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| 1 | EFFECTS OF SPLITTER BLADES ON THE LAW OF INNER FLOW WITHIN CENTRIFUGAL PUMP IMPELLER显示文摘有 splitter 片的离心的泵 impeller 的内部流动地上的分析被数字模拟执行。把分析基于这,增加泵头和效率的原则被讨论。新结果从骚乱动能和相对速度分发的分析被获得:第一, splitter 片的无理的长度或偏差设计可以在 impeller 隧道引起大狂暴的变化,它在 impeller 插头流动的稳定性上有大效果;第二,流动分离的出现能被减少或从片装载的分析与 splitter 推迟了片,这被发现;第三,改革“喷气醒来”的结构上的 splitter 片的效果在不同流动剖面图从相对速度分发被解释,它在 impeller 显示出流动过程。内部流动分析验证表演测试结果和 PIV 测试的结果。 | YUAN Shouqi ZHANG Jinfeng YUAN Jianping HE Youshi FU Yuedeng | 2007 | Chinese Journal of Mechanical Engineering2007，20，5： | 16 |
| 2 | Comparative study of minimally invasive versus open esophagectomy for esophageal cancer in a single cancer center显示文摘 | Mu Juwei Yuan Zuyang Zhang Baihua Li Ning Lyu Fang Mao Yousheng Xue Qi Gao Shugeng Zhao Jun Wang Dali Li Zhishan Gao Yushun Zhang Liangze Huang Jinfeng Shao Kang Feng Feiyue Zhao Liang Li Jian Cheng Guiyu Sun Kelin He Jie | 2014 | Chinese Medical Journal2014，，4： | 13 |
| 3 | Early prediction of pathological outcomes to neoadjuvant chemotherapy in breast cancer patients using automated breast ultrasound显示文摘Objective: Early assessment of response to neoadjuvant chemotherapy(NAC) for breast cancer allows therapy to be individualized.The optimal assessment method has not been established.We investigated the accuracy of automated breast ultrasound(ABUS) to predict pathological outcomes after NAC.Methods: A total of 290 breast cancer patients were eligible for this study.Tumor response after 2 cycles of chemotherapy was assessed using the product change of two largest perpendicular diameters(PC) or the longest diameter change(LDC).PC and LDC were analyzed on the axial and the coronal planes respectively.Receiver operating characteristic(ROC) curves were used to evaluate overall performance of the prediction methods.Youden's indexes were calculated to select the optimal cut-off value for each method.Sensitivity, specificity,positive and negative predictive values(PPV and NPV) and the area under the ROC curve(AUC) were calculated accordingly.Results: yp T0/is was achieved in 42 patients(14.5%) while yp T0 was achieved in 30 patients(10.3%) after NAC.All four prediction methods(PC on axial planes, LDC on axial planes, PC on coronal planes and LDC on coronal planes) displayed high AUCs(all>0.82), with the highest of 0.89 [95% confidence interval(95% CI), 0.83–0.95]when mid-treatment ABUS was used to predict final pathological complete remission(p CR).High sensitivities(85.7%–88.1%) were observed across all four prediction methods while high specificities(81.5%–85.1%) were observed in two methods used PC.The optimal cut-off values defined by our data replicate the WHO and the RECIST criteria.Lower AUCs were observed when mid-treatment ABUS was used to predict poor pathological outcomes.Conclusions: ABUS is a useful tool in early evaluation of p CR after NAC while less reliable when predicting poor pathological outcomes. | Xinguang Wang Ling Huo Yingjian He Zhaoqing Fan Tianfeng Wang Yuntao Xie Jinfeng Li Tao Ouyang | 2016 | Chinese Journal of Cancer Research2016，28，5： | 11 |
| 4 | Biomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration显示文摘Issues caused by maxillofacial tumours involve not only dealing with tumours but also repairing jaw bone defects.In traditional tumour therapy,the systemic toxicity of chemotherapeutic drugs,invasive surgical resection,intractable tumour recurrence,and metastasis are major threats to the patients’lives in the clinic.Fortunately,biomaterial-based intervention can improve the efficiency of tumour treatment and decrease the possibility of recurrence and metastasis,suggesting new promising antitumour therapies.In addition,maxillofacial bone tissue defects caused by tumours and their treatment can negatively affect the physiological and psychological health of patients,and investment in treatment can result in a multitude of burdens to society.Biomaterials are promising options because they have good biocompatibility and bioactive properties for stimulation of bone regeneration.More interestingly,an integrated material regimen that combines tumour therapy with bone repair is a promising treatment option.Herein,we summarized traditional and biomaterial-mediated maxillofacial tumour treatments and analysed biomaterials for bone defect repair.Furthermore,we proposed a promising and superior design of dual-functional biomaterials for simultaneous tumour therapy and bone regeneration to provide a new strategy for managing maxillofacial tumours and improve the quality of life of patients in the future. | Bowen Tan Quan Tang Yongjin Zhong Yali Wei Linfeng He Yanting Wu Jiabao Wu Jinfeng Liao | 2021 | International Journal of Oral Science2021，13，1： | 9 |
