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| 1 | Design and experimental study of a practical Osculating Inward Cone Waverider Inlet显示文摘A design method based on tip to tail streamline tracing and osculating inward cone methods is discussed for designing the integrated Osculating Inward Cone Waverider Inlet(OICWI). A practical geometrical constrained experimental model of OICWI is designed based on the validated design method. It has a total contraction ratio of 4.61 and inner contraction ratio is 2.0. Wind-tunnel tests have been conducted for the OICWI model at free stream Mach number(Ma_∞) of 4.0, 3.5 and 3.0 respectively. The experimental results show that the OICWI has high flow capture ratio and compression abilities. It can self-start at Ma_∞= 3.5 and 4.0 and its flow capture ratio is 0.73 at Ma_∞= 4.0, and Angle of Attack(AOA) 0°. The research results show that the OICWI has advantages of inward cone waverider and streamline tracing inlet. Present OICWI is a novel approach for waverider inlet integration studies and it will promote the use of waverider inlet integration configuration in the studies of airbreathing hypersonic vehicles. | He Xuzhao Zhou Zheng Qin Si Wei Feng Le Jialing | 2016 | Chinese Journal of Aeronautics2016，29，6： | 8 |
| 2 | Impacts of Large-scale Wind Power Grid Integration on Relay Protection and Countermeasures显示文摘Several large-scale wind turbine tripping accidents occurred in Jiuquan wind power base in 2011.According to the on-site survey and analysis of these accidents related to relay protection,causes were found to be the collection system defects and low correct operation rate of small current grounded line selectors of the unearthed neutral point collection system.By referring to both the characteristics of Jiuquan wind power base and arrangement of relay protection,the short-circuit features of wind power and its impacts on relay protection are analyzed.The collection system and the retrofit of the small current grounded line selector are improved by specific countermeasures.Finally,further research subjects are put forward. | He, Shien Suonan, Jiale Kang, Xiaoning Song, Guobing | 2012 | 电力系统自动化2012，36，8： | 6 |
| 3 | Impact of damping on high speed 850 nm VCSEL performance显示文摘High speed VCSELs are important optical devices in short-reach optical communication links and interconnects because of their low cost and high modulation speeds. In this paper, the impact of damping on the their static and dynamic characteristics is analyzed and demonstrated. Through the shallow corrosion of the top layer DBR, the VCSELs with different damping is designed and fabricated. With the increase of the surface etch depth from 0 to ~55 nm for 9 μm oxide-aperture VCSEL, the K factor related with the damping is reduced from0.31 to 0.23 ns^(-1). When the etch depth of the VCSEL with 9 μm oxide-aperture is decreased to ~25 nm,output power is increased from 4.03 to 4.70 mW and small signal modulation bandwidth is also increased from15.46 to 16.37 GHz. It shows that there is a tradeoff between damping and differential gain for improving modulation speed. | Shuai Hu Xiaoying He Yan He Jiale Su Chong Li Anqi Hu Xia Guo | 2018 | Journal of Semiconductors2018，39，11： | 2 |
| 4 | Voxel-based Shape Analysis and Search of Mechanical CAD-Models显示文摘 | WANG Jiale HE Yuanjun TIAN Haishan | 2007 | Forschung im Ingenieurwesen2007，71，4： | 1 |
| 5 | Voxel-based shape analysis and search of mechanical CAD-models显示文摘 | WANG Jiale HE Yuanjun TIAN Haishan | 2007 | Forschung im Ingenieurwesen2007，71，34： | 1 |
| 6 | Cocaine induces apoptosis in fetal myocardial cells through a mitochondria-dependent pathway显示文摘 | Yuhui Xiao Jiale He Gilbert R D | 1999 | J Pharmacol Exp Ther1999，292，： | 1 |
