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| 1 | A life support-based comprehensive treatment regimen dramatically lowers the in-hospital mortality of patients with fulminant myocarditis: a multiple center study显示文摘Fulminant myocarditis(FM) has unacceptable high mortality. This study aimed to evaluate the therapeutic efficacy of a life support-based comprehensive treatment regimen(LSBCTR), a completely novel treatment regimen, for FM. A total of 169 FM patients recruited from January 2008 to December 2018 were divided into two groups: patients receiving LSBCTR(81 cases),which includes(i) mechanical life support(positive pressure respiration, intra-aortic balloon pump with or without extracorporeal membrane oxygenation),(ii) immunomodulation therapy using sufficient doses of glucocorticoids and immunoglobulins, and(iii) application of neuraminidase inhibitors, and those receiving conventional treatment(88 cases). The endpoints were in-hospital death and heart-transplantation. Of all the population, 44 patients(26.0%) died in hospitals. Inhospital mortality was 3.7%(3/81) for LSBCTR group and 46.6%(41/88) for traditional treatment(P<0.001). Early application of LSBCTR, mechanical life support, neuraminidase inhibitors, and immunomodulation therapy significantly contributed to reduction in in-hospital mortality. This study describes a novel treatment regimen for FM patients that dramatically reduces inhospital mortality. Its generalization and clinical application will efficiently save lives although further optimization is needed.This study offers an insight that virus infection induced inflammatory waterfall results in cardiac injury and cardiogenic shock and is the therapeutic target. | Sheng Li Shengyong Xu Chenze Li Xiao Ran Guanglin Cui Mengying He Kun Miao Chunxia Zhao Jiangtao Yan Rutai Hui Ning Zhou Yan Wang Jiangang Jiang Jing Zhang Daowen Wang | 2019 | Science China(Life Sciences)2019，62，3： | 43 |
| 2 | Polymer nanodisks by collapse of nanocapsules显示文摘It is an important challenge to make disk-like polymeric nanostructures. Herein we report a facile method for preparing polymer nanodisks by self-collapse of nanocapsules self-assembled from a statistical copolymer after partial hydrolysis. We find that partial hydrolysis of the statistical copolymer is crucial for the formation of nanodisks as it affords a suitable rigidity for the membrane of nanocapsules. The nanodisk structure has been confirmed by transmission electron microscopy(TEM), scanning electron microscopy(SEM) and atomic force microscopy(AFM) studies with a thickness of 6.3±0.2 nm. Overall, our results demonstrated a new method for making disk-like nano-objects. | Jiangang Xiao Yu Hu Jianzhong Du | 2018 | Science China Chemistry2018，61，5： | 3 |
| 3 | AC loss and contact resistance in highly flexible rebco cable for fusion applications显示文摘High Temperature Superconductor(HTS)materials can operate at higher magnetic fields up to 20 T with high critical current and higher operating temperature,compared to low temperature superconductors(LTS).A Highly Flexible REBCO Cable(HFRC)is introduced at the Institute of Plasma Physics,Chinese Academy of Sciences(ASIPP);a cabling method that is suitable for REBCO HTS tape having anisotropic material properties in its thin REBCO layer.This type of HTS superconducting cable shows high potential for applications in nuclear fusion.The alternating currents and magnetic fields in tokamak type of fusion magnets,cause AC power losses in such cables,which can provoke instability of the conductor by induced currents and increase the temperature.As a first step in characterizing the electromagnetic(EM)performance of an HFRC cable,the AC loss and contact resistance of the HFRC prototype cable were measured at the University of Twente.The measurements were done in liquid helium(4.2 K)with AC magnetic fields,applied perpendicular to the cable's long axis.The AC loss was measured simultaneously by a calibrated gas flow calorimeter utilizing the helium boil-off method,and by the magnetization method using pick-up coils.For the applied test conditions,no coupling loss could be distinguished as a part of the overall AC loss.It is suggested that this might be explained by the shielding of the conductor interior from the applied magnetic field by the outer tape layer due to the high critical current density of the REBCO tape,leading to a high penetration field. | Zichuan Guo Jinggang Qin R.Lubkemann Keyang Wang Huan Jin Guanyu Xiao Jiangang Li Chao Zhou Arend Nijhuis | 2022 | Superconductivity2022，，2： | 2 |
