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| 1 | Initial study of biexponential model of intravoxel incoherent motion magnetic resonance imaging in evaluation of the liver fibrosis显示文摘 | Chen Cuiyun Wang Bin Shi Dapeng Fu Fangfang Zhang Jiliang Wen Zejun Zhu Shaocheng Xu Junling Lin Qing Li Jing Dou Shewei | 2014 | Chinese Medical Journal2014，，17： | 15 |
| 2 | Expression Analysis of miRNAs and Highly-expressed Small RNAs in Two Rice Subspecies and their Reciprocal Hybrids显示文摘Heterosis,or hybrid vigor,is the phenomenon whereby progeny of two inbred lines exhibit superior agronomic performance compared with either parent.We analyzed the expression of miRNAs and highly expressed small RNAs (defined according to Solexa sequencing results) in two rice (Oryza sativa) subspecies (japonica cv.Nipponbare and indica cv.93-11) and their reciprocal hybrids using microarrays.We found that of all the 1141 small RNAs tested,140 (12%,140 of 1141) and 157 (13%,157 of 1141) were identified being significantly differentially expressed in two reciprocal hybrids,respectively.All possible modes of action,including additive,high-and low-parent,above high-and below low-parent modes were exhibited.Both F1 hybrids showed non-additive expression patterns,with downregulation predominating.Interestingly,15 miRNAs displayed stark opposite expression trends relative to midparent in reciprocal hybrids.Computational prediction of targets of differentially expressed miRNAs showed that they participated in multifaceted developmental pathways,and were not distinguishable from the targets of non-differentially expressed miRNAs.Together,our findings reveal that small RNAs play roles in heterosis and add a new layer in the understanding and exploitation of molecular mechanisms of heterosis. | Fangfang Chen Guangming He Hang He Wei Chen Xiaopeng Zhu Manzhong Liang Liangbi Chen Xing Wang Deng | 2010 | Journal of Integrative Plant Biology2010，52，11： | 10 |
| 3 | Circulating tumor cells:biology and clinical significance显示文摘Circulating tumor cells(CTCs)are tumor cells that have sloughed off the primary tumor and extravasate into and circulate in the blood.Understanding of the metastatic cascade of CTCs has tremendous potential for the identification of targets against cancer metastasis.Detecting these very rare CTCs among the massive blood cells is challenging.However,emerging technologies for CTCs detection have profoundly contributed to deepening investigation into the biology of CTCs and have facilitated their clinical application.Current technologies for the detection of CTCs are summarized herein,together with their advantages and disadvantages.The detection of CTCs is usually dependent on molecular markers,with the epithelial cell adhesion molecule being the most widely used,although molecular markers vary between different types of cancer.Properties associated with epithelial-tomesenchymal transition and stemness have been identified in CTCs,indicating their increased metastatic capacity.Only a small proportion of CTCs can survive and eventually initiate metastases,suggesting that an interaction and modulation between CTCs and the hostile blood microenvironment is essential for CTC metastasis.Single-cell sequencing of CTCs has been extensively investigated,and has enabled researchers to reveal the genome and transcriptome of CTCs.Herein,we also review the clinical applications of CTCs,especially for monitoring response to cancer treatment and in evaluating prognosis.Hence,CTCs have and will continue to contribute to providing significant insights into metastatic processes and will open new avenues for useful clinical applications. | Danfeng Lin Lesang Shen Meng Luo Kun Zhang Jinfan Li Qi Yang Fangfang Zhu Dan Zhou Shu Zheng Yiding Chen Jiaojiao Zhou | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 8 |
