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| 1 | On adjacent-vertex-distinguishing total coloring of graphs显示文摘In this paper, we present a new concept of the adjacent-vertex-distinguishing total coloring of graphs (briefly, AVDTC of graphs) and, meanwhile, have obtained the adjacent-vertex-distinguishing total chromatic number of some graphs such as cycle, complete graph, complete bipartite graph, fan, wheel and tree. | ZHANG Zhongfu, CHEN Xiang’en, LI Jingwen, YAO Bing, LU Xinzhong & WANG Jianfang College of Mathematics and Information Science, Northwest Normal University, Lanzhou 730070, China Department of Computer, Lanzhou Normal College, Lanzhou 730070, China Institute of Applied Mathematics, Lanzhou Jiaotong University, Lanzhou 730070, China College of Information and Electrical Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China Institute of Applied Mathematics, Chinese Academy of Sciences, Beijing 100080, China | 2005 | Science China Mathematics2005，48，3： | 173 |
| 2 | Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment显示文摘 | Shuping Zhang | 2015 | Cellular & Molecular Immunology2015，12，5： | 17 |
| 3 | Recognition on the forming-vanishing process and underlying mechanisms of the hypoxia off the Yangtze River estuary显示文摘On the basis of compiled multidisciplinary historical data in 2006–2007 and incorporation of relevant simulation results and remote sensing data, we performed an in-depth study of the generation and dissipation process of the hypoxic zone and its distribution morphology and structure off the Yangtze River estuary. Based on the hydrological circulation dynamics, reproduction of phytoplankton(leading to the decomposition of organic matter), and other factors, we comprehensively and systematically investigated the generation and dissipation of the hypoxic zone and underlying mechanisms for the seasonal variation in its position, explored the multi-factorial synergistic reactions during the generation and dissipation process of the hypoxic zone, and revealed the controlled mechanism for the morphology and structure of the hypoxic zone's distribution. Our studies indicate that in the winter and spring seasons, the hydrological environment off the Yangtze River estuary provides a water body with relatively low contents of dissolved oxygen(DO), which is the background for the formation of a hypoxic zone. After entering into the summer season, the hypoxic zone gradually develops towards the north and becomes mature. Because of the impact of the terrain, local decomposition of organic matter, and upwelling of the Kuroshio subsurface water in July–August, the hypoxic zone off the Yangtze River estuary exhibits the characteristics of discontinuous distribution in space and has a south and north 'dual-core' structure in the inner continental shelf. In addition, there is a hypoxic core in the eastern outer continental shelf. The degrees of hypoxia vary for different areas; they are strongest overall in the north, next strongest in the south; they are weakest on the outer continental shelf. In summer, the hypoxic zone in the north is related to the northward differentiation of the southern hypoxic zone and results from local development and intensification. In August, the hypoxic zone in the north reaches its peak, and after September, it rapidly retreats southward and disappears because of weakening stratification. In the fall, there is hypoxic zone along the coast of Zhejiang in the south, and there is also a low-DO area to the southwest of Jeju Island, with both zones disappearing rapidly. In addition, the change of dynamic environment also causes the low-DO area of the outer continental shelf to move outward in the fall. The variation in the intensity of the stratification and its cumulative effects as a barrier of vertical DO transportation over long periods of time have a significant impact on the degree of hypoxia in the hypoxic zone. In addition, the seasonal variations in the size of the stratified region, intensity of each current system/water mass, upwelling, front, and high-value area of phytoplankton biomass jointly restrict the