| 4 | Spatio-temporal Dynamic Simulation of Land use and Ecological Risk in the Yangtze River Delta Urban Agglomeration,China显示文摘Rapid urbanization leads to dramatic changes in land use patterns,and the land use/cover change(LUCC)can reflect the spatial impact of urbanization on the ecological environment.Simulating the process of LUCC and predicting the ecological risk future changes can provide supports for urban ecological management.Taking the Yangtze River Delta Urban Agglomeration(YRDUA),China as the study area,four developmental scenarios were set on the basis of the land use data from 2005 to 2015.The temporal land use changes were predicted by the integration of the system dynamic and the future land use simulation(SD-FLUS)model,and the geographically weighted regression(GWR)model was used to identify the spatial heterogeneity and evolution characteristics between ecological risk index(ERI)and socio-economic driving forces.Results showed that:1)From 2005 to 2015,the expansion of construction land(7670.24 km^(2))mainly came from the occupation of cultivated land(7854.22 km2).The Kappa coefficient of the SD-FLUS model was 0.886,indicating that this model could be used to predict the future land use changes in the YRDUA.2)Gross domestic production(GDP)and population density(POP)showed a positive effect on the ERI,and the impact of POP exceeded that of GDP.The ERI showed the characteristics of zonal diffusion and a slight upward trend,and the high ecological risk region increased by 6.09%,with the largest increase.3)Under different developmental scenarios,the land use and ecological risk patterns varied.The construction land is increased by 5.76%,7.41%,5.25%and 6.06%,respectively.And the high ecological risk region accounted for 12.71%,15.06%,11.89%,and 12.94%,correspondingly.In Scenario D,the structure of land use and ecological risk pattern was better compared with other scenarios considering the needs of rapid economic and ecological protection.This study is helpful to understand the spatio-temporal pattern and demand of land use types,grasp the ecological security pattern of large-scale areas,and provide scientific basis for the territory development of urban agglomeration in the future. | WANG Xiao CHE Lei ZHOU Liang XU Jiangang | 2021 | Chinese Geographical Science2021，31，5： | 2 |
| 5 | Syringomyelia after operation:diagnosis and its formational mechanism显示文摘描述 MRI 调查结果并且在脊骨以后在病人讨论 syringomyelia 的致病形成机制的目的外科的操作。完全, 13 个病人在学习被注册的方法。在手术前,任何一个都没与针的绳索 syringomyelia 我们的病人介绍。吝啬的后续持续时间由 MRI 是 6 年(范围 210 月) 。在针的绳索肿瘤以后的 13 个病人中的四个移开操作,在针的损伤操作以后的 3 个病人, 2 个盒子以前有脊柱侧凸, 2 个盒子是颈的 spondylotic myelopathy, 2 个盒子以前拴住绳索症候群操作。操作前的先生特征并且在所有病人上操作以后与外科的结果和临床的症状在对比被学习。辐射学诊断被 3 个不同放射线学者分别地做。长度,宽度,信号,洞的形状以及 subarachnoid 形状的特征上被集中。结果所有病人以前没在 MRI 上有 syringomyelia 手术。7 个病人的针的绳索出现了坚持压缩和 2 个病人以前拴住绳索操作。在在我们的情况中的操作以后的 syringomyelia 的 MRI 特征证明有鸣管液体的纵的洞有脑髓的液体(CSF ) 的 T1 和 T2 关系特征。吝啬的长度是 5.5 针的片断, 13 个病人的 4 绳索介绍了从前面的材料压缩的绳索, 4 发生了对腰部的针的运河和 1 格的针的绳索的背的手术后的粘附依附颈的针的运河的前面墙。在在针的外科的干预以后的病人的 syringomyelia 的机制可以是在操作前的时期的针的绳索的坚持的压缩或意愿的结论或操作以后。浮肿,包囊,针的绳索的 malacia 是最重要的损害,风险因素导致 syringomyelia。 | Shi Jiangang Jia Lianshun Yuan Wen Shi Guodong Wu Jianfeng Ye XiaoJian Ni Bin Xiao Jianru Tan Junming Xu Guohua | 2008 | Journal of Medical Colleges of PLA(China)2008，23，2： | 1 |
| 6 | LC–MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii显示文摘 | Xiuling Li Hongbin Xiao Xinmiao Liang Dazhuo Shi Jiangang Liu | 2003 | Journal of Pharmaceutical and Biomedical Analysis2003，，1： | 1 |
