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| 1 | A Nonresonant Hybridized Electromagnetic-Triboelectric Nanogenerator for Irregular and Ultralow Frequency Blue Energy Harvesting显示文摘As a promising renewable energy source,it is a challenging task to obtain blue energy,which is irregular and has an ultralow frequency,due to the limitation of technology.Herein,a nonresonant hybridized electromagnetic-triboelectric nanogenerator was presented to efficiently obtain the ultralow frequency energy.The instrument adopted the flexible pendulum structure with a precise design and combined the working principle of electromagnetism and triboelectricity to realize the all-directional vibration energy acquisition successfully.The results confirmed that the triboelectric nanogenerator(TENG)had the potential to deliver the maximum power point of about 470μW while the electromagnetic nanogenerator(EMG)can provide 523 mW at most.The conversion efficiency of energy of the system reached 48.48%,which exhibited a remarkable improvement by about 2.96 times,due to the elastic buffering effect of the TENG with the double helix structure.Furthermore,its ability to collect low frequency wave energy was successfully proven by a buoy in Jialing River.This woke provides an effective candidate to harvest irregular and ultralow frequency blue energy on a large scale. | Weibo Xie Lingxiao Gao Lingke Wu Xin Chen Fayang Wang Daqiao Tong Jian Zhang Jianyu Lan Xiaobin He Xiaojing Mu Ya Yang | 2021 | Research2021，，1： | 4 |
| 2 | Exploration of Approaches and Factors for Healthy City Planning显示文摘Planning and design for healthy cities has drawn increasingly extensive attention. On the one hand, urban environmental issues have become prominent, especially air pollution caused by industrialization in developing countries; on the other hand, urban residents' demand for physical and mental health calls for physical space to promote the quality of life. Based on theoretical and empirical researches, this paper explores significant environmental factors in healthy city planning and their correlation with public health in different approaches. The research discusses the correlations between planning factors and public health from four aspects including land use, spatial form, transportation modes, and green open space so as to reduce pollution and its impact on humans as well as how they encourage physical activity. It aims to provide basis for healthy city planning and its related studies. | Wang Lan Liao Shuwen Zhao Xiaojing Qian Fang | 2018 | China City Planning Review2018，27，1： | 3 |
| 3 | SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors显示文摘Muta nt isocitrate dehydrog en ase 1(mlDH1)drives tumorigenesis via produci ng on cometabolite R-2-hydroxyglutarate(R-2-HG)across various tumor types.However,mlDHl in hibitors appear only effective in hematological tumors.The therapeutic ben efit in solid tumors remains elusive,likely due to the complex tumor microenvironment.In this study,we discover that R-2-HG produced by IDH1-mutant tumor cells is preferentially imported into vascular endothelial cells and remodels mitochondrial respiration to promote tumor angiogenesis,conferring a therapeutic vulnerability in IDH1-mutant solid tumors.Mechanistically,SLC1 Alz a Na'-depe ndent glutamate tran sporter that is prefere ntially expressed in en dothelial cells,facilitates the in flux of R-2-HG from the tumor microenvironment into the endothelial cells as well as the intracellular trafficking of R-2-HG from cytoplasm to mitochondria.R-2-HG hijacks SLC1A1 to promote mitochondrial Na^(+)/Ca^(2+)exchange,which activates the mitochondrial respiratory chain and fuels vascular en dothelial cell migratio n in tumor an giogenesis.SLC1A1 deficiency in mice abolishes mlDHl-promoted tumor an giogenesis as well as the therapeutic benefit of mlDHl in hibitor in solid tumors.Moreover,we report that HH2301,a newly discovered mlDHl inhibitor,shows promising efficacy in treating IDH1-mutant cholangiocarcinoma in preclinical models.Together,we identify a new role of SLC1A1 as a gatekeeper of R-2-HG-mediated crosstalk between IDH1-mutant tumor cells and vascular en dothelial cells,and dem on strate the therapeutic potential of mlDHl in hibitors in treating IDH1-muta nt solid tumors via disrupting R-2-HG-promoted tumor angiogenesis. | Xiaomin Wang Ziqi Chen Jun Xu Shuai Tang Nan An Lei Jiang Yixiang Zhang Shaoying Zhang Qingli Zhang Yanyan Shen Shijie Chen Xiaojing Lan Ting Wang Linhui Zhai Siyuwei Cao Siqi Guo Yingluo Liu Aiwei Bi Yuehong Chen Xiameng Gai Yichen Duan Ying Zheng Yixian Fu Yize Li Liang Yuan Linjiang Tong Kun Mo Mingcheng Wang Shu-Hai Lin Minjia Tan Cheng Luo Yi Chen Jia Liu Qiansen Zhang Leping Li Min Huang | 2022 | Cell Research2022，32，7： | 2 |