| 7 | Characterization of a novel regulatory pathway for mannitol metabolism and its coordination with biofilm formation in Mycobacterium smegmatis显示文摘Biofilm formation has been implicated to be tightly regulated in bacteria. Mycobacterial species possess a unique cell-wall structure; however, the underlying regulation mechanism for their biofilm formation remains largely unclear. In this study, we characterized a hypothetical mannitol metabolism and transportation gene cluster(Ms5571-Ms5576), designated as mmt operon, whose expression significantly contributes to the biofilm formation in Mycobacterium smegmatis. We showed that in the operon the Ms5575 gene encodes a GntR-like transcriptional repressor and the Ms5576 gene encodes a mannitol2-dehydrogenase which can produce D-mannitol from D-mannose. Strikingly, the D-mannitol molecule can derepress the negative regulation of Ms5575 on the mmt operon to stimulate the operon's expression. Consistently, addition of D-mannitol into the medium can obviously induce mycobacterial biofilm formation. Furthermore, we found that Ms0179 positively regulates the mmt operon through its downstream regulator Ms0180. Ms0180 directly binds the mmt operon to positively regulate its expression. Both Ms0179 and Ms0180 significantly affect the mycobacterial biofilm formation. Taken together, we explored a regulatory pathway for the mannitol metabolism and its coordination with the biofilm formation in M. smegmatis. This finding provides novel insights into the unique mechanism of biofilm formation regulation in mycobacteria. | Jialing Hu Hua Zhang Si Zhou Weihui Li Zheng-Guo He | 2018 | Journal of Genetics and Genomics2018，45，9： | 1 |
| 8 | Biochar pyrolyzed at low temperature enhanced acidophilous plant growth by promoting rhizospheric microbes in a slightly alkaline urban soil显示文摘Biochar has been considered as a potential way to enhance acidophilous plant growth in alkaline soils.However,whether such enhancements are closely linked with biochar pyrolysis temperature and its improvements in rhizospheric soil fertility and microbial activities remains largely unknown.We performed a pot experiment to investigate changes in azalea(Rhodo-dendron)morphology and physiology,as well as its rhizosphere soil chemical and biological properties in a slightly alkaline urban soil under the amendment of biochars that pyrolyzed at three temperatures(i.e.,350,550 and 700°C).Our results showed that the effects of biochars on plant growth and soil properties depended on pyrolysis temperature.In comparison with the non-amended control,350 and 550°C biochars showed significant promotions on the azalea growth in terms of photosynthetic characteristics,biomass,root morphology,and N and P uptake.Whereas,700°C biochar showed an inhibi-tion effect on them.350°C biochar decreased soil pH and increased soil available P and K contents and the activities ofα-glucosidase,N-β-glucosaminidase,phosphatase and sulfatase.In addition,350°C biochar significantly enhanced bacterial 16S rRNA and fungal 18S rRNA gene abundances in the rhizosphere soil of azalea and mycorrhizal infection.Correlation analysis indicated that soil pH,available nutrients and fungal abundance had positive associations with the enhanced plant growth parameters.Therefore,our findings suggest that biochar produced at low temperature could be a feasible strategy for enhancing acidophilous azalea growth and improving urban soil quality. | Huimin Zhou Xiaoying Li Chang Li Lisi He Xiaoqing Liu Zheng Xiao Xiaobo Sun Gaoling Shi Jiale Su Junhui Chen | 2021 | Biochar2021，3，4： | 1 |
| 9 | Influence of contaminations on combustion kinetics in hydrogen-fueled engine显示文摘In this work,we investigate the combustion of hydrogen fuel through the wind tunnel tests.Two kinds of fuel,the pure hydrogen and the hydrogen-ethene mixture,have been chosen to heat the oxygen-enriched air.It is found that the stable pressure in the engine combustor and the thrusts is almost the same in two cases.A valuable feature we revealed is that the heating pattern of hydrogen and ethene mixture leads to a considerable delay of the establishment of the wall pressure in the combustor,compared with the pure hydrogen case.This phenomenon implies a longer ignition delay time for the mixture case.The shorter ignition delay resulting from the hydrogen heater is attributed to the continuity of chain propagation and the exclusion of the less active C-containing radicals. | LIU WeiXiong HE Wei LI HongBin LI XiangYuan LE JiaLing | 2009 | Chinese Science Bulletin2009，54，8： | 1 |
