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802篇 您的检索式:作者名="Fan Cai"
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1A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV) infected pneumonia(standard version)显示文摘In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;and then named '2019 novel coronavirus(2019-nCoV)' by the World Health Organization(WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development;we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control(including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.Ying-Hui Jin Lin Cai Zhen-Shun Cheng Hong Cheng Tong Deng Yi-Pin Fan Cheng Fang Di Huang Lu-Qi Huang Qiao Huang Yong Han Bo Hu Fen Hu Bing-Hui Li Yi-Rong Li Ke Liang Li-Kai Lin Li-Sha Luo Jing Ma Lin-Lu Ma Zhi-Yong Peng Yun-Bao Pan Zhen-Yu Pan Xue-Qun Ren Hui-Min Sun Ying Wang Yun-Yun Wang Hong Weng Chao-Jie Wei Dong-Fang Wu Jian Xia Yong Xiong Hai-Bo Xu Xiao-Mei Yao Yu-Feng Yuan Tai-Sheng Ye Xiao-Chun Zhang Ying-Wen Zhang Yin-Gao Zhang Hua-Min Zhang Yan Zhao Ming-Juan Zhao Hao Zi Xian-Tao Zeng Yong-Yan Wang Xing-Huan Wang 2020Military Medical Research2020,7,1:161
2Treatment of gastric varices by endoscopic sclerotherapy using butyl cyanoacrylate:10 years' experience of 635 cases显示文摘背景胃的静脉曲张( GV )为有有丁基 cyanoacrylate ( BC )的门 hypertension.Endoscopic 注射的病人是威胁生活的,为 GV 的治疗的支柱,被报导了为为它在病人的幸存上的 GV 和影响的涂去的功效仍然需要的 varices.but 放血的 hemostasis 有效我们总结了的 clarification.Here 我们 10 years'practice 到的经验从 Januar 为 GV patients.Methods 用 BCCHENG Liu-fang WANG Zhi-qiang LI Chang-zheng CAI Feng-chun HUANG Qi-yang LINGHU En-qiang LI Wen CHAI Guo-jun SUN Guo-hui MAO Yong-ping WANG Yan-mei LI Jing GAO Ping FAN Tie-yan 2007Chinese Medical Journal2007,,23:51
3Effects of nonalcoholic fatty liver disease on the development of metabolic disorders显示文摘Fan, JG Li, F Cai, XB Peng, YD Ao, QH Gao, Y 2007中国生物学文摘2007,21,11:51
4Clinicopathologic significance of HER-2/neu protein expression and gene amplification in gastric carcinoma显示文摘AIM:To study the HER-2/neu protein expression and gene amplification in gastric carcinoma and their relation.METHODS:One hundred and forty-five formalin-fixed and paraffin-embedded tumor tissue samples from Chinese gastric carcinoma patients were studied with immunohistochemistry(IHC)and fluorescence in situ hybridization(FISH)methods.Clinicopathologic data about all patients were collected.RESULTS:The levels of HER-2 3+,HER-2 2+and HER21+were measurable in 6.9%,8.3%and 17.2%of the samples,respectively.No HER-2 was stained in 67.6% of the samples.FISH showed that HER-2 gene was amplified in 18 samples,10 HER-2 3+samples,5 HER-2 2+samples,and 3 HER-2 1+samples with IHC staining.HER-2 status was not correlated with the sex and age of patients,and tumor size,location or differentiation,but with the depth of invasion,TNM stage,lymph node and distant metastasis as well as histopathological classification of gastric cancer(P<0.05).CONCLUSION:All samples with IHC as HER-2 expression should be analyzed with FISH.Detection of HER-2 gene amplification can assess the malignant biological behaviors and prognosis of gastric cancer.Shi-Yan Yan Ying Hu Jian-Gao Fan Guo-Quan Tao Yong-Ming Lu Xu Cai Bao-Hua Yu Yi-Qun Du 2011World Journal of Gastroenterology2011,17,11:34
5Research on preservation and enrichment mechanisms of organic matter in muddy sediment and mudstone显示文摘Using multidiscipline methodologies, the differences in preservation and enrichment mechanisms of organic matter (OM) in muddy sediment and mudstone are investigated. In clay fractions, concentra- tions of TOC and chloroform bitumen “A” are significantly higher than those in coarser fractions. This indicates that clay minerals (CM) play an important role in enriching OM. The content of chloroform bitumen “A” increases obviously in the clay fraction, which reveals that dissolvable OM is the main composition of coalesce