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| 1 | Distribution of organic carbon fractions in soil aggregates in Chinese fir plantations with different stand ages显示文摘Background:Revealing the variations in soil aggregate-related organic carbon(OC)and labile organic carbon(LOC)fractions in a chronosequence of Chinese fir plantations plays an important role in better understanding the impact of soil carbon sink or source on the Chinese fir plantation ecosystem.In this study,soil samples in a depth of 0–20 cm were collected from Chinese fir plantations at different stand ages(0,9,17,and 26 years old)in Guangxi,China.With the optimal moisture sieving method adopted,the soil aggregates of 4 different sizes were obtained,including>2-mm,2–1-mm,1–0.25-mm,and<0.25-mm aggregates.Soil OC and LOC fractions were measured in the aggregates of different sizes.The LOC fractions included readily oxidizable carbon(ROC),particulate organic carbon(POC),microbial biomass carbon(MBC),water-soluble organic carbon(WOC),and mineralized organic carbon(MOC).Results:Soil aggregate stability,as indicated by the mean weight diameter(MWD),was the highest in the 17-yearold Chinese fir plantations and was significantly positively related(p<0.05)to the concentrations of OC and LOC fractions(except for the ROC and MOC),with the POC in particular.As for all stand ages of Chinese fir plantations,the concentrations of soil OC and LOC fractions were significantly increased as the aggregate size decreased.Consequently,there were more OC and LOC fractions distributed in the<0.25-mm aggregates.During the stand development,the concentrations of soil OC and LOC fractions first increased and then decreased,with the highest levels detected in the 17-year-old Chinese fir plantations,indicating that the 17-year-old Chinese fir plantations were conducive to the accumulation of soil OC and LOC fractions.Conclusion:After 17 years of planting,promoted soil carbon(especially for the POC)accumulation contributes significantly to enhancing soil aggregate stability for the Chinese fir plantations in Guangxi,China. | Xinxin He Yongzhen Huang Qianchun Zhang Shaoming Ye Shengqiang Wang | 2021 | Ecological Processes2021，10，1： | 11 |
| 2 | Identification and characterization of rice blast resistance gene Pid4 by a combination of transcriptomic profiling and genome analysis显示文摘Map-based cloning of plant disease resistance (R) genes is time-consuming. Here, we reported the isolation of blast R gene Pid4 using comparative transcriptomic profiling and genome-wide sequence analysis. Pid4 encodes a coiled-coil nucleotide-binding site leucine-rich repeat(CC-NBS-LRR) protein and is constitutively expressed at diverse developmental stages in the rice variety Digu. The Pid4 protein is localized in both the nucleus and cytoplasm. Introduction of Pid4 into susceptible rice cultivars confers race-specific resistance to leaf and neck blast. Amino acid sequence comparison and blast resistance spectrum tests showed that Pid4 is a novel R gene, different from the previously reported R genes located in the same gene cluster. A Pid4 Indel marker was developed to facilitate the identification of Pid4 in different rice varieties. We demonstrated that a plant R gene can be quickly isolated using transcriptomic profiling coupled with genome-wide sequence analysis. | Zhixiong Chen Wen Zhao Xiaobo Zhu Chengdong Zou Junjie Yin Mawsheng Chern Xiaogang Zhou Heng Ying Xin Jiang Yongzhen Li Haicheng Liao Mengping Cheng Weitao Li Min He Jing Wang Jichun Wang Bingtian Ma Jirui Wang Shigui Li Lihuang Zhu Xuewei Chen | 2018 | Journal of Genetics and Genomics2018，45，12： | 7 |
| 3 | Overview and countermeasures of cancer burden in China显示文摘Cancer is one of the leading causes of human death worldwide.Treatment of cancer exhausts significant medical resources,and the morbidity and mortality caused by cancer is a huge social burden.Cancer has therefore become a serious economic and social problem shared globally.As an increasingly prevalent disease in China,cancer is a huge challenge for the country’s healthcare system.Based on recent data published in the Journal of the National Cancer Center on cancer incidence and mortality in China in 2016,we analyzed the current trends in cancer incidence and changes in cancer mortality and survival rate in China.And also,we examined several key risk factors for cancer pathogenesis and discussed potential countermeasures for cancer prevention and treatment in China. | Yian Wang Qijia Yan Chunmei Fan Yongzhen Mo Yumin Wang Xiayu Li Qianjin Liao Can Guo Guiyuan Li Zhaoyang Zeng Wei Xiong He Huang | 2023 | Science China(Life Sciences)2023，66，11： | 5 |
