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| 1 | Monitoring, Warning, and Control of Rockburst in Deep Metal Mines显示文摘 | Xia-Ting Feng Jianpo Liu Bingrui Chen Yaxun Xiao Guangliang Feng Fengpeng Zhang | 2017 | Engineering2017，3，4： | 29 |
| 2 | The impacts of climate change on the Neolithic cultures of Gansu-Qinghai region during the late Holocene Megathermal显示文摘Holocene Megathermal 被划分成早、中间、迟了的时期,各由于他们改变趋势的不同气候在过时的文化上有不同影响。这研究基于在金海·莱克,记录的环境进化信息的比较分析黄土高原和 Zoige 和 Gansu-Qinghai 区域的过时的地点的空间分发的西方的边。结果证明早、中间的时期向温暖、潮湿在 Gansu-Qinghai 区域作为主要扇区与农业支持了过时的文化的开发,而且, Yangshao 文化繁荣的一个全盛时期出现了。Holocene 在 Gansu-Qinghai 区域在 5.9 ka BP 在冷气候事件以后进入了迟了的时期。后来,气候开始变得冷。然而,在 5.84.2 ka BP,相对稳定的温暖、潮湿的气候在这个区域为过时的年龄的 Majiayao 文化的发展创造了条件,因此,它的文化遗产地点的分发向高高度和高纬度膨胀了。从 4.2 ka BP 向前,气候变得冷、干燥,它在 Gansu-Qinghai 区域的过时的文化上有重要影响,在 4.2 ka BP 附近在文化人物和 Qijia 文化的空间分发导致一个戏剧的变化。在以后一将近 300 年冷、干燥的时期,统一过时的耕作文化完全崩溃了。以后,畜牧和耕作和地区性的多重文化的一个工业部门形成了,并且最终导致了原始社会并且开始一个使文明的社会的结束。 | LIU Fenggui ZHANG Yili FENG Zhaodong HOU Guangliang ZHOU Qiang ZHANG Haifeng | 2010 | Journal of Geographical Sciences2010，20，3： | 18 |
| 3 | Community structure and elevational diversity patterns of soil Acidobacteria显示文摘Acidobacteria is one of the most dominant and abundant phyla in soil,and was believed to have a wide range of metabolic and genetic functions. Relatively little is known about its community structure and elevational diversity patterns. We selected four elevation gradients from 1000 to 2800 m with typical vegetation types of the northern slope of Shennongjia Mountain in central China. The vegetation types were evergreen broadleaved forest,deciduous broadleaved forest,coniferous forest and sub-alpine shrubs. We analyzed the soil acidobacterial community composition,elevational patterns and the relationship between Acidobacteria subdivisions and soil enzyme activities by using the 16 S rRNA meta-sequencing technique and multivariate statistical analysis. The result found that 19 known subdivisions as well as an unclassified phylotype were presented in these forest sites,and Subdivision 6 has the highest number of detectable operational taxonomic units(OTUs). A significant single peak distribution pattern(P < 0.05) between the OTU number and the elevation was observed. The Jaccard and Bray–Curtis index analysis showed that the soil Acidobacteria compositional similarity significantly decreased(P < 0.01) with the increase in elevation distance. Mantel test analysis showed the most of the soil Acidobacteria subdivisions had the significant relationship(P < 0.01) with different soil enzymes. Therefore,soil Acidobacteria may be involved in different ecosystem functions in global elemental cycles. Partial Mantel tests and CCA analysis showed that soil pH,soil temperature and plant diversity may be the key factors in shaping the soil Acidobacterial community structure. | Yuguang Zhang Jing Cong Hui Lu Guangliang Li Yuanyuan Qu Xiujiang Su Jizhong Zhou Diqiang Li | 2014 | Journal of Environmental Sciences2014，26，8： | 17 |
| 4 | Mapping coalmine goaf using transient electromagnetic method and high density resistivity method in Ordos City, China显示文摘The research about subsurface characteristics by using transient electromagnetic method(TEM) and high density resistivity method(HDRM) were already conducted in Ordos. The objective of this research is to detect coalmine goaf areas based on rock resistivity. The data processing using wavelet transform, three point smoothing, RES2 DINV and Maxwell processing software to obtain 2D resistivity structure. The results showed that the layers with maximum resistivity values(30e33 U m on Line 1, 30e31 U m on Line 2, 32e40 U m on Line3) are founded at station 1e7, and 14e20 on Line 1,13e18 on Line 2, and 8e13 and 16e20 on Line 3 which is predicted as goaf layer, and the minimum resistivity values(20e26 U m of TEM, 45e75 U m of HDRM) at the other layers. This resistivity difference was caused by the geology and characteristics of the study area which is located close by the cleugh with rich coal, so the goaf area distinguishable with aquifer layer and coal seam. The results were also significant accidents and serious destruction of ecological environment. | Guiju Wu Guangliang Yang Hongbo Tan | 2016 | Geodesy and Geodynamics2016，7，5： | 14 |