| 4 | Investigation on superplasticity of SiC particulate reinforced Aluminum matrix composite act 显示文摘 | Xu Xiaojing Chen Kangmin Cai Lan | 2002 | Metallurgical Sinica2002，38，5： | 1 |
| 5 | Mesenchymal stem cells participate in ex vivi endothelium repair and its effect on vascular smooth muscle growth International显示文摘 | Xiaojing W Lan H Qi Z | 2005 | Journal of Cardiology2005，97，14： | 1 |
| 6 | An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoY-2 variants显示文摘The wide transmission and host adaptation of SARS-CoV-2 have led to the rapid accumulation of mutations,posing significant challenges to the effectiveness of vaccines and therapeutic antibodies.Although several neutralizing antibodies were authorized for emergency clinical use,convalescent patients derived natural antibodies are vulnerable to SARS-CoV-2 Spike mutation. | Xiaojing Chi Xinhui Zhang Shengnan Pan Yanying Yu Yujin Shi Tianli Lin Huarui Duan Xiuying Liu Wenfang Chen Xuehua Yang Lan Chen Xiaoqian Dong Lili Ren Qiang Ding Jianwei Wang Wei Yang | 2022 | Signal Transduction and Targeted Therapy2022，7，3： | 1 |
| 7 | Effect of paclitaxel and mesenchymal stem cells seeding on ex vivo vascular endothelial repair and smooth muscle cells growth 显示文摘 | Xiaojing Wu Lan Huang Qi Zhou | 2005 | J Cardiovasc Pharmacol2005，46，6： | 1 |
| 8 | et al Mesenchymal stem cells participate in ex vivi endothelium repair and its effect on vascular smooth muscle growth显示文摘 | Xiaojing wu Lan huang | 2005 | International Journal of Cardiology2005，97，14： | 1 |
| 9 | Serosurvey for SARS-CoV-2 among blood donors in Wuhan,China from September to December 2019显示文摘The emerging of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)caused COVID-19 pandemic.The first case of COVID-19 was reported at early December in 2019 in Wuhan City,China.To examine specific antibodies against SARS-CoV-2 in biological samples before December 2019 would give clues when the epidemic of SARS-CoV-2 might start to circulate in populations.We obtained all 88,517 plasmas from 76,844 blood donors in Wuhan between 1 September and 31 December 2019.We first evaluated the pan-immunoglobin(pan-Ig)against SARS-CoV-2 in 43,850 samples from 32,484 blood donors with suitable sample quality and enough volume.Two hundred and sixty-four samples from 213 donors were pan-Ig reactive,then further tested IgG and IgM,and validated by neutralizing antibodies against SARS-CoV-2.Two hundred and thirteen samples(from 175 donors)were only pan-Ig reactive,8(from 4 donors)were pan-Ig and IgG reactive,and 43(from 34 donors)were pan-Ig and IgM reactive.Microneutralization assay showed all negative results.In addition,213 screened reactive donors were analyzed and did not show obviously temporal or regional tendency,but the distribution of age showed a difference compared with all tested donors.Then we reviewed SARS-CoV-2 antibody results from these donors who donated several times from September 2019 to June 2020,partly tested in a previous published study,no one was found a significant increase in S/CO of antibodies against SARS-CoV-2.Our findings showed no SARS-CoV-2-specific antibodies existing among blood donors in Wuhan,China before 2020,indicating no evidence of transmission of COVID-19 before December 2019 in Wuhan,China. | Le Chang Lei Zhao Yan Xiao Tingting Xu Lan Chen Yan Cai Xiaojing Dong Conghui Wang Xia Xiao Lili Ren Lunan Wang | 2023 | Protein & Cell2023，14，1： | 0 |
| 10 | VaR Criteria for optimal limited changeloss and truncated change-loss reinsurance显示文摘 | Xiaojing MA Lan WU | 2013 | Frontiers of Mathematics in China2013，8，3： | 0 |
| 11 | Assembling Superfine Bi_(3)TaO_(7) Particles into 2D Fe_(2)O_(3) Nanosheets for Enhanced Usability to Aqueous Tetracycline Residues显示文摘Composites of 2D/0D Fe_(2)O_(3)-Bi_(3)TaO_(7)(FO-BTO)prepared by a hydrothermal method in which superfine Bi_(3)TaO_(7) particles were mounted onto lamellae of Fe_(2)O_(3) sheets could efficiently remove aqueous tetracycline(TC)residues.The optimal composite FO-3BTO had a TC removal rate of 95%in 120 min under solar light,and its overall properties were better than those of reported photocatalysts.According to XRD,HRTEM,XPS,SEM,PL,EIS,and photocurrent tests,Fe_(2)O_(3) and Bi_(3)TaO_(7) composites formed on effective S-scheme heterojunctions,and the tight contact structure contributed to the increase in efficiency of aqueous TC residue removal. | Liu Xiaoqing Cheng Hongjun Wang Zisha Zhang Jian Lan Yanhua Wang Xiaojing | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，2： | 0 |