| 4 | Circular RNA circCCNB1 inhibits the migration and invasion of nasopharyngeal carcinoma through binding and stabilizing TJP1 mRNA显示文摘Nasopharyngeal carcinoma(NPC)is a malignant tumor that usually occurs in people from Southeast Asia and Southern China.NPC is prone to migration and invasion,leading to poor prognosis.A large number of circular RNAs(circ RNAs)exacerbate the process of metastasis in NPC;however,their underlying mechanisms remain unclear.We found that the circular RNA circ CCNB1,encoded by the oncogene CCNB1,was downregulated in NPC biopsies and cell lines.In vitro assays show that circ CCNB1 inhibits NPC cell migration and invasion.Moreover,circ CCNB1 induces a protein,nuclear factor 90(NF90),to bind and prolong the half-life of tight junction protein 1(TJP1)m RNA.Upregulation of TJP1 enhances tight junctions between cancer cells and inhibits NPC cell migration and invasion.This study reveals a novel biological function of circ CCNB1 in the migration and invasion of NPC by enhancing the tight junctions of cancer cells by binding to NF90 proteins and TJP1 m RNA,and may provide a potential therapeutic target for NPC. | Mengyao Zhao Yian Wang Fenghua Tan Lingyun Liu Xiangchan Hou Chunmei Fan Le Tang Yongzhen Mo Yumin Wang Qijia Yan Zhaojian Gong Zheng Li Qianjin Liao Can Guo He Huang Xi Zeng Guiyuan Li Zhaoyang Zeng Wei Xiong Fuyan Wang | 2022 | Science China(Life Sciences)2022，65，11： | 4 |
| 5 | High hydrogen yield from a two-step process of dark- and photo-fermentation of sucrose显示文摘 | Yongzhen Tao Yang Chen Yongqiang Wu Yanling He Zhihua Zhou | 2006 | International Journal of Hydrogen Energy2006，，2： | 2 |
| 6 | Advanced nitrogen removal with simultaneous Anammox and denitrification in sequencing batch reactor显示文摘 | Rui Du Yongzhen Peng Shenbin Cao Chengcheng Wu Dongchen Weng Shuying Wang Jianzhong He | 2014 | Bioresource Technology2014，，： | 2 |
| 7 | An atlas of CNV maps in cattle, goat and sheep显示文摘Copy number variation(CNV)is the most prevalent type of genetic structural variation that has been recognized as an important source of phenotypic variation in humans,animals and plants.However,the mechanisms underlying the evolution of CNVs and their function in natural or artificial selection remain unknown.Here,we generated CNV region(CNVR)datasets which were diverged or shared among cattle,goat,and sheep,including 886 individuals from 171 diverse populations.Using 9 environmental factors for genome-wide association study(GWAS),we identified a series of candidate CNVRs,including genes relating to immunity,tick resistance,multi-drug resistance,and muscle development.The number of CNVRs shared between species is significantly higher than expected(P<0.00001),and these CNVRs may be more persist than the single nucleotide polymorphisms(SNPs)shared between species.We also identified genomic regions under long-term balancing selection and uncovered the potential diversity of the selected CNVRs close to the important functional genes.This study provides the evidence that balancing selection might be more common in mammals than previously considered,and might play an important role in the daily activities of these ruminant species. | Yongzhen Huang Yunjia Li Xihong Wang Jiantao Yu Yudong Cai Zhuqing Zheng Ran Li Shunjin Zhang Ningbo Chen Hojjat Asadollahpour Nanaei Quratulain Hanif Qiuming Chen Weiwei Fu Chao Li Xiukai Cao Guangxian Zhou Shudong Liu Sangang He Wenrong Li Yulin Chen Hong Chen Chuzhao Lei Mingjun Liu Yu Jiang | 2021 | Science China(Life Sciences)2021，64，10： | 2 |
| 8 | Advanced nitrogen removal with simultaneous Anammox and denitrification in sequencing batch reactor显示文摘 | Rui Du Yongzhen Peng Shenbin Cao Chengcheng Wu Dongchen Weng Shuying Wang Jianzhong He | 2014 | Bioresource Technology2014，，： | 1 |