| 4 | Scalable salt-templated directed synthesis of high-quality MoS_(2) nanosheets powders towards energetic and environmental applications显示文摘Two-dimensional(2D)transition metal dichalcogenides(TMDCs)have emerged as perfect platforms for developing applications in nano-electronics,catalysis,energy storage and environmental-related fields due to their superior properties.However,the low-cost,batch production of high-quality 2D TMDCs remains a huge challenge with the existing synthetic strategies.Herein,we present a scalable chemical vapor deposition(CVD)approach for the batch production of high-quality MoS_(2) nanosheet powders,by using naturally abundant,water-soluble and recyclable NaCl crystal powders as templates.The high-quality MoS_(2) nanosheets powders are achieved by a facile water dissolution-filtration process,by virtue of the excellent dispersibility of the as-grown products in water.The internal mechanism for the scalable synthesis strategy is explored.The applications of the MoS_(2) nanosheets powders are also demonstrated as catalysts or adsorbents in hydrogen evolution reaction(HER)and organic dyes adsorption,respectively.This work should hereby pave ways for the mass production and application of powdery TMDCs in energetic and environmental related fields. | Lijie Zhu Pengfei Yang Yahuan Huan Shuangyuan Pan Zhaoqian Zhang Fangfang Cui Yuping Shi Shaolong Jiang Chunyu Xie Min Hong Jiatian Fu Jingyi Hu Yanfeng Zhang | 2020 | Nano Research2020，13，11： | 4 |
| 5 | A Recommendation Mechanism for Web Publishing Based on Sentiment Analysis of Microblog显示文摘Microblog is a social platform with huge user community and mass data. We propose a semantic recommendation mechanism based on sentiment analysis for microblog. Firstly, the keywords and sensibility words in this mechanism are extracted by natural language processing including segmentation, lexical analysis and strategy selection. Then, we query the background knowledge base based on linked open data(LOD) with the basic information of users. The experiment result shows that the accuracy of recommendation is within the range of 70%-89% with sentiment analysis and semantic query. Compared with traditional recommendation method, this method can satisfy users' requirement greatly. | TIAN Pingfang ZHU Zhonghua XIONG Li XU Fangfang | 2015 | Wuhan University Journal of Natural Sciences2015，20，2： | 2 |
| 6 | A compact polarization-integrated long wavelength infrared focal plane array based on In As/GaSb superlattice显示文摘Real-time polarization imaging plays a vital role in target detection,recognition,and tracking in complex scenes.However,large optical crosstalk and the integration technology are difficult problems in the development of polarization-integrated infrared detectors.We demonstrate a monolithic long wavelength infrared(LWIR)In As/Ga Sb superlattice focal plane array(FPA)integrated with the polarizer.To obtain high performance and real-time polarization imaging devices,the parameters of the grating were optimized and the optical crosstalk between adjacent polarization bands was studied.We analyze the light diffraction depending on the distance between the polarizer and photosensitive elements and the coupling between oblique incident light and device.The fabrication process of the antireflective polarizer,the integration technology of the polarizer and the FPA composed of 512×4×3 pixels were explored.Finally,a polarization integrated focal plane array(PI-FPA)was fabricated to detect polarized light with different oscillating directions.The large response extinction ratio of corresponding polarization bands was measured as 50:1,49:1,and 44:1 of 0°,60°,and 120°,respectively. | Jian ZHOU Yi ZHOU Ying SHI Fangfang WANG Zhicheng XU Zhizhong BAI Min HUANG Lulu ZHENG Zhaoming LIANG Yihong ZHU Qingqing XU Yiming SHEN Xiangxiao YING Jianxin CHEN | 2022 | Science China(Information Sciences)2022，65，2： | 2 |
