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| 1 | COVID-19 Outbreak Caused by Contaminated Packaging of Imported Cold-Chain Products—Liaoning Province,China,July 2020显示文摘Summary What is known about this topic?Few major outbreaks of coronavirus disease 2019(COVID-19)have occurred in China after major nonpharmaceutical interventions and vaccines have been deployed and implemented.However,sporadic outbreaks that had high possibility to be linked to cold chain products were reported in several cities of China..What is added by this report?In July 2020,a COVID-19 outbreak occurred in Dalian,China.The investigations of this outbreak strongly suggested that the infection source was from COVID-19 virus-contaminated packaging of frozen seafood during inbound unloading personnel contact.What are the implications for public health practice?Virus contaminated paper surfaces could maintain infectivity for at least 17–24 days at-25℃.Exposure to COVID-19 virus-contaminated surfaces is a potential route for introducing the virus to a susceptible population.Countries with no domestic transmission of COVID-19 should consider introducing prevention strategies for both inbound travellers and imported goods.Several measures to prevent the introduction of the virus via cold-chain goods can be implemented. | Huilai Ma1 Jianqun Zhang Ji Wang Ying Qin Cao Chen Yang Song Liang Wang Jun Meng Lingling Mao Fengqin Li Ning Li Jian Cai Yong Zhang Dayan Wang Yunting Xia Hong Wang Shaofeng Jiang Xiang Zhao Peihua Niu Wenjie Tan Tao Ma Yecheng Yao Naiying Mao Zhen Zhu Tianjiao Ji Qian Yang Baoying Huang Li Zhao Jianxing Yu Li Bai Shuangli Zhu Dongyan Wang Yan Zhang Yingwei Sun Mingchun Luan Yanhai Wang Haibo Sun Shihong Yang Zhijian Bo Xiang Ren Zhongjie Li George Fu Gao Wei Yao Wenqing Yao Zijian Feng Wenbo Xu | 2021 | China CDC weekly2021，3，21： | 16 |
| 2 | Neuroprotective effects of Ginkgo biloba extract and GinkgoUde B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model显示文摘 | Xiaohan Yang Tiezheng Zheng Hao Hong Nan Cai Xiaofeng Zhou Changkai Sun Liying Wu Shuhong Liu Yongqi Zhao Lingling Zhu Ming Fan Xuezhong Zhou Fengxie Jin | 2018 | Frontiers of Medicine2018，12，3： | 12 |
| 3 | Glycine attenuates myocardial ischemia-reperfusion injury by inhibiting myocardial apoptosis in rats显示文摘Glycine is a well-documented cytoprotective agent.However,whether it has a protective effect against myocar-dial ischemia-reperfusion injury in vivo is still unknown.By using an open-chest anesthetized rat model,we found that glycine reduced the infarct size by 21% in ischemia-reperfusion injury rats compared with that in the vehicle-treated MI/R rats.The left ventricular ejection fraction and fractional shortening were increased by 19.11% and 30.98%,respectively,in glycine-treated rats.The plasma creatine kinase levels in ischemia-reperfusion injury rats decreased following glycine treatment.Importantly,administration of glycine significantly inhibited apoptosis in post-ischemia-reperfusion myocardium,which was accompanied by suppression of phosphorylated p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase,as well as the Fas ligand.These results suggest that gly-cine attenuates myocardial ischemia-reperfusion injury in vivo by inhibiting cardiomyocytes apoptosis. | Xiaozheng Zhong Xiaoyu Li Lingling Qiana Yiming Xu Yan Lu Jing Zhang Nan Li Xudong Zhu Jingjing Ben Qing Yang Qi Chen | 2012 | The Journal of Biomedical Research2012，26，5： | 10 |
