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| 1 | Review of gallium-oxide-based solar-blind ultraviolet photodetectors显示文摘Solar-blind photodetectors are of great interest to a wide range of industrial, civil, environmental, and biological applications. As one of the emerging ultrawide-bandgap semiconductors, gallium oxide(Ga_2O_3) exhibits unique advantages over other wide-bandgap semiconductors, especially in developing high-performance solar-blind photodetectors. This paper comprehensively reviews the latest progresses of solar-blind photodetectors based on Ga_2O_3 materials in various forms of bulk single crystal, epitaxial films, nanostructures, and their ternary alloys.The basic working principles of photodetectors and the fundamental properties and synthesis of Ga_2O_3, as well as device processing developments, have been briefly summarized. A special focus is to address the physical mechanism for commonly observed huge photoconductive gains. Benefitting from the rapid development in material epitaxy and device processes, Ga_2O_3-based solar-blind detectors represent to date one of the most prospective solutions for UV detection technology towards versatile applications. | XUANHU CHEN FANGFANG REN SHULIN GU JIANDONG YE | 2019 | Photonics Research2019，7，4： | 22 |
| 2 | Slicing Recognition of Aircraft Integral Panel Generalized Pocket显示文摘自动地在数字控制(NC ) 获得一个用机器制造的区域编程,概括衣袋的一个数据模型被分析飞机积分面板特征,和一条特征识别途径建立被建议。由一块飞机积分面板的实际用机器制造片的进程的参考,首先,部分和空白在 Z 轴方向被切;因此特征侧面根据切的飞机被创造,轮廓被切的飞机的交叉与部分和它的空白形成。第二,概括衣袋的辅助特征也基于脸类型和位置被决定,到改正衣袋的侧面。最后,概括袖珍特征关系树被在特征之中匹配垂直关系构造。用机器制造使用这个方法生产的特征信息能直接被用来计算切割器路径。方法的有效性和有实行可能被 NC 编程为飞机面板验证。 | Yu Fangfang DU Baorui Ren Wenjie Zheng Guolei Chu Hongzhen | 2008 | Chinese Journal of Aeronautics2008，21，6： | 15 |
| 3 | Development and validation of a questionnaire-based risk scoring system to identify individuals at high risk for gastric cancer in Chinese populations显示文摘Objective:This study aimed to develop and validate a risk scoring system to identify high-risk individuals carrying malignant lesions in stomach for tailored gastric cancer screening.Methods:A gastric cancer risk scoring system(GC-RSS)was developed based on questionnaire-based predictors for gastric cancer derived from systematic literature review.To assess the capability of this system for discrimination,risk scores for 8,214 and 7,235 outpatient subjects accepting endoscopic examination in two endoscopy centers,and 32,630 participants in a community-based cohort in China were calculated to plot receiver operating characteristic curves and generate area under the curve(AUC).To evaluate the performance of GC-RSS,the screening proportion,sensitivity and detection rate ratio compared to universal screening were used under different risk score cutoff values.Results:GC-RSS comprised nine predictors including advanced age,male gender,low body mass index(<18.5 kg/m^(2)),family history of gastric cancer,cigarette smoking,consumption of alcohol,preference for salty food,irregularity of meals and consumption of preserved food.This tool performed well in determining the risk of malignant gastric lesions with AUCs of 0.763,0.706 and 0.696 in three validation sets.When subjects with risk scores≥5 were evaluated with endoscopy,nearly 50%of these endoscopies could be saved with a detection rate of over 1.5 times achieved.When the cutoff was set at 8,only about 10%of subjects with the highest risk would be offered endoscopy,and detection rates for gastric cancer could be increased 2-4 fold compared to universal screening.Conclusions:An effective questionnaire-based GC-RSS was developed and validated.This tool may play an important role in establishing a tailored screening strategy for gastric cancer in China. | Ren Zhou Hongchen Zheng Mengfei Liu Zhen Liu Chuanhai Guo Hongrui Tian Fangfang Liu Ying Liu Yaqi Pan Huanyu Chen Zhe Hu Hong Cai Zhonghu He Yang Ke | 2021 | Chinese Journal of Cancer Research2021，33，6： | 3 |
