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| 1 | Viral effector protein manipulates host hormone signaling to attract insect vectors显示文摘 | Dewei Wu Tiancong Qi Wan-Xiang Li Haixia Tian Hua Gao Jiaojiao Wang Jin Ge Ruifeng Yao Chunmei Ren Xian-Bing Wang Yule Liu Le Kang Shou-Wei Ding Daoxin Xie | 2017 | Cell Research2017，27，3： | 20 |
| 2 | The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala显示文摘The short allele of the serotonin-transporter gene is associated with higher risk for anxiety and depression in Caucasians, but this association is still unclear in Asians. Here, we addressed this issue using behavioral and multi-modal MRI approaches in a large group of healthy Han Chinese participants (n = 233). In contrast to findings in Caucasians, we found that long-allele (L) carriers had higher anxiety scores. In another group (n = 64) experiencing significant levels of depression or anxiety, the L-allele frequency was also significantly higher. In healthy participants, L-carriers had reduced functional and anatomical connectivity between the amygdala and prefrontal cortex (PFC), which was correlated with anxiety or depression scores. Our findings demonstrated that in Chinese Han participants, in contrast to Caucasians, the L-allele confers vulnerability to anxiety or depression and weakens top-down emotional control between the PFC and amygdala. Therefore, ethnic background should be taken into account in gene-related studies and their potential clinical applications. | Haixia Long Bing Liu Bing Hou Chao Wang Jin Li Wen Qin Dawei Wang Yuan Zhou Keith M. Kendrick Chunshui Yu Tianzi Jiang | 2013 | Neuroscience Bulletin2013，29，1： | 9 |
| 3 | Cross-Scale Synthesis of Organic High-k Semiconductors Based on Spiro-Gridized Nanopolymers显示文摘High dielectric constants in organic semiconductors have been identified as a central challenge for the improvement in not only piexoelectric,preolecric,and freeltric efcts but also photoclecric conversion eficiency in OPVs,carrier mobility in OFETS,and charge density in charge-trapping memories.Herein,we report an ultralong persistence length(≈41 nm)efet of spiro-fused organic nanopolymers on dielectric properties,together with excitonic and charge carrier behaviors.The state-of-the-art nanopolymers,namely,nanopolyspirogrids(NPSGs),are synthesized via the simple crossscale Friedel-Crafts polygridlization of AjB-type nanomonomers.The high dielectric constant(k=8.43)of NPSG is firstly achieved by locking spiro-polygridization efect that results in the enhancement of dipole polarization.When doping into a polystyrene-based dielectric layer,such a high-k feature of NPSG increases the feld-ffct carrier mobility from 0.20 to 0.90cm^(2)Vl s'in pentacene OFET devices.Meanwhile,amorphous NPSG film exhibits an ultralow energy disorder(<50 meV)for an exellent zero-field hole mobility of 3.94×10^(-1)cm^(2)V^(-1)s^(-1).surpassing most of the amorphousπconjugated polymers Onganic nanopolymers with high dielectric constants open a new way to break through the bottleneck of eficiency and multifunctionality in the blueprint of the fourth generation semiconductors. | Dongqing Lin Wenhua Zhang Hang Yin Haixia Hu Yang Li He Zhang Le Wang Xinmiao Xie Hongkai Hu Yongxia Yan Haifeng Ling Jin'an Liu Yue Qian Lei Tang Yongxia Wang Chaoyang Dong Linghai Xie Hao Zhang Shasha Wang Ying Wei Xuefeng Guo Dan Lu Wei Huang | 2022 | Research2022，，2： | 3 |