| 7 | Study on the Aromatic Components of Green Plum Wine by HS-SPME-GC-MS显示文摘In order to better blend green plum wine and study aromatic components of green plum wine,a qualitative analysis on aromatic components of soaked base liquor,green plum soaked wine,green plum juice,and fermented wine of green plum juice by Head Space Solid-phase Microextraction( HS-SPME) and Gas Chromatograph Mass Spectrometer( GC-MS) was studied in this paper. Experiment results indicated that14,32,17,and 46 kinds of aromatic components were identified respectively from four samples. Different aromatic components determined the special flavor and taste of green plum wine. Unique aromatic components generated in soaking process include benzaldehyde,1-butanol,2-methyl-,S-(-),benzoic acid ethyl ester,and 5-( hydroxymethyl). Special aromatic components in green plum juice were furfural,phenylethyl alcohol,and benzyl alcohol. The aromatic components in fermented wine of green plum juice mainly included phenylethyl alcohol( 6. 941%,relative content of peak area,same below),1-butanol,3-methyl-( 6. 940%),octanoic acid,ethyl ester( 3. 734%),decanoic acid,ethyl ester( 2. 590%),hexanoic acid,ethyl ester( 2. 479%),ethyl 9-decenoate( 2. 080%),and 5-hydroxymethyl( 1. 756%). This study was expected to provide scientific basis and data reference for quality improvement of green plum wine. | Yingying MA Hechuan WU Qingbin LIU Lingyun WANG Xiao DOU Lin YANG Jiangang YANG | 2016 | Asian Agricultural Research2016，8，1： | 1 |
| 8 | Identification and analysis of intermediate-size noncoding RNAs in the rhesus macaque fetal brain显示文摘Although only about 2%of the human genome has proved to be protein-coding genes,recent advances in genome wide analysis have revealed that the majority of the genome is transcribed,mainly from noncoding segments that were once considered'junk sequences'or'dark matters'(Liu et al.,2011a;Zhang et al., | Liyuan Zhu Xiaochao Tan Wei Liu Fengbiao Mao Chao Wu Junjie Zhou Xiao Liu Shuaiyao Lu Kaili Ma Bin Yin Jianjun Luo Jiangang Yuan Boqin Qiang Runsheng Chen Xiaozhong Peng | 2017 | Journal of Genetics and Genomics2017，44，3： | 0 |
| 9 | Application of osteoinductive calcium phosphate ceramics in children’s endoscopic neurosurgery:report of five cases显示文摘This work aimed at investigating the possibility and effectiveness of osteoinductive calcium phosphate(CaP)ceramics to close the drilled skull holes and prevent the postoperative cerebrospinal fluid(CSF)leaking in children’s endoscopic neurosurgery.Five children patients(four boys and one girl,3-to 8-years old)underwent the surgery,in which the endoscopic third ventriculostomy(ETV)was operated in four cases of hydrocephalus,and biopsy and ETV were both performed in one case of pineal tumor.The drilled skull holes were filled with the commercial osteoinductive CaP ceramics.The patients were followed up by CT scan at 1,7 days,3 and 6 months postoperatively.All the five cases were successful,and the holes were closed well after filled with the ceramics.The follow-up survey showed that no CSF leaking or rejection reaction was found.The CT scan indicated that the drilled holes began healing at 7 days postoperatively,and a relatively complete healing happened at 6 months postoperatively.The excellent ability of the CaP ceramics to induce bone regeneration was also confirmed by repairing the skull defects in a monkey model.The results of μ-CT and histological analysis showed that a bony structure with irregular array occurred at the defect area,and the newly formed bone volume density reached 65.7%.In conclusion,the osteoinductive CaP ceramics could be an ideal material to treat the drilled skull holes in children’s endoscopic neurosurgery and prevent CSF leaking afterwards.However,further investigation with more cases and longer follow-up was required to evaluate the clinical effect. | Jia Wei Hufei Qian Yu Liu Jiangang Liu Rui Zhao Xiao Yang Xiangdong Zhu Ruoping Chen Xingdong Zhang | 2018 | Regenerative Biomaterials2018，5，4： | 0 |
