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| 1 | In-situ construction of a Mg-modified interface to guide uniform lithium deposition for stable all-solid-state batteries显示文摘Uniform lithium(Li)deposition in all-solid-state Li metal batteries is greatly influenced by the anode/electrolyte interface.Herein,a Mg-modified interface was constructed via the simple in-situ electrochemical reduction of Mg^(2+)from Mg(TFSI)_(2) in polyethylene oxide(PEO)and a Li bis(trifluoromethane)sulfoni mide(Li TFSI)formulae.As confirmed by cryogenic transmission electron microscopy,the anode/electrolyte interface exhibited hybrids consisting of crystalline Mg,Li_(2)O,and Li dots embedded in an amorphous polymer electrolyte.The crystalline Mg dots guided the uniform Li nucleation and growth,inducing a smoother anode/electrolyte interface compared with the pristine electrolyte.With 1 wt%Mg(TFSI)_(2) in the PEO-Li TFSI electrolyte,the Mg-modified electrolyte enabled the Li/Li symmetric cells with cycling performance of over 1700 and 1400 h at current densities of 0.1 and 0.2 m A cm^(-2),respectively.Moreover,the full LFP/Li cells using the novel Mg-modified electrolyte delivered a cycling lifespan of over 450 cycles with negligible capacity loss. | Tiefeng Liu Jiale Zheng Hualiang Hu Ouwei Sheng Zhijin Ju Gongxun Lu Yujing Liu Jianwei Nai Yao Wang Wenkui Zhang Xinyong Tao | 2021 | Journal of Energy Chemistry2021，30，4： | 3 |
| 2 | Impact of damping on high speed 850 nm VCSEL performance显示文摘High speed VCSELs are important optical devices in short-reach optical communication links and interconnects because of their low cost and high modulation speeds. In this paper, the impact of damping on the their static and dynamic characteristics is analyzed and demonstrated. Through the shallow corrosion of the top layer DBR, the VCSELs with different damping is designed and fabricated. With the increase of the surface etch depth from 0 to ~55 nm for 9 μm oxide-aperture VCSEL, the K factor related with the damping is reduced from0.31 to 0.23 ns^(-1). When the etch depth of the VCSEL with 9 μm oxide-aperture is decreased to ~25 nm,output power is increased from 4.03 to 4.70 mW and small signal modulation bandwidth is also increased from15.46 to 16.37 GHz. It shows that there is a tradeoff between damping and differential gain for improving modulation speed. | Shuai Hu Xiaoying He Yan He Jiale Su Chong Li Anqi Hu Xia Guo | 2018 | Journal of Semiconductors2018，39，11： | 2 |
| 3 | Effect of a viscoelastic target on the impact response of a flat-nosed projectile显示文摘Taylor impact is a widely used strategy in which a flat-nosed projectile is fired onto a rigid anvil directly to determine the dynamic strength of rod specimens. Nowadays, the rigid anvil is often replaced by an output target bar to ensure the accuracy of measurement via recording strain signals in the output bar. For testing the dynamic strength of low-density materials, a low-impedance target bar, which exhibits viscoelastic characteristics is often employed. In this paper, an extended Taylor model is proposed to improve the idealization of treating the target bar as perfectly rigid material in the classic Taylor model, and the viscoelastic effect of the target bar is incorporated. The viscoelastic target bar is depicted by two elastic springs and one dashpot. Based on the plastic shock wave theory in the flat-nosed projectile associated with the viscoelastic wave analysis in the target bar, the viscoelastic effect of the target bar on the impact response of the flat-nosed projectile is investigated. The finite element simulation is also carried out to verify the theoretical model,and good agreement is found. The present theoretical model is also called the Taylor-cylinder Hopkinson impact, which provides a more accurate way to identify the dynamic material parameters. The dynamic responses of the present model are further compared with previous elastic and rigid target bar models. It is found that the viscoelastic effect of the target bar should be taken into consideration in the Taylor-cylinder Hopkinson impact test for low-impedance materials. | Hu Liu Jialing Yang Hua Liu | 2018 | Acta Mechanica Sinica2018，34，1： | 2 |