extension of the hypoxic zone in the inner continental shelf and latitudinal(south-north direction) movement of its location off the Yangtze River estuary. The combined effect of dynamic factors, such as that of the Kuroshio subsurface water, causes a low-DO core in the outer continental shelf. The bottom cold water to the north of the East China Sea is the dynamic basis for the formation of the low-DO area to the southwest of Jeju Island during the fall season. The special seabed topography and mud area distribution off the Yangtze River estuary have a certain degree of influence on the development of the hypoxic zone. The generation and dissipation of the hypoxic zone and its distribution morphology off the Yangtze River estuary, and seasonal variation of its structure and position are a result of the synergistic effects of various factors. | WEI QinSheng WANG BaoDong CHEN JianFang XIA ChangShui QU DaPeng XIE LinPing | 2015 | Science China Earth Sciences2015，58，4： | 15 |
| 4 | Discovery of a male-biased mutant family and identification of a male-specific SCAR marker in gynogenetic gibel carp Carassius auratus gibelio显示文摘Gibel 鲤鱼(Carassius auratus gibelio ) 是一特别地有在自然产地的男性的次要的比率的 gynogenetic 种类,而是它的男起源和性决心机制是未知的。在这研究,一个偏导男性的变异的家庭从 gynogenetic gibel 鲤鱼被发现,并且一个男性特定的疤标记从变异的家庭被识别。正常精子发生被免疫荧光组织化学在男睾丸观察。将近相同的 AFLP 侧面在男性和女性之间被观察,但是一男性特定 86 bp AFLP 碎片被性水池 bulked segregant 分析并且单个屏蔽屏蔽。基于男性特定的 AFLP 碎片, 579 个 bp 序列的一个总数被染色体走克隆。随后,一个男性特定的疤标记被设计,并且男性特定的 DNA 碎片被证实稳定地被传给下一代并且一致地仅仅在男性检测了。 | Da Wang Huiling Mao Jinxia Peng Xiyin Li Li Zhou Jianfang Gui | 2009 | Progress in Natural Science:Materials International2009，19，11： | 11 |
| 5 | Oceanic environmental changes of subarctic Bering Sea in recent 100 years: Evidence from molecular fossils显示文摘The core sample B2-9 from the seafloor of the subarctic Bering Sea was dated with 210 Pb to obtain a consecutive sequence of oceanic sedimentary environments at an interval of a decade during 1890—1999. A variety of molecular fossils were detected, including n-alkanes, isoprenoids, fatty acids, sterols, etc. By the characteristics of these fine molecules (C27, C28, and C29 sterols) and their molecular indices (Pr/Ph, ∑C+22/∑C?21, CPI and C18∶2/C18∶0) and in con- sideration of the variation of organic carbon content, the 100-year evolution history of subarctic sea paleoenvironment was reestablished. It is indicated that during the past 100 years in the Arctic, there were two events of strong climate warming (1920—1950 and 1980—1999), which resulted in an oxidated sediment environment owing to decreasing terrigenous organic matters and increasing marine-derived organic matters, and two events of transitory climate cooling (1910 and 1970—1980), which resulted in a slightly reduced sediment environment owing to increasing terrigenous organic matters and decreasing marine-derived organic matters. It is re- vealed that the processes of warming/cooling alternated climate are directly related to the Arctic and global climate variations. | LU Bing CHEN Ronghua ZHOU Huaiyang WANG Zipan CHEN Jianfang ZHU Chun | 2005 | Science China Earth Sciences2005，48，4： | 11 |
| 6 | Quaternary biogenic opal records in the South China Sea: Linkages to East Asian monsoon, global ice volume and orbital forcing显示文摘Particulate fluxes investigated in the central South China Sea (SCS) during 1993―1996 indicate that opal flux can be used to show primary productivity change, which provides a foundation for tracing the evolutionary relationship between the surface productivity and East Asian monsoon in the SCS during the late Quaternary glacial and interglacial periods. Based on the studies of opal % and their mass accumulation rates (MAR) at the six sites recovered from the SCS during the “Resolution” ODP Leg 184 and “Sonne” 95 cruise of the Sino-Germany cooperation, opal % and their MARs increased evidently in the northern sites since 470―900 ka, and they enhanced and reduced, respectively, during the glacial and interglacial periods. Whereas they increased obviously in the southern sites since 420―450 ka, and they augmented and declined, respectively, during the interglacial and glacial