| 5 | Characteristics of the lunar samples returned by the Chang'E-5 mission显示文摘Forty-five years after the Apollo and Luna missions returned lunar samples,China's Chang’E-5(CE-5)mission collected new samples from the mid-latitude region in the northeastern Oceanus Procellarum of the Moon.Our study shows that 95%of CE-5 lunar soil sizes are found to be within the range of 1.40-9.35μm,while 95%of the soils by mass are within the size range of 4.84-432.27μm.The bulk density,true density and specific surface area of CE-5 soils are 1.2387 g/cm^(3),3.1952 g/cm^(3) and 0.56 m^(2)/g,respectively.Fragments from the CE-5 regolith are classified into igneous clasts(mostly basalt),agglutinate and glass.A few breccias were also found.The minerals and compositions of CE-5 soils are consistent with mare basalts and can be classified as low-Ti/low-Al/low-K type with lower rare-earth-element contents than materials rich in potassium,rare earth element and phosphorus.CE-5 soils have high FeO and low Mg index,which could represent a new class of basalt. | Chunlai Li Hao Hu Meng-Fei Yang Zhao-Yu Pei Qin Zhou Xin Ren Bin Liu Dawei Liu Xingguo Zeng Guangliang Zhang Hongbo Zhang Jianjun Liu Qiong Wang Xiangjin Deng Caijin Xiao Yonggang Yao Dingshuai Xue Wei Zuo Yan Su Weibin Wen Ziyuan Ouyang | 2022 | National Science Review2022，9，2： | 12 |
| 6 | Studies on the evolution process of rockbursts in deep tunnels显示文摘This paper focuses on the evolution processes of different types of rockbursts occurring in deep tunnels. A series of laboratory tests and in-situ monitoring in deep tunnels excavated by tunnel boring machine (TBM) and drill-and-blast (D&B) method have been conducted to understand the mechanisms and processes of the evolution of different types of rockbursts, including strain rockburst, strain-structure slip rockburst, immediate rockburst and time-delayed rockburst. Three different risk assessment methods are proposed to evaluate the intensity and potential failure depth of rockbursts. These methods can be applied before excavation and the results can be updated according to the real-time information during excavation. Two micro-seismicity based real-time warning systems have been established for predicting various intensities of rockbursts, such as slight, moderate, intensive and extremely intensive rockbursts. Meanwhile, the probability and intensity of the rockburst are also given. The strategy for excavation and support design has been suggested for various intensities of rockbursts before excavation. The strategy for dynamic control of the rockburst evolution process is also proposed according to the monitoring results. The methodology has been successfully applied to rockburst risk reduction for deep tunnels at Jinping II hydropower project. The results have illustrated the applicability of the proposed methodology and techniques concerning rockbursts. | Xiating Feng Bingrui Chen Shaojun Li Chuanqing Zhang Yaxun Xiao Guangliang Feng Hui Zhou Shili Qiu Zhouneng Zhao Yang Yu Dongfang Chen Huajun Ming | 2012 | Journal of Rock Mechanics and Geotechnical Engineering2012，4，4： | 11 |