| 5 | A review on ignition mechanisms and characteristics of magnesium alloys显示文摘Magnesium alloys have become more attractive because of their low density and electromagnetic shielding effectiveness in the aerospace industry.However,some unpredictable situation may lead to the ignition of magnesium alloys.In this review,the thermodynamic conditions and transfer processes of magnesium alloys ignition are analyzed from the point of mechanisms.The criteria of ignition are emphasized.In addition,ignitability and flammability test systems are compared.And a more suitable method to assess the potential ignition and flammability risks of magnesium alloys in extreme environments is recommended.Furthermore,the ignition characteristics of magnesium alloys are discussed in detail.It was found that the ignition of magnesium alloys is a complex process determined by internal properties such as thermo-physical properties,oxide film properties,chemical compositions and geometrical parameters,as well as the external environment such as gas species,oxygen concentration and oxygen pressure.Ignition temperature is not physical constants of materials.It is not simply assumed that ignition may occur when the temperature of Mg alloys reaches a certain ignition point.Finally,the unsolved issues in the ignition of magnesium alloys are pointed out and the future investigation are suggested for improving the safety and reliability of magnesium alloys in the aerospace applications. | Dong Han Jin Zhang Jinfeng Huang Yong Lian Guangyu He | 2020 | Journal of Magnesium and Alloys2020，8，2： | 7 |
| 6 | Source apportionment of PM_(2.5)light extinction in an urban atmosphere in China显示文摘Haze in China is primarily caused by high pollution of atmospheric fine particulates(PM2.5).However, the detailed source structures of PM2.5 light extinction have not been well established, especially for the roles of various organic aerosols, which makes haze management lack specified targets. This study obtained the mass concentrations of the chemical compositions and the light extinction coefficients of fine particles in the winter in Dongguan, Guangdong Province, using high time resolution aerosol observation instruments. We combined the positive matrix factor(PMF) analysis model of organic aerosols and the multiple linear regression method to establish a quantitative relationship model between the main chemical components, in particular the different sources of organic aerosols and the extinction coefficients of fine particles with a high goodness of fit(R^2= 0.953). The results show that the contribution rates of ammonium sulphate,ammonium nitrate, biomass burning organic aerosol(BBOA), secondary organic aerosol(SOA) and black carbon(BC) were 48.1%, 20.7%, 15.0%, 10.6%, and 5.6%, respectively. It can be seen that the contribution of the secondary aerosols is much higher than that of the primary aerosols(79.4% versus 20.6%) and are a major factor in the visibility decline. BBOA is found to have a high visibility destroying potential, with a high mass extinction coefficient, and was the largest contributor during some high pollution periods. A more detailed analysis indicates that the contribution of the enhanced absorption caused by BC mixing state was approximately 37.7% of the total particle absorption and should not be neglected. | Zijuan Lan Bin Zhang Xiaofeng Huang Qiao Zhu Jinfeng Yuan Liwu Zeng Min Hu Lingyan He | 2018 | Journal of Environmental Sciences2018，30，1： | 7 |