periods. The vari- ability in opal % and their MARs in the late Quaternary glacial cyclicity indicate the “seesaw” pattern of surface productivity in the SCS. The winter monsoon intensified during the glacial periods, surface productivity increased and decreased, respectively, in the northern and southern SCS. The summer monsoon strengthened during the interglacial periods, surface productivity increased and decreased, respectively, in the southern and northern SCS. The cross spectral analyses between the opal % in the northern and southern SCS during the Quaternary and global ice volume (δ 18O) and orbital forcing (ETP) indicate that the East Asian winter and summer monsoons could be ascribed to the different drive mechanisms. On the orbital time scale, the global ice volume change could be a dominant factor for the winter monsoon intension and temporal variations. As compared with the winter monsoon, the correlative summer solar radiation with the obliquity and precession in the Northern Hemisphere could be a mostly controlling factor for the summer monsoon intension and temporal variations. | WANG RuJian JIAN ZhiMin XIAO WenShen TIAN Jun LI JianRu CHEN RongHua ZHENG YuLong CHEN JianFang | 2007 | Science China Earth Sciences2007，50，5： | 9 |
| 7 | Variations in paleoproductivity and the environmental implications over the past six decades in the Changjiang Estuary显示文摘Total organic carbon and organic carbon stable isotope, biogenic silica, chlorin were measured from a high resolution sediment core to indicate the variation in paleoproductivity and the environmental implications over the past decades (1942 to 1997) in the Changjiang Estuary. Based on these biomarkers, the shift in the phytoplankton community structure in the past decades was discussed in response to the long-term variations in nutrient concentrations and nutrient ratios. The results showed that the δ 13 C values varied from –26.15‰ to –19.5‰, suggesting the combined organic carbon sources of riverine and marine organisms. Based on the biogenic proxies, paleoproductivity changes were categorized into three stages: low production before 1950; an increase in production with the dominance of diatoms during 1950 to 1980, consistent with increasing of nutrient concentrations; a decrease in production after 1980 when the diatom production decreased while the production of non-silicious phytoplankton increased due to high nutrient inputs, and high N/P and P/Si ratios in the Changjiang Estuary. The sedimentation records also indicated that the riverine organic carbon increased since 1980. | JIN Haiyan CHEN Jianfang WENG Huanxin LI Hongliang ZHANG Weiyan XU Jie BAI Youcheng WANG Kui | 2010 | Acta Oceanologica Sinica2010，29，3： | 8 |
| 8 | Phytoplankton composition and its ecological effect in subsurface cold pool of the northern Bering Sea in summer as revealed by HPLC derived pigment signatures显示文摘CHEMTAX analysis of high-performance liquid chromatography(HPLC) pigment was conducted to study phytoplankton community structure in the northern Bering Sea shelf, where a seasonal subsurface cold pool emerges. The results showed that fucoxanthin(Fuco) and chlorophyll a(Chl a) were the most abundant diagnostic pigments, with the integrated water column values ranging from 141 to 2 160 μg/m2 and 477 to 5 535 μg/m2, respectively. Moreover, a diatom bloom was identified at Sta. BB06 with the standing stock of Fuco up to 9 214 μg/m3. The results of CHEMTAX suggested that the phytoplankton community in the northern Bering Sea shelf was dominated by diatoms and chrysophytes with an average relative contribution to Chl a of 80% and 12%, respectively, followed by chlorophytes, dinoflagellates, and cryptophytes. Diatoms were the absolutely dominant algae in the subsurface cold pool with a relative contribution exceeding 90%, while the contribution of chrysophytes was generally higher in oligotrophic upper water. Additionally, the presence of a cold pool would tend to favor accumulation of diatom biomass and a bloom that occurred beneath the halocline would be beneficial to organic matter sinks, which suggests that a large part of the phytoplankton biomass would settle to the seabed and support a rich benthic biomass. | ZHUANG Yanpei JIN Haiyan LI Hongliang CHEN Jianfang WANG Bin CHEN Fajin BAI Youcheng LU Yong TIAN Shichao | 2014 | Acta Oceanologica Sinica2014，33，6： | 7 |