| 4 | WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation显示文摘The hypobaric hypoxic environment in highaltitude areas often aggravates the severity of inflammation and induces brain injury as a consequence. However, the critical genes regulating this process remain largely unknown. The phosphatase wild-type p53-induced phosphatase 1(WIP1) plays important roles in various physiological and pathological processes, including the regulation of inflammation in normoxia, but its functions in hypoxic inflammation-induced brain injury remain unclear.Here, we established a mouse model of this type of injury and found that WIP1 deficiency augmented the release of inflammatory cytokines in the peripheral circulation and brain tissue, increased the numbers of activated microglia/macrophages in the brain, aggravated cerebral histological lesions, and exacerbated the impairment of motor and cognitive abilities. Collectively, these results provide the first in vivo evidence that WIP1 is a critical neuroprotector against hypoxic inflammation-induced brain injury. | Dahu Li Lijun Zhang Xin Huang Lili Liu Yunling He Lun Xu Yiyao Zhang Tong Zhao Liying Wu Yongqi Zhao Kuiwu Wu Yan Wu Ming Fan Lingling Zhu | 2017 | Neuroscience Bulletin2017，33，3： | 9 |
| 5 | Interaction of sleep quality and sleep duration on glycemic control in patients with type 2 diabetes mellitus显示文摘 | Tang Yunzhao Meng lingling Li Daiqing Yang Min Zhu Yanjuan Li Chenguang Jiang Zhenhuan Yu Ping Li Zhu Song Hongna Ni Changlin | 2014 | Chinese Medical Journal2014，，20： | 9 |
| 6 | Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19显示文摘The coronavirus disease 2019(COVID-19)caused by SARS-CoV-2 was identified in December 2019.The symptoms include fever,cough,dyspnea,early symptom of sputum,and acute respiratory distress syndrome(ARDS).Mesenchymal stem cell(MSC)therapy is the immediate treatment used for patients with severe cases of COVID-19.Herein,we describe two confirmed cases of COVID-19 in Wuhan to explore the role of MSC in the treatment of COVID-19.MSC transplantation increases the immune indicators(including CD4 and lymphocytes)and decreases the inflammation indicators(interleukin-6 and C-reactive protein).High-flow nasal cannula can be used as an initial support strategy for patients with ARDS.With MSC transplantation,the fracrion of inspired O2(Fi02)of the two patients gradually decreased while the oxygen saturation(Sa02)and partial pressure of oxygen(P02)improved.Additionally,the patients9 chest computed tomography showed that bilateral lung exudate lesions were adsorbed after MSC infusion.Results indicated that MSC transplantation provides clinical data on the treatment of COVID-19 and may serve as an alternative method for treating COVID-19,particularly in patients with ARDS. | Lingling Tang Yingan Jiang Mengfei Zhu Lijun Chen Xiaoyang Zhou Chenliang Zhou Peng Ye Xiaobei Chen Baohong Wang Zhenyu Xu Qiang Zhang Xiaowei Xu Hainv Gao Xiaojun Wu Dong Li Wanli Jiang Jingjing Qu Charlie Xiang Lanjuan Li | 2020 | Frontiers of Medicine2020，14，5： | 8 |
| 7 | Mechanism of acupuncture regulating visceral sensation and mobility显示文摘Chinese ancient medical scientists have long focused on the internal and external contacts between acupoints on the surface of the body and the viscera.The Miraculous Pivot(it is one of the earliest medical classics in China)stated,“Twelve regular channels belong to the zang-fu organs internally,and connect to the extremities and joints externally.”Traditional Chinese medicine considers acupoints as defined areas where the Qi of viscera and meridians are transfused.These include the reaction points of visceral diseases on the body surface as well as the acupuncture trigger points that promote the flow of Qi and blood,and regulate visceral function.Chinese ancient medical scientists classified the specificity of the main acupoints in the body based on the meridian doctrine,which has been instructing clinical application for about 2000 years.Laws on the domino effect of acupoints have mainly focused on conclusions to clinical experiences.Indications of some acupoints exceed the practical paradigm since the excessive extension occurred during theory derivation.The current research direction on acupuncture focuses on three