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| 1 | Multiple-aged granitoids and related tungsten-tin mineralization in the Nanling Range, South China显示文摘The Nanling metallogenic belt in South China is characterized by well-developed tungsten-tin mineralization related to multiple-aged granitoids.This belt is one of the 5 key prospecting and exploration areas among the 19 important metallogenic targets in China.Important progress has been made in recent years in understanding the Nanling granitoids and associated mineralization,and this paper introduces the latest major findings as follows:(1)there exists a series of Caledonian,Indosinian,and Yanshanian W-Sn-bearing granites;(2)the Sn-bearing Yanshanian granites in the Nanling Range form an NE-SW trending aluminous A-type granite belt that stretches over 350 km.The granites typically belong to the magnetite series,and dioritic micro-granular enclaves with mingling features are very common;(3)the Early Yanshanian Sn-and W-bearing granites possess different petrological and geochemical features to each other:most Sn-bearing granites are metaluminous to weakly peraluminous biotite(hornblende)granites,with zircon Hf(t)values of ca.2 to 8,whereas most W-bearing granites are peraluminous two-mica granites or muscovite granites with Hf(t)values of ca.8 to 12;(4)based on the petrology and geochemistry of the W-Sn-bearing granites,mineralogical studies have shown that common minerals such as titanite,magnetite,and biotite may be used as indicators for discriminating the mineralizing potential of the Sn-bearing granites.Similarly,W-bearing minerals such as wolframite may indicate the mineralizing potential of the W-bearing granites.Future studies should be focused on examining the internal relationships between the multiple-aged granites in composite bodies,the metallogenic peculiarities of multiple-aged W-Sn-bearing granites,the links between melt evolution and highly evolved ore-bearing felsic dykes,and the connections between granite domes and mineralization. | CHEN Jun WANG RuCheng ZHU JinChu LU JianJun MA DongSheng | 2013 | Science China Earth Sciences2013，56，12： | 46 |
| 2 | In vitro derivation of functional insulin-producing cells from human embryonic stem cells显示文摘为人的胚胎的茎(ES ) 的自强和区别的能力细胞为对待类型 Idiabetes mellitus 为胰腺的贝它细胞的产生使他们成为潜在的来源。这里,我们报导一最新发展了并且有效方法,在aserum免费的系统执行了,区分进生产胰岛素的 cells.Activin A 的导致的人的 ES 房间它在起始的阶段被使用从人的 EScells 导致权威的内胚叶区别,是由权威的内胚叶标记 Sox17 和 Brachyury.Further 的表示检测了, all-trans retinoic 酸( RA )被用来支持胰腺的区别,由早胰腺的抄写因素 pdx1 和 hlxb9 的表示显示了。在成熟 inDMEM/F12 以后有 bFGF 和菸碱的没有浆液的媒介,区分的房间表示了小岛特定的标记象 C 肽,胰岛素,胰高血糖素和 glut2 那样。百分比 ofC-peptide-positive 房间超过了 15% 。由这些房间的胰岛素和 C 肽的分泌物在葡萄糖层次对应于变化。当移植了进肾的囊时, ofStreptozotocin (STZ ) 对待裸体老鼠,这些区分的人的 ES 房间熬过并且维持贝它房间标记基因的表示包括 C 肽, pdx1, glucokinase, nkx6.1, IAPP, pax6and Tcf1。百分之三十只移植裸体老鼠展出了 stableeuglycemia 的明显的恢复;并且改正的显型被支撑超过六个星期。我们的新方法为学习人的胰开发的机制提供一个有希望的试管内区别模特儿并且说明为类型 Idiabetes mellitus 的处理使用人的 ES 房间的潜力。 | Wei Jiang Yan Shi Dongxin Zhao Song Chen Jun Yong Jing Zhang Tingting Qing Xiaoning Sun Peng Zhang Mingxiao Ding Dongsheng Li Hongkui Deng | 2007 | Cell Research2007，17，4： | 38 |
