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| 1 | Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair显示文摘In the field of bone defect repair,3D printed scaffolds have the characteristics of personalized customization and accurate internal structure.However,how to construct a well-structured vascular network quickly and effectively inside the scaffold is essential for bone repair after transplantation.Herein,inspired by the unique biological structure of“lotus seedpod”,hydrogel microspheres encapsulating deferoxamine(DFO)liposomes were prepared through microfluidic technology as“lotus seeds”,and skillfully combined with a three-dimensional(3D)printed bioceramic scaffold with biomimetic“lotus”biological structure which can internally grow blood vessels.In this composite scaffold system,DFO was effectively released by 36%in the first 6 h,which was conducive to promote the growth of blood vessels inside the scaffold quickly.In the following 7 days,the release rate of DFO reached 69%,which was fundamental in the formation of blood vessels inside the scaffold as well as osteogenic differentiation of bone mesenchymal stem cells(BMSCs).It was confirmed that the composite scaffold could significantly promote the human umbilical vein endothelial cells(HUVECs)to form the vascular morphology within 6 h in vitro.In vivo,the composite scaffold increased the expression of vascularization and osteogenic related proteins Hif1-α,CD31,OPN,and OCN in the rat femoral defect model,significantly cutting down the time of bone repair.To sum up,this“lotus seedpod”inspired porous bioceramic 3D printed scaffold with internal vascularization functionality has broad application prospects in the future. | Xiaoyu Han Mingjie Sun Bo Chen Qimanguli Saiding Junyue Zhang Hongliang Song Lianfu Deng Peng Wang Weiming Gong Wenguo Cui | 2021 | Bioactive Materials2021，6，6： | 4 |
| 2 | InP based DFB laser array integrated with MMI coupler显示文摘The techniques used for the fabrication of photonic integrated circuit(PIC) chip are introduced briefly.Then a four channel DFB laser array integrated with MMI coupler and semiconductor optical amplifier(SOA) fabricated with butt-joint technique,varied ridge width and holographic exposure techniques is reported. | ZHU HongLiang MA Li LIANG Song ZHANG Can WANG BaoJun ZHAO LingJuan WANG Wei | 2013 | Chinese Science Bulletin2013，58，7： | 3 |
| 3 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 4 | A selective area growth double stack active layer electroabsorption modulator integrated with a distributed feedback laser显示文摘A new method for fabricating electroabsorption modulator integrated with a distributed feedback laser(EML) was proposed.With the method we fabricated a selective area growth double stack active layer EML(SAG-DSAL-EML).Through comparing with other fabrication methods of EMLs,the characters and the merits of the new method presented in this paper were discussed. | ZHU HongLiang LIANG Song ZHAO Ling Juan KONG DuanHua ZHU NingHua WANG Wei | 2009 | Chinese Science Bulletin2009，54，20： | 3 |
| 5 | Preparation of high selectivity silicalite-1 membranes by two-step in situ hydrothermal synthesis显示文摘High selectivity silicalite-1 membranes were synthesized on silica tubes by in situ hydrothermal synthesis. Using a two-step synthesis, a membrane with a separation factor of 99 was prepared for separating an ethanol/water mixture at 60°C. The average (n = 4) flux and separation factor of the membranes were 0.47 kg m-2 h-1 and 89, respectively. The membranes exhibited high reproducibility, and the relative standard deviation of the average (n = 4) flux and separation factor were only 5.3% and 9.2%, respectively. These results suggest that silica is a suitable support for synthesis of high-performance silicalite-1 membranes. | CHEN HongLiang LI YanShuo YANG JiSong HOU YongXia SONG XueYing HU XiaoJun YANG WeiShen | 2011 | Chinese Science Bulletin2011，56，33： | 2 |
| 6 | Preparation of CoP films by ultrasonic electroless deposition at low initial temperature显示文摘Electroless deposition technology has been considered as a kind of common ways to obtain cobalt alloy films. However, in order to get cobalt alloy films, high temperature(353 K) is necessary during the electroless deposition process which will increase costs and energy consumption. Ultrasonic was introduced during electroless plating process to obtain cobalt alloy films at lower initial temperature. It was found that the cobalt thin films could be prepared at lower initial temperature(323 K) with the introduction of ultrasonic. Therefore, different powers of ultrasonic were applied during the electroless deposition process to