| 10 | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex显示文摘In Saccharomyces cerevisiae,cryptic transcription at the coding region is prevented by the activity of Sin3 histone deacetylase(HDAC)complex Rpd3S,which is carried by the transcribing RNA polymerase Ⅱ(RNAPⅡ)to deacetylate and stabilize chromatin.Despite its fundamental importance,the mechanisms by which Rpd3S deacetylates nucleosomes and regulates chromatin dynamics remain elusive.Here,we determined several cryo-EM structures of Rpd3S in complex with nucleosome core particles(NCPs),including the H3/H4 deacetylation states,the alternative deacetylation state,the linker tightening state,and a state in which Rpd3S co-exists with the Hho1 linker histone on NCP.These structures suggest that Rpd3S utilizes a conserved Sin3 basic surface to navigate through the nucleosomal DNA,guided by its interactions with H3K36 methylation and the extra-nucleosomal DNA linkers,to target acetylated H3K9 and sample other histone tails.Furthermore,our structures illustrate that Rpd3S reconfigures the DNA linkers and acts in concert with Hho1 to engage the NCP,potentially unraveling how Rpd3S and Hho1 work in tandem for gene silencing. | Shuqi Dong Huadong Li Meilin Wang Nadia Rasheed Binqian Zou Xijie Gao Jiali Guan Weijie Li Jiale Zhang Chi Wang Ningkun Zhou Xue Shi Mei Li Min Zhou Junfeng Huang He Li Ying Zhang Koon Ho Wong Xiaofei Zhang William Chong Hang Chao Jun He | 2023 | Cell Research2023，33，10： | 1 |
| 11 | Rapid Preparation Process of Silver Nanoparticles by Bioreduction and Their Characterizations 1 1 Supported by the National Natural Science Foundation of China (No.20376076).显示文摘 | Mouxing FU Qingbiao LI Daohua SUN Yinghua LU Ning HE Xu DENG Huixuan WANG Jiale HUANG | 2006 | Chinese Journal of Chemical Engineering2006，，1： | 1 |
| 12 | Skeleton Keypoints Extraction Method Combined with Object Detection显示文摘Big data is a comprehensive result of the development of the Internet of Things and information systems.Computer vision requires a lot of data as the basis for research.Because skeleton data can adapt well to dynamic environment and complex background,it is used in action recognition tasks.In recent years,skeleton-based action recognition has received more and more attention in the field of computer vision.Therefore,the keypoints of human skeletons are essential for describing the pose estimation of human and predicting the action recognition of the human.This paper proposes a skeleton point extraction method combined with object detection,which can focus on the extraction of skeleton keypoints.After a large number of experiments,our model can be combined with object detection for skeleton points extraction,and the detection efficiency is improved. | Jiabao Shi Zhao Qiu Tao Chen Jiale Lin Hancheng Huang Yunlong He d Yu Yang | 2022 | Journal of New Media2022，4，2： | 0 |
| 13 | Numerical Simulation of Integrative Flow Field for Hypersonic Vehicle显示文摘To meet the requirements for the aerodynamic performance and thrust force demanded in hypersonic missions, the integration design of fuselage and. engine must be considered for hypersonic vehicle with a scramjet engine. The configuration of wave rider is a typical hypersonic vehicle shape, whose fore-body can compress the flow in advance and provide uniform flow for the air intake, and whose aft-body,is used as an expansion surface of nozzle. In the present paper, an engineering method is applied to define total aerodynamic characteristics of an approximate wave rider configuration. A finite volume method based on the center of grid is also employed to numerically investigate the outflow pass the same configuration. The flow field details and the aerodynamic characteristics at given conditions are obtained. The evaluation for this configuration may be used as a guide for the hypersonic vehicle experiment. | HE Yuanyuan LE Jialing NI Hongli Computational Aerodynamic Institute, China Aerodynamic Research and Development Center, Mianyang Sichuan 621000, China | 2001 | Journal of Thermal Science2001，10，2： | 0 |