| 12 | 白血病抑制因子受体反馈上调介导乳腺癌对组蛋白去乙酰化酶抑制剂耐药显示文摘靶向肿瘤表观遗传调控是当前分子靶向抗肿瘤药物研发的重要方向。组蛋白去乙酰化酶(HDAC)抑制剂在表观遗传领域率先取得成功,多个抑制剂被批准上市,用于多种亚型血液肿瘤的临床治疗。 | Hanlin Zeng Jia Qu Nan Jin Jun Xu Chenchu Lin Yi Chen Xinying Yang Xiang He Shuai Tang Xiaojing Lan Xiaotong Yang Ziqi Chen 黄敏 丁健 耿美玉 | 2017 | 科学新闻2017，19，4： | 0 |
| 13 | Expert consensus on difficulty assessment of endodontic therapy显示文摘Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and prevent the root canal system from bacterial reinfection after root canal therapy(RCT). Recent research, encompassing bacterial etiology and advanced imaging techniques, contributes to our understanding of the root canal system’s anatomy intricacies and the technique sensitivity of RCT. Success in RCT hinges on factors like patients, infection severity, root canal anatomy, and treatment techniques. Therefore, improving disease management is a key issue to combat endodontic diseases and cure periapical lesions. The clinical difficulty assessment system of RCT is established based on patient conditions, tooth conditions, root canal configuration, and root canal needing retreatment, and emphasizes pre-treatment risk assessment for optimal outcomes. The findings suggest that the presence of risk factors may correlate with the challenge of achieving the high standard required for RCT. These insights contribute not only to improve education but also aid practitioners in treatment planning and referral decision-making within the field of endodontics. | Dingming Huang Xiaoyan Wang Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Xinmei Chen Jiyao Li Ling Ye Lei Cheng Xin Xu Tao Hu Hongkun Wu Bin Guo Qin Su Zhi Chen Lihong Qiu Wenxia Chen Xi Wei Zhengwei Huang Jinhua Yu Zhengmei Lin Qi Zhang Deqin Yang Jin Zhao Shuang Pan Jian Yang Jiayuan Wu Yihuai Pan Xiaoli Xie Shuli Deng Xiaojing Huang Lan Zhang Lin Yue Xuedong Zhou | 2024 | International Journal of Oral Science2024，16，1： | 0 |
| 14 | Screening for inhibitors against SARS-CoV-2 and its variants显示文摘Severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)continues to evolve,generating new variants that pose a threat to global health;therefore,it is imperative to obtain safe and broad‐spectrum antivirals against SARS‐CoV‐2 and its variants.To this end,we screened compounds for their ability to inhibit viral entry,which is a critical step in virus infection.Twenty compounds that have been previously reported to inhibit SARS‐CoV‐2 replication were tested by using pseudoviruses containing the spike protein from the original strain(SARS‐CoV‐2‐WH01).The cytotoxicity of these compounds was determined.Furthermore,we identified six compounds with strong antagonistic activity against the WH01 pseudovirus,and low cytotoxicity was identified.These compounds were then evaluated for their efficacy against pseudoviruses expressing the spike protein from B.1.617.2(Delta)and B.1.1.529(Omicron),the two most prevalent circulating strains.These assays demonstrated that two phenothiazine compounds,trifluoperazine 2HCl and thioridazine HCl,inhibit the infection of Delta and Omicron pseudoviruses.Finally,we discovered that these two compounds were highly effective against authentic SARS‐CoV‐2 viruses,including the WH01,Delta,and Omicron strains.Our study identified potential broad‐spectrum SARS‐CoV‐2 inhibitors and provided insights into the development of novel therapeutics. | Weijing Yuan Xiaojing Dong Lan Chen Xiaobo Lei Zhuo Zhou Li Guo Jianwei Wang | 2022 | Biosafety and Health2022，4，3： | 0 |
| 15 | Superplasticity of a SiCw/Zn-22Al Composites显示文摘In this paper, the superplastic characteristics of a 15 SiC(vol. Pct) whisker reinforced Zn-22Al alloy composites, fabricated by Iow pressure infiltration and solute treatment after extrusion with the extrusion rate of 10:1, was investigated. The result showed that the composite exhibited a tensile elongation of 150% and a strain rate sensitivity value of about 0.33 at the initial strain rate of 6.67×10-2 s-1 and at 658 K where an appropriate amount of liquid phase was presented in the composite. | Xiaojing XU, Wei WANG and Lan CAISchool of Mechanical Engineering, Jiangsu University, Zhenjiang 212013, China | 2004 | Journal of Materials Science & Technology2004，20，2： | 0 |
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