| 4 | Applications of Nanobiomaterials in the Therapy and Imaging of Acute Liver Failure显示文摘Acute liver failure(ALF),a fatal clinical disease featured with overwhelming hepatocyte necrosis,is a grand challenge in global health.However,a satisfactory therapeutic option for curing ALF is still absent,other than liver transplantation.Nanobiomaterials are currently being developed for the diagnosis and treatment of ALF.The liver can sequester most of nanoparticles from blood circulation,which becomes an intrinsic superiority for nanobiomaterials targeting hepatic diseases.Nanobiomaterials can enhance the bioavailability of free drugs,thereby significantly improving the therapeutic effects in ALF.Nanobiomaterials can also increase the liver accumulation of therapeutic agents and enable more effective targeting of the liver or specific liver cells.In addition,stimuli-responsive,optical,or magnetic nanomaterials exhibit great potential in the therapeutical,diagnostic,and imaging applications in ALF.Therefore,therapeutic agents in combination with nanobiomaterials increase the specificity of ALF therapy,diminish adverse systemic effects,and offer a multifunctional theranostic platform.Nanobiomaterial holds excellent significance and prospects in ALF theranostics.In this review,we summarize the therapeutic mechanisms and targeting strategies of various nanobiomaterials in ALF.We highlight recent developments of diverse nanomedicines for ALF therapy,diagnosis,and imaging.Furthermore,the challenges and future perspectives in the theranostics of ALF are also discussed. | Yuanyuan Jin Haixia Wang Ke Yi Shixian Lv Hanze Hu Mingqiang Li Yu Tao | 2021 | Nano-Micro Letters2021，13，2： | 3 |
| 5 | A drug-loaded composite coating to improve osteogenic and antibacterial properties of Zn-1Mg porous scaffolds as biodegradable bone implants显示文摘Zinc(Zn)alloy porous scaffolds produced by additive manufacturing own customizable structures and biodegradable functions,having a great application potential for repairing bone defect.In this work,a hydroxyapatite(HA)/polydopamine(PDA)composite coating was constructed on the surface of Zn-1Mg porous scaffolds fabricated by laser powder bed fusion,and was loaded with a bioactive factor BMP2 and an antibacterial drug vancomycin.The microstructure,degradation behavior,biocompatibility,antibacterial performance and osteogenic activities were systematically investigated.Compared with as-built Zn-1Mg scaffolds,the rapid increase of Zn2+,which resulted to the deteriorated cell viability and osteogenic differentiation,was inhibited due to the physical barrier of the composite coating.In vitro cellular and bacterial assay indicated that the loaded BMP2 and vancomycin considerably enhanced the cytocompatibility and antibacterial performance.Significantly improved osteogenic and antibacterial functions were also observed according to in vivo implantation in the lateral femoral condyle of rats.The design,influence and mechanism of the composite coating were discussed accordingly.It was concluded that the additively manufactured Zn-1Mg porous scaffolds together with the composite coating could modulate biodegradable performance and contribute to effective promotion of bone recovery and antibacterial function. | Zhenbao Zhang Aobo Liu Jiadong Fan Menglin Wang Jiabao Dai Xiang Jin Huanze Deng Xuan Wang Yijie Liang Haixia Li Yantao Zhao Peng Wen Yanfeng Li | 2023 | Bioactive Materials2023，，9： | 2 |
| 6 | Determination of strain criterion of Portevin-Le chatelier effect for aluminum alloy sheets 显示文摘 | Wan Min Han Jinquan Jin Haixia | 2006 | Transactions of Nonferrous Metals Society of China2006，16，3： | 1 |
