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78篇 您的检索式:作者名="Haibin Sun"
    题名 作者 年代 出处 被引量
1aunalysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza显示文摘Haibin Xu Jingyuan Song Hongmei Luo Yujun Zhang Qiushi Li Yingjie Zhu Jiang Xu Ying Li Chi Song Bo Wang Wei Sun Guoan Shen Xin Zhang Jun Qian Aijia Ji Zhichao Xu Xiang Luo Liu He Chuyuan Li Chao Sun Haixia Yah Guanghong Cui Xiwen Li Xian 'en Li Jianhe Wei Juyan Liu Yitao Wang Alice Hayward David Nelson Zemin Ning Reuben J. Peters Xiaoquan Qi Shilin Chen 2016Molecular Plant2016,9,6:70
2Three-dimensional Evolutionary Models of the Qiongxi Structures,Southwestern Sichuan Basin,China:Evidence from Seismic Interpretation and Geomorphology显示文摘褶层结束是在有压缩性的差错相关的褶层的学习的特色。如此的结束能由于戳差错上的排水量的损失或 / 并且形成一个侧面或倾斜的斜面。因此,高质量的地震数据将明白地帮助定义哪个机制应该为给定的差错相关的褶层的结束负责。在四川盆的 Qiongxi 和 Qiongxinan 结构,中国是拥有在他们之间的北结束和结构的僵绳的自然差错繁殖褶层的例子。合拢 / 指责几何学和沿着罢工排水量变化被工业 3-D 抑制地震体积。我们解释北结束和结构的僵绳附近的褶层的 plunge 由于排水量的损失罢工。与北结束联系的差错几何学变化从一在 Qiongxinan 结构的冠扁平斜面在排水量最大的地方,到简单地 Qiongxi 结构的北尖端附近的一个斜面,没有形成一个侧面或倾斜的斜面。在这研究,我们也使用排水模式,在沿着一个差错的排水量与推进为 Qiongxinan 的侧面的繁殖建议一个模型的持续时间成正比的 Qiongxinan 结构和假设的冠保存的胚胎的结构和 Qiongxi 结构。明确地,我们建议结构首先在易碎的单位以内作为一个孤立的差错斜面开始了。与弄短增加,差错变得以更弱的页岩单位与更低的分队连接创造 hybridized 差错繁殖褶层。我们的模型为 Qiongxinan 和 Qiongxi 结构的侧面的繁殖历史建议可能的解释,并且也提供一条其他的途径给在迟了的新生代在西南的四川盆证实以前的 Pingluoba 结构的活动。JIA Qiupeng JIA Dong LUO Liang CHEN Zhuxin LI Yiquan DENG Fei SUN Shengsi LI Haibin 2009Acta Geologica Sinica(English Edition)2009,83,2:17
3Adaptive fault-tolerant controller design for airbreathing hypersonic vehicle with input saturation显示文摘The problem of fault-tolerant control is discussed for the longitudinal model of an airbreathing hypersonic vehicle(AHV) with actuator faults and external disturbances.Firstly,a fault-tolerant control strategy is presented for the longitudinal model of an AHV,which guarantees that velocity and altitude track their reference trajectories at an exponential convergence rate.However,this method needs to know the minimum value of the actuator efficiency factor and the upper bound of the external disturbances,which makes it not easy to implement.Then an improved adaptive fault-tolerant control scheme is proposed,where two adaptive laws are employed to estimate the upper bound of the external disturbances and the minimum value of the actuator efficiency factor,respectively.Secondly,the problem of designing a control scheme with control constraints is further considered,and a new adaptive fault-tolerant control strategy with input saturation is designed to guarantee that velocity and altitude track their reference trajectories.Finally,simulation results are given to show the effectiveness of the proposed methods.Haibin Sun Shihua Li Changyin Sun 2013Journal of Systems Engineering and Electronics2013,24,3:12
4Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane显示文摘A series of polylactic acid (PLA) based nanocomposite fibrous membranes,including neat PLA,PLA/hydroxyapatite (HA) and PLA/HA/graphene oxide (GO),were fabricated via electrospinning method.The morphology and composition were investigated by scanning electron microscopy (SEM),X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) respectively.The thermal stability was determined by thermogravimetric analysis (TGA).To estimate the cytocompatibility of asprepared PLA/HA/GO fibrous membrane,MC3T3-E1 cells were cultured,and the corresponding cell adhesion and differentiation capability were investigated by fluorescence microscopy,SEM and MTT test.The electrospun ternary PLA/HA/GO membrane exhibited three-dimensional fibrous structure with relatively rough surface morphology,which made itself ideal for cell attachment and proliferation in bone tissue regeneration.The fluorescence microscopy,SEM and MTT test confirmed that the PLA/HA/GO nanocomposite fibrous membrane created a proper environment for the seeding and proliferation of MC3T3-E1 cells.MA HaiBin SU WenXin TAI ZhiXin SUN DongFei YAN XingBin LIU Bin XUE QunJi 2012Chinese Science Bulletin2012,57,23:11