| 7 | Preliminary results of TiO_2 mapping using Imaging Interferometer data from Chang'E-1显示文摘The distribution of titanium abundance on the lunar surface is important knowledge for lunar geologic studies and future resource utilization.In this paper,we develop a preliminary model based on'ground truths'from Apollo and Luna sample-return sites to produce a titanium abundance map from Chang’E-1 Imaging Interferometer(IIM) images.The derived TiO2 abundances are validated with Clementine UVVIS results in several regions,including lunar highlands neighboring the Apollo 16 landing site,and high-Ti and low-Ti maria near the standard site of Mare Serenitatis(MS2) .The validation results show that TiO2 abundances modeled with Chang’E-1 IIM data are overestimated for highlands(~0.7 wt.%) and low-Ti maria(~1.5 wt.%) and underestimated for high-Ti maria(~0.8 wt.%). | LING ZongCheng ZHANG Jiang LIU JianZhong ZHANG WenXi ZHANG GuangLiang LIU Bin REN Xin MU LingLi LIU JianJun LI ChunLai | 2011 | Chinese Science Bulletin2011，56，20： | 10 |
| 8 | Investigation on the mechanism of aeroelastic hazard during ground test of rocket nozzle显示文摘Side loads and aeroelastic stability of rocket nozzle were studied by solving Navier-Stokes equation coupled with structural equation of motion.The computation was implemented at different total pressure inlet conditions,and flow phenomena of free shock separation(FSS) and restricted shock separation(RSS) were captured.At certain total pressure inlet conditions,it was found that both kinds of separations existed in nozzle flow filed,while RSS exhibited combined space asymmetry and time unsteady characteristics.The corresponding asymmetric circumferential pressure distribution,strong pressure fluctuation in separation region and large range of displacement of shock wave all led to severe side loads.Besides,for flexible nozzles,the low pressure gradient in separation region might reduce structure stability at nozzle exit,resulting in large local deformation.It was also found that aeroelasticity exhibited buffeting characteristic due to the asymmetric separation,resulting in reduction of aeroelastic stability,even structure destruction.Moreover,aeroelasticity might amplify side loads and aggravate its growth rate.However,with increment of inlet pressure,nozzle aeroelastic stability was also increased when a full flow was nearly reached. | LU GuangLiang YE ZhengYin | 2012 | Science China(Technological Sciences)2012，55，9： | 10 |
| 9 | Relative position determination between Chang'E-3lander and rover using in-beam phase referencing显示文摘Chang'E-3 is China's first lunar surface exploration mission, as a part of the second phase of China's Lunar Exploration Program(CLEP). It landed successfully in the northwest of Mare Imbrium on December 14,2013, incorporating two probes, a lander and a rover named Yutu. The execution of the cooperative science tasks required an accurate determination of the relative position between the lander and the rover. In-beam phase referencing experiments have been conducted with the Chinese VLBI Network(CVN) to accurately image the rover in reference to the stationary lander in order to obtain their offsets in Right Ascension and Declination,which were then transformed into the lunar local coordinate system to acquire their relative position on the lunar surface. The observations and the data processing procedures are described in this paper. Images of the rover in six epochs between December 15 and 21, 2013 were made, resulting in accurate positions of the rover that are consistent with the visual localization approach. Through measurement of the locations of the rover's omnidirectional antenna with respect to the lander's directional antenna before their separation, and the recognition of the rover's turning actions during its exploratory moves, we demonstrate that the accuracy of relative position determined in this way could reach the meter level and the resolution is better than 1 m. | ZHOU Huan LI Hai Tao DONG GuangLiang | 2015 | Science China(Information Sciences)2015，58，9： | 9 |