| 7 | Conversion of rat embryonic stem cells into neural precursors in chemical-defined medium显示文摘 | Xinrong Peng Haixia Gao Ying Wang Baotian Yang Tao Liu Yan Sun Huajun Jin Lihua Jiang Linfang Li Mengchao Wu Qijun Qian | 2013 | Biochemical and Biophysical Research Communications2013，，： | 1 |
| 8 | Porcine skeletal muscle differentially expressed gene ATP5B : molecular characterization, expression patterns, and association analysis with meat quality traits显示文摘 | Haixia Xu Yongjie Xu Xiaojuan Liang Yanbo Wang Fangfang Jin Dengying Liu Yun Ma Hongyu Yuan Xinqiang Song Wenxian Zeng | 2013 | Mammalian Genome2013，，3： | 1 |
| 9 | Kinetics and mechanisms of reactions for hydrated electron with chlorinated benzenes in aqueous solution显示文摘在使氯化的苯(CBzs ) 和含水的电子之间的反应(e aq ) 被电子横梁(EB ) 和激光闪光光分解作用(LFP ) 实验调查。在 EB 照耀,照耀剂量的效果,起始的集中和移动上的 Cl 原子的数字下面,效率进一步被检验。在 10 kGy, mono-CB, 1,3-diCB, 1,2-diCB 和 1,4-diCB 的移动效率分别地是 41.2% , 87.2% , 84.0% ,和 84.1% 。当照耀剂量是 50 kGy 时,移动效率分别地增加了到 47.4% , 95.8% , 95.0% ,和 95.2% 。CBzs 答案的照耀看了那越高起始的集中,越多降低 CBzs 的百分比移动。除了这, 1,2-dichlorobenzene (1,2-diCB ) 的 dechlorination 效率, 1,3-dichlorobenzene (1,3-diCB ) 和 1,4-dichlorobenzene (1,4-diCB ) 比 chlorobenzene (mono-CB ) 的高得多。反应的动力学与毫微秒 LFP 被完成。在 e 有 mono-CB, 1,2-diCB, 1,3-diCB 和 1,4-diCB 的 aq 是(5.3? | Haixia YUAN Huxiang PAN Jin SHI Hongjing LI Wenbo DONG | 2015 | Frontiers of Environmental Science & Engineering2015，9，4： | 1 |
| 10 | Role of prostaglandin D2/CRTH2 pathway on asthma exacerbation induced by A spergillus fumigatus显示文摘 | Haixia Liu Mingrui Zheng Jianou Qiao Yajie Dang Pengyu Zhang Xianqiao Jin | 2014 | Immunology2014，，1： | 1 |
| 11 | MdWRKY11 improves copper tolerance by directly promoting the expression of the copper transporter gene MdHMA5显示文摘Overuse of fungicides and fertilizers has resulted in copper(Cu)contamination of soils and toxic levels of Cu in apple fruits.To breed Cu-resistant apple(Malus domestica)cultivars,the underlying molecular mechanisms and key genes involved in Cu resistance must be identified.Here,we show that MdWRKY11 increases Cu tolerance by directly promoting the transcription of MdHMA5.MdHMA5 is a Cu transporter that may function in the storage of excess Cu in root cell walls and stems for Cu tolerance in apple.The transcription factor MdWRKY11 is highly induced by excess Cu.MdWRKY11 overexpression in transgenic apple enhanced Cu tolerance and decreased Cu accumulation.Apple calli transformed with an MdWRKY11-RNAi construct exhibited the opposite phenotype.Both an in vivo chromatin immunoprecipitation assay and an in vitro electrophoretic mobility shift assay indicated that MdWRKY11 binds to the promoter of MdHMA5.Furthermore,MdWRKY11 promoted MdHMA5 expression in transgenic apple plants,as revealed by quantitative PCR.Moreover,inhibition of MdWRKY11 expression by RNA interference led to a significant decrease in MdHMA5 transcription.Thus,MdWRKY11 directly regulates MdHMA5 transcription.Our work resulted in the identification of a novel MdWRKY11-MdHMA5 pathway that mediates Cu resistance in apple. | Kun Shi Xuan Liu Yunpeng Zhu Yixue Bai Dongqian Shan Xiaodong Zheng Lin Wang Haixia Zhang Chanyu Wang Tianci Yan Fangfang Zhou Zehui Hu Yanzhao Sun Yan Guo Jin Kong | 2020 | Horticulture Research2020，7，1： | 1 |
| 12 | Isobolographic analysis of theantinociceptive interactions betwee ketoprofen and paracetamol显示文摘 | QIU Haixia LIU Jin KONG Hui | 2007 | Euro-pean Journal of Pharmacology2007，557，： | 1 |