5Pendulum-like oscillation controller for micro aerial vehicle with ducted fan based on LQR and PSO显示文摘This paper describes a novel type of pendulum-like oscillation controller for micro air vehicle(MAV) hover and stare state in the presence of external disturbances,which is based on linear-quadratic regulator(LQR) and particle swarm optimization(PSO).A linear mathematical model of pendulum phenomenon based upon actual wind tunnel test data representing the hover mode is established,and a hybrid LQR and PSO approach is proposed to stabilize oscillation.PSO is applied to parameter optimization of the designed LQR controller.A series of comparative experiments are conducted,and the results have verified the feasibility,effectiveness and robustness of our proposed approach.DUAN HaiBin SUN ChangHao 2013Science China(Technological Sciences)2013,56,2:9
6Markov decision evolutionary game theoretic learning for cooperative sensing of unmanned aerial vehicles显示文摘As one of the major contributions of biology to competitive decision making,evolutionary game theory provides a useful tool for studying the evolution of cooperation.To achieve the optimal solution for unmanned aerial vehicles(UAVs) that are carrying out a sensing task,this paper presents a Markov decision evolutionary game(MDEG) based learning algorithm.Each individual in the algorithm follows a Markov decision strategy to maximize its payoff against the well known Tit-for-Tat strategy.Simulation results demonstrate that the MDEG theory based approach effectively improves the collective payoff of the team.The proposed algorithm can not only obtain the best action sequence but also a sub-optimal Markov policy that is independent of the game duration.Furthermore,the paper also studies the emergence of cooperation in the evolution of self-regarded UAVs.The results show that it is the adaptive ability of the MDEG based approach as well as the perfect balance between revenge and forgiveness of the Tit-for-Tat strategy that the emergence of cooperation should be attributed to.SUN ChangHao DUAN HaiBin 2015Science China(Technological Sciences)2015,58,8:9
7Composite control method for stabilizing spacecraft attitude in terms of Rodrigues parameters显示文摘In this paper, the attitude stabilization problem of a rigid spacecraft described by Rodrigues parameters is investigated via a composite control strategy, which combines a feedback control law designed by a finite time control technique with a feedforward compensator based on a linear disturbance observer (DOB) method. By choosing a suitable coordinate transformation, the spacecraft dynamics can be divided into three second-order subsystems. Each subsystem includes a certain part and an uncertain part. By using the finite time control technique, a continuous finite time controller is designed for the certain part. The uncertain part is considered to be a lumped disturbance, which is estimated by a DOB, and a corresponding feedforward design is then implemented to compensate the disturbance. Simulation results are employed to confirm the effectiveness of the proposed approach.Sun Haibin Li Shihua 2013Chinese Journal of Aeronautics2013,26,3:8
8Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer显示文摘Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target(m TOR), inhibition of which could result in autophagic cell death(ACD). Though novel combination chemotherapy of autophagy inducers with chemotherapeutic agents is extensively investigated, nanomedicine-based combination therapy for ACD remains in infancy. In attempt to actively trigger ACD for synergistic chemotherapy, here we incorporated autophagy inducer rapamycin(RAP) into 7 pep-modified PEG-DSPE polymer micelles(7 pep-M-RAP) to specifically target and efficiently priming ACD of MCF-7 human breast cancer cells with high expression of transferrin receptor(Tf R). Cytotoxic paclitaxel(PTX)-loaded micelle(7 pep-M-PTX) was regarded as chemotherapeutic drug model. We discovered that with superior intracellular uptake in vitro and more tumor accumulation of micelles in vivo, 7 pep-M-RAP exhibited