| 4 | Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration显示文摘在果蝇成年 midgut 的肠的干细胞(ISC ) 为维持织物动态平衡是必要的,并且他们的增长和区别加快以便为填满遇见需求响应损害的失去的房间。包括 JAK-STAT, EGFR 和河马(Hpo ) 小径的几个发信号小径在导致损坏的 ISC 增长被含有,但是集成这些小径的机制留下了逃犯。这里,我们证明 oncoprotein Myc (dMyc ) 的果蝇相当或相同的事物这些下游地工作表明小径调停他们 ISC 增长上的效果。在先锋房间的 dMyc 表示响应织物损坏被刺激,并且 dMyc 为加速的 ISC 增长和 midgut 新生是必要的。我们证明葡聚糖硫酸盐钠喂引起的那织物损坏经由 Hpo 小径刺激 dMyc 表示,而喂的 bleomycin 通过 JAK-STAT 和 EGFR 小径激活 dMyc。我们提供 dMyc 表示是的证据 transcriptionally 由多重发信号的小径的 upregulated,它响应织物为最佳的 ISC 增长被要求损坏。我们也获得了证据那织物损坏罐头 upregulate dMyc 表情 post-transcriptionally。最后,我们证明 dMyc 表示的基础水平在正常织物动态平衡期间为 ISC 维护,增长和系区别被要求。 | Fangfang Ren Qing Shi Yongbin Chen Alice Jiang Y Tony Ip Huaqi Jiang Jin Jiang | 2013 | Cell Research2013，23，9： | 2 |
| 5 | Copper‑Based Catalysts for Electrochemical Carbon Dioxide Reduction to Multicarbon Products显示文摘Electrochemical conversion of carbon dioxide into fuel and chemicals with added value represents an appealing approach to reduce the greenhouse effect and realize a carbon-neutral cycle,which has great potential in mitigating global warming and effectively storing renewable energy.The electrochemical CO_(2) reduction reaction(CO_(2)RR)usually involves multiproton coupling and multielectron transfer in aqueous electrolytes to form multicarbon products(C_(2+) products),but it competes with the hydrogen evolution reaction(HER),which results in intrinsically sluggish kinetics and a complex reaction mechanism and places higher requirements on the design of catalysts.In this review,the advantages of electrochemical CO_(2) reduction are briefly introduced,and then,different categories of Cu-based catalysts,including monometallic Cu catalysts,bimetallic catalysts,metal-organic frameworks(MOFs)along with MOF-derived catalysts and other catalysts,are summarized in terms of their synthesis method and conversion of CO_(2) to C2+products in aqueous solution.The catalytic mechanisms of these catalysts are subsequently discussed for rational design of more efficient catalysts.In response to the mechanisms,several material strategies to enhance the catalytic behaviors are proposed,including surface facet engineering,interface engineering,utilization of strong metal-support interactions and surface modification.Based on the above strategies,challenges and prospects are proposed for the future development of CO_(2)RR catalysts for industrial applications. | Fangfang Chang Meiling Xiao Ruifang Miao Yongpeng Liu Mengyun Ren Zhichao Jia Dandan Han Yang Yuan Zhengyu Bai Lin Yang | 2022 | Electrochemical Energy Reviews2022，5，3： | 2 |
| 6 | Heteroepitaxial growth of thick α-Ga_2O_3 film on sapphire(0001)by MIST-CVD technique显示文摘The 8 μm thick single-crystalline α-Ga2O3 epilayers have been heteroepitaxially grown on sapphire(0001) substrates via mist chemical vapor deposition technique. High resolution X-ray diffraction measurements show that the full-widths-at-halfmaximum(FWHM) of rocking curves for the(0006) and(10-14) planes are 0.024° and 0.24°, and the corresponding densities of screw and edge dislocations are 2.24 × 106 and 1.63 × 109 cm-2, respectively, indicative of high single crystallinity. The out-ofplane and in-plane epitaxial relationships are [0001] α-Ga2O3//[0001] α-Al2O3 and [11-20] α-Ga2O3//[11-20] α-Al2O3, respectively.The lateral domain size is in micron scale and the indirect bandgap is determined as 5.03 eV by transmittance spectra. Raman measurement indicates that the lattice-mismatch induced compressive residual strain cannot be ruled out despite the large thickness of the α-Ga2O3 epilayer. The achieved high quality α-Ga2O3 may provide an alternative material platform for developing high performance power devices and solar-blind photodetectors. | Tongchuan Ma Xuanhu Chen Fangfang Ren Shunming Zhu Shulin Gu Rong Zhang Youdou Zheng Jiandong Ye | 2019 | Journal of Semiconductors2019，40，1： | 2 |
| 7 | Modulation space estimates for damped fractional wave equation显示文摘Instead of the L^p estimates,we study the modulation space estimates for the solution to the damped wave equation.Decay properties for both the linear and semilinear equations are obtained.The estimates in modulation space differ in many aspects from those in L^p space. | ZHANG ChunJie ZHANG YuHuai REN FangFang | 2016 | Science China Mathematics2016，59，4： | 1 |
| 8 | Novel graphene flowers modified carbon fibers for simultaneous determination of ascorbic acid, dopamine and uric acid显示文摘 | DU Jiao YUE Ruirui REN Fangfang | 2014 | Biosensors and Bioelectronics2014，53，： | 1 |