| 10 | Trends of Overweight and Obesity in Yi People between 1996 and 2007:An Yi Migrant Study显示文摘Objective To evaluate trends of overweight and obesity prevalence between 1996 and 2007 in Yi farmers and Yi migrants.Methods An Yi migrant study was conducted in Liangshan Yi Autonomous Prefecture,Sichuan Province,China from 1996 to 2007.Data were collected with identical methods,including standardized questionnaire and body measurements.Results Age‐ and sex‐specific body mass index (BMI) significantly increased from 20.02 in 1996 to 22.36 in 2007,among Yi farmers,which was significantly different from those among Yi migrants (23.67 in 2007 and 20.90 in 1996) (P<0.05).Prevalence of obesity rose from 1.21 % in 1996 to 4.55 % in 2007 (OR=1.15,P<0.001) in Yi migrants,while that in Yi farmers from none in 1996 to 0.12 % in 2007 (P>0.05).Prevalence of overweight rose significantly to 26.24 %in 2007 from 17.24 % in 1996 (OR=1.06,P<0.001) in Yi migrants,while that in Yi farmers from 1.29 % in 1996 to 4.45 % in 2007 (OR=1.14,P<0.001).Yi migrants appeared to have a 5.52‐fold higher risk ondeveloping overweight and obesity than Yi farmers have.Conclusion The Yi migrants had a steeper increase of overweight with year and consequently caused more obesity.Change in lifestyle may contribute most likely to higher prevalence of overweight and obesity in Yi migrants. | SHAN GuangLiang WEI DaYing WANG ChunXiu ZHANG JianHua Wang Bin MA MingJu PAN Li YU Tao XUE Fang WU ZhengLai | 2011 | Biomedical and Environmental Sciences2011，24，5： | 9 |
| 11 | Soil Organic Carbon Contents and Stocks in Coastal Salt Marshes with Spartina alterniflora Following an Invasion Chronosequence in the Yellow River Delta,China显示文摘Plant invasion alters the fundamental structure and function of native ecosystems by affecting the biogeochemical pools and fluxes of materials and energy. Native(Suaeda salsa) and invasive(Spartina alterniflora) salt marshes were selected to study the effects of Spartina alterniflora invasion on soil organic carbon(SOC) contents and stocks in the Yellow River Delta. Results showed that the SOC contents(g/kg) and stocks(kg/m^2) were significantly increased(P < 0.05) after Spartina alterniflora invasion of seven years, especially for the surface soil layer(0–20 cm). The SOC contents exhibited an even distribution along the soil profiles in native salt marshes, while the SOC contents were gradually decreased with depth after Spartina alterniflora invasion of seven years. The natural ln response ratios(Ln RR) were applied to identify the effects of short-term Spartina alterniflora invasion on the SOC stocks. We also found that Spartina alterniflora invasion might cause soil organic carbon losses in a short-term phase(2–4 years in this study) due to the negative Ln RR values, especially for 20–60 cm depth. And the SOCD in surface layer(0–20 cm) do not increase linearly with the invasive age. Spearman correlation analysis revealed that silt + clay content was exponentially related with SOC in surface layer(Adjusted R^2 = 0.43, P < 0.001), suggesting that soil texture could play a key role in SOC sequestration of coastal salt marshes. | ZHANG Guangliang BAI Junhong JIA Jia WANG Xin WANG Wei ZHAO Qingqing ZHANG Shuai | 2018 | Chinese Geographical Science2018，28，3： | 8 |
| 12 | Emergency treatment of 16 patients with necrotizing fasciitis caused by Vibrio vulnificus infection complicated with septic shock显示文摘Necrotizing fasciitis (NF) caused by vibrio vulnificus (VV) is a rare but fatal clinical emergency characterized by hemorrhagic bullous skin lesions,septic shock and multiple organ dysfunction syndrome (MODS),commonly occurring in patients with chronic liver disease.1,2 In general,mortality of these patients is higher than 60%,which could approach 100% when complicated with septic shock.Therefore,early diagnosis and effectively surgical intervention in emergency room are the mainstays for better outcomes of these patients.However,many emergency physicians lack experiences in diagnosing and managing vibrio NF.Furthermore,due to the preexisting severe medical complications including hypotension,lactic acidosis,coagulation disorders and thrombocytopenia,the optimal therapeutic strategies for these critical patients should obviously be evaluated on a patient-to-patient basis,which remains largely undefined. | Hong Guangliang Wu Bin Lu Caijiao Li Mengfang Zhao Guangju Lu Zhongqiu | 2014 | Chinese Medical Journal2014，，10： | 8 |
