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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018,63,23: | 54 |
| 2 | Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China:A multicenter retrospective study显示文摘Importance:The clinical characteristics of infectious mononucleosis(IM)in Chinese children have not been evaluated in multicenter studies,and the effectiveness of antiviral treatment are controversial.Objective:To investigate the clinical characteristics of Chinese children with IM and current status of antiviral therapy for affected patients.Methods:Hospitalized patients with IM were enrolled between 2018 and 2020 in five children’s hospitals in China.The clinical characteristics were compared among four age groups:<3 years,3-<6 years,6-<10 years,and≥10 years.The clinical characteristics of IM and effectiveness of antiviral therapy were compared among patients receiving acyclovir(ACV),ganciclovir(GCV),and no antiviral therapy(i.e.,non-antiviral group).Results:In total,499 patients were analyzed;most patients were 3-<6 years of age.The most common symptoms and signs included fever(100%),lymphadenopathy(98.6%),pharyngitis(86.4%),eyelid edema(76.8%),and snoring(72.9%).There were significant differences in rash,hepatomegaly,and liver dysfunction among the four age groups.Patients aged<3 years had a lower incidence of liver dysfunction and a higher incidence of rash.Among the 499 patients,50.1%were treated with GCV,26.3%were treated with ACV,and 23.6%received no antiviral therapy.Compared with the non-antiviral group,patients in the ACV and GCV groups had longer durations of fever(P<0.001).There were no significant differences in the incidences of complications among the three treatment groups.Interpretation:The incidence of IM in Chinese children peaked at 3-<6 years of age.Clinical features of IM varied according to age.Patients receiving antiviral therapy exhibited more serious clinical manifestations than did patients without antiviral therapy.The effectiveness of antiviral therapy for IM requires further analysis. | Huili Hu Huiling Deng Jing Bi Yi Xu Shuangjie Li Yue Xie Xinrong Sun Dongmeng Wang Xufang Li Wenxian Ouyang Bing Hu Yufeng Zhang He Tang Chunxiao Fang Hui Zhang Lingyun Guo Chen Wang Tianyi Wang Fengxia Yang Tao Jiang Zhengde Xie Gang Liu | 2021 | Pediatric Investigation2021,5,3: | 12 |
| 3 | Assessing the impact of fungicide enostroburin application on bacterial community in wheat phyllosphere显示文摘Fungicides have been used extensively for controlling fungal pathogens of plants. However, little is known regarding the effects that fungicides upon the indigenous bacterial communities within the plant phyllosphere. The aims of this study were to assess the impact of fungicide enostroburin upon bacterial communities in wheat phyllosphere. Culture-independent methodologies of 16S rDNA clone library and 16S rDNA directed polymerase chain reaction with denaturing gradient gel electrophoresis (PCR-DGGE) were used for monitoring the change of bacterial community. The 16S rDNA clone library and PCR-DGGE analysis both confirmed the microbial community of wheat plant phyllosphere were predominantly of the γ-Proteobacteria phyla. Results from PCR-DGGE analysis indicated a significant change in bacterial community structure within the phyllosphere following fungicide enostroburin application. Bands sequenced within control cultures were predominantly of Pseudomonas genus, but those bands sequenced in the treated samples were predominantly strains of Pantoea genus and Pseudomonas genus. Of interest was the appearance of two DGGE bands following fungicide treatment, one of which had sequence similarities (98%) to Pantoea sp. which might be a competitor of plant pathogens. This study revealed the wheat phyllosphere bacterial community composition and a shift in the bacterial community following fungicide enostroburin application. | Likun Gu Zhihui Bai Bo Jin Qing Hu Huili Wang Guoqiang Zhuang HongxunZhang | 2010 | Journal of Environmental Sciences2010,22,1: | 6 |