excellent autophagy induction and synergistic antitumor efficacy with 7 pep-M-PTX. Mechanism study further revealed that 7 pep-M-RAP and 7 pep-MPTX used in combination provided enhanced efficacy through induction of both apoptosis-and mitochondria-associated autophagic cell death. Together, our findings suggested that the targeted excess autophagy may provide a rational strategy to improve therapeutic outcome of breast cancer, and simultaneous induction of ACD and apoptosis may be a promising anticancer modality.Dong Mei Binlong Chen Bing He Haibin Liu Zhiqiang Lin Jialiang Lin Xiaoyan Zhang Ning Sun Libo Zhao Xiaoling Wang Qiang Zhang 2019Acta Pharmaceutica Sinica B2019,9,5:8
9Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a global crisis,urgently necessitating the development of safe,efficacious,convenient-to-store,and low-cost vaccine options.A major challenge is that the receptor-binding domain(RBD)-only vaccine fails to trigger long-lasting protective immunity if used alone for vaccination.Shiyu Sun Yueqi Cai Tian-Zhang Song Yang Pu Lin Cheng Hairong Xu Jing Sun Chaoyang Meng Yifan Lin Haibin Huang Fang Zhao Silin Zhang Yu Gao Jian-Bao Han Xiao-Li Feng Dan-Dan Yu Yalan Zhu Pu Gao Haidong Tang Jincun Zhao Zheng Zhang Jiaming Yang Zhenxiang Hu Yang-Xin Fu Yong-Tang Zheng Hua Peng 2021Cell Research2021,31,9:7
10Molecular phylogeny of coronaviruses including human SARS-CoV显示文摘Phylogenetic tree of coronaviruses (CoVs) in-cluding the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K- string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus ge-nomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV.GAO Lei QI Ji WEI Haibin SUN Yigang HAO Bailin 2003Chinese Science Bulletin2003,48,12:7
11Enhanced Fracture Toughness of Pressureless-sintered SiC Ceramics by Addition of Graphene显示文摘To enhance the fracture toughness of pressureless-sintered Si C ceramic, graphene was introduced as an additive. The effects of graphene contents on the fracture toughness, bending strength, micro-hardness,phase compositions, and microstructure evolutions of the Si C ceramics were investigated in detail by scanning electron microscopy, energy dispersive X-ray spectroscopy, and metallographic microscopy. The fracture toughness, bending strength and micro-hardness increased initially, and then decreased with the graphene content increasing from 0 to 5.0 wt%. The highest fracture toughness of 5.65 MPa m1/2was obtained for sample with 1.0 wt% graphene sintered at 2130 °C for 1 h in Ar, which was about 22.6% higher than that of Si C sample without graphene. In addition, the highest bending strength and microhardness of 434.14 MPa and 29.21 GPa corresponded to the Si C samples with graphene content of 0.5wt% and 2.0 wt%, respectively.Qisong Li Yujun Zhang Hongyu Gong Haibin Sun Wenjie Li Li Ma Yanshuang Zhang 2016Journal of Materials Science & Technology2016,32,7:5
12Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress显示文摘C18 ceramide plays an important role in the occurrence and development of oral squamous cell carcinoma.However,the function of ceramide synthase 1,a key enzyme in C18 ceramide synthesis,in oral squamous cell carcinoma is still unclear.The aim of our study was to investigate the relationship between ceramide synthase 1 and oral cancer.In this study,we found that the expression of ceramide synthase 1 was downregulated in oral cancer tissues and cell lines.In a mouse oral squamous cell carcinoma model induced by 4-nitroquinolin-1-oxide,ceramide synthase 1 knockout was associated with the severity of oral malignant transformation.Immunohistochemical studies showed significant upregulation of PCNA,MMP2,MMP9,and BCL2 expression and downregulation of BAX expression in the pathological hyperplastic area.In addition,ceramide synthase 1 knockdown promoted cell proliferation,migration,and invasion in vitro.Overexpression of CERS1 obtained the opposite effect.Ceramide synthase 1 knockdown caused endoplasmic reticulum stress and induced the VEGFA upregulation.Activating transcription factor 4 is responsible for ceramide synthase 1 knockdown caused VEGFA transcriptional upregulation.In addition,mild endoplasmic reticulum stress caused by ceramide synthase 1 knockdown could induce cisplatin resistance.Taken together,our study suggests that ceramide synthase 1 is downregulated in oral cancer and promotes the aggressiveness of oral squamous cell carcinoma and chemotherapeutic drug resistance.Wen Chen Chenzhou Wu Yafei Chen Yuhao Guo Ling Qiu Zhe Liu Haibin Sun Siyu Chen Zijian An Zhuoyuan Zhang Yi Li Longjiang Li 2021International Journal of Oral Science2021,13,1:3