| 4 | Effective nanotherapeutic approach for metastatic breast cancer treatment by supplemental oxygenation and imaging-guided phototherapy显示文摘Metastasis remains the primary cause for mortality of breast cancer.Despite advances in current therapeutic agents,patients with metastatic breast cancer still have poor prognoses.Tumor hypoxia,a key microenvironment factor,is emerging as an attractive target to prevent metastasis and is also involved with resistance to phototherapy.Here,we show an effective nanotherapeutic approach based on manganese dioxide-coated polydopamine nanocarriers to trigger robust anti-tumor and anti-metastasis responses against metastatic breast cancer by supplemental oxygenation and multimodal imaging-guided phototherapies.In cancer cells,the produced oxygen by the developed nanoplatform decreases the expression of hypoxia-inducible factors 1 a to inhibit tumor metastasis,and enhances the efficacy of photodynamic therapy.This nanotherapeutic approach enables the combined photodynamic/photothermal treatments with great inhibition on cell migration and invasion in vitro.Moreover,the nanotherapeutics effectively suppresses primary tumor progress and inhibits lung metastasis in v ivo in a breast cancer mouse model with satisfying biosafety.This study suggests that the tumor hypoxia-targeting nanotherapeutics have great potential for preventing and treating metastatic cancers. | Jialing Hu Fuan Wang Feng Liu Wentong Sun Qunying Jiang Yahua Liu Yun Zhao Xiaoqing Liu | 2020 | Nano Research2020，13，4： | 1 |
| 5 | Atmospheric Particle Hygroscopicity and the Influence by Oxidation State of Organic Aerosols in Urban Beijing显示文摘A hygroscopic tandem differentialmobility analyser(H-TDMA)was used to observe the sizeresolved hygroscopic characteristics of submicron particles in January and April 2018 in urban Beijing.The probability distribution of the hygroscopic growth factor(HGF-PDF)in winter and spring usually showed a bimodal pattern,with more hygroscopic mode(MH)being more dominant.The seasonal variation in particle hygroscopicity was related to the origin of air mass,which received polluted southerly air masses in spring and clean northwesterly air masses in winter.Particles showed stronger hygroscopic behaviour during heavy pollution episodes(HPEs)with elevated concentrations of secondary aerosols,especially higher mass fraction of nitrate,which were indicated using the PM2.5(particulate matter with diameter below 2.5μm)mass concentration normalised by CO mass concentration.The hygroscopic parameter(κ)values were calculated using H-TDMA(κhtdma)and chemical composition(κchem).The closure study showed thatκchem was overestimated in winter afternoon when compared withκhtdma,because the organic particle hygroscopic parameter(κorg)was overestimated in the calculations.It was influenced by the presence of a high concentration of hydrocarbon-like organic aerosol(HOA)with a weak water uptake ability.A positive relationship was observed betweenκorg and the ratio of oxygenated organic aerosol(OOA)and HOA,thereby indicating that the strong oxidation state enhanced the hygroscopicity of the particles.This study revealed the effect of local emission sources and secondary aerosol formation processes on particle hygroscopicity,which is of great significance for understanding the pollution formation mechanism in the North China Plain. | Sinan Zhang Xiaojing Shen Junying Sun Yangmei Zhang Xiaoye Zhang Can Xia Xinyao Hu Junting Zhong Jialing Wang Shuo Liu | 2023 | Journal of Environmental Sciences2023，，2： | 1 |
| 6 | Identification of Genes Involved in Immune Response, Microsatellite, and SNP Markers from Expressed Sequence Tags Generated from Hemocytes of Freshwater Pearl Mussel (Hyriopsis cumingii)显示文摘 | Zhiyi Bai Yuxin Yin Songnian Hu Guiling Wang Xiaowei Zhang Jiale Li | 2009 | Marine Biotechnology2009，，4： | 1 |