| 9 | Characteristics of a new photosynthetic bacterial strain for hydrogen production and its application in wastewater treatment 显示文摘 | Yongzhen Tao Yanling He Yongqiang Wu | 2008 | International Journal of Hydrogen Energy2008，33，3： | 1 |
| 10 | Detailed model and investigation of gain saturation and carrier spatial hole burning for a semiconductor optical amplifier with gain clamping by a vertical laser field显示文摘 | JIANG Chaoyuan HE Yongzhen YANG LiJuan | 2004 | IEEE Journal of Quantum Electronics2004，40，5： | 1 |
| 11 | Characteristics of a new photosynthetic bacterial strain for hydrogen production and its application in wastewater treatment 显示文摘 | TAO Yongzhen HE Yanling WU Yongqiang | 2008 | Hydrogen Energy2008，33，3： | 1 |
| 12 | Characteristics of a new photosynthetic bacterial strain for hydrogen production and its application in wastewater treatment 显示文摘 | Tao Yongzhen He Yarding Wu Yongqiang | 2008 | International Journal of Hydrogen Energy2008，330，： | 1 |
| 13 | Characteristics of a new photosynthetic bacterial strain for hydrogen production and its application in wastewater treatment显示文摘 | Yongzhen Tao Yanling He Yongqiang Wu Fanghua Liu Xinfeng Li Wenming Zong Zhihua Zhou | 2008 | International Journal of Hydrogen Energy2008，，3： | 1 |
| 14 | Selective coordination of polyazin sapanisertib with halide vacancy for printable mesoscopicperovskite solar cells显示文摘The mitigation of under-coordinated Pb^(2+)(halide vacancy)defect remains an imperative challenge in the perovskite solar cells,especially printable mesoscopic perovskite solar cells(FP-PsCs).Here we re port a commercial-available polyazin anticancer drug Sapanisertib as coordination passivator of halide vacancies in FP-PSCs,thereby achieving the photoelectric conversion efficiency(PCE)to 18.46%,along with a record certified PCE of 18.27%.In polazin Sapanisertib(Sap),there exists two kinds of nitrogen atoms:in-aromatic ring(in purine and oxazole rings,IAR-Ns)and out-aromatic ring(substituted amino groups,OAR-Ns).Through multiple characterizations,and DFT calculations show that substituted amino groups OAR-Ns hardly get interaction with the halide vacancy due to the distribution of charge density in Sapanisertib.Our work suggests that the selective coordination is of great significance for the design of high-performance passivators for printable mesoscopic perovskite solar cells. | Dun Ma Xiujun He Jingshan He Huanxin Guo Yongzhen Wu Wenjun Wu Weihong Zhu | 2023 | Chinese Chemical Letters2023，34，12： | 0 |
| 15 | Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates显示文摘The orphan nuclear receptor Nur77 is a critical regulator of the survival and death of tumor cells.The pro-death effect of Nur77 can be regulated by its interaction with Bcl-2,resulting in conversion of Bcl-2 from a survival to killer.As Bcl-2 is overexpressed in various cancers preventing them from apoptosis and promoting their resistance to chemotherapy,targeting the apoptotic pathway of Nur77/Bcl-2 may lead to new cancer therapeutics.Here,we report our identification of XS561 as a novel Nur77 ligand that induces apoptosis of tumor cells by activating the Nur77/Bcl-2 pathway.In vitro and animal studies revealed an apoptotic effect of XS561 in a range of tumor cell lines including MDA-MB-231 triple-negative breast cancer(TNBC)and MCF-7/LCC2 tamoxifen-resistant breast cancer(TAMR)in a Nur77-dependent manner.Mechanistic studies showed XS561 potently induced the translocation of Nur77 from the nucleus to mitochondria,resulting in mitochondria-related apoptosis.Interestingly,XS561-induced accumulation of Nur77 at mitochondria was associated with XS561 induction of Nur77 phase separation and the formation of Nur77/Bcl-2 condensates.Together,our studies identify XS561 as a new activator of the Nur77/Bcl-2 apoptotic pathway and reveal a role of phase separation in mediating the apoptotic effect of Nur77 at mitochondria. | Xiaohui Chen Meichun Gao Yongzhen Xia Xin Wang Jingbo Qin Hongying He Weirong Liu Xiaowei Zhang Shuangzhou Peng Zhiping Zeng Ying Su Xiaokun Zhang | 2024 | Acta Pharmaceutica Sinica B2024，14，3： | 0 |