13GF-2 Satellite 1m/4m Camera Design and In-Orbit Commissioning显示文摘GF-2(Gaofen-2) is the second high resolution imaging satellite of China high resolution earth observation system(CHEOS) and it is the first civilian high resolution imager with Ground sample distance(GSD) under1 m in China. The two 1 m/4 m cameras represent a breakthrough in comparison with the previous GF-1 camera. Recent advances in small relative aperture optics system design, vibration reduction, and high accuracy thermal control make it possible for this camera work perfect with high resolution, lihgtweight and high image quality performance. The in-orbit commissioning demonstrates that the performance of the cameras meets all the design requirements. The components of 1 m/4 m camera, the novel techniques adopted and in-orbit commissioning results are illustrated.HUANG Wei SUN shunrong JIANG Haibin GAO Chao ZONG Xiaoying 2018Chinese Journal of Electronics2018,27,6:3
14Quantitative climatic reconstruction of the Last Glacial Maximum in China显示文摘Quantitative paleoclimatic reconstruction is crucial for understanding the operation and evolution of the global climate system.For example,a quantitative paleoclimatic reconstruction for the Last Glacial Maximum(18±2 ka14C,LGM)is fundamental to understanding the evolution of Earth’s climate during the last glacial-interglacial cycle.Previous quantitative palaeoclimate reconstructions in China are generally based on statistical comparison of modern pollen assemblages and modern climate data.These methods are based on the premise that vegetation-climate interactions remain the same through time,and implicitly assume that the interactions are independent of changes in seasonality and atmospheric CO2concentration.However,these assumptions may not always be valid,which may affect the reconstructions.Here,we present the results of a quantitative study of the LGM climate of China based on an improved inverse vegetation model which incorporates physiological processes combined with a new China Quaternary Pollen Database.The results indicate that during the LGM,mean annual temperature(ANNT),mean temperature of the coldest month(MTCO)and mean temperature of the warmest month in China were lower by^5.6±0.8,~11.0±1.6 and^2.6±0.9°C,respectively,compared to today,and that the changes in ANNT were mainly due to the decrease of MTCO.The ANNT decrease in southern China was^5.5±0.5°C.Mean annual precipitation was lower by^46.3±17.8 mm compared to today and was especially low in northern China(~51.2±21.4 mm)due to the decrease in summer rainfall.Comparison of our results with recent outputs from paleoclimatic modelling reveals that while the latter are broadly consistent with our estimated changes in mean annual climatic parameters,there are substantial differences in the seasonal climatic parameters.Our results highlight the crucial importance of developing seasonal simulation on paleoclimatic models,as well as the need to improve the quality of paleoclimatic reconstructions based on proxy records from geological archives.Haibin WU Qin LI Yanyan YU Aizhi SUN Yating LIN Wenqi JIANG Yunli LUO 2019Science China Earth Sciences2019,62,8:3