| 7 | Genetic Research and Utilization Reference of Saccharum spontaneum L.显示文摘[Objectives]The genetic characteristics of wild germplasm resources of Saccharum spontaneum L.were further investigated to provide a scientific theoretical basis for the improved hybridization of sugarcane varieties.[Methods]The first flowering date data of 112 wild resources were statistically analyzed by broad heritability for 3 consecutive years,and pollen quantity and yield were investigated to provide reference for hybridization.[Results]The broad heritability of the first flowering date of S.spontaneum was 0.079.The differences in the first flowering date between the S.spontaneum resources were in the range of 4-49 d,with an average of 13.65 d.The inter-annual changes within 20 d accounted for 90 %,and only 4.5% exceeded 30 d.The first flowering dates of some S.spontaneum resources were obviously postponed after being treated.[Conclusions]In the hybridization season,the hybridization plan must be adjusted according to the actual situation of the flowering period to make full use of it. | Jiale JI Qinnan WANG Yongsheng QIU Cheng FU Qiwei WU Houxiang HU Feng ZHOU Chuiming ZHANG Huanying XU Jing XIE | 2019 | Agricultural Biotechnology2019，8，3： | 1 |
| 8 | Rif1 interacts with non-canonical polycomb repressive complex PRC1.6 to regulate mouse embryonic stem cells fate potential显示文摘Mouse embryonic stem cells(mESCs)cycle in and out of a transient 2-cell(2C)-like totipotent state,driven by a com-plex genetic circuit involves both the coding and repetitive sections of the genome.While a vast array of regulators,including the multi-functional protein Rif1,has been reported to influence the switch of fate potential,how they act in concert to achieve this cellular plasticity remains elusive.Here,by modularizing the known totipotency regulatory factors,we identify an unprecedented functional connection between Rif1 and the non-canonical polycomb repres-sive complex PRC1.6.Downregulation of the expression of either Rif1 or PRC1.6 subunits imposes similar impacts on the transcriptome of mESCs.The LacO-LacI induced ectopic colocalization assay detects a specific interaction between Rif1 and Pcgf6,bolstering the intactness of the PRC1.6 complex.Chromatin immunoprecipitation followed by sequencing(ChIP-seq)analysis further reveals that Rif1 is required for the accurate targeting of Pcgf6 to a group of genomic loci encompassing many genes involved in the regulation of the 2C-like state.Depletion of Rif1 or Pcgf6 not only activates 2C genes such as Zscan4 and Zfp352,but also derepresses a group of the endogenous retroviral element MERVL,a key marker for totipotency.Collectively,our findings discover that Rif1 can serve as a novel auxiliary component in the PRC1.6 complex to restrain the genetic circuit underlying totipotent fate potential,shedding new mechanistic insights into its function in regulating the cellular plasticity of embryonic stem cells. | Lu Li Pishun Li Jiale Chen Li Li Yunfan Shen Yangzixuan Zhu Jiayi Liu Lu Lv Song Mao Fang Chen Guang Hu Kai Yuan | 2022 | Cell Regeneration2022，11，1： | 1 |
| 9 | Design of readout electronics based on peak-holding circuit and multiplexer for a fast neutron spectrometer显示文摘Background Fast neutron detection is meaningful in many research fields such as space environment monitoring.A scintillating fiber array model for fast neutron detection was proposed and developed in 1980s.Aerospace applications of the model require electronics in small size.Purpose To design a dedicated electronic system to readout and process the 384-channel signals from scintillating fiber array,and to use the designed system to fabricate a neutron detector for aerospace applications.Methods With the method of nuclear recoil,fast neutron is detected by tracking recoil proton of n–p scatter in scintillating plastic fibers.Using the peak-holding circuits and multiplexers,the system size and power consumption were reduced.Results The detector fabricated with the designed system,had 34 cm×34 cm×27 cm mechanical size,20.4 kg weight,and 30.05W power consumption.Comparing to traditional waveform sampling electronics,the designed electronics was highly integrated and had a small size.The readout electronics also gave a better energy resolution of 39%in neutron detection,while the energy resolution was 43%in previous version.Conclusion In this study,a highly integrated readout electronic system was designed and verified.The detector using the system gave good performance.The designed electronics had potential development in fast neutron detection and other high energy physics detection system. | Liyang Sun Kai Zhuang Xiaoming Wang Fanjian Zeng Heng An Daowu Li Yuxiong Xue Zhiming Zhang Wei Zhou Yingjie Wang Baotong Feng Peilin Wang Xiaohui Li Jiale Cai Teng Tong Fanhui Meng Junguang Zhou Huan Huang Xuanhou Hu Xiubo Qin | 2018 | Radiation Detection Technology and Methods2018，2，1： | 1 |