| 9 | Variations in organic carbon loading of surface sediments from the shelf to the slope of the Chukchi Sea,Arctic Ocean显示文摘The content of organic carbon(OC) normalized to the specific surface area(SSA) of sediment is widely used to trace variations in OC loading(OC/SSA).This study presents observations of OC/SSA of surface sediments collected in the Chukchi Sea,a typical Arctic marginal sea.Shelf sediments exhibit much higher OC/SSA values than slope sediments in the study area.Compared with OC/SSA values reported from the East Siberian Shelf and Mackenzie River,the slope sediments possess lower OC loading.This abrupt decrease in OC/SSA is mostly related to the lower primary production on slope as well as possible oxidization processes.The results of linear regression analysis between OC and SSA indicate a sedimentary source rock for the OC in the Chukchi Sea sediments.Moreover,shelf sediments with low SSA possess a larger rock OC fraction than slope sediments do.The dataset of the present study enables a more thorough understanding of regional OC cycling in the Chukchi Sea. | LI Zhongqiao WANG Xinyi JIN Haiyan JI Zhongqiang BAI Youcheng CHEN Jianfang | 2017 | Acta Oceanologica Sinica2017，36，8： | 6 |
| 10 | Inorganic Carbon Parameters Responding to Summer Hypoxia Outside the Changjiang Estuary and the Related Implications显示文摘The eutrophication,hypoxia and coastal acidification are attracting more and more attention.In this study,inorganic carbon parameters,including dissolved inorganic carbon (DIC) ,total alkalinity (TA) and calculated partial pressure of CO2 (pCO2) ,obtained from a summer cruise in August,2009,were used to investigate their integrated response to biological processes accompanying the oxygen depletion in the areas off the Changjiang Estuary.According to the observations,the typical hypoxia occurred in the bottom water just outside the Changjiang Estuary with Dissolved Oxygen (DO) lower than 2.00 mg L 1.The biological uptake in the surface water and the decomposition of organic matter in the bottom water were fully coupled with each other.The high concentration of Chl_a (Chl_a=10.9μg L 1) and DO (9.25 mg L 1) ,profoundly decreased DIC concentration (1828μmol kg 1) and elevated pH (8.42) was observed in the surface water.The correspondingly increased DIC and depletion of oxygen were observed in the bottom water.The semi-quantitative analysis proved that the locally-produced phytoplankton,determined by primary productivity,was deposited to the bottom and contributed about 76%of total amount of the organic carbon decomposition in the bottom.However,in the bottom hypoxia (DO=2.05 mg L 1) area observed in the Southern Zhejiang coastal water,the responding patterns of inorganic carbon parameters deviated from the previous one.The expanding of Changjiang Diluted Water (CDW) ,the adding of Hangzhou Bay water (with high DIC concentration) and Coastal Current together modify the DIC background value in this area,and the local degeneration and upwelling process may also help to offset the local DIC removed by net biological uptake in surface water.In addition,when the mixing occurring in autumn,which may break the summer stratification,the excess release of high DIC in the bottom water to the subsurface water could have an important influence on coastal acidification and the CO2uptake capacity in this area. | WANG Bin CHEN Jianfang JIN Haiyan LI Hongliang XU Jie | 2013 | Journal of Ocean University of China2013，12，4： | 6 |