| 10 | Chlorine-substituted chiral 2D perovskite microwires with enhanced lattice rigidity for sensitive circularly polarized light detection显示文摘Chiral two-dimensional(2D) perovskites offer numerous attractive features for optoelectronics owing to their soft, deformable lattices and a high degree of chemical tunability. While tremendous advances have been made in perovskite-based direct circularly polarized light(CPL) detection, the low circular polarization anisotropy factor and sensitivity of those photodetectors arising from large lattice distortion still limit practical applications. Herein, chiral 2D perovskite-based single-crystalline microwire arrays with enhanced circular dichroism(CD) absorption are fabricated with the synergy of the capillary-bridgeconfined assembly method and chlorine-substituted phenethylamine(Cl-MBA). Compared with phenethylamine(MBA)-inserted perovskites, the smaller lattice distortion and increased halogen–halogen interaction within Cl–MBA-inserted perovskites strengthen lattice rigidity and weaken electron–phonon coupling to improve carrier transport and thermal stability, resulting in high-performance CPL photodetectors with an anisotropy factor of 0.25, responsivity exceeding 95.7±9.3 A W^(-1)and detectivity exceeding(3.05±0.30)×10^(13)Jones. This work opens a new perspective to modulate circular polarization sensitivity and will be helpful to realize promising implementations in quantum computation and communication. | Meng Yuan Yuchen Qiu Yingjie Zhao Yuyan Zhao Hui Li Xiao Wei Gaosong Chen Jiangang Feng Hanfei Gao Jinjin Zhao Jiahui Zhao Lei Jiang Yuchen Wu | 2023 | Science China Chemistry2023，66，12： | 0 |
| 11 | Sea-urchin-like ReS_(2) nanosheets with charge edge-collection effect as a novel cocatalyst for high-efficiency photocatalytic H_(2) evolution显示文摘The recombination of charge carriers arriving from the random charge movement in semiconductor pho-tocatalysts greatly limits the practical application of solar-driven H_(2)evolution.The design of photo-catalytic systems with spatially oriented charge-transfer is a promising route to achieve high charge-separation efficiency for photocatalysts.Herein,novel sea-urchin-like Re S_(2)nanosheet/TiO_(2)nanoparticle heterojunctions(SURTHs)are constructed.The unique sea-urchin-like structure endows the ReS_(2)cocat-alyst with an unusual charge edge-collection effect,which leads to a significant acceleration of charge separation and transfer,as evidenced by the well-designed selective photodeposition of Pt quantum dots in SURTHs.The markedly improved charge transfer capacity contributes to a high photocatalytic H_(2)evo-lution rate of 3.71 mmol h^(−1)g^(−1)for SURTHs(an apparent quantum efficiency(AQE)of 16.09%),up to 231.9 times by contrast with that of P25 TiO_(2).This work would provide a new platform for designing the high-efficiency cocatalyst/photocatalyst system with excellent charge transfer capacity. | Bo Lin Bowen Ma Jiangang Chen Yao Zhou Jiadong Zhou Xiaoqing Yan Chao Xue Xiao Luo Qing Liu Jinyong Wang Renji Bian Guidong Yang Fucai Liu | 2022 | Chinese Chemical Letters2022，33，2： | 0 |
| 12 | Regulation voltage of LiNiPO_(4) by density functional theory(DFT)calculation to move towards practical application显示文摘LiNiPO_(4)(working at~5.1 V)shows potential advantages in the competition of cathode materials for lithium-ion batteries(LIBs)because of high energy density.However,the high-voltage electrolyte developed can only remain relatively stable in the range of less than 4.8V,so the operating voltage of LiNiPO_(4)needs to be adjusted to smaller to better exploit its high-voltage advantages.To regulate the operating voltage of LiNiPO_(4)while ensuring the relative stability of its electrochemical properties,in this work,all the 3d,4d,and 5d transition metals(TMs)are,respectively,doped into the Ni site of LiNiPO_(4)to screen out the doped models with excellent electrochemical performance.In particular,the changes in lattice structure,electronic properties,formation energy,mechanical properties,anisotropy,and working voltage were used as screening criteria.By considering the above screening criteria,the Cr-and Fe-doped LiNiPO_(4)with open circuit voltage~4.7 and~4.8 V are considered to have leading performance and can be used for applicable high-voltage LIBs.The screening results of this work can provide an overall understanding of the doping of LiNiPO_(4)by TMs and have advanced a theoretical idea for the design of new high-voltage LIBs cathode materials. | Bo Zhang Yufang He Aiping Wang Xiang Xiao Jinli Liu Yingqiang Wu Li Wang Hong Xu Jiangang Li Hao Zhang Xiangming He | 2023 | Interdisciplinary Materials2023，2，3： | 0 |
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