| 3 | Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population:the China-PAR project显示文摘Evidence on the lifetime risk for atherosclerotic cardiovascular disease(ASCVD) is insufficient;yet,estimating an individual's lifetime risk allows for a comprehensive assessment of ASCVD burden.We developed and validated lifetime risk prediction equations for ASCVD using four large and ongoing prospective cohorts of Chinese,the China-PAR project(Prediction for ASCVD Risk in China).Sexspecific equations were developed using two cohorts(as the derivation cohort) of 21,320 participants.Two other independent cohorts with 14,123 and 70,838 participants were used for their external validation,respectively.We evaluated both calibration and discrimination measures for model performance.Furthermore,we estimated ASCVD-free years lost or excess absolute risk attributable to high 10-year risk(!10.0%) and/or high lifetime risk(!32.8%).After 12.3 years' follow-up of the derivation cohort,1048 ASCVD events and 1304 non-ASCVD deaths were identified.Our sex-specific equations had good internal validation,with discriminant C statistics of 0.776(95% confidence interval [CI]:0.757–0.794) and 0.801(95% CI:0.778–0.825),and calibration χ~2 of 9.2(P = 0.418) and 5.6(P = 0.777) for men and women,respectively.Good external validation was also demonstrated with predicted rates closely matched to the observed ones.Compared with men having both low 10-year and low lifetime risk,men would develop ASCVD 3.0,4.6 and 8.6 years earlier if they had high 10-year risk alone,high lifetime risk alone,or both high 10-year and high lifetime risk at the index age of 35 years,respectively.We developed wellperformed lifetime risk prediction equations that will help to identify those with the greatest potential to avert ASCVD burden after implementation of innovative clinical and public health interventions in China. | Fangchao Liu Jianxin Li Jichun Chen Dongsheng Hu Ying Li Jianfeng Huang Xiaoqing Liu Xueli Yang Jie Cao Chong Shen Ling Yu Zhendong Liu Xianping Wu Liancheng Zhao Xigui Wu Dongfeng Gu Xiangfeng Lu | 2018 | Science Bulletin2018，63，12： | 30 |
| 4 | Modeling net primary productivity of the terrestrial ecosystem in China from 1961 to 2005显示文摘网络主要生产率(NPP ) 是代表生态系统的结构和函数的最重要的索引。NPP 能被动态全球植被模型(DGVM ) 模仿,它被设计相对环境变化代表植被动力学。这研究在气候,土壤,和地形学上与数据基于 DGVM 综合生物圈模拟器(朱鹭) 模仿了瓷器生态系统的 NPP。在瓷器陆上的生态系统的 NPP 模拟的朱鹭的适用性首先被验证。有另外的相关研究的比较显示范围和模拟的吝啬的价值通常在观察的限制以内;全面模式和全部的年度 NPP 接近与另外的模型一起进行的模拟。模拟基于遥感离 NPP 评价也靠近。确认证明那朱鹭能在瓷器自然生态系统在 NPP 的大规模模拟被利用。我们然后从 1961 ~ 2005 与气候变化数据模仿了 NPP,当温暖是特别地惹人注目的时。下列是模拟的结果。(1 ) 全部的 NPP 在过去的 45 年里从 3.61 GtC/yr 变化了到 4.24 GtC/yr 并且展出了最小的重要线性增加或减少。(2 ) 在增加的地区性的差别或在 NPP 的减少大,但是展出了一个不足道的全面线性趋势。NPP 在大多数部分衰退了东方并且华中,特别在黄土高原。(3 ) 类似于年度 NPP 的变化法律,季节的 NPP 也显示了不足道的增加或减少;趋势线在一般水平以内。(4 ) 在季节的 NPP 变化的地区性的差别大。NPP 在黄土高原在春天,夏天,和秋天衰退了,但是在西藏的高原的大多数部分增加了。 | YUAN Quanzhi WU Shaohong ZHAO Dongsheng DAI Erfu CHEN Li ZHANG Lei | 2014 | Journal of Geographical Sciences2014，24，1： | 27 |
| 5 | Dek35 Encodes a PPR Protein that Affects cis-Splicing of Mitochondrial nad4 Intron 1 and Seed Development in Maize显示文摘 | Xinze Chen Fan Feng Weiwei Qi Liming xu Dongsheng Yao Qun Wang Rentao Song | 2017 | Molecular Plant2017，10，3： | 24 |
| 6 | The high-resolution climate recorded in the δ^(18)O of Porites lutea from the Nansha Islands of China显示文摘A Porites lutea core from Yongshu Reef of Nansha Islands covering 50 years growth history was ana-ly/ed for oxygen isotopic composition with monthly and seasonally resolution. The calibration of the δ18O with the instrumental temperature indicated that the coral δ18O is a good indicator for sea surface temperature (SST) and air temperature (t). It can be used to reconstruct the SST and air temperature of the Yongshu Reef sea area. In addition, the coral δ18O provides signatures for the intensity of the East Asia monsoon and it is a record for the activities of El Nino events. With the calibrated SST and air temperature formulas, the most recent fifty years SST and air temperature were reconstructed based on the coral δ18O, thus back up the understanding