| 13 | Early protective effect of total hypoxic preconditioning on rats against systemic injury from hemorrhagic shock and resuscitation显示文摘 | Zeyan Duan Lei Zhang Jin Liu Xujin Xiang Haixia Lin | 2012 | Journal of Surgical Research2012，，： | 1 |
| 14 | Influence of Ga-doping on the thermoelectric properties of Bi_(2-x)Ga_xTe_(2.7)Se_(0.3) alloy显示文摘Bi(2-x)GaxTe2.7Se0.3(x=0, 0.04, 0.08, 0.12) alloys were fabricated by vacuum melting and hot pressing technique. The structure of the samples was evaluated by means of X-ray diffraction. The peak shift toward higher angle can be observed by Ga-doping. The effects of Ga substitution for Bi on the electrical and thermal transport properties were investigated in the temperature range of 300–500 K. The power factor values of the Ga-doped samples are obviously improved in the temperature range of 300–440 K. Among all the samples, the Bi(2-x)GaxTe2.7Se0.3(x=0.04) sample showed the lowest thermal conductivity near room temperature and the maximum ZT value reached 0.82 at 400 K. | Xingkai Duan Konggang Hu Shifeng Ding Dahu Man Haixia Jin | 2015 | Progress in Natural Science:Materials International2015，25，1： | 1 |
| 15 | Every Little Effort Helps Eternal Friendship——Notes of the Visit to Binxian in Shaanxi Province by Japanese High School Students from Naganoken显示文摘A 12-member delegation of Japanese high school students from Naganoken,headed by Mr.Hiroji Izawa,Councilman of Japan-China Exchange Association in Naganoken,visited Binxian in Shaanxi Province from March 24 to 25.As a staff member of CAFIU, | Wu Jin You Haixia | 2012 | International Understanding2012，，1： | 0 |
| 16 | Authors' response to “Maternal age as a potential explanation of the role of the L allele of the serotonin transporter gene in anxiety and depression in Asians”显示文摘In the letter to the editor,Dr.Comings et al.proposed a potential explanation of our findings that the L allele rather than S allele of 5-HTTLPR was associated with higher anxiety levels and reduced amygdala-prefrontal cortex(PFC)connectivity in Han Chinese[1],which demonstrated an‘allele reversal’in the genetics of the 5-HTTLPR gene in Asians | Haixia Long Bing Liu Bing Hou Chao Wang Jin Li Tianzi Jiang | 2014 | Neuroscience Bulletin2014，30，3： | 0 |
| 17 | Some Thoughts on Science-based Botanical Garden Establishment显示文摘Through analysis of the historical and present development of botanical gardens, both domestic and international, with particular focus on botanical garden practices within the Chinese Academy of Sciences (CAS), the authors propose that science-based botanical gardens (which differ from common public gardens), should be founded on plant diversity inventory and ex-situ conservation of wild plant species. Efforts should be directed to rarer species from biodiversity-rich areas and biodiversity hotspots, utilizing cutting-edge technologies to effectively preserve germplasm in living collections. Science-based botanical garden management should be directed by sound scientific evaluation of plant resources and guaranteed by innovative operational mechanisms. Science-based botanical gardens should also emphasize the establishment of identifiable and specialized living collections, research platforms and recruitment of qualified experts. In addition to curating living specimens, science-based botanical gardens should pursue research and development of new plant varieties or patents based on their plant collections, thus providing continual support to bio-industry. | Lou Zhiping Miao Haixia Chen Jin Su Ronghui | 2010 | Bulletin of the Chinese Academy of Sciences2010，24，4： | 0 |
