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| 1 | Prioritizing sustainable development goals and linking them to ecosystem services:A global expert’s knowledge evaluation显示文摘The implementation of strategies to achieve the Sustainable Development Goals(SDGs)is frequently hindered by potential trade-offs between priorities for either environmental protection or human well-being.However,ecosystem services(ES)-based solutions can offer possible co-benefits for SDGs implementation that are often overlooked or underexploited.In this study,we cover this gap and investigate how experts from different countries value the SDGs and relate them with ES.A total of 66 countries participated to the survey,and answers were grouped into three macro-regions:Asia;Europe,North America,and Oceania(ENO);Latin America,Caribbean and Africa(LA).Results show that the most prioritized SDGs in the three macro-regions are usually those related to essential material needs and environmental conditions,such as SDG2(Zero Hunger),SDG1(No Poverty),and SDG6(Clean Water).At a global scale,the number of prioritized synergies between SDGs and ES largely exceeded trade-offs.The highest amount of synergies was observed for SDG1(No Poverty),mainly with SDG2,SDG3(Good Health),SDG5(Gender Equality),and SDG8(Economic Growth).Other major synergies among SDGs include SDG14-15(Life below water-Life on land),SDG5-10(Gender Equity-Reduced Inequality),and SDG1-2(No poverty-Zero Hunger).At a global scale,SDG15,SDG13,SDG14,and SDG6 were closely related to ES like climate regulation,freshwater,food,water purification,biodiversity,and education.SDG11(Sustainable Cities)and SDG3 were also relevant in Asia and in LA,respectively.Overall,this study shows the potential to couple future policies that can implement SDGs’strategies while adopting ES-based solutions in different regions of the world. | Siqi Yang Wenwu Zhao Yanxu Liu Francesco Cherubini Bojie Fu Paulo Pereira | 2020 | Geography and Sustainability2020，1，4： | 9 |
| 2 | Reversible Histone H2B Monoubiquitination Fine-Tunes Abscisic Acid Signaling and Drought Response in Rice显示文摘Histone H2B monoubiquitination (H2Bub1) plays important roles in several physiological and developmental processes, but its roles in the regulation of plant stress responses remain elusive. Here, we report that H2Bub1 is crucially involved in abscisic acid (ABA) signaling and drought response in rice. We found that rice HISTONE MONOUBIQUITINATION2 (OsHUB2), an E3 ligase for H2Bub1, in teracted with OsbZIP46, a key transcription factor regulating ABA signaling and drought response in rice. Genetic analyses suggest that OsHUB2, upregulated by drought and ABA, positively modulates ABA sensitivity and drought resistance. The H2Bub1 levels were in creased in the target genes of OsbZIP46 under the drought stress and ABA treat- merits, which were positively correlated with their increased expression levels. Interestingly, MODD, a reported suppressor of ABA signaling and drought resistance by mediating OsbZIP46 deactivation and degradation, could reduce the H2Bub1 levels in the target genes of OsbZIP46 by recruiting a putative deubiquitinase OsOTLD1 . Suppression of OsOTLD1in vivo resulted in increased H2Bub1 levels and expression of OsbZIP46 target genes. Collectively, these fin dings established an elaborate mecha nism of histone monoubiquitination in the fine-turning of ABA signaling and drought response by balancing H2Bub1 deposition and removal. | Siqi Ma Ning Tang Xu Li Yongjun Xie Denghao Xiang Jie Fu Jianqiang Shen Jun Yang Haifu Tu Xianghua Li Honghong Hu Lizhong Xiong | 2019 | Molecular Plant2019，12，2： | 7 |