| 14 | Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma显示文摘Gliomas are the most prevalent and aggressive malignancies of the nervous system.Previous bioinformatic studies have revealed the crucial role of the secretory pathway kinase FAM20C in the prediction of glioma invasion and malignancy.However,little is known about the pathogenesis of FAM20C in the regulation of glioma.Here,we construct the full-length transcriptome atlas in paired gliomas and observe that 22 genes are upregulated by full-length transcriptome and differential APA analysis.Analysis of ATAC-seq data reveals that both FAM20C and NPTN are the hub genes with chromatin openness and differential expression.Further,in vitro and in vivo studies suggest that FAM20C stimulates the proliferation and metastasis of glioma cells.Meanwhile,NPTN,a novel cancer suppressor gene,counteracts the function of FAM20C by inhibiting both the proliferation and migration of glioma.The blockade of FAM20C by neutralizing antibodies results in the regression of xenograft tumors.Moreover,MAX,BRD4,MYC,and REST are found to be the potential trans-active factors for the regulation of FAM20C.Taken together,our results uncover the oncogenic role of FAM20C in glioma and shed new light on the treatment of glioma by abolishing FAM20C. | Bo Gong Yi Liang Qian Zhang Huan Li Jialing Xiao Liang Wang Han Chen Wenjie Yang Xiaoqing Wang Yi Wang Zongze He | 2023 | Journal of Genetics and Genomics2023，50，6： | 0 |
| 15 | Identification of oleic acid as an endogenous ligand of GPR3显示文摘Although GPR3 plays pivotal roles in both the nervous system and metabolic processes,such as cold-induced thermogenesis,its endogenous ligand remains elusive.Here,by combining structural approach(including cryo-electron microscopy),mass spectrometry analysis,and functional studies,we identify oleic acid(OA)as an endogenous ligand of GPR3.Our study reveals a hydrophobic tunnel within GPR3 that connects the extracellular side of the receptor to the middle of plasma membrane,enabling fatty acids to readily engage the receptor.Functional studies demonstrate that OA triggers downstream Gs signaling,whereas lysophospholipids fail to activate the receptor.Moreover,our research reveals that cold stimulation induces the secretion of OA in mice,subsequently activating Gs/cAMP/PKA signaling in brown adipose tissue.Notably,brown adipose tissues from Gpr3 knockout mice do not respond to OA during cold stimulation,reinforcing the significance of GPR3 in this process.Finally,we propose a“born to be activated and cold to enhance”model for GPR3 activation.Our study provides a starting framework for the understanding of GPR3 signaling in cold-stimulated thermogenesis. | Yangjie Xiong Zhenmei Xu Xinzhi Li Yuqin Wang Jing Zhao Na Wang Yaning Duan Ruixue Xia Zhengbin Han Yu Qian Jiale Liang Anqi Zhang Changyou Guo Asuka Inoue Yu Xia Zheng Chen Yuanzheng He | 2024 | Cell Research2024，34，3： | 0 |
| 16 | Translation Model Construction of“Geda”as a Partitive in The Lantern Bearer from the Perspective of Cultural Schema Theory显示文摘The word“geda”,as a typical example of partitive in Shaanxi local dialect,appears 40 times in Jia Pingwa’s novel Daideng,but with varied translation equivalents in its English version The Lantern Bearer,where this article raised its doubts about how a proper translation of partitive can transmit culture in a more authentic and loyal way.From the perspective of cultural schema theory,this article takes The Lantern Bearer1 as the basis of text analysis to explore the translation strategy of the partitive“geda”in the context of cultural correspondence before relevant translation models are proposed with the purpose to shed light on Shaanxi local literature translation into English. | HE Jiale | 2022 | Cultural and Religious Studies2022，10，9： | 0 |