| 18 | Developmental distribution pattern of metabotropic glutamate receptor 5 in prenatal human hippocampus显示文摘(mGluR5 ) 客观 Metabotropic glutamate 受体 5 在出生前、出生后的啮齿类动物大脑在活跃神经发生的地区被集中并且在神经发生的规定起一个重要作用。然而,很少在出生前的人的大脑对 mGluR5 被知道。这里,我们试图在人的胎儿的马头鱼尾的怪兽探索表示模式和 mGluR5 的细胞的分发。34 个人的胎儿根据 gestational 被划分成四个组的方法变老:911, 1416, 2224 和 3236 个星期。马头鱼尾的怪兽外面被把并且准备。蛋白质和 mGluR5 的 mRNA 表示被西方的污点和 immunohistochemistry 或即时 PCR 评估。mGluR5 的细胞的分发与双 labeling immunofluorescence 被观察。结果 mGluR5 mRNA 和蛋白质被即时 PCR 和 immunoblotting 在出生前的人的马头鱼尾的怪兽检测,并且表示层次随着时间的过去逐渐地增加了。immunohistochemistry 结果与 immunoblotting 一致并且证明 mGluR5 immunoreactivity 主要是在内部边缘的地区(IMZ ) 的现在,海马趾的板(HP ) 和室的地区(VZ ) 。双 labeling immunofluorescence 证明 mGluR5 在神经干细胞是在场的(nestin 积极) ,神经母细胞(DCX 积极) 并且成熟神经原(NeuN 积极) ,然而并非在典型星形细胞(GFAP 积极) 。房间共同表示 mGluR5 和 nestin 主要在 24 个星期在 11 个星期,在 16 个星期的所有层,和 CA1 位于 IMZ, HP 和 subplate。当开发继续了, mGluR5/nestin 双 positive 房间的数字逐渐地减少了以便仅仅有在 32 个星期的双 labeled 房间的一把。然而, mGluR5/DCX 双 positive 房间仅仅在 11 个星期在 HP, IZ 和 IMZ 被发现。由神经干细胞,神经母细胞和神经原的 mGluR5 表示的模式在人的海马趾的开发的规定为 mGluR5 的角色提供重要解剖证据的结论。 | Pengbo Yang Junfeng Zhang Lingyu Zhao Qian Jiao Hui Jin Xinli Xiao Haixia Zhang Ming Hu HaiXia Lu Yong Liu | 2012 | Neuroscience Bulletin2012，28，6： | 0 |
| 19 | A Review of Seismicity in 2016显示文摘1 SURVEY OF GLOBAL SEISMICITY A total of 17 strong earthquakes with MS≥7.0 occurred in 2016(by the end of December31,2016)throughout the world,according to the China Seismic Network.Among them,one earthquake with M_S8.0 occurred on November 13,2016 in New Zealand(Fig.1).The 2016New Zealand M_S8.0 earthquake(M_W7.8 measured by USGS)was the strongest | Li Zhichao Song Jin Jiang Xianghua Zang Yang Yang Wen Yao Qi Shi Haixia Han Yanyan Meng Lingyuan Zhou Longquan | 2017 | Earthquake Research in China2017，31，1： | 0 |
| 20 | Revealing the correlation between adsorption energy and activation energy to predict the catalytic activity of metal oxides for HMX using DFT显示文摘Traditional selection of combustion catalysis is time-consuming and labor-intensive.Theoretical calculation is expected to resolve this problem.The adsorption energy of HMX and O atoms on 13 metal oxides was calculated using DMol3,since HMX and O are key substances in decomposition process.And the relationship between the adsorption energy of HMX,O on metal oxides(TiO_(2),Al_(2)O_(3),PbO,CuO,Fe_(2)O_(3),Co_(3)O_(4),Bi_(2)O_(3),NiO)and experimental T30 values(time required for the decomposition depth of HMX to reach 30%)was depicted as volcano plot.Thus,the T30 values of other metal oxides was predicted based on their adsorption energy on volcano plot and validated by previous experimental data.Further,the adsorption energy of HMX on ZrO_(2)and MnO_(2)was predicted based on the linear relationship between surface energy and adsorption energy,and T30 values were estimated based on volcano plot.The apparent activation energy data of HMX/MgO,HMX/SnO_(2),HMX/ZrO_(2),and HMX/MnO_(2)obtained from DSC experiments are basically consistent with our predicted T30 values,indicating that it is feasible to predict the catalytic activity based on the adsorption calculation,and it is expected that these simple structural properties can predict adsorption energy to reduce the large quantities of computation and experiment cost. | Xiurong Yang Chi Zhang Wujing Jin Zhaoqi Guo Hongxu Gao Shiyao Niu Fengqi Zhao Bo Liu Haixia Ma | 2024 | Defence Technology(防务技术)2024，31，1： | 0 |
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