| 3 | SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors显示文摘Muta nt isocitrate dehydrog en ase 1(mlDH1)drives tumorigenesis via produci ng on cometabolite R-2-hydroxyglutarate(R-2-HG)across various tumor types.However,mlDHl in hibitors appear only effective in hematological tumors.The therapeutic ben efit in solid tumors remains elusive,likely due to the complex tumor microenvironment.In this study,we discover that R-2-HG produced by IDH1-mutant tumor cells is preferentially imported into vascular endothelial cells and remodels mitochondrial respiration to promote tumor angiogenesis,conferring a therapeutic vulnerability in IDH1-mutant solid tumors.Mechanistically,SLC1 Alz a Na'-depe ndent glutamate tran sporter that is prefere ntially expressed in en dothelial cells,facilitates the in flux of R-2-HG from the tumor microenvironment into the endothelial cells as well as the intracellular trafficking of R-2-HG from cytoplasm to mitochondria.R-2-HG hijacks SLC1A1 to promote mitochondrial Na^(+)/Ca^(2+)exchange,which activates the mitochondrial respiratory chain and fuels vascular en dothelial cell migratio n in tumor an giogenesis.SLC1A1 deficiency in mice abolishes mlDHl-promoted tumor an giogenesis as well as the therapeutic benefit of mlDHl in hibitor in solid tumors.Moreover,we report that HH2301,a newly discovered mlDHl inhibitor,shows promising efficacy in treating IDH1-mutant cholangiocarcinoma in preclinical models.Together,we identify a new role of SLC1A1 as a gatekeeper of R-2-HG-mediated crosstalk between IDH1-mutant tumor cells and vascular en dothelial cells,and dem on strate the therapeutic potential of mlDHl in hibitors in treating IDH1-muta nt solid tumors via disrupting R-2-HG-promoted tumor angiogenesis. | Xiaomin Wang Ziqi Chen Jun Xu Shuai Tang Nan An Lei Jiang Yixiang Zhang Shaoying Zhang Qingli Zhang Yanyan Shen Shijie Chen Xiaojing Lan Ting Wang Linhui Zhai Siyuwei Cao Siqi Guo Yingluo Liu Aiwei Bi Yuehong Chen Xiameng Gai Yichen Duan Ying Zheng Yixian Fu Yize Li Liang Yuan Linjiang Tong Kun Mo Mingcheng Wang Shu-Hai Lin Minjia Tan Cheng Luo Yi Chen Jia Liu Qiansen Zhang Leping Li Min Huang | 2022 | Cell Research2022，32，7： | 2 |
| 4 | The variation of tangential rheological properties caused by shrinkage anisotropy and moisture content gradient in white birch disks 显示文摘 | FU Zongying ZHAO Jingyao HUAN Siqi | 2015 | Holzfors- ehung2015，69，5： | 1 |
| 5 | Single stain hyperspectral imaging for accurate fungal pathogens identification and quantification显示文摘The most widely used method of identification of microbial morphology and structure is microscopy,but it can be difficult to distinguish between pathogens with a similar appearance.Existing fluorescent staining methods require a combination of a variety of fluorescent materials to meet this demand.In this study,unique concentration-dependent fluorescent carbon dots(CDs)were synthesized for the identification and quantification of pathogens.The emission wavelength of the CDs could be tuned spanning the full visible region by virtue of aggregation-induced narrowing of bandgaps.This tunable emission wavelength of the specific concentration response to diverse microbes can be used to distinguish microorganisms with a similar appearance,even in a same genus.A hyperspectral microscopy system was demonstrated to distinguish Aspergillus flavus and A.fumigatus based on the results above.The identification accuracy of the two similar-looking pathogens can be close to 100%,and the relative proportions and spatial distributions can also be profiled from the mixture of the pathogens.This technique can provide a solution to the fast detection of microorganisms and is potentially applicable to a wide range of problems in areas such as healthcare,food preparation,biotechnology,and health emergency. | Yongqiang Zhang Kunxing Liu Jingkun Yu Haifeng Chen Rui Fu Siqi Zhu Zhenqiang Chen Shuangpeng Wang Siyu Lu | 2022 | Nano Research2022，15，7： | 1 |
| 6 | Modeling and flapping vibration suppression of a novel tailless flapping wing micro air vehicle显示文摘This paper establishes and analyzes a high-fidelity nonlinear time-periodic dynamic model and the corresponding state observer for flapping vibration suppression of a novel tailless Flapping Wing Micro Air Vehicle(FWMAV),named NPU-Tinybird.Firstly,a complete modeling of NPU-Tinybird is determined,including the aerodynamic model based on the quasi-steady method,the kinematic and dynamic model about the mechanism of flapping and attitude control,combined with the single rigid body dynamic model.Based on this,a linearized longitudinal pitch dynamic cycle-averaged model is obtained and analyzed through the methods of neural network fitting and system identification,preparing for the design of flapping vibration suppression observer.Flapping vibration is an inherent