| 17 | Wet nitrogen oxidation technology and its anisotropy influence on VCSELs显示文摘Vertical cavity surface emitting lasers(VCSELs) are widely used in optical communications and optical interconnects due to their advantages of low threshold, low power consumption and so on. Wet nitrogen oxidation technology, which utilizes H20 molecules to oxidize the Al_(0.98)Ga_(0.02)As, is used for electrical and optical mode confinement. In this paper, the effects of oxidation time, oxidation temperature and oxidation anisotropy on the oxidation rate are explored and demonstrated. The ratio of oxidation rate on [0-11] to [011] crystal orientation is defined as oxidation anisotropy coefficient, which decreases with the increase of oxidation temperature and oxidation time. In order to analyze the effect of the oxidation anisotropy on the VCSEL performance, an oxide-aperture of the VCSELs with two difference shapes is designed and then fabricated. The static performance of these fabricated VCSELs has been measured,whose threshold current ratio ~0.714 is a good agreement with that of the theoretical calculation value ~0.785. Our research on wet nitrogen oxidation and its anisotropy serves as an important reference in the batch fabrication of large-area VCSELs. | Yan He Xiaoying He Shuai Hu Jiale Su Chong Li Anqi Hu Xia Guo | 2018 | Journal of Semiconductors2018，39，12： | 0 |
| 18 | Application and Challenge of Blockchain Technology in Medical Field显示文摘Due to its unique security,blockchain technology is widely used in the financial field.Under the background of the rapid development of information technology and the rapid improvement of medical level,it is also a general trend to integrate blockchain technology into the medical field.According to the characteristics of blockchain and the research contents of many scholars on the application of blockchain in the medical field,this paper analyzes and summarizes the problems existing in the current development of blockchain,puts forward corresponding solutions,and looks forward to the further application of blockchain technology in the medical field. | Kaifeng Zhang Zhao Qiu Gengquan Xie Jiale Lin Tingting Zhang Yingsheng Lian Tao Chen Yunlong He Yu Yang | 2022 | Journal of Cyber Security2022，4，2： | 0 |
| 19 | Efficiency and safety of acupuncture for women with premature ovarian insufficiency:study protocol for a randomized controlled trial显示文摘Acupuncture has been widely used as an alternative and complementary therapy for premature ovarian insufficiency(POI)in China.However,research to date has not shown that acupuncture is effective for POI compared with hormone replacement therapy(HRT).We will conduct a randomized,controlled,and outcome assessor-blind trial to evaluate the efficacy and safety of acupuncture on POI.Seventy-six patients with POI will be randomly assigned to two groups.The treatment group will receive twenty-eight one-hour sessions of acupuncture treatments,and the control group will receive 12-week HRT.The whole study will consist of a 12-week treatment plan and a 12-week follow-up session.The primary outcome is measured by changes in serum anti-Müllerian hormone and follicle-stimulating hormone(FSH)levels at weeks 12 and 24.Secondary outcome measures include estradiol,luteinizing hormone(LH),LH/FSH ratio,Kupperman index,and menstrual condition.This trial is expected to clarify whether or not acupuncture is effective and safe for POI compared with HRT. | XU Yani ZHANG Yutong HE Weile DAI Linglin TANG Ding WANG Jialing ZHANG Xufen CHEN Qin CHEN Lifang WANG Zhanglian ZHAN Mingjie | 2023 | Journal of Traditional Chinese Medicine2023，43，6： | 0 |
| 20 | Analysis on the Psychology and Behavior of Individual Investors under the Influence of COVID-19显示文摘Due to the relatively short history of the development of the Chinese stock market,the investment philosophy and psychology of most individual investors are not particularly mature.Especially under the influence of public health emergencies,the individual investors’characteristic of the investment behavior in the stock market has become more obvious.This paper combines questionnaire and psychological experiments to study the factors that affect investment decisions of individual investors,and then takes COVID-19 as an example to analyze the impact of public emergencies on individual investors’investment decisions in the stock market. | Jialing Huang Yixin He | 2020 | Proceedings of Business and Economic Studies2020，3，5： | 0 |
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