aspects:the effectiveness of acupuncture and moxibustion;the relevances and associations between meridians and viscera;and the physical and chemical properties and relevant physical basis of acupoints.The relevance between meridians and viscera is the central theory in the meridian doctrine,and acupoints are regarded as an important link in the relationship between meridians and viscera.Specific relationships between acupoints and target organs exist.Stimulating different acupoints on the body surface can help deal with different diseases,especially visceral diseases.In addition,acupoints have a dual function of reflecting and treating visceral diseases.There is no systemic research available on acupoint specificity,despite current knowledge and clinical experiences,which results in a weak foundation for acupuncture theory.This study focuses on the relevance and associations between meridians and viscera.A summary of the mechanisms of acupuncture regulating visceral sensation and mobility and the specific relationships between acupoints and their target organs are presented in this review. | Peijing Rong Bing Zhu Yuqing Li Xinyan Gao Hui Ben Yanhua Li Liang Li Wei He Rupeng Liu Lingling Yu | 2011 | Frontiers of Medicine2011，5，2： | 8 |
| 8 | Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells显示文摘有各种各样的长度的 telomeres 的返老还童在导致的 pluripotent 干细胞(iPSCs ) 被发现了。telomere 长度规定的机制在 iPSCs 的正式就职和增长期间留下逃犯。我们证明 telomere 动力学在 reprogramming 和经过期间在鼠标 iPSCs 是可变的,并且建议这些差别多半源于多重潜在的因素,包括包括外长的 reprogramming 因素的表示的 telomerase 机械, telomerase 独立的机制和同种细胞的影响。用一个基因模型 telomerase 缺乏(为 iPSCs 的推导和段落的 Terc −/− 和 Terc +/−) 房间,我们发现 telomerase 在 iPSCs 的 reprogramming 和自强起一个关键作用。进一步,当由再结合的延伸和维护的其他的小径也被要求时, telomeres 的 telomerase 维护为真 pluripotency 的正式就职是必要的,然而并非足够。一起, telomere 生物学的几个方面可以在 iPSCs 说明可变 telomere 动力学。尤其是,采用在 iPSC reprogramming 期间维持 telomeres 的机制很类似于胚胎的干细胞的那些。这些调查结果可以也联系到这些机制能为在由体的房间的原子 reprogramming 以后的 telomere 异质负责的克隆的地原子转移。 | Fang Wang Yu Yin Xiaoying Ye Kai Liu Haiying Zhu Lingling Wang Maria Chiourea Maja Okuka Guangzhen Ji Jiameng Dan Bingfeng Zuo Minshu Li Qian Zhang Na Liu Lingyi Chen Xinghua Pan Sarantis Gagos David L Keefe Lin Liu | 2012 | Cell Research2012，22，4： | 7 |
| 9 | Recombinant adenovirus-p53(Gendicine) sensitizes a pancreatic carcinoma cell line to radiation显示文摘Objective:In this study,we examine the effects of recombinant adenovirus-p53(rAd-p53)on the pancreatic carcinoma cell line SW1990.Specifically,we determine if expression of rAd-p53 sensitizes these cells to radiation.Methods:Following transfection of SW1990 cells with rAd-p53,we measured expression of P53,P21 and Bax by immunocytochemistry.Both transfected and control cell lines were irradiated with a range of doses,and the survival fractions(SF)were calculated.Dose survival curves were constructed and modeled for comparison.Results:Transfection of SW1990 cells with rAd-p53 resulted in increased expression of P53,P21 and Bax in a time-dependent manner.At 96 h after transfection,89.92%of cells expressed P53,56.8%expressed P21,and 76.50%expressed Bax.The SF following radiation was lower in the rAd-p53 transfected cells compared to the control cells,suggesting that rAd-p53 sensitizes SW1990 cells to radiation(D0for the experimental and control groups was 2.199 and 2.462,respectively).Conclusions:Use of the adenoviral vector is an effective means of transfecting SW1990 cells with wild-type P53,and this sensitizes the cell line to irradiation.This work suggests that combining rAd-p53with radiation therapy in pancreatic cancer may be therapeutically beneficial. | Jinluan Li Jianji Pan Xianggao Zhu Ying Su Lingling Bao Sufang Qiu Changyan Zou Yong Cai Junxin Wu Ivan W.K.Tham | 2013 | Chinese Journal of Cancer Research2013，25，6： | 6 |