| 9 | Protein N-myristoylation:functions and mechanisms in control of innate immunity显示文摘Protein N-myristoylation is an important fatty acylation catalyzed by N-myristoyltransferases(NMTs),which are ubiquitous enzymes in eukaryotes.Specifically,attachment of a myristoyl group is vital for proteins participating in various biological functions,including signal transduction,cellular localization,and oncogenesis.Recent studies have revealed unexpected mechanisms indicating that protein N-myristoylation is involved in host defense against microbial and viral infections.In this review,we describe the current understanding of protein N-myristoylation(mainly focusing on myristoyl switches)and summarize its crucial roles in regulating innate immune responses,including TLR4-dependent inflammatory responses and demyristoylation-induced innate immunosuppression during Shigella flexneri infection.Furthermore,we examine the role of myristoylation in viral assembly,intracellular host interactions,and viral spread during human immunodeficiency virus-1(HIV-1)infection.Deeper insight into the relationship between protein N-myristoylation and innate immunity might enable us to clarify the pathogenesis of certain infectious diseases and better harness protein N-myristoylation for new therapeutics. | Bin Wang Tong Dai Wenhuan Sun Yujun Wei Jiang Ren Long Zhang Mengdi Zhang Fangfang Zhou | 2021 | Cellular & Molecular Immunology2021，18，4： | 1 |
| 10 | The TEAD/ TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control 显示文摘 | Zhang Lei Ren Fangfang Zhang Qing | 2008 | Dev Cell2008，14，3： | 1 |
| 11 | Comprehensive Humoral and Cellular Immune Responses to SARS-CoV-2 Variants in Diverse Chinese Population显示文摘The SARS-CoV-2 variants have been emerging and have made great challenges to current vaccine and pandemic control strategies.It is urgent to understand the current immune status of various Chinese populations given that the preexisting immunity has been established by national vaccination or ex posure to past variants.Using sera from 85 individuals(including 21 convalescents of natural infection,15 cases which suffered a breakthrough infection after being fully vaccinated,and 49 healthy vaccinees),we showed signifcantly enhanced neutralizing activities against SRAS-CoV-2 variants in convalescent sera,especially those who had been fully vaccinated.The neut ralizing antibodies against Omicron were detectable in 75%of convalescents and 4.9%of healthy vaccinees(p=0.006),with a GMT of 289.5,180.9-463.3,and 42.6,31.3-59,respetively.However,the neutralizing activities were weaker in young convalescents(aged<18y),with a detectable rate of 50%and a GMT of 46.4 against Omicron.We also examined and found no pan.sarbecovirus neutralizing activities in vaccinated SARS-CoV-I survivors.A booster dose could further increase the breadth and magnitude of neutralization against WT and variants of concern(VOCs)to different degrees.In addition,we showed that COVID-19-inactivated vaccines can elicit Omicron-specific T-cell responses.The positive rates of ELISpot reactions were 26.7%(4/15)and 43.8%(7/16)in the full vaccination group and the booster vaccination group,respectively,although without statistically significant difference.The neutralizing antibody titers declined while T-cell responses remain consistent over 6 months.These findings will inform the optimization of public health vaccination and intervention strategies to protect diverse populations against SARS-CoV-2 variants.Advances.Breakthrough infection significantly boosted neutralizing activities against SARS-CoV-2 variants a compared to booster immunization with inaclivated vaccine.Vaccine-induced vir us-specific T-cell immunity,on the other hand,may compensate for the shortall.Furthermore,the public health system should target the most vulnerable group due to a poorer protective serological response in both infected and vaccinated adolescents. | Jiwei Li Jing Wu Qiuyue Long Yan'an Wu Xiaoyi Hu Yukun He Mingzheng Jiang Jia Li Lili Zhao Shuoqi Yang Xiaoyong Chen Minghui Wang Jianshi Zheng Fangfang Wu Ruiliang Wu Lihong Ren Liang Bu Houzhao Wang Ke Li Lijuan Fu Guojun Zhang Yali Zheng Zhancheng Gao | 2022 | Research2022，，2： | 1 |