| 10 | Identification of Immune Genes of the Agamaki Clam (Sinonovacula constricta) by Sequencing and Bioinformatic Analysis of ESTs显示文摘 | Bingbing Feng Lingli Dong Donghong Niu Shanshan Meng Bing Zhang Dabo Liu Songnian Hu Jiale Li | 2010 | Marine Biotechnology2010，，3： | 1 |
| 11 | Consensus on the health education of home-based negative pressure wound therapy for patients with chronic wounds:a modified Delphi study显示文摘Background:The study aimed to develop consensus on the components of health education of home-based negative pressure wound therapy(NPWT)for patients with chronic wounds.Methods:A Delphi method was used to achieve consensus on the components of health education and 75%agreement and coefficient of variation(CV)<0.25 were used as cutoff.Sixteen experts were recruited purposefully to finish this study.Results:Two rounds of consultation were implemented.Consensus was achieved on 36 of the 42 statements.The final agreed list of statements represented three domains:health education before carrying out home-based NPWT,health education for the treatment day of NPWT at hospital and health education for NPWT at home.Conclusions:This study was the first attempt to develop consensus on the comprehensive components of health education of home-based NPWT for patients with chronic wounds.According to the established framework and components of health education,wound professionals can safely and effectively implement health education of home-based NPWT for patients with chronic wounds and improve their self-care ability and treatment experience at home. | Yao Huang Beiqian Mao Jiale Hu Bing Xu Pengwen Ni Lili Hou Ting Xie | 2021 | Burns & Trauma2021，9，1： | 1 |
| 12 | Identification of Genes Involved in Immune Response, Microsatellite, and SNP Markers from Expressed Sequence Tags Generated from Hemocytes of Freshwater Pearl Mussel (Hyriopsis cumingii)显示文摘 | Zhiyi Bai Yuxin Yin Songnian Hu Guiling Wang Xiaowei Zhang Jiale Li | 2009 | Marine Biotechnology2009，，4： | 1 |
| 13 | Overexpressing a NAM,ATAF,and CUC (NAC) transcription factor enhances drought resistance and salt tolerance in rice显示文摘 | Hu Honghong Dai Mingqiu Yao Jialing | 2006 | Proc Natl Acad Sci USA2006，103，12： | 1 |
| 14 | Characterization of a novel regulatory pathway for mannitol metabolism and its coordination with biofilm formation in Mycobacterium smegmatis显示文摘Biofilm formation has been implicated to be tightly regulated in bacteria. Mycobacterial species possess a unique cell-wall structure; however, the underlying regulation mechanism for their biofilm formation remains largely unclear. In this study, we characterized a hypothetical mannitol metabolism and transportation gene cluster(Ms5571-Ms5576), designated as mmt operon, whose expression significantly contributes to the biofilm formation in Mycobacterium smegmatis. We showed that in the operon the Ms5575 gene encodes a GntR-like transcriptional repressor and the Ms5576 gene encodes a mannitol2-dehydrogenase which can produce D-mannitol from D-mannose. Strikingly, the D-mannitol molecule can derepress the negative regulation of Ms5575 on the mmt operon to stimulate the operon's expression. Consistently, addition of D-mannitol into the medium can obviously induce mycobacterial biofilm formation. Furthermore, we found that Ms0179 positively regulates the mmt operon through its downstream regulator Ms0180. Ms0180 directly binds the mmt operon to positively regulate its expression. Both Ms0179 and Ms0180 significantly affect the mycobacterial biofilm formation. Taken together, we explored a regulatory pathway for the mannitol metabolism and its coordination with the biofilm formation in M. smegmatis. This finding provides novel insights into the unique mechanism of biofilm formation regulation in mycobacteria. | Jialing Hu Hua Zhang Si Zhou Weihui Li Zheng-Guo He | 2018 | Journal of Genetics and Genomics2018，45，9： | 1 |