property of the tailless FWMAV,which arises from the influence of time-periodic aerodynamic forces and moments.It can be captured by attitude and position sensors on the plane,which impairs the flight performance and efficiency of flight controller and actuators.To deal with this problem,a novel state observer for flapping vibration suppression is designed.A robust optimal controller based on the linear quadratic theory is also designed to stabilize the closed-loop system.Simulation results are given to verify the performance of the observer,including the closed loop responses combined with robust optimal controller,the comparison of different parameters of observer and the comparison with several classic methods,such as Kalman filter,H-infinity filter and low-pass filter,which prove that the novel observer owns a fairly good suppression effect on flapping vibration and benefits for the improvement of flight performance and control efficiency. | Siqi WANG Bifeng SONG Ang CHEN Qiang FU Jin CUI | 2022 | Chinese Journal of Aeronautics2022，35，3： | 1 |
| 7 | The Bergman Kernel Function:Explicit Formulas and Zeroes显示文摘 | Boas H P Fu Siqi Straube E J | 1999 | Proc of AMS1999，，2： | 1 |
| 8 | Demand for Urban Quality of Living in China: Evolution in Compensating Land-Rent and Wage-Rate Differentials显示文摘 | Siqi Zheng Yuming Fu Hongyu Liu | 2009 | The Journal of Real Estate Finance and Economics2009，，3： | 1 |
| 9 | Synthesis of M@ TiO2 (M = Au, Pd, Pt) core - shell nanocomposites with tunable photoreactivity显示文摘 | Zhang Nan Liu Siqi Fu Xianzhi | 2011 | The Journal of Physical Chemis- try C2011，115，18： | 1 |
| 10 | Demand for Urban Quality of Living in China: Evolution in Compensating Land-Rent and Wage-Rate Differentials显示文摘 | Siqi Zheng Yuming Fu Hongyu Liu | 2009 | The Journal of Real Estate Finance and Economics2009，，3： | 1 |
| 11 | No tillage outperforms conventional tillage under arid conditions and following fertilization显示文摘Reduced tillage practices present a tool that could sustainably intensify agriculture.The existing literature,however,lacks a consensus on how and when reduced tillage practices should get implemented.We reanalyzed here an extensive dataset comparing how regular tillage practices(i.e.,conventional tillage)impacted yield of eight crops compared to stopping tillage altogether(i.e.,no-tillage practice).We observed that aridity and fertilization favored no tillage over conventional tillage whereas conventional tillage performed better under high fertility settings.We further show that the responses are consistent across the crops.Our reanalysis complements the original and fills a gap in the literature questioning the conditions under which reducing tillage presents a viable alternative to common tillage practices. | Stavros D.Veresoglou Junjiang Chen Xuheng Du Qi Fu QingLiu Geng Chenyan Huang Xilin Huang Nan Hu Yiming Hun Guolin C.Li Zhiman Lin Zhiyu Ma Yuyi Ou Shuo Qi Haitian Qin Yingbo Qiu Xibin Sun Ye Tao YiLing Tian Jie Wang Lingxiao Wu Ziwei Wu Siqi Xie Ao Yang Dan Yang Chen Zeng Ying Zeng RuJie Zhang | 2023 | Soil Ecology Letters2023，5，1： | 1 |
| 12 | Characteristics and discovery significance of the Upper Triassic–Lower Jurassic marine shale oil in Qiangtang Basin,China显示文摘Mesozoic marine shale oil was found in the Qiangtang Basin by a large number of hydrocarbon geological surveys and shallow drilling sampling.Based on systematic observation and experimental analysis of outcrop and core samples,the deposition and development conditions and characteristics of marine shale are revealed,the geochemical and reservoir characteristics of marine shale are evaluated,and the layers of marine shale oil in the Mesozoic are determined.The following geological understandings are obtained.First,there are two sets of marine organic-rich shales,the Lower Jurassic Quse Formation and the Upper Triassic Bagong Formation,in the Qiangtang Basin.They are mainly composed of laminated shale with massive mudstone.The laminated organic-rich shale of the Quse Formation is located in the lower part of the stratum,with a thickness of 50–75 m,and mainly distributed in southern Qiangtang Basin and the central-west of northern Qiangtang Basin.The laminated organic-rich shale of the