of the climate of Nansha Islands to 1950. far beyond the limit of the instrumental recording since September 1988. It was found that, in general, increasing 1℃ air temperature results in 0.24‰decrease in skeletal δ18O. | YU Kefu, CHEN Tegu, HUANG Dingcheng, ZHAO Huanting, ZHONG Jinliang & LIU Dongsheng (LIU Tungsheng)South China Sea Institute of Oceanoiogy, Chinese Academy of Sciences. Guangzhou 510301, China:Geology and Geophysics Institute. Chinese Academy of Sciences, Beijing 100029, China | 2001 | Chinese Science Bulletin2001，46，24： | 10 |
| 7 | Three-dimensional in situ stress determination by anelastic strain recovery and its application at the Wenchuan Earthquake Fault Scientific Drilling Hole-1(WFSD-1)显示文摘In situ stress state becomes more and more significant with in-depth research on geodynamics and energy development.However,there has not been an economic and effective method developed to determine deep three-dimensional in situ stress.The Anelastic Strain Recovery(ASR)method is a newly developed technique that can determine three-dimensional in situ stresses.After the 12 May 2008 Ms8.0 Wenchuan earthquake,the ASR method was used for the first time in China's Mainland to measure the in situ stresses in the WFSD scientific boreholes in Sichuan Province,China.In this paper,the basic procedure of the ASR method is introduced in detail and the compliances of ASR for boring cores are investigated.The results show that the maximum principal stress direction was NW64°at a measured depth(MD)of 1173 m(vertical depth 1151 m)in WFSD-1.The ratio of shear mode to the volume mode compliance of ASR was 2.9.And the three principal stresses at 1173 m MD in WFSD-1are 43,28 and 25 MPa.Combined with stress measurement results determined using other in situ measurement methods along the Longmenshan fault zone,the directions of the maximum horizontal principal stress changes from E-W to NEE-SWW to NWW-SEE when moving from NE to SW along the Longmenshan fault zone.This change is in agreement with the stress regime of the Longmenshan fault zone of the Wenchuan Earthquake,which supports a stress regime consisting predominantly of thrusts in the southwest and strike-slip in the northeast. | SUN DongSheng LIN WeiRen CUI JunWen WANG HongCai CHEN QunCe MA YinSheng WANG LianJie | 2014 | Science China Earth Sciences2014，57，6： | 10 |
| 8 | Advanced rechargeable lithium-ion batteries based on bendable ZnCo2O4-urchins-on-carbon-fibers electrodes显示文摘ZnCo2O4-urchins-on-carbon-fibers 矩阵的一个新奇的班被设计了,描绘,并且过去常制作高效的精力存储设备。我们获得了 1180 妈数慲畴敲 ?L 癯 ? ㈱? 的一个可逆的锂存储能力 ?? 牣慥楳杮倠 ? 挠湯整瑮 ?? 桳牯 ? 整浲 ??? 琠敨浲污琠敲瑡敭瑮 ? 瑡 ??? 鲖 ? 栀氠睯牥愠摮甠灰牥焠慵瑮汩獥映牯搠楡祬洠湩浩浵琠浥数爔?爔 吗?? | Bin Liu Xianfu Wang Boyang Liu Qiufan Wang Dongsheng Tan Weifeng Song Xiaojuan Hou Di Chen Guozhen Shen | 2013 | Nano Research2013，6，7： | 10 |
| 9 | Lentiviral-mediated gene transfer into human adipose-derived stem cells:role of NELL1 versus BMP2 in osteogenesis and adipogenesis in vitro显示文摘(NELL1 ) 象 NEL 一样分子 1 是与 craniosynostosis 联系的一个有势力 osteogenic 因素。侵入人体气管粘膜的病菌,大多数通常为基因治疗使用了病毒的向量,有可以限制成骨的几劣势。以前的研究证明了 lentiviruses 能为骨头新生为基因治疗用作理想的向量。在这研究,编码人的 NELL1 和骨头的二 lentiviral 向量(LvNELL1 和 LvBMP2 ) 分别地,形态基因的 protein-2 (BMP2 ) 被构造。在 vitro 的人的脂肪质导出干细胞(hADSCs ) 的增长,成骨,和 adipogenesis 上的 LvNELL1 感染的效果被估计并且与 LvBMP2 的相比。结果显示出感染 LvNELL1 的那 hADSCs 能高效地并且稳定地 overexpress 目标基因。3-(4,5-dimethylthiazol-2-yl )-2,5-diphenyltetrazolium 溴化物试金结果表明了那 LvBMP2,然而并非 LvNELL1,提高了 hADSCs 的增长。对碱的磷酸酶活动和细胞的矿化作用的评价显示 LvNELL1 感染支持了 hADSCs 的 osteogenic 区别,并且效果与 LvBMP2 的是可比较的。实时聚合酶链反应(PCR ) 在 hADSCs 揭示了那 LvNELL1 感染 upregulated OSX 表情然而并非 RUNX2 表示。另外,分析显示出的 adipogenic 标记(类脂化合物微滴, peroxisome 激活 proliferator 受体,和脂蛋白脂肪分解酵素) LvNELL1 能戏剧性地禁止 hADSCs,而是 LvBMP2 的 adipogenic 区别,这没有如此的效果。一起拿,这些调查结果建议在 hADSCs 的调停 lentiviral 的 NELL1 基因转移可以是一条新奇、有希望的途径完成有效、精确的骨头新生。 | Yajing Liu Caiyun Chen Huixia He Dongsheng Wang LingLing E Zhongyu Liu Hongchen Liu | 2012 | Acta Biochimica et Biophysica Sinica2012，44，10： | 10 |