| 4 | Study on falling film generation heat transfer of lithium bromide solution in vertical tubes显示文摘Falling film generation process in lithium bromide absorption refrigeration generation system is researched in thispaper. To describe the coupled heat and mass transfer of laminar falling film in vertical generation tube, a mathematicalmodel is developed, in which the effect of mass transfer on heat transfer is carefully evaluated. Moreover,an equation related Re number with solution volume flow was also obtained in given conditions. We carried outthe experiments with the mass fraction of the inlet solution LiBr being 49.5% and obtained an empirical correlationof heat transfer with the film Re number and heat flux in different volume flow. Specifically, when 5kW/m2 | Chengming Shi Canjun Xu Huili Hu Yang YingDepartment of Power Engineering, Chongqing University, 400044, Chongqing, China, | 2009 | Journal of Thermal Science2009,18,3: | 5 |
| 5 | The Effect of Home-Based Cardiac Rehabilitation on Functional Capacity,Behavior,and Risk Factors in Patients with Acute Coronary Syndrome in China显示文摘Aim:To investigate the effect of home-based cardiac rehabilitation on functional capacity,health behavior,and risk factors in patients with acute coronary syndrome in China.Methods:Eighty patients with acute coronary syndrome were enrolled in this prospective randomized controlled study.Patients in the cardiac rehabilitation group(n=52)received home-based cardiac rehabilitation with a heart manual and a home exercise video for 3 months and patients in the control group(n=28)received only routine secondary prevention.The 6-min walk distance,laboratory test results,healthy behavior(questionnaire),quality of life(12-item Short Form Health Survey),anxiety(7-item Generalized Anxiety Disorder Questionnaire),and depression(9-item Patient Health Questionnaire)were evaluated at the beginning and after treatment for 3 months.Results:Compared with baseline data,52 patients who participated in cardiac rehabilitation had longer 6-min walk distance(515.26±113.74 m vs 0.445.30±97.92 m,P<0.0002),higher proportions of“always exercise”(78.26% vs.28%,P<0.05),“always limit food with sugar”(65.22% vs 12%,P<0.05),“always eat fruits 200–400 g every day”(82.61% vs.4%,P<0.05).and“always eat vegetables 300–500 g every day”(21.74%vs.12%,P<0.06)after treatment for 3 months.The low-density lipoprotein cholesterol control rate(52.17% vs.28%,P<0.05)and the systolic blood pressure control rate(100%vs.68%,P<0.05)were also signifi cantly increased after treatment for 3 months in the cardiac rehabilitation group.No signifi cant increase was found in the control group after treatment for 3 months.No cardiac-event related to home exercise was reported in both groups.Conclusion:Home-based cardiac rehabilitation is a feasible and available cardiac rehabilitation mode in China. | Rongjing Ding Jianchao Li Limin Gao Liang Zhu Wenli Xie Xiaorong Wang Qin Tang Huili Wang Dayi Hu | 2017 | Cardiovascular Innovations and Applications2017,,B02: | 5 |
| 6 | Single-cell RNA sequencing of meiocytes and microspores reveals the involvement of the Rf4 gene in redox homeostasis of CMS-C maize显示文摘Normal microsporogenesis is determined by both nuclear and mitochondrial genes. In maize C-type cytoplasmic male sterility, it is unclear how the development of meiocytes and microspores is affected by the mitochondrial sterility gene and the nuclear restorer gene. In this study, we sequenced the transcriptomes of single meiocytes(tetrad stage) and early mononucleate microspores from sterile and restorer lines. The numbers of expressed genes varied in individual cells and fewer than half of the expressed genes were common to the same cell types. Four comparisons revealed 3379 differentially expressed genes(DEGs), with 277 putatively associated with mitochondria, 226 encoding transcription factors,and 467 possibly targeted by RF4. KEGG analysis indicated that the DEGs in the two lines at the tetrad stage were involved predominantly in carbon metabolism and in amino acid biosynthesis and metabolism, whereas the DEGs during the transition from the tetrad stage to the early mononucleate stage were associated mostly with regulation of protein metabolism, fatty acid metabolism, and anatomical structure morphogenesis. Thus, meiocyte and microspore development was affected by the surrounding cells and the restorer gene, and the restorer gene helped restore the redox homeostasis of microspores and the normal cellular reconstruction during the transition. | Huaisheng Zhang Huili Yang Desheng Hu Bing Li Yanan Lin Wen Yao Zhanyong Guo Haochuan Li Dong Ding Zhanhui Zhang Yanmin Hu Yadong Xue Jihua Tang | 2021 | The Crop Journal2021,9,6: | 4 |