| 10 | Large-eddy simulation of the generation and propagation of internal solitary waves显示文摘A modified large-eddy simulation model,the dynamic coherent eddy model(DCEM)is employed to simulate the generation and propagation of internal solitary waves(ISWs)of both depression and elevation type,with wave amplitudes ranging from small,medium to large scales.The simulation results agree well with the existing experimental data.The generation process of ISWs is successfully captured by the DCEM method.Shear instabilities and diapycnal mixing in the initial wave generation phase are observed.The dissipation rate is not equal at different locations of an ISW.ISW-induced velocity field is analyzed in the present study.The structure of the bottom boundary layer(BBL)of internal wave packets is found to be different from that of a single ISW.A reverse boundary jet instead of a separation bubble exists behind the leading internal wave while separation bubbles appear in other parts of the wave-induced velocity field.The boundary jet flow resulting from the adverse pressure gradients has distinctive dynamics compared with free shear jets. | ZHU Hai WANG LingLing TANG HongWu | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，6： | 6 |
| 11 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 12 | Spatial-temporal Evolution Characteristics and Decoupling Analysis of Influencing Factors of China’s Aviation Carbon Emissions显示文摘The aviation industry has become one of the top ten greenhouse gas emission industries in the world. China’s aviation carbon emissions continue to increase, but the analysis of its influencing factors at the provincial level is still incomplete. This paper firstly uses Stochastic Impacts by Regression on Population, Affluence and Technology model(STIRPAT) model to analyze the time series evolution of China’s aviation carbon emissions from 2000 to 2019. Secondly, it uses the Logarithmic Mean Divisia Index(LDMI) model to analyze the influencing characteristics and degree of four factors on China’s aviation carbon emissions, which are air transportation revenue, aviation route structure, air transportation intensity and aviation energy intensity. Thirdly, it determines the various factors’ influencing direction and evolution trend of 31 provinces’ aviation carbon emissions in China(not including Hong Kong, Macao, Taiwan of China due to incomplete data). Finally, it derives the decoupling effort model and analyzes the decoupling relationship and decoupling effort degree between air carbon emissions and air transportation revenue in different provinces. The study found that from 2000 to2019, China’s total aviation carbon emissions continued to grow, while the growth rate of aviation carbon emissions showed a fluctuating downward trend. Air transportation revenue and aviation route structure promote the growth of total aviation carbon emissions, and air transportation intensity and aviation energy intensity have a restraining effect on the growth of total aviation carbon emissions. The scope of negative driving effect of air transportation revenue and air transportation intensity on total aviation carbon emissions in various provinces has increased. While the scope of positive driving influence of aviation route structure on total aviation carbon emissions of various provinces has increased, aviation energy intensity mainly has negative driving influence on total aviation carbon emissions of each province. Overall, the emission reduction trend in the areas to the west and north of the Qinling-Huaihe River Line is obvious. The decoupling mode between air carbon emissions and air transportation revenue in 31 provinces is mainly expansion negative decoupling.The air transportation intensity effect shows strong decoupling efforts in most provinces, the decoupling effort of aviation route structure effect and aviation energy intensity effect is not prominent. | HAN Ruiling LI Lingling ZHANG Xiaoyan LU Zi ZHU Shaohua | 2022 | Chinese Geographical Science2022，32，2： | 5 |