| 7 | Heteroepitaxial growth of thick α-Ga_2O_3 film on sapphire(0001)by MIST-CVD technique显示文摘The 8 μm thick single-crystalline α-Ga2O3 epilayers have been heteroepitaxially grown on sapphire(0001) substrates via mist chemical vapor deposition technique. High resolution X-ray diffraction measurements show that the full-widths-at-halfmaximum(FWHM) of rocking curves for the(0006) and(10-14) planes are 0.024° and 0.24°, and the corresponding densities of screw and edge dislocations are 2.24 × 106 and 1.63 × 109 cm-2, respectively, indicative of high single crystallinity. The out-ofplane and in-plane epitaxial relationships are [0001] α-Ga2O3//[0001] α-Al2O3 and [11-20] α-Ga2O3//[11-20] α-Al2O3, respectively.The lateral domain size is in micron scale and the indirect bandgap is determined as 5.03 eV by transmittance spectra. Raman measurement indicates that the lattice-mismatch induced compressive residual strain cannot be ruled out despite the large thickness of the α-Ga2O3 epilayer. The achieved high quality α-Ga2O3 may provide an alternative material platform for developing high performance power devices and solar-blind photodetectors. | Tongchuan Ma Xuanhu Chen Fangfang Ren Shunming Zhu Shulin Gu Rong Zhang Youdou Zheng Jiandong Ye | 2019 | Journal of Semiconductors2019，40，1： | 2 |
| 8 | Modelling the impact of sea-level rise on urban flood probability in SE China显示文摘Urban drainage systems in coastal cities in SE China are characterized by often complex canal and sluicegate systems that are designed to safely drain pluvial flooding whilst preventing tidal inundation.However, the risk of coastal flooding in the region is expected to increase over the next 50-100 years, as urban areas continue to expand and sea-levels are expected to rise. To assess the impact of projected sealevel rise on this type of urban drainage system, a one-dimensional model and decision support tool was developed. The model indicated that although sea-level rise represents a significant challenge, flood probability will continue to be most influenced by rainfall. Events that are significant enough to cause flooding will most likely be minimally impacted by changes to the tidal frame. However, it was found that a sea-level rise of up to 1.2 m by 2010 would result in increased drainage times and higher volumes of over-topping when flooding occurs. | James Andrew Griffiths Fangfang Zhu Faith Ka Shun Chan David Laurence Higgitt | 2019 | Geoscience Frontiers2019，10，2： | 2 |
| 9 | Effective doctor-patient communication skills training optimizes functional organization of intrinsic brain architecture:a restingstate functional MRI study显示文摘We studied the influence of doctor-patient communication skills training on brain functional architecture using resting-state functional MRI(rs-fMRI) with a regional homogeneity(ReHo) method. Ten medical students participated in the study. A 1-year long doctor-patient communication skills training program was conducted. RsfMRI data were collected at baseline, one month and one year after training. There was a significant increase in the communication skills test average scores between baseline and 1-month duration of training(P<0.001). After one month of communication skills training, medical students had decreased ReHo in the right superior temporal gyrus compared with the baseline. After one year of communication skills training, students had increased ReHo in multiple regions and decreased ReHo in several regions(P <0.05, Alphasim corrected). The change of ReHo values in the superior temporal gyrus negatively correlated with the change of communication skills scale score between one month after communication skills training and baseline(r=-0.734, P= 0.036). The training program we used can be an effective approach of improving doctor-patient communication skills, and the training resulted in functional plasticity of the brain's architecture toward optimizing locally functional organization. | Bing Zhang Ling Ni Fangfang Wang Weiping Li Xin Zhang Xiaohua Gu Zuzana Nedelska Fei Chen Kun Wang Bin Zhu Renyuan Liu Jun Xu Jinfan Wang | 2017 | The Journal of Biomedical Research2017，31，6： | 2 |