with clay minerals. Furthermore, TG and DTA data show that OM enrichment mechanisms and preservation forms have multiplicity. Several exothermic peaks in the DTA curves demonstrate that muddy sediment and mudstone contain a number of bioclasts and amorphous OM besides dissolvable OM. Through analyzing with XRD and DTA after mudstone samples were pretreated, the conclusions can be arrived at. Firstly, CM interlayer space of XRD curves and exothermic peaks of DTA curves both change as temperature increases. Secondly, the changes of CM interlayer space and exothermic peaks are concordant and stable around 350℃. All these are the features that OM enters CM interlayers to form stable organo-clay complexes. Therefore, the combination format of OM with CM is not only surface adsorption, partial OM enters CM interlayers to form stable organo-clay complexes. Finally, through the research on OM preservation forms and enrichment mechanisms in muddy sedi- ment and mudstone, the hydrocarbon-generation processes and the global carbon cycle and budget can be explained.CAI JinGong BAO YuJin YANG ShouYe WANG XingXin FAN DaiDu XU JinLi WANG AiPing 2007Science China Earth Sciences2007,50,5:25
6Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes显示文摘在从经由单性生殖和男性单性生殖的老鼠的胚胎的干细胞(haESCs ) 启用了在修改基因的动物的哺乳动物的房间和代的基因屏蔽的 haploid 的推导的最近的成功。然而, haESCs 是否能从首领被导出,仍然保持未知。这里,我们从 Macaca fascicularis 猴子的单性生殖的胚囊报导 haESCs 的推导。这些房间,作为 PG-haESCs 称为,是 pluripotent 并且能在 vitro 或在 vivo 区分到三胚胎的细菌层的房间。有趣地,一根猴子 PG-haESC 线(MPH1 ) 的 haploidy 与另一个(MPH2 ) 的相比是更稳定的,作为没有排序的激活荧光的房间(FACS ) ,由 haploid 房间的存在出现超过 140 天 haploid 房间的丰富。重要地,转基因的猴子 PG-haESC 线能被 lentivirus- 和 piggyBac 产生调停 transposon 的基因转移。而且,基因屏蔽在猴子 PG-haESCs 是可行的。我们的结果证明 PG-haESCs 能从猴子被产生,提供为在首领的基因分析的一个理想的工具。Hui Yang Zhen Liu Yu Ma Cuiqing Zhong Qi Yin Chikai Zhou Linyu Shi Yijun Cai Hanzhi Zhao Hui Wang Fan Tang Yan Wang Chenchen Zhang Xin-yuan Liu Dongmei Lai Ying Jin Qiang Sun Jinsong Li 2013Cell Research2013,23,10:22
7Therapeutic effect of Zijin capsule in liver fibrosis in rats显示文摘TherapeuticefectofZijincapsuleinliverfibrosisinratsCAIDaYongZHAOGang,CHENJiaChun,YEGanMei,BINGFeiHongandFANBuWuSubjecth...CAI Da Yong, ZHAO Gang, CHEN Jia Chun, YE Gan Mei, BING Fei Hong and FAN Bu Wu 1998World Journal of Gastroenterology1998,4,3:20
8Soil erosion along a long slope in the gentle hilly areas of black soil region in Northeast China显示文摘沿着在在在东北中国的黑土壤区域的轻轻的多山的区域的一个长斜坡的土壤侵蚀变化的特征被讨论。一个简化斜坡模型基于片断被用来分析在 Heshan 农场与不同斜坡长度在 10 个地阴谋上在 2003 和 2004 之间观察的流量数据和土壤侵蚀数据, Heilongjiang 省。我们发现土壤侵蚀在沿着斜坡或者改变的黑土壤区域在长斜坡上评价并且创造集中的侵蚀和星期侵蚀的其他的地区。每个地区的准确地方为不同降雨条件是不同的。在有更少和温和降水的一年里,小河不能发生在顶以内 50 m 在有大、集中的降水的一年里,小河能被形成从斜坡的顶甚至在 15 m 开始。CUI Ming CAI Qiangguo ZHU Axing FAN Haoming 2007Journal of Geographical Sciences2007,17,3:18
9Association between Ambient Air Pollution and Hospital Emergency Admissions for Respiratory and Cardiovascular Diseases in Beijing: a Time Series Study显示文摘Objective To investigate the association between ambient air pollution and hospital emergency admissions in Beijing. Methods In this study, a semi-parametric generalized additive model(GAM) was used to evaluate the specific influences of air pollutants(PM10, SO2, and NO2) on hospital emergency admissions with different lag structures from 2009 to 2011, the sex and age specific influences of air pollution and the modifying effect of seasons on air pollution to analyze the possible interaction. Results It was found that a 10 μg/m3 increase in concentration of PM10 at lag 03 day, SO2 and NO2 at lag 0 day were associated with an increase of 0.88%, 0.76%, and 1.82% respectively in overall emergency admissions. A 10 μg/m3 increase in concentration of PM10, SO2 and NO2 at lag 5 day were associated with an increase of 1.39%, 1.56%, and 1.18% respectively in cardiovascular disease emergency admissions. For lag 02, a 10 μg/m3 increase in concentration of PM10, SO2 and NO2 were associated with 1.72%, 1.34%, and 2.57% increases respectively in respiratory disease emergency admissions. Conclusion This study further confirmed that short-term exposure to ambient air pollution was associated with increased risk of hospital emergency admissions in Beijing.ZHANG Ying WANG Shi Gong MA Yu Xia SHANG Ke Zheng CHENG Yi Fan LI Xu NING Gui Cai ZHAO Wen Jing LI Nai Rong 2015Biomedical and Environmental Sciences2015,28,5:18