| 12 | Magnesium ion-implantation-based gallium nitride p-i-n photodiode for visible-blind ultraviolet detection显示文摘In this work, a GaN p-i-n diode based on Mg ion implantation for visible-blind UV detection is demonstrated.With an optimized implantation and annealing process, a p-GaN layer and corresponding GaN p-i-n photodiode are achieved via Mg implantation. As revealed in the UV detection characterizations, these diodes exhibit a sharp wavelength cutoff at 365 nm, high UV/visible rejection ratio of 1.2 × 10~4, and high photoresponsivity of 0.35 A/W, and are proved to be comparable with commercially available GaN p-n photodiodes. Additionally, a localized states-related gain mechanism is systematically investigated, and a relevant physics model of electricfield-assisted photocarrier hopping is proposed. The demonstrated Mg ion-implantation-based approach is believed to be an applicable and CMOS-process-compatible technology for GaN-based p-i-n photodiodes. | WEIZONG XU YATING SHI FANGFANG REN DONG ZHOU LINLIN SU QING LIU LIANG CHENG JIANDONG YE DUNJUN CHEN RONG ZHANG YOUDOU ZHENG HAI LU | 2019 | Photonics Research2019，7，8： | 1 |
| 13 | A gradient descent boosting spectrum modeling method based on back interval partial least squares显示文摘 | REN Dong QU Fangfang LYU Ke | 2015 | Neurocomputing2015，162，： | 1 |
| 14 | The TEAD/TEF family of transcription factor Scalloped mediates I-Iippo signaling in organ size control显示文摘 | Zhang Lei Ren Fangfang Zhang Qing | 2008 | Dev Ce112008，14，3： | 1 |
| 15 | β-decay Study of Tz=-3/2Proton-rich Nucleus 29S显示文摘The exotic decay of nuclei far from the stability has recently become a hot topic of nuclear structure research.The nuclide 29S is not well investigated in the A=4n+1,Tz=-3/2series of strong+β-delayed proton precursors.The decay schemes of these nuclei are characterized | ZHONG Fupeng XU Xinxing LIN Chengjian WANG Jiansong LI Zhihuan YANG Lei MA Nanru WANG Dongxi WEN Peiwei SUN Lijie WU Hongyi LUO Diwen WU Chenguang JIANG Ying LIU Yang ZANG Hongliang LIANG Pengfei LI Pengjie LI Xiaojing ZHAO Qingqing SHI Guozhu MA Junbing MA Peng YU Gongming Dipikap Patel BAI Zhen YANG Feng JIA Huiming ZHANG Huanqiao WANG Jianguo YANG Yanyun MA Weihu HU Qiang JIN Shuya ZHOU Xiaohong LI Ren HOU Dongsheng LIU Minliang HU Zhengguo MA Xinwen YANG Weiqing GAO Zhihao DUAN Fangfang YU Yuechao WANG Yufeng WANG Peng ZHOU Qingwu CUI Danteng WANG Xiang HU Liyuan PAN Min ZHANG Gaolong WANG Xiaoyu | 2017 | Annual Report of China Institute of Atomic Energy2017，，1： | 0 |
| 16 | An effective bimetallic oxide catalyst of RuO_(2)-Co_(3)O_(4) for alkaline overall water splitting显示文摘The rational design of effective bifunctional electrocatalysts is of paramount importance for overall water-splitting technology in sustainable energy conversion.Herein,bimetallic oxide catalysts(RuO_(2)-Co_(3)O_(4))derived from Ru combined MOF-derivatives(MOF=metal-organic framework)were demonstrated effective for overall water splitting in an alkaline solution,owing to the combined merits such as the two-dimensional interconnected network structure,the synergetic coupling effects and increased chemical stability.The as-prepared RuO_(2)-Co_(3)O_(4) only requires an overpotential of 260 mV for oxygen evolution and 75 mV for hydrogen evolution at 10 mA/cm^(2) in 1 M KOH solution;a low cell voltage of 1.54 V was required to reach the kinetic current density of 10 mA/cm^(2) for the water electrolysis when supporting on glass carbon electrode,and very good stability for 40 h was observed.Experimental and theoretical results demonstrated the electronic structure optimization of bimetallic RuO_(2)-Co_(3)O_(4) compared to the individual metal oxide,which promoted interface charges redistribution and the d-band center downshift,resulting in increased activity and stability for water-splitting reactions.This work provides a feasible approach for developing bimetallic oxides for application in energy-relevant electrocatalysis reactions. | Fangfang Ren Jiayu Xu Ligang Feng | 2024 | Nano Research2024，17，5： | 0 |