| 10 | Impacts of land disturbance and restoration on runoff production and sediment yield in the Chinese Loess Plateau显示文摘Land disturbance and land restoration are important factors influencing runoff production and sediment yield in the semi-arid loess regions of China. This study compared the runoff production and sediment yield during the early stage after land disturbance(ESLD) with those during restoring stage after land disturbance(RSLD). Grey relational analysis was used to analyse the importance of each one of the influencing factors(vegetation, rainfall, soil and topography) in affecting the runoff production and sediment yield. Our results showed that during ESLD, topography was the most critical factor controlling the runoff production, while soil was the most important factor controlling the sediment yield. During RSLD, vegetation was more important in affecting runoff production, while rainfall was more important in affecting sediment yield. In additional, this study demonstrated that both the runoff production and the sediment yield can be effectively reduced by restoring vegetation on severely-disturbed lands, thus providing an important theoretical basis for better implementations of the Grain for Green Program. Our results revealed that the vegetation types of Hippophae rhamnoides+Pinus tabulaeformis and H. rhamnoides are better plant selections for land restoration in this area, especially for relatively gentle slopes(i.e., less than 20 degrees). | AI Ning WEI Tianxing ZHU Qingke QIANG Fangfang MA Huan QIN Wei | 2017 | Journal of Arid Land2017，9，1： | 1 |
| 11 | Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson’s disease显示文摘Background:Blood-based test for predicting disease progression and early diagnosis of Parkinson’s disease(PD)is an unmet need in the clinic.The profiles of microRNAs(miRNAs)are regarded as potential diagnostic biomarkers for human diseases,whereas miRNAs in the periphery are susceptible to the influence of various components.MiRNAs enriched in serum extracellular vesicles(EVs)have demonstrated disease-specific advantages in diagnosis due to their high abundance,stability and resistance to degradation.This study was aimed to screen differentially expressed EV-derived miRNAs between healthy controls and PD patients to aid in diagnosis of PD.Methods:A total of 31 healthy controls and 72 patients with a diagnosis of PD at different Hoehn and Yahr stages in Tangdu Hospital were included.In total,185 differentially expressed miRNAs were obtained through RNA sequencing of serum EVs as well as edgeR and t-test analyses.Subsequently,the weighted gene co-expression network analysis(WGCNA)was utilized to identify the commonly expressed miRNAs in all stages of PD by constructing connections between modules,and specifically expressed miRNAs in each stage of PD by functional enrichment analysis.After aligning these miRNAs with PD-related miRNAs in Human miRNA Disease Database,the screened miRNAs were further validated by receiver operating characteristic(ROC)curves and quantitative real-time polymerase chain reaction(qRT-PCR)using peripheral blood EVs from 40 more participants.Results:WGCNA showed that 4 miRNAs were commonly associated with all stages of PD and 13 miRNAs were specifically associated with different stages of PD.Of the 17 obtained miRNAs,7 were validated by ROC curve analysis and 7 were verified in 40 more participants by qRT-PCR.Six miRNAs were verified by both methods,which included 2 miRNAs that were commonly expressed in all stages of PD and 4 miRNAs that were specifically expressed in different stages of PD.Conclusions:The 6 serum EV-derived miRNAs,hsa-miR-374a-5p,hsa-miR-374b-5p,hsa-miR-199a-3p,hsa-miR-28-5p,hsa-miR-22-5p and hsa-miR-151a-5p,may potentially be used as biomarkers for PD progression and for early diagnosis of PD in populations. | Shulei He Lu Huang Ci Shao Tiejian Nie Li Xia Bozhou Cui Fangfang Lu Lin Zhu Bolin Chen Qian Yang | 2021 | Translational Neurodegeneration2021，10，3： | 1 |