10The prognostic and therapeutic implications of circulating tumor cell phenotype detection based on epithelial-mesenchymal transition markers in the first-line chemotherapy of HER2-negative metastatic breast cancer显示文摘Background:Epithelial-mesenchymal transition(EMT)is implicated in the metastatic process and presents a chal-lenge to epithelial cell adhesion molecule-based detection of circulating tumor cells(CTCs),which have been demon-strated to be a prognostic indicator in metastatic breast cancer.Although evidence has indicated that heterogeneity of CTCs based on EMT markers is associated with disease progression,no standard recommendations have been established for clinical practice.This study aimed to evaluate the prognostic significance of dynamic CTC detection based on EMT for metastatic breast cancer patients.Methods:We enrolled 108 human epidermal growth factor receptor 2-negative metastatic breast cancer patients from the prospective phase III CAMELLIA study and applied the CanPatrol CTC enrichment technique to identify CTC phenotypes(including epithelial CTCs,biphenotypic epithelial/mesenchymal CTCs,and mesenchymal CTCs)in peripheral blood samples.Receiver operating characteristic curve analyses of total CTC count and the proportion of mesenchymal CTCs for predicting the 1-year progression-free survival(PFS)rate were conducted to determine the optimal cut-off values,and Kaplan-Meier analysis and Cox proportional hazards regression analysis were performed to investigate the prognostic value of the cut-off values of both total CTC count and the proportion of mesenchymal CTCs in combination.Results:For predicting the 1-year PFS rate,the optimal cut-off value of total CTC count was 9.5(Area under the curve[AUC]=0.538,95%confidence interval[CI]=0.418-0.657),and that of the proportion of mesenchymal CTCs was 10.7%(AUC=0.581,95%CI=0.463-0.699).We used the two cut-off values in combination to forecast PFS in which the total CTC count was equaled to or exceeded 10/5 mL with the proportion of mesenchymal CTCs surpassed 10.7%.Patients who met the combined criteria had significantly shorter median PFS than did those who did not meet the criteria(6.2 vs.9.9 months,P=0.010).A nomogram was constructed based on the criteria and significant clinicopatho-logical characteristics with a C-index of 0.613(P=0.010).Conclusions: The criteria, which combine the total CTC count and the proportion of mesenchymal CTCs, may be used to monitor therapeutic resistance and predict prognosis in patients with metastatic breast cancer.Xiuwen Guan Fei Ma Chunxiao Li Shiyang Wu Shangying Hu Jiefen Huang Xiaoying Sun Jiayu Wang Yang Luo Ruigang Cai Ying Fan Qiao Li Shanshan Chen Pin Zhang Qing Li Binghe Xu 2019Cancer Communications2019,39,1:15
11Efficacy and Safety of Zhuanggu Joint Capsules in Combination with Celecoxib in Knee Osteoarthritis: A Multi-center, Randomized, Double-blind, Double-dummy, and Parallel Controlled Trial显示文摘Xian-Long Zhang Jing Yang Liu Yang Jian-Guo Liu Xin-Yu Cai Wei-Ming Fan Xue-Qing Yun Jin-Zhong Ma Xi-Sheng Weng 2016Chinese Medical Journal2016,,8:14