| 10 | Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders显示文摘Human genetic adaptation to high altitudes(>2500 m)has been extensively studied over the last few years,but few functional adaptive genetic variants have been identified,largely owing to the lack of deep-genome sequencing data available to previous studies.Here,w e build a list of putative adaptive variants,including 63 missense,7 loss-of-function;1,298 evolutionarily conserved variants and 509 expression quantitative traits loci.Notably,the top signal of selection is located in TMEM 247,a transmembrane protein-coding gene.The Tibetan version of TMEM 247 harbors one high-frequency(76.3%)missense variant,rsl 16983452(c.248C>T;p.Ala83Val);with the T allele derived from archaic ancestry and carried by>94%of Tibetans but absent or in low frequencies(<3%)in non-Tibetan populations.The rsl 16983452-T is strongly and positively correlated with altitude and significantly associated with reduced hemoglobin concentration(p=5.78×10^-5),red blood cell count(p=5.72×10^-7)and hematocrit(p=2.57×10^-6).In particular,TMEM247-rs 116983452 shows greater effect size and better predicts the phenotypic outcome than any E P A S1 variants in association with adaptive traits in Tibetans.Modeling the interaction between TM£M247-rsl 16983452 and EPAS1 variants indicates weak but statistically significant epistatic effects.Our results support that multiple variants may jointly deliver the fitness of the Tibetans on the plateau,where a complex model is needed to elucidate the adaptive evolution mechanism. | Lian Deng Chao Zhang Kai Yuan Yang Gao Yuwen Pan Xueling Ge Yaoxi He Yuan Yuan Yan Lu Xiaoxi Zhang Hao Chen Haiyi Lou Xiaoji Wang Dongsheng Lu Jiaojiao Liu Lei Tian Qidi Feng Asifullah Khan Yajun Yang Zi-Bing Jin Jian Yang Fan Lu Jia Qu Longli Kang Bing Su Shuhua Xu | 2019 | National Science Review2019，6，6： | 9 |
| 11 | Fruit and vegetable consumption,cardiovascular disease,and all-cause mortality in China显示文摘Evidence about the response patterns of fruit and vegetable consumption with the risk of cardiovascular disease(CVD)and allcause mortality was inconsistent.These associations were examined using a large-scale,population-based Chinese cohort comprising 100,728 participants.A food-frequency questionnaire was used to assess fruit and vegetable consumption.Outcomes were ascertained by interviewing individuals or their proxies and checking hospital records or death certificates.Cox proportional hazards regression was used to calculate hazard ratios(HRs)with 95% confidence intervals(CIs).At the 736,668 person-years of follow-up,3,677 CVD cases and 5,466 deaths were identified.The multivariable-adjusted HRs for CVD across increasing quartiles of total fruit and vegetable consumption were 1(reference),0.94(95%CI=0.85-1.04),0.89(95%CI=0.80-0.98),and 0.85(95%CI=0.77-0.95).Moreover,participants in the highest quartile displayed a 13% lower risk of all-cause mortality(HR=0.87;95%CI=0.80-0.95).A nonlinear dose-response relation was found for CVD,without additional benefits beyond a consumption of600 g d-1,whereas the all-cause mortality risk decreased along with higher consumption,with a linear trend.These associations remained significant for fruit consumption but not for vegetable