| 11 | Activation of Toll-like receptors signaling in non-small cell lung cancer cell line induced by tumor-associated macrophages显示文摘Background:Inflammation is often linked with the progress and poor outcome of lung cancer.The understanding of the relationship between tumor-associated macrophages(TAMs) and lung cancer cells involves in the underlying mechanism of inflammatory cytokine production.Toll-like receptors(TLRs) are engaged in promoting the production of pro-inflammatory cytokines and play an important role in tumor immunology.Methods:To investigate the mechanisms by which TAMs influence the production of pro-inflammatory cytokines in lung cancer cells,we established an in vitro coculture system using TAMs and human nonsmall cell lung cancer(NSCLC) cell line SPC-A1.Levels of interleukin(IL)-1β,IL-6 and IL-8 in SPC-A1 were evaluated by RT-PCR and cytometric bead array assay after being cocultured with TAMs.Expression changes of TLRs and TLRs signaling pathway proteins in SPC-A1 were further confirmed by RT-PCR and western blot.The level changes of IL-1β,IL-6 and IL-8 in SPC-A1 were also detected after the stimulation of TLRs agonists.Results:We found that the phenotype markers of TAMs were highly expressed after stimulating human monocyte cell line THP-1 by phorbol-12-myristate-13-acetate(PMA).Higher mRNA and supernate secretion levels of IL-1β,IL-6 and IL-8 were detected in SPC-A1 after being cocultured with TAMs.We also found that TLR1,TLR6 and TLR7 were up-regulated in SPC-A1 in the coculture system with TAMs.Meanwhile,TLRs signaling pathway proteins were also significantly activated.Moreover,pre-treatment with agonist ligands for TLR1,TLR6 and TLR7 could dramatically promote inductions of IL-1β,IL-6 and IL-8.Conclusions:These findings demonstrated that TAMs may enhance IL-1β,IL-6 and IL-8 expressions via TLRs signaling pathway.We conclude that TAMs contribute to maintain the inflammation microenvironment and ultimately promote the development and progression of lung cancer. | Xing Ke Meng Wu Jianfang Lou Shuping Zhang Peijun Huang Ruihong Sun Lei Huang Erfu Xie Fang Wang Bing Gu | 2015 | Chinese Journal of Cancer Research2015，27，2： | 6 |
| 12 | Mechanisms leading to the frequent occurrences of hypoxia and a preliminary analysis of the associated acidification off the Changiiang estuary in summer显示文摘Based on literature data and shipboard observations,this study investigated the main environmental characteristics of the seafloor topography,current field,front,and upwelling that are closely related to hypoxia occurrence off the Changjiang estuary.The physical processes of the plume front and upwelling off the Changjiang estuary in summer were coupled.The vertical distribution pattern of the plume front was closely related to the upwelling.By reviewing and analyzing the historical summer hypoxia events off the Changjiang estuary,we statistically demonstrated the spatial structure of the horizontal distribution of the hypoxic zone and investigated the location of occurrence zone of the hypoxia.We found that the dissolved oxygen(DO)concentration on the inner continental shelf off the estuary showed a'V'shape in relation to station depth.Therefore,we noted that the hypoxic water on the inner continental shelf mostly occurred on the slopes with steep seafloor topography.Base on the current understanding of the hypoxic mechanisms off the Changjiang estuary,we analyzed the biogeochemical mechanisms that could cause the steep terrain off the Changjiang estuary to become the main areas prone to summer hypoxia and explained the internal relations between the location of the hypoxic zone on the slopes and the plume front and upwelling.The plume front and upwelling off the Changjiang estuary and their coupling were important driving forces of summer hypoxia.The continuous supply of nutrients affected by the interaction of the plume front extension of the Changjiang Diluted Water(CDW)and upwelling and the favorable light conditions were important mechanisms causing the phytoplankton blooms and benthic hypoxia off the Changjiang estuary in summer.By analyzing oxygen utilization,organic carbon mineralization,and nutrient regeneration in the hypoxic zone,we observed that the significant oxygen utilization process off the Changjiang estuary in summer also mainly occurred near the steep slopes with front and upwelling features and confirmed the apparent nutrient loss in the benthic hypoxic zone.Meanwhile,our analysis revealed that the sediment resuspension in the benthic boundary layer in