| 7 | Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging显示文摘Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy(DN)is vital for more accurate understanding the molecular pathological signature and developing novel therapeutic strategies.In the present study,a spatial-resolved metabolomics approach based on air flowassisted desorption electrospray ionization(AFADESI)and matrix-assisted laser desorption ionization(MALDI)integrated mass spectrometry imaging(MSI)was proposed to investigate tissue-specific metabolic alterations in the kidneys of high-fat diet-fed and streptozotocin(STZ)-treated DN rats and the therapeutic effect of astragalosideⅣ,a potential anti-diabetic drug,against DN.As a result,a wide range of functional metabolites including sugars,amino acids,nucleotides and their derivatives,fatty acids,phospholipids,sphingolipids,glycerides,carnitine and its derivatives,vitamins,peptides,and metal ions associated with DN were identified and their unique distribution patterns in the rat kidney were visualized with high chemical specificity and high spatial resolution.These region-specific metabolic disturbances were ameliorated by repeated oral administration of astragaloside Ⅳ(100 mg/kg)for 12 weeks.This study provided more comprehensive and detailed information about the tissue-specific metabolic reprogramming and molecular pathological signature in the kidney of diabetic rats.These findings highlighted the promising potential of AFADESI and MALDI integrated MSI based metabolomics approach for application in metabolic kidney diseases. | Zhonghua Wang Wenqing Fu Meiling Huo Bingshu He Yaqi Liu Lu Tian Wanfang Li Zhi Zhou Baili Wang Jianzhen Xia Yanhua Chen Jinfeng Wei Zeper Abliz | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 7 |
| 8 | Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS:Rg1 excretion in rat bile, urine and feces显示文摘Ginsenoside Rg1(Rg1), the major effective component of ginseng, has been shown to have multiple bioactivities, but low oral bioavailability. The aim of this study was to develop a simple, sensitive and rapid high performance liquid chromatography–tandem mass spectrometry(LC–MS/MS) method, which could be used to validate and quantify the concentrations of Rg1 and its metabolites in Sprague-Dawley rat bile,urine, and feces after oral administration(25 mg/kg). Calibration curves offered satisfactory linearity(r40.995)within the determined ranges. Both intra-day and inter-day variances were less than 15%, and the accuracy was within 80–120%. The excretion recoveries of Rg1, ginsenoside Rh1(Rh1), and protopanaxatriol(Ppt) in bile,urine, and feces combined were all greater than 70%. The fecal excretion recoveries of Rg1, Rh1, and Ppt were40.11%, 22.19%, and 22.88%, respectively, whereas 6.88% of Rg1 and 0.09% of Rh1 were excreted in bile.Urinary excretion accounted for only 0.04% of Rg1. In conclusion, the observed excretion profiles for Rg1 and its metabolites after oral administration are helpful for understanding the poor oral bioavailability of Rg1 and will aid further investigations of Rg1 as a pharmacologically active component. | Chiyu He Ru Feng Yupeng Sun Shifeng Chu Ji Chen Chao Ma Jie Fu Zhenxiong Zhao Min Huang Jiawen Shou Xiaoyang Li Yuzhu Wang Jinfeng Hu Yan Wang Juntian Zhang | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 6 |
| 9 | The novel H1N1 Influenza A global airline transmission and early warning without travel containments显示文摘A novel influenza A (H1N1) has been spreading worldwide. Early studies implied that international air travels might be key cause of a severe potential pandemic without appropriate containments. In this study, early outbreaks in Mexico and some cities of United States were used to estimate the preliminary epidemic parameters by applying adjusted SEIR epidemiological model, indicating transmissibility infectivity of the virus. According to the findings, a new spatial allocation model totally based on the real-time airline data was established to assess the potential spreading of H1N1 from Mexico to the world. Our estimates find the basic reproductive number R0 of H1N1 is around 3.4, and the effective reproductive number fall sharply by effective containment strategies. The finding also implies Spain, Canada, France, Panama, Peru are the most possible country to be involved in severe endemic H1N1 spreading. | CHANG ChaoYi CAO ChunXiang WANG Qiao CHEN Yu CAO ZhiDong ZHANG Hao DONG Lei ZHAO Jian XU Min GAO MengXu ZHONG ShaoBo HE QiSheng WANG JinFeng LI XiaoWen | 2010 | Chinese Science Bulletin2010，55，26： | 6 |
| 10 | Performances of improved Tent chaos-based FM radar signal显示文摘A novel algorithm is proposed to solve the poor performance problem of the Tent chaos-based frequency modulation(FM) signal for range-Doppler imaging,which takes it into complex multi-segment system by increasing its segments.The simulation results show that the effectiveness of the proposed algorithm,as well as the performance of the improved Tent FM signal is obvious in a multipath or noise propagation environment. | Shaobin Xie Zishu He Jinfeng Hu Lidong Liu Jichun Pan | 2012 | Journal of Systems Engineering and Electronics2012，23，3： | 6 |