| 16 | New dual functional CYP450 gene involves in isoflavone biosynthesis in Glycine max L.显示文摘Glycine max L.accumulates a large amount of isoflavonoid compounds,which is beneficial for plant defense,plant-microbe symbiotic interactions,and human health.Several CYP450 subfamily genes are involved in the flavonoid biosynthetic pathway in plants.In the present study,we found 24 CYP82 subfamily genes were differentially expressed in various tissues of soybean,in Phytophthora sojae-infected soybean varieties and in soybean hairy roots treated with cell wall glucan elicitor.Six of them(GmCYP82A2,GmCYP82A3,GmCYP82A4,GmCYP82A23,GmCYP82C20 and GmCYP82D26)were co-expressed with other known isoflavonoid pathway genes in soybean.Their enzymatic activity in yeast feeding assays showed that only GmCYP82D26 was able to convert naringenin to daidzein with both aryl migration and dehydration function.When GmCYP82D26 was over-expressed in soybean hairy roots,the contents of the two major isoflavonoid aglycones in soybean(daidzein and genistein)were reduced,but total flavonoids were not affected.When GmCYP82D26 was suppressed by RNAi in the hairy roots,daidzein content was decreased but genistein content was increased,with unchanged total flavonoid content.GmCYP82D26 was found to be localized in the endoplasmic reticulum at subcellular level when transiently expressed in tobacco leaf epidermis.GmCYP82D26 gene was preferentially expressed in roots,with low expression level in other tissues in soybean.Homology modeling and molecular docking showed that GmCYP82D26 could form hydrogen bond with both HEM and naringenin at C5-OH and C4 carbonyl.All these results indicated that GmCYP82D26 possesses new and dual enzymatic activity,which bridges the two branches(daidzein and genistein branch)of isoflavonoid pathway in soybean. | Yaying Xia Chunfeng He Su Yan Jinyue Liu Haijun Huang Xue Li Qian Su Wenbo Jiang Yongzhen Pang | 2023 | Synthetic and Systems Biotechnology2023，8，1： | 0 |
| 17 | Research on cutting characteristics of fiber bundle with high-speed photography显示文摘Cutting is an essential and complicated process in many fields.Efficient and low-consumption cutting operations are of great significance for environmental protection and energy conservation.The development of high performance cutting parts relies on a deep understanding of the cutting process and cutting mechanism.In this research,a new type of cutting test bench with high-speed photography was developed,and the cutting tests were conducted on the jute fiber bundle from quasi-static cutting at 10 mm/s to dynamic cutting in the speed range of 0.6-2.4 m/s.The cutting process was captured by a high-speed camera.Analysis shows that compression exists before quasi-static cutting,and the compression force curve with respect to the compression ratio follows an exponential function.The cutting speed has a significant effect on cutting energy.The cutting energy consumption is not a monotonous function of cutting speed owing to the combined effect of elastic deformation and friction of fibers.The cutting energy increases with increasing cutting speed in the range of 0.6-1.2 m/s due to the increase of the friction within fibers and the friction between the blade and fibers.The cutting energy decreases with increasing cutting speed in the range of 1.2-1.8 m/s,and tends to be a fixed value when the cutting speed exceeds 1.8 m/s due to the stabilized elastic deformation and friction coefficient.From the perspective of energy saving,it is meaningless to increase the blade speed excessively when cutting fiber bundles. | Zhitao He Huiling Ding Sanming Du Zhen Li Jiangtao Ji Jian Li Yongzhen Zhang | 2020 | International Journal of Agricultural and Biological Engineering2020，13，3： | 0 |
| 18 | Neglected acidity pitfall:boric acid-anchoring hole-selective contact for perovskite solar cells显示文摘The spontaneous formation of self-assembly monolayer(SAM) on various substrates represents an effective strategy for interfacial engineering of optoele ctronic devices.Hole-selective SAM is becoming popular among high-performance inverted perovskite solar cells(PSCs),but the presence of strong acidic anchors(such as-PO_(3)H_(2)) in state-of-the-art SAM is detrimental to device stability.Herein,we report for the first time that acidity-weakened boric acid can function as an alternative anchor to construct efficient SAM-based hole-sele ctive contact(HSC) for