| 13 | A D-optimal Multi-position Calibration Method for Dynamically Tuned Gyroscopes显示文摘This paper presents a novel experimental design to greatly improve the calibration accuracy of the acceleration-insensitive bias and the acceleration-sensitive bias of the dynamically tuned gyroscopes(DTGs).In order to reduce experimental cost,the D-optimal criteria with constraints are constructed.The turntable positions and the number of test points are chosen to build D-optimal experimental designs.The D-optimal experimental designs are tested by multi-position calibration experiment for tactical-grade DTGs.Test results show that,with the same cost,the fit uncertainty is reduced by about 50% by using the D-optimal 8-position experimental procedure,compared to using a defacto standard experimental procedure in ANSI/IEEE Std 813-1988.Furthermore,the new experimental procedure almost achieves optimal accuracy with only 12-position which is half the cost of the widely adopted 24-position experimental procedure for achieving optimal accuracy. | FU Li ZHU Yongquan WANG Lingling WANG Xinling | 2011 | Chinese Journal of Aeronautics2011，24，2： | 5 |
| 14 | Progress in the development of techniques based on light scattering for single nanoparticle detection显示文摘Nanoparticles have recently attracted extensive attention in view of their great potential in biomedicine and bioanalytical ap- plications. Single particle detection via light scattering offers a simple and efficient approach for the size, size distribution, and concentration analysis of nanoparticles. In particular, intrinsic heterogeneity or rare events masked by ensemble averaging can be revealed. However, the sixth power dependence of Rayleigh scattering on particle size makes it very challenging to detect individual nanoparticles of small sizes. This article is intended to provide an overview of recent progress in the development of techniques based on light scattering for the detection of single nanoparticles. | ZHU ShaoBin, WANG Shuo, YANG LingLing, HUANG TianXun & YAN XiaoMei Department of Chemical Biology, College of Chemistry and Chemical Engineering Key Laboratory for Chemical Biology of Fujian Province Key Laboratory of Analytical Science, Xiamen University, Xiamen 361005, China | 2011 | Science China Chemistry2011，54，8： | 5 |
| 15 | Antimicrobial effect of sodium houttuyfonate on Staphylococcus epidermidis and Candida albicans biofilms显示文摘OBJECTIVE: To study antimicrobial effect of Sodium houttuyfonate(SH) on Staphylococcus epidermidis(SE) and Candida albicans(CA). METHODS: The prepared strain broths(OD600 =0.05) containing SE and CA were firstly used to test the minimal inhibitory concentrations(MICs) of SH, azithromycin(AZM) and fluconazole(FLU) by micro-dilution method. Then the biofilms of SE and CA were matured in 96-well plates, and co-cultured with SH, AZM and FLU for 1, 2 and 3 days to assess the antibiofilm efficacies of the agents with different concentrations by crystal violet staining method. At last, the treated biofilms of SE and CA by 2× MIC agents were observed by scanning electronic microscope. RESULTS: The MICs of SE and CA were 256 and 1024 μg/mL, respectively. After the 1st, 2nd and 3rd day of medications, the suppressions of biofilm were about 60%(P<0.01), 76%(P=0.000) and 75%(P=0.000) by 2×MIC SH, the suppressions of biofilm were about 90%(P=0.000), 88%(P=0.000) and 90%(P=0.000) by 2×MIC SH, which could be testified by scanning electron microscope results. However, the inhibitions of biofilm attachment had no significant difference for SE by SH and azithromycin and CA by SH and fluconazole. CONCLUSION: SH had widely anti-pathogenic effect on pathogenic biofilm formation of either bacteria or fungus, had more influence on enclosed cells of SE and CA than the traditional antibiotics, revealing its target might be the extracellular polymeric substances, and was more active to inhibit the growth of CA than SE. | Jing Shao Huijuan Cheng Daqiang Wu Changzhong Wang Lingling Zhu Zhenxin Sun Qiangjun Duan Weifeng Huang Jinliang Huang | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 4 |