| 15 | Over- expressing a NAM, ATAF, and CUC (NAC) tran- scription factor enhances drought resistance and salt tolerance in riee显示文摘 | Hu Honghong Dai Mingqiu Yao Jialing | 2006 | Proe Natl Aead Sci USA2006，103，12： | 1 |
| 16 | Compact MPPC-based coded aperture imaging camera for dual-particle detection显示文摘Purpose Fast neutrons and gamma-ray imaging detection is an effective way to detect and identify radioactive material in the field of nuclear security.A compact coded aperture imaging(CAI)camera was designed to be sensitive to both gamma and neutron radiation based on plastic scintillators and multi-pixel photon counters(MPPC).Methods MPPCs coupling with the 13×13 pixelated plastic scintillators one-to-one were utilized to reduce the scale of the CAI system while maintaining good positional performance.The symmetric charge division(SCD)circuit was adopted to reduce the 169 signals output from the MPPC array to 26.Each waveform was collected and processed with four Domino Ring Sampler 4(DRS4)chips and two 16-channel analog-to-digital converter(ADC)modules.As the pulse shapes of fast neutrons would be broadened after elastic scattering multiple times in the scintillators,the Anger-Logic method was applied to eliminate multiple elastic scattering events so that good pulse shape discrimination(PSD)performance can be achieved.Results The imaging and detection ability of the camerawas evaluated using the 241Am-Be(5.9×10^(5) n/s)neutron source and 137Cs(370 MBq)gammasource.The camera can be used to detect fast neutrons(0.5–10 MeV)and gammarays(0.2–2.5MeV).Furthermore,it can implement efficient neutron/gamma PSD capabilities in the mixed-field environment.The figure of merit(FOM)of the camera calculated at 400keVee energy cut is 0.93.Conclusion A compact MPPC-based CAI camera was designed to detect and discriminate fast neutrons and gamma rays.Its good PSD performance was well suited to distinguish fast neutrons from gamma rays in a dual-particle environment.The portable design makes it promising for complex monitoring scenarios in nuclear security. | Jing Guo Xiaoyu Pang Jiale Cai Daowu Li Xiaoming Wang Xuanhou Hu Yue Yu Shuangquan Liu Xiuzuo Liang Yiwen Zhang Lei Shuai Long Wei | 2021 | Radiation Detection Technology and Methods2021，5，1： | 1 |
| 17 | Adsorption and desorption mechanisms on graphene oxide nanosheets: Kinetics and tuning显示文摘A knowledge of the adsorption and desorption behavior of sorbates on surface adsorptive site(SAS)is the key to optimizing the chemical reactivity of catalysts.However,direct identification of the chemical reactivity of SASs is still a challenge due to the limitations of characterization techniques.Here,we present a new pathway to determine the kinetics of adsorption/desorption on SASs of graphene oxide(GO)based on total internal reflectance fluorescence microscopy.The switching on and off of the fluorescent signal of SAS lit by carbon dots(CDs)was used to trace the adsorption process and desorption process.We find that sodium pyrophosphate(PPi)could increase the adsorption equilibrium of CDs thermodynamically and promote the substrate-assisted desorption pathway kinetically.At the single turnover level,it was disclosed that the species that can promote desorption may also be an adsorption promoter.Such discovery provides significant guidance for improving the chemical reactivity of the heterogeneous catalyst. | Xiaodan Qu Qiong Hu Zhongqian Song Zhonghui Sun Baohua Zhang Jialing Zhong Xuyou Cao Yuanjin Liu Bolin Zhao Zhenbang Liu Yujie Shen Yu Bao Zhenxin Wang Yuwei Zhang Li Niu | 2021 | The Innovation2021，2，3： | 0 |
