| 20 | Reaction dynamics in the combustion synthesis system of Al-CrO_3-Al_2O_3-NaF-N_2-O_2显示文摘A new material with heat-resistant and adiabatic characteristics and high strength was prepared using the combustion syn- thesis method by mixed powders of CrO3, Al, Al2O3, and NaF in atmospheric gas. The reaction dynamic process of the Al-CrO3-NaF-Al2O3-N2-O2 new material system by the combustion synthesis method was discussed based on the observation results by SEM, EDS, and XRD in combination with the combustion front quenching method (CFQM) and the relation curves between re- action free enthalpies and the corresponding temperatures. The combustion synthesis mechanism and the formation reasons of the phase in the combustion product were analyzed. | Dazheng Yang Yue Zhang Degang Li Dianwei Qi Wei Deng Dayong Xun | 2007 | Journal of University of Science and Technology Beijing2007，14，3： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员