| 11 | Topological r-entropy and measure-theoretic r-entropy of a continuous map显示文摘In this paper,we introduce the concept of measure-theoretic r-entropy of a continuous map on a compact metric space,and get the results as follows:1.Measure-theoretic entropy is the limit of measure-theoretic r-entropy and topological entropy is the limit of topological r-entropy(r → 0);2.Topological r-entropy is more than or equal to the supremum of 4r-entropy in the sense of Feldman's definition,where the measure varies among all the ergodic Borel probability measures. | REN YunLi HE LianFai LV JinFeng ZHENG GuoPing | 2011 | Science China Mathematics2011，54，6： | 5 |
| 12 | Atomically Smooth Ultrathin Films of Topological Insulator Sb_(2)Te_(3)显示文摘The growth and characterization of single-crystalline thin films of topological insulators(TIs)is an important step towards their possible applications.Using in situ scanning tunneling microscopy(STM)and angle-resolved photoemission spectroscopy(ARPES),we show that moderately thick Sb_(2)Te_(3)films grown layer-by-layer by molecular beam epitaxy(MBE)on Si(111)are atomically smooth,single-crystalline,and intrinsically insulating.Furthermore,these films were found to exhibit a robust TI electronic structure with their Fermi energy lying within the energy gap of the bulk that intersects only the Dirac cone of the surface states.Depositing Cs in situ moves the Fermi energy of the Sb_(2)Te_(3)films without changing the electronic band structure,as predicted by theory.We found that the TI behavior is preserved in Sb_(2)Te_(3)films down to five quintuple layers(QLs). | Guang Wang Xiegang Zhu Jing Wen Xi Chen Ke He Lili Wang Xucun Ma Ying Liu Xi Dai Zhong Fang Jinfeng Jia Qikun Xue | 2010 | Nano Research2010，3，12： | 5 |
| 13 | Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes显示文摘As an excitatory transmitter system,the glutamatergic transmitter system controls excitability and conductivity of neurons.Since both cardiomyocytes and neurons are excitable cells,we hypothesized that cardiomyocytes may also be regulated by a similar system. | Duanyang Xie Ke Xiong Xuling Su Guanghua Wang Qiang Ji Qicheng Zou Lingling Wang Yi Liu Dandan Liang Jinfeng Xue Luxin Wang Xueting Gao Xingdong Gu Hongyu Liu r Xiaoyu He Li Li Jian Yang Youming Lu Luying Peng Yi-Han Chen | 2021 | Cell Research2021，31，9： | 5 |
| 14 | CFD-DEM simulation of fluid-solid flow of a tapered column separation bed显示文摘Research on recycling waste Printed Circuit Boards(PCB) is at the forefront of preventing environmental pollution and finding ways to recycle resources.The Tapered Column Separation Bed(TCSB) is invented aiming at disposing the problem that fine particles of waste printed circuit boards cannot be separated efficiently so as to obtain further insight about the underlying mechanisms and demonstrate the separation feasibility in the tapered column separation bed.In this work,a Computational Fluid Dynamics(CFD) coupled with Discrete Element Method(DEM) model for two-phase flow has been extended to simulate the fluid-solid flow in the tapered column separation bed.Its validity is demonstrated by its successful capturing the key features of particles' flow pattern,velocity,the pressure distribution,the axial position with time and axial force for particles with different densities.Simulation results show that the plastic particles and resin particles become overflow,while copper particles,iron particles and aluminum particles successively become underflow,with a discharge water flow rate of 1 m^3/h,an obliquity of 30°.The simulated results agree reasonably well with the experimental observation.Using this equipment to separate waste PCBs is feasible,theoretically. | Duan Chenlong Sheng Cheng Wu Lingling Zhao Yuemin He Jinfeng | 2015 | International Journal of Mining Science and Technology2015，25，5： | 4 |