| 16 | Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia显示文摘Background and purpose The inflammatory response mediated by microglia/macrophages is closely related to cerebral ischaemia/reperfusion injury.Wild-type p53-induced protein phosphatase 1(Wip1),a serine/threonine phosphatase,is expressed in various tissues.A growing number of reports have suggested that Wip1 is a negative regulator of inflammation in peripheral tissue;however,its role in the central nervous system(CNS)remains unclear.This study aimed to clarify whether Wip1 can inhibit CNS inflammation by regulating microglia/macrophage functions after ischaemic injury.Methods A model of middle cerebral artery occlusion and reperfusion was established in mice.CNS inflammation was simulated by lipopolysaccharide treatment of primary microglia.Laser speckle imaging was used to monitor regional cerebral blood flow.Behavioural outcomes were assessed with a TreadScan gait analysis system.TTC staining was used to evaluate the infarct volume,and western blotting and immunofluorescence staining were applied to detect the phenotypical transformation of microglia.ELISA was performed to detect the levels of inflammatory factors.Results Wip1 expression was increased after ischaemia/reperfusion.Wip1-knockout(KO)mice displayed more severe brain injury than wild-type mice,as indicated by aggravated motor dysfunction,greater brain infarct volumes and higher expression of inflammatory cytokines(interleukin-6 and tumour necrosis factor alpha)in the brain.We also found that Wip1 depletion increased microglial/macrophage activation in both in vitro and in vivo models,which all showed activation of microglia/macrophages.Lentivirus-Ppm1d reversed the injury induced by Wip1-KO.Conclusions Our results suggest that Wip1 may inhibit neuroinflammation by inhibiting microglial/macrophage activation after brain ischaemia/reperfusion injury. | Feng Yan Xiang Cheng Ming Zhao Shenghui Gong Ying Han Liping Ding Di Wu Yumin Luo Wei Zuo Lingling Zhu Ming Fan Xunming Ji | 2021 | Stroke & Vascular Neurology2021，6，3： | 4 |
| 17 | Electroluminescence efficiency in bilayer organic light-emitting devices with LiF/Al cathode显示文摘An analytical model to calculate electroluminescence (EL) efficiency of bilayer organic light-emitting devices, considering the influence of introducing LiF insulating buffer layer at metal/organic interface on the barrier height for electron injection, was presented. The relations of EL efficiency versus the applied voltage and injection barrier or internal interfacial barrier or the thickness of organic layer were discussed. The results indicate that: (1) when δ e/δ h < 2, metal/organic (M/O) interface is ohmic contact; when δ e/δ h > 2, M/O becomes contact limited; and when δ e/δ h = 2 (Φ h ~ 0.2 eV, Φ e ~ 0.3 eV), there is a transition from ohmic contact to contact limited; (2) η EL decreases with the increase of δ′e / δ′h; however, when δ′e / δ′h > 2.5 (H ′h~ 0.2 eV, H ′e~ 0.4 eV), the changes of η EL are very small, which shows that η EL is dominated by the carrier’s injection; (3) when increasing Lh/L, η R has a descending trend at low voltage and a rising one at higher voltage. For a given Lh/L, η EL first increases and then decreases with the increasing applied voltage, and as Lh/L further increases, the variation tendency of η EL is more obvious. These conclusions are in agreement with the reported theoretic and experimental results. | LI HongJian ZHU RuHui YAN LingLing ZHANG HaiYan | 2007 | Science China(Physics,Mechanics & Astronomy)2007，50，1： | 4 |