consumption.Our findings indicated that greater fruit and vegetable consumption was significantly associated with a lower risk of CVD and all-cause mortality.Increasing fruit and vegetable consumption,especially fruit,in the general population would prevent CVD and premature mortality. | Jun Wang Fangchao Liu Jianxin Li Keyong Huang Xueli Yang Jichun Chen Xiaoqing Liu Jie Cao Shufeng Chen Chong Shen Ling Yu Fanghong Lu Xianping Wu Liancheng Zhao Ying Li Dongsheng Hu Jianfeng Huang Dongfeng Gu Xiangfeng Lu | 2022 | Science China(Life Sciences)2022，65，1： | 8 |
| 12 | Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing显示文摘Pathogenic bacteria pose a devastating threat to public health.However,because of the growing bacterial antibiotic resistance,there is an urgent need to develop alternative antibacterial strategies to the established antibiotics.Herein,iron-doped carbon dots(Fe-CDs,~3 nm)nanozymes with excellent photothermal conversion and photoenhanced enzyme-like properties are developed through a facile one-pot pyrolysis approach for synergistic efficient antibacterial therapy and wound healing.In particular,Fe doping endows CDs with photoenhanced peroxidase(POD)-like activity,which lead to the generation of heat and reactive oxygen species(ROS)for Gram-positive and Gram-negative bacteria killing.This study demonstrates Fe-CDs have significant wound healing efficiency of Fe-CDs by preventing infection,promoting fibroblast proliferation,angiogenesis,and collagen deposition.Furthermore,the ultrasmall size of Fe-CDs possesses good biocompatibility favoring clinical translation.We believe that the nanozyme-mediated therapeutic platform presented here is expected to show promising applications in antibacterial. | Yunhang Liu Bolong Xu Mingzhu Lu Shanshan Li Juan Guo Fangzhou Chen Xiaolu Xiong Zhe Yin Huiyu Liu Dongsheng Zhou | 2022 | Bioactive Materials2022，7，6： | 7 |
| 13 | Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria显示文摘Infections caused by drug-resistant“superbugs”pose an urgent public health threat due to the lack of effective drugs;however, certain mammalian proteins with intrinsic antibacterial activity might be underappreciated. Here, we reveal an antibacterial property against Gram-negative bacteria for factors VII, IX and X, three proteins with well-established roles in initiation of the coagulation cascade. These factors exert antibacterial function via their light chains (LCs). Unlike many antibacterial agents that target cell metabolism or the cytoplasmic membrane, the LCs act by hydrolyzing the major components of bacterial outer membrane, lipopolysaccharides, which are crucial for the survival of Gram-negative bacteria. The LC of factor VII exhibits in vitro efficacy towards all Gram-negative bacteria tested, including extensively drug-resistant (XDR) pathogens, at nanomolar concentrations. It is also highly effective in combating XDR Pseudomonas aeruginosa and Acinetobacter baumannii infections in vivo. Through decoding a unique mechanism whereby factors VII, IX and X behave as antimicrobial proteins, this study advances our understanding of the coagulation system in host defense, and suggests that these factors may participate in the pathogenesis of coagulation disorder-related diseases such as sepsis via their dual functions in blood coagulation and resistance to infection. Furthermore, this study may offer new strategies for combating Gram-negative “superbugs”. | Jinwu Chen Xiaojie Li Ling Li Ting Zhang Qing Zhang Fangming Wu Diyue Wang Hongze Hu Changlin Tian Dongsheng Liao Liang Zhao Danxia Song Yongyun Zhao Chuanfang Wu Xu Song | 2019 | Cell Research2019，29，9： | 6 |
