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| 1 | Preharvest long-term exposure to UV-B radiation promotes fruit ripening and modifies stage-specific anthocyanin metabolism in highbush blueberry显示文摘Ultraviolet-B(UV-B)light(280–315 nm)is an important environmental signal that regulates plant development and photomorphogenesis,while also affecting the flavonoid pathway,including anthocyanin biosynthesis.Regarding the effects of UV-B radiation on fruits,the effects of a short-term or postharvest irradiation on fruit quality have been well-documented,but the effects of a long-term preharvest UV-B irradiation on fruit growth and coloration remain unclear.Thus,in this study,we investigated the effects of a long-term treatment involving an environmentally relevant UV-B dose on highbush blueberry(Vaccinium corymbosum)fruit.The preharvest UV-B treatment quickly promoted fruit growth and sugar accumulation,which is not commonly observed in other fruit tree species.The UV-B exposure also accelerated fruit ripening and coloration.The dual-luciferase assay proved that in blueberries,expression of VcUFGT encoding anthocyanin biosynthesis key enzyme,is positively and negatively regulated by VcMYBA1 and VcMYBC2,respectively.Throughout the fruit development stage,the UV-B treatment up-regulated VcMYBPA1 expression,which increased VcUFGT expression via VcMYBA1.In the green fruit stage,the UV-B treatment increased HY5 encoding UV receptor,which up-regulates VcMYBPA1 and down-regulates VcMYBC2,thereby promotes the accumulation of anthocyanins.On the other hand,excessive anthocyanin synthesis was inhibited by increased VcMYBC2 levels in mature fruits when exposed to UV-B light through HY5-independent pathway.In conclusion,anthocyanin-related MYB activators and repressor may coordinately balance the accumulation of anthocyanins in blueberry fruits,with UV-B treatments possibly influencing their effects in a stage-specific manner.The potential utility of preharvest UV-B treatments for improving blueberry fruit quality is discussed herein. | Taishan Li Hisayo Yamane Ryutaro Tao | 2021 | Horticulture Research2021，8，1： | 6 |
| 2 | Effect of adiponectin on carotid arterial stiffness in type 2 diabetic patients treated with pioglitazone and metformin显示文摘 | Takahiro Araki Masanori Emoto Megumi Teramura Hisayo Yokoyama Katsuhito Mori Sawako Hatsuda Takaaki Maeno Kayo Shinohara Hidenori Koyama Tetsuo Shoji Masaaki Inaba Yoshiki Nishizawa | 2006 | Metabolism2006，，8： | 5 |
| 3 | Apple whole genome sequences:recent advances and new prospects显示文摘In 2010,a major scientific milestone was achieved for tree fruit crops:publication of the first draft whole genome sequence(WGS)for apple(Malus domestica).This WGS,v1.0,was valuable as the initial reference for sequence information,fine mapping,gene discovery,variant discovery,and tool development.A new,high quality apple WGS,GDDH13 v1.1,was released in 2017 and now serves as the reference genome for apple.Over the past decade,these apple WGSs have had an enormous impact on our understanding of apple biological functioning,trait physiology and inheritance,leading to practical applications for improving this highly valued crop.Causal gene identities for phenotypes of fundamental and practical interest can today be discovered much more rapidly.Genome-wide polymorphisms at high genetic resolution are screened efficiently over hundreds to thousands of individuals with new insights into genetic relationships and pedigrees.High-density genetic maps are constructed efficiently and quantitative trait loci for valuable traits are readily associated with positional candidate genes and/or converted into diagnostic tests for breeders.We understand the species,geographical,and genomic origins of domesticated apple more precisely,as well as its relationship to wild relatives.The WGS has turbo-charged application of these classical research steps to crop improvement and drives innovative methods to achieve more durable,environmentally sound,productive,and consumer-desirable apple production.This review includes examples of basic and practical breakthroughs and challenges in using the apple WGSs.Recommendations for“what’s next”focus on necessary upgrades to the genome sequence data pool,as well as for use of the data,to reach new frontiers in genomics-based scientific understanding of apple. | Cameron P.Peace Luca Bianco Michela Troggio Eric van de Weg Nicholas P.Howard Amandine Cornille Charles-Eric Durel Sean Myles ZoëMigicovsky Robert J.Schaffer Evelyne Costes Gennaro Fazio Hisayo Yamane Steve van Nocker Chris Gottschalk Fabrizio Costa David Chagné Xinzhong Zhang Andrea Patocchi Susan E.Gardiner Craig Hardner Satish Kumar Francois Laurens Etienne Bucher Dorrie Main Sook Jung Stijn Vanderzande | 2019 | Horticulture Research2019，6，1： | 3 |