| 13 | Spatio-temporal Fragmentation of Leisure Activities in Information Era: Empirical Evidence from Nanjing, China显示文摘Activity fragmentation provides a new approach for understanding the transformation of urban space and function in the information era. Numerous theoretical and empirical studies have been conducted on activity fragmentation, but few studies have focused on the fragmentation of leisure activities. This study was intended to extend the extant literature by: 1) analysing the spatio-temporal fragmentation of physical and virtual leisure activities by using a dataset collected in Nanjing, China, and 2) evaluating the reasons of leisure activity fragmentation, as well as the potential spatial effect of activity fragmentation. The results indicated that virtual leisure activities are more fragmented than physical leisure activities, but the fragmentation of physical and virtual leisure activities varies on weekday and weekend, as well as in various locations and urban districts. In addition, the results suggested that sociodemographic factors and information and communication technology(ICT) variables distinctly affect the fragmentation of leisure activities. Meanwhile, the fragmentation of virtual leisure activities may enhance the transformation of traditional urban space by reallocating leisure activity times and locations. | XI Guangliang ZHEN Feng Puel GILLES Fernandez VALERIE | 2017 | Chinese Geographical Science2017，27，1： | 8 |
| 14 | Changes of Biogenic Elements in Phragmites australis and Suaeda salsa from Salt Marshes in Yellow River Delta,China显示文摘Little information is available on biogenic elements(carbon, nitrogen, phosphorus and sulfur) and the ecological stoichiometric characteristics of plants in coastal wetlands. To investigate the contents of carbon, nitrogen, phosphorus and sulfur of plants, and their ecological stoichiometric characteristics in the Yellow(Huanghe) River Delta, plant samples were collected from two typical salt marshes(Suaeda salsa and Phragmites australis wetlands) during the period of from August to October in 2007, and the ratios of C/N, C/P, N/P, C/N/P and C/N/P/S were calculated. Results showed that during the studying period, plant C, N and P were lower than the global average values, and plant N and P were lower than the China's average values. Leaf C and S in Suaeda salsa were significantly lower than those in Phragmites australis(P < 0.05), and leaf N and P in Suaeda salsa and Phragmites australis showed no significant differences(P > 0.05). Average C/N ratios were 23.75 in leaf, 73.36 in stem, 65.67 in root of Suaeda salsa, and 33.77 in leaf, 121.68 in stem, 97.13 in root of Phragmites australis. Average C/N ratios of Suaeda salsa and Phragmites australis were all great than 25, indicating the salt marsh in the Yellow River Delta is an N limitation system. Average C/P ratios were 276.78 in leaf, 709.28 in stem and 1031.32 in root of Suaeda salsa, and 536.94 in leaf, 768.13 in stem and 875.22 in root of Phragmites australis. The average N/P ratios of Suaeda salsa were 12.92 in leaf, 10.77 in stem and 10.91 in root, and the average N/P ratios of Phragmites australis were 16.40 in leaf, 7.40 in stem and 6.92 in root, indicating the Suaeda salsa wetlands were N limited and Phragmites australis wetlands were N limited in August and P limited in October in 2007. The average C/N, C/P and C/N/P ratios in Suaeda salsa and Pragmites australis were higher than the global average values, indicating the lower quality of organic matter provided by wetland plants in the Yellow River delta. | JIA Jia BAI Junhong WANG Wei ZHANG Guangliang WANG Xin ZHAO Qingqing ZHANG Shuai | 2018 | Chinese Geographical Science2018，28，3： | 7 |