Bagong Formation is located in the middle of the stratum,with a thickness of 250–350 m,and distributed in both northern and southern Qiangtang Basin.Second,the two sets of laminated organic-rich shales develop foliation,and various types of micropores and microfractures.The average content of brittle minerals is 70%,implying a high fracturability.The average porosity is 5.89%,indicating good reservoir physical properties to the level of moderate–good shale oil reservoirs.Third,the organic-rich shale of the Quse Formation contains organic matters of types II1 and II2,with the average TOC of 8.34%,the average content of chloroform bitumen'A'of 0.66%,the average residual hydrocarbon generation potential(S1+S2)of 29.93 mg/g,and the Ro value of 0.9%–1.3%,meeting the standard of high-quality source rock.The organic-rich shale of the Bagong Formation contains mixed organic matters,with the TOC of 0.65%–3.10%and the Ro value of 1.17%–1.59%,meeting the standard of moderate source rock.Fourth,four shallow wells(depth of 50–250 m)with oil shows have been found in the organic shales at 50–90 m in the lower part of the Bagong Formation and 30–75 m in the middle part of the Quse Formation.The crude oil contains a high content of saturated hydrocarbon.Analysis and testing of outcrop and shallow well samples confirm the presence of marine shale oil in the Bagong Formation and the Quse Formation.Good shale oil intervals in the Bagong Formation are observed in layers 18–20 in the lower part of the section,where the shales with(S0+S1)higher than 1 mg/g are 206.7 m thick,with the maximum and average(S0+S1)of 1.92 mg/g and 1.81 mg/g,respectively.Good shale oil intervals in the Quse Formation are found in layers 4–8 in the lower part of the section,where the shales with(S0+S1)higher than 1 mg/g are 58.8 m thick,with the maximum and average(S0+S1)of 6.46 mg/g and 2.23 mg/g,respectively. | SHEN Anjiang FU Xiaodong ZHANG Jianyong WEI Xuebin HU Anping WANG Jian XIONG Shaoyun FU Xiugen XIE Yuan LIU Siqi LI Xi WANG Xin HE Xunyun QIAO Zhanfeng ZHENG Jianfeng DUAN Junmao | 2023 | Petroleum Exploration and Development2023，50，5： | 0 |
| 13 | Improving Ultrasonic Testing by Using Machine Learning Framework Based on Model Interpretation Strategy显示文摘Ultrasonic testing(UT)is increasingly combined with machine learning(ML)techniques for intelligently identifying damage.Extracting signifcant features from UT data is essential for efcient defect characterization.Moreover,the hidden physics behind ML is unexplained,reducing the generalization capability and versatility of ML methods in UT.In this paper,a generally applicable ML framework based on the model interpretation strategy is proposed to improve the detection accuracy and computational efciency of UT.Firstly,multi-domain features are extracted from the UT signals with signal processing techniques to construct an initial feature space.Subsequently,a feature selection method based on model interpretable strategy(FS-MIS)is innovatively developed by integrating Shapley additive explanation(SHAP),flter method,embedded method and wrapper method.The most efective ML model and the optimal feature subset with better correlation to the target defects are determined self-adaptively.The proposed framework is validated by identifying and locating side-drilled holes(SDHs)with 0.5λcentral distance and different depths.An ultrasonic array probe is adopted to acquire FMC datasets from several aluminum alloy specimens containing two SDHs by experiments.The optimal feature subset selected by FS-MIS is set as the input of the chosen ML model to train and predict the times of arrival(ToAs)of the scattered waves emitted by adjacent SDHs.The experimental results demonstrate that the relative errors of the predicted ToAs are all below 3.67%with an average error of 0.25%,signifcantly improving the time resolution of UT signals.On this basis,the predicted ToAs are assigned to the corresponding original signals for decoupling overlapped pulse-echoes and reconstructing high-resolution FMC datasets.The imaging resolution is enhanced to 0.5λby implementing the total focusing method(TFM).The relative errors of hole depths and central distance are no more than 0.51%and 3.57%,respectively.Finally,the superior performance of the proposed FS-MIS is validated by comparing it with initial feature space and conventional dimensionality reduction techniques. | Siqi Shi Shijie Jin Donghui Zhang Jingyu Liao Dongxin Fu Li Lin | 2023 | Chinese Journal of Mechanical Engineering2023，36，5： | 0 |