| 7 | Silk materials for medical, electronic and optical applications显示文摘Silk derived from the silkworm Bombyx mori is among the most important fibrous protein biomaterials due to large-scale production from natural sources, excellent biocompatibility, unique mechanical properties and controllable degradation. Silk fibroin can be processed into a variety of formats to match different applications, such as tissue engineering, drug delivery or as the passive substrate of a bio-device. Advances in fabrication technologies provide new possibilities for the combination of silk fibroin with other nanomaterials to functionalize silk fibroin for specialized purposes, including sensing, cell visualization,resistance to ultraviolet light and provision of antibacterial properties. As the requirement for wearable and intelligent devices has become increasingly important over recent years, silk fibroin has been utilized as the active element in electronic and optical instruments. This review summarizes these recent advances in the innovative applications of silk fibroin. | FAN SuNa ZHANG Yi HUANG XiangYu GENG LiHong SHAO HuiLi HU XueChao ZHANG YaoPeng | 2019 | Science China(Technological Sciences)2019,62,6: | 4 |
| 8 | Mathematical Simulation of Lithium Bromide Solution Laminar Falling Film Evaporation in Vertical Tube显示文摘For utilization of the residual heat of flue gas to drive the absorption chillers,a lithium-bromide falling film in vertical tube type generator is presented.A mathematical model was developed to simulate the heat and mass coupled problem of laminar falling film evaporation in vertical tube.In the model,the factor of mass transfer was taken into account in heat transfer performance calculation.The temperature and concentration fields were calculated.Some tests were conducted for the factors such as Re number,heating flux,the inlet concentration and operating pressure which can affect the heat and mass transfer performance in laminar falling film evaporation.The heat transfer performance is enhanced with the increasing of heat flux.An increasing inlet concentration can weaken the heat transfer performance.The operating pressure hardly affects on heat and mass transfer.The bigger inlet Re number means weaker heat transfer effects and stronger mass transfer.The mass transfer obviously restrains the heat transfer in the falling film solution.The relation between dimensionless heat transfer coefficient and the inlet Re number is obtained. | Chengming Shi YangWang Huili Hu YingYang | 2010 | Journal of Thermal Science2010,19,3: | 3 |
| 9 | Role of humidity on the structures and properties of regenerated silk fibers显示文摘Silk fiber was processed from highly concentrated spinning dope to solid fibers along with water removal. To understand the mechanism of water removal during silk fiber spinning process, a microfluidic chip was designed and applied to investigate the structures and mechanical properties of two kinds of regenerated silk fibroin fibers dry-spun at different relative humidity. The experimental results showed that the diameters of the fibers spun at 40% RH are always larger than the fibers spun at 50% RH due to different removal rates of water. The fibers spun at low humidity contain more β-sheet structure and lower degree of chain orientation and crystalline orientation. These results indicate that the fast phase transition of silk fibroin from sol–gel to silk fiber undergoes with rapid water removal and higher fiber orientation relates to more residue water and drawing force. | Qingfa Peng Huili Shao Xuechao Hu Yaopeng Zhang | 2015 | Progress in Natural Science:Materials International2015,25,5: | 3 |
| 10 | Experimental studies of biomass gasification with air显示文摘In this work,experimental studies of biomass gasification under different operating conditions were carried out in an updraft gasifier combined with a copper slag reformer.The influence of gasification temperature,equivalence ratio(ER) and copper slag catalyst addition on gas production and tar yield were investigated.The experimental results showed that the content of H2 and CO,gas yield and LHV increased,while the tar yield and the content of CO2,CH4 and C2Hx in the gas product decreased with the temperature.At 800C,with the increase of ER,the LHV,the tar yield and the content of H2,CO,CH4 and C2Hx in gas products decreased,while the gas yield and the content of CO2 increased.Copper slag was introduced into the secondary reformer for tar decomposition.The Fe3O4 phase in the fresh copper slag was reduced to FeO(Fe2+) and metallic Fe by the gas product.Fe species(FeO and metallic Fe) acted as the active sites for tar catalytic decomposition.The catalytic temperature had a significant influence on tar conversion and the composition of the gas product.Typically,the tar conversion of about 17%-54% could be achieved when the catalytic temperature was varied from 750 to 950 C.Also,the content of H2 and CO increased with the catalytic temperature,while that of CO2,CH4 and C2Hx in the gas product decreased.It was demonstrated that copper slag was a good catalyst for upgrading the gas product from biomass gasification. | Huili Liu Jianhang Hu Hua Wang Chao Wang Juanqin Li | 2012 | Journal of Natural Gas Chemistry2012,21,4: | 2 |