12Alcohol consumption and metabolic syndrome among Shanghai adults: A randomized multistage stratified cluster sampling investigation显示文摘AIM: To examine the relations of alcohol consumption to the prevalence of metabolic syndrome in Shanghai adults. METHODS: We performed a cross-sectional analysis of data from the randomized multistage stratified cluster sampling of Shanghai adults, who were evaluated for alcohol consumption and each component of metabolic syndrome, using the adapted U.S. National Cholesterol Education Program criteria. Current alcohol consumption was defined as more than once of alcohol drinking per month. RESULTS: The study population consisted of 3953 participants (1524 men) with a mean age of 54.3 ± 12.1 years. Among them, 448 subjects (11.3%) were current alcohol drinkers, including 405 males and 43 females. After adjustment for age and sex, the prevalence of current alcohol drinking and metabolic syndrome in the general population of Shanghai was 13.0% and 15.3%, respectively. Compared with nondrinkers, the prevalence of hypertriglyceridemia and hypertension was higher while the prevalence of abdominal obesity, low serum high-density-lipoprotein cholesterol (HDL-C) and diabetes mellitus was lower in subjects who consumed alcohol twice or more per month, with a trend toward reducing the prevalence of metabolic syndrome. Among the current alcohol drinkers, systolic blood pressure, HDL-C, fastingplasma glucose, and prevalence of hypertriglyceridemia tended to increase with increased alcohol consumption. However, low-density-lipoprotein cholesterol concentration, prevalence of abdominal obesity, low serum HDL-C and metabolic syndrome showed the tendency to decrease. Moreover, these statistically significant differences were independent of gender and age.CONCLUSION: Current alcohol consumption is associated with a lower prevalence of metabolic syndrome irrespe- ctive of alcohol intake (g/d), and has a favorable influence on HDL-C, waist circumference, and possible diabetes mellitus. However, alcohol intake increases the likelihood of hypertension, hypertriglyceridemia and hyperglycemia. The clinical significance of these findings needs further investigation.Jian-Gao Fan Xiao-Bu Cai Lui Li Xing-Jian Li Fei Dai Jun Zhu 2008World Journal of Gastroenterology2008,14,15:13
13Roasting Properties of Pellets With Iron Concentrate of Complex Mineral Composition显示文摘Investigation was conducted on roasting properties of pellets with an iron concentrate of complex mineral composition.The results indicated that the pellets of complex mineral composition concentrate required higher preheating temperature and longer preheating time than that of single magnetite concentrate.Therefore,it is difficult for preheated pellets to withstand the mechanical collision in the roasting process in rotary kiln.It was found that after the iron concentrate being subjected to high pressure roll grinding,the specific surface area reached 2029.1 cm2/g.Consequently,the preheating and roasting temperature of pellets were decreased by 70 and 50 ℃ and preheating and roasting time were decreased by 2 and 4 min,respectively.Meanwhile,the compression strength of preheated and roasted pellets were increased by 200 N for a pellet and 220 N for a pellet,respectively.The mechanism lied in that the increase of specific surface area activated thermal reaction and promoted formation of inter-grain bridge.FAN Jian-jun QIU Guan-zhou JIANG Tao GUO Yu-feng CAI Mei-xia 2011Journal of Iron and Steel Research(International)2011,18,7:12
14Petrogenesis and tectonic implications of Late-Triassic high εNd(t)-εHf(t) granites in the Ailaoshan tectonic zone(SW China)显示文摘High εNd(t)-εHf(t) granites are robust evidence for crustal growth. In this paper we report results of petrologic, geochronological and geochemical investigations on the Huashiban granites from the Ailaoshan tectonic zone in western Yunnan(SW China). Zircon grains separated from the two samples(10HH-119 A and 10HH-120A) yield the weighted mean 206Pb/238 U ages of 229.9 ± 2.0 Ma and 229.3 ± 2.3 Ma, respectively, interpreted as the crystallization ages of the granites. Based on our results, in combination