| 15 | Data Analysis of Chang'E-1 Gamma-Ray Spectrometer and Global Distribution of U,K,and Th Elemental Abundances显示文摘Gamma 光线分光计(GRS ) 是 Chang'E-1 (CE-1 ) 上的主要收费载重之一月亮的探查,主要试图在月亮的表面上检测元素的丰富和分布。在 03:58 在 2007 年 11 月 28 日,它执行了月亮的 gamma 光线的第一观察。2008 年 10 月 24 日,有效 gamma 光线系列的 2105 h 被 CE-1 GRS 获得了,它盖住月亮的整个表面。这份报纸主要描述处理由使用导出元素的丰富的过程和 CE-1 GRS 时间系列改正了系列的方法的数据:首先,到进为印射的象素的箱数据;然后,执行累积系列的背景扣除并且获得元素的一个山峰区域;并且最后,当模特儿使用元素的丰富倒置生产元素的丰富。在这些上基于比 EPR 在 5s 处理方法, U 的全球丰富地图, K,和 Th。在在 near-EPR 海底山下面的岩浆结晶化压力和融化的条件之间的关联暗示来源吗? | ZOU Yongliao ZHANG Liyan LIU Jianzhong MU Lingli REN Xin ZHANG Guangliang CHANG Jin YAN Jun ZHANG Nan ZHANG Hongbo LU Chang LIU Jianjun ZUO Wei SU Yan WEN Weibin BIAN Wei WANG Min XU Chun LI Chunlai OUYANG Ziyuan | 2011 | Acta Geologica Sinica(English Edition)2011，85，6： | 6 |
| 16 | Thiolated arsenicals in arsenic metabolism: Occurrence,formation, and biological implications显示文摘Arsenic(As) is a notoriously toxic pollutant of health concern worldwide with potential risk of cancer induction, but meanwhile it is used as medicines for the treatment of different conditions including hematological cancers. Arsenic can undergo extensive metabolism in biological systems, and both toxicological and therapeutic effects of arsenic compounds are closely related to their metabolism. Recent studies have identified methylated thioarsenicals as a new class of arsenic metabolites in biological systems after exposure of inorganic and organic arsenicals, including arsenite, dimethylarsinic acid(DMAV), dimethylarsinous glutathione(DMAIIIGS), and arsenosugars. The increasing detection of thiolated arsenicals,including monomethylmonothioarsonic acid(MMMTAV), dimethylmonothioarsinic acid(DMMTAV) and its glutathione conjugate(DMMTAVGS), and dimethyldithioarsinic acid(DMDTAV) suggests that thioarsenicals may be important metabolites and play important roles in arsenic toxicity and therapeutic effects. Here we summarized the reported occurrence of thioarsenicals in biological systems, the possible formation pathways of thioarsenicals, and their toxicity, and discussed the biological implications of thioarsenicals on arsenic metabolism, toxicity, and therapeutic effects. | Yuzhen Sun Guangliang Liu Yong Cai | 2016 | Journal of Environmental Sciences2016，28，11： | 6 |
| 17 | City Networks of Online Commodity Services in China:Empirical Analysis of Tmall Clothing and Electronic Retailers显示文摘City networks have been a critical topic in the fields of urban geography and regional economics. Numerous studies have explored city networks, focusing mainly on infrastructure and industrial networks. Unlike traditional urban network of which the major measuring indexes are population sizes and entity industries, online commodity service networks could reflect well the influencing of emerging economies, especially the Internet economy, on city networks. This study analyzes and reveals structural features of China's city networks through online commodity services, providing the internet economic approach on city networks. Results indicate that the core cities of online commodity service networks are mainly concentrated in eastern coastal areas. In addition, spatial polarization and layer structure of network connections are obvious, descending from the centers in eastern China to peripheral cities in central and western China. Online commodity services of different cities show apparent differences and uncertainties in terms of specialization rates of international connection, which presents a tendency toward diversification. Online commodity service networks are not only associated with goods production, supply, and consumption in physical space but also reflect virtual information, capital, and technology flows, thus providing a new empirical approach for understanding city networks in information and internet economic age. | XI Guangliang ZHEN Feng HE Jinliao GONG Yanhao | 2018 | Chinese Geographical Science2018，28，2： | 6 |