| 11 | CUL4B facilitates HBV replication by promoting HBx stabilization显示文摘Objective:Hepatitis B virus(HBV)infection is a major public health problem worldwide.However,the regulatory mechanisms underlying HBV replication remain unclear.Cullin 4 B-RING ubiquitin E3 ligase(CRL4 B)is involved in regulating diverse physiological and pathophysiological processes.In our study,we aimed to explain the role of CUL4 B in HBV infection.Methods:Cul4 b transgenic mice or conditional knockout mice,as well as liver cell lines with CUL4 B overexpression or knockdown,were used to assess the role of CUL4 B in HBV replication.Immunoprecipitation assays and immunofluorescence staining were performed to study the interaction between CUL4 B and HBx.Cycloheximide chase assays and in vivo ubiquitination assays were performed to evaluate the half-life and the ubiquitination status of HBx.Results:The hydrodynamics-based hepatitis B model in Cul4 b transgenic or conditional knockout mice indicated that CUL4 B promoted HBV replication(P<0.05).Moreover,the overexpression or knockdown system in human liver cell lines validated that CUL4 B increased HBV replication in an HBx-dependent manner.Importantly,immunoprecipitation assays and immunofluorescence staining showed an interaction between CUL4 B and HBx.Furthermore,CUL4 B upregulated HBx protein levels by inhibiting HBx ubiquitination and proteasomal degradation(P<0.05).Finally,a positive correlation between CUL4 B expression and HBV pg RNA level was observed in liver tissues from HBV-positive patients and HBV transgenic mice.Conclusions:CUL4 B enhances HBV replication by interacting with HBx and disrupting its ubiquitin-dependent proteasomal degradation.CUL4 B may therefore be a potential target for anti-HBV therapy. | Haixia Shan Bo Wang Xiaodong Zhang Hui Song Xi Li Yongxin Zou Baichun Jiang Huili Hu Hao Dou Changshun Shao Lifen Gao Chunhong Ma Xiaoyun Yang Xiaohong Liang Yaoqin Gong | 2022 | Cancer Biology & Medicine2022,19,1: | 2 |
| 12 | Lyocell fibers as the precursor of carbon fiber显示文摘 | Peng Shunjin Shao Huili Hu Xuechao | 2003 | Journal of Applied Polymer Science2003,90,7: | 1 |
| 13 | Corrosion behavior of chromium-free dacromet coating in seawater显示文摘 | Huili Hu Ning Li Jinning Cheng Lijiao Chen | 2008 | Journal of Alloys and Compounds2008,,1: | 1 |
| 14 | Identification of Inonotus obliquus and Analysis of Antioxidation and Antitumor Activities of Polysaccharides显示文摘 | Yana Song Jing Hui Wei Kou Ru Xin Fei Jia Ning Wang Fengqing Hu Huili Zhang Hongsheng Liu | 2008 | Current Microbiology2008,,5: | 1 |
| 15 | Studies on spinning and rheological behaviors of regenerated silk fibroin/N-methylmorpholine-N-oxide·H2O solutions显示文摘 | Ying Xu Huili Shao Yaopeng Zhang Xuechao Hu | 2005 | Journal of Materials Science2005,,20: | 1 |
| 16 | Corrosion behavior of chromium-free dacromet coating in seawater显示文摘 | Huili Hu Ning Li Jinning Cheng Lijiao Chen | 2008 | Journal of Alloys and Compounds2008,,1: | 1 |
| 17 | Robust Decentralized Control for Uncertain Interconnected Systems with Time- Varying Delays显示文摘 | Heli Hu Huili feng Zhaode Xu | 2004 | Proceedings of the fifth world congress on Intelligent Control and Automation2004,,2: | 1 |
| 18 | Versatile synthesis strategy for carboxylic acid-functionalized upconverting nanophosphors as biological labels显示文摘 | Chen Zhigang Chen Huili Hu he | 2008 | J Am Chem Soc2008,130,10: | 1 |
| 19 | Versatile synthe- sis strategy for carboxylic aeid-functionalized upconverting nanophophors as biological labels 显示文摘 | Chen Zhigang Chen Huili Hu He | 2008 | JACS Articles2008,130,: | 1 |
| 20 | Tough silk fibers prepared in air using a biomimetic microfluidic chip显示文摘 | Jie Luo Lele Zhang Qingfa Peng Mengjie Sun Yaopeng Zhang Huili Shao Xuechao Hu | 2014 | International Journal of Biological Macromolecules2014,,: | 1 |