15Selective laser melting of dense and crack-free AlCoCrFeNi_(2.1) eutectic high entropy alloy: Synergizing strength and ductility显示文摘Additively manufactured high-entropy alloys generally suffer from low strength and/or poor ductility.In this work,by leveraging the good castability of eutectic high entropy alloys and high cooling rate of selective laser melting(SLM),we report a nearly fully dense and crack-free as-SLM AlCoCrFeNi_(2.1) eutectic high entropy alloy with an exceptional strength-ductility synergy,showing an ultrahigh yield strength of 982.1±35.2 MPa and an ultimate tensile strength of 1322.8±54.9 MPa together with an elongation to fracture of 12.3±0.5%.Such strength-ductility enhancement is owing to the heterogeneous eutectic microstructure consisting of the columnar,equiaxed,and“L-shape”cells with much refined sizes down to nanoscales.The morphology of cells in the transition zone is related to the misorientation between the growth direction of adjacent layers.This heterogeneous eutectic microstructure is the result of the graingrowth behavior dominated by the mechanisms of the epitaxial growth and growth of heterogeneous nuclei in SLM.Our current results provide a new methodology for the future design of ultrahigh-strength and ductile SLM-fabricated metallic materials including HEAs,and other printable alloys for various structural applications.Lin He Shiwei Wu Anping Dong Haibin Tang Dafan Du Guoliang Zhu Baode Sun Wentao Yan 2022Journal of Materials Science & Technology2022,,22:2
16Effects of AlN on the densification and mechanical properties of pressureless-sintered SiC ceramics显示文摘In the present work, Si C ceramics was fabricated with Al N using B_4 C and C as sintering aids by a solid-state pressureless-sintered method. The effects of Al N contents on the densification, mechanical properties, phase compositions, and microstructure evolutions of as-obtained Si C ceramics were thoroughly investigated. Al N was found to promote further densification of the Si C ceramics due to its evaporation over 1800 °C,transportation, and solidification in the pores resulted from Si C grain coarsening. The highest relative density of 99.65% was achieved for Si C sample with 15.0 wt% Al N by the pressureless-sintered method at 2130 °C for 1 h in Ar atmosphere. Furthermore, the fracture mechanism for Si C ceramics containing Al N tended to transfer from single transgranular fracture mode to both transgranular fracture and intergranular fracture modes when the sample with 30.0 wt% Al N sintered at 1900 °C for 1 h in Ar. Also, Si C ceramics with 30.0 wt% Al N exhibited the highest fracture toughness of 5.23 MPa m^(1/2) when sintered at 1900 °C.Qisong Li Yujun Zhang Hongyu Gong Haibin Sun Yanxia Zhai Weiya Zhu Jie Jing 2016Progress in Natural Science:Materials International2016,26,1:2
17Analysis of bending on the front end of sheet during hot rolling显示文摘The analysis of bending in finishing rolling was performed. An asymmetrical rolling force model was established, and the upper and lower neutral points were determined. The bending which resulted from the asymmetrical rolling force at the roll gap was studied and related flexibility equations were proposed according to elastic mechanics. Moreover, material mechanics was used to analyze the effects of temperature difference and self-weight on the bending out of the roll gap, and the flexibility equations were constructed. The main factors on bending were summed up, and the bending rule in the rolling could be obtained. In addition practical calculation was made with the production data of ribbon steel from Laiwu Iron & Steel Group Co. Ltd.Jiquan Sun Haibin Zhang Quancheng Yu 2006Journal of University of Science and Technology Beijing2006,13,1:2
18Biodegradation of pyrene by Phanerochaete chrysosporium and enzyme activities in soils:Effect of SOM,sterilization and aging显示文摘The impacts of soil organic matter(SOM), aging and sterilization on the production of lignin peroxidase(LiP) and manganese peroxidase(MnP) by Phanerochaete chrysosporium during the biodegradation of pyrene in soils were investigated. The biodegradation of pyrene by P. chrysosporium decreased with increasing SOM content, whereas the maximum activities of LiP and MnP increased, which indicates that SOM outweighed pyrene in controlling enzyme production. Sterilization enhanced the degradation