prepare CoP thin films on copper substrates from an alkaline bath in this investigation. The effects of different powers of ultrasonic on deposition rate, surface morphology, anticorrosion performance and magnetic property of films were studied. It was found that the deposition rate increased gradually with the rise in ultrasonic powers due to cavitation phenomenon. All the CoP films presented the typical spherical nodular structures with the impact of ultrasonic. Smaller and regular shaped structures could be observed when the films were deposited with higher power of ultrasonic which contributed directly to enhancement of anticorrosion performance. Saturation magnetization and coercivity of thin films increased gradually with the rise in ultrasonic powers during the electroless deposition process due to the higher amounts of cobalt.& 2014 Chinese Materials Research Society. Production and hosting by Elsevier B.V. All rights reserved. | Yundan Yu Zhenlun Song Hongliang Ge Guoying Wei | 2014 | Progress in Natural Science:Materials International2014，24，3： | 2 |
| 7 | High-metallic-phase-concentration MO1-xWxS2 nanosheets with expanded interlayers as efficient electrocatalysts显示文摘 | Qun He Yangyang Wan Hongliang Jiang Chuanqiang Wu Zhongti Sun Shuangming Chen Yu Zhou Haiping Chen Daobin Liu Yasir A. Haleem Binghui Ge Xiaojun Wu Li Song | 2018 | Nano Research2018，11，3： | 1 |
| 8 | Dye-sensitized solar cells based on anatase TiO 2 /multi-walled carbon nanotubes composite nanofibers photoanode显示文摘 | Pingfan Du Lixin Song Jie Xiong Ni Li Lijun Wang Zhenqiang Xi Naiyan Wang Linhui Gao Hongliang Zhu | 2013 | Electrochimica Acta2013，，： | 1 |
| 9 | Determination of tetracycline in milk by using nucleotide/lanthanide coordination polymer-based ternary complex显示文摘 | Hongliang Tan Chanjiao Ma Yonghai Song Fugang Xu Shouhui Chen Li Wang | 2013 | Biosensors and Bioelectronics2013，，： | 1 |
| 10 | Wave LBP based hier- archical features for image classification显示文摘 | Song Tiecheng Li Hongliang | 2013 | Pattern Recognition Letters2013，34，： | 1 |
| 11 | Efficient fabrication and photocatalytic properties of TiO 2 hollow spheres显示文摘 | Chunyan Song Wujiang Yu Bin Zhao Hongliang Zhang Changjin Tang Keqin Sun Xingcai Wu Lin Dong Yi Chen | 2008 | Catalysis Communications2008，，： | 1 |
| 12 | Determination of tetracycline in milk by using nucleotide/lanthanide coordination polymer-based ternary complex显示文摘 | Hongliang Tan Chanjiao Ma Yonghai Song Fugang Xu Shouhui Chen Li Wang | 2013 | Biosensors and Bioelectronics2013，，： | 1 |
| 13 | Obser- vations and Mechanistic Insights on Unusual Stability of Neu- tral Nickel Complexes with a Sterically Crowded Metal Center 显示文摘 | Song Dongpo Wang Yongxia Mu Hongliang | 2011 | Organometallics2011，30，5： | 1 |
| 14 | Grain refining efficiency and microstructure of Al–Ti–C–RE master alloy显示文摘 | Hongliang Zhao Yong Song Miao Li Shaokang Guan | 2010 | Journal of Alloys and Compounds2010，，1： | 1 |
| 15 | Relationship of serum GDF11 levels with bone mineral density and bone turnover markers in postmenopausal Chinese women显示文摘Growth differentiation factor 11(GDF11) is an important circulating factor that regulates aging.However,the role of GDF11 in bone metabolism remains unclear.The present study was undertaken to investigate the relationship between serum GDF11 level,bone mass,and bone turnover markers in postmenopausal Chinese women.Serum GDF11 level,bone turnover biochemical markers,and bone mineral density(BMD) were determined in 169 postmenopausal Chinese women(47–78 years old).GDF11 serum levels increased with aging.There were negative correlations between GDF11 and BMD at the various skeletal sites.After adjusting for age and body mass index(BMI),the correlations remained statistically significant.In the multiple linear stepwise regression analysis,age or years since menopause,BMI,GDF11,and estradiol were independent predictors of BMD.A significant negative correlation between GDF11 and bone alkaline phosphatase(BAP) was identified and remained significant after adjusting for age and BMI.No significant correlation was noted between cross-linked N-telopeptides of type I collagen(NTX) and GDF11.In conclusion,GDF11 is an independent negative predictor of BMD and correlates with a biomarker of bone formation,BAP,in postmenopausal Chinese women.GDF11 potentially exerts a negative effect on bone mass by regulating bone formation. | Yusi Chen Qi Guo Min Zhang Shumin Song Tonggui Quan Tiepeng Zhao Hongliang Li Lijuan Guo Tiejian Jiang Guangwei Wang | 2016 | Bone Research2016，4，1： | 1 |