| 14 | Quantitative estimation of the shrub canopy LAI from atmosphere-corrected HJ-1 CCD data in Mu Us Sandland显示文摘The leaf area index(LAI) is an important ecological parameter that characterizes the interface between vegetation canopy and the atmosphere.In addition,it is used by most process-oriented ecosystem models.This paper investigates the potential of HJ-1 CCD data combined with linear spectral unmixing and an inverted geometric-optical model for the retrieval of the shrub LAI in Wushen Banner of Inner Mongolia in the Mu Us Sandland.MODTRAN(Moderate Resolution Atmospheric Radiance and Transmittance Model) was used for atmospheric correction.Shrubland was extracted using the threshold of the normalized difference vegetation index,with which water bodies and farmland were separated,in combination with a vegetation map of the People's Republic of China(1:1000000).Using the geometric-optical model,we derive the per-pixel reflectance as a simple linear combination of two components,namely sunlit background and other.The fraction of sunlit background is related to the shrub LAI.With the support of HJ-1 CCD data,we employ linear spectral unmixing to obtain the fraction of sunlit background in an atmospherically corrected HJ image.In addition,we use the measured shrub canopy structural parameters for shrub communities to invert the geometric-optical model and retrieve the pixel-based shrub LAI.In total,18 sample plots collected in Wushen Banner of Inner Mongolia are used for validation.The results of the shrub LAI show good agreement with R2 of 0.817 and a root-mean-squared error of 0.173. | CHEN Wei1,2,CAO ChunXiang1,HE QiSheng1,2,GUO HuaDong3,ZHANG Hao1,2,LI RenQiang4,ZHENG Sheng1,2,XU Min1,2,GAO MengXu1,2,ZHAO Jian1,2,LI Sha1,NI XiLiang1,2,JIA HuiCong1,JI Wei1,TIAN Rong1,2,LIU Cheng1,2,ZHAO YuXing5 & LI JingLu6 1 State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University,Beijing 100101,China 2 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 3 Center for Earth Observation and Digital Earth,Chinese Academy of Sciences,Beijing 100190,China 4 China Key Laboratory of Ecological Network Observation and Modeling,Institute of Geographical Sciences and Natural Resources Research,Chinese Academy of Sciences,Beijing 100101,China 5 Ordos Forestry Sand Control Science Institute,Dongsheng 017000,China 6 Inner Mongolia Biomass Thermoelectricity Limited Company,Wushen 017300,China | 2010 | Science China Earth Sciences2010，53，S1： | 6 |
| 15 | Nonlinear mixed-effects height to crown base and crown length dynamic models using the branch mortality technique for a Korean larch( Larix olgensis ) plantations in northeast China显示文摘Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China. | Weiwei Jia Dongsheng Chen | 2019 | Journal of Forestry Research2019，30，6： | 6 |
| 16 | Study of latch-up immunization in bulk CMOS integrated circuits exposed to transient ionizing radiation显示文摘This paper presents experimental results of transient gamma irradiation effects on two kinds of circuits.One is a two-stage circuit consisting of a bipolar power device L7805CV and a bulk complementary metal-oxide-semiconductor(CMOS) device IDT6116,the other is a two-stage circuit consisting of a bipolar power device L7805CV and the equivalent circuit of the parasitic P-N-P-N structure in bulk CMOS devices.The results show that the L7805CV's output interruption after transient irradiation can prevent latch-up from occurring on the second stage circuit.The demanded minimum interruption duration to avoid latch-up varies with dose rate,and this is confirmed by the experimental results. | LI RuiBin CHEN Wei LIN DongSheng YANG ShanChao BAI XiaoYan WANG GuiZhen LIU Yan QI Chao MA Qiang | 2012 | Science China(Technological Sciences)2012，55，11： | 5 |