of pyrene due to the elimination of competition from indigenous microbes, whereas aging led to a reduction in the degradation of pyrene primarily through changes in its sorbed forms. Both sterilization and aging could reduce SOM content and alter its structure, which also influenced the bioavailability of pyrene and the enzyme activity. The sterilization and aging processes caused changes in the degradation of pyrene, and the enzyme activities were greater in soils with high SOM contents. MnP was related to the degradation of pyrene to a greater extent, whereas LiP was more related to the decomposition of SOM.Cuiping Wang Hongwen Sun Haibin Liu Baolin Wang 2014Journal of Environmental Sciences2014,26,5:2
19Study of seasonal snow cover influencing the ground thermal regime on western flank of Da Xing'anling Mountains,northeastern China显示文摘Although many studies relevant to snow cover and permafrost have focused on alpine, arctic, and subarctic areas, there is still a lack of understanding of the influences of seasonal snow cover on the thermal regime of the soils in permafrost regions in the mid-latitudes and boreal regions, such as that on the western flank of the Da Xing'anling(Hinggan) Mountains, northeastern China. This paper gives a detailed analysis on meteorological data series from 2001 to 2010 provided by the Gen'he Weather Station, which is located in a talik of discontinuous permafrost zone and with sparse meadow on the observation field. It is inferred that snow cover is important for the ground thermal regime in the middle Da Xing'anling Mountains. Snow cover of 10-cm in thickness and five to six months in duration(generally November to next March) can reduce the heat loss from the ground to the atmosphere by 28%, and by 71% if the snow depth increases to 36 cm. Moreover, the occurrence of snow cover resulted in mean annual ground surface temperatures 4.7–8.2 °C higher than the mean annual air temperatures recorded at the Gen'he Weather Station. The beginning date for stable snow cover establishment(SE date) and the initial snow depth(SDi) also had a great influences on the ground freezing process. Heavy snowfall before ground surface freeze-up could postpone and retard the freezing process in Gen'he. As a result, the duration of ground freezing was shortened by at least 20 days and the maximum depth of frost penetration was as much as 90 cm shallower.XiaoLi Chang HuiJun Jin YanLin Zhang HaiBin Sun 2015Research in Cold and Arid Regions2015,7,6:2
20Synthesis of a Novel Co-B/CTAB Catalyst via Solid-state-reaction at Room Temperature for Hydrolysis of Ammonia-borane显示文摘Cobalt-boride(Co-B)is emerging as one of the promising materials in the base-hydrolytic dehydrogena-tion of ammonia-borane(AB).In order to avoid the low specific area and poor catalytic capacity of Co-B catalyst caused by aggregation arising from the strong reducing property and rapid reaction condensation of sodium borohy-dride(NaBHa),novel cobalt boride/cetyltrimethylammonium bromide(Co-B/CTAB)catalyst was obtained via solid-state grinding at room temperature,and the catalyst was further characterized by XRD,SEM,XPS and BET.The hydrogen generation rate(HGR)was then determined by the hydrolysis reaction of AB.The SEM images indicate that a lot of irregular folds and curled edges are formed on the sample with a maximum surface area of 145.57 m2/g,thus possibly resulting in the high hydrogen production(HGR was 10.68 L.minlg),which may be attributed to CTAB that provide favorable large specific surface area and abundant porous structure.Additionally,catalyst will not be affected by solvants during solid-state reaction.As a diluent,the surfactant CTAB hindered the reaction rate of sodium borohydride reduction to cobalt boride and obtained the novel catalyst with a large specific surface area.HU Haibin LONG Bo JIANG Yifan SUN Shichang Ibrahim LAWAN ZHOU Weiming- ZHANG Mingxin WANG Liwei ZHANG Fan YUAN Zhanhui 2020Chemical Research in Chinese Universities2020,36,6:2
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