| 16 | The First High-quality Reference Genome of Sika Deer Provides Insights into High-tannin Adaptation显示文摘Sika deer are known to prefer oak leaves,which are rich in tannins and toxic to most mammals;however,the genetic mechanisms underlying their unique ability to adapt to living in the jungle are still unclear.In identifying the mechanism responsible for the tolerance of a highly toxic diet,we have made a major advancement by explaining the genome of sika deer.We generated the first high-quality,chromosome-level genome assembly of sika deer and measured the correlation between tannin intake and RNA expression in 15 tissues through 180 experiments.Comparative genome analyses showed that the UGT and CYP gene families are functionally involved in the adaptation of sika deer to high-tannin food,especially the expansion of the UGT family 2 subfamily B of UGT genes.The first chromosome-level assembly and genetic characterization of the tolerance to a highly toxic diet suggest that the sika deer genome may serve as an essential resource for understanding evolutionary events and tannin adaptation.Our study provides a paradigm of comparative expressive genomics that can be applied to the study of unique biological features in non-model animals. | Xiumei Xing Cheng Ai Tianjiao Wang Yang Li Huitao Liu Pengfei Hu Guiwu Wang Huamiao Liu Hongliang Wang Ranran Zhang Junjun Zheng Xiaobo Wang Lei Wang Yuxiao Chang Qian Qian Jinghua Yu Lixin Tang Shigang Wu Xiujuan Shao Alun Li Peng Cui Wei Zhan Sheng Zhao Zhichao Wu Xiqun Shao Yimeng Dong Min Rong Yihong Tan Xuezhe Cui Shuzhuo Chang Xingchao Song Tongao Yang Limin Sun Yan Ju Pei Zhao Huanhuan Fan Ying Liu Xinhui Wang Wanyun Yang Min Yang Tao Wei Shanshan Song Jiaping Xu Zhigang Yue Qiqi Liang Chunyi Li Jue Ruan Fuhe Yang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 1 |
| 17 | Legendre Neural Network for Solving Linear Variable Coefficients Delay Differential-Algebraic Equations with Weak Discontinuities显示文摘In this paper,we propose a novel Legendre neural network combined with the extreme learning machine algorithm to solve variable coefficients linear delay differential-algebraic equations with weak discontinuities.First,the solution interval is divided into multiple subintervals by weak discontinuity points.Then,Legendre neural network is used to eliminate the hidden layer by expanding the input pattern using Legendre polynomials on each subinterval.Finally,the parameters of the neural network are obtained by training with the extreme learning machine.The numerical examples show that the proposed method can effectively deal with the difficulty of numerical simulation caused by the discontinuities. | Hongliang Liu Jingwen Song Huini Liu Jie Xu Lijuan Li | 2021 | Advances in Applied Mathematics and Mechanics2021，13，1： | 1 |
| 18 | Highly Enantioselective Intramolecular Morita-Baylis-Hillman Reaction Catalyzed by Mannose-Based Thiourea-phosphine显示文摘基于糖类的 chiral bifunctional thiourea 磷化氢为 ω-formyl-enones 的 intramolecular Morita-Baylis-Hillman 反应作为 chiral organocatalysts 被开发。与仅仅 thiourea 磷化氢催化剂 3c 的 2 mol% , chiral functionalized cyclohexenes 与优秀收益和 enantioselectivities 在温和反应条件下面被完成。 | Weihong Yang Kui Yuan Hongliang Song Feng Sha Xinyan Wu | 2015 | Chinese Journal of Chemistry2015，33，10： | 1 |
| 19 | Lanthanide-functionalized silver nanoparticles for detection of an anthrax biomarker and test paper fabrication显示文摘 | Hongliang Tan Qian Li Chanjiao Ma Yonghai Song Fugang Xu Shouhui Chen Li Wang | 2014 | Journal of Nanoparticle Research2014，，1： | 1 |
| 20 | Combined Size and Shape Optimization of Structures with DOE,RSM and GA显示文摘In this paper,size and shape optimization problem of a machine gun system is addressed with an efficient hybrid method,in which a novel and flexible mesh morphing technique is employed to achieve fast parameterization and modification of complexity structure without going back to CAD for reconstruction of geometric models or to finite element analysis( FEA) for remodeling. Design of experiments( DOE) and response surface method( RSM) are applied to approximate the constitutive parameters of a machine gun system based on experimental tests. Further FEA,secondary development technique and genetic algorithm( GA) are introduced to find all the optimal solutions in one go and the optimal design of the demonstrated machine gun system is obtained. Results of the rigid-flexible coupling dynamic analysis and exterior ballistics calculation validate the proposed methodology,which is relatively time-saving,reliable and has the potential to solve similar problems. | Jie Song Hongliang Hua Zhenqiang Liao Tao Wang Ming Qiu | 2018 | Journal of Beijing Institute of Technology2018，27，2： | 1 |
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