| 4 | The association of plasma adiponectin level with carotid arterial stiffness显示文摘 | Takahiro Araki Masanori Emoto Hisayo Yokoyama Takaaki Maeno Sawako Hatsuda Katsuhito Mori Hidenori Koyama Tetsuo Shoji Masaaki Inaba Yoshiki Nishizawa | 2006 | Metabolism2006，，5： | 2 |
| 5 | Expression of osteopontin and CDX2: Indications of phenotypes and prognosisin advanced gastric cancer显示文摘 | Xia Zhang Tetsuya Tsukamoto Tsutomu Mizoshita Hisayo Ban Hidenori Suzuki Takeshi Toyoda Masae Tatematsu | 2009 | Oncology Reports2009，，3： | 2 |
| 6 | Effect of Aerobic Ex-ercise on Plasma Adiponectin Levels and Insulin Resistance in type 2 diabetes显示文摘 | Masanori E Takahiro A | 2004 | Diabetes Care2004，27，7： | 1 |
| 7 | Ex- pression analysis of PpDAM5 and PpDAM6 during flower bud development in peach (Prunus persica)显示文摘 | Hisayo Yamane Tomomi Ooka Hiroaki Jotatsu | 2011 | Scientia Horti- culturae 2011 b2011，129，： | 1 |
| 8 | Bioremediation ofcadmium contaminated soil using symbiosis betweenleguminous plant and recombinant rhizobia with the MTL4 andthe PCS genes显示文摘 | Akiko I Rutchadapom S Hisayo 0 | 2007 | Chemosphere2007，66，： | 1 |
| 9 | Self-aligned nickel-mono-silicide technology for high-speed deep submicrometer logic CMOS ULSI显示文摘 | Toyota Morimoto Tatsuya Ohguro Hisayo Sasaki Momose | 1995 | IEEE Transactions on Electron Devices1995，42，5： | 1 |
| 10 | Trapidil inhibits platelet-derived growth factor-induced migration via protein kinase A and RhoA/Rho-as-sociated kinase in rat vascular smooth muscle cells显示文摘 | Kenji I Hisayo F Mariko H | 2005 | Eur J Pharma-col2005，515，13： | 1 |
| 11 | Pancreatic duct holder for facilitating duct-to-mucosa pancreatojejunostomy after pancreatoduodenectomy显示文摘 | Masanori Sugiyama Yutaka Suzuki Nobutsugu Abe Hisayo Ueki Tadahiko Masaki Toshiyuki Mori Yutaka Atomi | 2009 | The American Journal of Surgery2009，，1： | 1 |
| 12 | The use of the Shaplotype-specific F-box protein gene, SFB, as a molecular marker for S-haplotypes and self-compatibility in Japanese apricot (Prunus mume)显示文摘 | HISAYO Y KOICHIRO U HIDENORI S RYUTARO T | 2003 | Theor Appl Genet2003，107，： | 1 |
| 13 | Cytoplasmic male sterility-as- sociated ORF79 is toxic to plant regeneration when expressed with mitochondrial targeting sequence of ATPase ~ subunit显示文摘 | Hisayo K Tomohiko K Sota F | 2010 | Plant Bio- technology2010，27，： | 1 |
| 14 | Dual roles of CagA protein in Helicobacter pylori -induced chronic gastritis in mice显示文摘 | Masahiro Kido Norihiko Watanabe Nobuhiro Aoki Satoru Iwamoto Hisayo Nishiura Ryutaro Maruoka Aki Ikeda Takeshi Azuma Tsutomu Chiba | 2011 | Biochemical and Biophysical Research Communications2011，，2： | 1 |
| 15 | Structure and expression of human fibroblast growth factor-10 显示文摘 | Shuzo T Marie-Geneviève M | 1997 | J Biol Chem1997，272，23： | 1 |
| 16 | Promotion of metal accumulation in nodule of Astragalus sinicus by the expression of the Iron-regulated Transporter Gene in Mesorhizobium huakuii subsp, rengei B3显示文摘 | AKIKO IKE RUTCHADAPORN SPIPRANG HISAYO ONO | 2008 | Journal of bioscience and bioengineering The Society for Biotechnology Japan2008，105，6： | 1 |
| 17 | Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolicacid in Prunus mume Sieb. et Zucc.显示文摘 | Ko-ichi Kawahara Teruto Hashiguchi Kazuo Masuda Abbi Saniabadi Kiyoshi Kikuchi Salunya Tancharoen Takashi Ito Naoki Miura Yoko Morimoto Kamal Biswas Yuko Nawa Xiaojie Meng Yoko Oyama Kazunori Takenouchi Binita Shrestha Hisayo Sameshima Toshiaki Shimizu Ta | 2009 | International Journal of Molecular Medicine2009，，5： | 1 |
| 18 | Effect of protein and energy intakes on body composition in non- diabetic mainteinance- hemodialysis patients显示文摘 | Yoka Ichikawa Fumie Hiramatsu Hisayo Hamada | 2007 | J NutrSciVitaminol2007，53，： | 1 |
| 19 | Targeted disruption of an orthologue of DOMAINS REARRANGED METHYLASE?2, OsDRM2 , impairs the growth of rice plants by abnormal DNA methylation显示文摘 | Satoru Moritoh Chang‐Ho Eun Akemi Ono Hisayo Asao Yosuke Okano Katsushi Yamaguchi Zenpei Shimatani Amane Koizumi Rie Terada | 2012 | The Plant Journal2012，，1： | 1 |
| 20 | The association of plasma adiponectin level with carotid arterial stiffness显示文摘 | Takahiro Araki Masanori Emoto Hisayo Yokoyama Takaaki Maeno Sawako Hatsuda Katsuhito Mori Hidenori Koyama Tetsuo Shoji Masaaki Inaba Yoshiki Nishizawa | 2006 | Metabolism2006，，5： | 1 |
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