| 15 | A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy显示文摘The combination of Ce6,an acknowledged photosensitizer,and TPL,a natural anticancer agent,has been demonstrated as a useful strategy to reinforce the tumor growth suppression,as well as decrease the systemic side effects compared with their monotherapy.However,in view of the optimal chemo-photodynamic combination efficiency,there is still short of the feasible nanovehicle to steadily co-deliver Ce6 and TPL,and stimuli-responsively burst release drugs in tumor site.Herein,we described the synergistic antitumor performance of a pH-sensitive supramolecular nanosystem,mediated by the host–guest complexing betweenβ-CD and acid pH-responsive amphiphilic co-polymer mPEG-PBAE-mPEG,showing the shell–core structural micelles with the tightβ-CD layer coating.Both Ce6 and TPLwere facilely co-loaded into the spherical supramolecular NPs(TPL+Ce6/NPs)by one-step nanoprecipitation method,with an ideal particle size(156.0 nm),acid pH-responsive drug release profile,and enhanced cellular internalization capacity.In view of the combination benefit of photodynamic therapy and chemotherapy,as well as co-encapsulation in the fabricated pH-sensitive supramolecular NPs,TPL+Ce6/NPs exhibited significant efficacy to suppress cellular proliferation,boost ROS level,lower MMP,and promote cellular apoptosis in vitro.Particularly,fluorescence imaging revealed that TPL+Ce6/NPs preferentially accumulated in the tumor tissue area,with higher intensity than that of free Ce6.As expected,upon 650-nm laser irradiation,TPL+Ce6/NPs exhibited a cascade of amplified synergistic chemo-photodynamic therapeutic benefits to suppress tumor progression in both hepatoma H22 tumor-bearingmice and B16 tumor-bearingmice.More importantly,lower systemic toxicitywas found in the tumor-bearingmice treated with TPL+Ce6/NPs.Overall,the designed supramolecular TPL+Ce6/NPs provided a promising alternative approach for chemo-photodynamic therapy in tumor treatment. | Yihan Wu Jingjing Li Xuemei Zhong Jinfeng Shi Yanfen Cheng Chenglin He Jiaxin Li Liang Zou Chaomei Fu Meiwan Chen Jinming Zhang Huile Gao | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，2： | 4 |
| 16 | Timing and structural controls on skarn-type and vein-type mineralization at the Xitian tin-polymetallic deposit, Hunan Province, SE China显示文摘Xitian tin-polymetallic deposit, located in the eastern Hunan Province, SE China, hosts quartz vein and skarn in the contact zone between carbonate and two stages granites. Critical geodynamic questions for South China are whether different types of mineralization form in the same time and how the magmatism–tectonic system controls the ore-forming process. Based on the distribution of the orebodies, six cassiterite samples from different types of mineralization are collected for dating. In-situ LA-MCICP-MS U–Pb isotopic data yielded concordia low intercept ages between 154 and 157 Ma, indicating that different types of mineralization belong to the same magmatism–mineralization system. Coupled with the study of the kinematic indicators, it suggests that the structural control of the wall rocks constrain the types of mineralization. These results provide further evidence of a close temporal link between the structure and the tin-polymetallic mineralization in Xitian deposit. Considering the structure in the district, granite dome plays an important role in the ore-forming process. The age and structural signatures in Xitian deposit are the response to the subduction of Pacific Plate. | Miao He Quanlin Hou Qing Liu Jiheng Zhang Jinfeng Sun Shichong Wu Haofeng Zhu | 2018 | Acta Geochimica2018，37，2： | 4 |
| 17 | Splitting positive definite mixed element method for viscoelasticity wave equation显示文摘切开积极明确的混合有限元素方法的 A 为秒顺序粘弹性波浪方程被建议。建议过程能被分成三个独立对称的积极明确的 integro 微分的分系统并且不需要解决方程的 a coupled 系统。错误估计为 semidiscrete 和充分分离的计划被导出。为 semidiscrete 计划的存在和唯一被证明。最后,一个数字例子被提供说明方法的效率。 | Yang LIU Hong LI Wei GAO Siriguleng HE Jinfeng WANG | 2012 | Frontiers of Mathematics in China2012，7，4： | 3 |
| 18 | Synergistic effects of lanthanum oxide on a novel intumescent flame retardant polypropylene system显示文摘 | Yantao Li Bin Li Jinfeng Dai He Jia Suliang Gao | 2007 | Polymer Degradation and Stability2007，，1： | 2 |
| 19 | Increased survival in hepatocellular carcinoma with iodine-125 implantation plus radiofrequency ablation: A prospective randomized controlled trial显示文摘 | Kaiyun Chen Guihua Chen Hanning Wang Hua Li Jinfeng Xiao Xiaopeng Duan Jiwen He Ke He Guoan Xiang | 2014 | Journal of Hepatology2014，，： | 2 |
| 20 | Cloning and characterization of a novel CBL-interacting protein kinase from maize显示文摘 | Jinfeng Zhao Zhenfei Sun Jun Zheng Xiying Guo Zhigang Dong Junling Huai Mingyue Gou Junguang He Yongsheng Jin Jianhua Wang Guoying Wang | 2009 | Plant Molecular Biology2009，，6： | 2 |
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