| 12 | Phage-displayed protein chip based on SPR sensing显示文摘 | Fangfang Liu Zhaofeng Luo Xiang Ding Shenggeng Zhu Xinglong Yu | 2008 | Chemical2008，，1： | 1 |
| 13 | HPLC Fingerprint Chromatogram of Tetracera asiatica Produced in Guangxi显示文摘[Objectives] To establish fingerprint chromatogram of Tetracera asiatica and provide basis for controlling and assessing the quality of Tetracera asiatica.[Methods] The high-performance liquid chromatography( HPLC) method was used. Phenomenex C18( 5 μm,4. 6 ×250 mm),acetonitrile-0. 1% phosphoric acid water,gradient elution,flow rate 1 m L/min,detection wavelength 214 nm,and column temperature 25 ℃. The fingerprint chromatogram of 10 batches of samples of Tetracera asiatica was determined for similarity comparison. [Results] It established HPLC fingerprint chromatogram of Tetracera asiatica produced in Guangxi,determined a total of 13 common fingerprint peaks. The similarity of 10 batches of Tetracera asiatica was > 0. 9.[Conclusions] The method is rapid and accurate and can provide references for assessing the quality of Tetracera asiatica. | Fangfang DA Zhonghua DAI Hua ZHU Jianbei TENG | 2017 | Medicinal Plant2017，8，4： | 1 |
| 14 | Removal of antibiotics from aqueous solution by using porous adsorbent templated from eco-friendly Pickering aqueous foams显示文摘The aqueous foam template without any solvent and only using the particles stabilizer has attracted much attention for preparation of the porous adsorbents.Herein,a novel porous adsorbent was fabricated via thermal-initiated polymerization of Pickering aqueous foams,which was stabilized by the natural sepiolite(Sep)and pine pollen,and utilized for the removal of antibiotic from aqueous solution.The stabilizing mechanism of Pickering aqueous foam of that the Sep was modified with the leaching substance from pine pollen and arranged orderly around the bubble to form a dense'shell'structure was revealed.The adsorbents possessed the hierarchical porous structure and excellent adsorption performance for antibiotic of chlorotetracycline hydrochloride(CTC)and tetracycline hydrochloride(TC).The equilibrium adsorption capacities of CTC and TC were achieved with 465.59 and 330.59 mg/g within 60 min at 25℃,respectively.The adsorption process obeyed Langmuir model and pseudo-second-order adsorption kinetic model.This work provided eco-friendly approach for fabricate porous adsorbents for wastewater treatment. | Hui Yu Yongfeng Zhu Aiping Hui Fangfang Yang Aiqin Wang | 2021 | Journal of Environmental Sciences2021，33，4： | 1 |
| 15 | Assessment of respiratory support decision and the outcome of invasive mechanical ventilation in severe COVID-19 with ARDS显示文摘Background:The coronavirus disease 2019(COVID-19)is an ongoing pandemic.Invasive mechanical ventilation(IMV)is essential for the management of COVID-19 with acute respiratory distress syndrome(ARDS).We aimed to assess the impact of compliance with a respiratory decision support system on the outcomes of patients with COVID-19-associated ARDS who required IMV.Methods:In this retrospective,single-center,case series study,patients with COVID-19-associated ARDS who required IMV at Zhongnan Hospital of Wuhan University,China,from January 8th,2020,to March 24th,2020,with the final follow-up date of April 20th,2020,were included.Demographic,clinical,laboratory,imaging,and management information were collected and analyzed.Compliance with the respiratory support decision system was documented,and its relationship with 28-day mortality was evaluated.Results:The study included 46 COVID-19-associated ARDS patients who required IMV.The median age of the 46 patients was 68.5 years,and 31 were men.The partial pressure of arterial oxygen(PaO_(2))/fraction of inspired oxygen(FiO_(2))ratio at intensive care unit(ICU)admission was 104 mmHg.The median total length of IMV was 12.0(interquartile range[IQR]:6.0–27.3)days,and the median respiratory support decision score was 