with the existing U-Pb geochronological data for the Ailaoshan metamorphic rocks, we propose that the Ailaoshan Group might be a rock complex composed of the Mesoproterozoic, Neoproterozoic, Hercynian, Indosinian and Himalayan components, rather than a part of the crystalline basement of the Yangtze block. The zircon grains show highly depleted Lu-Hf isotope compositions, with positive εHf(t) values ranging from 8.4 to 13.1. The Huashiban granites have high SiO2(72.66 wt%–73.70 wt%), low Mg#(0.28–0.34) with A/CNK=1.01–1.05, and can be classified as peralumious high-K calc-alkaline I-type granites. A synthesis of these data indicates that the Ailaoshan tectonic zone had evolved into a post-collisional setting by the Late-Triassic(229 Ma). Genesis of the Huashiban high εNd(t)-εHf(t) granites involved into two processes:(1) underplating of the sub-arc mantle into the lower crust, and(2) remelting of the juvenile crustal materials in response to the upwelling of the asthenospheric mantle in the post-collisional setting.LIU HuiChuan WANG YueJun FAN WeiMing ZI JianWei CAI YongFeng YANG GuangLin 2014Science China Earth Sciences2014,57,9:12
15Neuroprotective effects of Ginkgo biloba extract and GinkgoUde B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model显示文摘Xiaohan Yang Tiezheng Zheng Hao Hong Nan Cai Xiaofeng Zhou Changkai Sun Liying Wu Shuhong Liu Yongqi Zhao Lingling Zhu Ming Fan Xuezhong Zhou Fengxie Jin 2018Frontiers of Medicine2018,12,3:12
16Mechanism of aqueous fructus aurantii immaturus extracts in neuroplexus of cathartic colons显示文摘AIM: To examine the effect of aqueous fructus aurantii immaturus(FAI) extracts on the intestinal plexus of cathartic colons.METHODS: Cathartic colons were induced in rats with dahuang,a laxative used in traditional Chinese medicine. Once the model was established(after approximately 12 wk),rats were administered mosapride(1.54 mg/kg) or various doses of aqueous FAI extracts(1-4 g/kg) for 14 d. Transit function was assessed using an ink propulsion test. Rats were then sacrificed,and the ultramicrostructure of colonic tissue was examined using transmission electron microscopy. The expression of the 5-hydroxytryptamine receptor 4(5-HTR4) and neurofilament-H was assessed in colon tissues using real-time PCR,Western blot,and immunohistochemistry.RESULTS: Mosapride and high dose(4 g/kg) of aqueous FAI extracts significantly improved the bowel movement in cathartic colons compared to untreated model colons as measured by the intestinal transit rate(70.06 ± 7.25 and 72.02 ± 8.74,respectively,vs 64.12 ± 5.19; P < 0.05 for both). Compared to controls,the ultramicrostructure of cathartic colons showed signsof neural degeneration. Treatment with mosapride and aqueous FAI extracts resulted in recovery of ultrastructural pathology. Treatment with mosapride alone upregulated the gene and protein expression of 5-HTR4 compared to untreated controls(P < 0.05 for both). Treatment with aqueous FAI extracts(≥ 2 g/kg) increased 5-HTR4 m RNA levels(P < 0.05),but no change in protein level was observed by Western blot or immunohistochemistry. The m RNA and protein levels of neurofilament-H were significantly increased with mosapride and ≥ 2 g/kg aqueous FAI extracts compared to controls(P < 0.05 for all).CONCLUSION: Aqueous FAI extracts and mosapride strengthen bowel movement in cathartic colons via increasing the expression of 5-HTR4 and neurofilament-H.Shi-Yi Wang Yan-Ping Liu Yi-Hong Fan Lu Zhang Li-Jun Cai Bin Lv 2015World Journal of Gastroenterology2015,21,31:11