the mud areas off the Changjiang estuary could also affect the oxygen utilization and mineralization of organic carbon and nutrient recycling and regeneration.This study also demonstrated that the steep terrain off the Changjiang estuary was the main location for summer acidification,and the coupling between the plume front and upwelling on the steep slopes was an important physical driving force inducing summer benthic acidification.Finally,we discussed issues to address in future studies of the hypoxic zone and water acidification off the Changjiang estuary. | WEI QinSheng WANG BaoDong YU ZhiGang CHEN JianFang XUE Liang | 2017 | Science China Earth Sciences2017，60，2： | 5 |
| 13 | Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses显示文摘Human skeletal stem cells(SSCs)have been discovered in fetal and adult long bones.However,the spatiotemporal ontogeny of human embryonic SSCs during early skeletogenesis remains elusive.Here we map the transcriptional landscape of human limb buds and embryonic long bones at single-cell resolution to address this fundamental question.We found remarkable heterogeneity within human limb bud mesenchyme and epithelium,and aligned them along the proximal-distal and anterior-posterior axes using known marker genes.Osteo-chondrogenic progenitors first appeared in the core limb bud mesenchyme,which give rise to multiple populations of stem/progenitor cells in embryonic long bones undergoing endochondral ossification.Importantly,a perichondrial embryonic skeletal stem/progenitor cell(eSSPC)subset was identified,which could self-renew and generate the osteochondral lineage cells,but not adipocytes or hematopoietic stroma.eSSPCs are marked by the adhesion molecule CADM1 and highly enriched with FOXP1/2 transcriptional network.Interestingly,neural crest-derived cells with similar phenotypic markers and transcriptional networks were also found in the sagittal suture of human embryonic calvaria.Taken together,this study revealed the cellular heterogeneity and lineage hierarchy during human embryonic skeletogenesis,and identified distinct skeletal stem/progenitor cells that orchestrate endochondral and intramembranous ossification. | Jian He Jing Yan Jianfang Wang Liangyu Zhao Qian Xin Yang Zeng Yuxi Sun Han Zhang Zhijie Bai Zongcheng Li Yanli Ni Yandong Gong Yunqiao Li Han He Zhilei Bian Yu Lan Chunyu Ma Lihong Bian Heng Zhu Bing Liu Rui Yue | 2021 | Cell Research2021，31，7： | 5 |
| 14 | The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection显示文摘Epigenetic modifications to histones dictate the differentiation of naïve CD4^(+) T cells into different subsets of effector T helper(TH)cells.The histone methyltransferase enhancer of zeste homolog 2(EZH2)has been implicated in the mechanism regulating the differentiation of TH1,TH2 and regulatory T(Treg)cells.However,whether and how EZH2 regulates follicular helper T(TFH)cell differentiation remain unknown.Using a mouse model of acute lymphocytic choriomeningitis virus(LCMV)infection,we observed abundant EZH2 expression and associated H3K27me3 modifications preferentially in the early committed virus-specific TFH cells compared to those in TH1 cells.Ablation of EZH2 in LCMV-specific CD4^(+) T cells leads to a selective impairment of early TFH cell fate commitment,but not late TFH differentiation or memory TFH maintenance.Mechanistically,EZH2 specifically stabilizes the chromatin accessibility of a cluster of genes that are important for TFH fate commitment,particularly B cell lymphoma 6(Bcl6),and thus directs TFH cell commitment.Therefore,we identified the chromatin-modifying enzyme EZH2 as a novel regulator of early TFH differentiation during acute viral infection. | Xiangyu Chen Guoshuai Cao Jialin Wu Xinxin Wang Zhiwei Pan Jianbao Gao Qin Tian Lifan Xu Zhirong Li Yaxing Hao Qizhao Huang Pengcheng Wang Minglu Xiao Luoyingzi Xie Shupei Tang Zhenyu Liu Li Hu Jianfang Tang Ran He Li Wang Xinyuan Zhou Yuzhang Wu Mengjie Chen Beicheng Sun Bo Zhu Jun Huang Lilin Ye | 2020 | Cellular & Molecular Immunology2020，17，3： | 4 |