11.0(IQR:7.8–16.0).To 28 days after ICU admission,18(39.1%)patients died.Survivors had a significantly higher respiratory support decision score than non-survivors(15.0[10.3–17.0]vs.8.5(6.0–10.3),P=0.001).Using receiver operating characteristic(ROC)curve to assess the discrimination of respiratory support decision score to 28-day mortality,the area under the curve(AUC)was 0.796(95%confidence interval[CI]:0.657–0.934,P=0.001)and the cut-offwas 11.5(sensitivity=0.679,specificity=0.889).Patients with a higher score(>11.5)were more likely to survive at 28 days after ICU admission(log-rank test,P<0.001).Conclusions:For severe COVID-19-associated ARDS with IMV,following the respiratory support decision and assessing completion would improve the progress of ventilation.With a decision score of>11.5,the mortality at 28 days after ICU admission showed an obvious decrease. | Shuhan Cai Fangfang Zhu Hongtao Hu Hui Xiang Dawei Wang Jing Wang Lu Li Xiao Yang Aihua Qin Xin Rao Yun Luo Jianguo Li Kianoush B.Kashani Bo Hu Zhiyong Peng | 2022 | Journal of Intensive Medicine2022，2，2： | 1 |
| 16 | Seven new 3,4-dihydro-furanocoumarin derivatives from Angelica dahurica显示文摘Objective:To study the chemical constituents of the roots of Angelica dahurica,a well-known Chinese herbal medicine named Baizhi in Chinese.Methods:Compounds were separated by various chromatographies,and the structures of new compounds were elucidated based on the analysis of their spectroscopic and spectrometric data(1D,2D NMR,HRESI MS,IR,and UV).The absolute configurations of new compounds were determined by the calculated electronic circular dichroism and chemical derivatization.The inhibitory activities of all isolates against nitric oxide(NO)production were evaluated using lipopolysaccharide-activated RAW 264.7macrophage cells.Results:Seven new 3,4-dihydro-furanocoumarin derivatives(1a/1b,2a/2b,3a/3b,4)together with a known furanocoumarin(5)were isolated from the roots of A.dahurica.The new compounds included three pairs of enantiomers,(4S,2’’R)-angelicadin A(1a)/(4R,2’’S)-angelicadin A(1b),(4S,2’’S)-angelicadin A(2a)/(4R,2’’R)-angelicadin A(2b),and(4S,2’’S)-secoangelicadin A(3a)/(4R,2’’R)-secoangelicadin A(3b),together with(4R,2’’R)-secoangelicadin A methyl ester(4).The known xanthotoxol(5)inhibited the NO production with the half-maximal inhibitory concentration(IC50)value of(32.8±0.8)μmol/L,but all the new compounds showed no inhibitory activities at the concentration of100μmol/L.Conclusion:This is the first report of the discovery of 3,4-dihydro-furanocoumarins from A.dahurica.The results are not only meaningful for the understanding of the chemical constituents of A.dahurica,but also enrich the reservoir of natural products. | Yang Wang Fanyu Shi Zihan Lu Mingliang Zhang Zekun Zhang Fangfang Jia Beibei Zhang Lishan Ouyang Zhixiang Zhu Shepo Shi | 2023 | Chinese Herbal Medicines2023，15，3： | 1 |
| 17 | Pt-Ru Catalysts Prepared by a Modified Polyol Process for Direct Methanol Fuel Cells显示文摘Supported PtRu/C catalysts used in direct methanol fuel cells (DMFCs) were prepared by a new modified polyol method. Transmission electron microscopy (TEM), X-ray diffraction (XRD) and cyclic voltammograms (CVs) were carried out to characterize the morphology, composition and the electrochemical properties of the PtRu/C catalyst. The results revealed that the PtRu nanoparticles with small average particle size (≈2.5 nm), and highly dispersed on the carbon support. The PtRu/C catalyst exhibited high catalytic activity and anti poisoned performance than that of the JM PtRu/C. It is imply that the modified polyol method is efficient for PtRu/C catalyst preparation. | ZHANG Junmin ZHU Fangfang ZHANG Kunhua LIU Weiping GUAN Weiming | 2012 | 贵金属2012，33，A01： | 1 |