17Prevalence of cardiovascular disease in subjects hospitalized due to chronic obstructive pulmonary disease in Beijing from 2000 to 2010显示文摘ObjectivesTo 在为长期的妨碍的肺的疾病( COPD )就医的题目调查心血管的疾病( CVD )的全面流行,并且在10年的 period.MethodsMedical 上与 COPD 在病人探索主要 CVD 复杂并发症和趋势的流行在 PLA 医院将军,的记录北京联合医学院医院,并且到 2010/03/03 的从 2000/01/01 的北京医院回顾地被考察。有 COPD 的 4960 个病人的一个总数在学习被考察(3570 男性,意味着年龄, 72.2 ±10.5 年;1390 女性,意味着年龄, 72.0 ±10.4 年) 在 COPD 病人的 CVD 的 .ResultsThe 流行是 51.7% 。三很流行的 CVD 是 ischemic 心疾病(28.9%) ,心失败(19.6%) ,和心律不齐(12.6%) 。在 10 年的学习时期期间,在 COPD 病人的各种各样的 CVD 的流行与增加年龄显示出一个渐渐的增加趋势。由于 ischemic 心疾病有更高的病态(P <0.01 ) 在男 COPD 病人比在女对应物。然而,心失败(P <0.01 ) 并且高血压(P <0.01 ) 比在女 COPD 病人不太经常发生在男 COPD 病人。而且, ischemic 心疾病的流行逐年减少了。除了心失败,在 COPD 病人的 CVD 复杂并发症的各种各样的类型趋于发生在更年轻的题目。在女人的 CVD 的所有主要类型的流行趋于在就医的病人由 CVD 的 year.ConclusionsThe 流行增加年因为在北京的 COPD 高。年龄,性别和 CVD 趋势,以及生活方式变化,当预防和控制策略被提出时,应该被考虑。Hua Cui Dong-Mei Miao Zhi-Min Wei Jian-Fang Cai Yi Li Ai-Min Liu Fan Li 2012Journal of Geriatric Cardiology2012,9,1:11
18Long-term outcomes of gemcitabine and cisplatin in patients with recurrent or metastatic esophageal squamous cell carcinoma: a phase Ⅱ trial显示文摘背景食道的癌症是研究表明了的癌症相关的死亡 worldwide.Prior 的第六个很普通的原因在有 cisplatin.Therefore 的联合的 gemcitabine 的潜在的 synergistic antitumor 活动,我们为在2003年10月和2006年10月之间的食道的 cancer.Methods 学习了如此的联合的功效和 tolerability ,有食管的变形或周期性的先进有鳞的房间癌的 38 个病人是 enrolled.The 治疗的中部的数字每 patiHUANG Jing FAN Qing-xia CHEN Li LIU Ai-na CAI Rui-gang HAO Xue-zhi WANG Jin-wan SUN Yan 2011Chinese Medical Journal2011,,23:11
19Outline of Uranium Resources Characteristics and Metallogenetic Regularity in China显示文摘Uranium,as one of twenty-six kinds of important minerals in China,is strategic resource and energy mineral,which has been thoroughly investigated in the project of National Potential Evaluation of Uranium Resource.During the implementation of this project,the authors summarized the metallogenic regularity of uranium resource in China systematically,through the researches of geological characteristics of uranium resource,uranium deposits type(genetic and prediction type),temporal and spatial distribution,and metallogenic series.Based on the investigation of present situation and progress in uranium exploration,this paper proposes the uranium deposits in China should be divided into 4 classes,9 types,21 subtypes in genetic,and 50 types in prediction;suggests to divide China into 29 uranium metallogenic belts and 20 uranium prospective area,and constructs 20uranium-polymetallic metallogenic series,through summarizing temporal and spatial distribution characteristics and metallogenic regularity of uranium deposits in China.The above research is beneficial to the comprehensive understanding of regional uranium metallogenic regularity,and will direct the uranium exploration in the future.CAI Yuqi ZHANG Jindai LI Ziying GUO Qingyin SONG Jiye FAN Honghai LIU Wusheng QI Fucheng ZHANG Minglin 2015Acta Geologica Sinica(English Edition)2015,89,3:11
20Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China:focus on the safety显示文摘Background:World Health Organization recommends countries introducing new drug and short treatment regimen for drug resistant tuberculosis(DR-TB)should develop and implement a system for active pharmacovigilance that allows for detection,reporting and management of adverse events.The aim of the study is to evaluate the frequency and severity of adverse events(AEs)of bedaquiline-containing regimen in a cohort of Chinese patients with multidrug-resistant(MDR)/extensively drug-resistant(XDR)-TB based on active drug safety monitoring(aDSM)system of New Drug Introduction and Protection Program(NDIP).Jing-Tao Gao Juan Du Gui-Hui Wu Yi Pei Meng-Qiu Gao Leonardo Martinez Lin Fan Wei Chen Li Xie Yu Chen Hua Wang Long Jin Guo-Bao Li Pei-Lan Zong Yu Xiong Qian-Hong Wu Ming-Wu Li Xiao-Feng Yan Yan-Fang Miao Qing-Shan Cai Xin-Jie Li Da-Peng Bai Shu-Jun Geng Guo-Li Yang Pei-JunTang Yi Zeng Xiao-Hong Chen Tong-Xia Li Cui Cai Yun Zhou Ma Zhuo Jian-Yun Wang Wen-Long Guan Lin Xu Ji-Chan Shi Wei Shu Li-Li Cheng FeiTeng Yu-Jia Ning Shi-Heng Xie Yu-Xian Sun Li-Jie Zhang Yu-Hong Liu 2021Infectious Diseases of Poverty2021,10,2:11
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