| 15 | Response of nutrients and the surface phytoplankton community to ice melting in the central Arctic Ocean显示文摘During the fourth Chinese National Arctic Research Expedition cruise in summer 2010, a time-series observation was carried out to examine the response of nutrients and phytoplankton community in the ice-water interface to the ice melting ice in the central Arctic Ocean. Phosphate and silicate in the ice-water interface were rich relative to dissolved inorganic nitrogen (DIN), based on the Redfield ratio (16N:1P:16Si), suggesting that DIN was the potential limiting nutrient. DIN concentrations in the sea ice were about 3-4 times that in the surface seawater, indicating that melting ice delivered DIN to the surface water. Pigment analysis showed that fucoxanthin and chlorophyll a contribute to carotenoids and chlorophylls in particles. The mean concentrations of chlorophyll c,diatoxanthin, diadinoxanthin and fucoxanthin from 15 August to 18 August were 6 μgm-3, 22 μgm-3, 73 μgm-3 and 922 μg·m-3, respectively, suggesting that diatoms dominated in the phytoplankton community composition.Furthermore, a notable enhancement in fucoxanthin and chlorophyll a during a large-scale ice melting was likely attributed to senescent diatoms released from the bottom sea-ice as well as phytoplankton diatoms growth in the water column due to the input of nutrients (i.e., DIN) and reducing light limitation from melting ice. Temporal distribution patterns of prasinoxanthin and lutein differed from fucoxanthin, indicating that the response of green algae and diatoms to ice melting were different. | ZHUANG Yanpei JIN Haiyan CHEN Jianfang WANG Bin LI Hongliang CHEN Fajin LU Yong XU Jie | 2011 | Advances in Polar Science2011，22，4： | 4 |
| 16 | Application of long-chain alkenones and U_(37)~k values for paleotemperature estimation in the Arctic Chukchi Sea-Bering Sea area显示文摘Long-chain alkenones were detected in samples of sea surface sediments from the Chukchi Sea and the Bering Sea areas, the Arctic Pole. The analysis result indicates that C37:3 methylketone is predominate in the long-chain alkenones from the Chukchi and Bering Sea sediments. The abundance of C37 to C39 unsaturated alkenones changes in an order of C37 > C38 > C39. Based on C37 /C38 ratio, the detected organism precursors of the long-chain alkenones are mainly coccolithophrid (Emiliania huxleyi). By the calibration relationship between U37k and U37k indices, the sea surface paleotemperature in these seas is estimated. The estimated values of U37k vary from 4.147℃ to 5.706℃ , with a mean value of 5.092℃. | Lu Bing, Chen Ronghua, Wang Zipan, Chen Jianfang, Liu Zhensheng 1. Key Laboratory of Submarine Geosciences, Second Institute of Oceanography, State Oceanic Administration, Hangzhou 310012, China | 2001 | Acta Oceanologica Sinica2001，20，3： | 4 |
| 17 | Climatic significance of n-alkanes and their compound-specific dD values from lake surface sediments on the Southwestern Tibetan Plateau显示文摘The content and hydrogen isotope ratios of n-alkanes extracted from recent lake surface sediments sampled from nine lakes in three different climate zones on the Southwestern Tibetan Plateau were analyzed.Values were compared with n-alkanes in plants from lake drainages,and dD values of meteoric water,lake water,and mean annual precipitation.The results showed that n-C23was predominantly derived from aquatic plants,and n-C27–n-C33from terrestrial higher plants.The average carbon chain length of n-C27–n-C33(ACL27–33)was positively correlated with the mean annual precipitation.dD values of the long-chain n-alkanes n-C29and n-C31of terrestrial origin(varying between-214%and-169%,and-226%and-185%,respectively)were inversely correlated with mean annual precipitation;but in accordance with the average annual variations in dD(OIPC),dD values of n-C31were strongly related to the dD values of growing season meteoric water(R2=0.74).The large difference between dD values of n-C23of aquatic origin and n-C31(an average of about 27%)demonstrates the enrichment of the lake water dD compared to precipitation,caused by strong evaporation in the semiarid–arid areas of the southwestern Tibetan Plateau.Average value of en C25 31=p(-95%)is evidently higher than the value observed in European wet regions(-128%);besides,en C31(about-116%)is constant along the study transect(SD=9),which indicates that n-C31is a useful proxy for the environment. | Xing Hu Liping Zhu Yong Wang Junbo Wang Ping Peng Qingfeng Ma Jianfang Hu Xiao Lin | 2014 | Chinese Science Bulletin2014，59，24： | 3 |