| 18 | Gaussian decomposition and component pigment spectral analysis of phytoplankton absorption spectra显示文摘The absorption spectrum of phytoplankton is an important bio-optical parameter for ocean color hyperspectral remote sensing;its magnitude and shape can be aff ected considerably by pigment composition and concentration. We conducted Gaussian decomposition to the absorption spectra of phytoplankton pigment and studied the spectral components of the phytoplankton, in which the package effect was investigated using pigment concentration data and phytoplankton absorption spectra. The decomposition results were compared with the corresponding concentrations of the five main pigment groups (chlorophylls a , b , and c , photo-synthetic carotenoids (PSC), and photo-protective carotenoids (PPC)). The results indicate that the majority of residual errors in the Gaussian decomposition are <0.001 m^-1 , and R 2 of the power regression between characteristic bands and HPLC pigment concentrations (except for chlorophyll b) was 0.65 or greater for surface water samples at autumn cruise. In addition, we determined a strong predictive capability for chlorophylls a , c , PPC, and PSC. We also tested the estimation of pigment concentrations from the empirical specific absorption coeffi cient of pigment composition. The empirical decomposition showed that the Ficek model was the closest to the original spectra with the smallest residual errors.The pigment decomposition results and HPLC measurements of pigment concentration are in a high consistency as the scatter plots are distributed largely near the 1:1 line in spite of prominent seasonal variations. The Wozniak model showed a better fit than the Ficek model for Ch1 a , and the median relative error was small. The pigment component information estimated from the phytoplankton absorption spectra can help better remote sensing of hyperspectral ocean color that related to the changes in phytoplankton communities and varieties. | YE Huping ZHANG Bing LIAO Xiaohan LI Tongji SHEN Qian ZHANG Fangfang ZHU Jianhua LI Junsheng | 2019 | Journal of Oceanology and Limnology2019，37，5： | 1 |
| 19 | Summertime CO_2 fluxes from tundra of Ny-?lesund in the High Arctic显示文摘The Arctic ecosystem, especially High Arctic tundra, plays a unique role in the global carbon cycle because of amplified warming in the region. However, relatively little research has been conducted in High Arctic tundra compared with other global ecosystems. In the present work, summertime net ecosystem exchange(NEE), ecosystem respiration(ER), and photosynthesis were investigated at six tundra sites(DM1–DM6) on Ny-?lesund in the High Arctic. NEE at the tundra sites varied between a weak sink and strong source(-3.3 to 19.0 mg CO_2·m^(-2)·h^(-1)). ER and gross photosynthesis were 42.8 to 92.9 mg CO_2·m^(-2)·h^(-1) and 54.7 to 108.7 mg CO_2·m^(-2)·h^(-1), respectively. The NEE variations showed a significant correlation with photosynthesis rates, whereas no significant correlation was found with ecosystem respiration, indicating that NEE variations across the region were controlled by differences in net uptake of CO_2 owing to photosynthesis, rather than by variations in ER. A Q_(10) value of 1.80 indicated weak temperature sensitivity of tundra ER and its response to future global warming. NEE and gross photosynthesis also showed relatively strong correlations with C/N ratio. The tundra ER, NEE, and gross photosynthesis showed variations over slightly waterlogged wetland tundra, mesic and dry tundra. Overall, soil temperature, nutrients and moisture can be key effects on CO_2 fluxes, ecosystem respiration, and NEE in the High Arctic. | LI Fangfang ZHU Renbin BAO Tao WANG Qing XU Hua | 2017 | Advances in Polar Science2017，28，1： | 1 |
| 20 | Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation显示文摘 | Yang Zhao Xiaolei Yin Han Qin Fangfang Zhu Haisong Liu Weifeng Yang Qiang Zhang Chengang Xiang Pingping Hou Zhihua Song Yanxia Liu Jun Yong Pengbo Zhang Jun Cai Meng Liu Honggang Li Yanqin Li Xiuxia Qu Kai Cui Weiqi Zhang Tingting Xiang Yetao Wu Yiding Zh | 2008 | Cell Stem Cell2008，，5： | 1 |
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