| 14 | Roxadustat(FG-4592)pretreatment attenuates folic acid induced kidney injury via mitophagy显示文摘.Hypoxia precondition plays a protective role in tissues injured by oxidative stress.Whether or not mitophagy is involved needs to be explored.In the present study,the acute kidney injury model was established by folic acid(FA)administration.Roxadustat(FG-4592),a stabilizer of hypoxia-inducible factor(HIF)was used 2 days before FA insult to mimic hypoxia precondition.First of all,the results showed a protective effect,in both renal function and morphology with FG-4592 pretreatment.In addition,BNIP3 and FUNDC1,two key players in.receptor-mediated mitophagy,were induced to express with upregulation of HIF-1alpha.Meanwhile the mitochondrial marker translocase of outer mitochondrial membrane 20(TOMM20)and mtDNA decreased,indicating a decline of mitochondrial quality.On the other hand,PGC-lalpha,the master regulator of mitochondrial biogenesis,was detected no statistical significance,which implied that the decline may attribute to more mitophagy rather than less biogenesis.That upregulation of LC3B and downregulation of p62/SQSTM1 further proved the presence of mitophagy. | Zou Yu Li Xue Wang Kaiyue Xing Jia Wan Pengzhi Cong Jing Fu Yuanyuan Song Kexin Deng Siqi Zhai Xiaoyue | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 15 | Leaky Gut Plays a Critical Role in the Pathophysiology of Autism in Mice by Activating the Lipopolysaccharide‑Mediated Toll‑Like Receptor 4-Myeloid Differentiation Factor 88-Nuclear Factor Kappa B Signaling Pathway显示文摘Increased intestinal barrier permeability,leaky gut,has been reported in patients with autism.However,its contribution to the development of autism has not been determined.We selected dextran sulfate sodium(DSS)to disrupt and metformin to repair the intestinal barrier in BTBR T+tf/J autistic mice to test this hypothesis.DSS treatment resulted in a decreased affinity for social proximity;however,autistic behaviors in mice were improved after the administration of metformin.We found an increased affinity for social proximity/social memory and decreased repetitive and anxiety-related behaviors.The concentration of lipopolysaccharides in blood decreased after the administration of metformin.The expression levels of the key molecules in the toll-like receptor 4(TLR4)–myeloid differentiation factor 88(MyD88)–nuclear factor kappa B(NF-κB)pathway and their downstream inflammatory cytokines in the cerebral cortex were both repressed.Thus,“leaky gut”could be a trigger for the development of autism via activation of the lipopolysaccharide-mediated TLR4–MyD88–NF-κB pathway. | Fang Li Haoran Ke Siqi Wang Wei Mao Cexiong Fu Xi Chen Qingqing Fu Xiaori Qin Yonghua Huang Bidan Li Shibing Li Jingying Xing Minhui Wang Wenlin Deng | 2023 | Neuroscience Bulletin2023，39，6： | 0 |
| 16 | Bounded Plurisubharmonic Exhaustion Functions and Levi-flat Hypersurfaces显示文摘 | Siqi FU Mei-Chi SHAW | 2018 | Acta Mathematica Sinica,English Series2018，34，8： | 0 |
| 17 | 3D-printed Lunar regolith simulant-based geopolymer composites with bio-inspired sandwich architectures显示文摘Over time,natural materials have evolved to be lightweight,high-strength,tough,and damage-tolerant due to their unique biological structures.Therefore,combining biological inspiration and structural design would provide traditional materials with a broader range of performance and applications.Here,the application of an ink-based three-dimensional(3D)printing strategy to the structural design of a Lunar regolith simulant-based geopolymer(HIT-LRS-1 GP)was first reported,and high-precision carbon fiber/quartz sand-reinforced biomimetic patterns inspired by the cellular sandwich structure of plant stems were fabricated.This study demonstrated how different cellular sandwich structures can balance the structure–property relationship and how to achieve unprecedented damage tolerance for a geopolymer composite.The results