| 17 | Cohort profile: design and methods of the Chinese colorectal, breast, lung, liver, and stomach cancer screening trial(C-BLAST)显示文摘Given the rapid changes in social structure(urbanization),economic structure(industrialization),and demographic structure(population aging)in China,cancer has become a major public health problem1.Extensive evidence has indicated that screening can decrease cancer mortality,particularly among high-risk groups,and several representative national and regional cancer screening programs have been launched in China to cope with the increasing burden of cancer. | Yubei Huang Zhangyan Lyu Yu Zhang Xiaomin Liu Yacong Zhang Ya Liu Chao Sheng Hongyuan Duan Zeyu Fani Chenyang Li Xiao Lin Zhuowei Feng Lu Zheng Zhaoxiang Ye Hong Lu Ying Zhu Dejun Zhou Xi Wei Li Ren Bin Meng Fangfang Song Fengju Song Kexin Chen | 2023 | Cancer Biology & Medicine2023，20，10： | 0 |
| 18 | NONLINEAR LAGRANGIANS FOR NONLINEAR PROGRAMMING BASED ON MODIFIED FISCHER-BURMEISTER NCP FUNCTIONS显示文摘这份报纸为与不平等限制解决非线性的编程问题基于修改 Fischer-Burmeister NCP 功能建议非线性的 Lagrangians。当惩罚参数是时,这个非线性的 Lagrange 算法产生的点的顺序是局部地会聚的集中定理表演不到在问题函数上的一套合适的条件下面的阀值,和错误解决方案跳了,取决于惩罚参数,也被建立。在最佳的答案的非线性的 Lagrangian 麻袋布的条件数字与控制惩罚参数成正比,这被显示出。而且,纸开发与建议非线性的 Lagrangians 联系的双算法。报导的数字结果建议双算法为解决一些非线性的优化问题基于建议非线性的 Lagrangians 是有效的。[从作者抽象] | Yonghong Ren Fangfang Guo Yang Li | 2015 | Journal of Computational Mathematics2015，33，4： | 0 |
| 19 | Somatic mutation landscape of a meningioma and its pulmonary metastasis显示文摘Background:Extracranial metastasis(ENM)of meningiomas is extremely rare,and typically occurs several years after a primary tumor is diagnosed.However,the genetic changes underlying ENM events have not yet been investigated.Case presentation:A 58-year-old male patient was sent to the emergency room of our hospital because of a sudden fall.Magnetic resonance imaging detected a mass at the right frontal sagittal sinus.He underwent tumor resection and recovered well,but post-operative computed tomography revealed three lumps on the right side of his chest.Thoracic surgery was performed to remove two of the lumps.Pathological findings revealed that the brain and lung tumors were grade I meningiomas.The patient received no additional radiation or chemotherapy post-surgery,and there was no sign of tumor recurrence in the brain or progression of the remaining lump in the chest 1 year after surgery.We performed whole exome sequencing of the patient’s blood,primary brain tumor,and lung metastatic tumor tissues to identify somatic genetic alterations that had occurred during ENM.This revealed that a frameshift deletion of the neurofibromin 2 gene likely drove formation of the meningioma.Surprisingly,we found that the brain tumor was relatively homogeneous and contained only one dominant clone;both the pulmonary metastasis and the original brain tumor were derived from the same clone,and no obvious additional driver mutations were detected in the metastatic tumor.Conclusion:Although ENM of meningiomas is very rare,brain tumor cells appear to be more adaptable to tissue microenvironments outside of the central nervous system than was commonly thought. | Yaran Du Ting Lu Song Huang Fangfang Ren Gang Cui Jian Chen | 2018 | Cancer Communications2018，38，1： | 0 |
| 20 | Engineered olfactory system for in vitro artificial nose显示文摘The engineered biomimetic sensors can not only realize the action of organs,but also combine functional materials as in vitro organs by simulating the response of biological organs to different environmental signals.Artificial nose is a concept proposed by imitating biological olfactory system,simulating olfactory nerve cells,olfactory bulb and olfactory cortex through different materials to realize olfactory function.The sensor array used to sense external gas stimulation can be analyzed based on different recognition principles through different original signals such as optics,electricity,electrochemistry and bioelectricity.Furthermore,combined with pattern recognition and microarray technology,artificial nose can be highly integrated with biocompatible and other important properties to achieve in vitro application.The design principle and necessary components of artificial nose are introduced in this paper including sensing structure,recognition system and functional module.At the same time,the potential development prospects of molecular recognition technology,polymer-based materials and microarray integration in artificial nose are prospected. | Tianshi Zhang Wenfei Ren Fangfang Xiao Jiguang Li Baiyi Zu Xincun Dou | 2022 | Engineered Regeneration2022，3，4： | 0 |
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