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| 1 | Control of Grain Size and Weight by the OsMKKK10-OsM KK4-OsMAPK6 Signaling Pathway in Rice显示文摘谷物尺寸是在庄稼决定谷物产量的关键农学的特点之一。然而,在庄稼位于谷物尺寸控制下面的机制留下逃犯。这里,我们证明断然表明小径的 OsMKKK10-OsMKK4-OsMAPK6 在米饭调整谷物尺寸和重量。在米饭,当组成地活跃的 OsMKKK10 (CA-OsMKKK10 ) 的 overexpression 导致大、重的谷物,长圆锥花序,和高植物时, OsMKKK10 功能的损失导致小、轻的谷物,短圆锥花序,和半矮子植物。OsMKKK10 交往与并且 phosphorylates OsMKK4。我们识别了 OsMKK4 gain-of-function 异种(large11-1D )? 那生产大、重的谷物。OsMKK4 large11-1D 等位基因编码的 A227T 比 OsMKK4 举办更强壮的 kinase 活动。植物 overexpressing OsMKK4 (OsMKK4-DD ) 的一种组成地活跃的形式也生产大谷物。进一步生物化学、基因的分析表明 OsMKKK10, OsMKK4,和 OsMAPK6 在一条普通小径工作控制谷物尺寸。一起拿,我们的学习在米饭为谷物尺寸和重量的 OsMKKK10-OsMKK4-OsMAPK6 调停串联的控制建立一个重要基因、分子的框架。 | Ran Xu Penggen Duan Haiyue Yu Zhengkui Zhou Baolan Zhang Ruci Wang Jing Li Guozheng Zhang Shangshang Zhuang Jia Lyu Na Li Tuanyao Chai Zhixi Tian Shanguo Yao Yunhai Li | 2018 | Molecular Plant2018,11,6: | 33 |
| 2 | Research of Damping System Characteristics for HVDC Converter Valves显示文摘直流换流阀阻尼系统由饱和电抗器铁心电阻和晶闸管级阻尼电阻2部分组成。该文提出了饱和电抗器动态电感和铁心电阻分析计算方法,建立了铁心电阻与磁通密度的函数关系及饱和电抗器等值电路模型。通过对高频电压源激励下端口伏安特性理论计算结果与试验测试结果对比,验证了模型的正确性。提出了阻尼系统抑制振荡电流性能分析方法,给出了晶闸管第1个电流波谷值处于局部极限值的阻尼系统配置方案;分析了阻尼系统冲击电压下辅助限制过电压性能;提出了阻尼系统损耗计算方法,研究了换流阀不同运行状态下的损耗性能。 | LIU Jie ZHANG Jing CAO Junzheng YU Haiyu WEI Xiaoguang XI Hexun | 2012 | 中国电机工程学报2012,32,30: | 6 |
| 3 | ETCM v2.0:An update with comprehensive resource and rich annotations for traditional Chinese medicine显示文摘Existing traditional Chinese medicine(TCM)-related databases are still insufficient in data standardization,integrity and precision,and need to be updated urgently.Herein,an Encyclopedia of Traditional Chinese Medicine version 2.0(ETCM v2.0,http://www.tcmip.cn/ETCM2/front/#/)was constructed as the latest curated database hosting 48,442 TCM formulas recorded by ancient Chinese medical books,9872 Chinese patent drugs,2079 Chinese medicinal materials and 38,298 ingredients.To facilitate the mechanistic research and new drug discovery,we improved the target identification method based on a two-dimensional ligand similarity search module,which provides the confirmed and/or potential targets of each ingredient,as well as their binding activities.Importantly,five TCM formulas/Chinese patent drugs/herbs/ingredients with the highest Jaccard similarity scores to the submitted drugs are offered in ETCM v2.0,which may be of significance to identify prescriptions/herbs/ingredients with similar clinical efficacy,to summarize the rules of prescription use,and to find alternative drugs for endangered Chinese medicinal materials.Moreover,ETCM v2.0 provides an enhanced Java Script-based network visualization tool for creating,modifying and exploring multi-scale biological networks.ETCM v2.0 may be a major data warehouse for the quality marker identification of TCMs,the TCM-derived drug discovery and repurposing,and the pharmacological mechanism investigation of TCMs against various human diseases. | Yanqiong Zhang Xin Li Yulong Shi Tong Chen Zhijian Xu Ping Wang Meng Yu Wenjia Chen Bing Li Zhiwei Jing Hong Jiang Lu Fu Wenjing Gao Yanhua Jiang Xia Du Zipeng Gong Weiliang Zhu Hongjun Yang Haiyu Xu | 2023 | Acta Pharmaceutica Sinica B2023,13,6: | 3 |
| 4 | Rational Design of WO_3 Nanostructures as the Anode Materials for Lithium-Ion Batteries with Enhanced Electrochemical Performance显示文摘A facile, one-step hydrothermal method was employed to synthesize two kinds of WO3 nanostructures. By using different kinds of sylvine, tungsten trioxide(WO3) with different morphologies of microflowers and nanowires was obtained, respectively. The discharge capacities for microflowers and nanowires are 107 and 146 m Ah g-1 after 180 cycles, and their corresponding capacity retentions after the first cycle are 72 and 85 %, respectively. Even at a high current density of 1,600 m Ah g-1, the discharge capacities of WO3 microflowers and nanowires are as high as 433 and557 m Ah g-1 after 40 cycles, in which the current densities were increased stepwise. It is worth mentioned that the rate capability of the nanowires is superior to that of the microflowers. However, the cycle performance of the microflowers is better than nanowires, revealing that the morphology and structure of the as-synthesized WO3 products can exert great influence on the electrochemical performances. | Yang Liu Yang Jiao Haiyue Zhou Xiang Yu Fengyu Qu Xiang Wu | 2015 | Nano-Micro Letters2015,7,1: | 2 |