| 18 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 19 | In-situ observations of damage-fracture evolution in surrounding rock upon unloading in 2400-m-deep tunnels显示文摘The damage-fracture evolution of deep rock mass has obvious particularity,which is revealed in 2400-mdeep tunnels by field tests.The evolution of the excavation damaged zone depth is consistent with that of the fractured zone depth.The ratio of the excavation damaged zone depth to the excavation fractured zone depth is greater than 2.0 in a rock mass with both high strength and good integrity,but less than1.5 in a rock mass with lower strength or poor integrity.Zonal disintegration in a rock mass with high strength and fair integrity is more likely to occur when it contains more than two groups of primary fractures in damaged zones.Fractures develop outward in zonal disintegration but are totally different from the single-zone fracture,in which the fractures develop inward,and it is the starting position of the fractured zone when the excavation surface of the middle pilot is 7–9 m close to the pre-set borehole and it stops after the excavation surface of the baseplate is 11–14 m away.The most intense evolution occurs around 2–4 m from the pre-set borehole in the sidewall expansion stage.The research results provide a reference for the monitoring scheme and support design of CJPL-Ⅲin its future construction. | Haosen Guo Qiancheng Sun Guangliang Feng Shaojun Li Yaxun Xiao | 2023 | International Journal of Mining Science and Technology2023，33，4： | 5 |
| 20 | Prevalence, risk factors, and survival associated with pulmonary hypertension and heart failure among patients with underlying coronary artery disease: a national prospective, multicenter registry study in China显示文摘Background: Coronary artery disease (CAD) is the commonest cause of heart failure (HF), whereas pulmonary hypertension (PH) has not been established or reported in this patient population. Therefore, we assessed the prevalence, risk factors, and survival in CAD-associated HF (CAD-HF) complicated with PH.Methods: Symptomatic CAD-HF patients were continuously enrolled in this prospective, multicenter registry study. Echocardiography, coronary arteriography, left and right heart catheterization (RHC), and other baseline clinical data were recorded. Patients were followed up and their survival was recorded.Results: One hundred and eighty-two CAD-HF patients were enrolled, including 142 with HF with a preserved ejection fraction (heart failure with preserved ejection fraction [HFpEF];left ventricular ejection fraction [LVEF] ≥50%) and 40 with a reduced ejection fraction (heart failure with reduced ejection fraction [HFrEF];LVEF < 50%). PH was diagnosed with RHC in 77.5% of patients. Patients with PH showed worse hemodynamic parameters and higher mortality. HFrEF-PH patients had worse survival than HFpEF-PH patients. CAD-HF patients with an enlarged left ventricular end-diastolic diameter and reduced hemoglobin were at higher risk of PH. Nitrate treatment reduced the risk of PH. Elevated creatinine and mean pulmonary arterial pressure (mPAP), diastolic pressure gradient (DPG) ≥7 mmHg, and previous myocardial infarction (MI) entailed a higher risk of mortality in CAD-HF patients with PH.Conclusions: PH is common in CAD-HF and worsens the hemodynamics and survival in these patients. Left ventricle enlargement and anemia increase the risk of PH in CAD-HF. Patients may benefit from nitrate medications. Renal impairment, elevated mPAP, DPG ≥7 mmHg, and previous MI are strong predictors of mortality in CAD-HF-PH patients.Trial Registration: ClinicalTrials.gov, NCT02164526. | Li Huang Lingpin Pang Qing Gu Tao Yang Wen Li Ruilin Quan Weiqing Su Weifeng Wu Fangming Tang Xiulong Zhu Jieyan Shen Jingzhi Sun Guangliang Shan Changming Xiong Shian Huang Jianguo He | 2022 | Chinese Medical Journal2022，，15： | 4 |
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