| 18 | Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semiinter penetrating polymer network(Semi-IPN)for solar dermatitis显示文摘Solar dermatitis is an acute or chronic high incidence of skin injury caused by ultraviolet(UV)radiation based on strong sunlight,which seriously endangers people's health.In this study,we designed and demonstrated enzyme-catalyzed semi-inter penetrating polymer network(Semi-IPN)sprayable nanodrug-loaded hydrogels based on gelatin,3-(4-hydroxyphenyl)propionic acid(HPA),polyvinyl alcohol(PVA),glycerol,and dexamethasone sodium phosphate(DEXP)for solar dermatitis.The hydrogels had high water content,excellent biocompatibility,effective encapsulation and sustained release of nanodrugs,antiinflammatory,and strong anti-ultraviolet B(anti-UVB)radiation properties based on glycerol and phenol functional groups,but also controllable spray gelation mode to make them adhere well on the dynamic skin surfaces and achieve continuous transdermal drugs delivery for solar dermatitis.The sprayable nanodrug-loaded hydrogel systems could be used as a highly effective therapeutic method for solar dermatitis,and also provide a good strategy for designing novel nanodrug-loaded hydrogel delivery systems. | Jialing Yao Junfeng Hui Jing Yang Jiaxin Yao Chaoquan Hu Daidi Fan | 2022 | Nano Research2022，15，7： | 0 |
| 19 | Electrically programmable phase-change photonic memory for optical neural networks with nanoseconds in situ training capability显示文摘Optical neural networks (ONNs), enabling low latency and high parallel data processing withoutelectromagnetic interference, have become a viable player for fast and energy-efficient processing andcalculation to meet the increasing demand for hash rate. Photonic memories employing nonvolatile phase-change materials could achieve zero static power consumption, low thermal cross talk, large-scale, andhigh-energy-efficient photonic neural networks. Nevertheless, the switching speed and dynamic energyconsumption of phase-change material-based photonic memories make them inapplicable for in situ training.Here, by integrating a patch of phase change thin film with a PIN-diode-embedded microring resonator,a bifunctional photonic memory enabling both 5-bit storage and nanoseconds volatile modulation wasdemonstrated. For the first time, a concept is presented for electrically programmable phase-changematerial-driven photonic memory integrated with nanosecond modulation to allow fast in situ training and zerostatic power consumption data processing in ONNs. ONNs with an optical convolution kernel constructedby our photonic memory theoretically achieved an accuracy of predictions higher than 95% when testedby the MNIST handwritten digit database. This provides a feasible solution to constructing large-scalenonvolatile ONNs with high-speed in situ training capability. | Maoliang Wei Junying Li Zequn Chen Bo Tang Zhiqi Jia Peng Zhang Kunhao Lei Kai Xu Jianghong Wu Chuyu Zhong Hui Ma Yuting Ye Jialing Jian Chunlei Sun Ruonan Liu Ying Sun Wei.E.I.Sha Xiaoyong Hu Jianyi Yang Lan Li Hongtao Lin | 2023 | Advanced Photonics2023，5，4： | 0 |
| 20 | Wet nitrogen oxidation technology and its anisotropy influence on VCSELs显示文摘Vertical cavity surface emitting lasers(VCSELs) are widely used in optical communications and optical interconnects due to their advantages of low threshold, low power consumption and so on. Wet nitrogen oxidation technology, which utilizes H20 molecules to oxidize the Al_(0.98)Ga_(0.02)As, is used for electrical and optical mode confinement. In this paper, the effects of oxidation time, oxidation temperature and oxidation anisotropy on the oxidation rate are explored and demonstrated. The ratio of oxidation rate on [0-11] to [011] crystal orientation is defined as oxidation anisotropy coefficient, which decreases with the increase of oxidation temperature and oxidation time. In order to analyze the effect of the oxidation anisotropy on the VCSEL performance, an oxide-aperture of the VCSELs with two difference shapes is designed and then fabricated. The static performance of these fabricated VCSELs has been measured,whose threshold current ratio ~0.714 is a good agreement with that of the theoretical calculation value ~0.785. Our research on wet nitrogen oxidation and its anisotropy serves as an important reference in the batch fabrication of large-area VCSELs. | Yan He Xiaoying He Shuai Hu Jiale Su Chong Li Anqi Hu Xia Guo | 2018 | Journal of Semiconductors2018，39，12： | 0 |
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