presented that components based on these biomimetic architectures exhibited stable non-catastrophic fracture characteristics regardless of the compression direction,and each structure possessed effective damage tolerance and anisotropy of mechanical properties.The results showed that the compressive strengths of honeycomb sandwich patterns,triangular sandwich patterns,wave sandwich patterns,and rectangular sandwich patterns in the Y-axis(Z-axis)direction were 15.6,17.9,11.3,and 20.1 MPa(46.7,26.5,23.8,and 34.4 MPa),respectively,and the maximum fracture strain corresponding to the above four structures could reach 10.2%,6.7%,5.8%,and 5.9%(12.1%,13.7%,13.6%,and 13.9%),respectively. | Siqi Ma Yuqi Jiang Shuai Fu Peigang He Chengyue Sun Xiaoming Duan Dechang Jia Paolo Colombo Yu Zhou | 2023 | Journal of Advanced Ceramics2023，12，3： | 0 |
| 18 | WC/Co_(7)Fe_(3)heterojunction embedded in N,P co-doped hierarchical carbon enables rechargeable/flexible Zn-air battery显示文摘Rational design and synthesis of bifunctional oxygen electrocatalysts with high activity and stability are key challenges in the development of rechargeable Zn-air batteries(ZABs).In this paper,tungsten carbide(WC)and Co_(7)Fe_(3)embedded in N,P co-doped hierarchical carbon(WC/Co_(7)Fe_(3)-NPHC)was prepared by using zeolite imidazolate frameworks as precursor.Density functional theory demonstrates that the mutual adjustment among the WC,Co_(7)Fe_(3),and N,P co-doped carbon at the three-phase heterojunction interface makes the catalyst possess moderate adsorption strength,and greatly improves the conductivity and electron transfer rate of the catalyst.As a result,the WC/Co_(7)Fe_(3)-NPHC exhibits a low overall oxygen redox potential difference of 0.72 V,while the ZAB assembled by WC/Co_(7)Fe_(3)-NPHC as an air cathode exhibits ultra-long cycle stability of over 550 h.Futhermore,WC/Co_(7)Fe_(3)-NPHC can keep good charge and discharge stability at different bending angles when applied to flexible solid ZAB. | Huimin Mao Xiaobin Liu Siqi Wu Yixin Fu Guishan Liu Guizhong Zhou Lei Wang | 2023 | Nano Research2023，16，2： | 0 |
| 19 | Higher-order optical rabi oscillations显示文摘Rabi oscillations express a phenomenon of periodic conversion between two wave states in a coupled system.The finding of Rabi oscillation has led to important applications in many different disciplines.Despite great progress,it is still unknown whether the Rabi oscillating state can be excited in the framework of the higher-order vector vortex regime.Here,we demonstrate in theory that the higher-order vector vortex light beams can be Rabi oscillating during evolution in an optical coupling system.This new classical oscillating state of light is characterized by a topologically shaped wavefront and coupled with spatially varying polarization.The vector vortex state exhibits a harmonic oscillatory property in the resonant and nonresonant conditions but differs greatly in Rabi oscillating frequencies.During Rabi oscillation,the complex state maintains its topology and intensity profile,while its intrinsic polarization pattern varies adiabatically in a periodic manner.We present an interpretation of the Rabi oscillation of the higher-order wave states in terms of the coupled-mode theory.Furthermore,we reveal a symmetry-protected transition between two Rabi oscillating modes,driven by a slowly varying phase mismatch.This Rabi transition has not been reported in either quantum mechanics or any other physical setting.This work advances the research of Rabi oscillation into the higher-order regime,and it may lead to novel applications in classical and quantum optics. | Guohua Liu Shenhe Fu Siqi Zhu Hao Yin Zhen Li Zhenqiang Chen | 2023 | Fundamental Research2023，3，6： | 0 |
| 20 | India's Adjustment of Foreign Policy and Sino-Indian Relations显示文摘Since the beginning of this year, India has shown a series of marvelous accomplishments in foreign policy, of which, beside dramatic change of relations with, Pakistan, perhaps the most eye-catching is the rapid warm-up of Sino-lndian relations. During | Dao Shulin Ji Zhiye Fu Mengzi Ma Jiali Hu Shisheng Zhang Siqi | 2003 | Contemporary International Relations2003，13，10： | 0 |
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