| 5 | Rare-earth single atom based luminescent composite nanomaterials:Tunable full-color single phosphor and applications in WLEDs显示文摘High-quality single-component white phosphors are instrumental in realizing high-efficiency devices.Rare earth fluorides and carbon quantum dots have great potential in the white light-emitting diode(WLED)field due to their unique advantages.Here,Rare-earth single atom based NaGdF4:Tb^(3+)/Eu^(3+)@C:N/Eu^(3+)single phosphor with tunable full-color luminescence was reported.The results of density functional theory(DFT)calculation and experimental characterization show that C atoms cannot be replaced by Eu^(3+),but C atoms are more favorable for anchoring Eu^(3+)single atoms.The DFT was employed to optimize the structures of the C:N/Eu^(3+)and NaGdF4:Tb^(3+)/Eu^(3+),and calculate the work function,optical properties,and charge density difference.The obtained tunable full-color single phosphor can emit stable light from blue to red or even white.The constructed WLED devices also have stable and excellent color performance,that is,a color rendering index of up to 95 and a lower color temperature,and it has broad application possibilities in WLEDs. | Shan Bao Haiyue Yu Guoyang Gao Hongyang Zhu Dingsheng Wang Peifen Zhu Guofeng Wang | 2022 | Nano Research2022,15,4: | 2 |
| 6 | MicroRNA-activated hydrogel scaffold generated by 3D printing accelerates bone regeneration显示文摘Bone defects remain a major threat to human health and bone tissue regeneration has become a prominent clinical demand worldwide.The combination of microRNA(miRNA)therapy with 3D printed scaffolds has always posed a challenge.It can mimic physiological bone healing processes,in which a biodegradable scaffold is gradually replaced by neo-tissue,and the sustained release of miRNA plays a vital role in creating an optimal osteogenic microenvironment,thus achieving promising bone repair outcomes.However,the balance between two key factors-scaffold degradation behavior and miRNA release profile-on osteogenesis and bone formation is still poorly understood.Herein,we construct a series of miRNA-activated hydrogel scaffolds(MAHSs)generated by 3D printing with different crosslinking degree to screened the interplay between scaffold degradation and miRNA release in the osteoinduction activity both in vitro and in vivo.Although MAHSs with a lower crosslinking degree(MAHS-0 and MAHS-0.25)released a higher amount of miR-29b in a sustained release profile,they degraded too fast to provide prolonged support for cell and tissue ingrowth.On the contrary,although the slow degradation of MAHSs with a higher crosslinking degree(MAHS-1 and MAHS-2.5)led to insufficient release of miR-29b,their adaptable degradation rate endowed them with more efficient osteoinductive behavior over the long term.MAHS-1 gave the most well-matched degradation rate and miR-29b release characteristics and was identified as the preferred MAHSs for accelerated bone regeneration.This study suggests that the bio-adaptable balance between scaffold degradation behavior and bioactive factors release profile plays a critical role in bone regeneration.These findings will provide a valuable reference about designing miRNAs as well as other bioactive molecules activated scaffold for tissue regeneration. | Ting Pan Wenjing Song Hongbao Xin Haiyue Yu He Wang Dandan Ma Xiaodong Cao Yingjun Wang | 2022 | Bioactive Materials2022,7,4: | 2 |