| 18 | Photodegradation of benzene by TiO_2 nanoparticles prepared by flame CVD process显示文摘Photodegradation of benzene at ppb levels by mixed-phase TiO 2 nanoparticles, synthesized by the oxidation of TiCl 4 in propane/air turbulent flame chemical vapor deposition (CVD) process, is investigated experimentally by using a tubular photoreactor with thin TiO 2 films coated on the reactor wall by sedimentation. Effects of inlet benzene concentration from 10 to 300 g/m 3 , rutile mass fraction from about 20 to 50% and photoluminescence (PL) intensity of TiO 2 nanoparticles on degradation degree are examined under the conditions of 70% relative humidity, 38 g/cm 2 catalyst loading, 24 mW/cm 2 UV irradiation of 254 nm and 5.7 s residence time in the reactor. Based on experimental results, separation of photo-induced electron (e- ) and hole (h + ) pairs by rutile phase is discussed as photo-induced electron (e- ) in anatase phase will migrate to rutile surface due to that the potential of conductive band of rutile is lower than that of anatase, leading to more holes ready on anatase surface for oxidation reactions. | Hongyong Xie Luping Zhu Lingling Wang Shengwen Chen Dandan Yang Lijun Yang Guilan Gao Hao Yuan | 2011 | Particuology2011，9，1： | 3 |
| 19 | Voltage-dependent anion channel involved in the α-synuclein-induced dopaminergic neuron toxicity in rats显示文摘包含神经蛋白质 -synuclein 的包括身体(-syn) 在几 neurodegenerative 疾病被观察,包括 Parkinson 的疾病(PD ) 。而且,在老鼠大脑的 -syn 的在表示上部分由在 substantia nigra (SN ) 触发 dopaminergic 神经原的退化模仿 neuropathological 和 PD 的行为的特征。Mitochondrial 机能障碍对 PD 致病也中央,并且 -syn 在线粒体被发现。然而, -syn-induced neurotoxicity 的精确机制留下逃犯。检验 -syn-induced neurodegeneration 的潜在的机制,我们在用 recombinant 的老鼠的 SN 的过去表示的 -syn 联系 adeno 的病毒的向量(rAAV-syn ) 。把结果标记的 Immunohistochemical 和 immunogold 显示 -syn 在向量注射以后在 SN 和 striatum 是成功地过去表示的。酷氨酸的数字 hydroxylase 积极(dopaminergic ) 神经原显著地在当时,与 rAAV-syn 注射的老鼠被减少与控制老鼠相比。与控制老鼠相比, -syn-conjugated 金牌粒子的密度在轴突是更大的,细胞质,原子核,并且尤其是另外在在 rAAV-syn-injected 老鼠的 SN 神经原的线粒体。另外,有 rAAV-syn 的 SN 神经原 transfected 与不连续的外部膜和内部像液泡的结构展出了肿的线粒体,强烈建议 -syn-induced mitochondrial 机能障碍。在 rAAV-syn-injected 老鼠的线粒体也在 autophagosomes 被观察。有电压依赖者阴离子隧道 1 的 -Syn co-immunoprecipitated (VDAC1 ) ,导致 mitochondrial 解开的 mitochondrial 渗透转变毛孔(mPTP ) 的一个部件和 apoptosis。-syn 的在表示上可以通过和 mitochondrial VDAC1 的一个相互作用引起 dopaminergic 神经原的退化,它导致 mPTP 激活,解开的 mitochondrial,和房间死亡。 | Lingling Lu Chunyan Zhang Qing Cai Qiang Lu Chunli Duan Yuangang Zhu Hui Yang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 3 |
| 20 | Early Cretaceous Climate Changes Recorded in Magnetic Susceptibility and Color Index Variations of the Lower Liupanshan Group, Central China显示文摘This study carried out comprehensive analysis on sedimentology, magnetic susceptibility(χlf) and color data of the continental sediments of the Liupanshan Group in Central China so as to obtain climatic change information during the 129.14–122.98 Ma interval. Based on the results of the ?lf and of the redness(a*), the section can be divided into two segments:(1) 129.14–126.3 Ma, with the lowest ?lf values and strongly variable relatively high values of redness and(2) 126.3–122.98 Ma, with high ?lf values and relatively low redness. Analysis of the lithology and facies as well as the magnetic minerals and their contents points to a detrital origin of the magnetic minerals and this allow us to interpret the relationship between magnetic susceptibility variations and climate changes. Our study shows that the climate was significantly dry and hot during the whole studied interval although the interval between 126.3 Ma and 122.98 was a little bit cooler with increased humidity. | DAI Shuang ZHU Qiang HUANG Yongbo DA SILVA Anne-Christine ZHAO Jie LIU Junwei KONG Li PENG Dongxiang LUO Lingling YAN Ningyun WANG Wenjie ZHANG Xiang | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 3 |
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