| 18 | Apolipoprotein C1 regulates epiboly during gastrulation in zebrafish显示文摘Apolipoprotein C1(Apoc1)is associated with lipoprotein metabolism,but its physiological role during embryogenesis is largely unknown.We reveal a new function of Apoc1b,a transcript isoform of Apoc1,in epiboly during zebrafish gastrulation.Apoc1b is expressed in yolk syncytial layers and in deep cells of the ventral and lateral region of the embryos.It displays a radial gradient with high levels in the interior layer and low levels in the superficial layer.Knockdown of Apoc1b by injecting antisense morpholino(MO)caused the epiboly arrest in deep cells.Moreover,we show that the radial intercalation and the radial gradient distribution of E-cadherin are disrupted both in Apoc1b knockdown and overexpressed embryos.Therefore,Apoc1b controls epiboly via E-cadherin-mediated radial intercalation in a gradient-dependent manner. | WANG Yang ZHOU Li LI Zhi LI WenHua GUI JianFang | 2013 | Science China(Life Sciences)2013，56，11： | 3 |
| 19 | Mechanism on minimization of excess sludge in oxic-settling- anaerobic (OSA) process显示文摘The oxic-settling-anaerobic(OSA)process is a promising wastewater treatment technique for efficiently reducing sludge production and improving the stability of process operation.In this paper,the possible factors of sludge reduction such as sludge decay,uncoupled metabol-ism,and anaerobic oxidation with low sludge production were discussed in the OSA process.It has been confirmed that sludge decay is the decisive cause in the OSA process,accounting for 66.7%of sludge production reduction.Sludge decay includes hydrolysis and acidogenesis of dead microorganisms and particle organic carbon adsorbed in sludge floc and endogenous metabolism.By batch experi-ments,it has been proven that there is energetic uncoupling in the OSA system since microorganisms were exposed to alternative anaerobic and aerobic environment.It accounts for about 7.5%of sludge production reduction.Soluble chemical oxygen demand(SCOD)released from the anaerobic sludge tank in the OSA process was used as the substrate for cryptic growth.The substrate was used for anoxic denitrifying,anaerobic phosphorus release,sulfate reduction,and methane production.These anaerobic reactions in the sludge anaerobic tank have lower sludge production than in the aerobic oxidation when equivalent SCOD is consumed,which may lead to approximately 23%of sludge reduction in the OSA process.It has been concluded that multiple causes resulted in the minimization of excess sludge in the OSA system.The microbial community structure and diversity of sludge samples from the CAS(conventional activated sludge)and OSA systems were investigated by 16 SrDNA PCR-DG-DGGE(poly-merase chain reaction-double gradient-denaturing gradient gel electrophoresis).DGGE profile and cluster analysis showed more abundant species in the OSA system contrasting to microbial communities in the CAS system. | Jianfang WANG Qingliang ZHAO Wenbiao JIN Jikan LIN | 2008 | Frontiers of Environmental Science & Engineering2008，2，1： | 3 |
| 20 | Mechanisms of carbon storage and the coupled carbon, nitrogen and sulfur cycles in regional seas in response to global change显示文摘1.Great challenges in scientific frontiers of marine carbon storage in the scenario of global change The marine carbon cycle is influenced by anthropogenic activities,affecting global climate change and casting a significant impact on ecosystems.However,the complex spatiotemporal process of the marine carbon cycle results in the uncertainty in the estimation of marine carbon budget。 | XIE ShuCheng CHEN JianFang WANG FengPing XUN LuYing TANG Kai ZHAI WeiDong LIU JiHua MA WenTao | 2017 | Science China Earth Sciences2017，60，5： | 3 |
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