| 7 | SbPS_(4):A novel anode for high-performance sodium-ion batteries显示文摘With the in-depth research of sodium-ion batteries(SIBs),the development of novel sodium-ion anode material has become a top priority.In this work,tube cluster-shaped SbPS_(4)was synthesized by a high-temperature solid phase reaction.Then the typical short tubular ternary thiophosphate SbPS_(4)compounded with graphene oxide(SbPS_(4)/GO)was successfully synthesized after ultrasonication and freeze-drying.SbPS_(4)shows a high theoretical specific capacity(1335 mAh/g)according to the conversion-alloying dual mechanisms.The unique short tube inserted in the spongy graphene structure of SbPS_(4)/GO results in boosting the Na ions transport and alleviating the huge volume change in the charging and discharging processes,improving the sodium storage performance.Consequently,the tubular SbPS_(4)compounded with 10%GO provides an outstanding capacity of 359.58 mAh/g at 500 mA/g.The result indicates that SbPS_(4)/GO anode has a promising application potential for SIBs. | Miao Yang Zhonghui Sun Ping Nie Haiyue Yu Chende Zhao Mengxuan Yu Zhongzhen Luo Hongbo Geng Xinglong Wu | 2022 | Chinese Chemical Letters2022,33,1: | 1 |
| 8 | The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite显示文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. | Xianyong Bai Hui Tian Yuanyong Deng Zhanshan Wang Jianfeng Yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang Yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao Yang Jiaben Lin Ziyao Hu Qian Song Zihao Yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi Yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang | 2023 | Research in Astronomy and Astrophysics2023,23,6: | 1 |
| 9 | Antimicrobial activity of extract and two alka- loids from traditional Chinese medicinal plant stephania dielsiana 显示文摘 | Deng Yecheng Yu Yanzhen Luo Haiyu | 2011 | Food Chemistry2011,124,4: | 1 |
| 10 | Design of novel structure current transformer with shielding coils for overcoming the saturation of core显示文摘 | YU Haiyu YUAN Jiansheng ZOU Jun | 2006 | IEEE Transactions on Magnetics2006,42,4: | 1 |
| 11 | Analysis of genetic diversity in cytoplasmic male sterility, and association of mitochondrial genes with petaloid-type cytoplasmic male sterility in tuber mustard (Brassica juncea var. tumida Tsen et Lee)显示文摘 | Xiaolin Yu Haiyu Lu Gang Lu Zhujun Chen Jiashu Cao Yutaka Hirata | 2010 | Molecular Biology Reports2010,,2: | 1 |
| 12 | Sodium-based dual-ion batteries via coupling high-capacity selenium/graphene anode with high-voltage graphite cathode显示文摘Dual ion batteries(DIBs) exhibit broad application prospects in the field of electrical energy storage(EES)devices with excellent properties,such as high voltage,high energy density,and low cost.In the graphitebased DIBs,high voltage is needed to store enough anions with the formation of anion intercalation compound XCn(X=AlCl4-,PF6-,TFSI-,etc.).Hence,it is difficult for graphite-based DIBs to match proper anodes and electrolytes.Here,an Se/graphene composite is prepared via a convenient method,and assembled into a dual-ion full battery(DIFB) as anode with graphite cathode and 1 mol/L NaPF6 in EC:EMC(1:1,v:v).This DIFB has achieved a high discharge capacity of 75.9 mAh/g and high medium output voltage of 3.5 V at 0.1 A/g.Actually,the suitable anode materials,such as the present Se/graphene composite,are extremely important for the development and application of graphite-based DIBs.This study is enlightening for the design of future low-cost EES devices including graphite-based DIBs. | Xiankun Hou Wenhao Li Yingying Wang Shaofang Li Yunfeng Meng Haiyue Yu Baokuan Chen Xinglong Wu | 2020 | Chinese Chemical Letters2020,31,9: | 1 |
| 13 | Technical innovations in ear reconstruction using a skin expander with autogenous cartilage grafts显示文摘 | Yu Dashan Jiang Haiyue Yang Qinghua Pan Bo Lin Lin Wang Tailing Wang Yanmei Qin Xiao Zhuang Hongxing | 2008 | Journal of Plastic, Reconstructive & Aesthetic Surgery2008,,: | 1 |
| 14 | Distributed consensus-based Kalman filtering in sensor networks with quantised communications and random sensor failures显示文摘 | Song Haiyu Yu Li Zhang Wenan | 2014 | IET Signal Processing2014,8,2: | 1 |
| 15 | Design of novel structure current transformer with shielding eoils for overcoming the saturation of core显示文摘 | YU Haiyu YUAN Jiansheng ZOU Jun | 2006 | IEEE Trans on Magnetics2006,42,4: | 1 |