PSCs.Theoretical calculations reve al that boric acid spontaneously chemisorbs onto indium tin oxide(ITO) surface with oxygen vacancies facilitating the adsorption progress.Spectroscopy and electrical measurements indicate that boric acid anchor significantly mitigates ITO corrosion.The excess boric acid containing molecules improves perovskite deposition and results in a coherent and well-passivated bottom interface,which boosts the fill factor(FF) performance for a variety of perovskite compositions.The optimal boric acid-anchoring HSC(MTPA-BA) can achieve power conversion efficiency close to 23% with a high FF of 85.2%.More importantly,the devices show improved stability:90% of their initial efficiency is retained after 2400 h of storage(ISOS-D-1) or 400 h of operation(ISOS-L-1),which are 5-fold higher than those of phosphonic acid SAM-based devices.Acidity-weakened boric acid SAMs,which are friendly to ITO,exhibits well the great potential to improve the stability of the interface as well as the device. | Huanxin Guo Cong Liu Honglong Hu Shuo Zhang Xiaoyu Ji Xiao-Ming Cao Zhijun Ning Wei-Hong Zhu He Tian Yongzhen Wu | 2023 | National Science Review2023，10，5： | 0 |
| 19 | Scale effect of circularly polarized luminescent signal of matter显示文摘Circularly polarized luminescence(CPL)is an important part in the research of modern luminescent materials and photoelectric devices.Usually,chiral molecules or chiral structures are the key factors to induce CPL spontaneous emission.In this study,a scale-effect model based on scalar theory was proposed to better understand the CPL signal of luminescent materials.Besides chiral structures being able to induce CPL,achiral ordered structures can also have a significant influence on CPL signals.These achiral structures are mainly reflected in the particle scale in micro-order or macro-order,i.e.the CPL signal measured under most conditions depends on the scale of the ordered medium,and does not reflect the inherent chirality of the excited state of the luminescent molecule.This kind of influence is difficult to be eliminated by simple and univers al strategies in macro-measurement.At the same time,it is found that the measurement entropy of CPL detection may be the key factor to determine the isotropy and anisotropy of the CPL signal.This discovery would bring new opportunities to the research of chiral luminescent materials.This strategy can also greatly reduce the development difficulty of CPL materials and show high application potential in biomedical,photoelectric information and other fields. | Siyu Sun Xiaolin Li Chen Xu Yan Li YongZhen Wu Ben L.Feringa He Tian Xiang Ma | 2023 | National Science Review2023，10，5： | 0 |
| 20 | Realization of solid-state red fluorescence and concentration-induced multicolor emission from N,B co-doped carbon dots显示文摘As a new type of luminescent material,carbon dots(CDs)have attracted increased attention for their superior optical properties in recent years.However,solidstate fluorescent CDs,especially with red emission,are still a major challenge.Here,CDs with solid-state red emission were synthesized by co-doping of N and B using the one-step microwave method.The CD powder exhibits excitation-independent solid-state red fluorescence without any dispersion matrices,with optimum solid-state fluorescence wavelength of 623 nm.The hydrogen bonding interaction in CDs is helpful for solid-state fluorescence of CDs.The IG/ID value of CDs reaches up to 3.49,suggesting their very high graphitization degree,which is responsible for their red emission.In addition,CDs show the concentration-induced multicolor emission,which is attributed to the decreased energy gap in the high concentrated CD solution.To exploit their concentration-dependent emission,CDs with changing ratio in matrices are applied as a color-converting layer on ultraviolet chip to fabricate multicolor light-emitting diodes with light coordinates of(0.33,0.38),(0.41,0.48),(0.49,0.44),and(0.67,0.33),which belong to green,yellow,orange,and red light,respectively. | Junli Wang Jingxia Zheng Pinyi He Qiang Li Yongzhen Yang Xuguang Liu Juanzhi Yan Yi Zhang | 2023 | Frontiers of Materials Science2023，17，2： | 0 |
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