| 17 | A high-sensitivity H2S gas sensor based on optimized ZnO-ZnS nano-heterojunction sensing material显示文摘This paper reports a high-performance H2S gas sensing material that is made of ZnO nanowires(NWs)modified by an optimal amount of ZnS to form nano-hete rojunctions.Compared with the intrinsic ZnONWs,the three differently modified nano-heterostructure material ZnO-ZnS-x(x=5,10,15)shows significant improvement in sensing performance to H2S at the working temperatures of 100-400℃,especially in the low temperature range(<300℃).The chemiresistive sensor with ZnO-ZnS-10 sensingmaterial exhibits the largest response signal to H2S among all the other ZnO-ZnS-x(x=5,10,15,20)sensors.Its response signal to 5 ppm H2S at 150℃is about 2.7 times to that of the ZnO-NWs sensor.Besides,the ZnO-ZnS-10 sensor also features satisfactory selectivity and repeatability at 150℃.With the technical advantage attributed to the reduction of the redesigned band gap at the interface between ZnO and ZnS,the ZnO-ZnS hete ro structure sensor rather than the traditional ZnO-NWs sensor can be used for high-sensitivity application at low working temperature. | Pei Ding Dongsheng Xu Nan Dong Ying Chen Pengcheng Xu Dan Zheng Xinxin Li | 2020 | Chinese Chemical Letters2020，31，8： | 5 |
| 18 | Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling显示文摘Numerous circular RNAs(circ RNAs) have been identified as vital regulators in various cancers. The newly reported circular RNA ubiquitin-associated protein 2(circ UBAP2) is a critical player in cell growth and metastasis in various types of cancers, although its role in colorectal cancer(CRC) has yet to be fully elucidated. We find that circ UBAP2 is upregulated in CRC tissues and cell lines to induce autophagy both in vitro and in vivo. The effects of circ UBAP2 on migration, invasion, and proliferation may be partially related to autophagy. Mechanistically, we uncover that circ UBAP2 can directly interact with mi R-582-5 p and subsequently act as a micro RNA sponge to regulate the expression of the mi R-582-5 p target gene forkhead box protein O1(FOXO1) and downstream signaling molecules, which collectively advance the progression and metastasis of CRC. These results suggest that circ UBAP2 acts as an oncogene via a novel circ UBAP2/mi R-582-5 p/FOXO1 axis, providing a potential biomarker and therapeutic target for CRC management. | Feifei Chen Lei Guo Jiehui Di Man Li Dong Dong Dongsheng Pei | 2021 | Journal of Genetics and Genomics2021，48，12： | 5 |
| 19 | Interface-induced formation of onion-like alloy nanocrystals by defects engineering显示文摘缺点的控制介绍的能力,在基于磅的 nanocrystals (NC ) 的特别地成双的缺点提供可能性调整基于磅的 nanocatalyst 的表演。然而,因为高内部的紧张,精力在孪生的结构存在,在基于磅的 NC 的缺点的制造是足够地挑战性的。这里,我们证明在 PtCu nanoparticles 上提供精确控制的一条低温度的导致接口的汇编途径集合在 hexadecylamine/water 接口,产出暴露的像洋葱的 PtCu NC 成双的缺点的高密度。而且,弯曲机制被建议阐明膨胀的成双的缺点和格子(收缩) 的外观基于错误改正了扫描传播电子显微镜学分析。这个工作打开新线路在 metalbased 合金 NC 设计缺点,启用在催化作用的更多的机会。 | Wei Jia Yuen Wu Yifeng Chen Dongsheng He Jinpeng Li Yu Wang Zhuo Wang Wei Zhu Chen Chen Qing Peng Dingsheng Wang Yadong Li | 2016 | Nano Research2016，9，2： | 5 |
| 20 | Relationship between chronic diarrhea with normal colonoscopy findings and terminal ileum lesions显示文摘 | LI Hongling WANG Changcheng LIU Shuqing XU Dongsheng ZHANG Ju CHEN hongmei | 2014 | Chinese Medical Journal2014，，16： | 4 |
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