| 16 | A homologous and molecular dual-targeted biomimetic nanocarrier for EGFR-related non-small cell lung cancer therapy显示文摘The abnormal activation of epidermal growth factor receptor(EGFR)drives the development of non-small cell lung cancer(NSCLC).The EGFR-targeting tyrosine kinase inhibitor osimertinib is frequently used to clinically treat NSCLC and exhibits marked efficacy in patients with NSCLC who have an EGFR mutation.However,free osimertinib administration exhibits an inadequate response in vivo,with only~3%patients demonstrating a complete clinical response.Consequently,we designed a biomimetic nanoparticle(CMNP^(@Osi))comprising a polymeric nanoparticle core and tumor cell-derived membrane-coated shell that combines membrane-mediated homologous and molecular targeting for targeted drug delivery,thereby supporting a dual-target strategy for enhancing osimertinib efficacy.After intravenous injection,CMNP^(@Osi)accumulates at tumor sites and displays enhanced uptake into cancer cells based on homologous targeting.Osimertinib is subsequently released into the cytoplasm,where it suppresses the phosphorylation of upstream EGFR and the downstream AKT signaling pathway and inhibits the proliferation of NSCLC cells.Thus,this dual-targeting strategy using a biomimetic nanocarrier can enhance molecular-targeted drug delivery and improve clinical efficacy. | Bin Xu Fanjun Zeng Jialong Deng Lintong Yao Shengbo Liu Hengliang Hou Yucheng Huang Hongyuan Zhu Shaowei Wu Qiaxuan Li Weijie Zhan Hongrui Qiu Huili Wang Yundong Li Xianzhu Yang Ziyang Cao Yu Zhang Haiyu Zhou | 2023 | Bioactive Materials2023,,9: | 1 |
| 17 | Analysis of genetic diversity in cytoplasmic male sterility, and association of mitochondrial genes with petaloid-type cytoplasmic male sterility in tuber mustard (Brassica junceavar, tumida Tsen et Lee) 显示文摘 | XIAOLIN YU HAIYU LU GANG LU | 2010 | Mol Biol Rep2010,37,: | 1 |
| 18 | Design of novel structure current transformer with shielding coils for overcoming the saturation of core 显示文摘 | YU Haiyu YUAN Jiansheng ZOU Jun | 2006 | IEEETransactions on Magnetics2006,42,4: | 1 |
| 19 | Finite-time H ∞ control for a class of discrete-time switched time-delay systems with quantized feedback显示文摘 | Haiyu Song Li Yu Dan Zhang Wen-An Zhang | 2012 | Communications in Nonlinear Science and Numerical Simulation2012,,12: | 1 |
| 20 | Proximal and remote sensing in plant phenomics: 20 years of progress, challenges, and perspectives显示文摘Plant phenomics(PP)has been recognized as a bottleneck in studying the interactions of genomics and environment on plants,limiting the progress of smart breeding and precise cultivation.High-throughput plant phenotyping is challenging owing to the spatio-temporal dynamics of traits.Proximal and remote sensing(PRS)techniques are increasingly used for plant phenotyping because of their advantages in multi-dimensional data acquisition and analysis.Substantial progress of PRS applications in PP has been observed over the last two decades and is analyzed here from an interdisciplinary perspective based on 2972 publications.This progress covers most aspects of PRS application in PP,including patterns of global spatial distribution and temporal dynamics,specific PRS technologies,phenotypic research fields,working environments,species,and traits.Subsequently,we demonstrate how to link PRS to multi-omics studies,including how to achieve multi-dimensional PRS data acquisition and processing,how to systematically integrate all kinds of phenotypic information and derive phenotypic knowledge with biological significance,and how to link PP to multi-omics association analysis.Finally,we identify three future perspectives for PRS-based PP:(1)strengthening the spatial and temporal consistency of PRS data,(2)exploring novel phenotypic traits,and(3)facilitating multi-omics communication. | Haiyu Tao Shan Xu Yongchao Tian Zhaofeng Li Yan Ge Jiaoping Zhang Yu Wang Guodong Zhou Xiong Deng Ze Zhang Yanfeng Ding Dong Jiang Qinghua Guo Shichao Jin | 2022 | Plant Communications2022,3,6: | 1 |